Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.10845729 |
2 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 6.10845729 |
3 | positive regulation of interferon-alpha production (GO:0032727) | 6.10629168 |
4 | regulation of interferon-alpha production (GO:0032647) | 5.79300299 |
5 | * cellular response to type I interferon (GO:0071357) | 5.77449430 |
6 | * type I interferon signaling pathway (GO:0060337) | 5.77449430 |
7 | * response to type I interferon (GO:0034340) | 5.74685492 |
8 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.73143714 |
9 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 5.40372637 |
10 | positive regulation by symbiont of host defense response (GO:0052509) | 5.29167419 |
11 | modulation by symbiont of host defense response (GO:0052031) | 5.29167419 |
12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.29167419 |
13 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.29167419 |
14 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.29167419 |
15 | modulation by symbiont of host immune response (GO:0052553) | 5.29167419 |
16 | response to interferon-alpha (GO:0035455) | 5.10414214 |
17 | regulation of chronic inflammatory response (GO:0002676) | 4.79516412 |
18 | immunoglobulin mediated immune response (GO:0016064) | 4.74713307 |
19 | response to peptidoglycan (GO:0032494) | 4.67705791 |
20 | regulation of vitamin D biosynthetic process (GO:0060556) | 4.64114575 |
21 | cellular response to virus (GO:0098586) | 4.62519164 |
22 | cellular response to interferon-alpha (GO:0035457) | 4.61963267 |
23 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.52828490 |
24 | * negative regulation of viral genome replication (GO:0045071) | 4.41551149 |
25 | interferon-gamma-mediated signaling pathway (GO:0060333) | 4.34343735 |
26 | response to interferon-beta (GO:0035456) | 4.30112784 |
27 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.27038814 |
28 | positive regulation of interferon-beta production (GO:0032728) | 4.25333546 |
29 | cellular response to interferon-beta (GO:0035458) | 4.22184302 |
30 | regulation of cytokine secretion involved in immune response (GO:0002739) | 4.16464138 |
31 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.15981511 |
32 | negative regulation of interleukin-12 production (GO:0032695) | 4.14238713 |
33 | regulation of T-helper 1 cell differentiation (GO:0045625) | 4.10650925 |
34 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 4.09814829 |
35 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 4.04742874 |
36 | neutrophil activation involved in immune response (GO:0002283) | 3.94827945 |
37 | response to host immune response (GO:0052572) | 3.93434384 |
38 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.93434384 |
39 | positive regulation of antigen processing and presentation (GO:0002579) | 3.91753046 |
40 | cellular response to exogenous dsRNA (GO:0071360) | 3.88815957 |
41 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.82627730 |
42 | * regulation of viral genome replication (GO:0045069) | 3.74088866 |
43 | macrophage activation involved in immune response (GO:0002281) | 3.71529222 |
44 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.69450569 |
45 | regulation of vitamin metabolic process (GO:0030656) | 3.68327047 |
46 | B cell mediated immunity (GO:0019724) | 3.59915988 |
47 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 3.58634177 |
48 | cellular response to interferon-gamma (GO:0071346) | 3.58344427 |
49 | response to host (GO:0075136) | 3.50201291 |
50 | response to host defenses (GO:0052200) | 3.50201291 |
51 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.50201291 |
52 | positive regulation of defense response to virus by host (GO:0002230) | 3.49269521 |
53 | T cell migration (GO:0072678) | 3.48062703 |
54 | regulation of antigen processing and presentation (GO:0002577) | 3.47659403 |
55 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.46658061 |
56 | regulation of type 2 immune response (GO:0002828) | 3.45692476 |
57 | activation of MAPKKK activity (GO:0000185) | 3.43019856 |
58 | respiratory burst (GO:0045730) | 3.42075777 |
59 | regulation of chemokine biosynthetic process (GO:0045073) | 3.40098142 |
60 | response to muramyl dipeptide (GO:0032495) | 3.40072992 |
61 | positive regulation of interleukin-12 production (GO:0032735) | 3.37098918 |
62 | positive regulation of type 2 immune response (GO:0002830) | 3.36008881 |
63 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.35670569 |
64 | natural killer cell mediated immunity (GO:0002228) | 3.32657210 |
65 | natural killer cell mediated cytotoxicity (GO:0042267) | 3.32657210 |
66 | positive regulation of natural killer cell differentiation (GO:0032825) | 3.31521249 |
67 | T-helper 1 type immune response (GO:0042088) | 3.30504102 |
68 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 3.30436483 |
69 | response to interferon-gamma (GO:0034341) | 3.27546044 |
70 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.26834197 |
71 | germinal center formation (GO:0002467) | 3.24156152 |
72 | regulation of RIG-I signaling pathway (GO:0039535) | 3.22472079 |
73 | myeloid dendritic cell differentiation (GO:0043011) | 3.20546544 |
74 | regulation of immunoglobulin secretion (GO:0051023) | 3.20096739 |
75 | regulation of podosome assembly (GO:0071801) | 3.19514284 |
76 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.19034987 |
77 | regulation of interferon-beta production (GO:0032648) | 3.17862371 |
78 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.17151769 |
79 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 3.16888918 |
80 | dendritic cell differentiation (GO:0097028) | 3.16778401 |
81 | lymphocyte chemotaxis (GO:0048247) | 3.16454507 |
82 | granulocyte activation (GO:0036230) | 3.13429757 |
83 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.11931531 |
84 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.11183920 |
85 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.10707188 |
86 | NIK/NF-kappaB signaling (GO:0038061) | 3.10612607 |
87 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.08826463 |
88 | defense response to protozoan (GO:0042832) | 3.08741709 |
89 | regulation of mononuclear cell migration (GO:0071675) | 3.08338739 |
90 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.07894852 |
91 | regulation of T-helper cell differentiation (GO:0045622) | 3.05268293 |
92 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.05196078 |
93 | microglial cell activation (GO:0001774) | 3.05012410 |
94 | regulation of defense response to virus by host (GO:0050691) | 3.03791497 |
95 | * defense response to virus (GO:0051607) | 3.03556835 |
96 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.03533305 |
97 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 3.01834768 |
98 | positive regulation of heat generation (GO:0031652) | 3.01300658 |
99 | positive regulation of cytokine-mediated signaling pathway (GO:0001961) | 2.98678009 |
100 | eosinophil chemotaxis (GO:0048245) | 2.97546679 |
101 | interferon-gamma secretion (GO:0072643) | 2.97511621 |
102 | positive regulation of interleukin-17 production (GO:0032740) | 2.95300363 |
103 | positive regulation of humoral immune response (GO:0002922) | 2.93337631 |
104 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 2.91295967 |
105 | myeloid dendritic cell activation (GO:0001773) | 2.90829854 |
106 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.90654962 |
107 | regulation of activation of Janus kinase activity (GO:0010533) | 2.90463023 |
108 | cellular response to lipopolysaccharide (GO:0071222) | 2.90309181 |
109 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 2.89554636 |
110 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 2.89546600 |
111 | regulation of MHC class I biosynthetic process (GO:0045343) | 2.88688281 |
112 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.88235835 |
113 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.88185571 |
114 | negative regulation of cell killing (GO:0031342) | 2.88185571 |
115 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.87342384 |
116 | neutrophil activation (GO:0042119) | 2.87237791 |
117 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.86451091 |
118 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.86171276 |
119 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 2.85843410 |
120 | regulation of interleukin-12 production (GO:0032655) | 2.85328494 |
121 | * negative regulation of type I interferon production (GO:0032480) | 2.84508841 |
122 | regulation of fever generation (GO:0031620) | 2.84452964 |
123 | positive regulation of response to cytokine stimulus (GO:0060760) | 2.82836056 |
124 | myeloid cell activation involved in immune response (GO:0002275) | 2.82558299 |
125 | positive regulation of acute inflammatory response (GO:0002675) | 2.82502900 |
126 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 2.81096354 |
127 | cellular response to molecule of bacterial origin (GO:0071219) | 2.80676846 |
128 | positive regulation of cAMP-mediated signaling (GO:0043950) | 2.78421322 |
129 | * negative regulation of viral process (GO:0048525) | 2.78179108 |
130 | positive regulation of chemokine production (GO:0032722) | 2.77882584 |
131 | regulation of response to interferon-gamma (GO:0060330) | 2.77072556 |
132 | regulation of interleukin-17 production (GO:0032660) | 2.76869675 |
133 | response to protozoan (GO:0001562) | 2.76129583 |
134 | monocyte chemotaxis (GO:0002548) | 2.75730821 |
135 | response to exogenous dsRNA (GO:0043330) | 2.75722201 |
136 | low-density lipoprotein particle clearance (GO:0034383) | 2.75238536 |
137 | positive regulation of cytokine biosynthetic process (GO:0042108) | 2.74401969 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 8.30786224 |
2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 6.81399114 |
3 | * IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 6.43179217 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 5.14824383 |
5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.66585869 |
6 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.90503044 |
7 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.75065704 |
8 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.36456114 |
9 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.34861817 |
10 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.22102850 |
11 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.08716026 |
12 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.01239142 |
13 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.70944030 |
14 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.68983422 |
15 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.62214903 |
16 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.61369838 |
17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.46722993 |
18 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.46679998 |
19 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.38397444 |
20 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.16605190 |
21 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 2.13504849 |
22 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.02930820 |
23 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.95934664 |
24 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.87899285 |
25 | GATA1_22025678_ChIP-Seq_K562_Human | 1.83587851 |
26 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.77903409 |
27 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.77880880 |
28 | * MAF_26560356_Chip-Seq_TH1_Human | 1.73836879 |
29 | MYB_26560356_Chip-Seq_TH2_Human | 1.61033176 |
30 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.57954879 |
31 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.51625039 |
32 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.51247090 |
33 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.49715070 |
34 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.49263248 |
35 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46411839 |
36 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.45726046 |
37 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.45492843 |
38 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.39578933 |
39 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.38230284 |
40 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.37367037 |
41 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.34816839 |
42 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.33656801 |
43 | MYB_26560356_Chip-Seq_TH1_Human | 1.32971834 |
44 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.31117818 |
45 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.29131030 |
46 | MYC_22102868_ChIP-Seq_BL_Human | 1.27160497 |
47 | SPI1_23127762_ChIP-Seq_K562_Human | 1.24883003 |
48 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.21269692 |
49 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.21061419 |
50 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.20260998 |
51 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.19394747 |
52 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.18691205 |
53 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17978520 |
54 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.17790537 |
55 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.17376393 |
56 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.17189318 |
57 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.17185392 |
58 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.15426773 |
59 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.11049197 |
60 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.10798600 |
61 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.09817630 |
62 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.09053844 |
63 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.08830095 |
64 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.08140922 |
65 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.07778434 |
66 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.07287846 |
67 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.06765152 |
68 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04983649 |
69 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.04795606 |
70 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.04274834 |
71 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.02889055 |
72 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.01528794 |
73 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.00663426 |
74 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.00588031 |
75 | GATA3_26560356_Chip-Seq_TH2_Human | 1.00284256 |
76 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.00143501 |
77 | * SOX2_20726797_ChIP-Seq_SW620_Human | 0.99869053 |
78 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.99763924 |
79 | * MAF_26560356_Chip-Seq_TH2_Human | 0.99605279 |
80 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99160244 |
81 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.99113351 |
82 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 0.98282691 |
83 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.97727465 |
84 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.95269424 |
85 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94215289 |
86 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.93950518 |
87 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.93756476 |
88 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.93678057 |
89 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.93061071 |
90 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.93000214 |
91 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.91668721 |
92 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.90637264 |
93 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88972867 |
94 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.88814390 |
95 | * ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.87448600 |
96 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.87395399 |
97 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.83406294 |
98 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.82601707 |
99 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.81615988 |
100 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 0.78804089 |
101 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.78074100 |
102 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.77792041 |
103 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.77086451 |
104 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.76675558 |
105 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.76654397 |
106 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.76193510 |
107 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.75932677 |
108 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.75930719 |
109 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.74827864 |
110 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.74598207 |
111 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.74598207 |
112 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.74247248 |
113 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.74155128 |
114 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.73537260 |
115 | * LXR_22292898_ChIP-Seq_THP-1_Human | 0.70445124 |
116 | GATA2_19941826_ChIP-Seq_K562_Human | 0.69695814 |
117 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.67470256 |
118 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.66456197 |
119 | * KDM2B_26808549_Chip-Seq_DND41_Human | 0.66007416 |
120 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.63450951 |
121 | GATA1_19941826_ChIP-Seq_K562_Human | 0.63107406 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 4.50684688 |
2 | MP0009785_altered_susceptibility_to | 4.18552269 |
3 | MP0003436_decreased_susceptibility_to | 3.50434231 |
4 | MP0006082_CNS_inflammation | 3.44324198 |
5 | MP0003303_peritoneal_inflammation | 3.40782392 |
6 | MP0003724_increased_susceptibility_to | 3.36490955 |
7 | MP0002148_abnormal_hypersensitivity_rea | 3.32091245 |
8 | MP0004510_myositis | 3.16801548 |
9 | MP0005000_abnormal_immune_tolerance | 3.11219173 |
10 | MP0005025_abnormal_response_to | 3.11109090 |
11 | MP0005387_immune_system_phenotype | 3.08145802 |
12 | MP0001790_abnormal_immune_system | 3.08145802 |
13 | MP0000685_abnormal_immune_system | 3.01083961 |
14 | MP0005671_abnormal_response_to | 2.85467818 |
15 | MP0002419_abnormal_innate_immunity | 2.78995194 |
16 | MP0001800_abnormal_humoral_immune | 2.52341536 |
17 | MP0002452_abnormal_antigen_presenting | 2.51192695 |
18 | MP0002723_abnormal_immune_serum | 2.50525832 |
19 | MP0004947_skin_inflammation | 2.42749842 |
20 | MP0001819_abnormal_immune_cell | 2.15930471 |
21 | MP0001533_abnormal_skeleton_physiology | 2.14169245 |
22 | MP0002420_abnormal_adaptive_immunity | 2.10529838 |
23 | MP0009764_decreased_sensitivity_to | 2.07325469 |
24 | MP0002006_tumorigenesis | 2.05894726 |
25 | MP0005451_abnormal_body_composition | 2.01015325 |
26 | MP0003806_abnormal_nucleotide_metabolis | 1.97436031 |
27 | MP0005058_abnormal_lysosome_morphology | 1.95718606 |
28 | MP0002166_altered_tumor_susceptibility | 1.90269387 |
29 | MP0001853_heart_inflammation | 1.90095094 |
30 | MP0002139_abnormal_hepatobiliary_system | 1.88496015 |
31 | MP0010155_abnormal_intestine_physiology | 1.88145279 |
32 | MP0001845_abnormal_inflammatory_respons | 1.87341545 |
33 | MP0008469_abnormal_protein_level | 1.84524646 |
34 | MP0005464_abnormal_platelet_physiology | 1.82667201 |
35 | MP0009840_abnormal_foam_cell | 1.79451284 |
36 | MP0003448_altered_tumor_morphology | 1.79433924 |
37 | MP0000343_altered_response_to | 1.78604683 |
38 | MP0002332_abnormal_exercise_endurance | 1.76830873 |
39 | MP0002405_respiratory_system_inflammati | 1.72822694 |
40 | MP0008004_abnormal_stomach_pH | 1.72322262 |
41 | MP0006054_spinal_hemorrhage | 1.69160149 |
42 | MP0005310_abnormal_salivary_gland | 1.61020131 |
43 | MP0009333_abnormal_splenocyte_physiolog | 1.60532449 |
44 | MP0000716_abnormal_immune_system | 1.58724953 |
45 | MP0002398_abnormal_bone_marrow | 1.51173342 |
46 | MP0003075_altered_response_to | 1.50477181 |
47 | MP0003191_abnormal_cellular_cholesterol | 1.47502942 |
48 | MP0002138_abnormal_hepatobiliary_system | 1.44461206 |
49 | MP0009278_abnormal_bone_marrow | 1.42653070 |
50 | MP0004858_abnormal_nervous_system | 1.42550885 |
51 | MP0002998_abnormal_bone_remodeling | 1.36988349 |
52 | MP0000604_amyloidosis | 1.30576629 |
53 | MP0003300_gastrointestinal_ulcer | 1.29834204 |
54 | MP0000858_altered_metastatic_potential | 1.29458561 |
55 | MP0002429_abnormal_blood_cell | 1.26864509 |
56 | MP0003453_abnormal_keratinocyte_physiol | 1.25486141 |
57 | MP0002254_reproductive_system_inflammat | 1.24192490 |
58 | MP0005397_hematopoietic_system_phenotyp | 1.17941024 |
59 | MP0001545_abnormal_hematopoietic_system | 1.17941024 |
60 | MP0004782_abnormal_surfactant_physiolog | 1.17791454 |
61 | MP0000689_abnormal_spleen_morphology | 1.15256910 |
62 | MP0002722_abnormal_immune_system | 1.13962640 |
63 | MP0001542_abnormal_bone_strength | 1.13614843 |
64 | MP0003763_abnormal_thymus_physiology | 1.12484765 |
65 | MP0005164_abnormal_response_to | 1.12446243 |
66 | MP0010307_abnormal_tumor_latency | 1.09214169 |
67 | MP0002933_joint_inflammation | 1.08845977 |
68 | MP0005166_decreased_susceptibility_to | 1.07673266 |
69 | MP0009763_increased_sensitivity_to | 1.06106291 |
70 | MP0005390_skeleton_phenotype | 1.03324727 |
71 | MP0005023_abnormal_wound_healing | 1.02287551 |
72 | MP0003186_abnormal_redox_activity | 1.02087880 |
73 | MP0005167_abnormal_blood-brain_barrier | 1.01190567 |
74 | MP0003172_abnormal_lysosome_physiology | 1.00233612 |
75 | MP0005083_abnormal_biliary_tract | 0.93887999 |
76 | MP0002277_abnormal_respiratory_mucosa | 0.91485770 |
77 | MP0005076_abnormal_cell_differentiation | 0.91373101 |
78 | MP0010352_gastrointestinal_tract_polyps | 0.90503363 |
79 | MP0008438_abnormal_cutaneous_collagen | 0.89715859 |
80 | MP0001851_eye_inflammation | 0.89500159 |
81 | MP0003091_abnormal_cell_migration | 0.88676576 |
82 | MP0001873_stomach_inflammation | 0.85769771 |
83 | MP0008260_abnormal_autophagy | 0.84669304 |
84 | MP0000249_abnormal_blood_vessel | 0.82128316 |
85 | MP0003045_fibrosis | 0.79458012 |
86 | MP0008874_decreased_physiological_sensi | 0.78273241 |
87 | MP0003566_abnormal_cell_adhesion | 0.78192476 |
88 | MP0004883_abnormal_blood_vessel | 0.72797620 |
89 | MP0001348_abnormal_lacrimal_gland | 0.72556565 |
90 | MP0003656_abnormal_erythrocyte_physiolo | 0.71355105 |
91 | MP0002877_abnormal_melanocyte_morpholog | 0.69222050 |
92 | MP0001958_emphysema | 0.68430840 |
93 | MP0002136_abnormal_kidney_physiology | 0.66374179 |
94 | MP0003183_abnormal_peptide_metabolism | 0.65716146 |
95 | MP0003195_calcinosis | 0.65640636 |
96 | MP0003690_abnormal_glial_cell | 0.65630717 |
97 | MP0005266_abnormal_metabolism | 0.64448123 |
98 | MP0000920_abnormal_myelination | 0.63950305 |
99 | MP0003705_abnormal_hypodermis_morpholog | 0.63655251 |
100 | MP0000609_abnormal_liver_physiology | 0.62196450 |
101 | MP0005666_abnormal_adipose_tissue | 0.62173697 |
102 | MP0003795_abnormal_bone_structure | 0.61066267 |
103 | MP0004808_abnormal_hematopoietic_stem | 0.60924928 |
104 | MP0001881_abnormal_mammary_gland | 0.59190647 |
105 | MP0001501_abnormal_sleep_pattern | 0.59162036 |
106 | MP0005319_abnormal_enzyme/_coenzyme | 0.58971846 |
107 | MP0000703_abnormal_thymus_morphology | 0.58585354 |
108 | MP0003866_abnormal_defecation | 0.58512027 |
109 | MP0003828_pulmonary_edema | 0.55507881 |
110 | MP0001216_abnormal_epidermal_layer | 0.54557881 |
111 | MP0009765_abnormal_xenobiotic_induced | 0.54212060 |
112 | MP0001663_abnormal_digestive_system | 0.53371316 |
113 | MP0000490_abnormal_crypts_of | 0.52664968 |
114 | MP0000767_abnormal_smooth_muscle | 0.52453033 |
115 | MP0005165_increased_susceptibility_to | 0.52290677 |
116 | MP0005257_abnormal_intraocular_pressure | 0.51692129 |
117 | MP0003646_muscle_fatigue | 0.50956608 |
118 | MP0005535_abnormal_body_temperature | 0.50774001 |
119 | MP0002693_abnormal_pancreas_physiology | 0.50022617 |
120 | MP0005647_abnormal_sex_gland | 0.48353707 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Eczematoid dermatitis (HP:0000976) | 6.40441865 |
2 | Recurrent abscess formation (HP:0002722) | 5.71014401 |
3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.62009878 |
4 | Recurrent bacterial skin infections (HP:0005406) | 5.33087129 |
5 | Chronic otitis media (HP:0000389) | 5.21363025 |
6 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.00172608 |
7 | Autoimmune thrombocytopenia (HP:0001973) | 4.94193675 |
8 | Abnormality of macrophages (HP:0004311) | 4.54678946 |
9 | Increased IgM level (HP:0003496) | 4.53547115 |
10 | Orchitis (HP:0100796) | 4.44162710 |
11 | Myositis (HP:0100614) | 4.43174997 |
12 | Mediastinal lymphadenopathy (HP:0100721) | 4.24278513 |
13 | Stomatitis (HP:0010280) | 4.12107890 |
14 | Systemic lupus erythematosus (HP:0002725) | 4.11358557 |
15 | Retrobulbar optic neuritis (HP:0100654) | 3.94940854 |
16 | Optic neuritis (HP:0100653) | 3.94940854 |
17 | Nasal polyposis (HP:0100582) | 3.93784926 |
18 | Recurrent fungal infections (HP:0002841) | 3.89381026 |
19 | Vasculitis (HP:0002633) | 3.87669718 |
20 | Recurrent skin infections (HP:0001581) | 3.80912194 |
21 | Basal ganglia calcification (HP:0002135) | 3.78131666 |
22 | Abnormality of the nasal mucosa (HP:0000433) | 3.75629656 |
23 | Interstitial pulmonary disease (HP:0006530) | 3.70432573 |
24 | Recurrent viral infections (HP:0004429) | 3.68164878 |
25 | Disinhibition (HP:0000734) | 3.64995554 |
26 | Hypergammaglobulinemia (HP:0010702) | 3.50022282 |
27 | Gingivitis (HP:0000230) | 3.39834952 |
28 | Recurrent cutaneous fungal infections (HP:0011370) | 3.34707271 |
29 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.34707271 |
30 | Recurrent bronchitis (HP:0002837) | 3.27341122 |
31 | Nuclear cataract (HP:0100018) | 3.18906588 |
32 | Tetraparesis (HP:0002273) | 3.18607718 |
33 | Increased cerebral lipofuscin (HP:0011813) | 3.15860935 |
34 | Obstructive lung disease (HP:0006536) | 3.07970299 |
35 | Chronic obstructive pulmonary disease (HP:0006510) | 3.07970299 |
36 | Pulmonary infiltrates (HP:0002113) | 3.00577210 |
37 | Vacuolated lymphocytes (HP:0001922) | 2.97764044 |
38 | Autoimmune hemolytic anemia (HP:0001890) | 2.96150183 |
39 | Gangrene (HP:0100758) | 2.95767284 |
40 | Urticaria (HP:0001025) | 2.91750574 |
41 | Pustule (HP:0200039) | 2.88493329 |
42 | Porencephaly (HP:0002132) | 2.86598658 |
43 | Parakeratosis (HP:0001036) | 2.84279422 |
44 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.83782309 |
45 | Chronic sinusitis (HP:0011109) | 2.80927192 |
46 | Mutism (HP:0002300) | 2.69649473 |
47 | Encephalitis (HP:0002383) | 2.66313013 |
48 | Cellulitis (HP:0100658) | 2.64708389 |
49 | Gingival bleeding (HP:0000225) | 2.64523273 |
50 | Progressive neurologic deterioration (HP:0002344) | 2.63270301 |
51 | Thick nail (HP:0001805) | 2.61425085 |
52 | Leukocytosis (HP:0001974) | 2.61227955 |
53 | Axonal loss (HP:0003447) | 2.58454235 |
54 | T lymphocytopenia (HP:0005403) | 2.56991537 |
55 | Periodontitis (HP:0000704) | 2.56107356 |
56 | Hemoptysis (HP:0002105) | 2.55487863 |
57 | Peritonitis (HP:0002586) | 2.55359572 |
58 | Prostate neoplasm (HP:0100787) | 2.54849934 |
59 | Myocardial infarction (HP:0001658) | 2.53671945 |
60 | Vertebral compression fractures (HP:0002953) | 2.51433634 |
61 | Petechiae (HP:0000967) | 2.50903367 |
62 | Gastrointestinal infarctions (HP:0005244) | 2.49720385 |
63 | Gastrointestinal stroma tumor (HP:0100723) | 2.49615709 |
64 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.49251342 |
65 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.49251342 |
66 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.49251342 |
67 | IgA deficiency (HP:0002720) | 2.49222156 |
68 | Increased IgE level (HP:0003212) | 2.47342508 |
69 | Arterial thrombosis (HP:0004420) | 2.44989715 |
70 | Abnormality of the pleura (HP:0002103) | 2.42527842 |
71 | Joint swelling (HP:0001386) | 2.41627759 |
72 | Keratoconjunctivitis sicca (HP:0001097) | 2.40369785 |
73 | Loss of speech (HP:0002371) | 2.36929661 |
74 | Anorexia (HP:0002039) | 2.36488672 |
75 | Meningitis (HP:0001287) | 2.35632035 |
76 | Neurofibrillary tangles (HP:0002185) | 2.35421838 |
77 | Emphysema (HP:0002097) | 2.34635677 |
78 | Polyneuropathy (HP:0001271) | 2.31315134 |
79 | Purpura (HP:0000979) | 2.30643597 |
80 | Eosinophilia (HP:0001880) | 2.27998476 |
81 | Prolonged neonatal jaundice (HP:0006579) | 2.27021996 |
82 | Apathy (HP:0000741) | 2.26545119 |
83 | Abnormality of B cell number (HP:0010975) | 2.25816359 |
84 | Nephritis (HP:0000123) | 2.25512665 |
85 | Osteomyelitis (HP:0002754) | 2.23436619 |
86 | Keratoconjunctivitis (HP:0001096) | 2.23183902 |
87 | Abnormality of T cell number (HP:0011839) | 2.21592063 |
88 | Hematochezia (HP:0002573) | 2.20966772 |
89 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.20734136 |
90 | Skin ulcer (HP:0200042) | 2.18304217 |
91 | Glomerulonephritis (HP:0000099) | 2.17783215 |
92 | Recurrent lower respiratory tract infections (HP:0002783) | 2.15777516 |
93 | Recurrent pneumonia (HP:0006532) | 2.15042572 |
94 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.14879251 |
95 | Osteolytic defects of the hand bones (HP:0009699) | 2.14879251 |
96 | Diminished motivation (HP:0000745) | 2.14048321 |
97 | Dysostosis multiplex (HP:0000943) | 2.13250297 |
98 | Abnormality of glycolipid metabolism (HP:0010969) | 2.12093543 |
99 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.12093543 |
100 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.12093543 |
101 | Premature loss of primary teeth (HP:0006323) | 2.12066670 |
102 | Abnormality of the pericardium (HP:0001697) | 2.11796895 |
103 | Abnormality of T cell physiology (HP:0011840) | 2.08219988 |
104 | B lymphocytopenia (HP:0010976) | 2.07876057 |
105 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.06801720 |
106 | Colitis (HP:0002583) | 2.06020102 |
107 | Increased serum ferritin (HP:0003281) | 2.05786589 |
108 | Abnormality of T cells (HP:0002843) | 2.05353481 |
109 | Joint hemorrhage (HP:0005261) | 2.05164910 |
110 | Upper motor neuron abnormality (HP:0002127) | 2.04630871 |
111 | Hepatosplenomegaly (HP:0001433) | 2.04238551 |
112 | Bone pain (HP:0002653) | 2.04038598 |
113 | Arthralgia (HP:0002829) | 2.03087554 |
114 | Abnormality of the basal ganglia (HP:0002134) | 2.02644081 |
115 | Glomerulopathy (HP:0100820) | 2.02446971 |
116 | Abnormality of iron homeostasis (HP:0011031) | 2.00997350 |
117 | Spontaneous hematomas (HP:0007420) | 2.00837822 |
118 | Memory impairment (HP:0002354) | 2.00119421 |
119 | Nausea (HP:0002018) | 1.99413116 |
120 | Lymphopenia (HP:0001888) | 1.98630851 |
121 | Poor head control (HP:0002421) | 1.98372132 |
122 | Cheilitis (HP:0100825) | 1.97235032 |
123 | Acne (HP:0001061) | 1.96733308 |
124 | Pulmonary embolism (HP:0002204) | 1.96242516 |
125 | Malnutrition (HP:0004395) | 1.95529881 |
126 | Complement deficiency (HP:0004431) | 1.95113461 |
127 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.95082908 |
128 | Abnormality of eosinophils (HP:0001879) | 1.94347060 |
129 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.93589463 |
130 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.93068401 |
131 | Mucopolysacchariduria (HP:0008155) | 1.93068401 |
132 | Amyloidosis (HP:0011034) | 1.92508204 |
133 | Esophageal varix (HP:0002040) | 1.91825675 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TBK1 | 4.86246187 |
2 | IKBKE | 4.27392198 |
3 | TYK2 | 4.23030561 |
4 | MAP3K14 | 4.07775491 |
5 | BLK | 3.24858734 |
6 | GRK7 | 3.04472187 |
7 | JAK3 | 3.02102956 |
8 | PBK | 2.98421831 |
9 | TAOK2 | 2.92244646 |
10 | KIT | 2.87105802 |
11 | FGFR4 | 2.86067631 |
12 | ERN1 | 2.83607079 |
13 | JAK1 | 2.64625960 |
14 | IRAK3 | 2.45285101 |
15 | IRAK4 | 2.44023082 |
16 | IKBKB | 2.42537207 |
17 | MAP4K1 | 2.23490745 |
18 | TXK | 2.23028727 |
19 | RIPK4 | 2.22178452 |
20 | PIM2 | 2.08106915 |
21 | PRPF4B | 2.00604276 |
22 | TAOK1 | 1.79057859 |
23 | EPHB1 | 1.78954370 |
24 | MAP3K13 | 1.69012532 |
25 | CSK | 1.64783054 |
26 | EPHA3 | 1.60107023 |
27 | FGFR3 | 1.56113316 |
28 | MAP2K3 | 1.53314776 |
29 | CHUK | 1.49524421 |
30 | ZAP70 | 1.47630356 |
31 | NME2 | 1.43266966 |
32 | MST4 | 1.41016371 |
33 | BMX | 1.29771229 |
34 | SYK | 1.22172228 |
35 | RPS6KA4 | 1.18441550 |
36 | HCK | 1.16384098 |
37 | FGR | 1.16010600 |
38 | JAK2 | 1.10962300 |
39 | LCK | 1.05130437 |
40 | ADRBK2 | 1.03034685 |
41 | ABL2 | 1.02756928 |
42 | MATK | 0.93977157 |
43 | CDC42BPA | 0.92539491 |
44 | LYN | 0.91176777 |
45 | PIM1 | 0.90504789 |
46 | BTK | 0.89345828 |
47 | NEK9 | 0.87580091 |
48 | CSF1R | 0.86553925 |
49 | EIF2AK2 | 0.81796340 |
50 | FES | 0.80551484 |
51 | IRAK1 | 0.80050921 |
52 | HIPK2 | 0.79445333 |
53 | MST1R | 0.75555154 |
54 | TAOK3 | 0.74030818 |
55 | TGFBR2 | 0.73189859 |
56 | STK10 | 0.73184142 |
57 | MAP3K5 | 0.72871979 |
58 | STK4 | 0.72855464 |
59 | MAP3K10 | 0.72480678 |
60 | MARK3 | 0.71878598 |
61 | TESK1 | 0.68894942 |
62 | KDR | 0.67385345 |
63 | TEC | 0.66205166 |
64 | MAP2K6 | 0.63302279 |
65 | PTK6 | 0.62356790 |
66 | ARAF | 0.61201697 |
67 | EGFR | 0.60381045 |
68 | PRKCD | 0.59610666 |
69 | LRRK2 | 0.57701260 |
70 | ABL1 | 0.57658291 |
71 | SIK3 | 0.55555218 |
72 | TNK2 | 0.55411862 |
73 | BMPR2 | 0.51516261 |
74 | DAPK3 | 0.51159803 |
75 | NLK | 0.50390075 |
76 | RIPK1 | 0.50030113 |
77 | RPS6KA5 | 0.48781126 |
78 | TRIB3 | 0.48420125 |
79 | MAP3K1 | 0.47743558 |
80 | DYRK3 | 0.46741346 |
81 | CLK1 | 0.46109837 |
82 | LATS2 | 0.44712194 |
83 | GRK6 | 0.43342303 |
84 | MAPK11 | 0.41970995 |
85 | SIK1 | 0.41853879 |
86 | PAK4 | 0.41801480 |
87 | SMG1 | 0.41345396 |
88 | TTN | 0.41333052 |
89 | PRKG2 | 0.41271068 |
90 | MOS | 0.41111813 |
91 | PRKCQ | 0.37377195 |
92 | MAPKAPK2 | 0.36801708 |
93 | STK3 | 0.35854180 |
94 | MAP3K11 | 0.34844064 |
95 | ITK | 0.34338618 |
96 | EPHA2 | 0.33862981 |
97 | PKN1 | 0.32598605 |
98 | TRPM7 | 0.32446486 |
99 | ERBB4 | 0.31531847 |
100 | TESK2 | 0.31254720 |
101 | BRAF | 0.30046877 |
102 | ALK | 0.29445738 |
103 | PDK1 | 0.29230107 |
104 | TYRO3 | 0.28155786 |
105 | MAPK7 | 0.27636153 |
106 | DDR2 | 0.25837360 |
107 | INSR | 0.25492192 |
108 | FYN | 0.24627905 |
109 | SRC | 0.21815848 |
110 | ICK | 0.20941967 |
111 | RPS6KL1 | 0.19647029 |
112 | RPS6KC1 | 0.19647029 |
113 | SIK2 | 0.19644705 |
114 | RPS6KA1 | 0.18288033 |
115 | PAK1 | 0.18178249 |
116 | DYRK1B | 0.18011668 |
117 | MAPK4 | 0.17902877 |
118 | PRKCH | 0.16789739 |
119 | IGF1R | 0.16159083 |
120 | MAP3K3 | 0.15631572 |
121 | IRAK2 | 0.14630968 |
122 | PDPK1 | 0.11502865 |
123 | MAPK3 | 0.10888126 |
124 | TLK1 | 0.10811803 |
125 | CDK6 | 0.10625484 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.34687484 |
2 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 3.18584063 |
3 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 3.14748636 |
4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.08367311 |
5 | Allograft rejection_Homo sapiens_hsa05330 | 2.84651940 |
6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.78518031 |
7 | Measles_Homo sapiens_hsa05162 | 2.65349600 |
8 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.64518745 |
9 | * RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.61832273 |
10 | Malaria_Homo sapiens_hsa05144 | 2.42201161 |
11 | Legionellosis_Homo sapiens_hsa05134 | 2.31279008 |
12 | Influenza A_Homo sapiens_hsa05164 | 2.27635260 |
13 | Pertussis_Homo sapiens_hsa05133 | 2.25839664 |
14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.21718319 |
15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.17639451 |
16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.12130457 |
17 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.09894274 |
18 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.06775793 |
19 | Herpes simplex infection_Homo sapiens_hsa05168 | 2.03359762 |
20 | Tuberculosis_Homo sapiens_hsa05152 | 1.94812531 |
21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.90449133 |
22 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.81256129 |
23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.76068709 |
24 | Asthma_Homo sapiens_hsa05310 | 1.75652910 |
25 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.73948657 |
26 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.72063073 |
27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.66424993 |
28 | Salmonella infection_Homo sapiens_hsa05132 | 1.60838810 |
29 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.53249950 |
30 | Hepatitis C_Homo sapiens_hsa05160 | 1.52608642 |
31 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.49014990 |
32 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.45194676 |
33 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.40424925 |
34 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.39313977 |
35 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.34931671 |
36 | Apoptosis_Homo sapiens_hsa04210 | 1.34508991 |
37 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.30928345 |
38 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.29318819 |
39 | Hepatitis B_Homo sapiens_hsa05161 | 1.28743583 |
40 | Lysosome_Homo sapiens_hsa04142 | 1.23879294 |
41 | Shigellosis_Homo sapiens_hsa05131 | 1.21992309 |
42 | Viral myocarditis_Homo sapiens_hsa05416 | 1.18135635 |
43 | Phagosome_Homo sapiens_hsa04145 | 1.16095891 |
44 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.00304789 |
45 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.00095942 |
46 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.96245970 |
47 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.94072229 |
48 | Amoebiasis_Homo sapiens_hsa05146 | 0.90209709 |
49 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.88689245 |
50 | Other glycan degradation_Homo sapiens_hsa00511 | 0.82132409 |
51 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.82062683 |
52 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.80575670 |
53 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.79167609 |
54 | Bladder cancer_Homo sapiens_hsa05219 | 0.77140532 |
55 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.72991000 |
56 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.71941978 |
57 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.71307451 |
58 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.69350314 |
59 | Prion diseases_Homo sapiens_hsa05020 | 0.68527425 |
60 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.66380739 |
61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.66343550 |
62 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.65445103 |
63 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.61503621 |
64 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.61193658 |
65 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.60899838 |
66 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.59637454 |
67 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.57554703 |
68 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.53880368 |
69 | Mineral absorption_Homo sapiens_hsa04978 | 0.52802543 |
70 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.52405082 |
71 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.50751450 |
72 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.50323326 |
73 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.49412900 |
74 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.47456090 |
75 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.43473703 |
76 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.41403760 |
77 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.40792440 |
78 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39682813 |
79 | Galactose metabolism_Homo sapiens_hsa00052 | 0.37021844 |
80 | Proteasome_Homo sapiens_hsa03050 | 0.37007633 |
81 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.35951494 |
82 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.35539205 |
83 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.32301289 |
84 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.31609758 |
85 | Platelet activation_Homo sapiens_hsa04611 | 0.31604798 |
86 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.30963599 |
87 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.30700158 |
88 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.28532912 |
89 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.27830626 |
90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.27710112 |
91 | HTLV-I infection_Homo sapiens_hsa05166 | 0.26922294 |
92 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.26259582 |
93 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.26018012 |
94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.25118314 |
95 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.25048811 |
96 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.24840243 |
97 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.22182189 |
98 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.20160908 |
99 | ABC transporters_Homo sapiens_hsa02010 | 0.20073825 |
100 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.19651704 |
101 | Insulin resistance_Homo sapiens_hsa04931 | 0.18992819 |
102 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.18588692 |
103 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.16905978 |
104 | Sulfur relay system_Homo sapiens_hsa04122 | 0.14862371 |
105 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.14601919 |
106 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.12435930 |
107 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.12376191 |
108 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.11196673 |
109 | Endocytosis_Homo sapiens_hsa04144 | 0.10776466 |
110 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.08748943 |
111 | Histidine metabolism_Homo sapiens_hsa00340 | 0.07906345 |
112 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.06990702 |
113 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.06579961 |
114 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.05371159 |