ITGA5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1blood vessel maturation (GO:0001955)6.82743157
2* cell adhesion mediated by integrin (GO:0033627)4.63615047
3chondrocyte proliferation (GO:0035988)4.59402765
4apoptotic cell clearance (GO:0043277)4.43482161
5endothelium development (GO:0003158)4.40798605
6protein localization to endosome (GO:0036010)4.37897397
7modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.28230718
8modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.28230718
9positive regulation by organism of defense response of other organism involved in symbiotic interact4.28230718
10modulation by symbiont of host immune response (GO:0052553)4.28230718
11positive regulation by symbiont of host defense response (GO:0052509)4.28230718
12modulation by symbiont of host defense response (GO:0052031)4.28230718
13* wound healing, spreading of epidermal cells (GO:0035313)4.17466261
14* endodermal cell differentiation (GO:0035987)4.13083544
15positive regulation of receptor recycling (GO:0001921)4.03703215
16lymphangiogenesis (GO:0001946)4.00888175
17regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.90458399
18positive regulation of endothelial cell apoptotic process (GO:2000353)3.88438269
19regulation of integrin activation (GO:0033623)3.88208723
20collagen fibril organization (GO:0030199)3.77697328
21skin morphogenesis (GO:0043589)3.72710936
22substrate-dependent cell migration (GO:0006929)3.67225232
23vascular endothelial growth factor receptor signaling pathway (GO:0048010)3.61068698
24plasma membrane repair (GO:0001778)3.59746172
25angiogenesis involved in wound healing (GO:0060055)3.53425973
26negative regulation of fatty acid transport (GO:2000192)3.53312360
27vascular endothelial growth factor signaling pathway (GO:0038084)3.49817204
28sprouting angiogenesis (GO:0002040)3.48601377
29low-density lipoprotein particle clearance (GO:0034383)3.47903790
30venous blood vessel morphogenesis (GO:0048845)3.47198705
31protein heterotrimerization (GO:0070208)3.46495061
32regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.45184142
33basement membrane organization (GO:0071711)3.39240304
34negative regulation of adherens junction organization (GO:1903392)3.33764144
35negative regulation of focal adhesion assembly (GO:0051895)3.33764144
36negative regulation of cell junction assembly (GO:1901889)3.33764144
37positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.32895018
38endothelial cell proliferation (GO:0001935)3.32866431
39response to muramyl dipeptide (GO:0032495)3.31823192
40* wound healing, spreading of cells (GO:0044319)3.31742962
41positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.31460275
42positive regulation of p38MAPK cascade (GO:1900745)3.30682039
43positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.28820574
44barbed-end actin filament capping (GO:0051016)3.28612321
45negative regulation of smooth muscle cell migration (GO:0014912)3.25245385
46regulation of cell migration involved in sprouting angiogenesis (GO:0090049)3.22620038
47response to peptidoglycan (GO:0032494)3.21729150
48regulation of dendritic cell antigen processing and presentation (GO:0002604)3.20090246
49mesodermal cell differentiation (GO:0048333)3.19352452
50cellular response to interferon-alpha (GO:0035457)3.18807966
51regulation of membrane protein ectodomain proteolysis (GO:0051043)3.17337443
52cell migration involved in heart development (GO:0060973)3.14886207
53regulation of mononuclear cell migration (GO:0071675)3.12427826
54hypotonic response (GO:0006971)3.10734866
55macrophage activation involved in immune response (GO:0002281)3.09507471
56axon extension involved in axon guidance (GO:0048846)3.09435256
57neuron projection extension involved in neuron projection guidance (GO:1902284)3.09435256
58pinocytosis (GO:0006907)3.06968073
59modulation by symbiont of host cellular process (GO:0044068)3.06912856
60hemidesmosome assembly (GO:0031581)3.06792961
61response to laminar fluid shear stress (GO:0034616)3.03104272
62Golgi transport vesicle coating (GO:0048200)3.02948460
63COPI coating of Golgi vesicle (GO:0048205)3.02948460
64regulation of syncytium formation by plasma membrane fusion (GO:0060142)3.02131443
65positive regulation of blood vessel endothelial cell migration (GO:0043536)2.99881035
66positive regulation of chemokine biosynthetic process (GO:0045080)2.99465433
67myeloid cell homeostasis (GO:0002262)2.99331449
68sequestering of extracellular ligand from receptor (GO:0035581)2.99234373
69negative regulation of blood vessel endothelial cell migration (GO:0043537)2.98570491
70negative regulation of fibrinolysis (GO:0051918)2.98268543
71response to fluid shear stress (GO:0034405)2.98207254
72positive regulation of interleukin-8 secretion (GO:2000484)2.95386226
73positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.93805051
74membrane raft organization (GO:0031579)2.92676245
75morphogenesis of an endothelium (GO:0003159)2.92087329
76endothelial tube morphogenesis (GO:0061154)2.92087329
77positive regulation of endothelial cell migration (GO:0010595)2.91645729
78hyaluronan catabolic process (GO:0030214)2.91246908
79multicellular organismal catabolic process (GO:0044243)2.88650768
80substrate adhesion-dependent cell spreading (GO:0034446)2.87667183
81platelet aggregation (GO:0070527)2.87179054
82negative regulation of nitric-oxide synthase activity (GO:0051001)2.86552776
83regulation of blood vessel endothelial cell migration (GO:0043535)2.85987719
84positive regulation of osteoblast proliferation (GO:0033690)2.85407250
85regulation of tight junction assembly (GO:2000810)2.85292307
86heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.85235293
87positive regulation of interferon-alpha production (GO:0032727)2.83345122
88negative regulation of interleukin-12 production (GO:0032695)2.82794012
89regulation of macrophage cytokine production (GO:0010935)2.81771963
90multicellular organismal metabolic process (GO:0044236)2.79365812
91collagen metabolic process (GO:0032963)2.78654117
92epithelial cell-cell adhesion (GO:0090136)2.76976098
93cell migration involved in sprouting angiogenesis (GO:0002042)2.75468836
94regulation of interferon-beta biosynthetic process (GO:0045357)2.75413263
95neutrophil activation involved in immune response (GO:0002283)2.73972827
96regulation of early endosome to late endosome transport (GO:2000641)2.73923229
97retina vasculature morphogenesis in camera-type eye (GO:0061299)2.73879717
98collagen catabolic process (GO:0030574)2.73192513
99peptide catabolic process (GO:0043171)2.71538956
100regulation of plasminogen activation (GO:0010755)2.71427120
101stress fiber assembly (GO:0043149)2.71087123
102lymph vessel development (GO:0001945)2.69619101
103regulation of interferon-alpha production (GO:0032647)2.69136878
104extracellular fibril organization (GO:0043206)2.68992223
105positive regulation of hemostasis (GO:1900048)2.68850470
106positive regulation of blood coagulation (GO:0030194)2.68850470
107positive regulation of epithelial cell migration (GO:0010634)2.67355899
108fibril organization (GO:0097435)2.67238311
109membrane protein ectodomain proteolysis (GO:0006509)2.67086028
110regulation of cholesterol storage (GO:0010885)2.66314841
111NIK/NF-kappaB signaling (GO:0038061)2.64009273
112natural killer cell mediated cytotoxicity (GO:0042267)2.63174111
113natural killer cell mediated immunity (GO:0002228)2.63174111
114extracellular matrix assembly (GO:0085029)2.63168876
115platelet degranulation (GO:0002576)2.62658453
116viral entry into host cell (GO:0046718)2.60934214
117blood vessel endothelial cell migration (GO:0043534)2.60755632
118response to interferon-alpha (GO:0035455)2.60375569
119tooth mineralization (GO:0034505)2.59501041
120cellular response to vitamin D (GO:0071305)2.58788211
121apoptotic process involved in morphogenesis (GO:0060561)2.57839593
122extracellular matrix disassembly (GO:0022617)2.57687723
123semaphorin-plexin signaling pathway (GO:0071526)2.57243918
124pathway-restricted SMAD protein phosphorylation (GO:0060389)2.56825180
125positive regulation of heat generation (GO:0031652)2.56513824
126positive regulation of fibroblast migration (GO:0010763)2.55488897
127response to host immune response (GO:0052572)2.54955193
128response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.54955193
129T cell apoptotic process (GO:0070231)2.53410226
130multicellular organismal macromolecule metabolic process (GO:0044259)2.53244466
131I-kappaB phosphorylation (GO:0007252)2.53079607
132cortical actin cytoskeleton organization (GO:0030866)2.52573614
133dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.51647761
134peptidyl-proline hydroxylation (GO:0019511)2.51012830
135regulation of metalloenzyme activity (GO:0048552)2.50677964
136* cell-substrate junction assembly (GO:0007044)2.50416910
137cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.49619722
138adherens junction assembly (GO:0034333)2.49549733
139adhesion of symbiont to host cell (GO:0044650)2.49482645
140virion attachment to host cell (GO:0019062)2.49482645
141mRNA transcription (GO:0009299)2.48290693
142regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.48250756
143regulation of transforming growth factor beta1 production (GO:0032908)2.47228682
144regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.46460080
145detection of molecule of bacterial origin (GO:0032490)2.46174380
146positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511)2.46151310
147cellular response to vitamin (GO:0071295)2.45881169
148positive regulation of natural killer cell differentiation (GO:0032825)2.45859244
149chondroitin sulfate biosynthetic process (GO:0030206)2.45579171
150positive regulation of coagulation (GO:0050820)2.45436572
151response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.44647766
152response to host (GO:0075136)2.44647766
153response to host defenses (GO:0052200)2.44647766
154regulation of fibroblast migration (GO:0010762)2.44613833
155endothelial cell morphogenesis (GO:0001886)2.44593715
156negative regulation of chondrocyte differentiation (GO:0032331)2.44511327

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EGR1_19374776_ChIP-ChIP_THP-1_Human4.23021077
2TRIM28_21343339_ChIP-Seq_HEK293_Human4.13623490
3* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.99888067
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.96928071
5BP1_19119308_ChIP-ChIP_Hs578T_Human3.11341681
6* TP63_17297297_ChIP-ChIP_HaCaT_Human2.98989335
7RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.84058931
8* IRF8_21731497_ChIP-ChIP_J774_Mouse2.75360193
9* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.61780634
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.61667896
11RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.57190014
12* ELK3_25401928_ChIP-Seq_HUVEC_Human2.52030924
13TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.42979953
14SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.41247481
15Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.39974174
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.32599359
17NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.32446967
18CLOCK_20551151_ChIP-Seq_293T_Human2.26992870
19* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.16925270
20* IRF8_27001747_Chip-Seq_BMDM_Mouse2.14067163
21SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.96688577
22PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.93696941
23* HIF1A_21447827_ChIP-Seq_MCF-7_Human1.93302659
24STAT6_21828071_ChIP-Seq_BEAS2B_Human1.90783367
25NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.88755751
26BRD4_27068464_Chip-Seq_AML-cells_Mouse1.86605310
27SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.86273062
28SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.86273062
29MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.72688717
30* BRD4_25478319_ChIP-Seq_HGPS_Human1.69999897
31GATA2_21666600_ChIP-Seq_HMVEC_Human1.68241507
32STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.68206644
33KDM2B_26808549_Chip-Seq_SUP-B15_Human1.63373855
34* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.62118793
35CJUN_26792858_Chip-Seq_BT549_Human1.61607840
36FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.60996231
37IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.60669908
38VDR_21846776_ChIP-Seq_THP-1_Human1.60233788
39* ATF3_27146783_Chip-Seq_COLON_Human1.59877181
40STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.58166926
41FOXM1_23109430_ChIP-Seq_U2OS_Human1.57998769
42SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.56630559
43KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.55105156
44ESR1_21235772_ChIP-Seq_MCF-7_Human1.53475550
45PPAR_26484153_Chip-Seq_NCI-H1993_Human1.51438069
46VDR_24763502_ChIP-Seq_THP-1_Human1.50401505
47P300_27058665_Chip-Seq_ZR-75-30cells_Human1.48201487
48CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.48154961
49JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.45480242
50SPI1_23127762_ChIP-Seq_K562_Human1.42442589
51KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.41277401
52TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39314702
53PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.38258531
54TP53_22127205_ChIP-Seq_IMR90_Human1.36093672
55KDM2B_26808549_Chip-Seq_DND41_Human1.36004596
56* ESR2_21235772_ChIP-Seq_MCF-7_Human1.35726269
57JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.34551718
58FOXO3_23340844_ChIP-Seq_DLD1_Human1.34379626
59RACK7_27058665_Chip-Seq_MCF-7_Human1.34050465
60PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.32936723
61TCF7_22412390_ChIP-Seq_EML_Mouse1.32497687
62UBF1/2_26484160_Chip-Seq_HMECs_Human1.31077760
63* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.30798704
64KDM2B_26808549_Chip-Seq_K562_Human1.27639159
65GATA1_19941826_ChIP-Seq_K562_Human1.26909943
66SOX9_24532713_ChIP-Seq_HFSC_Mouse1.26828826
67EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.26632041
68NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.26516189
69CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.25320861
70SALL4_18804426_ChIP-ChIP_XEN_Mouse1.24470638
71THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.24255549
72STAT3_1855785_ChIP-Seq_MESCs_Mouse1.22946330
73NFIB_24661679_ChIP-Seq_LUNG_Mouse1.22941754
74MAF_26560356_Chip-Seq_TH1_Human1.22596768
75FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.22359392
76SMAD_19615063_ChIP-ChIP_OVARY_Human1.21661908
77STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.20224348
78WT1_19549856_ChIP-ChIP_CCG9911_Human1.19601952
79LXR_22292898_ChIP-Seq_THP-1_Human1.18264336
80ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.18021878
81NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.17834088
82VDR_24787735_ChIP-Seq_THP-1_Human1.17364475
83KDM2B_26808549_Chip-Seq_JURKAT_Human1.16449661
84KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.15995372
85MYC_22102868_ChIP-Seq_BL_Human1.15681672
86SMC1_22415368_ChIP-Seq_MEFs_Mouse1.15651752
87NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.14786844
88ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.12240782
89PU_27001747_Chip-Seq_BMDM_Mouse1.11112505
90RUNX1_22412390_ChIP-Seq_EML_Mouse1.10377215
91P63_26484246_Chip-Seq_KERATINOCYTES_Human1.09900609
92TBX20_22328084_ChIP-Seq_HEART_Mouse1.09028373
93TBX20_22080862_ChIP-Seq_HEART_Mouse1.09028373
94TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.08646776
95HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.07413303
96TFEB_21752829_ChIP-Seq_HELA_Human1.07372318
97ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.07346231
98TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06548894
99SMC3_22415368_ChIP-Seq_MEFs_Mouse1.06166514
100NCOR1_26117541_ChIP-Seq_K562_Human1.06056000
101* SOX2_20726797_ChIP-Seq_SW620_Human1.05407937
102SPI1_23547873_ChIP-Seq_NB4_Human1.05186298
103STAT4_19710469_ChIP-ChIP_TH1__Mouse1.04662849
104* TP53_23651856_ChIP-Seq_MEFs_Mouse1.04246099
105NRF2_20460467_ChIP-Seq_MEFs_Mouse1.03656664
106NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.03656664
107EP300_21415370_ChIP-Seq_HL-1_Mouse1.03600289
108* UTX_26944678_Chip-Seq_JUKART_Human1.03399043
109* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02489211
110TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01502966
111ZNF263_19887448_ChIP-Seq_K562_Human1.01459627
112SCL_19346495_ChIP-Seq_HPC-7_Human1.01069343
113* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.00208135
114TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.98896705
115* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.97263012
116VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.95774403
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95154178
118CTCF_27219007_Chip-Seq_ERYTHROID_Human0.90721867
119KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.89772403
120SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.89525465

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.48004543
2MP0003705_abnormal_hypodermis_morpholog3.78779861
3MP0003279_aneurysm3.43723173
4MP0005275_abnormal_skin_tensile2.94790877
5MP0010352_gastrointestinal_tract_polyps2.80296561
6* MP0003566_abnormal_cell_adhesion2.75569628
7MP0001958_emphysema2.54494833
8MP0005023_abnormal_wound_healing2.39197259
9MP0003091_abnormal_cell_migration2.33779964
10MP0003303_peritoneal_inflammation2.30052826
11MP0009278_abnormal_bone_marrow2.25848305
12MP0005257_abnormal_intraocular_pressure2.25713799
13MP0005503_abnormal_tendon_morphology2.21731726
14MP0004272_abnormal_basement_membrane2.19058116
15MP0005623_abnormal_meninges_morphology2.13774055
16MP0000569_abnormal_digit_pigmentation2.12052522
17MP0006054_spinal_hemorrhage2.02010282
18MP0003436_decreased_susceptibility_to1.88205095
19MP0005595_abnormal_vascular_smooth1.82559061
20MP0003191_abnormal_cellular_cholesterol1.77531949
21MP0000767_abnormal_smooth_muscle1.70252755
22MP0000750_abnormal_muscle_regeneration1.65087355
23MP0003300_gastrointestinal_ulcer1.64460388
24MP0003448_altered_tumor_morphology1.64079090
25MP0010368_abnormal_lymphatic_system1.61047275
26MP0005058_abnormal_lysosome_morphology1.58055213
27MP0004510_myositis1.57284939
28MP0000733_abnormal_muscle_development1.56503848
29MP0005076_abnormal_cell_differentiation1.54739246
30MP0001533_abnormal_skeleton_physiology1.48556422
31MP0001243_abnormal_dermal_layer1.48084493
32MP0000343_altered_response_to1.45934290
33MP0002295_abnormal_pulmonary_circulatio1.40260706
34MP0002060_abnormal_skin_morphology1.36506063
35MP0002419_abnormal_innate_immunity1.34680611
36MP0004947_skin_inflammation1.34645726
37MP0000465_gastrointestinal_hemorrhage1.34224673
38MP0000858_altered_metastatic_potential1.33671289
39MP0001849_ear_inflammation1.28592276
40MP0005167_abnormal_blood-brain_barrier1.26548792
41MP0005397_hematopoietic_system_phenotyp1.25099290
42MP0001545_abnormal_hematopoietic_system1.25099290
43MP0004084_abnormal_cardiac_muscle1.24736291
44MP0005390_skeleton_phenotype1.23911443
45MP0005165_increased_susceptibility_to1.20799797
46MP0003828_pulmonary_edema1.19707812
47MP0005508_abnormal_skeleton_morphology1.19421090
48MP0001915_intracranial_hemorrhage1.19064587
49MP0003172_abnormal_lysosome_physiology1.18170366
50MP0002998_abnormal_bone_remodeling1.18104276
51MP0005451_abnormal_body_composition1.17293429
52MP0008260_abnormal_autophagy1.12700354
53MP0001879_abnormal_lymphatic_vessel1.11981721
54MP0009785_altered_susceptibility_to1.11274816
55MP0010030_abnormal_orbit_morphology1.11054569
56MP0004808_abnormal_hematopoietic_stem1.10869592
57MP0008004_abnormal_stomach_pH1.10002038
58MP0009840_abnormal_foam_cell1.09455995
59MP0005464_abnormal_platelet_physiology1.07480281
60MP0001853_heart_inflammation1.07335664
61MP0000685_abnormal_immune_system1.07211009
62MP0004233_abnormal_muscle_weight1.06555572
63MP0001348_abnormal_lacrimal_gland1.06231399
64MP0010307_abnormal_tumor_latency1.03505122
65MP0004858_abnormal_nervous_system1.00929957
66MP0002128_abnormal_blood_circulation1.00857638
67MP0002877_abnormal_melanocyte_morpholog1.00774785
68MP0005164_abnormal_response_to1.00606350
69MP0001542_abnormal_bone_strength1.00164359
70MP0009384_cardiac_valve_regurgitation1.00067175
71MP0002933_joint_inflammation0.99495306
72MP0010630_abnormal_cardiac_muscle0.99009768
73* MP0001614_abnormal_blood_vessel0.97094784
74MP0001835_abnormal_antigen_presentation0.96320813
75MP0003045_fibrosis0.95600655
76MP0005000_abnormal_immune_tolerance0.95322483
77MP0009053_abnormal_anal_canal0.94724852
78MP0008775_abnormal_heart_ventricle0.94388723
79MP0002332_abnormal_exercise_endurance0.93268143
80MP0002168_other_aberrant_phenotype0.91410172
81MP0000249_abnormal_blood_vessel0.90918936
82MP0005025_abnormal_response_to0.90875508
83MP0004883_abnormal_blood_vessel0.90854838
84MP0004087_abnormal_muscle_fiber0.90285118
85MP0006138_congestive_heart_failure0.89885292
86MP0002452_abnormal_antigen_presenting0.89737071
87MP0002405_respiratory_system_inflammati0.89132685
88MP0000751_myopathy0.88335009
89* MP0002925_abnormal_cardiovascular_devel0.84697035
90MP0009764_decreased_sensitivity_to0.84386040
91MP0002138_abnormal_hepatobiliary_system0.84229568
92MP0002148_abnormal_hypersensitivity_rea0.81313509
93MP0003453_abnormal_keratinocyte_physiol0.81308626
94MP0005197_abnormal_uvea_morphology0.80665871
95MP0002896_abnormal_bone_mineralization0.80146276
96MP0005387_immune_system_phenotype0.79430814
97MP0001790_abnormal_immune_system0.79430814
98MP0006082_CNS_inflammation0.78970030
99MP0003795_abnormal_bone_structure0.78487817
100MP0003950_abnormal_plasma_membrane0.78318496
101MP0000678_abnormal_parathyroid_gland0.77437780
102MP0009333_abnormal_splenocyte_physiolog0.76641094
103MP0003724_increased_susceptibility_to0.76153419
104MP0000749_muscle_degeneration0.75624140
105MP0001175_abnormal_lung_morphology0.74870050
106MP0000013_abnormal_adipose_tissue0.72597209
107MP0000604_amyloidosis0.72493509
108* MP0005621_abnormal_cell_physiology0.72289983
109MP0002113_abnormal_skeleton_development0.71830303
110MP0009697_abnormal_copulation0.71806304
111MP0003385_abnormal_body_wall0.71464017
112MP0002282_abnormal_trachea_morphology0.69531682
113MP0005385_cardiovascular_system_phenoty0.68783378
114MP0001544_abnormal_cardiovascular_syste0.68783378
115MP0005409_darkened_coat_color0.67581761
116MP0000266_abnormal_heart_morphology0.67385068
117MP0004036_abnormal_muscle_relaxation0.67274665
118MP0002723_abnormal_immune_serum0.67102318
119MP0003941_abnormal_skin_development0.66421056
120MP0003075_altered_response_to0.64873449
121MP0009763_increased_sensitivity_to0.64305412
122MP0001845_abnormal_inflammatory_respons0.64160755
123MP0002133_abnormal_respiratory_system0.63707658
124MP0005388_respiratory_system_phenotype0.63707658
125MP0002127_abnormal_cardiovascular_syste0.63268825
126MP0000003_abnormal_adipose_tissue0.62585440
127MP0000759_abnormal_skeletal_muscle0.60850511

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)6.71398317
2Protrusio acetabuli (HP:0003179)6.58322783
3Peritonitis (HP:0002586)4.74788305
4Cerebral aneurysm (HP:0004944)4.38434922
5Aortic dissection (HP:0002647)4.23904641
6Shallow orbits (HP:0000586)3.69670029
7Vertebral compression fractures (HP:0002953)3.61097649
8Aortic aneurysm (HP:0004942)3.61028644
9Cervical subluxation (HP:0003308)3.58671549
10Dilatation of the ascending aorta (HP:0005111)3.55853011
11Ankle contracture (HP:0006466)3.49570052
12Increased connective tissue (HP:0009025)3.49359678
13Atrophic scars (HP:0001075)3.48779910
14Spontaneous hematomas (HP:0007420)3.27972953
15Soft skin (HP:0000977)3.20350937
16Fragile skin (HP:0001030)3.14237219
17Genu recurvatum (HP:0002816)2.99380521
18Abnormality of glycolipid metabolism (HP:0010969)2.95030766
19Abnormality of liposaccharide metabolism (HP:0010968)2.95030766
20Abnormality of glycosphingolipid metabolism (HP:0004343)2.95030766
21Bladder diverticulum (HP:0000015)2.92487640
22Polycythemia (HP:0001901)2.90702093
23Mitral valve prolapse (HP:0001634)2.90108283
24Blue sclerae (HP:0000592)2.89451600
25Osteolytic defects of the hand bones (HP:0009699)2.87531884
26Osteolytic defects of the phalanges of the hand (HP:0009771)2.87531884
27Biconcave vertebral bodies (HP:0004586)2.85819466
28Ankyloglossia (HP:0010296)2.83880341
29Spinal rigidity (HP:0003306)2.82524802
30Follicular hyperkeratosis (HP:0007502)2.82067298
31Abnormality of oral frenula (HP:0000190)2.75315186
32Wormian bones (HP:0002645)2.74275439
33Type 1 muscle fiber predominance (HP:0003803)2.69689019
34Distal upper limb amyotrophy (HP:0007149)2.67779000
35Upper limb amyotrophy (HP:0009129)2.67779000
36Distal lower limb amyotrophy (HP:0008944)2.66779810
37Increased density of long bones (HP:0006392)2.65294102
38Abnormality of dentin (HP:0010299)2.64067016
39Elevated erythrocyte sedimentation rate (HP:0003565)2.63770246
40Broad metatarsal (HP:0001783)2.58002713
41Wrist flexion contracture (HP:0001239)2.55948967
42Ulnar bowing (HP:0003031)2.52345508
43Difficulty climbing stairs (HP:0003551)2.51577695
44Esophageal varix (HP:0002040)2.49661598
45Aneurysm (HP:0002617)2.48763013
46Disproportionate tall stature (HP:0001519)2.47291405
47Radial bowing (HP:0002986)2.46902242
48Abnormality of the peritoneum (HP:0002585)2.45900597
49Abnormality of the acetabulum (HP:0003170)2.40798032
50Short nail (HP:0001799)2.37979380
51Camptodactyly of toe (HP:0001836)2.30864658
52Conjunctival telangiectasia (HP:0000524)2.27316657
53Recurrent abscess formation (HP:0002722)2.27013150
54Dysostosis multiplex (HP:0000943)2.21801970
55Coxa vara (HP:0002812)2.21518201
56Scapular winging (HP:0003691)2.21507335
57Myocardial infarction (HP:0001658)2.20047424
58Elbow flexion contracture (HP:0002987)2.16865013
59Overgrowth (HP:0001548)2.16168887
60Mitral stenosis (HP:0001718)2.12413100
61Muscle fiber splitting (HP:0003555)2.12330498
62Abnormal delivery (HP:0001787)2.11841003
63Ectopia lentis (HP:0001083)2.11671966
64Neonatal short-limb short stature (HP:0008921)2.11116219
65Increased cerebral lipofuscin (HP:0011813)2.11098128
66Hematochezia (HP:0002573)2.10852184
67Aortic valve stenosis (HP:0001650)2.10589938
68Syringomyelia (HP:0003396)2.10181273
69Spinal cord lesions (HP:0100561)2.10181273
70Recurrent bacterial skin infections (HP:0005406)2.09965627
71Abnormality of polysaccharide metabolism (HP:0011012)2.09331334
72Abnormality of glycosaminoglycan metabolism (HP:0004371)2.09331334
73Abnormality of mucopolysaccharide metabolism (HP:0011020)2.09331334
74Aortic regurgitation (HP:0001659)2.08623596
75Broad face (HP:0000283)2.08563493
76Abnormality of the vasculature of the conjunctiva (HP:0008054)2.08562050
77Mitral regurgitation (HP:0001653)2.08014072
78Abnormality of the calcaneus (HP:0008364)2.08008809
79Vascular tortuosity (HP:0004948)2.07377728
80Long toe (HP:0010511)2.07375912
81Joint contractures involving the joints of the feet (HP:0100492)2.06509488
82Flexion contracture of toe (HP:0005830)2.06509488
83Mucopolysacchariduria (HP:0008155)2.06296076
84Urinary glycosaminoglycan excretion (HP:0003541)2.06296076
85Bowed forearm bones (HP:0003956)2.04018528
86Bowing of the arm (HP:0006488)2.04018528
87Nonimmune hydrops fetalis (HP:0001790)2.02863181
88Frequent falls (HP:0002359)2.02077989
89Bowel diverticulosis (HP:0005222)2.01055279
90Hand muscle atrophy (HP:0009130)1.99838823
91Increased mean platelet volume (HP:0011877)1.99790927
92Increased variability in muscle fiber diameter (HP:0003557)1.98000607
93Generalized amyotrophy (HP:0003700)1.97766267
94Persistence of primary teeth (HP:0006335)1.97123407
95Thin bony cortex (HP:0002753)1.96641045
96Thick nail (HP:0001805)1.94395467
97Tibial bowing (HP:0002982)1.93126216
98Eczematoid dermatitis (HP:0000976)1.92611064
99Lower limb amyotrophy (HP:0007210)1.91203915
100Right ventricular cardiomyopathy (HP:0011663)1.91179527
101Axonal loss (HP:0003447)1.89806778
102Abnormality of skeletal muscle fiber size (HP:0012084)1.88604925
103Achilles tendon contracture (HP:0001771)1.88501578
104Fused cervical vertebrae (HP:0002949)1.88193514
105Abnormality of the nasal mucosa (HP:0000433)1.87718283
106Spondylolisthesis (HP:0003302)1.87377201
107Ovoid vertebral bodies (HP:0003300)1.87203840
108Round ear (HP:0100830)1.86621950
109Hyperextensible skin (HP:0000974)1.86532496
110Absent frontal sinuses (HP:0002688)1.83025458
111Arterial tortuosity (HP:0005116)1.82034498
112Reduced subcutaneous adipose tissue (HP:0003758)1.80585648
113Abnormal platelet volume (HP:0011876)1.80497945
114Mildly elevated creatine phosphokinase (HP:0008180)1.79460158
115Cerebral hemorrhage (HP:0001342)1.79358371
116Mesomelia (HP:0003027)1.78872603
117Flat acetabular roof (HP:0003180)1.78844081
118Slender build (HP:0001533)1.78037396
119Turricephaly (HP:0000262)1.77747747
120Asymmetric septal hypertrophy (HP:0001670)1.77591419
121Joint laxity (HP:0001388)1.76699225
122Natal tooth (HP:0000695)1.76630252
123Joint stiffness (HP:0001387)1.75954078
124Venous abnormality (HP:0002624)1.74573405
125Cardiovascular calcification (HP:0011915)1.73972061
126Infantile muscular hypotonia (HP:0008947)1.72683679
127Nuclear cataract (HP:0100018)1.72335685
128Menorrhagia (HP:0000132)1.71223834
129Bruising susceptibility (HP:0000978)1.71209043
130Distal lower limb muscle weakness (HP:0009053)1.69992141
131Tetraparesis (HP:0002273)1.69687732
132Hyporeflexia of lower limbs (HP:0002600)1.69657631
133Increased neuronal autofluorescent lipopigment (HP:0002074)1.69119795
134Stomatitis (HP:0010280)1.66399726

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.82300587
2TRIB33.63251322
3ERN13.09980282
4PKN22.93059096
5DDR22.21958893
6TBK12.16950966
7PDGFRA2.04860075
8RPS6KA41.97435573
9RIPK11.89983185
10PTK61.89361824
11MAP3K141.87250059
12PAK21.81533984
13NTRK11.78956291
14BMX1.74814345
15LATS21.73371223
16TESK11.70610769
17TRPM71.65520230
18MAP3K101.62388075
19PTK21.59656188
20KIT1.59243465
21PIM21.59238046
22MAP2K31.57060430
23EPHA21.54923623
24KDR1.54802510
25IRAK31.54371783
26PIK3CG1.53800271
27CDK121.52741560
28PRPF4B1.51080315
29LATS11.48432699
30PAK41.44334613
31MAP3K31.44308194
32DMPK1.43347862
33TGFBR21.39124311
34PTK2B1.34416896
35TYK21.34196331
36NME21.31610963
37LRRK21.30337517
38JAK31.21227163
39EPHB11.18073723
40CDC42BPA1.16627055
41FES1.16012058
42STK101.12424418
43PRKD21.09573487
44IKBKB1.07538480
45STK31.05189437
46STK381.03131130
47NEK91.02781683
48MOS1.01898117
49MTOR1.00763442
50MYLK0.98781949
51LIMK10.94735405
52DAPK30.94426876
53TESK20.92502839
54SIK10.91573389
55JAK10.89413261
56HCK0.89302558
57MAP3K110.88269093
58CSK0.88187401
59PDGFRB0.87253527
60ICK0.87184429
61ARAF0.85933419
62CHUK0.85004895
63PRKG20.84437552
64RPS6KA20.82704615
65IKBKE0.81352294
66TAOK20.81314985
67MAP3K80.80006450
68KSR20.79927372
69CDK60.79850121
70MAPKAPK30.78613338
71TEC0.77898890
72FLT30.75597041
73MAP3K130.75078405
74ABL20.74736721
75ILK0.74164594
76EPHB20.73813575
77MAP3K60.72908165
78TAOK10.71999034
79RIPK40.70935263
80ROCK20.69350751
81SMG10.68873243
82MET0.68839602
83ZAP700.68549402
84PAK60.68322507
85SCYL20.65732585
86MAP3K10.65044378
87EGFR0.64306891
88CLK10.64141985
89CAMK1D0.62646919
90PAK30.62533291
91MAPK70.62341118
92EEF2K0.62115778
93PAK10.58209947
94ERBB40.57285450
95TGFBR10.56315363
96TIE10.55430202
97BLK0.53434091
98PIK3CA0.52564033
99PIM10.51517345
100INSR0.51388815
101MAP3K50.51220219
102FGFR40.50958705
103MAPKAPK20.49082915
104ROCK10.48942402
105PDPK10.48622671
106ABL10.48576108
107PRKD30.48526424
108FER0.48315832
109FGFR10.47413676
110ALK0.46608440
111GRK70.46480737
112GSK3A0.46384301
113TAOK30.45562240
114CSF1R0.44923779
115MAP4K10.44555923
116NEK20.44020627
117FGR0.43221679
118PRKD10.43070074
119EPHA30.43023920
120IRAK40.43019363
121LMTK20.41002314
122SRC0.40514618
123MAP2K10.40436416
124RPS6KC10.39283326
125RPS6KL10.39283326
126MARK20.35482059
127KSR10.32012053

Predicted pathways (KEGG)

RankGene SetZ-score
1Malaria_Homo sapiens_hsa051442.74641780
2Leishmaniasis_Homo sapiens_hsa051402.51061430
3* ECM-receptor interaction_Homo sapiens_hsa045122.49326664
4* Focal adhesion_Homo sapiens_hsa045102.20511325
5Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.17273380
6Amoebiasis_Homo sapiens_hsa051462.17013395
7TNF signaling pathway_Homo sapiens_hsa046682.05881995
8AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.04725424
9Small cell lung cancer_Homo sapiens_hsa052221.98405599
10Osteoclast differentiation_Homo sapiens_hsa043801.92831588
11* Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.92059084
12* Proteoglycans in cancer_Homo sapiens_hsa052051.85128239
13Toll-like receptor signaling pathway_Homo sapiens_hsa046201.84672926
14NF-kappa B signaling pathway_Homo sapiens_hsa040641.78597242
15Chronic myeloid leukemia_Homo sapiens_hsa052201.72219753
16Toxoplasmosis_Homo sapiens_hsa051451.68862118
17Legionellosis_Homo sapiens_hsa051341.67011332
18* Shigellosis_Homo sapiens_hsa051311.65377299
19Bladder cancer_Homo sapiens_hsa052191.62968663
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.61479880
21Viral myocarditis_Homo sapiens_hsa054161.60346088
22Leukocyte transendothelial migration_Homo sapiens_hsa046701.59966125
23Apoptosis_Homo sapiens_hsa042101.59916203
24Staphylococcus aureus infection_Homo sapiens_hsa051501.56507052
25* Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.53987458
26Tuberculosis_Homo sapiens_hsa051521.47885654
27* Pertussis_Homo sapiens_hsa051331.46192684
28* MicroRNAs in cancer_Homo sapiens_hsa052061.45508196
29Adherens junction_Homo sapiens_hsa045201.44109708
30Salmonella infection_Homo sapiens_hsa051321.44061849
31Glycosaminoglycan degradation_Homo sapiens_hsa005311.42170767
32* Dilated cardiomyopathy_Homo sapiens_hsa054141.40295958
33p53 signaling pathway_Homo sapiens_hsa041151.32716119
34* Phagosome_Homo sapiens_hsa041451.32187521
35* Regulation of actin cytoskeleton_Homo sapiens_hsa048101.30374585
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.28557006
37Measles_Homo sapiens_hsa051621.27380965
38Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.26258397
39Influenza A_Homo sapiens_hsa051641.26237822
40Lysosome_Homo sapiens_hsa041421.25504863
41Hepatitis B_Homo sapiens_hsa051611.18185917
42HIF-1 signaling pathway_Homo sapiens_hsa040661.14413960
43Rheumatoid arthritis_Homo sapiens_hsa053231.12402639
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.11516898
45Pancreatic cancer_Homo sapiens_hsa052121.10456619
46* Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.10094821
47Platelet activation_Homo sapiens_hsa046111.07731444
48B cell receptor signaling pathway_Homo sapiens_hsa046621.02478630
49TGF-beta signaling pathway_Homo sapiens_hsa043501.02123299
50Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.01022724
51* PI3K-Akt signaling pathway_Homo sapiens_hsa041511.00964737
52RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.97962094
53Caffeine metabolism_Homo sapiens_hsa002320.96481666
54Complement and coagulation cascades_Homo sapiens_hsa046100.96441406
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.92313468
56Phospholipase D signaling pathway_Homo sapiens_hsa040720.89358312
57Acute myeloid leukemia_Homo sapiens_hsa052210.89082929
58Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.88801336
59HTLV-I infection_Homo sapiens_hsa051660.86200255
60Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.86108891
61VEGF signaling pathway_Homo sapiens_hsa043700.85981669
62Melanoma_Homo sapiens_hsa052180.85143788
63Adipocytokine signaling pathway_Homo sapiens_hsa049200.84436587
64Sphingolipid signaling pathway_Homo sapiens_hsa040710.83795887
65Viral carcinogenesis_Homo sapiens_hsa052030.83653751
66Vibrio cholerae infection_Homo sapiens_hsa051100.81329004
67Protein digestion and absorption_Homo sapiens_hsa049740.80708549
68Herpes simplex infection_Homo sapiens_hsa051680.77708929
69Jak-STAT signaling pathway_Homo sapiens_hsa046300.77460390
70Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.77023285
71Insulin resistance_Homo sapiens_hsa049310.75698186
72Hepatitis C_Homo sapiens_hsa051600.75254765
73Graft-versus-host disease_Homo sapiens_hsa053320.74661673
74Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73461638
75Galactose metabolism_Homo sapiens_hsa000520.73230506
76Prostate cancer_Homo sapiens_hsa052150.72973144
77Notch signaling pathway_Homo sapiens_hsa043300.72944187
78African trypanosomiasis_Homo sapiens_hsa051430.72651600
79Rap1 signaling pathway_Homo sapiens_hsa040150.71994681
80GnRH signaling pathway_Homo sapiens_hsa049120.70831707
81Antigen processing and presentation_Homo sapiens_hsa046120.70813997
82Central carbon metabolism in cancer_Homo sapiens_hsa052300.70700085
83* Hematopoietic cell lineage_Homo sapiens_hsa046400.70311533
84Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.70115840
85Renal cell carcinoma_Homo sapiens_hsa052110.68679284
86Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68158644
87Estrogen signaling pathway_Homo sapiens_hsa049150.66270170
88Glioma_Homo sapiens_hsa052140.65992833
89mTOR signaling pathway_Homo sapiens_hsa041500.65947922
90One carbon pool by folate_Homo sapiens_hsa006700.65079283
91Hippo signaling pathway_Homo sapiens_hsa043900.64776265
92Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.64704194
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64342098
94Allograft rejection_Homo sapiens_hsa053300.62654981
95Epstein-Barr virus infection_Homo sapiens_hsa051690.62602132
96Pathways in cancer_Homo sapiens_hsa052000.62060585
97Non-small cell lung cancer_Homo sapiens_hsa052230.61377516
98N-Glycan biosynthesis_Homo sapiens_hsa005100.58392436
99Other glycan degradation_Homo sapiens_hsa005110.57966255
100Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.56312094
101Ras signaling pathway_Homo sapiens_hsa040140.54745612
102Chemokine signaling pathway_Homo sapiens_hsa040620.54666613
103Pentose phosphate pathway_Homo sapiens_hsa000300.54542307
104Thyroid cancer_Homo sapiens_hsa052160.53149804
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.52694212
106Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52229751
107Axon guidance_Homo sapiens_hsa043600.51589483
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.50956957
109Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.50233254
110Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.50214727
111Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50024750
112Endometrial cancer_Homo sapiens_hsa052130.49954683
113Colorectal cancer_Homo sapiens_hsa052100.49629889
114Dorso-ventral axis formation_Homo sapiens_hsa043200.48798680
115Prolactin signaling pathway_Homo sapiens_hsa049170.48769238
116Sphingolipid metabolism_Homo sapiens_hsa006000.48540179
117FoxO signaling pathway_Homo sapiens_hsa040680.47106090
118Asthma_Homo sapiens_hsa053100.45867073
119Endocytosis_Homo sapiens_hsa041440.40821564
120Prion diseases_Homo sapiens_hsa050200.40272443
121Transcriptional misregulation in cancer_Homo sapiens_hsa052020.38298180
122Lysine degradation_Homo sapiens_hsa003100.37157618
123Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.36078849

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