Rank | Gene Set | Z-score |
---|---|---|
1 | hemidesmosome assembly (GO:0031581) | 7.83907650 |
2 | hepatocyte apoptotic process (GO:0097284) | 6.13225066 |
3 | * mesodermal cell differentiation (GO:0048333) | 5.84142961 |
4 | interferon-gamma secretion (GO:0072643) | 5.15969550 |
5 | renal filtration (GO:0097205) | 5.10671750 |
6 | Golgi transport vesicle coating (GO:0048200) | 4.30635323 |
7 | COPI coating of Golgi vesicle (GO:0048205) | 4.30635323 |
8 | cell-substrate junction assembly (GO:0007044) | 4.30296595 |
9 | * cell adhesion mediated by integrin (GO:0033627) | 4.21592597 |
10 | lung lobe morphogenesis (GO:0060463) | 4.21129351 |
11 | glial cell proliferation (GO:0014009) | 4.07394399 |
12 | positive regulation of establishment of protein localization to plasma membrane (GO:0090004) | 4.00267070 |
13 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.94369554 |
14 | respiratory tube development (GO:0030323) | 3.91507218 |
15 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.80321512 |
16 | cellular response to vitamin D (GO:0071305) | 3.78456060 |
17 | lung epithelium development (GO:0060428) | 3.78021317 |
18 | positive regulation of protein localization to plasma membrane (GO:1903078) | 3.77505598 |
19 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 3.71104320 |
20 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.63533861 |
21 | establishment of endothelial barrier (GO:0061028) | 3.62301987 |
22 | * skin morphogenesis (GO:0043589) | 3.61566103 |
23 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.57057741 |
24 | wound healing, spreading of epidermal cells (GO:0035313) | 3.55584847 |
25 | muscle cell migration (GO:0014812) | 3.55468261 |
26 | protein retention in ER lumen (GO:0006621) | 3.49590958 |
27 | regulation of metalloenzyme activity (GO:0048552) | 3.48727322 |
28 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.48017776 |
29 | positive regulation of osteoblast proliferation (GO:0033690) | 3.45559719 |
30 | hippo signaling (GO:0035329) | 3.43304812 |
31 | membrane raft organization (GO:0031579) | 3.41346724 |
32 | diterpenoid biosynthetic process (GO:0016102) | 3.39377782 |
33 | lens fiber cell development (GO:0070307) | 3.37296079 |
34 | growth hormone receptor signaling pathway (GO:0060396) | 3.36446878 |
35 | COPII vesicle coating (GO:0048208) | 3.31381877 |
36 | organ formation (GO:0048645) | 3.29343718 |
37 | positive regulation of Rho protein signal transduction (GO:0035025) | 3.28128023 |
38 | surfactant homeostasis (GO:0043129) | 3.23389525 |
39 | regulation of nephron tubule epithelial cell differentiation (GO:0072182) | 3.21643484 |
40 | epithelial cell-cell adhesion (GO:0090136) | 3.21144157 |
41 | cellular response to vitamin (GO:0071295) | 3.20338099 |
42 | embryonic foregut morphogenesis (GO:0048617) | 3.19221173 |
43 | desmosome organization (GO:0002934) | 3.17377108 |
44 | regulation of water loss via skin (GO:0033561) | 3.15731382 |
45 | endodermal cell differentiation (GO:0035987) | 3.14178092 |
46 | mammary gland epithelial cell proliferation (GO:0033598) | 3.12695664 |
47 | lung vasculature development (GO:0060426) | 3.12524725 |
48 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.10320531 |
49 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.09399977 |
50 | regulation of epithelial cell differentiation involved in kidney development (GO:2000696) | 3.08078685 |
51 | tight junction assembly (GO:0070830) | 3.06306553 |
52 | lymphangiogenesis (GO:0001946) | 3.00906554 |
53 | negative regulation of fibrinolysis (GO:0051918) | 3.00063751 |
54 | regulation of transforming growth factor beta2 production (GO:0032909) | 2.97889772 |
55 | thrombin receptor signaling pathway (GO:0070493) | 2.96208244 |
56 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 2.96008581 |
57 | establishment of skin barrier (GO:0061436) | 2.95853691 |
58 | regulation of keratinocyte proliferation (GO:0010837) | 2.94929382 |
59 | lung-associated mesenchyme development (GO:0060484) | 2.94764592 |
60 | gap junction assembly (GO:0016264) | 2.93837905 |
61 | regulation of glomerular filtration (GO:0003093) | 2.92124481 |
62 | kidney morphogenesis (GO:0060993) | 2.91333951 |
63 | regulation of transforming growth factor beta production (GO:0071634) | 2.90938636 |
64 | wound healing, spreading of cells (GO:0044319) | 2.90706933 |
65 | fibrinolysis (GO:0042730) | 2.90450436 |
66 | cellular response to growth hormone stimulus (GO:0071378) | 2.90170819 |
67 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.89298239 |
68 | membrane budding (GO:0006900) | 2.89011819 |
69 | intestinal epithelial cell development (GO:0060576) | 2.88844851 |
70 | activation of Rac GTPase activity (GO:0032863) | 2.88806374 |
71 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.85509163 |
72 | adherens junction assembly (GO:0034333) | 2.84927575 |
73 | decidualization (GO:0046697) | 2.84821226 |
74 | polarized epithelial cell differentiation (GO:0030859) | 2.83451134 |
75 | positive regulation of extracellular matrix organization (GO:1903055) | 2.83210350 |
76 | positive regulation of actin filament depolymerization (GO:0030836) | 2.80081268 |
77 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.79717158 |
78 | protein hydroxylation (GO:0018126) | 2.75429692 |
79 | negative regulation of fatty acid transport (GO:2000192) | 2.75100879 |
80 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.74934578 |
81 | membrane protein ectodomain proteolysis (GO:0006509) | 2.74188227 |
82 | protein localization to endosome (GO:0036010) | 2.74151641 |
83 | cell differentiation involved in embryonic placenta development (GO:0060706) | 2.73476423 |
84 | positive regulation of tolerance induction (GO:0002645) | 2.73214870 |
85 | cell junction assembly (GO:0034329) | 2.72300510 |
86 | regulation of chemokine secretion (GO:0090196) | 2.70272239 |
87 | regulation of plasminogen activation (GO:0010755) | 2.69780245 |
88 | renal system development (GO:0072001) | 2.69744256 |
89 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 2.68758004 |
90 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.68113445 |
91 | regulation of podosome assembly (GO:0071801) | 2.67093719 |
92 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.65988627 |
93 | stress fiber assembly (GO:0043149) | 2.63697427 |
94 | positive regulation of astrocyte differentiation (GO:0048711) | 2.63457010 |
95 | * hypotonic response (GO:0006971) | 2.63448564 |
96 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.62464881 |
97 | tyrosine phosphorylation of STAT protein (GO:0007260) | 2.62426833 |
98 | semaphorin-plexin signaling pathway (GO:0071526) | 2.62016830 |
99 | * substrate-dependent cell migration (GO:0006929) | 2.60857153 |
100 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.60638605 |
101 | endocardial cushion development (GO:0003197) | 2.60196979 |
102 | establishment of tissue polarity (GO:0007164) | 2.59712408 |
103 | establishment of planar polarity (GO:0001736) | 2.59712408 |
104 | keratinocyte differentiation (GO:0030216) | 2.59310903 |
105 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.59094966 |
106 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.58695989 |
107 | regulation of epidermal growth factor-activated receptor activity (GO:0007176) | 2.58410600 |
108 | cell junction organization (GO:0034330) | 2.57766035 |
109 | negative regulation of stem cell proliferation (GO:2000647) | 2.57319657 |
110 | keratinocyte proliferation (GO:0043616) | 2.57056282 |
111 | cellular copper ion homeostasis (GO:0006878) | 2.56930967 |
112 | endothelial cell morphogenesis (GO:0001886) | 2.56296779 |
113 | regulation of T cell tolerance induction (GO:0002664) | 2.55790505 |
114 | regulation of osteoblast proliferation (GO:0033688) | 2.55097564 |
115 | collagen metabolic process (GO:0032963) | 2.54960892 |
116 | chondrocyte proliferation (GO:0035988) | 2.54815360 |
117 | apoptotic cell clearance (GO:0043277) | 2.53998619 |
118 | protein localization to cell surface (GO:0034394) | 2.53548710 |
119 | regulation of interleukin-8 secretion (GO:2000482) | 2.52636518 |
120 | vesicle coating (GO:0006901) | 2.51346757 |
121 | * wound healing (GO:0042060) | 2.51282704 |
122 | focal adhesion assembly (GO:0048041) | 2.50593468 |
123 | cell-substrate adherens junction assembly (GO:0007045) | 2.50593468 |
124 | negative regulation of cartilage development (GO:0061037) | 2.50384908 |
125 | negative regulation of anoikis (GO:2000811) | 2.49615826 |
126 | cell-cell junction assembly (GO:0007043) | 2.49156516 |
127 | chemical homeostasis within a tissue (GO:0048875) | 2.49028747 |
128 | renal system process involved in regulation of blood volume (GO:0001977) | 2.48458423 |
129 | regulation of establishment of protein localization to plasma membrane (GO:0090003) | 2.46892419 |
130 | hyaluronan catabolic process (GO:0030214) | 2.46575071 |
131 | basement membrane organization (GO:0071711) | 2.45742751 |
132 | adherens junction organization (GO:0034332) | 2.45043718 |
133 | peptidyl-proline hydroxylation (GO:0019511) | 2.44328986 |
134 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.43202078 |
135 | blood vessel endothelial cell migration (GO:0043534) | 2.42414394 |
136 | collagen catabolic process (GO:0030574) | 2.42240943 |
137 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.42104991 |
138 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.42038206 |
139 | actin filament depolymerization (GO:0030042) | 2.41948080 |
140 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.41224395 |
141 | regulation of tight junction assembly (GO:2000810) | 2.41173116 |
142 | O-glycan processing (GO:0016266) | 2.41054169 |
143 | positive regulation of pseudopodium assembly (GO:0031274) | 2.40740088 |
144 | regulation of transforming growth factor beta1 production (GO:0032908) | 2.40535707 |
145 | extracellular matrix disassembly (GO:0022617) | 2.40288907 |
146 | negative regulation of cell fate specification (GO:0009996) | 2.39818981 |
147 | mRNA transcription (GO:0009299) | 2.39816008 |
148 | positive regulation of transforming growth factor beta production (GO:0071636) | 2.39323499 |
149 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.38680223 |
150 | * positive regulation of epithelial cell migration (GO:0010634) | 2.38673105 |
151 | glomerular visceral epithelial cell development (GO:0072015) | 2.38657272 |
152 | iron ion import (GO:0097286) | 2.38247876 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 8.77663842 |
2 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 4.45045171 |
3 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.24590036 |
4 | * SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 3.83637398 |
5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.57098630 |
6 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.45444625 |
7 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.16263204 |
8 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.82411015 |
9 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 2.62955941 |
10 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 2.62955941 |
11 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.60499440 |
12 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.48022195 |
13 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.46724396 |
14 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.46184862 |
15 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.39481056 |
16 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.39275361 |
17 | * FOXO3_23340844_ChIP-Seq_DLD1_Human | 2.26217638 |
18 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.18826960 |
19 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.13240508 |
20 | * PPAR_26484153_Chip-Seq_NCI-H1993_Human | 2.12613583 |
21 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 2.12390928 |
22 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.08569330 |
23 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 2.06696188 |
24 | SOX2_20726797_ChIP-Seq_SW620_Human | 2.05857731 |
25 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.99331714 |
26 | CJUN_26792858_Chip-Seq_BT549_Human | 1.98667060 |
27 | * GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.93491672 |
28 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.85889257 |
29 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.85702659 |
30 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.85599783 |
31 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.85036619 |
32 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.69690614 |
33 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.66618289 |
34 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.63191319 |
35 | * GATA6_25053715_ChIP-Seq_YYC3_Human | 1.61031036 |
36 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.59213129 |
37 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.58672891 |
38 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.57385986 |
39 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.56680903 |
40 | * GATA4_25053715_ChIP-Seq_YYC3_Human | 1.56024819 |
41 | * FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.54976628 |
42 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.53096201 |
43 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.52803958 |
44 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.51979583 |
45 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.51571878 |
46 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.48387259 |
47 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 1.47097449 |
48 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.45375352 |
49 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.43788882 |
50 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.41917553 |
51 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.41203636 |
52 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.39718928 |
53 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.36662712 |
54 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.33181921 |
55 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.29359902 |
56 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.29329530 |
57 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.27876576 |
58 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.27518405 |
59 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.26055905 |
60 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.25995176 |
61 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.25458358 |
62 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.24593667 |
63 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.24259310 |
64 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.23933496 |
65 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.23337092 |
66 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.22738429 |
67 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.22158685 |
68 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.21454259 |
69 | * GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.18987992 |
70 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.18600272 |
71 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.17591242 |
72 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.16524492 |
73 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.16524492 |
74 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.15802344 |
75 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.15339641 |
76 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.11877863 |
77 | * ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.11502961 |
78 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.11460827 |
79 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.09765137 |
80 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.09234830 |
81 | * FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.08121986 |
82 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.07613367 |
83 | TP53_16413492_ChIP-PET_HCT116_Human | 1.06896814 |
84 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.06457816 |
85 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.05336958 |
86 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.04435665 |
87 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.03675398 |
88 | * CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.03240108 |
89 | * TP63_23658742_ChIP-Seq_EP156T_Human | 1.02651769 |
90 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.01954048 |
91 | * NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.00462669 |
92 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.99174602 |
93 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.98638850 |
94 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.96766113 |
95 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.94502384 |
96 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.93969233 |
97 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.93514797 |
98 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.93194483 |
99 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.92673233 |
100 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.92472605 |
101 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.92161481 |
102 | GATA2_19941826_ChIP-Seq_K562_Human | 0.91681062 |
103 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.89223841 |
104 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.88958853 |
105 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.87676567 |
106 | * NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.87335077 |
107 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.86083733 |
108 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.85994185 |
109 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.85433332 |
110 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.84976386 |
111 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.84728793 |
112 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.84725696 |
113 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.84099121 |
114 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.82577459 |
115 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.81775113 |
116 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.80941352 |
117 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.80941352 |
118 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 0.78357174 |
119 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.76421634 |
120 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.74779122 |
121 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.74674509 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000537_abnormal_urethra_morphology | 5.00699667 |
2 | MP0010234_abnormal_vibrissa_follicle | 4.44741644 |
3 | MP0003705_abnormal_hypodermis_morpholog | 3.64611070 |
4 | MP0000579_abnormal_nail_morphology | 3.48704002 |
5 | MP0010352_gastrointestinal_tract_polyps | 3.24791146 |
6 | MP0003300_gastrointestinal_ulcer | 3.20487800 |
7 | MP0004272_abnormal_basement_membrane | 3.16082251 |
8 | MP0006054_spinal_hemorrhage | 2.88999154 |
9 | MP0003941_abnormal_skin_development | 2.84836734 |
10 | MP0003566_abnormal_cell_adhesion | 2.55373901 |
11 | MP0009780_abnormal_chondrocyte_physiolo | 2.49853284 |
12 | MP0003950_abnormal_plasma_membrane | 2.49437232 |
13 | MP0003045_fibrosis | 2.39596488 |
14 | MP0004264_abnormal_extraembryonic_tissu | 2.31898008 |
15 | MP0010368_abnormal_lymphatic_system | 2.27968020 |
16 | MP0005023_abnormal_wound_healing | 2.22331408 |
17 | MP0005257_abnormal_intraocular_pressure | 2.20678430 |
18 | MP0005409_darkened_coat_color | 2.15016794 |
19 | MP0010678_abnormal_skin_adnexa | 2.06750179 |
20 | MP0009053_abnormal_anal_canal | 1.99766627 |
21 | MP0009384_cardiac_valve_regurgitation | 1.94828688 |
22 | MP0005275_abnormal_skin_tensile | 1.93534838 |
23 | MP0001879_abnormal_lymphatic_vessel | 1.85735110 |
24 | MP0003453_abnormal_keratinocyte_physiol | 1.76902413 |
25 | MP0003091_abnormal_cell_migration | 1.71039217 |
26 | MP0001849_ear_inflammation | 1.68671246 |
27 | MP0010155_abnormal_intestine_physiology | 1.57470702 |
28 | MP0000462_abnormal_digestive_system | 1.57290231 |
29 | MP0000858_altered_metastatic_potential | 1.54776465 |
30 | MP0000678_abnormal_parathyroid_gland | 1.51157776 |
31 | MP0005248_abnormal_Harderian_gland | 1.46459525 |
32 | MP0003828_pulmonary_edema | 1.42940399 |
33 | MP0002282_abnormal_trachea_morphology | 1.40575711 |
34 | MP0003866_abnormal_defecation | 1.39660410 |
35 | MP0002060_abnormal_skin_morphology | 1.39140181 |
36 | MP0001881_abnormal_mammary_gland | 1.38573449 |
37 | MP0005623_abnormal_meninges_morphology | 1.38309644 |
38 | MP0004947_skin_inflammation | 1.38218659 |
39 | MP0003115_abnormal_respiratory_system | 1.38117628 |
40 | MP0002896_abnormal_bone_mineralization | 1.37286302 |
41 | MP0001216_abnormal_epidermal_layer | 1.36956791 |
42 | MP0000383_abnormal_hair_follicle | 1.35570910 |
43 | MP0002877_abnormal_melanocyte_morpholog | 1.33233766 |
44 | MP0003191_abnormal_cellular_cholesterol | 1.31493863 |
45 | MP0002796_impaired_skin_barrier | 1.29987332 |
46 | MP0003315_abnormal_perineum_morphology | 1.29421833 |
47 | MP0008438_abnormal_cutaneous_collagen | 1.26844566 |
48 | MP0002254_reproductive_system_inflammat | 1.23449953 |
49 | MP0005360_urolithiasis | 1.23019373 |
50 | * MP0000627_abnormal_mammary_gland | 1.22207502 |
51 | MP0001299_abnormal_eye_distance/ | 1.21592862 |
52 | MP0003448_altered_tumor_morphology | 1.20250783 |
53 | MP0005501_abnormal_skin_physiology | 1.19196205 |
54 | MP0001873_stomach_inflammation | 1.14526369 |
55 | MP0002098_abnormal_vibrissa_morphology | 1.13742084 |
56 | MP0000477_abnormal_intestine_morphology | 1.11907626 |
57 | MP0000013_abnormal_adipose_tissue | 1.11613932 |
58 | MP0005076_abnormal_cell_differentiation | 1.10885208 |
59 | MP0005167_abnormal_blood-brain_barrier | 1.10063704 |
60 | MP0002089_abnormal_postnatal_growth/wei | 1.09282052 |
61 | MP0001853_heart_inflammation | 1.09236931 |
62 | MP0003303_peritoneal_inflammation | 1.08972211 |
63 | MP0003279_aneurysm | 1.07377572 |
64 | MP0004782_abnormal_surfactant_physiolog | 1.04207935 |
65 | MP0005197_abnormal_uvea_morphology | 1.02716931 |
66 | MP0001958_emphysema | 1.00362644 |
67 | MP0002234_abnormal_pharynx_morphology | 0.98741969 |
68 | MP0001663_abnormal_digestive_system | 0.98379049 |
69 | MP0009697_abnormal_copulation | 0.97845316 |
70 | MP0002168_other_aberrant_phenotype | 0.97311682 |
71 | MP0005381_digestive/alimentary_phenotyp | 0.96666746 |
72 | MP0000733_abnormal_muscle_development | 0.96213726 |
73 | MP0000377_abnormal_hair_follicle | 0.95111394 |
74 | MP0010030_abnormal_orbit_morphology | 0.94523838 |
75 | MP0002933_joint_inflammation | 0.93746033 |
76 | MP0000465_gastrointestinal_hemorrhage | 0.93537756 |
77 | MP0004883_abnormal_blood_vessel | 0.93018760 |
78 | MP0000762_abnormal_tongue_morphology | 0.92994357 |
79 | MP0000767_abnormal_smooth_muscle | 0.92182510 |
80 | MP0005165_increased_susceptibility_to | 0.91908693 |
81 | MP0002925_abnormal_cardiovascular_devel | 0.91852461 |
82 | MP0009840_abnormal_foam_cell | 0.87431238 |
83 | MP0003755_abnormal_palate_morphology | 0.86261169 |
84 | MP0005164_abnormal_response_to | 0.85096030 |
85 | MP0000490_abnormal_crypts_of | 0.84649017 |
86 | MP0003868_abnormal_feces_composition | 0.84385346 |
87 | MP0002086_abnormal_extraembryonic_tissu | 0.84322295 |
88 | MP0002177_abnormal_outer_ear | 0.83405175 |
89 | MP0003385_abnormal_body_wall | 0.83096086 |
90 | MP0001533_abnormal_skeleton_physiology | 0.82746449 |
91 | MP0010771_integument_phenotype | 0.82072761 |
92 | MP0000467_abnormal_esophagus_morphology | 0.81952380 |
93 | MP0002295_abnormal_pulmonary_circulatio | 0.81420411 |
94 | MP0009785_altered_susceptibility_to | 0.81189270 |
95 | MP0000249_abnormal_blood_vessel | 0.80993234 |
96 | MP0000003_abnormal_adipose_tissue | 0.80782151 |
97 | MP0003119_abnormal_digestive_system | 0.80261189 |
98 | MP0001191_abnormal_skin_condition | 0.79523436 |
99 | MP0001915_intracranial_hemorrhage | 0.77936122 |
100 | MP0000163_abnormal_cartilage_morphology | 0.76924266 |
101 | MP0005451_abnormal_body_composition | 0.76621106 |
102 | MP0000432_abnormal_head_morphology | 0.75846551 |
103 | MP0001614_abnormal_blood_vessel | 0.75838442 |
104 | MP0004233_abnormal_muscle_weight | 0.75089904 |
105 | MP0002006_tumorigenesis | 0.75009262 |
106 | MP0005408_hypopigmentation | 0.74951921 |
107 | MP0001243_abnormal_dermal_layer | 0.74837453 |
108 | MP0008004_abnormal_stomach_pH | 0.73390424 |
109 | MP0004808_abnormal_hematopoietic_stem | 0.72907400 |
110 | MP0010307_abnormal_tumor_latency | 0.72633178 |
111 | MP0003935_abnormal_craniofacial_develop | 0.72090155 |
112 | MP0000751_myopathy | 0.72077062 |
113 | MP0005508_abnormal_skeleton_morphology | 0.71224605 |
114 | MP0006138_congestive_heart_failure | 0.70906654 |
115 | MP0000534_abnormal_ureter_morphology | 0.70742227 |
116 | MP0005621_abnormal_cell_physiology | 0.70074081 |
117 | MP0009931_abnormal_skin_appearance | 0.69941269 |
118 | MP0002697_abnormal_eye_size | 0.69404655 |
119 | MP0005193_abnormal_anterior_eye | 0.68963891 |
120 | MP0002113_abnormal_skeleton_development | 0.68549859 |
121 | MP0001784_abnormal_fluid_regulation | 0.67953823 |
122 | MP0000647_abnormal_sebaceous_gland | 0.67001798 |
123 | MP0000428_abnormal_craniofacial_morphol | 0.66849172 |
124 | MP0009250_abnormal_appendicular_skeleto | 0.66346867 |
125 | MP0003937_abnormal_limbs/digits/tail_de | 0.66187623 |
126 | MP0009278_abnormal_bone_marrow | 0.65746909 |
127 | MP0005166_decreased_susceptibility_to | 0.65710734 |
128 | MP0002128_abnormal_blood_circulation | 0.65604456 |
129 | MP0000343_altered_response_to | 0.64961136 |
130 | MP0002138_abnormal_hepatobiliary_system | 0.64636439 |
131 | MP0001666_abnormal_nutrient_absorption | 0.63974366 |
132 | MP0000566_synostosis | 0.63705113 |
133 | MP0005390_skeleton_phenotype | 0.63597616 |
134 | MP0001340_abnormal_eyelid_morphology | 0.62013130 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Atrophic scars (HP:0001075) | 5.58326627 |
2 | Onycholysis (HP:0001806) | 5.38300985 |
3 | Milia (HP:0001056) | 5.29243702 |
4 | Fragile nails (HP:0001808) | 4.05952073 |
5 | Interstitial pulmonary disease (HP:0006530) | 3.84122926 |
6 | Micronodular cirrhosis (HP:0001413) | 3.82268735 |
7 | Right ventricular cardiomyopathy (HP:0011663) | 3.61068446 |
8 | Focal segmental glomerulosclerosis (HP:0000097) | 3.54964405 |
9 | Aortic aneurysm (HP:0004942) | 3.54407977 |
10 | Abnormality of the nasal septum (HP:0000419) | 3.42637745 |
11 | Thick nail (HP:0001805) | 3.42484769 |
12 | Subacute progressive viral hepatitis (HP:0006572) | 3.26843063 |
13 | Arterial tortuosity (HP:0005116) | 3.19264985 |
14 | Follicular hyperkeratosis (HP:0007502) | 3.08792739 |
15 | Flat acetabular roof (HP:0003180) | 3.03730810 |
16 | Deep venous thrombosis (HP:0002625) | 2.98827672 |
17 | Rectal prolapse (HP:0002035) | 2.98501358 |
18 | Natal tooth (HP:0000695) | 2.95197465 |
19 | Nail dystrophy (HP:0008404) | 2.93559956 |
20 | Vascular tortuosity (HP:0004948) | 2.91928277 |
21 | Fragile skin (HP:0001030) | 2.90757803 |
22 | Glomerulosclerosis (HP:0000096) | 2.89945669 |
23 | Abnormality of nail color (HP:0100643) | 2.85265810 |
24 | Abnormality of carpal bone ossification (HP:0006257) | 2.83131446 |
25 | Aortic dissection (HP:0002647) | 2.80358435 |
26 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.76566623 |
27 | Plantar hyperkeratosis (HP:0007556) | 2.76103140 |
28 | Protrusio acetabuli (HP:0003179) | 2.70421633 |
29 | Cerebral aneurysm (HP:0004944) | 2.68644379 |
30 | Ureteral stenosis (HP:0000071) | 2.68138201 |
31 | Ridged nail (HP:0001807) | 2.59709832 |
32 | Palmoplantar hyperkeratosis (HP:0000972) | 2.59385977 |
33 | Esophageal varix (HP:0002040) | 2.55159208 |
34 | Menorrhagia (HP:0000132) | 2.54900788 |
35 | Ureteral obstruction (HP:0006000) | 2.53873425 |
36 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.51123767 |
37 | Radial bowing (HP:0002986) | 2.50719800 |
38 | Abnormal vertebral ossification (HP:0100569) | 2.49662767 |
39 | Hypoplasia of dental enamel (HP:0006297) | 2.48579748 |
40 | Epiphyseal dysplasia (HP:0002656) | 2.47046080 |
41 | Palmar hyperkeratosis (HP:0010765) | 2.46407147 |
42 | Pustule (HP:0200039) | 2.45311077 |
43 | Selective tooth agenesis (HP:0001592) | 2.41570709 |
44 | Pili torti (HP:0003777) | 2.41420437 |
45 | Abnormal ossification of hand bones (HP:0005921) | 2.41174413 |
46 | Shallow orbits (HP:0000586) | 2.39713479 |
47 | Vertebral compression fractures (HP:0002953) | 2.37088437 |
48 | Wormian bones (HP:0002645) | 2.36188529 |
49 | Spinal rigidity (HP:0003306) | 2.33224681 |
50 | Cervical subluxation (HP:0003308) | 2.32244665 |
51 | Hypoalbuminemia (HP:0003073) | 2.31726514 |
52 | Abnormal albumin level (HP:0012116) | 2.31726514 |
53 | Increased density of long bones (HP:0006392) | 2.29106440 |
54 | Advanced eruption of teeth (HP:0006288) | 2.29103050 |
55 | Bronchomalacia (HP:0002780) | 2.28253384 |
56 | Increased mean platelet volume (HP:0011877) | 2.27334624 |
57 | Ankle contracture (HP:0006466) | 2.26587298 |
58 | Coxa vara (HP:0002812) | 2.22382764 |
59 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.21623811 |
60 | Osteolytic defects of the hand bones (HP:0009699) | 2.20275777 |
61 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.20275777 |
62 | Mitral stenosis (HP:0001718) | 2.20177237 |
63 | Abnormal hand bone ossification (HP:0010660) | 2.17690334 |
64 | Lymphangioma (HP:0100764) | 2.15327645 |
65 | Deviation of the thumb (HP:0009603) | 2.14738385 |
66 | Pterygium (HP:0001059) | 2.14455743 |
67 | Abnormal blistering of the skin (HP:0008066) | 2.11601972 |
68 | Curly hair (HP:0002212) | 2.11316580 |
69 | Fused cervical vertebrae (HP:0002949) | 2.10689434 |
70 | Abnormality of oral frenula (HP:0000190) | 2.08802371 |
71 | Small epiphyses (HP:0010585) | 2.08680505 |
72 | Abnormality of dentin (HP:0010299) | 2.07965644 |
73 | Abdominal distention (HP:0003270) | 2.07451162 |
74 | Neonatal death (HP:0003811) | 2.07383037 |
75 | Aneurysm (HP:0002617) | 2.07360266 |
76 | Bowed forearm bones (HP:0003956) | 2.06346838 |
77 | Bowing of the arm (HP:0006488) | 2.06346838 |
78 | Trismus (HP:0000211) | 2.06018591 |
79 | Abnormality of the gastric mucosa (HP:0004295) | 2.05256743 |
80 | Abnormal hair laboratory examination (HP:0003328) | 2.05013527 |
81 | Biliary tract neoplasm (HP:0100574) | 2.03796398 |
82 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.03472560 |
83 | Ankyloglossia (HP:0010296) | 2.02768076 |
84 | Short hallux (HP:0010109) | 2.02440304 |
85 | Short nail (HP:0001799) | 2.02423842 |
86 | Premature rupture of membranes (HP:0001788) | 2.01976773 |
87 | Elbow flexion contracture (HP:0002987) | 1.99896235 |
88 | Xerostomia (HP:0000217) | 1.99423314 |
89 | Abnormal platelet volume (HP:0011876) | 1.98240833 |
90 | Spinal cord compression (HP:0002176) | 1.98174255 |
91 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.97185321 |
92 | Fibular aplasia (HP:0002990) | 1.96946495 |
93 | Bladder diverticulum (HP:0000015) | 1.96178782 |
94 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.95763449 |
95 | Vertebral hypoplasia (HP:0008417) | 1.95763449 |
96 | Aplasia cutis congenita (HP:0001057) | 1.94105375 |
97 | Humeroradial synostosis (HP:0003041) | 1.92490978 |
98 | Synostosis involving the elbow (HP:0003938) | 1.92490978 |
99 | Abnormal foot bone ossification (HP:0010675) | 1.91806252 |
100 | Abnormality of the Achilles tendon (HP:0005109) | 1.91788279 |
101 | Achilles tendon contracture (HP:0001771) | 1.91060154 |
102 | Tarsal synostosis (HP:0008368) | 1.90909132 |
103 | Glucose intolerance (HP:0000833) | 1.89048816 |
104 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.88233774 |
105 | Esophageal atresia (HP:0002032) | 1.88213860 |
106 | Germ cell neoplasia (HP:0100728) | 1.87921432 |
107 | Vertebral arch anomaly (HP:0008438) | 1.86910964 |
108 | Limited elbow extension (HP:0001377) | 1.85576597 |
109 | Mitral valve prolapse (HP:0001634) | 1.84650094 |
110 | Ulnar bowing (HP:0003031) | 1.84200492 |
111 | Oligodontia (HP:0000677) | 1.82106928 |
112 | Gastrointestinal carcinoma (HP:0002672) | 1.82065589 |
113 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.82065589 |
114 | Spondylolisthesis (HP:0003302) | 1.80374178 |
115 | Upper limb amyotrophy (HP:0009129) | 1.80366769 |
116 | Distal upper limb amyotrophy (HP:0007149) | 1.80366769 |
117 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.80272062 |
118 | Hematochezia (HP:0002573) | 1.78574745 |
119 | Short humerus (HP:0005792) | 1.76566821 |
120 | Alopecia of scalp (HP:0002293) | 1.75681037 |
121 | Hypotrichosis (HP:0001006) | 1.74822707 |
122 | Sparse eyelashes (HP:0000653) | 1.73986799 |
123 | Neonatal short-limb short stature (HP:0008921) | 1.73621490 |
124 | Cardiovascular calcification (HP:0011915) | 1.73468408 |
125 | Dilatation of the ascending aorta (HP:0005111) | 1.72921483 |
126 | Broad face (HP:0000283) | 1.72822303 |
127 | Blue sclerae (HP:0000592) | 1.71967112 |
128 | Tibial bowing (HP:0002982) | 1.71807261 |
129 | Spinal cord lesions (HP:0100561) | 1.71667570 |
130 | Syringomyelia (HP:0003396) | 1.71667570 |
131 | Uterine neoplasm (HP:0010784) | 1.70271948 |
132 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.69855902 |
133 | Woolly hair (HP:0002224) | 1.69469238 |
134 | Neurofibrillary tangles (HP:0002185) | 1.69353982 |
135 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.68797607 |
136 | Abnormality of the acetabulum (HP:0003170) | 1.68586269 |
137 | Hypodontia (HP:0000668) | 1.67607773 |
138 | Abnormality of the common coagulation pathway (HP:0010990) | 1.67209535 |
139 | Joint laxity (HP:0001388) | 1.66940076 |
140 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.66737329 |
141 | Short 1st metacarpal (HP:0010034) | 1.66737329 |
142 | Vascular calcification (HP:0004934) | 1.65639410 |
143 | Absent frontal sinuses (HP:0002688) | 1.65336638 |
144 | 11 pairs of ribs (HP:0000878) | 1.62778778 |
145 | Soft skin (HP:0000977) | 1.62284410 |
146 | Protruding ear (HP:0000411) | 1.60629481 |
147 | Popliteal pterygium (HP:0009756) | 1.60576092 |
148 | Blepharitis (HP:0000498) | 1.59722935 |
149 | Overgrowth (HP:0001548) | 1.59674642 |
150 | Tetraparesis (HP:0002273) | 1.58717941 |
151 | Conjugated hyperbilirubinemia (HP:0002908) | 1.58330462 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA2 | 9.57738032 |
2 | MST4 | 4.35816285 |
3 | LATS1 | 2.52975501 |
4 | EPHB1 | 2.48975143 |
5 | EPHB2 | 2.28971768 |
6 | PTK2 | 2.26889697 |
7 | FRK | 2.08993397 |
8 | FER | 2.07104086 |
9 | PAK4 | 2.05705739 |
10 | STK10 | 2.04787175 |
11 | PTK6 | 1.99506400 |
12 | LATS2 | 1.96830901 |
13 | RIPK1 | 1.92816570 |
14 | IRAK3 | 1.87339993 |
15 | LRRK2 | 1.84934259 |
16 | MST1R | 1.79783819 |
17 | NEK9 | 1.75779893 |
18 | MAP3K12 | 1.73947720 |
19 | TTN | 1.68808513 |
20 | RPS6KB2 | 1.63569955 |
21 | TGFBR2 | 1.57151257 |
22 | DMPK | 1.55765291 |
23 | MAP3K2 | 1.39156394 |
24 | FGFR4 | 1.34567414 |
25 | NUAK1 | 1.30754829 |
26 | EPHA3 | 1.29723994 |
27 | STK3 | 1.29710744 |
28 | ICK | 1.28462098 |
29 | TGFBR1 | 1.28280255 |
30 | MET | 1.27119823 |
31 | TRIB3 | 1.26492386 |
32 | PKN2 | 1.24280948 |
33 | STK38 | 1.18807716 |
34 | MAP3K3 | 1.18285157 |
35 | TESK1 | 1.17799575 |
36 | PRKG2 | 1.17372338 |
37 | KDR | 1.14330168 |
38 | STK38L | 1.13164493 |
39 | ARAF | 1.09238575 |
40 | AKT3 | 1.06664130 |
41 | CDK6 | 1.03883204 |
42 | TRPM7 | 1.00613027 |
43 | MAP3K9 | 0.98813506 |
44 | MAP2K2 | 0.98732468 |
45 | EIF2AK1 | 0.97625833 |
46 | LMTK2 | 0.92092515 |
47 | PDGFRA | 0.90938275 |
48 | CSK | 0.90277512 |
49 | TXK | 0.89421420 |
50 | PAK3 | 0.88787033 |
51 | BMX | 0.85640571 |
52 | CDK8 | 0.85516812 |
53 | RPS6KA4 | 0.84638967 |
54 | DDR2 | 0.83883675 |
55 | ERBB3 | 0.81927535 |
56 | FGFR1 | 0.81495930 |
57 | TIE1 | 0.81484640 |
58 | FGFR3 | 0.76518212 |
59 | JAK1 | 0.76345722 |
60 | MAP2K1 | 0.75564679 |
61 | PAK2 | 0.74755636 |
62 | PIM2 | 0.73385776 |
63 | SMG1 | 0.72287544 |
64 | MOS | 0.71082188 |
65 | PIK3CA | 0.68709006 |
66 | PDGFRB | 0.67545911 |
67 | WNK4 | 0.66383631 |
68 | MAP3K8 | 0.66220867 |
69 | DYRK1B | 0.65730069 |
70 | ERBB2 | 0.64324298 |
71 | BRSK2 | 0.62957964 |
72 | MYLK | 0.61336189 |
73 | CHUK | 0.58459413 |
74 | MELK | 0.57452236 |
75 | GSK3A | 0.57307179 |
76 | STK39 | 0.57065583 |
77 | WNK1 | 0.54509560 |
78 | SIK1 | 0.53951290 |
79 | BCR | 0.53482951 |
80 | KSR1 | 0.53296580 |
81 | NEK1 | 0.51964430 |
82 | INSR | 0.51850129 |
83 | STK24 | 0.51372930 |
84 | CDK9 | 0.50485381 |
85 | PBK | 0.48406744 |
86 | ABL2 | 0.47513361 |
87 | PTK2B | 0.46559410 |
88 | CSNK1A1L | 0.46541318 |
89 | ROCK1 | 0.46085432 |
90 | EIF2AK3 | 0.46036983 |
91 | LIMK1 | 0.45640388 |
92 | EGFR | 0.45438227 |
93 | MAP3K10 | 0.44559903 |
94 | PASK | 0.44327598 |
95 | EEF2K | 0.42937765 |
96 | SRC | 0.42903799 |
97 | JAK3 | 0.41789939 |
98 | MAP3K6 | 0.41045918 |
99 | ROCK2 | 0.39886677 |
100 | KSR2 | 0.39552769 |
101 | ITK | 0.39443447 |
102 | ERN1 | 0.38871031 |
103 | SCYL2 | 0.38629858 |
104 | MAP3K7 | 0.38298455 |
105 | NTRK1 | 0.38170361 |
106 | MTOR | 0.37881088 |
107 | PRKCI | 0.37444813 |
108 | ABL1 | 0.35513360 |
109 | MAPKAPK3 | 0.35245344 |
110 | IGF1R | 0.32508017 |
111 | ERBB4 | 0.32185268 |
112 | PRKD2 | 0.31585105 |
113 | CDC42BPA | 0.31546472 |
114 | CDK12 | 0.30690414 |
115 | RPS6KA2 | 0.30400600 |
116 | MAPKAPK2 | 0.30153411 |
117 | ILK | 0.29231188 |
118 | CAMK2B | 0.28741453 |
119 | FGFR2 | 0.27861260 |
120 | RET | 0.27084086 |
121 | NEK6 | 0.26561881 |
122 | AURKB | 0.25248054 |
123 | NME2 | 0.23743445 |
124 | PRKCE | 0.22622138 |
125 | FYN | 0.22533672 |
126 | BMPR1B | 0.22111228 |
127 | SGK3 | 0.21766910 |
128 | MAP3K1 | 0.21557761 |
129 | HIPK2 | 0.21361593 |
130 | FLT3 | 0.20439109 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * ECM-receptor interaction_Homo sapiens_hsa04512 | 3.37249769 |
2 | Adherens junction_Homo sapiens_hsa04520 | 2.84800889 |
3 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 2.69276662 |
4 | * Small cell lung cancer_Homo sapiens_hsa05222 | 2.68256474 |
5 | * Focal adhesion_Homo sapiens_hsa04510 | 2.56219043 |
6 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 2.46865596 |
7 | Viral myocarditis_Homo sapiens_hsa05416 | 2.45237248 |
8 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 2.33810388 |
9 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.22066975 |
10 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 2.06928824 |
11 | * Proteoglycans in cancer_Homo sapiens_hsa05205 | 2.06780752 |
12 | * Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.03166965 |
13 | Tight junction_Homo sapiens_hsa04530 | 1.90493353 |
14 | Bladder cancer_Homo sapiens_hsa05219 | 1.84409803 |
15 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.81926188 |
16 | Amoebiasis_Homo sapiens_hsa05146 | 1.80874054 |
17 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.79306562 |
18 | Malaria_Homo sapiens_hsa05144 | 1.76769035 |
19 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.76217050 |
20 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.71325464 |
21 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.66008399 |
22 | Thyroid cancer_Homo sapiens_hsa05216 | 1.58397639 |
23 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.55458961 |
24 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.54812196 |
25 | * Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.54499814 |
26 | * Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.46589490 |
27 | Shigellosis_Homo sapiens_hsa05131 | 1.46436201 |
28 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.37751823 |
29 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.35548972 |
30 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.31048903 |
31 | * PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.26852903 |
32 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.25543285 |
33 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.23366331 |
34 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.19977325 |
35 | * Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.18874977 |
36 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.14927683 |
37 | Endometrial cancer_Homo sapiens_hsa05213 | 1.13434308 |
38 | Colorectal cancer_Homo sapiens_hsa05210 | 1.12611456 |
39 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.12481698 |
40 | Mineral absorption_Homo sapiens_hsa04978 | 1.11083032 |
41 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.10544729 |
42 | * Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.08958095 |
43 | Salmonella infection_Homo sapiens_hsa05132 | 1.05790865 |
44 | * Pathways in cancer_Homo sapiens_hsa05200 | 1.05233852 |
45 | Prion diseases_Homo sapiens_hsa05020 | 1.04833333 |
46 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.04762687 |
47 | Galactose metabolism_Homo sapiens_hsa00052 | 1.04493246 |
48 | Allograft rejection_Homo sapiens_hsa05330 | 1.03776206 |
49 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.01885189 |
50 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.01880027 |
51 | Apoptosis_Homo sapiens_hsa04210 | 1.00440936 |
52 | * Platelet activation_Homo sapiens_hsa04611 | 0.97403984 |
53 | Leishmaniasis_Homo sapiens_hsa05140 | 0.96397450 |
54 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.96035859 |
55 | Other glycan degradation_Homo sapiens_hsa00511 | 0.94581575 |
56 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.93031004 |
57 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.92538995 |
58 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.92047379 |
59 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.91757531 |
60 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.91531378 |
61 | Prostate cancer_Homo sapiens_hsa05215 | 0.89167706 |
62 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.88687733 |
63 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.88161949 |
64 | HTLV-I infection_Homo sapiens_hsa05166 | 0.86828367 |
65 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.85592744 |
66 | Axon guidance_Homo sapiens_hsa04360 | 0.85182824 |
67 | Pertussis_Homo sapiens_hsa05133 | 0.84523453 |
68 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.83981318 |
69 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.80783856 |
70 | Melanoma_Homo sapiens_hsa05218 | 0.80769532 |
71 | Hepatitis B_Homo sapiens_hsa05161 | 0.80267892 |
72 | Endocytosis_Homo sapiens_hsa04144 | 0.80208391 |
73 | Hepatitis C_Homo sapiens_hsa05160 | 0.79058641 |
74 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.78919917 |
75 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.77733681 |
76 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.76672817 |
77 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.75353825 |
78 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.71883082 |
79 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.69823023 |
80 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.69750451 |
81 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.68785146 |
82 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.67891283 |
83 | Glioma_Homo sapiens_hsa05214 | 0.66907018 |
84 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.66428657 |
85 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.65716279 |
86 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.64374931 |
87 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.64108740 |
88 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.62877176 |
89 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.62171776 |
90 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.61671353 |
91 | Circadian rhythm_Homo sapiens_hsa04710 | 0.58698623 |
92 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.57624238 |
93 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.57597606 |
94 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.57014472 |
95 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.56751271 |
96 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.56581964 |
97 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.56462861 |
98 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.56015823 |
99 | Legionellosis_Homo sapiens_hsa05134 | 0.54694984 |
100 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.53386484 |
101 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.51254385 |
102 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.50765930 |
103 | Measles_Homo sapiens_hsa05162 | 0.50287447 |
104 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.50158862 |
105 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.50064192 |
106 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.49419573 |
107 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.47879340 |
108 | Lysosome_Homo sapiens_hsa04142 | 0.46375955 |
109 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.45476639 |
110 | Melanogenesis_Homo sapiens_hsa04916 | 0.45466311 |
111 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.45385923 |
112 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.45366568 |
113 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.45110153 |
114 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45097440 |
115 | Bile secretion_Homo sapiens_hsa04976 | 0.45059992 |
116 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.44067546 |
117 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.43982346 |
118 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.42059490 |
119 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.41643638 |
120 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.41236623 |
121 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.39944181 |
122 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.39837828 |
123 | Insulin resistance_Homo sapiens_hsa04931 | 0.38924449 |
124 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.38616272 |
125 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.38566748 |
126 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.38210753 |
127 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.38131059 |
128 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.38051095 |
129 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.37632396 |
130 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.37527740 |
131 | Gap junction_Homo sapiens_hsa04540 | 0.36155199 |
132 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.36013462 |
133 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.34882198 |
134 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.33749252 |
135 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.33469832 |
136 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.32782315 |