

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 8.85556628 |
| 2 | isotype switching (GO:0045190) | 8.85556628 |
| 3 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 8.85556628 |
| 4 | sequestering of actin monomers (GO:0042989) | 7.82199122 |
| 5 | sulfur amino acid catabolic process (GO:0000098) | 6.85771773 |
| 6 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 6.28374867 |
| 7 | reciprocal DNA recombination (GO:0035825) | 6.13239203 |
| 8 | reciprocal meiotic recombination (GO:0007131) | 6.13239203 |
| 9 | mismatch repair (GO:0006298) | 6.11472223 |
| 10 | protein neddylation (GO:0045116) | 5.64575241 |
| 11 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 5.47379120 |
| 12 | somatic diversification of immunoglobulins (GO:0016445) | 5.43932080 |
| 13 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 5.31102519 |
| 14 | DNA damage response, detection of DNA damage (GO:0042769) | 5.06365430 |
| 15 | B cell activation involved in immune response (GO:0002312) | 4.90703956 |
| 16 | startle response (GO:0001964) | 4.67078610 |
| 17 | membrane hyperpolarization (GO:0060081) | 4.52602745 |
| 18 | L-methionine salvage (GO:0071267) | 4.49245725 |
| 19 | L-methionine biosynthetic process (GO:0071265) | 4.49245725 |
| 20 | amino acid salvage (GO:0043102) | 4.49245725 |
| 21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.45324486 |
| 22 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 4.42648279 |
| 23 | synaptic vesicle exocytosis (GO:0016079) | 4.17998695 |
| 24 | somatic diversification of immune receptors via germline recombination within a single locus (GO:000 | 4.16374507 |
| 25 | somatic cell DNA recombination (GO:0016444) | 4.16374507 |
| 26 | righting reflex (GO:0060013) | 4.07934767 |
| 27 | response to histamine (GO:0034776) | 3.97190190 |
| 28 | postsynaptic membrane organization (GO:0001941) | 3.85931731 |
| 29 | peroxisome fission (GO:0016559) | 3.79989209 |
| 30 | somatic diversification of immune receptors (GO:0002200) | 3.73054747 |
| 31 | protein maturation by protein folding (GO:0022417) | 3.59566980 |
| 32 | proteasome assembly (GO:0043248) | 3.58327136 |
| 33 | positive regulation of guanylate cyclase activity (GO:0031284) | 3.56280460 |
| 34 | GTP biosynthetic process (GO:0006183) | 3.53435537 |
| 35 | respiratory electron transport chain (GO:0022904) | 3.51804525 |
| 36 | behavioral response to nicotine (GO:0035095) | 3.43985266 |
| 37 | electron transport chain (GO:0022900) | 3.41201871 |
| 38 | auditory behavior (GO:0031223) | 3.34900265 |
| 39 | regulation of guanylate cyclase activity (GO:0031282) | 3.33825644 |
| 40 | positive regulation of cGMP biosynthetic process (GO:0030828) | 3.30435819 |
| 41 | cofactor catabolic process (GO:0051187) | 3.28599168 |
| 42 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.26801757 |
| 43 | chaperone-mediated protein transport (GO:0072321) | 3.25587509 |
| 44 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.21405379 |
| 45 | ATP synthesis coupled proton transport (GO:0015986) | 3.21405379 |
| 46 | regulation of cGMP biosynthetic process (GO:0030826) | 3.17614075 |
| 47 | vocalization behavior (GO:0071625) | 3.14524252 |
| 48 | UTP biosynthetic process (GO:0006228) | 3.14126366 |
| 49 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.12333795 |
| 50 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.11724317 |
| 51 | neuron cell-cell adhesion (GO:0007158) | 3.00349112 |
| 52 | anterior/posterior axis specification, embryo (GO:0008595) | 2.98527081 |
| 53 | positive regulation of cGMP metabolic process (GO:0030825) | 2.97298679 |
| 54 | protein K6-linked ubiquitination (GO:0085020) | 2.90568720 |
| 55 | presynaptic membrane assembly (GO:0097105) | 2.83164800 |
| 56 | regulation of cGMP metabolic process (GO:0030823) | 2.79757804 |
| 57 | methionine biosynthetic process (GO:0009086) | 2.79412806 |
| 58 | response to gravity (GO:0009629) | 2.74804968 |
| 59 | cilium movement (GO:0003341) | 2.72619858 |
| 60 | UTP metabolic process (GO:0046051) | 2.70328231 |
| 61 | DNA replication checkpoint (GO:0000076) | 2.69582009 |
| 62 | negative regulation of DNA metabolic process (GO:0051053) | 2.67380412 |
| 63 | myelination in peripheral nervous system (GO:0022011) | 2.65542567 |
| 64 | peripheral nervous system axon ensheathment (GO:0032292) | 2.65542567 |
| 65 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.65463887 |
| 66 | termination of RNA polymerase III transcription (GO:0006386) | 2.65463887 |
| 67 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.65444126 |
| 68 | heart contraction (GO:0060047) | 2.64690076 |
| 69 | heart process (GO:0003015) | 2.64690076 |
| 70 | sulfur amino acid metabolic process (GO:0000096) | 2.63518723 |
| 71 | entrainment of circadian clock by photoperiod (GO:0043153) | 2.60685841 |
| 72 | positive regulation of neurological system process (GO:0031646) | 2.56497623 |
| 73 | DNA integration (GO:0015074) | 2.56372283 |
| 74 | protein-cofactor linkage (GO:0018065) | 2.54647787 |
| 75 | maternal behavior (GO:0042711) | 2.54634208 |
| 76 | regulation of DNA recombination (GO:0000018) | 2.54477794 |
| 77 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.52778254 |
| 78 | epithelial cilium movement (GO:0003351) | 2.51796954 |
| 79 | coenzyme catabolic process (GO:0009109) | 2.47702439 |
| 80 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.46244056 |
| 81 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.41871867 |
| 82 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.39638403 |
| 83 | protein targeting to mitochondrion (GO:0006626) | 2.38412728 |
| 84 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.37781569 |
| 85 | positive regulation of CREB transcription factor activity (GO:0032793) | 2.36823000 |
| 86 | methionine metabolic process (GO:0006555) | 2.36193158 |
| 87 | neuronal action potential (GO:0019228) | 2.35494509 |
| 88 | regulation of timing of cell differentiation (GO:0048505) | 2.35377167 |
| 89 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 2.34755193 |
| 90 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.34236130 |
| 91 | microtubule polymerization or depolymerization (GO:0031109) | 2.33821413 |
| 92 | mechanosensory behavior (GO:0007638) | 2.33679713 |
| 93 | cerebellar Purkinje cell layer development (GO:0021680) | 2.33338886 |
| 94 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.32443158 |
| 95 | regulation of transmission of nerve impulse (GO:0051969) | 2.32440241 |
| 96 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 17.3933646 |
| 97 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 17.3933646 |
| 98 | regulation of helicase activity (GO:0051095) | 17.2063237 |
| 99 | determination of adult lifespan (GO:0008340) | 13.8100987 |
| 100 | negative regulation of DNA recombination (GO:0045910) | 10.6314234 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.53510605 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.42111794 |
| 3 | ZNF263_19887448_ChIP-Seq_K562_Human | 3.41036794 |
| 4 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.02415782 |
| 5 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.93437638 |
| 6 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.89707118 |
| 7 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.73940745 |
| 8 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.54792950 |
| 9 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.25624556 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.19756973 |
| 11 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 2.19067857 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.11558848 |
| 13 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.04414126 |
| 14 | E2F7_22180533_ChIP-Seq_HELA_Human | 11.0658656 |
| 15 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.99036851 |
| 16 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.98758010 |
| 17 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.98645537 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.92695580 |
| 19 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.91708720 |
| 20 | TP53_16413492_ChIP-PET_HCT116_Human | 1.86012200 |
| 21 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.76289789 |
| 22 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.74352323 |
| 23 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.68187519 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.68060662 |
| 25 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.66100259 |
| 26 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.65245782 |
| 27 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.57704651 |
| 28 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.55559924 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.50857238 |
| 30 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.50616009 |
| 31 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 1.49364491 |
| 32 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.47618652 |
| 33 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.47386145 |
| 34 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.46734803 |
| 35 | VDR_22108803_ChIP-Seq_LS180_Human | 1.43702604 |
| 36 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.42903712 |
| 37 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.40780677 |
| 38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.40663824 |
| 39 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.39985560 |
| 40 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.38268720 |
| 41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.36909218 |
| 42 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.30429280 |
| 43 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.26543445 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.26518379 |
| 45 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.22792871 |
| 46 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.22391251 |
| 47 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.20073877 |
| 48 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.18838958 |
| 49 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.18277619 |
| 50 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.17861917 |
| 51 | NCOR_22424771_ChIP-Seq_293T_Human | 1.13016291 |
| 52 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10388270 |
| 53 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10025219 |
| 54 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.08338812 |
| 55 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.07846400 |
| 56 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.06804688 |
| 57 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.05798725 |
| 58 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.04818808 |
| 59 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.04166568 |
| 60 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.04145224 |
| 61 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.02050260 |
| 62 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.01218532 |
| 63 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.00492446 |
| 64 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.00470257 |
| 65 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.00253396 |
| 66 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.99604929 |
| 67 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.97460637 |
| 68 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.97243884 |
| 69 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.95661058 |
| 70 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.95102967 |
| 71 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.93524984 |
| 72 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.92207911 |
| 73 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.91353692 |
| 74 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.90520525 |
| 75 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.90163382 |
| 76 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.89667134 |
| 77 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.89508607 |
| 78 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.88317698 |
| 79 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.87632657 |
| 80 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86890852 |
| 81 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.86890852 |
| 82 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.86228650 |
| 83 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.85971783 |
| 84 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.85480917 |
| 85 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.84516518 |
| 86 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.83877315 |
| 87 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.83667648 |
| 88 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.83558679 |
| 89 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.83362628 |
| 90 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.81789909 |
| 91 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.81579855 |
| 92 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.80598957 |
| 93 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.80341144 |
| 94 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.79871866 |
| 95 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.79687463 |
| 96 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.79089503 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.78912313 |
| 98 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.78840952 |
| 99 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.78649369 |
| 100 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.77955462 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004147_increased_porphyrin_level | 6.21417131 |
| 2 | MP0003566_abnormal_cell_adhesion | 4.52350179 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.94803903 |
| 4 | MP0002736_abnormal_nociception_after | 3.47208752 |
| 5 | MP0003136_yellow_coat_color | 3.11005941 |
| 6 | MP0001968_abnormal_touch/_nociception | 3.04361165 |
| 7 | MP0004859_abnormal_synaptic_plasticity | 2.56420344 |
| 8 | MP0008875_abnormal_xenobiotic_pharmacok | 2.46536785 |
| 9 | MP0004270_analgesia | 2.40076327 |
| 10 | MP0003787_abnormal_imprinting | 2.36160378 |
| 11 | MP0001529_abnormal_vocalization | 2.31169508 |
| 12 | MP0003635_abnormal_synaptic_transmissio | 2.28583218 |
| 13 | MP0009745_abnormal_behavioral_response | 2.08411813 |
| 14 | MP0001440_abnormal_grooming_behavior | 2.07175253 |
| 15 | MP0001984_abnormal_olfaction | 2.01785138 |
| 16 | MP0002909_abnormal_adrenal_gland | 1.96481041 |
| 17 | MP0005423_abnormal_somatic_nervous | 1.81261590 |
| 18 | MP0002063_abnormal_learning/memory/cond | 1.77264010 |
| 19 | MP0002734_abnormal_mechanical_nocicepti | 1.76296110 |
| 20 | MP0002572_abnormal_emotion/affect_behav | 1.73834839 |
| 21 | MP0005083_abnormal_biliary_tract | 1.73564911 |
| 22 | MP0001905_abnormal_dopamine_level | 1.69650185 |
| 23 | MP0002638_abnormal_pupillary_reflex | 1.66379498 |
| 24 | MP0006072_abnormal_retinal_apoptosis | 1.64925870 |
| 25 | MP0004811_abnormal_neuron_physiology | 1.63800684 |
| 26 | MP0000372_irregular_coat_pigmentation | 1.59612062 |
| 27 | MP0000955_abnormal_spinal_cord | 1.49606702 |
| 28 | MP0002163_abnormal_gland_morphology | 1.49595431 |
| 29 | MP0005379_endocrine/exocrine_gland_phen | 1.46708209 |
| 30 | MP0002102_abnormal_ear_morphology | 1.42825835 |
| 31 | MP0002272_abnormal_nervous_system | 1.39854573 |
| 32 | MP0003137_abnormal_impulse_conducting | 1.35564910 |
| 33 | MP0004272_abnormal_basement_membrane | 1.34034333 |
| 34 | MP0002557_abnormal_social/conspecific_i | 1.33763463 |
| 35 | MP0003880_abnormal_central_pattern | 1.32558987 |
| 36 | MP0003186_abnormal_redox_activity | 1.29056439 |
| 37 | MP0003122_maternal_imprinting | 1.28017175 |
| 38 | MP0002067_abnormal_sensory_capabilities | 1.27565056 |
| 39 | MP0004924_abnormal_behavior | 1.27101641 |
| 40 | MP0005386_behavior/neurological_phenoty | 1.27101641 |
| 41 | MP0001191_abnormal_skin_condition | 1.26429164 |
| 42 | MP0002064_seizures | 1.22413073 |
| 43 | MP0003941_abnormal_skin_development | 1.18996158 |
| 44 | MP0004145_abnormal_muscle_electrophysio | 1.18802721 |
| 45 | MP0003724_increased_susceptibility_to | 1.14752496 |
| 46 | MP0002735_abnormal_chemical_nociception | 1.14271971 |
| 47 | MP0005187_abnormal_penis_morphology | 1.12595407 |
| 48 | MP0001970_abnormal_pain_threshold | 1.09624585 |
| 49 | MP0008872_abnormal_physiological_respon | 1.09003736 |
| 50 | MP0006276_abnormal_autonomic_nervous | 1.06676042 |
| 51 | MP0000639_abnormal_adrenal_gland | 1.06664368 |
| 52 | MP0003121_genomic_imprinting | 1.05867440 |
| 53 | MP0005551_abnormal_eye_electrophysiolog | 1.01611092 |
| 54 | MP0009046_muscle_twitch | 1.00809024 |
| 55 | MP0008770_decreased_survivor_rate | 0.93704459 |
| 56 | MP0004142_abnormal_muscle_tone | 0.91856251 |
| 57 | MP0005410_abnormal_fertilization | 0.91436508 |
| 58 | MP0005332_abnormal_amino_acid | 0.91305019 |
| 59 | MP0002132_abnormal_respiratory_system | 0.90940942 |
| 60 | MP0005075_abnormal_melanosome_morpholog | 0.90203297 |
| 61 | MP0000350_abnormal_cell_proliferation | 0.88449455 |
| 62 | MP0002269_muscular_atrophy | 0.88238267 |
| 63 | MP0002751_abnormal_autonomic_nervous | 0.87760693 |
| 64 | MP0002882_abnormal_neuron_morphology | 0.87533404 |
| 65 | MP0002184_abnormal_innervation | 0.84643132 |
| 66 | MP0004215_abnormal_myocardial_fiber | 0.84273834 |
| 67 | MP0003195_calcinosis | 0.83659077 |
| 68 | MP0001486_abnormal_startle_reflex | 0.82418591 |
| 69 | MP0002233_abnormal_nose_morphology | 0.80401038 |
| 70 | MP0002332_abnormal_exercise_endurance | 0.76097399 |
| 71 | MP0002972_abnormal_cardiac_muscle | 0.75861501 |
| 72 | MP0008874_decreased_physiological_sensi | 0.75713988 |
| 73 | MP0005647_abnormal_sex_gland | 0.74867061 |
| 74 | MP0002082_postnatal_lethality | 0.74805265 |
| 75 | MP0010770_preweaning_lethality | 0.74805265 |
| 76 | MP0000579_abnormal_nail_morphology | 0.72642395 |
| 77 | MP0010769_abnormal_survival | 0.72119666 |
| 78 | MP0010768_mortality/aging | 0.71213819 |
| 79 | MP0008057_abnormal_DNA_replication | 0.69261824 |
| 80 | MP0002160_abnormal_reproductive_system | 0.68968755 |
| 81 | MP0005636_abnormal_mineral_homeostasis | 0.67755617 |
| 82 | MP0005164_abnormal_response_to | 0.66763324 |
| 83 | MP0002069_abnormal_eating/drinking_beha | 0.65013671 |
| 84 | MP0002796_impaired_skin_barrier | 0.64578782 |
| 85 | MP0002066_abnormal_motor_capabilities/c | 0.64454913 |
| 86 | MP0002837_dystrophic_cardiac_calcinosis | 0.64029829 |
| 87 | MP0005448_abnormal_energy_balance | 0.63630584 |
| 88 | MP0002090_abnormal_vision | 0.63323524 |
| 89 | MP0008995_early_reproductive_senescence | 0.63231837 |
| 90 | MP0000762_abnormal_tongue_morphology | 0.63000624 |
| 91 | MP0005389_reproductive_system_phenotype | 0.62308548 |
| 92 | MP0000750_abnormal_muscle_regeneration | 0.61993649 |
| 93 | MP0000026_abnormal_inner_ear | 0.61953257 |
| 94 | MP0002210_abnormal_sex_determination | 0.61832673 |
| 95 | MP0008058_abnormal_DNA_repair | 0.61181629 |
| 96 | MP0003385_abnormal_body_wall | 0.60762860 |
| 97 | MP0000631_abnormal_neuroendocrine_gland | 0.60704813 |
| 98 | MP0003567_abnormal_fetal_cardiomyocyte | 0.58773903 |
| 99 | MP0003755_abnormal_palate_morphology | 0.57657118 |
| 100 | MP0005253_abnormal_eye_physiology | 0.57457632 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the astrocytes (HP:0100707) | 8.73783313 |
| 2 | Astrocytoma (HP:0009592) | 8.73783313 |
| 3 | Medulloblastoma (HP:0002885) | 8.07410668 |
| 4 | Rhabdomyosarcoma (HP:0002859) | 7.83535659 |
| 5 | Biliary tract neoplasm (HP:0100574) | 6.88703219 |
| 6 | Glioma (HP:0009733) | 6.80669528 |
| 7 | Neoplasm of the oral cavity (HP:0100649) | 6.76065291 |
| 8 | Abnormality of the salivary glands (HP:0010286) | 6.24485228 |
| 9 | Angiofibromas (HP:0010615) | 5.47171445 |
| 10 | Adenoma sebaceum (HP:0009720) | 5.47171445 |
| 11 | Neoplasm of striated muscle (HP:0009728) | 5.36468099 |
| 12 | Neoplasm of the rectum (HP:0100743) | 5.09179013 |
| 13 | Amaurosis fugax (HP:0100576) | 4.96442293 |
| 14 | Basal cell carcinoma (HP:0002671) | 4.78916491 |
| 15 | Neoplasm of the small intestine (HP:0100833) | 4.44007887 |
| 16 | Neuroblastic tumors (HP:0004376) | 4.32272664 |
| 17 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 4.32272664 |
| 18 | Neuroblastoma (HP:0003006) | 4.32272664 |
| 19 | Primitive neuroectodermal tumor (HP:0030065) | 4.32272664 |
| 20 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 3.81381200 |
| 21 | Abnormal biliary tract morphology (HP:0012440) | 3.69950676 |
| 22 | Atonic seizures (HP:0010819) | 3.66356306 |
| 23 | Neoplasm of the liver (HP:0002896) | 3.39895842 |
| 24 | Freckling (HP:0001480) | 3.06878925 |
| 25 | Malignant gastrointestinal tract tumors (HP:0006749) | 3.03561528 |
| 26 | Gastrointestinal carcinoma (HP:0002672) | 3.03561528 |
| 27 | Neoplasm of the colon (HP:0100273) | 2.80725430 |
| 28 | Oral leukoplakia (HP:0002745) | 2.76780174 |
| 29 | Febrile seizures (HP:0002373) | 2.76441514 |
| 30 | Fibroma (HP:0010614) | 2.71342118 |
| 31 | Fibrous tissue neoplasm (HP:0012316) | 2.66236574 |
| 32 | Neoplasm of the respiratory system (HP:0100606) | 2.61561646 |
| 33 | Intestinal polyposis (HP:0200008) | 2.59707821 |
| 34 | Nervous tissue neoplasm (HP:0030060) | 2.54794661 |
| 35 | Neuroectodermal neoplasm (HP:0030061) | 2.54794661 |
| 36 | Neuroepithelial neoplasm (HP:0030063) | 2.54794661 |
| 37 | Malignant neoplasm of the central nervous system (HP:0100836) | 2.47690352 |
| 38 | Cerebral hypomyelination (HP:0006808) | 2.47335159 |
| 39 | Benign neoplasm of the central nervous system (HP:0100835) | 2.46353581 |
| 40 | Respiratory difficulties (HP:0002880) | 2.43437618 |
| 41 | Focal seizures (HP:0007359) | 2.42989299 |
| 42 | Intestinal polyp (HP:0005266) | 2.41222384 |
| 43 | Generalized aminoaciduria (HP:0002909) | 2.37738132 |
| 44 | Neoplasm of the thyroid gland (HP:0100031) | 2.33265791 |
| 45 | Increased hepatocellular lipid droplets (HP:0006565) | 2.30822079 |
| 46 | Neoplasm of the pancreas (HP:0002894) | 2.30607379 |
| 47 | Uterine neoplasm (HP:0010784) | 2.26157772 |
| 48 | Lipid accumulation in hepatocytes (HP:0006561) | 2.24993727 |
| 49 | Short tibia (HP:0005736) | 2.16539854 |
| 50 | Memory impairment (HP:0002354) | 2.14274132 |
| 51 | Increased intracranial pressure (HP:0002516) | 2.10866098 |
| 52 | Abnormality of intracranial pressure (HP:0012640) | 2.10866098 |
| 53 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.02152249 |
| 54 | Ovarian neoplasm (HP:0100615) | 2.01156322 |
| 55 | Focal motor seizures (HP:0011153) | 2.00353405 |
| 56 | Ependymoma (HP:0002888) | 12.2884813 |
| 57 | Agnosia (HP:0010524) | 12.2082669 |
| 58 | Supernumerary spleens (HP:0009799) | 1.96747000 |
| 59 | Absence seizures (HP:0002121) | 1.91969727 |
| 60 | Type II lissencephaly (HP:0007260) | 1.82455618 |
| 61 | Renal Fanconi syndrome (HP:0001994) | 1.82034653 |
| 62 | Ascites (HP:0001541) | 1.80868261 |
| 63 | CNS hypomyelination (HP:0003429) | 1.80520607 |
| 64 | Dialeptic seizures (HP:0011146) | 1.79354583 |
| 65 | Hypothermia (HP:0002045) | 1.79024517 |
| 66 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.78091390 |
| 67 | Hepatic necrosis (HP:0002605) | 1.73658932 |
| 68 | Cerebellar dysplasia (HP:0007033) | 1.69671350 |
| 69 | Generalized tonic-clonic seizures (HP:0002069) | 1.65432932 |
| 70 | Increased intramyocellular lipid droplets (HP:0012240) | 1.59144714 |
| 71 | Abnormal ciliary motility (HP:0012262) | 1.57572305 |
| 72 | Hypoglycemic coma (HP:0001325) | 1.56792401 |
| 73 | Abnormal lung lobation (HP:0002101) | 1.55692174 |
| 74 | Complete atrioventricular canal defect (HP:0001674) | 1.48034693 |
| 75 | Hypermelanotic macule (HP:0001034) | 1.47157040 |
| 76 | Retinal atrophy (HP:0001105) | 1.42837187 |
| 77 | Abnormality of urine glucose concentration (HP:0011016) | 1.41485174 |
| 78 | Glycosuria (HP:0003076) | 1.41485174 |
| 79 | Increased muscle lipid content (HP:0009058) | 1.39914085 |
| 80 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 1.38563462 |
| 81 | Cafe-au-lait spot (HP:0000957) | 1.37360046 |
| 82 | Absent septum pellucidum (HP:0001331) | 1.35394199 |
| 83 | Paresthesia (HP:0003401) | 1.35082142 |
| 84 | Horizontal nystagmus (HP:0000666) | 1.34056053 |
| 85 | Abnormality of the labia minora (HP:0012880) | 1.33848257 |
| 86 | Exertional dyspnea (HP:0002875) | 1.32783942 |
| 87 | Cerebral palsy (HP:0100021) | 1.31818410 |
| 88 | Nausea (HP:0002018) | 1.31118183 |
| 89 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.29527980 |
| 90 | Premature ovarian failure (HP:0008209) | 1.28680478 |
| 91 | Hepatocellular necrosis (HP:0001404) | 1.26287254 |
| 92 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.25801439 |
| 93 | Atrioventricular canal defect (HP:0006695) | 1.24863120 |
| 94 | Poor suck (HP:0002033) | 1.22295531 |
| 95 | Abnormality of the septum pellucidum (HP:0007375) | 1.21819201 |
| 96 | Increased CSF lactate (HP:0002490) | 1.20751112 |
| 97 | Mitochondrial inheritance (HP:0001427) | 1.20497154 |
| 98 | Acute necrotizing encephalopathy (HP:0006965) | 1.19265800 |
| 99 | Retinal dysplasia (HP:0007973) | 1.17860051 |
| 100 | Renal cortical cysts (HP:0000803) | 1.15924850 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 6.95487832 |
| 2 | MST4 | 2.63087926 |
| 3 | SRPK1 | 2.46117474 |
| 4 | PDK2 | 2.42424730 |
| 5 | MAPK13 | 2.35932972 |
| 6 | DAPK2 | 2.29794479 |
| 7 | TLK1 | 2.07637244 |
| 8 | PAK4 | 11.0469064 |
| 9 | ARAF | 1.93890741 |
| 10 | ACVR1B | 1.64917851 |
| 11 | MARK1 | 1.52021821 |
| 12 | CASK | 1.48328035 |
| 13 | TRIM28 | 1.29195965 |
| 14 | CSNK1D | 1.25603621 |
| 15 | BCR | 1.24324892 |
| 16 | TTK | 1.11574736 |
| 17 | PIM2 | 1.05215240 |
| 18 | MAPK12 | 1.04746091 |
| 19 | TSSK6 | 1.02256650 |
| 20 | BUB1 | 0.97163211 |
| 21 | CCNB1 | 0.95786877 |
| 22 | EIF2AK1 | 0.95410891 |
| 23 | DYRK2 | 0.94222553 |
| 24 | TESK1 | 0.93521553 |
| 25 | MAPKAPK3 | 0.91221671 |
| 26 | TESK2 | 0.88680025 |
| 27 | PHKG2 | 0.85698863 |
| 28 | PHKG1 | 0.85698863 |
| 29 | DAPK1 | 0.85148900 |
| 30 | FLT3 | 0.78745539 |
| 31 | NME1 | 0.76424267 |
| 32 | RAF1 | 0.73506705 |
| 33 | CSNK1G3 | 0.71092998 |
| 34 | SIK3 | 0.69516721 |
| 35 | DYRK3 | 0.68453108 |
| 36 | PKN1 | 0.66421370 |
| 37 | PIK3CA | 0.66351488 |
| 38 | CSF1R | 0.66097090 |
| 39 | CSNK1A1L | 0.64905203 |
| 40 | CAMK2A | 0.63363390 |
| 41 | PRKCE | 0.62545837 |
| 42 | CSNK1G1 | 0.62337870 |
| 43 | TAOK3 | 0.60995780 |
| 44 | LIMK1 | 0.59364758 |
| 45 | TNIK | 0.59355512 |
| 46 | CAMK2B | 0.58815753 |
| 47 | DAPK3 | 0.58762153 |
| 48 | DYRK1B | 0.57783249 |
| 49 | BCKDK | 0.56861493 |
| 50 | CAMK2G | 0.56607895 |
| 51 | PLK4 | 0.54942201 |
| 52 | CSNK1G2 | 0.54088044 |
| 53 | PBK | 0.51883251 |
| 54 | EIF2AK3 | 0.50911705 |
| 55 | MAP2K7 | 0.50099750 |
| 56 | WNK3 | 0.48328330 |
| 57 | BLK | 0.45329144 |
| 58 | MATK | 0.45129758 |
| 59 | EEF2K | 0.45053308 |
| 60 | CLK1 | 0.44433983 |
| 61 | MAP3K4 | 0.43302260 |
| 62 | ZAK | 0.43246349 |
| 63 | MAPK4 | 0.42335289 |
| 64 | MAPKAPK5 | 0.41978345 |
| 65 | UHMK1 | 0.41575787 |
| 66 | VRK2 | 0.41166351 |
| 67 | CSNK2A2 | 0.40960846 |
| 68 | STK16 | 0.40520579 |
| 69 | FGFR1 | 0.39754275 |
| 70 | CDK18 | 0.39478304 |
| 71 | DYRK1A | 0.39008751 |
| 72 | NME2 | 0.36864822 |
| 73 | BMPR1B | 0.35555798 |
| 74 | VRK1 | 0.34460364 |
| 75 | CDK15 | 0.34150383 |
| 76 | PASK | 0.33542976 |
| 77 | OXSR1 | 0.32425960 |
| 78 | EIF2AK2 | 0.32039330 |
| 79 | PRKCG | 0.30696749 |
| 80 | LATS2 | 0.30659980 |
| 81 | MST1R | 0.29789361 |
| 82 | MET | 0.29709279 |
| 83 | ADRBK1 | 0.28541194 |
| 84 | INSRR | 0.27659103 |
| 85 | PAK6 | 0.27453150 |
| 86 | CAMK2D | 0.26940904 |
| 87 | SIK1 | 0.26676601 |
| 88 | ERBB3 | 0.26578997 |
| 89 | RPS6KA5 | 0.26383093 |
| 90 | CDK11A | 0.26307147 |
| 91 | TGFBR1 | 0.25487195 |
| 92 | ERBB4 | 0.25225792 |
| 93 | CSNK2A1 | 0.24873124 |
| 94 | PRKG2 | 0.23646401 |
| 95 | MKNK1 | 0.22597211 |
| 96 | KSR1 | 0.22491976 |
| 97 | BMX | 0.22122373 |
| 98 | OBSCN | 0.21814958 |
| 99 | CDK14 | 0.21482629 |
| 100 | PRKAA1 | 0.21324670 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 7.58652742 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 6.50768618 |
| 3 | Nicotine addiction_Homo sapiens_hsa05033 | 3.82582155 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.14800178 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.80727765 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.67075773 |
| 7 | Taste transduction_Homo sapiens_hsa04742 | 2.13384838 |
| 8 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.07162187 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.06685229 |
| 10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.02631084 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 1.99598394 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 1.94687728 |
| 13 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.88895231 |
| 14 | Morphine addiction_Homo sapiens_hsa05032 | 1.88184616 |
| 15 | GABAergic synapse_Homo sapiens_hsa04727 | 1.83195640 |
| 16 | Phototransduction_Homo sapiens_hsa04744 | 1.73380768 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.65200713 |
| 18 | Colorectal cancer_Homo sapiens_hsa05210 | 1.62389825 |
| 19 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.55027222 |
| 20 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.49932997 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.49852018 |
| 22 | Proteasome_Homo sapiens_hsa03050 | 1.42220479 |
| 23 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.38013019 |
| 24 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.17124775 |
| 25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.10084414 |
| 26 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.09069422 |
| 27 | Axon guidance_Homo sapiens_hsa04360 | 1.06662830 |
| 28 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.04380184 |
| 29 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.00778034 |
| 30 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.99106572 |
| 31 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.94705316 |
| 32 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.92875207 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.86169283 |
| 34 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.85794433 |
| 35 | Circadian entrainment_Homo sapiens_hsa04713 | 0.80136151 |
| 36 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.78643695 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 0.76275305 |
| 38 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.75954090 |
| 39 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.71976539 |
| 40 | Basal transcription factors_Homo sapiens_hsa03022 | 0.71275704 |
| 41 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.68426854 |
| 42 | Protein export_Homo sapiens_hsa03060 | 0.67499211 |
| 43 | Spliceosome_Homo sapiens_hsa03040 | 0.66586438 |
| 44 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.64400525 |
| 45 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.62506889 |
| 46 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.60463028 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.58912849 |
| 48 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.56612524 |
| 49 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52785691 |
| 50 | Cocaine addiction_Homo sapiens_hsa05030 | 0.51131131 |
| 51 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.50403625 |
| 52 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.50213168 |
| 53 | Alcoholism_Homo sapiens_hsa05034 | 0.49413117 |
| 54 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.49300269 |
| 55 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47934385 |
| 56 | RNA transport_Homo sapiens_hsa03013 | 0.46173706 |
| 57 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.44347736 |
| 58 | Gap junction_Homo sapiens_hsa04540 | 0.43942718 |
| 59 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.43918064 |
| 60 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.40966394 |
| 61 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.40951127 |
| 62 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.39338889 |
| 63 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.38056563 |
| 64 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.37895508 |
| 65 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.37461954 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35511763 |
| 67 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.35457465 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.35102952 |
| 69 | Galactose metabolism_Homo sapiens_hsa00052 | 0.33436353 |
| 70 | Homologous recombination_Homo sapiens_hsa03440 | 0.31534353 |
| 71 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.27996729 |
| 72 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.26933550 |
| 73 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.26379056 |
| 74 | Peroxisome_Homo sapiens_hsa04146 | 0.24464978 |
| 75 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22632843 |
| 76 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.22111291 |
| 77 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.20148705 |
| 78 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.19850908 |
| 79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.19719099 |
| 80 | Legionellosis_Homo sapiens_hsa05134 | 0.19544542 |
| 81 | Olfactory transduction_Homo sapiens_hsa04740 | 0.18919958 |
| 82 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.16541797 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.15534039 |
| 84 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.15434309 |
| 85 | Salivary secretion_Homo sapiens_hsa04970 | 0.15105209 |
| 86 | Pathways in cancer_Homo sapiens_hsa05200 | 0.13535699 |
| 87 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.13051589 |
| 88 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.13016658 |
| 89 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.12984278 |
| 90 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.12807664 |
| 91 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.12155229 |
| 92 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.11975195 |
| 93 | Melanoma_Homo sapiens_hsa05218 | 0.10879729 |
| 94 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.10743961 |
| 95 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.10096788 |
| 96 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.09770274 |
| 97 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.09148416 |
| 98 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.08749947 |
| 99 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.08661153 |
| 100 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.08312701 |

