IQCG

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axoneme assembly (GO:0035082)8.92082666
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.19188789
3motile cilium assembly (GO:0044458)7.95441438
4GTP biosynthetic process (GO:0006183)7.86912327
5ventricular system development (GO:0021591)7.44756190
6nucleoside diphosphate phosphorylation (GO:0006165)7.39213692
7piRNA metabolic process (GO:0034587)7.13255915
8UTP biosynthetic process (GO:0006228)6.98428203
9fusion of sperm to egg plasma membrane (GO:0007342)6.36396381
10UTP metabolic process (GO:0046051)6.19354192
11guanosine-containing compound biosynthetic process (GO:1901070)5.97583683
12sperm motility (GO:0030317)5.92873127
13left/right axis specification (GO:0070986)5.79585269
14male meiosis (GO:0007140)5.71920790
15regulation of cilium movement (GO:0003352)5.61063624
16multicellular organism reproduction (GO:0032504)5.49940710
17synaptonemal complex organization (GO:0070193)5.49229369
18DNA methylation involved in gamete generation (GO:0043046)5.48343766
19acrosome assembly (GO:0001675)5.46555933
20sperm-egg recognition (GO:0035036)5.37745229
21spermatid development (GO:0007286)5.34689252
22intraciliary transport (GO:0042073)5.31400576
23CTP biosynthetic process (GO:0006241)5.19682329
24CTP metabolic process (GO:0046036)5.19682329
25male meiosis I (GO:0007141)5.09021544
26binding of sperm to zona pellucida (GO:0007339)5.08420528
27synaptonemal complex assembly (GO:0007130)5.06279673
28cilium organization (GO:0044782)4.83419140
29plasma membrane fusion (GO:0045026)4.80253644
30acrosome reaction (GO:0007340)4.74394795
31pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)4.72609305
32cell-cell recognition (GO:0009988)4.62004290
33cilium assembly (GO:0042384)4.59127852
34microtubule bundle formation (GO:0001578)4.43826202
35cilium morphogenesis (GO:0060271)4.43800370
36pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.39474376
37meiotic cell cycle (GO:0051321)4.39068451
38meiosis I (GO:0007127)4.36050349
39negative regulation of inclusion body assembly (GO:0090084)4.33041746
40single fertilization (GO:0007338)4.28842934
41pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)4.27417478
42reproduction (GO:0000003)4.26383197
43nucleotide phosphorylation (GO:0046939)4.21917852
44microtubule depolymerization (GO:0007019)4.20642318
45cell wall macromolecule catabolic process (GO:0016998)4.20111379
46cell wall macromolecule metabolic process (GO:0044036)4.20111379
47nonmotile primary cilium assembly (GO:0035058)4.08717218
48primary alcohol catabolic process (GO:0034310)4.00805769
49protein localization to cilium (GO:0061512)3.99543583
50vitamin transmembrane transport (GO:0035461)3.99082980
51meiotic nuclear division (GO:0007126)3.92559585
52cellular component assembly involved in morphogenesis (GO:0010927)3.91020516
53pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.84774375
54microtubule-based movement (GO:0007018)3.81410159
55fertilization (GO:0009566)3.76571374
56chromosome organization involved in meiosis (GO:0070192)3.76366450
57centriole replication (GO:0007099)3.75246421
58regulation of inclusion body assembly (GO:0090083)3.67680930
59nucleoside diphosphate metabolic process (GO:0009132)3.63283307
60spermatogenesis (GO:0007283)3.57625398
61male gamete generation (GO:0048232)3.57349498
62cellular response to ATP (GO:0071318)3.53104659
63centriole assembly (GO:0098534)3.52828108
64response to xenobiotic stimulus (GO:0009410)3.47169920
65microtubule severing (GO:0051013)3.46295814
66negative regulation of T cell differentiation in thymus (GO:0033085)3.46254443
67diterpenoid biosynthetic process (GO:0016102)3.41029359
68behavioral response to nicotine (GO:0035095)3.40818260
69one-carbon compound transport (GO:0019755)3.40240344
70gamete generation (GO:0007276)3.37708276
71cornea development in camera-type eye (GO:0061303)3.36191747
72protein polyglutamylation (GO:0018095)3.33877432
73deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.33278709
74regulation of microtubule-based movement (GO:0060632)3.32045439
75regulation of meiosis I (GO:0060631)3.23336937
76germ cell development (GO:0007281)3.18796493
77pyrimidine-containing compound transmembrane transport (GO:0072531)3.18717804
78retinal rod cell development (GO:0046548)3.17857242
79smoothened signaling pathway (GO:0007224)3.12732136
80ethanol metabolic process (GO:0006067)3.12183268
81pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.09682622
82determination of bilateral symmetry (GO:0009855)3.09029734
83regulation of germinal center formation (GO:0002634)3.07667577
84lateral ventricle development (GO:0021670)3.07628506
85cell projection assembly (GO:0030031)3.07399183
86negative regulation of immunoglobulin mediated immune response (GO:0002890)3.05651543
87negative regulation of B cell mediated immunity (GO:0002713)3.05651543
88regulation of RNA export from nucleus (GO:0046831)3.02166669
89specification of symmetry (GO:0009799)3.00269683
90otic vesicle formation (GO:0030916)2.95727435
91cellular process involved in reproduction in multicellular organism (GO:0022412)2.94824768
92spermatid nucleus differentiation (GO:0007289)2.94814951
93lung epithelium development (GO:0060428)2.92567018
94sperm capacitation (GO:0048240)2.92145915
95glomerular epithelial cell development (GO:0072310)2.90018092
96pyrimidine ribonucleotide biosynthetic process (GO:0009220)2.88925653
97glutathione derivative metabolic process (GO:1901685)2.88228012
98glutathione derivative biosynthetic process (GO:1901687)2.88228012
99spinal cord motor neuron differentiation (GO:0021522)2.84061433
100exogenous drug catabolic process (GO:0042738)2.83641105
101establishment of protein localization to mitochondrial membrane (GO:0090151)2.83431639
102photoreceptor cell maintenance (GO:0045494)2.82892798
103blastocyst development (GO:0001824)2.82717737
104cytoplasmic microtubule organization (GO:0031122)2.82599548
105retinoic acid metabolic process (GO:0042573)2.82107423
106chaperone-mediated protein complex assembly (GO:0051131)2.80695643
107retinal cone cell development (GO:0046549)2.80675186
108detection of light stimulus involved in visual perception (GO:0050908)2.79730338
109detection of light stimulus involved in sensory perception (GO:0050962)2.79730338
110pyrimidine nucleotide biosynthetic process (GO:0006221)2.79432394
111left/right pattern formation (GO:0060972)2.78656054
112photoreceptor cell development (GO:0042461)2.76745778
113meiotic cell cycle process (GO:1903046)2.76690015
114tolerance induction (GO:0002507)2.75932921
115regulation of spindle checkpoint (GO:0090231)2.73315867
116terpenoid biosynthetic process (GO:0016114)2.71971292
117nucleotide transmembrane transport (GO:1901679)2.69034635
118purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.68099888
119preassembly of GPI anchor in ER membrane (GO:0016254)2.65846330
120neural tube formation (GO:0001841)2.64241546
121regulation of centriole replication (GO:0046599)2.63468482
122eye photoreceptor cell development (GO:0042462)2.63156778
123rRNA methylation (GO:0031167)2.63130388
124regulation of collateral sprouting (GO:0048670)2.62157724
125DNA alkylation (GO:0006305)2.61313810
126DNA methylation (GO:0006306)2.61313810
127intra-S DNA damage checkpoint (GO:0031573)2.61050842
128retinol metabolic process (GO:0042572)2.61044396
129multicellular organismal reproductive process (GO:0048609)2.60877784
130establishment or maintenance of monopolar cell polarity (GO:0061339)2.60237182
131establishment of monopolar cell polarity (GO:0061162)2.60237182
132sialylation (GO:0097503)2.58183877
133organelle assembly (GO:0070925)2.58168272
134microtubule polymerization or depolymerization (GO:0031109)2.58114923
135purine nucleoside triphosphate biosynthetic process (GO:0009145)2.55137225
136determination of left/right symmetry (GO:0007368)2.54761147
137drug catabolic process (GO:0042737)2.54689848
138organic cation transport (GO:0015695)2.52883832
139microtubule-based process (GO:0007017)2.50176615
140histone exchange (GO:0043486)2.48158714
141cell recognition (GO:0008037)2.48141250
142establishment of apical/basal cell polarity (GO:0035089)2.47882523
143axon ensheathment in central nervous system (GO:0032291)2.47025940
144aldehyde catabolic process (GO:0046185)2.45242292
145regulation of skeletal muscle contraction (GO:0014819)2.38947282
146establishment of planar polarity (GO:0001736)2.31635965
147establishment of tissue polarity (GO:0007164)2.31635965
148lateral sprouting from an epithelium (GO:0060601)2.30844709
149rRNA modification (GO:0000154)2.29826219
150phosphatidylethanolamine biosynthetic process (GO:0006646)2.28540358
151regulation of interleukin-5 production (GO:0032674)2.28269146
152phosphatidylethanolamine metabolic process (GO:0046337)2.27062523
153neurotransmitter metabolic process (GO:0042133)2.25962650
154cellular ketone body metabolic process (GO:0046950)2.22265451
155primary alcohol metabolic process (GO:0034308)2.18298358
156benzene-containing compound metabolic process (GO:0042537)2.17616099
157GPI anchor metabolic process (GO:0006505)2.17072843
158cilium or flagellum-dependent cell motility (GO:0001539)12.6276560
159cilium movement (GO:0003341)11.8599742
160axonemal dynein complex assembly (GO:0070286)11.7085052
161epithelial cilium movement (GO:0003351)10.2692611

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.80925123
2CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.56807148
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.10109884
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.85044738
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.81498008
6FLI1_27457419_Chip-Seq_LIVER_Mouse2.51323372
7EZH2_22144423_ChIP-Seq_EOC_Human2.45589919
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.42905538
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.37225527
10DROSHA_22980978_ChIP-Seq_HELA_Human2.31900289
11PCGF2_27294783_Chip-Seq_ESCs_Mouse2.29852008
12VDR_22108803_ChIP-Seq_LS180_Human2.28513683
13RNF2_27304074_Chip-Seq_NSC_Mouse2.13261754
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.13164865
15IGF1R_20145208_ChIP-Seq_DFB_Human2.06654990
16KAP1_22055183_ChIP-Seq_ESCs_Mouse2.03891552
17GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.91854084
18GATA1_26923725_Chip-Seq_HPCs_Mouse1.85760925
19SUZ12_27294783_Chip-Seq_NPCs_Mouse1.84920816
20CBX2_27304074_Chip-Seq_ESCs_Mouse1.83793296
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.83558148
22GBX2_23144817_ChIP-Seq_PC3_Human1.82324989
23PIAS1_25552417_ChIP-Seq_VCAP_Human1.79002556
24* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.75598157
25NR3C1_21868756_ChIP-Seq_MCF10A_Human1.73889594
26NFE2_27457419_Chip-Seq_LIVER_Mouse1.72645457
27POU3F2_20337985_ChIP-ChIP_501MEL_Human1.69312046
28FUS_26573619_Chip-Seq_HEK293_Human1.68661449
29CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68394810
30TAF15_26573619_Chip-Seq_HEK293_Human1.64283717
31CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.64009455
32FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.63230308
33PCGF2_27294783_Chip-Seq_NPCs_Mouse1.60962418
34TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.59954734
35CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.57814346
36KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.57781350
37SALL1_21062744_ChIP-ChIP_HESCs_Human1.57458963
38* ER_23166858_ChIP-Seq_MCF-7_Human1.51853290
39EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.50097355
40TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.47182030
41POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.47182030
42CBP_20019798_ChIP-Seq_JUKART_Human1.46383136
43IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.46383136
44SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.45966106
45TAL1_26923725_Chip-Seq_HPCs_Mouse1.44664301
46NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.44577562
47NANOG_18555785_Chip-Seq_ESCs_Mouse1.43580564
48GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.43531614
49STAT3_23295773_ChIP-Seq_U87_Human1.41373737
50TP53_22573176_ChIP-Seq_HFKS_Human1.41233412
51RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.39872918
52TCF4_22108803_ChIP-Seq_LS180_Human1.38105238
53EZH2_27294783_Chip-Seq_NPCs_Mouse1.36761185
54SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35567440
55MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.35031955
56FOXA1_27270436_Chip-Seq_PROSTATE_Human1.34563418
57FOXA1_25329375_ChIP-Seq_VCAP_Human1.34563418
58AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.33457511
59CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.32728726
60NCOR_22424771_ChIP-Seq_293T_Human1.31974293
61CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.31737002
62P300_19829295_ChIP-Seq_ESCs_Human1.30890685
63TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.27882435
64MYC_19829295_ChIP-Seq_ESCs_Human1.27784122
65EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.26934987
66CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26744419
67STAT3_18555785_Chip-Seq_ESCs_Mouse1.26381900
68CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26293398
69P300_18555785_Chip-Seq_ESCs_Mouse1.25752685
70E2F1_18555785_Chip-Seq_ESCs_Mouse1.25513184
71P53_22387025_ChIP-Seq_ESCs_Mouse1.25129542
72* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.24733745
73TDRD3_21172665_ChIP-Seq_MCF-7_Human1.24646857
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.24036937
75POU5F1_16153702_ChIP-ChIP_HESCs_Human1.23016198
76SUZ12_18555785_Chip-Seq_ESCs_Mouse1.22096179
77BMI1_23680149_ChIP-Seq_NPCS_Mouse1.21527537
78* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21141140
79RUNX2_22187159_ChIP-Seq_PCA_Human1.19764982
80EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.19619227
81SMAD4_21741376_ChIP-Seq_EPCs_Human1.19582641
82GATA3_21878914_ChIP-Seq_MCF-7_Human1.19430343
83SMAD4_21799915_ChIP-Seq_A2780_Human1.18730372
84CRX_20693478_ChIP-Seq_RETINA_Mouse1.18639804
85OCT4_18555785_Chip-Seq_ESCs_Mouse1.18184767
86TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.18023728
87ERA_21632823_ChIP-Seq_H3396_Human1.17324084
88AR_20517297_ChIP-Seq_VCAP_Human1.17245822
89ETV1_20927104_ChIP-Seq_GIST48_Human1.15884580
90SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.15524608
91STAT6_21828071_ChIP-Seq_BEAS2B_Human1.15150043
92TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14393681
93OCT4_21477851_ChIP-Seq_ESCs_Mouse1.14231148
94SMRT_27268052_Chip-Seq_Bcells_Human1.14095970
95ZFX_18555785_Chip-Seq_ESCs_Mouse1.14016458
96CMYC_18555785_Chip-Seq_ESCs_Mouse1.13974471
97ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.12706336
98MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12563475
99TCF4_23295773_ChIP-Seq_U87_Human1.12559332
100KLF4_18555785_Chip-Seq_ESCs_Mouse1.12374375
101AR_25329375_ChIP-Seq_VCAP_Human1.11828777
102* TAF2_19829295_ChIP-Seq_ESCs_Human1.11577113
103EZH2_27294783_Chip-Seq_ESCs_Mouse1.11336363
104NANOG_20526341_ChIP-Seq_ESCs_Human1.10784642
105E2F1_20622854_ChIP-Seq_HELA_Human1.10553043
106STAT1_17558387_ChIP-Seq_HELA_Human1.09372017
107NANOG_19829295_ChIP-Seq_ESCs_Human1.09025032
108SOX2_19829295_ChIP-Seq_ESCs_Human1.09025032
109CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.08890082
110P53_21459846_ChIP-Seq_SAOS-2_Human1.08766205
111OCT4_20526341_ChIP-Seq_ESCs_Human1.08106814
112SOX2_18555785_Chip-Seq_ESCs_Mouse1.07919854
113* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07878494
114SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07817439
115REST_21632747_ChIP-Seq_MESCs_Mouse1.07775518
116RUNX1_27457419_Chip-Seq_LIVER_Mouse1.07322788
117RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.06805308
118ZNF274_21170338_ChIP-Seq_K562_Hela1.06712904
119EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.06329080
120GF1B_26923725_Chip-Seq_HPCs_Mouse1.05914528
121CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.05814843
122FOXM1_26456572_ChIP-Seq_MCF-7_Human1.05601363
123HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.04890944
124AHR_22903824_ChIP-Seq_MCF-7_Human1.04396221
125YY1_22570637_ChIP-Seq_MALME-3M_Human1.04302592
126PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03985226
127EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.03905311
128EWS_26573619_Chip-Seq_HEK293_Human1.03695660
129* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.03480910
130CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.02886984
131ESRRB_18555785_Chip-Seq_ESCs_Mouse1.02811944
132PRDM14_20953172_ChIP-Seq_ESCs_Human1.02411478
133PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.02113897
134GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.01927894
135HOXB7_26014856_ChIP-Seq_BT474_Human1.01592409
136TP53_18474530_ChIP-ChIP_U2OS_Human1.01142333
137FLI1_21867929_ChIP-Seq_TH2_Mouse1.01061433
138LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.01035443
139FOXA1_21572438_ChIP-Seq_LNCaP_Human1.00980314
140UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00832498
141KDM2B_26808549_Chip-Seq_REH_Human1.00786835
142BCAT_22108803_ChIP-Seq_LS180_Human1.00302021
143NMYC_18555785_Chip-Seq_ESCs_Mouse1.00239053
144PHF8_20622854_ChIP-Seq_HELA_Human0.99764665
145IRF1_19129219_ChIP-ChIP_H3396_Human0.99563078
146ERG_20517297_ChIP-Seq_VCAP_Human0.99226693
147SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.99099504
148ELK4_26923725_Chip-Seq_MESODERM_Mouse0.99045721
149KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98625911
150CTCF_20526341_ChIP-Seq_ESCs_Human0.96775934
151CTCF_27219007_Chip-Seq_Bcells_Human0.96362569
152RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.96094629
153TOP2B_26459242_ChIP-Seq_MCF-7_Human0.95848653
154WDR5_24793694_ChIP-Seq_LNCAP_Human0.95691265
155CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.94392720
156NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.93768313
157STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93097711
158STAT3_18555785_ChIP-Seq_MESCs_Mouse0.92436740
159TBL1_22424771_ChIP-Seq_293T_Human0.92303002
160AR_21572438_ChIP-Seq_LNCaP_Human0.92289019
161PU1_27457419_Chip-Seq_LIVER_Mouse0.92285986
162SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.92104827
163NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.91907916
164PHF8_20622853_ChIP-Seq_HELA_Human0.91589601
165LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91245584

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization6.33234672
2MP0008875_abnormal_xenobiotic_pharmacok4.69354009
3MP0003136_yellow_coat_color4.24363800
4MP0002653_abnormal_ependyma_morphology4.02542457
5MP0008877_abnormal_DNA_methylation3.90481420
6MP0003698_abnormal_male_reproductive3.32470182
7MP0001929_abnormal_gametogenesis3.24870589
8MP0004043_abnormal_pH_regulation3.02963810
9MP0008057_abnormal_DNA_replication2.86131502
10MP0005171_absent_coat_pigmentation2.71233734
11MP0002210_abnormal_sex_determination2.66062751
12MP0005174_abnormal_tail_pigmentation2.63126852
13MP0005646_abnormal_pituitary_gland2.42259640
14MP0004133_heterotaxia2.25315862
15MP0005551_abnormal_eye_electrophysiolog2.19552306
16MP0001145_abnormal_male_reproductive2.16894004
17MP0008058_abnormal_DNA_repair2.12298126
18MP0003718_maternal_effect2.10781089
19MP0003011_delayed_dark_adaptation2.05215069
20MP0005623_abnormal_meninges_morphology2.03325323
21MP0002735_abnormal_chemical_nociception1.98813810
22MP0000653_abnormal_sex_gland1.98112850
23MP0001502_abnormal_circadian_rhythm1.92927753
24MP0005423_abnormal_somatic_nervous1.89330788
25MP0002161_abnormal_fertility/fecundity1.87290921
26MP0002160_abnormal_reproductive_system1.79222295
27MP0001984_abnormal_olfaction1.77574986
28MP0002638_abnormal_pupillary_reflex1.77544590
29MP0003693_abnormal_embryo_hatching1.75033532
30MP0006292_abnormal_olfactory_placode1.74862032
31MP0000383_abnormal_hair_follicle1.67290908
32MP0003880_abnormal_central_pattern1.65855752
33MP0005083_abnormal_biliary_tract1.64700356
34MP0003950_abnormal_plasma_membrane1.63814206
35MP0004019_abnormal_vitamin_homeostasis1.59677206
36MP0005253_abnormal_eye_physiology1.58012957
37MP0008932_abnormal_embryonic_tissue1.57938758
38MP0002102_abnormal_ear_morphology1.54716354
39MP0008004_abnormal_stomach_pH1.54104029
40MP0003937_abnormal_limbs/digits/tail_de1.52925104
41MP0010094_abnormal_chromosome_stability1.52619475
42MP0001986_abnormal_taste_sensitivity1.52069175
43MP0003786_premature_aging1.49239453
44MP0002282_abnormal_trachea_morphology1.46462967
45MP0002909_abnormal_adrenal_gland1.45956815
46MP0005084_abnormal_gallbladder_morpholo1.42085371
47MP0003111_abnormal_nucleus_morphology1.38655180
48MP0002876_abnormal_thyroid_physiology1.38281326
49MP0010386_abnormal_urinary_bladder1.34988054
50MP0004742_abnormal_vestibular_system1.33673536
51MP0003938_abnormal_ear_development1.31060998
52MP0001485_abnormal_pinna_reflex1.28304179
53MP0005365_abnormal_bile_salt1.28290870
54MP0008872_abnormal_physiological_respon1.28009921
55MP0000631_abnormal_neuroendocrine_gland1.26519882
56MP0002928_abnormal_bile_duct1.24083725
57MP0001970_abnormal_pain_threshold1.23363358
58MP0006072_abnormal_retinal_apoptosis1.22673418
59MP0009780_abnormal_chondrocyte_physiolo1.21522151
60MP0000778_abnormal_nervous_system1.21377486
61MP0003646_muscle_fatigue1.20955985
62MP0001756_abnormal_urination1.20870448
63MP0008995_early_reproductive_senescence1.20515256
64MP0001293_anophthalmia1.19733853
65MP0003195_calcinosis1.18992916
66MP0002277_abnormal_respiratory_mucosa1.18007886
67MP0005389_reproductive_system_phenotype1.16837670
68MP0001188_hyperpigmentation1.15807136
69MP0009745_abnormal_behavioral_response1.15356847
70MP0004885_abnormal_endolymph1.14966645
71MP0001765_abnormal_ion_homeostasis1.13499956
72MP0008007_abnormal_cellular_replicative1.12877446
73MP0005391_vision/eye_phenotype1.11913858
74MP0001661_extended_life_span1.11456135
75MP0005377_hearing/vestibular/ear_phenot1.10734912
76MP0003878_abnormal_ear_physiology1.10734912
77MP0005195_abnormal_posterior_eye1.06952237
78MP0005394_taste/olfaction_phenotype1.06693356
79MP0005499_abnormal_olfactory_system1.06693356
80MP0000569_abnormal_digit_pigmentation1.04904516
81MP0005645_abnormal_hypothalamus_physiol1.03885830
82MP0003077_abnormal_cell_cycle1.01514977
83MP0000427_abnormal_hair_cycle1.01006194
84MP0002752_abnormal_somatic_nervous1.00696476
85MP0003861_abnormal_nervous_system1.00491839
86MP0000026_abnormal_inner_ear0.99313247
87MP0002272_abnormal_nervous_system0.95723989
88MP0002572_abnormal_emotion/affect_behav0.93352539
89MP0010678_abnormal_skin_adnexa0.92401339
90MP0005647_abnormal_sex_gland0.92178711
91MP0005395_other_phenotype0.91996571
92MP0006276_abnormal_autonomic_nervous0.90531607
93MP0001286_abnormal_eye_development0.89961084
94MP0004957_abnormal_blastocyst_morpholog0.89598223
95MP0003123_paternal_imprinting0.88715443
96MP0001963_abnormal_hearing_physiology0.86533285
97MP0000566_synostosis0.86269072
98MP0001440_abnormal_grooming_behavior0.85679841
99MP0002557_abnormal_social/conspecific_i0.85368169
100MP0001346_abnormal_lacrimal_gland0.84390360
101MP0009046_muscle_twitch0.81874371
102MP0005085_abnormal_gallbladder_physiolo0.81349155
103MP0000428_abnormal_craniofacial_morphol0.80602624
104MP0004381_abnormal_hair_follicle0.80554427
105MP0002152_abnormal_brain_morphology0.78914491
106MP0002127_abnormal_cardiovascular_syste0.78075424
107MP0003121_genomic_imprinting0.77223861
108MP0001529_abnormal_vocalization0.77197145
109MP0002084_abnormal_developmental_patter0.74592250
110MP0001119_abnormal_female_reproductive0.73812615
111MP0001486_abnormal_startle_reflex0.73763526
112MP0001919_abnormal_reproductive_system0.73345988
113MP0002233_abnormal_nose_morphology0.72443149
114MP0003634_abnormal_glial_cell0.72227293
115MP0004142_abnormal_muscle_tone0.71797349
116MP0002067_abnormal_sensory_capabilities0.71191039
117MP0002085_abnormal_embryonic_tissue0.70913618
118MP0009697_abnormal_copulation0.70825745
119MP0001905_abnormal_dopamine_level0.70748181
120MP0003699_abnormal_female_reproductive0.69701495
121MP0002734_abnormal_mechanical_nocicepti0.69189127
122MP0002229_neurodegeneration0.68515924
123MP0002168_other_aberrant_phenotype0.67457603
124MP0001851_eye_inflammation0.67322477
125MP0000432_abnormal_head_morphology0.67166199
126MP0002938_white_spotting0.65787610
127MP0005636_abnormal_mineral_homeostasis0.65321573
128MP0000049_abnormal_middle_ear0.64800012
129MP0008789_abnormal_olfactory_epithelium0.64604569
130MP0000015_abnormal_ear_pigmentation0.63908369
131MP0003806_abnormal_nucleotide_metabolis0.63147650
132MP0002882_abnormal_neuron_morphology0.62588897
133MP0002132_abnormal_respiratory_system0.62501325
134MP0000955_abnormal_spinal_cord0.61990071
135MP0002163_abnormal_gland_morphology0.61884124
136MP0001501_abnormal_sleep_pattern0.61878569
137MP0002736_abnormal_nociception_after0.60970423
138MP0001324_abnormal_eye_pigmentation0.60835754
139MP0001968_abnormal_touch/_nociception0.60534601
140MP0009250_abnormal_appendicular_skeleto0.60303996
141MP0003315_abnormal_perineum_morphology0.60246094
142MP0005167_abnormal_blood-brain_barrier0.60208562
143MP0003941_abnormal_skin_development0.60119933
144MP0001944_abnormal_pancreas_morphology0.59903895
145MP0009643_abnormal_urine_homeostasis0.59826923
146MP0002063_abnormal_learning/memory/cond0.59744655
147MP0009379_abnormal_foot_pigmentation0.58729295

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)8.78607619
2Abnormal respiratory motile cilium morphology (HP:0005938)8.38413145
3Abnormal respiratory epithelium morphology (HP:0012253)8.38413145
4Absent/shortened dynein arms (HP:0200106)8.10238372
5Dynein arm defect of respiratory motile cilia (HP:0012255)8.10238372
6Chronic bronchitis (HP:0004469)6.11570804
7Bronchiectasis (HP:0002110)4.95740236
8Pancreatic fibrosis (HP:0100732)4.23232469
9Supernumerary spleens (HP:0009799)3.95423718
10Nephronophthisis (HP:0000090)3.72128328
11Infertility (HP:0000789)3.67463594
12True hermaphroditism (HP:0010459)3.64086764
13Medial flaring of the eyebrow (HP:0010747)3.60123230
14Nasal polyposis (HP:0100582)3.51163266
15Congenital primary aphakia (HP:0007707)3.24494212
16Gait imbalance (HP:0002141)3.22041605
17Molar tooth sign on MRI (HP:0002419)3.20448911
18Abnormality of midbrain morphology (HP:0002418)3.20448911
19Pancreatic cysts (HP:0001737)3.16319566
20Recurrent sinusitis (HP:0011108)3.06364774
21Tubulointerstitial nephritis (HP:0001970)3.03808483
22Bronchitis (HP:0012387)2.91087918
23Abnormality of the renal medulla (HP:0100957)2.87405180
24Nephrogenic diabetes insipidus (HP:0009806)2.87091062
25Abnormality of the nasal mucosa (HP:0000433)2.87068052
26Postaxial foot polydactyly (HP:0001830)2.75606451
27Abnormal biliary tract physiology (HP:0012439)2.56034052
28Bile duct proliferation (HP:0001408)2.56034052
29Chronic otitis media (HP:0000389)2.54408559
30Poor coordination (HP:0002370)2.53197956
31Median cleft lip (HP:0000161)2.52340257
32Aplasia/Hypoplasia of the tongue (HP:0010295)2.51857256
33Genital tract atresia (HP:0001827)2.49687082
34Congenital hepatic fibrosis (HP:0002612)2.45224839
35Recurrent otitis media (HP:0000403)2.40861684
36Occipital encephalocele (HP:0002085)2.37543098
37Anencephaly (HP:0002323)2.35581535
38Vaginal atresia (HP:0000148)2.33701738
39Chronic sinusitis (HP:0011109)2.29179653
40Cystic liver disease (HP:0006706)2.27421019
41Decreased circulating renin level (HP:0003351)2.24452950
42Facial cleft (HP:0002006)2.16798499
43Male pseudohermaphroditism (HP:0000037)2.15040206
44Sclerocornea (HP:0000647)2.14720709
45Postaxial hand polydactyly (HP:0001162)2.09808849
46Preaxial hand polydactyly (HP:0001177)2.08391877
47Male infertility (HP:0003251)2.06525900
48Abnormality of the dental root (HP:0006486)2.06111448
49Taurodontia (HP:0000679)2.06111448
50Abnormality of permanent molar morphology (HP:0011071)2.06111448
51Furrowed tongue (HP:0000221)2.05190504
52Abnormal rod and cone electroretinograms (HP:0008323)2.01029861
53Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.7326459
54Abnormal respiratory motile cilium physiology (HP:0012261)10.5948180
55Abnormal ciliary motility (HP:0012262)10.0117934
56Atelectasis (HP:0100750)1.97555401
57Tubular atrophy (HP:0000092)1.97252974
58Aplasia/Hypoplasia of the lens (HP:0008063)1.96543087
59Impulsivity (HP:0100710)1.94378616
60Abnormality of molar (HP:0011077)1.90339204
61Abnormality of molar morphology (HP:0011070)1.90339204
62Abnormality of the dental pulp (HP:0006479)1.89570712
63Rib fusion (HP:0000902)1.89091624
64Adrenal hypoplasia (HP:0000835)1.86701912
65Fibular hypoplasia (HP:0003038)1.84641327
66Tubulointerstitial abnormality (HP:0001969)1.83518439
67Bony spicule pigmentary retinopathy (HP:0007737)1.82714042
68Abnormality of dentin (HP:0010299)1.81979974
69Stage 5 chronic kidney disease (HP:0003774)1.81785607
70Absent speech (HP:0001344)1.80035874
71Hyperactive renin-angiotensin system (HP:0000841)1.77846035
72Oculomotor apraxia (HP:0000657)1.77660912
73Chronic hepatic failure (HP:0100626)1.76973293
74Absent rod-and cone-mediated responses on ERG (HP:0007688)1.76660739
75Retinitis pigmentosa (HP:0000510)1.75700436
76Abdominal situs inversus (HP:0003363)1.71418908
77Abnormality of abdominal situs (HP:0011620)1.71418908
78Septo-optic dysplasia (HP:0100842)1.68620312
79Abnormal sex determination (HP:0012244)1.68562512
80Sex reversal (HP:0012245)1.68562512
81Nephropathy (HP:0000112)1.68092037
82Abnormality of the labia minora (HP:0012880)1.65969549
83Aplasia of the musculature (HP:0100854)1.64449813
84Decreased central vision (HP:0007663)1.64070288
85Polyuria (HP:0000103)1.64020450
86Abnormality of macular pigmentation (HP:0008002)1.63796314
87Microglossia (HP:0000171)1.63609403
88Congenital stationary night blindness (HP:0007642)1.59037745
89Aganglionic megacolon (HP:0002251)1.58921012
90Fetal akinesia sequence (HP:0001989)1.54577995
91Hypoplasia of the capital femoral epiphysis (HP:0003090)1.51145860
92Asplenia (HP:0001746)1.51100755
93Chorioretinal atrophy (HP:0000533)1.49644381
94Specific learning disability (HP:0001328)1.48973747
95Attenuation of retinal blood vessels (HP:0007843)1.48692307
96Astigmatism (HP:0000483)1.48655365
97Hypoalbuminemia (HP:0003073)1.48354882
98Abnormal albumin level (HP:0012116)1.48354882
99Abnormal umbilical cord blood vessels (HP:0011403)1.47431778
100Single umbilical artery (HP:0001195)1.47431778
101Abnormality of the fetal cardiovascular system (HP:0010948)1.47431778
102Polydipsia (HP:0001959)1.46418312
103Abnormal drinking behavior (HP:0030082)1.46418312
104Dyschromatopsia (HP:0007641)1.46337098
105Aplasia/Hypoplasia of the spleen (HP:0010451)1.45254469
106Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.41724072
107Tubulointerstitial fibrosis (HP:0005576)1.41720751
108Broad foot (HP:0001769)1.41345937
109Abnormality of renin-angiotensin system (HP:0000847)1.40880050
110Recurrent bronchitis (HP:0002837)1.39173792
111Decreased testicular size (HP:0008734)1.38122875
112Abolished electroretinogram (ERG) (HP:0000550)1.38046015
113Absent septum pellucidum (HP:0001331)1.37986650
114Popliteal pterygium (HP:0009756)1.36778113
115Narrow forehead (HP:0000341)1.36559097
116Type II lissencephaly (HP:0007260)1.36414004
117Prominent nasal bridge (HP:0000426)1.36354298
118Abnormality of renal excretion (HP:0011036)1.35924388
119Concave nail (HP:0001598)1.35731377
120Abnormality of the renal cortex (HP:0011035)1.35639948
121Decreased electroretinogram (ERG) amplitude (HP:0000654)1.34056623
122Multicystic kidney dysplasia (HP:0000003)1.33670573
123Abnormality of the septum pellucidum (HP:0007375)1.32543960
124Abnormal urine output (HP:0012590)1.31695178
125Gonadotropin excess (HP:0000837)1.31152617
126Short ribs (HP:0000773)1.30821064
127Congenital malformation of the right heart (HP:0011723)1.29617175
128Double outlet right ventricle (HP:0001719)1.29617175
129Bifid tongue (HP:0010297)1.29354837
130Aplasia/Hypoplasia involving the musculature (HP:0001460)1.28306003
131Cone-rod dystrophy (HP:0000548)1.28183744
132Renal salt wasting (HP:0000127)1.28089047
133Optic nerve coloboma (HP:0000588)1.27415992
134Choroideremia (HP:0001139)1.25088718

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK155.30786884
2PNCK4.50887156
3PDK44.26590165
4PDK34.26590165
5FRK3.36137126
6PDK23.28324229
7WEE13.24616209
8INSRR3.19420771
9MKNK22.76957544
10STK392.34356759
11BUB12.17663805
12CASK2.05391116
13VRK11.93534542
14GRK11.90242332
15NEK21.90189820
16SRPK11.83705654
17MAP4K21.81579123
18PLK41.80529889
19DYRK31.63802046
20GRK71.62356766
21BRSK21.60972263
22ACVR1B1.59373556
23STK161.53396120
24MKNK11.53008577
25MAP3K41.46384607
26MAPKAPK31.44756974
27PINK11.43473097
28EPHA21.41232354
29PLK31.41129586
30TESK11.35963993
31NTRK21.31894311
32TTK1.31686577
33MST41.27545041
34ADRBK11.26628759
35AKT31.23905410
36CHEK21.22193026
37PLK11.21141605
38BMPR1B1.19411903
39CDK31.19059546
40WNK41.16450368
41IRAK11.13519821
42NME11.08817683
43CCNB11.07577246
44NEK61.06623482
45PTK2B1.05859850
46IRAK21.04680244
47STK38L1.03254587
48DYRK21.02010104
49ERBB31.01799269
50SIK21.01088234
51AURKA1.00729919
52EPHA40.94247275
53MARK10.92947097
54CDC70.91132019
55BRAF0.87388991
56PBK0.85682603
57MUSK0.85141647
58PKN10.82977904
59MELK0.81767711
60TLK10.81733841
61NUAK10.79414603
62PLK20.77829499
63STK240.77491912
64MAP2K60.73638892
65TSSK60.72764248
66STK30.68441551
67PAK30.68122738
68ERBB20.66827630
69MAPK130.66526926
70GRK50.65194699
71NLK0.64590108
72OXSR10.63859141
73EIF2AK10.63144504
74ICK0.62909765
75STK380.61506648
76CDK80.61484642
77LATS20.61453431
78BRSK10.61032280
79TYRO30.59722959
80AURKB0.59413025
81CDK70.59045224
82TRIM280.59020629
83ADRBK20.58874366
84YES10.58041345
85PRKCE0.56492190
86EIF2AK20.55288281
87PHKG20.55181028
88PHKG10.55181028
89RPS6KA50.53537764
90PRKACA0.51301902
91ATM0.50186356
92CHEK10.49762433
93PRKCQ0.48148590
94TNIK0.47861244
95CSK0.47751823
96BLK0.47481836
97GSK3A0.45657483
98MAP3K20.45526158
99CSNK2A10.44614900
100PRKCG0.43402307
101PRKAA20.43175303
102ARAF0.42813028
103WNK30.42402418
104STK110.41798848
105PRKG10.41047797
106SGK2230.40145563
107SGK4940.40145563
108TEC0.38254732
109DYRK1A0.38162695
110SGK10.38116088
111TXK0.38049892
112MAPKAPK50.37622559
113PRKCA0.37439018
114ZAK0.36580472
115CAMKK20.35806716
116CSNK1G20.35530152
117MARK30.35199578
118NME20.34460864
119PAK10.33850119
120EPHB20.33842281
121CSNK2A20.33540659
122MAP3K30.33196631
123TGFBR10.32922100
124CHUK0.31913817
125BCR0.30879346
126DYRK1B0.30831618
127ABL10.30607432
128TAOK30.30292302
129NEK90.30074199
130TIE10.29871777
131IKBKB0.29140439
132SGK20.28751493
133CSNK1E0.28147420
134CAMK2A0.28058700
135GRK60.28056634
136CDK20.27771283
137EPHA30.27373051
138CDK10.26667652
139MAP2K70.26025098
140CSNK1D0.25978052
141CDK50.25291917
142MAPK100.24768925
143TRPM70.24648298
144CSNK1A10.24157854
145NTRK30.23703862
146EIF2AK30.23101252
147FGR0.23083522
148ATR0.22530136
149AKT20.21823129
150PRKCI0.21535220

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007506.15740089
2Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001303.46972638
3Basal transcription factors_Homo sapiens_hsa030223.35780295
4Phototransduction_Homo sapiens_hsa047443.35421027
5RNA polymerase_Homo sapiens_hsa030203.28823739
6Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006043.25613081
7Huntingtons disease_Homo sapiens_hsa050163.16857171
8Chemical carcinogenesis_Homo sapiens_hsa052043.01483618
9Homologous recombination_Homo sapiens_hsa034402.92690974
10Fanconi anemia pathway_Homo sapiens_hsa034602.83041312
11Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.55440908
12Pyrimidine metabolism_Homo sapiens_hsa002402.28771457
13Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.28251411
14Histidine metabolism_Homo sapiens_hsa003402.27644729
15Ether lipid metabolism_Homo sapiens_hsa005652.26445237
16Purine metabolism_Homo sapiens_hsa002302.16810621
17RNA transport_Homo sapiens_hsa030132.08908377
18Nucleotide excision repair_Homo sapiens_hsa034202.02546762
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.99844245
20Linoleic acid metabolism_Homo sapiens_hsa005911.99534171
21Cell cycle_Homo sapiens_hsa041101.93391628
22Phenylalanine metabolism_Homo sapiens_hsa003601.88021461
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.79161003
24Spliceosome_Homo sapiens_hsa030401.77608351
25Caffeine metabolism_Homo sapiens_hsa002321.76220241
26beta-Alanine metabolism_Homo sapiens_hsa004101.71873052
27Oxidative phosphorylation_Homo sapiens_hsa001901.68800364
28Sulfur relay system_Homo sapiens_hsa041221.63350357
29Proteasome_Homo sapiens_hsa030501.63274016
30Tyrosine metabolism_Homo sapiens_hsa003501.59818592
31RNA degradation_Homo sapiens_hsa030181.44495270
32Oocyte meiosis_Homo sapiens_hsa041141.43711876
33Parkinsons disease_Homo sapiens_hsa050121.41992957
34Sphingolipid metabolism_Homo sapiens_hsa006001.41312692
35Steroid hormone biosynthesis_Homo sapiens_hsa001401.40526062
36Nitrogen metabolism_Homo sapiens_hsa009101.38203835
37mRNA surveillance pathway_Homo sapiens_hsa030151.30673739
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.30248961
39Arachidonic acid metabolism_Homo sapiens_hsa005901.28804363
40Peroxisome_Homo sapiens_hsa041461.22532413
41Protein export_Homo sapiens_hsa030601.20853376
42ABC transporters_Homo sapiens_hsa020101.18884470
43Primary bile acid biosynthesis_Homo sapiens_hsa001201.18321496
44Maturity onset diabetes of the young_Homo sapiens_hsa049501.17549588
45Base excision repair_Homo sapiens_hsa034101.16535768
46Mismatch repair_Homo sapiens_hsa034301.16411979
47Dorso-ventral axis formation_Homo sapiens_hsa043201.16397243
48DNA replication_Homo sapiens_hsa030301.13502240
49Glycerophospholipid metabolism_Homo sapiens_hsa005641.13162525
50Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.11328376
51Cardiac muscle contraction_Homo sapiens_hsa042601.06059721
52Butanoate metabolism_Homo sapiens_hsa006501.05945787
53Tryptophan metabolism_Homo sapiens_hsa003801.04396614
54Pyruvate metabolism_Homo sapiens_hsa006201.00494167
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.97497098
56Pentose phosphate pathway_Homo sapiens_hsa000300.96119000
57Hedgehog signaling pathway_Homo sapiens_hsa043400.93865504
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.90842829
59Ribosome_Homo sapiens_hsa030100.90550439
60Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88105822
61Salivary secretion_Homo sapiens_hsa049700.85425962
62Propanoate metabolism_Homo sapiens_hsa006400.85222029
63Alzheimers disease_Homo sapiens_hsa050100.83791367
64Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.83143852
65Mineral absorption_Homo sapiens_hsa049780.81088524
66Glutathione metabolism_Homo sapiens_hsa004800.79918333
67Fatty acid degradation_Homo sapiens_hsa000710.79583904
68Non-homologous end-joining_Homo sapiens_hsa034500.79084517
69Fatty acid elongation_Homo sapiens_hsa000620.74967199
70Intestinal immune network for IgA production_Homo sapiens_hsa046720.74103744
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.70785082
72Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.69667262
73Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.69665645
74Morphine addiction_Homo sapiens_hsa050320.68938893
75Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68705401
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.68586827
77Nicotine addiction_Homo sapiens_hsa050330.68385433
78Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67045035
79Metabolic pathways_Homo sapiens_hsa011000.66804681
80p53 signaling pathway_Homo sapiens_hsa041150.65964974
81Systemic lupus erythematosus_Homo sapiens_hsa053220.65826951
82Cysteine and methionine metabolism_Homo sapiens_hsa002700.65091412
83Circadian entrainment_Homo sapiens_hsa047130.64964307
84Glucagon signaling pathway_Homo sapiens_hsa049220.63820056
85Amphetamine addiction_Homo sapiens_hsa050310.63790384
86Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62647419
87TGF-beta signaling pathway_Homo sapiens_hsa043500.61811076
88Regulation of autophagy_Homo sapiens_hsa041400.60965785
89Epstein-Barr virus infection_Homo sapiens_hsa051690.60213301
90Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.58678616
91Basal cell carcinoma_Homo sapiens_hsa052170.58032822
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.57100701
93Retinol metabolism_Homo sapiens_hsa008300.56896318
94Taste transduction_Homo sapiens_hsa047420.56687696
95Wnt signaling pathway_Homo sapiens_hsa043100.56234496
96Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54356427
97Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54168161
98Hippo signaling pathway_Homo sapiens_hsa043900.50377501
99Vitamin digestion and absorption_Homo sapiens_hsa049770.50189787
100Arginine and proline metabolism_Homo sapiens_hsa003300.49597274
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49512182
102Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.47558535
103GABAergic synapse_Homo sapiens_hsa047270.45871279
104Asthma_Homo sapiens_hsa053100.43742447
105Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.43622986
106Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.43412974
107Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.43157836
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41699327
109Alcoholism_Homo sapiens_hsa050340.40497413
110Graft-versus-host disease_Homo sapiens_hsa053320.39879876
111Ovarian steroidogenesis_Homo sapiens_hsa049130.39767846
112Selenocompound metabolism_Homo sapiens_hsa004500.39441202
113Glycosaminoglycan degradation_Homo sapiens_hsa005310.38904637
114Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.38364251
115cAMP signaling pathway_Homo sapiens_hsa040240.37937201
116Type I diabetes mellitus_Homo sapiens_hsa049400.37623974
117Steroid biosynthesis_Homo sapiens_hsa001000.37305763
118Calcium signaling pathway_Homo sapiens_hsa040200.36601304
119Circadian rhythm_Homo sapiens_hsa047100.36154632
120Serotonergic synapse_Homo sapiens_hsa047260.35633305
121Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35226120
122Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.35177726
123Insulin secretion_Homo sapiens_hsa049110.34481347
124Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.34157446
125Collecting duct acid secretion_Homo sapiens_hsa049660.33769417
126Tight junction_Homo sapiens_hsa045300.31663286
127Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.31493095
128Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31245703
129Glutamatergic synapse_Homo sapiens_hsa047240.31042623
130Sulfur metabolism_Homo sapiens_hsa009200.30356296
131Hematopoietic cell lineage_Homo sapiens_hsa046400.30163231
132Glycerolipid metabolism_Homo sapiens_hsa005610.29411894
133Axon guidance_Homo sapiens_hsa043600.28300777
134Olfactory transduction_Homo sapiens_hsa047400.25475480
135Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.24088210
136Cocaine addiction_Homo sapiens_hsa050300.22149705
137Rheumatoid arthritis_Homo sapiens_hsa053230.21447773
138Vascular smooth muscle contraction_Homo sapiens_hsa042700.21323677
139Estrogen signaling pathway_Homo sapiens_hsa049150.19082392
140Autoimmune thyroid disease_Homo sapiens_hsa053200.17779589
141Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.16919199
142HTLV-I infection_Homo sapiens_hsa051660.16785982

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