IQCE

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1acrosome reaction (GO:0007340)5.92710022
2cilium or flagellum-dependent cell motility (GO:0001539)5.42648808
3protein polyglutamylation (GO:0018095)5.24653046
4regulation of somitogenesis (GO:0014807)5.19968319
5sperm motility (GO:0030317)5.13180089
6auditory receptor cell differentiation (GO:0042491)4.97810101
7fusion of sperm to egg plasma membrane (GO:0007342)4.75895991
8axoneme assembly (GO:0035082)4.58149359
9acrosome assembly (GO:0001675)4.57161813
10axonemal dynein complex assembly (GO:0070286)4.47353463
11epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.24330268
12epithelial cilium movement (GO:0003351)4.23642069
13locomotory exploration behavior (GO:0035641)4.18282173
14male meiosis (GO:0007140)4.17980426
15cilium movement (GO:0003341)4.09392479
16sperm capacitation (GO:0048240)3.98253931
17sperm-egg recognition (GO:0035036)3.90302199
18spermatid development (GO:0007286)3.85271067
19regulation of cilium movement (GO:0003352)3.77244775
20motile cilium assembly (GO:0044458)3.69004029
21plasma membrane fusion (GO:0045026)3.65945415
22establishment of apical/basal cell polarity (GO:0035089)3.63860439
23cell wall macromolecule catabolic process (GO:0016998)3.63844214
24cell wall macromolecule metabolic process (GO:0044036)3.63844214
25ventricular system development (GO:0021591)3.63072269
26pentose metabolic process (GO:0019321)3.62249050
27microtubule bundle formation (GO:0001578)3.61095896
28cell-cell recognition (GO:0009988)3.60086098
29calcium ion-dependent exocytosis (GO:0017156)3.58126065
30negative regulation of inclusion body assembly (GO:0090084)3.55804227
31vocalization behavior (GO:0071625)3.53138497
32multicellular organism reproduction (GO:0032504)3.52695891
33binding of sperm to zona pellucida (GO:0007339)3.51370169
34regulation of skeletal muscle cell differentiation (GO:2001014)3.47641320
35cytoskeletal anchoring at plasma membrane (GO:0007016)3.46491510
36semaphorin-plexin signaling pathway (GO:0071526)3.43828400
37ear development (GO:0043583)3.39430159
38hair cell differentiation (GO:0035315)3.37984914
39regulation of short-term neuronal synaptic plasticity (GO:0048172)3.37726652
40establishment of monopolar cell polarity (GO:0061162)3.37049516
41establishment or maintenance of monopolar cell polarity (GO:0061339)3.37049516
42layer formation in cerebral cortex (GO:0021819)3.33967039
43synaptic vesicle docking involved in exocytosis (GO:0016081)3.32576882
44neuronal ion channel clustering (GO:0045161)3.31032943
45cellular sodium ion homeostasis (GO:0006883)3.30551865
46fat-soluble vitamin catabolic process (GO:0042363)3.29410624
47vitamin catabolic process (GO:0009111)3.29410624
48positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.26690041
49piRNA metabolic process (GO:0034587)3.25186256
50auditory behavior (GO:0031223)3.24891633
51inner ear receptor cell differentiation (GO:0060113)3.19284959
52lung epithelium development (GO:0060428)3.18922054
53peptidyl-tyrosine autophosphorylation (GO:0038083)3.18744769
54endocardial cushion morphogenesis (GO:0003203)3.12818183
55positive regulation of Notch signaling pathway (GO:0045747)3.10626272
56Notch signaling involved in heart development (GO:0061314)3.05597871
57reproduction (GO:0000003)3.00876584
58positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.98729357
59synaptonemal complex organization (GO:0070193)2.95934294
60cerebellar Purkinje cell layer development (GO:0021680)2.95563682
61glomerular epithelial cell development (GO:0072310)2.95213090
62insulin-like growth factor receptor signaling pathway (GO:0048009)2.94112938
63neuroblast proliferation (GO:0007405)2.91720960
64cerebellar Purkinje cell differentiation (GO:0021702)2.91316901
65sexual reproduction (GO:0019953)2.90835255
66aorta morphogenesis (GO:0035909)2.87768275
67genitalia morphogenesis (GO:0035112)2.86897422
68dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.86746611
69apical protein localization (GO:0045176)2.86182348
70regulation of NFAT protein import into nucleus (GO:0051532)2.85274341
71mechanoreceptor differentiation (GO:0042490)2.83158107
72cell-cell junction maintenance (GO:0045217)2.82529484
73synaptonemal complex assembly (GO:0007130)2.80009122
74establishment of nucleus localization (GO:0040023)2.79123096
75microtubule severing (GO:0051013)2.77594155
76negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.75630133
77cerebellar granule cell differentiation (GO:0021707)2.74271103
78neuronal stem cell maintenance (GO:0097150)2.71135328
79regulation of interleukin-5 production (GO:0032674)2.70306210
80left/right pattern formation (GO:0060972)2.70265171
81regulation of interleukin-13 production (GO:0032656)2.70130212
82cilium assembly (GO:0042384)2.69803489
83exploration behavior (GO:0035640)2.69697610
84cilium organization (GO:0044782)2.69411802
85camera-type eye morphogenesis (GO:0048593)2.68073130
86primary alcohol catabolic process (GO:0034310)2.67913830
87single fertilization (GO:0007338)2.66918443
88mechanosensory behavior (GO:0007638)2.66455307
89regulation of microtubule-based movement (GO:0060632)2.66396584
90asymmetric protein localization (GO:0008105)2.66117090
91left/right axis specification (GO:0070986)2.65177899
92stress granule assembly (GO:0034063)2.63915252
93vitamin transmembrane transport (GO:0035461)2.63580796
94regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.63299020
95microtubule-based movement (GO:0007018)2.63246562
96dendritic spine organization (GO:0097061)2.62527647
97regulation of ARF protein signal transduction (GO:0032012)2.62069896
98cochlea development (GO:0090102)2.60602609
99regulation of inclusion body assembly (GO:0090083)2.60502512
100intraciliary transport (GO:0042073)2.58822150
101melanin biosynthetic process (GO:0042438)2.58599556
102phosphatidylethanolamine biosynthetic process (GO:0006646)2.58109850
103RNA localization (GO:0006403)2.56061911
104spermatogenesis (GO:0007283)2.55971570
105sodium ion export (GO:0071436)2.55141654
106protein localization to cilium (GO:0061512)2.54983437
107male gamete generation (GO:0048232)2.54162887
108planar cell polarity pathway involved in neural tube closure (GO:0090179)2.54075367
109centriole assembly (GO:0098534)2.53326720
110protein-DNA complex disassembly (GO:0032986)2.53018781
111nucleosome disassembly (GO:0006337)2.53018781
112regulation of cilium assembly (GO:1902017)2.52369080
113cell recognition (GO:0008037)2.52084986
114synaptic vesicle maturation (GO:0016188)2.51291045
115negative regulation of organelle assembly (GO:1902116)2.49402506
116innervation (GO:0060384)2.49397330
117establishment or maintenance of apical/basal cell polarity (GO:0035088)2.48117531
118establishment or maintenance of bipolar cell polarity (GO:0061245)2.48117531
119establishment of planar polarity (GO:0001736)2.48042603
120establishment of tissue polarity (GO:0007164)2.48042603
121retrograde transport, vesicle recycling within Golgi (GO:0000301)2.47263840
122response to auditory stimulus (GO:0010996)2.45637387
123lipid translocation (GO:0034204)2.44171105
124phospholipid translocation (GO:0045332)2.44171105
125membrane depolarization during action potential (GO:0086010)2.41893204
126regulation of autophagic vacuole assembly (GO:2000785)2.41859805
127dopamine receptor signaling pathway (GO:0007212)2.41831617
128glutamate secretion (GO:0014047)2.40106455
129regulation of glutamate receptor signaling pathway (GO:1900449)2.39691584
130mesenchyme morphogenesis (GO:0072132)2.39267891
131synaptic vesicle endocytosis (GO:0048488)2.38099576
132regulation of ARF GTPase activity (GO:0032312)2.37478157
133protein targeting to Golgi (GO:0000042)2.36412947
134cell migration in hindbrain (GO:0021535)2.36186460
135dendrite morphogenesis (GO:0048813)2.35572904
136establishment of protein localization to Golgi (GO:0072600)2.35432887
137positive regulation of histone deacetylation (GO:0031065)2.35206041
138macroautophagy (GO:0016236)2.35078484
139positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.35063133
140vesicle transport along microtubule (GO:0047496)2.34950052
141fertilization (GO:0009566)2.34690705
142regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.34546374
143synaptic vesicle exocytosis (GO:0016079)2.34188759
144neuron recognition (GO:0008038)2.32712975
145regulation of chromatin binding (GO:0035561)2.32702950
146positive regulation of skeletal muscle tissue development (GO:0048643)2.32606027
147meiotic nuclear division (GO:0007126)2.31913942
148axonal fasciculation (GO:0007413)2.31679962
149phosphatidylethanolamine metabolic process (GO:0046337)2.30463747
150positive regulation of smoothened signaling pathway (GO:0045880)2.29918755
151regulation of fatty acid beta-oxidation (GO:0031998)2.29669374
152adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.28009439
153endothelial cell chemotaxis (GO:0035767)2.26939060
154diterpenoid biosynthetic process (GO:0016102)2.26184039
155dendritic spine morphogenesis (GO:0060997)2.25778627
156embryonic body morphogenesis (GO:0010172)2.25102924
157microtubule polymerization or depolymerization (GO:0031109)2.24285177
158melanin metabolic process (GO:0006582)2.21091242
159embryonic camera-type eye development (GO:0031076)2.21038015
160cell junction maintenance (GO:0034331)2.20425553
161receptor recycling (GO:0001881)2.19931365
162phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.18829438
163response to acidic pH (GO:0010447)2.18781096
164regulation of Rab GTPase activity (GO:0032313)2.18310241
165positive regulation of Rab GTPase activity (GO:0032851)2.18310241
166protein retention in ER lumen (GO:0006621)2.17589967
167cell projection assembly (GO:0030031)2.16680389
168ethanol metabolic process (GO:0006067)2.15760801
169microtubule depolymerization (GO:0007019)2.14678649
170amyloid precursor protein catabolic process (GO:0042987)2.14652928
171myelin maintenance (GO:0043217)2.14541520
172desmosome organization (GO:0002934)2.14008682
173cellular component assembly involved in morphogenesis (GO:0010927)2.13848239
174negative regulation of catenin import into nucleus (GO:0035414)2.13256256

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.75154197
2ESR2_21235772_ChIP-Seq_MCF-7_Human2.85990015
3ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.79815543
4ESR1_20079471_ChIP-ChIP_T-47D_Human2.50319379
5EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.49023953
6IKZF1_21737484_ChIP-ChIP_HCT116_Human2.45358213
7CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.41492290
8DROSHA_22980978_ChIP-Seq_HELA_Human2.27881769
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.25116934
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.22605641
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.10526088
12PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.10455383
13RACK7_27058665_Chip-Seq_MCF-7_Human2.05824351
14SUZ12_27294783_Chip-Seq_ESCs_Mouse2.02049261
15ESR1_21235772_ChIP-Seq_MCF-7_Human2.00654555
16TRIM28_21343339_ChIP-Seq_HEK293_Human1.98507923
17RUNX1_27514584_Chip-Seq_MCF-7_Human1.96819570
18MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.92952675
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.85613054
20REST_21632747_ChIP-Seq_MESCs_Mouse1.81593143
21RARB_27405468_Chip-Seq_BRAIN_Mouse1.78927977
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.78823626
23EZH2_27294783_Chip-Seq_ESCs_Mouse1.76138627
24* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.76007647
25P68_20966046_ChIP-Seq_HELA_Human1.74295606
26RARG_19884340_ChIP-ChIP_MEFs_Mouse1.70728914
27RNF2_18974828_ChIP-Seq_MESCs_Mouse1.60712047
28EZH2_18974828_ChIP-Seq_MESCs_Mouse1.60712047
29MTF2_20144788_ChIP-Seq_MESCs_Mouse1.58845828
30JARID2_20064375_ChIP-Seq_MESCs_Mouse1.54785451
31KDM2B_26808549_Chip-Seq_K562_Human1.53095868
32SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.51750066
33TP63_22573176_ChIP-Seq_HFKS_Human1.50661932
34BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.50589929
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.48111897
36RING1B_27294783_Chip-Seq_ESCs_Mouse1.47683087
37CREB1_26743006_Chip-Seq_LNCaP_Human1.47442497
38WT1_25993318_ChIP-Seq_PODOCYTE_Human1.46249319
39KDM2B_26808549_Chip-Seq_DND41_Human1.45770035
40WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.45196589
41DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.44149700
42NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.43474988
43KLF5_25053715_ChIP-Seq_YYC3_Human1.39305909
44KDM2B_26808549_Chip-Seq_SUP-B15_Human1.38730101
45* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.37748857
46CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.37333019
47TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.37266863
48POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.37266863
49ELK4_26923725_Chip-Seq_MESODERM_Mouse1.36359617
50TCF7_22412390_ChIP-Seq_EML_Mouse1.34312096
51SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.34190413
52SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.33860800
53EZH2_27304074_Chip-Seq_ESCs_Mouse1.32395537
54EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.31794250
55ARNT_22903824_ChIP-Seq_MCF-7_Human1.31540654
56ZFP281_27345836_Chip-Seq_ESCs_Mouse1.30508442
57ZNF274_21170338_ChIP-Seq_K562_Hela1.29427644
58ZNF217_24962896_ChIP-Seq_MCF-7_Human1.28557214
59TET1_21451524_ChIP-Seq_MESCs_Mouse1.28225615
60AHR_22903824_ChIP-Seq_MCF-7_Human1.27885466
61SMAD3_21741376_ChIP-Seq_ESCs_Human1.27811395
62TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.27610846
63TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27364628
64UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.24907701
65SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.24469995
66ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.24384399
67REST_18959480_ChIP-ChIP_MESCs_Mouse1.24251967
68ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23392133
69WDR5_24793694_ChIP-Seq_LNCAP_Human1.22557869
70SA1_27219007_Chip-Seq_ERYTHROID_Human1.22110362
71MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.21650607
72SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.21309573
73JARID2_20075857_ChIP-Seq_MESCs_Mouse1.21260827
74KDM2B_26808549_Chip-Seq_JURKAT_Human1.21017689
75SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.20833040
76GBX2_23144817_ChIP-Seq_PC3_Human1.20785603
77ELK3_25401928_ChIP-Seq_HUVEC_Human1.19473858
78CTNNB1_20460455_ChIP-Seq_HCT116_Human1.18231158
79ELF1_20517297_ChIP-Seq_JURKAT_Human1.17877151
80RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.17658523
81SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.17636476
82CTBP2_25329375_ChIP-Seq_LNCAP_Human1.14879933
83TP53_23651856_ChIP-Seq_MEFs_Mouse1.14854659
84ERG_21242973_ChIP-ChIP_JURKAT_Human1.14525360
85NFIB_24661679_ChIP-Seq_LUNG_Mouse1.13923537
86TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.13073041
87PHF8_20622854_ChIP-Seq_HELA_Human1.11615845
88BCOR_27268052_Chip-Seq_Bcells_Human1.11119748
89SOX2_27498859_Chip-Seq_STOMACH_Mouse1.11034376
90E2F1_20622854_ChIP-Seq_HELA_Human1.10808281
91KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.09853951
92* LXR_22292898_ChIP-Seq_THP-1_Human1.09410313
93* TP53_22127205_ChIP-Seq_IMR90_Human1.08564128
94DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08525392
95SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.07369421
96CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.07170672
97ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.06734259
98BCL6_27268052_Chip-Seq_Bcells_Human1.06569787
99P63_26484246_Chip-Seq_KERATINOCYTES_Human1.06531360
100CTCF_20526341_ChIP-Seq_ESCs_Human1.06522975
101PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.06144961
102ZNF263_19887448_ChIP-Seq_K562_Human1.05853514
103KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.05522156
104KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.04931202
105* SOX9_24532713_ChIP-Seq_HFSC_Mouse1.04930740
106* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04812195
107* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04132122
108VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.04118897
109ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.04072745
110ISL1_27105846_Chip-Seq_CPCs_Mouse1.03503999
111TET1_21490601_ChIP-Seq_MESCs_Mouse1.03296317
112SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.03275696
113TDRD3_21172665_ChIP-Seq_MCF-7_Human1.03273545
114OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.02494334
115TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02176187
116SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.01722560
117RING1B_27294783_Chip-Seq_NPCs_Mouse1.01127703
118P300_27058665_Chip-Seq_ZR-75-30cells_Human1.00621777
119CTCF_27219007_Chip-Seq_Bcells_Human1.00345082
120CTCF_27219007_Chip-Seq_ERYTHROID_Human1.00057653
121RAD21_21589869_ChIP-Seq_MESCs_Mouse0.99528059
122* SMC4_20622854_ChIP-Seq_HELA_Human0.97947216
123* AR_19668381_ChIP-Seq_PC3_Human0.97275499
124EED_16625203_ChIP-ChIP_MESCs_Mouse0.94791934
125VDR_21846776_ChIP-Seq_THP-1_Human0.94719604
126PKCTHETA_26484144_Chip-Seq_BREAST_Human0.94264144
127TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.94043797
128PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.91576269
129OCT4_19829295_ChIP-Seq_ESCs_Human0.91172673
130ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.90642822
131TCF4_23295773_ChIP-Seq_U87_Human0.88102557
132TAF15_26573619_Chip-Seq_HEK293_Human0.87141101
133* SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.86635187
134SMAD4_21799915_ChIP-Seq_A2780_Human0.86234292
135SOX2_21211035_ChIP-Seq_LN229_Gbm0.85445275
136RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.84091751
137CTBP1_25329375_ChIP-Seq_LNCAP_Human0.83612278
138YAP1_20516196_ChIP-Seq_MESCs_Mouse0.82526315
139STAT3_23295773_ChIP-Seq_U87_Human0.82438675
140RNF2_27304074_Chip-Seq_NSC_Mouse0.82328645
141MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.82305659
142TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.81977441
143CBP_20019798_ChIP-Seq_JUKART_Human0.81342401

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot5.19772358
2MP0003878_abnormal_ear_physiology5.19772358
3MP0005410_abnormal_fertilization4.93091962
4MP0003879_abnormal_hair_cell4.37467383
5MP0002653_abnormal_ependyma_morphology3.94391214
6MP0001485_abnormal_pinna_reflex3.65570776
7MP0004859_abnormal_synaptic_plasticity3.15637023
8MP0000569_abnormal_digit_pigmentation2.98106826
9MP0005409_darkened_coat_color2.90871676
10MP0003136_yellow_coat_color2.65353174
11MP0010234_abnormal_vibrissa_follicle2.50065834
12MP0000678_abnormal_parathyroid_gland2.45518697
13MP0009780_abnormal_chondrocyte_physiolo2.30127729
14MP0000566_synostosis2.29036963
15MP0003787_abnormal_imprinting2.27299599
16MP0003705_abnormal_hypodermis_morpholog2.25432629
17MP0003698_abnormal_male_reproductive2.21911932
18MP0008877_abnormal_DNA_methylation2.20978658
19MP0001963_abnormal_hearing_physiology2.18667085
20MP0005248_abnormal_Harderian_gland2.12916306
21MP0005623_abnormal_meninges_morphology2.05062542
22MP0000026_abnormal_inner_ear2.02471003
23MP0003283_abnormal_digestive_organ1.97648995
24MP0008961_abnormal_basal_metabolism1.88606254
25MP0003635_abnormal_synaptic_transmissio1.84671666
26MP0001486_abnormal_startle_reflex1.83185509
27MP0001348_abnormal_lacrimal_gland1.78119210
28MP0004885_abnormal_endolymph1.68007508
29MP0001929_abnormal_gametogenesis1.67842057
30MP0001984_abnormal_olfaction1.66860500
31MP0005083_abnormal_biliary_tract1.65917651
32MP0002063_abnormal_learning/memory/cond1.65829260
33MP0003329_amyloid_beta_deposits1.65707953
34MP0008875_abnormal_xenobiotic_pharmacok1.58190781
35MP0002089_abnormal_postnatal_growth/wei1.56781839
36MP0000778_abnormal_nervous_system1.52949578
37MP0000534_abnormal_ureter_morphology1.51350576
38MP0000681_abnormal_thyroid_gland1.46133802
39MP0002184_abnormal_innervation1.43898741
40MP0005076_abnormal_cell_differentiation1.43557395
41MP0004270_analgesia1.41958949
42MP0004264_abnormal_extraembryonic_tissu1.41605421
43MP0009745_abnormal_behavioral_response1.38494024
44MP0009278_abnormal_bone_marrow1.35186361
45MP0003172_abnormal_lysosome_physiology1.34130202
46MP0005257_abnormal_intraocular_pressure1.33839827
47MP0005645_abnormal_hypothalamus_physiol1.32447394
48MP0002098_abnormal_vibrissa_morphology1.32019893
49MP0003122_maternal_imprinting1.31589206
50MP0002909_abnormal_adrenal_gland1.30938714
51MP0004811_abnormal_neuron_physiology1.30515013
52MP0010678_abnormal_skin_adnexa1.29666495
53MP0002064_seizures1.29372548
54MP0000383_abnormal_hair_follicle1.28627187
55MP0002282_abnormal_trachea_morphology1.28308353
56MP0002572_abnormal_emotion/affect_behav1.28203661
57MP0003115_abnormal_respiratory_system1.26165407
58MP0004381_abnormal_hair_follicle1.25836310
59MP0008569_lethality_at_weaning1.25625434
60MP0000015_abnormal_ear_pigmentation1.25536659
61MP0005171_absent_coat_pigmentation1.25047582
62MP0001501_abnormal_sleep_pattern1.24500970
63MP0002132_abnormal_respiratory_system1.24393422
64MP0002735_abnormal_chemical_nociception1.24001906
65MP0002932_abnormal_joint_morphology1.22820774
66MP0002210_abnormal_sex_determination1.22752241
67MP0002896_abnormal_bone_mineralization1.22613892
68MP0002272_abnormal_nervous_system1.21632032
69MP0002161_abnormal_fertility/fecundity1.20786959
70MP0004043_abnormal_pH_regulation1.20158016
71MP0004233_abnormal_muscle_weight1.19564398
72MP0001664_abnormal_digestion1.18622518
73MP0004858_abnormal_nervous_system1.16958229
74MP0003121_genomic_imprinting1.16174198
75MP0002928_abnormal_bile_duct1.15362205
76MP0001849_ear_inflammation1.15341135
77MP0001765_abnormal_ion_homeostasis1.14953615
78MP0002882_abnormal_neuron_morphology1.11274963
79MP0000955_abnormal_spinal_cord1.11202697
80MP0003861_abnormal_nervous_system1.10535050
81MP0005423_abnormal_somatic_nervous1.10302073
82MP0002152_abnormal_brain_morphology1.10245416
83MP0002557_abnormal_social/conspecific_i1.09267246
84MP0003942_abnormal_urinary_system1.09127802
85MP0003634_abnormal_glial_cell1.09070192
86MP0000049_abnormal_middle_ear1.08473600
87MP0001968_abnormal_touch/_nociception1.06869048
88MP0001346_abnormal_lacrimal_gland1.06585147
89MP0001970_abnormal_pain_threshold1.06176733
90MP0003183_abnormal_peptide_metabolism1.03603608
91MP0009046_muscle_twitch1.03169715
92MP0000537_abnormal_urethra_morphology1.00426047
93MP0002067_abnormal_sensory_capabilities1.00146991
94MP0001502_abnormal_circadian_rhythm0.99093854
95MP0000467_abnormal_esophagus_morphology0.98585511
96MP0000579_abnormal_nail_morphology0.98583711
97MP0001958_emphysema0.96646402
98MP0000427_abnormal_hair_cycle0.96006971
99MP0002752_abnormal_somatic_nervous0.95126976
100MP0003938_abnormal_ear_development0.94526859
101MP0002168_other_aberrant_phenotype0.94445946
102MP0005503_abnormal_tendon_morphology0.93597178
103MP0005058_abnormal_lysosome_morphology0.92440472
104MP0000631_abnormal_neuroendocrine_gland0.92060648
105MP0001299_abnormal_eye_distance/0.89845049
106MP0009053_abnormal_anal_canal0.89295172
107MP0009384_cardiac_valve_regurgitation0.88414761
108MP0001293_anophthalmia0.87313321
109MP0005408_hypopigmentation0.86794332
110MP0001145_abnormal_male_reproductive0.86226329
111MP0003880_abnormal_central_pattern0.84868414
112MP0002160_abnormal_reproductive_system0.84323903
113MP0003091_abnormal_cell_migration0.83834850
114MP0001440_abnormal_grooming_behavior0.83826886
115MP0004019_abnormal_vitamin_homeostasis0.83785300
116MP0010030_abnormal_orbit_morphology0.83042331
117MP0004133_heterotaxia0.79872987
118MP0002116_abnormal_craniofacial_bone0.79509866
119MP0002249_abnormal_larynx_morphology0.78957323
120MP0002733_abnormal_thermal_nociception0.78227054
121MP0000653_abnormal_sex_gland0.77221563
122MP0005499_abnormal_olfactory_system0.76371059
123MP0005394_taste/olfaction_phenotype0.76371059
124MP0002229_neurodegeneration0.75071947
125MP0001270_distended_abdomen0.74501255
126MP0000428_abnormal_craniofacial_morphol0.74081156
127MP0002734_abnormal_mechanical_nocicepti0.72309328
128MP0002638_abnormal_pupillary_reflex0.70726867
129MP0005646_abnormal_pituitary_gland0.70039097
130MP0005508_abnormal_skeleton_morphology0.67909330
131MP0002066_abnormal_motor_capabilities/c0.67503707
132MP0005670_abnormal_white_adipose0.67332580
133MP0003941_abnormal_skin_development0.67236864
134MP0003045_fibrosis0.67036201
135MP0004134_abnormal_chest_morphology0.66211248
136MP0004742_abnormal_vestibular_system0.65100465
137MP0002092_abnormal_eye_morphology0.64711295
138MP0008770_decreased_survivor_rate0.64408071
139MP0009703_decreased_birth_body0.62361207
140MP0005195_abnormal_posterior_eye0.62287384
141MP0003123_paternal_imprinting0.61892799
142MP0002697_abnormal_eye_size0.60455998
143MP0001340_abnormal_eyelid_morphology0.60073678
144MP0005551_abnormal_eye_electrophysiolog0.59260050
145MP0001943_abnormal_respiration0.58864138
146MP0002822_catalepsy0.56377280
147MP0008789_abnormal_olfactory_epithelium0.56280229
148MP0002081_perinatal_lethality0.56176343
149MP0004145_abnormal_muscle_electrophysio0.55984979

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)5.38661553
2Absent/shortened dynein arms (HP:0200106)5.38661553
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.82294493
4Aplasia/Hypoplasia of the pubic bone (HP:0009104)4.36868982
5Abnormal respiratory motile cilium physiology (HP:0012261)3.95927794
6Mixed hearing impairment (HP:0000410)3.94480085
7Abnormal respiratory epithelium morphology (HP:0012253)3.71727855
8Abnormal respiratory motile cilium morphology (HP:0005938)3.71727855
9Abnormality of the pubic bones (HP:0003172)3.59583801
10Molar tooth sign on MRI (HP:0002419)3.48847473
11Abnormality of midbrain morphology (HP:0002418)3.48847473
12Atelectasis (HP:0100750)3.45086943
13Anomalous pulmonary venous return (HP:0010772)3.43116387
14Nephronophthisis (HP:0000090)3.42617662
15Abnormal ciliary motility (HP:0012262)3.37649424
16Male infertility (HP:0003251)3.33404679
17Hypoplastic ischia (HP:0003175)3.31124387
18Abnormality of the lower motor neuron (HP:0002366)3.28109623
19Bilateral microphthalmos (HP:0007633)3.26569833
20Rhinitis (HP:0012384)3.19555199
21Bell-shaped thorax (HP:0001591)3.08515565
22Obstructive sleep apnea (HP:0002870)3.04984428
23Humeroradial synostosis (HP:0003041)3.01975711
24Synostosis involving the elbow (HP:0003938)3.01975711
25Abnormality of the renal medulla (HP:0100957)3.01823704
26Chronic bronchitis (HP:0004469)3.01753929
27Abnormality of the pulmonary veins (HP:0011718)2.97623313
28Oligodactyly (HP:0012165)2.92765451
29Epiphyseal dysplasia (HP:0002656)2.86342430
30Hyperacusis (HP:0010780)2.85062972
31Abnormality of the ischium (HP:0003174)2.81600150
32Abnormality of the intervertebral disk (HP:0005108)2.76704042
33Heterotopia (HP:0002282)2.74742932
34Infertility (HP:0000789)2.52993009
35Upper limb amyotrophy (HP:0009129)2.51899665
36Distal upper limb amyotrophy (HP:0007149)2.51899665
37Nasal polyposis (HP:0100582)2.51670991
38Unilateral renal agenesis (HP:0000122)2.46758494
39Renal dysplasia (HP:0000110)2.42476085
40Vertebral arch anomaly (HP:0008438)2.41116920
41Short nail (HP:0001799)2.39535313
42Elfin facies (HP:0004428)2.35274665
43Neoplasm of the heart (HP:0100544)2.32067972
44Absent epiphyses (HP:0010577)2.28200558
45Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)2.28200558
46Renovascular hypertension (HP:0100817)2.21509412
47Thin bony cortex (HP:0002753)2.17093880
48Insomnia (HP:0100785)2.16993444
49Absent frontal sinuses (HP:0002688)2.16110234
50Broad face (HP:0000283)2.15770438
51Abnormal vertebral ossification (HP:0100569)2.14348463
52Cystic liver disease (HP:0006706)2.11564364
53Chronic sinusitis (HP:0011109)2.10834513
54Tubulointerstitial nephritis (HP:0001970)2.09141622
55Renal duplication (HP:0000075)2.03980976
56Occipital encephalocele (HP:0002085)2.03780511
57Morphological abnormality of the middle ear (HP:0008609)2.02147275
58Flat acetabular roof (HP:0003180)1.99703816
59Bifid tongue (HP:0010297)1.97885781
60Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.96816095
61Stridor (HP:0010307)1.96640911
62Bronchiectasis (HP:0002110)1.96096080
63Short thorax (HP:0010306)1.94387276
64Distal lower limb muscle weakness (HP:0009053)1.92639243
65Cerebral aneurysm (HP:0004944)1.92583535
66Abnormality of the distal phalanges of the toes (HP:0010182)1.92029315
67Focal seizures (HP:0007359)1.91994332
68Myokymia (HP:0002411)1.91042054
69Meningocele (HP:0002435)1.90703463
70Supranuclear gaze palsy (HP:0000605)1.90443481
71Ectopic anus (HP:0004397)1.90089703
72Spina bifida occulta (HP:0003298)1.89998303
73Abnormality of the nasal mucosa (HP:0000433)1.89500442
74Tubular atrophy (HP:0000092)1.89190651
75Hyperactive renin-angiotensin system (HP:0000841)1.89152058
76Arterial tortuosity (HP:0005116)1.88482455
77Omphalocele (HP:0001539)1.87241903
78Cervical subluxation (HP:0003308)1.84837227
79Midline defect of the nose (HP:0004122)1.84739479
80Chronic hepatic failure (HP:0100626)1.84080423
81Recurrent sinusitis (HP:0011108)1.82424173
82Cerebral inclusion bodies (HP:0100314)1.80318908
83Hyperkalemia (HP:0002153)1.77275384
84Abnormality of the aortic arch (HP:0012303)1.77095685
85Overriding aorta (HP:0002623)1.76642781
86Broad ribs (HP:0000885)1.75944535
87Bronchomalacia (HP:0002780)1.74988548
88Pancreatic fibrosis (HP:0100732)1.74987880
89Rhizomelia (HP:0008905)1.74184916
90Short ribs (HP:0000773)1.73264224
91Neurofibrillary tangles (HP:0002185)1.72980665
92Focal motor seizures (HP:0011153)1.71765200
93Bronchitis (HP:0012387)1.71711106
94Increased nuchal translucency (HP:0010880)1.70799217
95Long toe (HP:0010511)1.70231744
96Germ cell neoplasia (HP:0100728)1.70113478
97Abnormality of dentin (HP:0010299)1.69916342
98Macroorchidism (HP:0000053)1.69883661
99Genetic anticipation (HP:0003743)1.69079545
100Down-sloping shoulders (HP:0200021)1.67845163
101Polycystic kidney dysplasia (HP:0000113)1.66082426
102True hermaphroditism (HP:0010459)1.65669734
103J-shaped sella turcica (HP:0002680)1.65144473
104Vertebral clefting (HP:0008428)1.64886253
105Hand muscle atrophy (HP:0009130)1.64289029
106Narrow forehead (HP:0000341)1.64225773
107Abnormality of the humeroradial joint (HP:0100744)1.64208438
108Febrile seizures (HP:0002373)1.63780696
109Aplasia of the phalanges of the hand (HP:0009802)1.63664966
110Aplasia involving bones of the extremities (HP:0009825)1.63664966
111Aplasia involving bones of the upper limbs (HP:0009823)1.63664966
112Ocular albinism (HP:0001107)1.63343108
113Pointed chin (HP:0000307)1.62633028
114Absent eyelashes (HP:0000561)1.60001993
115Turricephaly (HP:0000262)1.58641098
116Papillary thyroid carcinoma (HP:0002895)1.58575203
117Oculomotor apraxia (HP:0000657)1.58552607
118Vascular tortuosity (HP:0004948)1.58079310
119Obsessive-compulsive behavior (HP:0000722)1.57795802
120Abnormality of the diencephalon (HP:0010662)1.56677121
121Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.55757522
122Spinal cord compression (HP:0002176)1.55143844
123Stage 5 chronic kidney disease (HP:0003774)1.54844505
124Flattened epiphyses (HP:0003071)1.54017119
125Anterior segment dysgenesis (HP:0007700)1.53640753
126Hypoplastic nipples (HP:0002557)1.53517255
127Exostoses (HP:0100777)1.53325673
128Akinesia (HP:0002304)1.52517448
129Hemiparesis (HP:0001269)1.51898500
130Hyperthyroidism (HP:0000836)1.51518347
131Recurrent otitis media (HP:0000403)1.50613838
132Impaired vibration sensation in the lower limbs (HP:0002166)1.50153583
133Atonic seizures (HP:0010819)1.49122970
134Taurodontia (HP:0000679)1.48946128
135Abnormality of permanent molar morphology (HP:0011071)1.48946128
136Abnormality of the dental root (HP:0006486)1.48946128
137Abnormality of oral frenula (HP:0000190)1.48932929
138Abnormality of molar morphology (HP:0011070)1.48898109
139Abnormality of molar (HP:0011077)1.48898109
140Congenital sensorineural hearing impairment (HP:0008527)1.48802616
141Arnold-Chiari malformation (HP:0002308)1.48749914
142Trigonocephaly (HP:0000243)1.48375545
143Ulnar bowing (HP:0003031)1.47172761
144Severe visual impairment (HP:0001141)1.46769616
145Ankle clonus (HP:0011448)1.46188677
146Nuclear cataract (HP:0100018)1.43309302
147Sleep apnea (HP:0010535)1.42326900
148Congenital glaucoma (HP:0001087)1.42251059
149Shallow orbits (HP:0000586)1.40481564
150Cone-rod dystrophy (HP:0000548)1.39586834
151Hyperparathyroidism (HP:0000843)1.39293607
152Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.39248590
153Abnormality of the dental pulp (HP:0006479)1.34834184
154Renal salt wasting (HP:0000127)1.34566545
155Abnormality of the frontal sinuses (HP:0002687)1.34078821
156Mitral stenosis (HP:0001718)1.33378114
157Deformed sella turcica (HP:0002681)1.32953878
158Postaxial foot polydactyly (HP:0001830)1.32483670
159Short femoral neck (HP:0100864)1.32357299
160Interstitial pulmonary disease (HP:0006530)1.32096906
161Broad distal phalanx of finger (HP:0009836)1.32016130
162Intellectual disability, moderate (HP:0002342)1.31725262
163Narrow chest (HP:0000774)1.31321236
164Congenital hepatic fibrosis (HP:0002612)1.30521744
165Iris hypopigmentation (HP:0007730)1.28462146

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR26.07550347
2EPHA23.91132957
3ICK3.46165611
4SIK23.44281625
5PRKD33.34185147
6MAPK152.89502134
7MST1R2.78033178
8PDK42.26008087
9PDK32.26008087
10TESK12.24538069
11PNCK2.07012378
12NTRK22.04299703
13SMG11.99745925
14SIK31.97876807
15DYRK1B1.93265762
16CAMK1G1.86992654
17TRIB31.81682200
18NTRK31.79548340
19MAP3K101.75161976
20DAPK21.74940689
21MAP3K41.69916865
22UHMK11.69721806
23SIK11.60036145
24WNK41.57902258
25PTK2B1.52827578
26MET1.51177038
27MAPKAPK31.49589081
28STK381.46931631
29WNK11.42640610
30NEK61.42084839
31EEF2K1.41137877
32EPHB11.41121430
33MAP3K91.29628656
34TYRO31.28166192
35PDPK11.24794570
36RIPK11.23957958
37ERN11.23346062
38MARK21.13986630
39LATS21.13682656
40PRKCH1.10522776
41MAP3K21.10355257
42MINK11.09389068
43PAK61.08377339
44MARK11.07894219
45BRD41.05238000
46TAOK11.04832152
47CDK61.02958171
48NEK20.96938769
49ERBB30.95716496
50FGFR30.92188473
51CDK50.87817740
52PDK20.87320669
53PKN20.82959687
54CAMKK10.82801492
55MAP3K70.82403379
56PDGFRA0.80593904
57EPHB20.80543428
58DAPK10.80453192
59MAP3K30.80205017
60PRKCI0.79017648
61NTRK10.78173412
62MAP2K20.75076408
63INSRR0.74273705
64MARK30.72625674
65LATS10.72608013
66LRRK20.72143007
67KSR10.70803193
68MUSK0.70520312
69STK30.69699724
70SGK30.69204986
71ERBB20.68982757
72RPS6KA20.68501939
73MAP2K40.68416249
74MTOR0.68340644
75CDK120.66602509
76PTK60.65754363
77LMTK20.64478692
78HIPK20.63276098
79EPHA30.62032119
80FER0.61574970
81MAP2K70.60184045
82RET0.59804686
83PAK30.59673143
84FGFR10.57776774
85MAP3K110.57316502
86STK110.56324993
87TNK20.56245147
88PAK20.54940288
89TNIK0.54466773
90KSR20.54156607
91PDGFRB0.53646867
92PRKD20.53275766
93RIPK40.52000844
94PDK10.51478698
95MAP2K10.51449239
96STK390.51265781
97IRAK20.50689656
98ROCK10.49351016
99STK160.48917460
100ABL20.48912868
101CDC42BPA0.47503487
102MAP3K60.46993979
103SGK20.45066072
104PRKCG0.44059848
105PRKCZ0.43830269
106PHKG10.43487301
107PHKG20.43487301
108PRKD10.42926572
109CAMK2G0.42759554
110PRPF4B0.42646591
111EPHA40.42402496
112CAMK1D0.41880326
113CHUK0.41321789
114MAPK80.40989952
115IRAK30.39925778
116FGFR40.39669200
117ALK0.39128836
118YES10.38607065
119SGK10.38365281
120ROCK20.37860680
121CSK0.37828014
122BMX0.37782691
123MAP3K130.37689294
124ZAP700.36745450
125PRKG20.36488335
126PTK20.36067889
127FYN0.35932536
128PAK40.35821334
129FES0.34561164
130DMPK0.34409967
131GSK3B0.34200657
132RPS6KA30.34008532
133SGK2230.33872191
134SGK4940.33872191
135CSNK1A1L0.33032090
136MAP4K10.32786217
137MAPK100.31947696
138MAPK130.31402428
139CAMK10.31051343
140RPS6KA10.30771389
141CASK0.30558100
142RPS6KL10.30435880
143RPS6KC10.30435880

Predicted pathways (KEGG)

RankGene SetZ-score
1Other types of O-glycan biosynthesis_Homo sapiens_hsa005142.83931877
2Olfactory transduction_Homo sapiens_hsa047402.17605090
3Notch signaling pathway_Homo sapiens_hsa043302.12920246
4Dorso-ventral axis formation_Homo sapiens_hsa043202.08793030
5Amphetamine addiction_Homo sapiens_hsa050311.74915343
6Insulin secretion_Homo sapiens_hsa049111.68409403
7Circadian entrainment_Homo sapiens_hsa047131.60360544
8Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.58514339
9Synaptic vesicle cycle_Homo sapiens_hsa047211.57798275
10Basal cell carcinoma_Homo sapiens_hsa052171.57646048
11Cocaine addiction_Homo sapiens_hsa050301.56663649
12Phenylalanine metabolism_Homo sapiens_hsa003601.54778627
13Long-term potentiation_Homo sapiens_hsa047201.54142875
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.52195652
15Estrogen signaling pathway_Homo sapiens_hsa049151.51289922
16Aldosterone synthesis and secretion_Homo sapiens_hsa049251.51000691
17Dopaminergic synapse_Homo sapiens_hsa047281.47527466
18Type II diabetes mellitus_Homo sapiens_hsa049301.44232144
19Histidine metabolism_Homo sapiens_hsa003401.43284130
20Phosphatidylinositol signaling system_Homo sapiens_hsa040701.42026036
21Taste transduction_Homo sapiens_hsa047421.41569655
22Carbohydrate digestion and absorption_Homo sapiens_hsa049731.40508839
23Nicotine addiction_Homo sapiens_hsa050331.39530430
24Glutamatergic synapse_Homo sapiens_hsa047241.35515945
25Cholinergic synapse_Homo sapiens_hsa047251.34631203
26Gastric acid secretion_Homo sapiens_hsa049711.30539177
27Axon guidance_Homo sapiens_hsa043601.30057860
28Melanogenesis_Homo sapiens_hsa049161.28175688
29Hippo signaling pathway_Homo sapiens_hsa043901.26874204
30Glucagon signaling pathway_Homo sapiens_hsa049221.25960324
31Morphine addiction_Homo sapiens_hsa050321.25548084
32Glycosaminoglycan degradation_Homo sapiens_hsa005311.25047131
33Fatty acid biosynthesis_Homo sapiens_hsa000611.21516739
34Chronic myeloid leukemia_Homo sapiens_hsa052201.21352656
35ErbB signaling pathway_Homo sapiens_hsa040121.19278995
36Glioma_Homo sapiens_hsa052141.18570512
37Renin secretion_Homo sapiens_hsa049241.18020482
38Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.17891363
39Thyroid hormone signaling pathway_Homo sapiens_hsa049191.17153286
40GABAergic synapse_Homo sapiens_hsa047271.12939316
41Wnt signaling pathway_Homo sapiens_hsa043101.12306921
42Tight junction_Homo sapiens_hsa045301.09952781
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.08914407
44Salivary secretion_Homo sapiens_hsa049701.07842996
45Colorectal cancer_Homo sapiens_hsa052101.07520115
46Inositol phosphate metabolism_Homo sapiens_hsa005621.06852863
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.06771666
48Sphingolipid metabolism_Homo sapiens_hsa006001.06256100
49Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.06058310
50Tyrosine metabolism_Homo sapiens_hsa003501.05477321
51GnRH signaling pathway_Homo sapiens_hsa049121.04658909
52Neurotrophin signaling pathway_Homo sapiens_hsa047221.03404970
53Calcium signaling pathway_Homo sapiens_hsa040201.01138105
54Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.99879538
55Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.99651421
56ABC transporters_Homo sapiens_hsa020100.98836225
57Lysine degradation_Homo sapiens_hsa003100.98776662
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.98757352
59Bile secretion_Homo sapiens_hsa049760.96229386
60Endometrial cancer_Homo sapiens_hsa052130.95669970
61cAMP signaling pathway_Homo sapiens_hsa040240.94635051
62Oxytocin signaling pathway_Homo sapiens_hsa049210.92125196
63mTOR signaling pathway_Homo sapiens_hsa041500.90478246
64cGMP-PKG signaling pathway_Homo sapiens_hsa040220.90266245
65Long-term depression_Homo sapiens_hsa047300.89858889
66Vibrio cholerae infection_Homo sapiens_hsa051100.89756401
67Phospholipase D signaling pathway_Homo sapiens_hsa040720.89004351
68Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88557197
69Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.87873503
70Renal cell carcinoma_Homo sapiens_hsa052110.87309786
71beta-Alanine metabolism_Homo sapiens_hsa004100.87189964
72Hedgehog signaling pathway_Homo sapiens_hsa043400.86817724
73Thyroid hormone synthesis_Homo sapiens_hsa049180.86063348
74Endocytosis_Homo sapiens_hsa041440.86029338
75Gap junction_Homo sapiens_hsa045400.85528462
76VEGF signaling pathway_Homo sapiens_hsa043700.85265330
77Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.84508533
78Other glycan degradation_Homo sapiens_hsa005110.83211514
79Longevity regulating pathway - mammal_Homo sapiens_hsa042110.83152026
80Choline metabolism in cancer_Homo sapiens_hsa052310.82629668
81Lysosome_Homo sapiens_hsa041420.82228258
82Protein digestion and absorption_Homo sapiens_hsa049740.81923383
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.81791203
84Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.81095627
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.80760528
86AMPK signaling pathway_Homo sapiens_hsa041520.79154244
87Adipocytokine signaling pathway_Homo sapiens_hsa049200.78897550
88Oocyte meiosis_Homo sapiens_hsa041140.78689119
89Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.78484639
90MAPK signaling pathway_Homo sapiens_hsa040100.78429078
91Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.78079136
92Insulin signaling pathway_Homo sapiens_hsa049100.78068652
93Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.76833997
94Rap1 signaling pathway_Homo sapiens_hsa040150.75234903
95Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73127877
96Serotonergic synapse_Homo sapiens_hsa047260.72626471
97Proteoglycans in cancer_Homo sapiens_hsa052050.72007295
98Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.71657476
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69742438
100Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.68289243
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.68145706
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.67783279
103Non-small cell lung cancer_Homo sapiens_hsa052230.67727476
104Pancreatic secretion_Homo sapiens_hsa049720.67165316
105mRNA surveillance pathway_Homo sapiens_hsa030150.66655179
106Chemical carcinogenesis_Homo sapiens_hsa052040.65338174
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.65176273
108Focal adhesion_Homo sapiens_hsa045100.63994664
109Adherens junction_Homo sapiens_hsa045200.63910211
110B cell receptor signaling pathway_Homo sapiens_hsa046620.63695232
111Leukocyte transendothelial migration_Homo sapiens_hsa046700.62893066
112T cell receptor signaling pathway_Homo sapiens_hsa046600.62679981
113Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.61745805
114Hepatitis C_Homo sapiens_hsa051600.61665412
115Insulin resistance_Homo sapiens_hsa049310.61528516
116Pancreatic cancer_Homo sapiens_hsa052120.60857243
117Prostate cancer_Homo sapiens_hsa052150.59005740
118Ras signaling pathway_Homo sapiens_hsa040140.58581588
119Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57994646
120Bladder cancer_Homo sapiens_hsa052190.57911158
121AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.57802932
122Prion diseases_Homo sapiens_hsa050200.57729262
123Vascular smooth muscle contraction_Homo sapiens_hsa042700.56145127
124ECM-receptor interaction_Homo sapiens_hsa045120.55828158
125Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.55591162
126Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53310704
127Prolactin signaling pathway_Homo sapiens_hsa049170.52438239
128Alcoholism_Homo sapiens_hsa050340.52409308
129Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.52355748
130Dilated cardiomyopathy_Homo sapiens_hsa054140.51567885

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