Rank | Gene Set | Z-score |
---|---|---|
1 | axoneme assembly (GO:0035082) | 8.92082666 |
2 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 8.19188789 |
3 | motile cilium assembly (GO:0044458) | 7.95441438 |
4 | GTP biosynthetic process (GO:0006183) | 7.86912327 |
5 | ventricular system development (GO:0021591) | 7.44756190 |
6 | nucleoside diphosphate phosphorylation (GO:0006165) | 7.39213692 |
7 | piRNA metabolic process (GO:0034587) | 7.13255915 |
8 | UTP biosynthetic process (GO:0006228) | 6.98428203 |
9 | fusion of sperm to egg plasma membrane (GO:0007342) | 6.36396381 |
10 | UTP metabolic process (GO:0046051) | 6.19354192 |
11 | guanosine-containing compound biosynthetic process (GO:1901070) | 5.97583683 |
12 | sperm motility (GO:0030317) | 5.92873127 |
13 | left/right axis specification (GO:0070986) | 5.79585269 |
14 | male meiosis (GO:0007140) | 5.71920790 |
15 | regulation of cilium movement (GO:0003352) | 5.61063624 |
16 | multicellular organism reproduction (GO:0032504) | 5.49940710 |
17 | synaptonemal complex organization (GO:0070193) | 5.49229369 |
18 | DNA methylation involved in gamete generation (GO:0043046) | 5.48343766 |
19 | acrosome assembly (GO:0001675) | 5.46555933 |
20 | sperm-egg recognition (GO:0035036) | 5.37745229 |
21 | spermatid development (GO:0007286) | 5.34689252 |
22 | intraciliary transport (GO:0042073) | 5.31400576 |
23 | CTP biosynthetic process (GO:0006241) | 5.19682329 |
24 | CTP metabolic process (GO:0046036) | 5.19682329 |
25 | male meiosis I (GO:0007141) | 5.09021544 |
26 | binding of sperm to zona pellucida (GO:0007339) | 5.08420528 |
27 | synaptonemal complex assembly (GO:0007130) | 5.06279673 |
28 | cilium organization (GO:0044782) | 4.83419140 |
29 | plasma membrane fusion (GO:0045026) | 4.80253644 |
30 | acrosome reaction (GO:0007340) | 4.74394795 |
31 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 4.72609305 |
32 | cell-cell recognition (GO:0009988) | 4.62004290 |
33 | cilium assembly (GO:0042384) | 4.59127852 |
34 | microtubule bundle formation (GO:0001578) | 4.43826202 |
35 | cilium morphogenesis (GO:0060271) | 4.43800370 |
36 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 4.39474376 |
37 | meiotic cell cycle (GO:0051321) | 4.39068451 |
38 | meiosis I (GO:0007127) | 4.36050349 |
39 | negative regulation of inclusion body assembly (GO:0090084) | 4.33041746 |
40 | single fertilization (GO:0007338) | 4.28842934 |
41 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 4.27417478 |
42 | reproduction (GO:0000003) | 4.26383197 |
43 | nucleotide phosphorylation (GO:0046939) | 4.21917852 |
44 | microtubule depolymerization (GO:0007019) | 4.20642318 |
45 | cell wall macromolecule catabolic process (GO:0016998) | 4.20111379 |
46 | cell wall macromolecule metabolic process (GO:0044036) | 4.20111379 |
47 | nonmotile primary cilium assembly (GO:0035058) | 4.08717218 |
48 | primary alcohol catabolic process (GO:0034310) | 4.00805769 |
49 | protein localization to cilium (GO:0061512) | 3.99543583 |
50 | vitamin transmembrane transport (GO:0035461) | 3.99082980 |
51 | meiotic nuclear division (GO:0007126) | 3.92559585 |
52 | cellular component assembly involved in morphogenesis (GO:0010927) | 3.91020516 |
53 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.84774375 |
54 | microtubule-based movement (GO:0007018) | 3.81410159 |
55 | fertilization (GO:0009566) | 3.76571374 |
56 | chromosome organization involved in meiosis (GO:0070192) | 3.76366450 |
57 | centriole replication (GO:0007099) | 3.75246421 |
58 | regulation of inclusion body assembly (GO:0090083) | 3.67680930 |
59 | nucleoside diphosphate metabolic process (GO:0009132) | 3.63283307 |
60 | spermatogenesis (GO:0007283) | 3.57625398 |
61 | male gamete generation (GO:0048232) | 3.57349498 |
62 | cellular response to ATP (GO:0071318) | 3.53104659 |
63 | centriole assembly (GO:0098534) | 3.52828108 |
64 | response to xenobiotic stimulus (GO:0009410) | 3.47169920 |
65 | microtubule severing (GO:0051013) | 3.46295814 |
66 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.46254443 |
67 | diterpenoid biosynthetic process (GO:0016102) | 3.41029359 |
68 | behavioral response to nicotine (GO:0035095) | 3.40818260 |
69 | one-carbon compound transport (GO:0019755) | 3.40240344 |
70 | gamete generation (GO:0007276) | 3.37708276 |
71 | cornea development in camera-type eye (GO:0061303) | 3.36191747 |
72 | protein polyglutamylation (GO:0018095) | 3.33877432 |
73 | deoxyribonucleoside diphosphate metabolic process (GO:0009186) | 3.33278709 |
74 | regulation of microtubule-based movement (GO:0060632) | 3.32045439 |
75 | regulation of meiosis I (GO:0060631) | 3.23336937 |
76 | germ cell development (GO:0007281) | 3.18796493 |
77 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.18717804 |
78 | retinal rod cell development (GO:0046548) | 3.17857242 |
79 | smoothened signaling pathway (GO:0007224) | 3.12732136 |
80 | ethanol metabolic process (GO:0006067) | 3.12183268 |
81 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 3.09682622 |
82 | determination of bilateral symmetry (GO:0009855) | 3.09029734 |
83 | regulation of germinal center formation (GO:0002634) | 3.07667577 |
84 | lateral ventricle development (GO:0021670) | 3.07628506 |
85 | cell projection assembly (GO:0030031) | 3.07399183 |
86 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.05651543 |
87 | negative regulation of B cell mediated immunity (GO:0002713) | 3.05651543 |
88 | regulation of RNA export from nucleus (GO:0046831) | 3.02166669 |
89 | specification of symmetry (GO:0009799) | 3.00269683 |
90 | otic vesicle formation (GO:0030916) | 2.95727435 |
91 | cellular process involved in reproduction in multicellular organism (GO:0022412) | 2.94824768 |
92 | spermatid nucleus differentiation (GO:0007289) | 2.94814951 |
93 | lung epithelium development (GO:0060428) | 2.92567018 |
94 | sperm capacitation (GO:0048240) | 2.92145915 |
95 | glomerular epithelial cell development (GO:0072310) | 2.90018092 |
96 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 2.88925653 |
97 | glutathione derivative metabolic process (GO:1901685) | 2.88228012 |
98 | glutathione derivative biosynthetic process (GO:1901687) | 2.88228012 |
99 | spinal cord motor neuron differentiation (GO:0021522) | 2.84061433 |
100 | exogenous drug catabolic process (GO:0042738) | 2.83641105 |
101 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.83431639 |
102 | photoreceptor cell maintenance (GO:0045494) | 2.82892798 |
103 | blastocyst development (GO:0001824) | 2.82717737 |
104 | cytoplasmic microtubule organization (GO:0031122) | 2.82599548 |
105 | retinoic acid metabolic process (GO:0042573) | 2.82107423 |
106 | chaperone-mediated protein complex assembly (GO:0051131) | 2.80695643 |
107 | retinal cone cell development (GO:0046549) | 2.80675186 |
108 | detection of light stimulus involved in visual perception (GO:0050908) | 2.79730338 |
109 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.79730338 |
110 | pyrimidine nucleotide biosynthetic process (GO:0006221) | 2.79432394 |
111 | left/right pattern formation (GO:0060972) | 2.78656054 |
112 | photoreceptor cell development (GO:0042461) | 2.76745778 |
113 | meiotic cell cycle process (GO:1903046) | 2.76690015 |
114 | tolerance induction (GO:0002507) | 2.75932921 |
115 | regulation of spindle checkpoint (GO:0090231) | 2.73315867 |
116 | terpenoid biosynthetic process (GO:0016114) | 2.71971292 |
117 | nucleotide transmembrane transport (GO:1901679) | 2.69034635 |
118 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.68099888 |
119 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.65846330 |
120 | neural tube formation (GO:0001841) | 2.64241546 |
121 | regulation of centriole replication (GO:0046599) | 2.63468482 |
122 | eye photoreceptor cell development (GO:0042462) | 2.63156778 |
123 | rRNA methylation (GO:0031167) | 2.63130388 |
124 | regulation of collateral sprouting (GO:0048670) | 2.62157724 |
125 | DNA alkylation (GO:0006305) | 2.61313810 |
126 | DNA methylation (GO:0006306) | 2.61313810 |
127 | intra-S DNA damage checkpoint (GO:0031573) | 2.61050842 |
128 | retinol metabolic process (GO:0042572) | 2.61044396 |
129 | multicellular organismal reproductive process (GO:0048609) | 2.60877784 |
130 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.60237182 |
131 | establishment of monopolar cell polarity (GO:0061162) | 2.60237182 |
132 | sialylation (GO:0097503) | 2.58183877 |
133 | organelle assembly (GO:0070925) | 2.58168272 |
134 | microtubule polymerization or depolymerization (GO:0031109) | 2.58114923 |
135 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.55137225 |
136 | determination of left/right symmetry (GO:0007368) | 2.54761147 |
137 | drug catabolic process (GO:0042737) | 2.54689848 |
138 | organic cation transport (GO:0015695) | 2.52883832 |
139 | microtubule-based process (GO:0007017) | 2.50176615 |
140 | histone exchange (GO:0043486) | 2.48158714 |
141 | cell recognition (GO:0008037) | 2.48141250 |
142 | establishment of apical/basal cell polarity (GO:0035089) | 2.47882523 |
143 | axon ensheathment in central nervous system (GO:0032291) | 2.47025940 |
144 | aldehyde catabolic process (GO:0046185) | 2.45242292 |
145 | regulation of skeletal muscle contraction (GO:0014819) | 2.38947282 |
146 | establishment of planar polarity (GO:0001736) | 2.31635965 |
147 | establishment of tissue polarity (GO:0007164) | 2.31635965 |
148 | lateral sprouting from an epithelium (GO:0060601) | 2.30844709 |
149 | rRNA modification (GO:0000154) | 2.29826219 |
150 | phosphatidylethanolamine biosynthetic process (GO:0006646) | 2.28540358 |
151 | regulation of interleukin-5 production (GO:0032674) | 2.28269146 |
152 | phosphatidylethanolamine metabolic process (GO:0046337) | 2.27062523 |
153 | neurotransmitter metabolic process (GO:0042133) | 2.25962650 |
154 | cellular ketone body metabolic process (GO:0046950) | 2.22265451 |
155 | primary alcohol metabolic process (GO:0034308) | 2.18298358 |
156 | benzene-containing compound metabolic process (GO:0042537) | 2.17616099 |
157 | GPI anchor metabolic process (GO:0006505) | 2.17072843 |
158 | cilium or flagellum-dependent cell motility (GO:0001539) | 12.6276560 |
159 | cilium movement (GO:0003341) | 11.8599742 |
160 | axonemal dynein complex assembly (GO:0070286) | 11.7085052 |
161 | epithelial cilium movement (GO:0003351) | 10.2692611 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 5.80925123 |
2 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 4.56807148 |
3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 3.10109884 |
4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.85044738 |
5 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.81498008 |
6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.51323372 |
7 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.45589919 |
8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.42905538 |
9 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.37225527 |
10 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.31900289 |
11 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.29852008 |
12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.28513683 |
13 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.13261754 |
14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.13164865 |
15 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.06654990 |
16 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 2.03891552 |
17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.91854084 |
18 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.85760925 |
19 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.84920816 |
20 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.83793296 |
21 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.83558148 |
22 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.82324989 |
23 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.79002556 |
24 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.75598157 |
25 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.73889594 |
26 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.72645457 |
27 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.69312046 |
28 | FUS_26573619_Chip-Seq_HEK293_Human | 1.68661449 |
29 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.68394810 |
30 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.64283717 |
31 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.64009455 |
32 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.63230308 |
33 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.60962418 |
34 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.59954734 |
35 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.57814346 |
36 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.57781350 |
37 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.57458963 |
38 | * ER_23166858_ChIP-Seq_MCF-7_Human | 1.51853290 |
39 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.50097355 |
40 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.47182030 |
41 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.47182030 |
42 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.46383136 |
43 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.46383136 |
44 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.45966106 |
45 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.44664301 |
46 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.44577562 |
47 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.43580564 |
48 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.43531614 |
49 | STAT3_23295773_ChIP-Seq_U87_Human | 1.41373737 |
50 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.41233412 |
51 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.39872918 |
52 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.38105238 |
53 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.36761185 |
54 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.35567440 |
55 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.35031955 |
56 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.34563418 |
57 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.34563418 |
58 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.33457511 |
59 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.32728726 |
60 | NCOR_22424771_ChIP-Seq_293T_Human | 1.31974293 |
61 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.31737002 |
62 | P300_19829295_ChIP-Seq_ESCs_Human | 1.30890685 |
63 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27882435 |
64 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.27784122 |
65 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.26934987 |
66 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26744419 |
67 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.26381900 |
68 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.26293398 |
69 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.25752685 |
70 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.25513184 |
71 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.25129542 |
72 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.24733745 |
73 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.24646857 |
74 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.24036937 |
75 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.23016198 |
76 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.22096179 |
77 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.21527537 |
78 | * PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.21141140 |
79 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.19764982 |
80 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.19619227 |
81 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.19582641 |
82 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.19430343 |
83 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.18730372 |
84 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.18639804 |
85 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.18184767 |
86 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.18023728 |
87 | ERA_21632823_ChIP-Seq_H3396_Human | 1.17324084 |
88 | AR_20517297_ChIP-Seq_VCAP_Human | 1.17245822 |
89 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.15884580 |
90 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.15524608 |
91 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.15150043 |
92 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.14393681 |
93 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.14231148 |
94 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.14095970 |
95 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.14016458 |
96 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.13974471 |
97 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.12706336 |
98 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.12563475 |
99 | TCF4_23295773_ChIP-Seq_U87_Human | 1.12559332 |
100 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.12374375 |
101 | AR_25329375_ChIP-Seq_VCAP_Human | 1.11828777 |
102 | * TAF2_19829295_ChIP-Seq_ESCs_Human | 1.11577113 |
103 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.11336363 |
104 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.10784642 |
105 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.10553043 |
106 | STAT1_17558387_ChIP-Seq_HELA_Human | 1.09372017 |
107 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09025032 |
108 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09025032 |
109 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.08890082 |
110 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.08766205 |
111 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.08106814 |
112 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.07919854 |
113 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.07878494 |
114 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.07817439 |
115 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.07775518 |
116 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.07322788 |
117 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.06805308 |
118 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.06712904 |
119 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.06329080 |
120 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 1.05914528 |
121 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.05814843 |
122 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.05601363 |
123 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.04890944 |
124 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.04396221 |
125 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.04302592 |
126 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.03985226 |
127 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.03905311 |
128 | EWS_26573619_Chip-Seq_HEK293_Human | 1.03695660 |
129 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.03480910 |
130 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.02886984 |
131 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.02811944 |
132 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.02411478 |
133 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.02113897 |
134 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.01927894 |
135 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.01592409 |
136 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.01142333 |
137 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.01061433 |
138 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.01035443 |
139 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.00980314 |
140 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.00832498 |
141 | KDM2B_26808549_Chip-Seq_REH_Human | 1.00786835 |
142 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.00302021 |
143 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.00239053 |
144 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.99764665 |
145 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.99563078 |
146 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.99226693 |
147 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.99099504 |
148 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.99045721 |
149 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.98625911 |
150 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.96775934 |
151 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.96362569 |
152 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96094629 |
153 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.95848653 |
154 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.95691265 |
155 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.94392720 |
156 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.93768313 |
157 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.93097711 |
158 | STAT3_18555785_ChIP-Seq_MESCs_Mouse | 0.92436740 |
159 | TBL1_22424771_ChIP-Seq_293T_Human | 0.92303002 |
160 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.92289019 |
161 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.92285986 |
162 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 0.92104827 |
163 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91907916 |
164 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.91589601 |
165 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91245584 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005410_abnormal_fertilization | 6.33234672 |
2 | MP0008875_abnormal_xenobiotic_pharmacok | 4.69354009 |
3 | MP0003136_yellow_coat_color | 4.24363800 |
4 | MP0002653_abnormal_ependyma_morphology | 4.02542457 |
5 | MP0008877_abnormal_DNA_methylation | 3.90481420 |
6 | MP0003698_abnormal_male_reproductive | 3.32470182 |
7 | MP0001929_abnormal_gametogenesis | 3.24870589 |
8 | MP0004043_abnormal_pH_regulation | 3.02963810 |
9 | MP0008057_abnormal_DNA_replication | 2.86131502 |
10 | MP0005171_absent_coat_pigmentation | 2.71233734 |
11 | MP0002210_abnormal_sex_determination | 2.66062751 |
12 | MP0005174_abnormal_tail_pigmentation | 2.63126852 |
13 | MP0005646_abnormal_pituitary_gland | 2.42259640 |
14 | MP0004133_heterotaxia | 2.25315862 |
15 | MP0005551_abnormal_eye_electrophysiolog | 2.19552306 |
16 | MP0001145_abnormal_male_reproductive | 2.16894004 |
17 | MP0008058_abnormal_DNA_repair | 2.12298126 |
18 | MP0003718_maternal_effect | 2.10781089 |
19 | MP0003011_delayed_dark_adaptation | 2.05215069 |
20 | MP0005623_abnormal_meninges_morphology | 2.03325323 |
21 | MP0002735_abnormal_chemical_nociception | 1.98813810 |
22 | MP0000653_abnormal_sex_gland | 1.98112850 |
23 | MP0001502_abnormal_circadian_rhythm | 1.92927753 |
24 | MP0005423_abnormal_somatic_nervous | 1.89330788 |
25 | MP0002161_abnormal_fertility/fecundity | 1.87290921 |
26 | MP0002160_abnormal_reproductive_system | 1.79222295 |
27 | MP0001984_abnormal_olfaction | 1.77574986 |
28 | MP0002638_abnormal_pupillary_reflex | 1.77544590 |
29 | MP0003693_abnormal_embryo_hatching | 1.75033532 |
30 | MP0006292_abnormal_olfactory_placode | 1.74862032 |
31 | MP0000383_abnormal_hair_follicle | 1.67290908 |
32 | MP0003880_abnormal_central_pattern | 1.65855752 |
33 | MP0005083_abnormal_biliary_tract | 1.64700356 |
34 | MP0003950_abnormal_plasma_membrane | 1.63814206 |
35 | MP0004019_abnormal_vitamin_homeostasis | 1.59677206 |
36 | MP0005253_abnormal_eye_physiology | 1.58012957 |
37 | MP0008932_abnormal_embryonic_tissue | 1.57938758 |
38 | MP0002102_abnormal_ear_morphology | 1.54716354 |
39 | MP0008004_abnormal_stomach_pH | 1.54104029 |
40 | MP0003937_abnormal_limbs/digits/tail_de | 1.52925104 |
41 | MP0010094_abnormal_chromosome_stability | 1.52619475 |
42 | MP0001986_abnormal_taste_sensitivity | 1.52069175 |
43 | MP0003786_premature_aging | 1.49239453 |
44 | MP0002282_abnormal_trachea_morphology | 1.46462967 |
45 | MP0002909_abnormal_adrenal_gland | 1.45956815 |
46 | MP0005084_abnormal_gallbladder_morpholo | 1.42085371 |
47 | MP0003111_abnormal_nucleus_morphology | 1.38655180 |
48 | MP0002876_abnormal_thyroid_physiology | 1.38281326 |
49 | MP0010386_abnormal_urinary_bladder | 1.34988054 |
50 | MP0004742_abnormal_vestibular_system | 1.33673536 |
51 | MP0003938_abnormal_ear_development | 1.31060998 |
52 | MP0001485_abnormal_pinna_reflex | 1.28304179 |
53 | MP0005365_abnormal_bile_salt | 1.28290870 |
54 | MP0008872_abnormal_physiological_respon | 1.28009921 |
55 | MP0000631_abnormal_neuroendocrine_gland | 1.26519882 |
56 | MP0002928_abnormal_bile_duct | 1.24083725 |
57 | MP0001970_abnormal_pain_threshold | 1.23363358 |
58 | MP0006072_abnormal_retinal_apoptosis | 1.22673418 |
59 | MP0009780_abnormal_chondrocyte_physiolo | 1.21522151 |
60 | MP0000778_abnormal_nervous_system | 1.21377486 |
61 | MP0003646_muscle_fatigue | 1.20955985 |
62 | MP0001756_abnormal_urination | 1.20870448 |
63 | MP0008995_early_reproductive_senescence | 1.20515256 |
64 | MP0001293_anophthalmia | 1.19733853 |
65 | MP0003195_calcinosis | 1.18992916 |
66 | MP0002277_abnormal_respiratory_mucosa | 1.18007886 |
67 | MP0005389_reproductive_system_phenotype | 1.16837670 |
68 | MP0001188_hyperpigmentation | 1.15807136 |
69 | MP0009745_abnormal_behavioral_response | 1.15356847 |
70 | MP0004885_abnormal_endolymph | 1.14966645 |
71 | MP0001765_abnormal_ion_homeostasis | 1.13499956 |
72 | MP0008007_abnormal_cellular_replicative | 1.12877446 |
73 | MP0005391_vision/eye_phenotype | 1.11913858 |
74 | MP0001661_extended_life_span | 1.11456135 |
75 | MP0005377_hearing/vestibular/ear_phenot | 1.10734912 |
76 | MP0003878_abnormal_ear_physiology | 1.10734912 |
77 | MP0005195_abnormal_posterior_eye | 1.06952237 |
78 | MP0005394_taste/olfaction_phenotype | 1.06693356 |
79 | MP0005499_abnormal_olfactory_system | 1.06693356 |
80 | MP0000569_abnormal_digit_pigmentation | 1.04904516 |
81 | MP0005645_abnormal_hypothalamus_physiol | 1.03885830 |
82 | MP0003077_abnormal_cell_cycle | 1.01514977 |
83 | MP0000427_abnormal_hair_cycle | 1.01006194 |
84 | MP0002752_abnormal_somatic_nervous | 1.00696476 |
85 | MP0003861_abnormal_nervous_system | 1.00491839 |
86 | MP0000026_abnormal_inner_ear | 0.99313247 |
87 | MP0002272_abnormal_nervous_system | 0.95723989 |
88 | MP0002572_abnormal_emotion/affect_behav | 0.93352539 |
89 | MP0010678_abnormal_skin_adnexa | 0.92401339 |
90 | MP0005647_abnormal_sex_gland | 0.92178711 |
91 | MP0005395_other_phenotype | 0.91996571 |
92 | MP0006276_abnormal_autonomic_nervous | 0.90531607 |
93 | MP0001286_abnormal_eye_development | 0.89961084 |
94 | MP0004957_abnormal_blastocyst_morpholog | 0.89598223 |
95 | MP0003123_paternal_imprinting | 0.88715443 |
96 | MP0001963_abnormal_hearing_physiology | 0.86533285 |
97 | MP0000566_synostosis | 0.86269072 |
98 | MP0001440_abnormal_grooming_behavior | 0.85679841 |
99 | MP0002557_abnormal_social/conspecific_i | 0.85368169 |
100 | MP0001346_abnormal_lacrimal_gland | 0.84390360 |
101 | MP0009046_muscle_twitch | 0.81874371 |
102 | MP0005085_abnormal_gallbladder_physiolo | 0.81349155 |
103 | MP0000428_abnormal_craniofacial_morphol | 0.80602624 |
104 | MP0004381_abnormal_hair_follicle | 0.80554427 |
105 | MP0002152_abnormal_brain_morphology | 0.78914491 |
106 | MP0002127_abnormal_cardiovascular_syste | 0.78075424 |
107 | MP0003121_genomic_imprinting | 0.77223861 |
108 | MP0001529_abnormal_vocalization | 0.77197145 |
109 | MP0002084_abnormal_developmental_patter | 0.74592250 |
110 | MP0001119_abnormal_female_reproductive | 0.73812615 |
111 | MP0001486_abnormal_startle_reflex | 0.73763526 |
112 | MP0001919_abnormal_reproductive_system | 0.73345988 |
113 | MP0002233_abnormal_nose_morphology | 0.72443149 |
114 | MP0003634_abnormal_glial_cell | 0.72227293 |
115 | MP0004142_abnormal_muscle_tone | 0.71797349 |
116 | MP0002067_abnormal_sensory_capabilities | 0.71191039 |
117 | MP0002085_abnormal_embryonic_tissue | 0.70913618 |
118 | MP0009697_abnormal_copulation | 0.70825745 |
119 | MP0001905_abnormal_dopamine_level | 0.70748181 |
120 | MP0003699_abnormal_female_reproductive | 0.69701495 |
121 | MP0002734_abnormal_mechanical_nocicepti | 0.69189127 |
122 | MP0002229_neurodegeneration | 0.68515924 |
123 | MP0002168_other_aberrant_phenotype | 0.67457603 |
124 | MP0001851_eye_inflammation | 0.67322477 |
125 | MP0000432_abnormal_head_morphology | 0.67166199 |
126 | MP0002938_white_spotting | 0.65787610 |
127 | MP0005636_abnormal_mineral_homeostasis | 0.65321573 |
128 | MP0000049_abnormal_middle_ear | 0.64800012 |
129 | MP0008789_abnormal_olfactory_epithelium | 0.64604569 |
130 | MP0000015_abnormal_ear_pigmentation | 0.63908369 |
131 | MP0003806_abnormal_nucleotide_metabolis | 0.63147650 |
132 | MP0002882_abnormal_neuron_morphology | 0.62588897 |
133 | MP0002132_abnormal_respiratory_system | 0.62501325 |
134 | MP0000955_abnormal_spinal_cord | 0.61990071 |
135 | MP0002163_abnormal_gland_morphology | 0.61884124 |
136 | MP0001501_abnormal_sleep_pattern | 0.61878569 |
137 | MP0002736_abnormal_nociception_after | 0.60970423 |
138 | MP0001324_abnormal_eye_pigmentation | 0.60835754 |
139 | MP0001968_abnormal_touch/_nociception | 0.60534601 |
140 | MP0009250_abnormal_appendicular_skeleto | 0.60303996 |
141 | MP0003315_abnormal_perineum_morphology | 0.60246094 |
142 | MP0005167_abnormal_blood-brain_barrier | 0.60208562 |
143 | MP0003941_abnormal_skin_development | 0.60119933 |
144 | MP0001944_abnormal_pancreas_morphology | 0.59903895 |
145 | MP0009643_abnormal_urine_homeostasis | 0.59826923 |
146 | MP0002063_abnormal_learning/memory/cond | 0.59744655 |
147 | MP0009379_abnormal_foot_pigmentation | 0.58729295 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Rhinitis (HP:0012384) | 8.78607619 |
2 | Abnormal respiratory motile cilium morphology (HP:0005938) | 8.38413145 |
3 | Abnormal respiratory epithelium morphology (HP:0012253) | 8.38413145 |
4 | Absent/shortened dynein arms (HP:0200106) | 8.10238372 |
5 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 8.10238372 |
6 | Chronic bronchitis (HP:0004469) | 6.11570804 |
7 | Bronchiectasis (HP:0002110) | 4.95740236 |
8 | Pancreatic fibrosis (HP:0100732) | 4.23232469 |
9 | Supernumerary spleens (HP:0009799) | 3.95423718 |
10 | Nephronophthisis (HP:0000090) | 3.72128328 |
11 | Infertility (HP:0000789) | 3.67463594 |
12 | True hermaphroditism (HP:0010459) | 3.64086764 |
13 | Medial flaring of the eyebrow (HP:0010747) | 3.60123230 |
14 | Nasal polyposis (HP:0100582) | 3.51163266 |
15 | Congenital primary aphakia (HP:0007707) | 3.24494212 |
16 | Gait imbalance (HP:0002141) | 3.22041605 |
17 | Molar tooth sign on MRI (HP:0002419) | 3.20448911 |
18 | Abnormality of midbrain morphology (HP:0002418) | 3.20448911 |
19 | Pancreatic cysts (HP:0001737) | 3.16319566 |
20 | Recurrent sinusitis (HP:0011108) | 3.06364774 |
21 | Tubulointerstitial nephritis (HP:0001970) | 3.03808483 |
22 | Bronchitis (HP:0012387) | 2.91087918 |
23 | Abnormality of the renal medulla (HP:0100957) | 2.87405180 |
24 | Nephrogenic diabetes insipidus (HP:0009806) | 2.87091062 |
25 | Abnormality of the nasal mucosa (HP:0000433) | 2.87068052 |
26 | Postaxial foot polydactyly (HP:0001830) | 2.75606451 |
27 | Abnormal biliary tract physiology (HP:0012439) | 2.56034052 |
28 | Bile duct proliferation (HP:0001408) | 2.56034052 |
29 | Chronic otitis media (HP:0000389) | 2.54408559 |
30 | Poor coordination (HP:0002370) | 2.53197956 |
31 | Median cleft lip (HP:0000161) | 2.52340257 |
32 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.51857256 |
33 | Genital tract atresia (HP:0001827) | 2.49687082 |
34 | Congenital hepatic fibrosis (HP:0002612) | 2.45224839 |
35 | Recurrent otitis media (HP:0000403) | 2.40861684 |
36 | Occipital encephalocele (HP:0002085) | 2.37543098 |
37 | Anencephaly (HP:0002323) | 2.35581535 |
38 | Vaginal atresia (HP:0000148) | 2.33701738 |
39 | Chronic sinusitis (HP:0011109) | 2.29179653 |
40 | Cystic liver disease (HP:0006706) | 2.27421019 |
41 | Decreased circulating renin level (HP:0003351) | 2.24452950 |
42 | Facial cleft (HP:0002006) | 2.16798499 |
43 | Male pseudohermaphroditism (HP:0000037) | 2.15040206 |
44 | Sclerocornea (HP:0000647) | 2.14720709 |
45 | Postaxial hand polydactyly (HP:0001162) | 2.09808849 |
46 | Preaxial hand polydactyly (HP:0001177) | 2.08391877 |
47 | Male infertility (HP:0003251) | 2.06525900 |
48 | Abnormality of the dental root (HP:0006486) | 2.06111448 |
49 | Taurodontia (HP:0000679) | 2.06111448 |
50 | Abnormality of permanent molar morphology (HP:0011071) | 2.06111448 |
51 | Furrowed tongue (HP:0000221) | 2.05190504 |
52 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.01029861 |
53 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 11.7326459 |
54 | Abnormal respiratory motile cilium physiology (HP:0012261) | 10.5948180 |
55 | Abnormal ciliary motility (HP:0012262) | 10.0117934 |
56 | Atelectasis (HP:0100750) | 1.97555401 |
57 | Tubular atrophy (HP:0000092) | 1.97252974 |
58 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.96543087 |
59 | Impulsivity (HP:0100710) | 1.94378616 |
60 | Abnormality of molar (HP:0011077) | 1.90339204 |
61 | Abnormality of molar morphology (HP:0011070) | 1.90339204 |
62 | Abnormality of the dental pulp (HP:0006479) | 1.89570712 |
63 | Rib fusion (HP:0000902) | 1.89091624 |
64 | Adrenal hypoplasia (HP:0000835) | 1.86701912 |
65 | Fibular hypoplasia (HP:0003038) | 1.84641327 |
66 | Tubulointerstitial abnormality (HP:0001969) | 1.83518439 |
67 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.82714042 |
68 | Abnormality of dentin (HP:0010299) | 1.81979974 |
69 | Stage 5 chronic kidney disease (HP:0003774) | 1.81785607 |
70 | Absent speech (HP:0001344) | 1.80035874 |
71 | Hyperactive renin-angiotensin system (HP:0000841) | 1.77846035 |
72 | Oculomotor apraxia (HP:0000657) | 1.77660912 |
73 | Chronic hepatic failure (HP:0100626) | 1.76973293 |
74 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.76660739 |
75 | Retinitis pigmentosa (HP:0000510) | 1.75700436 |
76 | Abdominal situs inversus (HP:0003363) | 1.71418908 |
77 | Abnormality of abdominal situs (HP:0011620) | 1.71418908 |
78 | Septo-optic dysplasia (HP:0100842) | 1.68620312 |
79 | Abnormal sex determination (HP:0012244) | 1.68562512 |
80 | Sex reversal (HP:0012245) | 1.68562512 |
81 | Nephropathy (HP:0000112) | 1.68092037 |
82 | Abnormality of the labia minora (HP:0012880) | 1.65969549 |
83 | Aplasia of the musculature (HP:0100854) | 1.64449813 |
84 | Decreased central vision (HP:0007663) | 1.64070288 |
85 | Polyuria (HP:0000103) | 1.64020450 |
86 | Abnormality of macular pigmentation (HP:0008002) | 1.63796314 |
87 | Microglossia (HP:0000171) | 1.63609403 |
88 | Congenital stationary night blindness (HP:0007642) | 1.59037745 |
89 | Aganglionic megacolon (HP:0002251) | 1.58921012 |
90 | Fetal akinesia sequence (HP:0001989) | 1.54577995 |
91 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.51145860 |
92 | Asplenia (HP:0001746) | 1.51100755 |
93 | Chorioretinal atrophy (HP:0000533) | 1.49644381 |
94 | Specific learning disability (HP:0001328) | 1.48973747 |
95 | Attenuation of retinal blood vessels (HP:0007843) | 1.48692307 |
96 | Astigmatism (HP:0000483) | 1.48655365 |
97 | Hypoalbuminemia (HP:0003073) | 1.48354882 |
98 | Abnormal albumin level (HP:0012116) | 1.48354882 |
99 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.47431778 |
100 | Single umbilical artery (HP:0001195) | 1.47431778 |
101 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.47431778 |
102 | Polydipsia (HP:0001959) | 1.46418312 |
103 | Abnormal drinking behavior (HP:0030082) | 1.46418312 |
104 | Dyschromatopsia (HP:0007641) | 1.46337098 |
105 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.45254469 |
106 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.41724072 |
107 | Tubulointerstitial fibrosis (HP:0005576) | 1.41720751 |
108 | Broad foot (HP:0001769) | 1.41345937 |
109 | Abnormality of renin-angiotensin system (HP:0000847) | 1.40880050 |
110 | Recurrent bronchitis (HP:0002837) | 1.39173792 |
111 | Decreased testicular size (HP:0008734) | 1.38122875 |
112 | Abolished electroretinogram (ERG) (HP:0000550) | 1.38046015 |
113 | Absent septum pellucidum (HP:0001331) | 1.37986650 |
114 | Popliteal pterygium (HP:0009756) | 1.36778113 |
115 | Narrow forehead (HP:0000341) | 1.36559097 |
116 | Type II lissencephaly (HP:0007260) | 1.36414004 |
117 | Prominent nasal bridge (HP:0000426) | 1.36354298 |
118 | Abnormality of renal excretion (HP:0011036) | 1.35924388 |
119 | Concave nail (HP:0001598) | 1.35731377 |
120 | Abnormality of the renal cortex (HP:0011035) | 1.35639948 |
121 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.34056623 |
122 | Multicystic kidney dysplasia (HP:0000003) | 1.33670573 |
123 | Abnormality of the septum pellucidum (HP:0007375) | 1.32543960 |
124 | Abnormal urine output (HP:0012590) | 1.31695178 |
125 | Gonadotropin excess (HP:0000837) | 1.31152617 |
126 | Short ribs (HP:0000773) | 1.30821064 |
127 | Congenital malformation of the right heart (HP:0011723) | 1.29617175 |
128 | Double outlet right ventricle (HP:0001719) | 1.29617175 |
129 | Bifid tongue (HP:0010297) | 1.29354837 |
130 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.28306003 |
131 | Cone-rod dystrophy (HP:0000548) | 1.28183744 |
132 | Renal salt wasting (HP:0000127) | 1.28089047 |
133 | Optic nerve coloboma (HP:0000588) | 1.27415992 |
134 | Choroideremia (HP:0001139) | 1.25088718 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAPK15 | 5.30786884 |
2 | PNCK | 4.50887156 |
3 | PDK4 | 4.26590165 |
4 | PDK3 | 4.26590165 |
5 | FRK | 3.36137126 |
6 | PDK2 | 3.28324229 |
7 | WEE1 | 3.24616209 |
8 | INSRR | 3.19420771 |
9 | MKNK2 | 2.76957544 |
10 | STK39 | 2.34356759 |
11 | BUB1 | 2.17663805 |
12 | CASK | 2.05391116 |
13 | VRK1 | 1.93534542 |
14 | GRK1 | 1.90242332 |
15 | NEK2 | 1.90189820 |
16 | SRPK1 | 1.83705654 |
17 | MAP4K2 | 1.81579123 |
18 | PLK4 | 1.80529889 |
19 | DYRK3 | 1.63802046 |
20 | GRK7 | 1.62356766 |
21 | BRSK2 | 1.60972263 |
22 | ACVR1B | 1.59373556 |
23 | STK16 | 1.53396120 |
24 | MKNK1 | 1.53008577 |
25 | MAP3K4 | 1.46384607 |
26 | MAPKAPK3 | 1.44756974 |
27 | PINK1 | 1.43473097 |
28 | EPHA2 | 1.41232354 |
29 | PLK3 | 1.41129586 |
30 | TESK1 | 1.35963993 |
31 | NTRK2 | 1.31894311 |
32 | TTK | 1.31686577 |
33 | MST4 | 1.27545041 |
34 | ADRBK1 | 1.26628759 |
35 | AKT3 | 1.23905410 |
36 | CHEK2 | 1.22193026 |
37 | PLK1 | 1.21141605 |
38 | BMPR1B | 1.19411903 |
39 | CDK3 | 1.19059546 |
40 | WNK4 | 1.16450368 |
41 | IRAK1 | 1.13519821 |
42 | NME1 | 1.08817683 |
43 | CCNB1 | 1.07577246 |
44 | NEK6 | 1.06623482 |
45 | PTK2B | 1.05859850 |
46 | IRAK2 | 1.04680244 |
47 | STK38L | 1.03254587 |
48 | DYRK2 | 1.02010104 |
49 | ERBB3 | 1.01799269 |
50 | SIK2 | 1.01088234 |
51 | AURKA | 1.00729919 |
52 | EPHA4 | 0.94247275 |
53 | MARK1 | 0.92947097 |
54 | CDC7 | 0.91132019 |
55 | BRAF | 0.87388991 |
56 | PBK | 0.85682603 |
57 | MUSK | 0.85141647 |
58 | PKN1 | 0.82977904 |
59 | MELK | 0.81767711 |
60 | TLK1 | 0.81733841 |
61 | NUAK1 | 0.79414603 |
62 | PLK2 | 0.77829499 |
63 | STK24 | 0.77491912 |
64 | MAP2K6 | 0.73638892 |
65 | TSSK6 | 0.72764248 |
66 | STK3 | 0.68441551 |
67 | PAK3 | 0.68122738 |
68 | ERBB2 | 0.66827630 |
69 | MAPK13 | 0.66526926 |
70 | GRK5 | 0.65194699 |
71 | NLK | 0.64590108 |
72 | OXSR1 | 0.63859141 |
73 | EIF2AK1 | 0.63144504 |
74 | ICK | 0.62909765 |
75 | STK38 | 0.61506648 |
76 | CDK8 | 0.61484642 |
77 | LATS2 | 0.61453431 |
78 | BRSK1 | 0.61032280 |
79 | TYRO3 | 0.59722959 |
80 | AURKB | 0.59413025 |
81 | CDK7 | 0.59045224 |
82 | TRIM28 | 0.59020629 |
83 | ADRBK2 | 0.58874366 |
84 | YES1 | 0.58041345 |
85 | PRKCE | 0.56492190 |
86 | EIF2AK2 | 0.55288281 |
87 | PHKG2 | 0.55181028 |
88 | PHKG1 | 0.55181028 |
89 | RPS6KA5 | 0.53537764 |
90 | PRKACA | 0.51301902 |
91 | ATM | 0.50186356 |
92 | CHEK1 | 0.49762433 |
93 | PRKCQ | 0.48148590 |
94 | TNIK | 0.47861244 |
95 | CSK | 0.47751823 |
96 | BLK | 0.47481836 |
97 | GSK3A | 0.45657483 |
98 | MAP3K2 | 0.45526158 |
99 | CSNK2A1 | 0.44614900 |
100 | PRKCG | 0.43402307 |
101 | PRKAA2 | 0.43175303 |
102 | ARAF | 0.42813028 |
103 | WNK3 | 0.42402418 |
104 | STK11 | 0.41798848 |
105 | PRKG1 | 0.41047797 |
106 | SGK223 | 0.40145563 |
107 | SGK494 | 0.40145563 |
108 | TEC | 0.38254732 |
109 | DYRK1A | 0.38162695 |
110 | SGK1 | 0.38116088 |
111 | TXK | 0.38049892 |
112 | MAPKAPK5 | 0.37622559 |
113 | PRKCA | 0.37439018 |
114 | ZAK | 0.36580472 |
115 | CAMKK2 | 0.35806716 |
116 | CSNK1G2 | 0.35530152 |
117 | MARK3 | 0.35199578 |
118 | NME2 | 0.34460864 |
119 | PAK1 | 0.33850119 |
120 | EPHB2 | 0.33842281 |
121 | CSNK2A2 | 0.33540659 |
122 | MAP3K3 | 0.33196631 |
123 | TGFBR1 | 0.32922100 |
124 | CHUK | 0.31913817 |
125 | BCR | 0.30879346 |
126 | DYRK1B | 0.30831618 |
127 | ABL1 | 0.30607432 |
128 | TAOK3 | 0.30292302 |
129 | NEK9 | 0.30074199 |
130 | TIE1 | 0.29871777 |
131 | IKBKB | 0.29140439 |
132 | SGK2 | 0.28751493 |
133 | CSNK1E | 0.28147420 |
134 | CAMK2A | 0.28058700 |
135 | GRK6 | 0.28056634 |
136 | CDK2 | 0.27771283 |
137 | EPHA3 | 0.27373051 |
138 | CDK1 | 0.26667652 |
139 | MAP2K7 | 0.26025098 |
140 | CSNK1D | 0.25978052 |
141 | CDK5 | 0.25291917 |
142 | MAPK10 | 0.24768925 |
143 | TRPM7 | 0.24648298 |
144 | CSNK1A1 | 0.24157854 |
145 | NTRK3 | 0.23703862 |
146 | EIF2AK3 | 0.23101252 |
147 | FGR | 0.23083522 |
148 | ATR | 0.22530136 |
149 | AKT2 | 0.21823129 |
150 | PRKCI | 0.21535220 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 6.15740089 |
2 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.46972638 |
3 | Basal transcription factors_Homo sapiens_hsa03022 | 3.35780295 |
4 | Phototransduction_Homo sapiens_hsa04744 | 3.35421027 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 3.28823739 |
6 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 3.25613081 |
7 | Huntingtons disease_Homo sapiens_hsa05016 | 3.16857171 |
8 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 3.01483618 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 2.92690974 |
10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.83041312 |
11 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.55440908 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.28771457 |
13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.28251411 |
14 | Histidine metabolism_Homo sapiens_hsa00340 | 2.27644729 |
15 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.26445237 |
16 | Purine metabolism_Homo sapiens_hsa00230 | 2.16810621 |
17 | RNA transport_Homo sapiens_hsa03013 | 2.08908377 |
18 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.02546762 |
19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.99844245 |
20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.99534171 |
21 | Cell cycle_Homo sapiens_hsa04110 | 1.93391628 |
22 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.88021461 |
23 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.79161003 |
24 | Spliceosome_Homo sapiens_hsa03040 | 1.77608351 |
25 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.76220241 |
26 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.71873052 |
27 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.68800364 |
28 | Sulfur relay system_Homo sapiens_hsa04122 | 1.63350357 |
29 | Proteasome_Homo sapiens_hsa03050 | 1.63274016 |
30 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.59818592 |
31 | RNA degradation_Homo sapiens_hsa03018 | 1.44495270 |
32 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.43711876 |
33 | Parkinsons disease_Homo sapiens_hsa05012 | 1.41992957 |
34 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.41312692 |
35 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.40526062 |
36 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.38203835 |
37 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.30673739 |
38 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.30248961 |
39 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.28804363 |
40 | Peroxisome_Homo sapiens_hsa04146 | 1.22532413 |
41 | Protein export_Homo sapiens_hsa03060 | 1.20853376 |
42 | ABC transporters_Homo sapiens_hsa02010 | 1.18884470 |
43 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.18321496 |
44 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.17549588 |
45 | Base excision repair_Homo sapiens_hsa03410 | 1.16535768 |
46 | Mismatch repair_Homo sapiens_hsa03430 | 1.16411979 |
47 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.16397243 |
48 | DNA replication_Homo sapiens_hsa03030 | 1.13502240 |
49 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.13162525 |
50 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.11328376 |
51 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.06059721 |
52 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.05945787 |
53 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.04396614 |
54 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.00494167 |
55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.97497098 |
56 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.96119000 |
57 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.93865504 |
58 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.90842829 |
59 | Ribosome_Homo sapiens_hsa03010 | 0.90550439 |
60 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.88105822 |
61 | Salivary secretion_Homo sapiens_hsa04970 | 0.85425962 |
62 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.85222029 |
63 | Alzheimers disease_Homo sapiens_hsa05010 | 0.83791367 |
64 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.83143852 |
65 | Mineral absorption_Homo sapiens_hsa04978 | 0.81088524 |
66 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.79918333 |
67 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.79583904 |
68 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.79084517 |
69 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.74967199 |
70 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.74103744 |
71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.70785082 |
72 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.69667262 |
73 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.69665645 |
74 | Morphine addiction_Homo sapiens_hsa05032 | 0.68938893 |
75 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.68705401 |
76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.68586827 |
77 | Nicotine addiction_Homo sapiens_hsa05033 | 0.68385433 |
78 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.67045035 |
79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66804681 |
80 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.65964974 |
81 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65826951 |
82 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.65091412 |
83 | Circadian entrainment_Homo sapiens_hsa04713 | 0.64964307 |
84 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.63820056 |
85 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.63790384 |
86 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.62647419 |
87 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.61811076 |
88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60965785 |
89 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.60213301 |
90 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.58678616 |
91 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.58032822 |
92 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.57100701 |
93 | Retinol metabolism_Homo sapiens_hsa00830 | 0.56896318 |
94 | Taste transduction_Homo sapiens_hsa04742 | 0.56687696 |
95 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.56234496 |
96 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.54356427 |
97 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.54168161 |
98 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.50377501 |
99 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.50189787 |
100 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.49597274 |
101 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.49512182 |
102 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47558535 |
103 | GABAergic synapse_Homo sapiens_hsa04727 | 0.45871279 |
104 | Asthma_Homo sapiens_hsa05310 | 0.43742447 |
105 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.43622986 |
106 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.43412974 |
107 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.43157836 |
108 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.41699327 |
109 | Alcoholism_Homo sapiens_hsa05034 | 0.40497413 |
110 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.39879876 |
111 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.39767846 |
112 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.39441202 |
113 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.38904637 |
114 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.38364251 |
115 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.37937201 |
116 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.37623974 |
117 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37305763 |
118 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.36601304 |
119 | Circadian rhythm_Homo sapiens_hsa04710 | 0.36154632 |
120 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.35633305 |
121 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.35226120 |
122 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.35177726 |
123 | Insulin secretion_Homo sapiens_hsa04911 | 0.34481347 |
124 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.34157446 |
125 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.33769417 |
126 | Tight junction_Homo sapiens_hsa04530 | 0.31663286 |
127 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.31493095 |
128 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.31245703 |
129 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.31042623 |
130 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.30356296 |
131 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.30163231 |
132 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.29411894 |
133 | Axon guidance_Homo sapiens_hsa04360 | 0.28300777 |
134 | Olfactory transduction_Homo sapiens_hsa04740 | 0.25475480 |
135 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.24088210 |
136 | Cocaine addiction_Homo sapiens_hsa05030 | 0.22149705 |
137 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.21447773 |
138 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.21323677 |
139 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.19082392 |
140 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.17779589 |
141 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.16919199 |
142 | HTLV-I infection_Homo sapiens_hsa05166 | 0.16785982 |