Rank | Gene Set | Z-score |
---|---|---|
1 | glomerular visceral epithelial cell development (GO:0072015) | 7.51521967 |
2 | glomerular basement membrane development (GO:0032836) | 7.14516296 |
3 | glomerular epithelial cell development (GO:0072310) | 6.68717247 |
4 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 5.18550588 |
5 | axon extension involved in axon guidance (GO:0048846) | 5.18550588 |
6 | glomerulus development (GO:0032835) | 5.04907129 |
7 | vascular endothelial growth factor signaling pathway (GO:0038084) | 4.70146909 |
8 | metanephric mesenchyme development (GO:0072075) | 4.61130766 |
9 | renal filtration (GO:0097205) | 4.54419433 |
10 | kidney mesenchyme development (GO:0072074) | 4.37208217 |
11 | lymph vessel development (GO:0001945) | 4.29564458 |
12 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 4.26529606 |
13 | glomerular filtration (GO:0003094) | 4.24570133 |
14 | cell migration involved in sprouting angiogenesis (GO:0002042) | 4.20761182 |
15 | lymphangiogenesis (GO:0001946) | 4.08591023 |
16 | negative regulation of axon guidance (GO:1902668) | 4.07869977 |
17 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 4.06423779 |
18 | cell adhesion mediated by integrin (GO:0033627) | 4.04662909 |
19 | collagen fibril organization (GO:0030199) | 4.03302180 |
20 | regulation of axon guidance (GO:1902667) | 3.99328657 |
21 | regulation of axon extension involved in axon guidance (GO:0048841) | 3.97322096 |
22 | chondrocyte proliferation (GO:0035988) | 3.87171216 |
23 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.71326693 |
24 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.49448931 |
25 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 3.46504655 |
26 | surfactant homeostasis (GO:0043129) | 3.41601668 |
27 | coronary vasculature morphogenesis (GO:0060977) | 3.40780315 |
28 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.36466198 |
29 | endothelial cell chemotaxis (GO:0035767) | 3.35802674 |
30 | cell proliferation involved in metanephros development (GO:0072203) | 3.35393744 |
31 | cell migration involved in heart development (GO:0060973) | 3.35122965 |
32 | keratan sulfate catabolic process (GO:0042340) | 3.34599646 |
33 | extracellular matrix assembly (GO:0085029) | 3.34212954 |
34 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 3.34008906 |
35 | lung vasculature development (GO:0060426) | 3.31577065 |
36 | mesenchymal-epithelial cell signaling (GO:0060638) | 3.29838946 |
37 | blood vessel endothelial cell migration (GO:0043534) | 3.28399280 |
38 | regulation of endothelial cell differentiation (GO:0045601) | 3.28196448 |
39 | extracellular fibril organization (GO:0043206) | 3.25507081 |
40 | cell differentiation involved in metanephros development (GO:0072202) | 3.24672364 |
41 | blood vessel maturation (GO:0001955) | 3.22306366 |
42 | endocrine hormone secretion (GO:0060986) | 3.22205641 |
43 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.20371975 |
44 | blood vessel remodeling (GO:0001974) | 3.19608963 |
45 | multicellular organismal macromolecule metabolic process (GO:0044259) | 3.19416492 |
46 | negative regulation of fatty acid transport (GO:2000192) | 3.18450060 |
47 | collagen metabolic process (GO:0032963) | 3.13487271 |
48 | ganglion development (GO:0061548) | 3.13344983 |
49 | collagen catabolic process (GO:0030574) | 3.12053894 |
50 | adhesion of symbiont to host cell (GO:0044650) | 3.09468964 |
51 | virion attachment to host cell (GO:0019062) | 3.09468964 |
52 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 3.08298634 |
53 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 3.08298634 |
54 | multicellular organismal catabolic process (GO:0044243) | 3.06808031 |
55 | fibroblast migration (GO:0010761) | 3.05885922 |
56 | wound healing, spreading of epidermal cells (GO:0035313) | 3.05551136 |
57 | endodermal cell differentiation (GO:0035987) | 3.05002589 |
58 | hippo signaling (GO:0035329) | 3.04356465 |
59 | artery development (GO:0060840) | 3.03775060 |
60 | multicellular organismal metabolic process (GO:0044236) | 3.01577134 |
61 | basement membrane organization (GO:0071711) | 3.01126264 |
62 | protein heterotrimerization (GO:0070208) | 3.01090390 |
63 | patterning of blood vessels (GO:0001569) | 2.98997054 |
64 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.98473318 |
65 | bone trabecula formation (GO:0060346) | 2.98197950 |
66 | protein localization to cell surface (GO:0034394) | 2.95524084 |
67 | protein localization to endosome (GO:0036010) | 2.94821627 |
68 | * substrate adhesion-dependent cell spreading (GO:0034446) | 2.94402872 |
69 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.91824973 |
70 | midgut development (GO:0007494) | 2.89971626 |
71 | muscle cell migration (GO:0014812) | 2.89836273 |
72 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 2.89088131 |
73 | artery morphogenesis (GO:0048844) | 2.87654168 |
74 | endothelial cell morphogenesis (GO:0001886) | 2.86560601 |
75 | endothelium development (GO:0003158) | 2.86466952 |
76 | metanephric epithelium development (GO:0072207) | 2.85288634 |
77 | stress fiber assembly (GO:0043149) | 2.84295580 |
78 | respiratory tube development (GO:0030323) | 2.83867099 |
79 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.83853943 |
80 | positive regulation of catenin import into nucleus (GO:0035413) | 2.82452148 |
81 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.79437785 |
82 | mesonephric tubule development (GO:0072164) | 2.78489894 |
83 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.78254842 |
84 | mesonephric epithelium development (GO:0072163) | 2.78063699 |
85 | pericardium development (GO:0060039) | 2.76110026 |
86 | extracellular matrix disassembly (GO:0022617) | 2.75449084 |
87 | substrate-dependent cell migration (GO:0006929) | 2.74919392 |
88 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.74305872 |
89 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.74200475 |
90 | cardiac myofibril assembly (GO:0055003) | 2.73393976 |
91 | positive regulation of vasculogenesis (GO:2001214) | 2.73066404 |
92 | fibril organization (GO:0097435) | 2.71946764 |
93 | chemical homeostasis within a tissue (GO:0048875) | 2.70074878 |
94 | chondrocyte development (GO:0002063) | 2.69707333 |
95 | * smooth muscle tissue development (GO:0048745) | 2.69334663 |
96 | positive regulation of mesenchymal cell proliferation (GO:0002053) | 2.68458943 |
97 | endocardial cushion morphogenesis (GO:0003203) | 2.67099312 |
98 | epithelial cell differentiation involved in kidney development (GO:0035850) | 2.66984247 |
99 | type B pancreatic cell proliferation (GO:0044342) | 2.66820708 |
100 | cell proliferation involved in kidney development (GO:0072111) | 2.66691305 |
101 | extracellular regulation of signal transduction (GO:1900115) | 2.66233176 |
102 | extracellular negative regulation of signal transduction (GO:1900116) | 2.66233176 |
103 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.66170233 |
104 | lung lobe morphogenesis (GO:0060463) | 2.66132133 |
105 | negative regulation of cell fate specification (GO:0009996) | 2.65120958 |
106 | cGMP-mediated signaling (GO:0019934) | 2.64845368 |
107 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.64214021 |
108 | aorta morphogenesis (GO:0035909) | 2.64049113 |
109 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.63831546 |
110 | adhesion of symbiont to host (GO:0044406) | 2.62808320 |
111 | facial nerve structural organization (GO:0021612) | 2.62690953 |
112 | venous blood vessel morphogenesis (GO:0048845) | 2.62496455 |
113 | endocardial cushion development (GO:0003197) | 2.62408091 |
114 | ureteric bud development (GO:0001657) | 2.61653025 |
115 | mesenchyme morphogenesis (GO:0072132) | 2.61427879 |
116 | apoptotic cell clearance (GO:0043277) | 2.61178033 |
117 | regulation of heart morphogenesis (GO:2000826) | 2.59871114 |
118 | polarized epithelial cell differentiation (GO:0030859) | 2.59376286 |
119 | outflow tract septum morphogenesis (GO:0003148) | 2.58696602 |
120 | pattern specification involved in kidney development (GO:0061004) | 2.57956328 |
121 | sprouting angiogenesis (GO:0002040) | 2.57316050 |
122 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 2.56946966 |
123 | blood vessel morphogenesis (GO:0048514) | 2.56712357 |
124 | * mesodermal cell differentiation (GO:0048333) | 2.56509759 |
125 | negative regulation of vascular permeability (GO:0043116) | 2.56057463 |
126 | epithelial cell-cell adhesion (GO:0090136) | 2.55944603 |
127 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.55832913 |
128 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.55607422 |
129 | camera-type eye morphogenesis (GO:0048593) | 2.55469602 |
130 | positive regulation of cell adhesion mediated by integrin (GO:0033630) | 2.55413442 |
131 | anterior/posterior axis specification, embryo (GO:0008595) | 2.53489901 |
132 | cellular response to epinephrine stimulus (GO:0071872) | 2.53321379 |
133 | relaxation of smooth muscle (GO:0044557) | 2.51611460 |
134 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.48687670 |
135 | low-density lipoprotein particle clearance (GO:0034383) | 2.45403888 |
136 | response to epinephrine (GO:0071871) | 2.42499419 |
137 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 2.41168993 |
138 | regulation of smooth muscle cell differentiation (GO:0051150) | 2.40702447 |
139 | regulation of cardiac muscle cell differentiation (GO:2000725) | 2.40364003 |
140 | vasculature development (GO:0001944) | 2.40124678 |
141 | mesenchymal cell differentiation (GO:0048762) | 2.39114952 |
142 | regulation of vasculogenesis (GO:2001212) | 2.37336086 |
143 | tonic smooth muscle contraction (GO:0014820) | 2.36290091 |
144 | smooth muscle cell differentiation (GO:0051145) | 2.35553945 |
145 | * extracellular matrix organization (GO:0030198) | 2.33274663 |
146 | skin morphogenesis (GO:0043589) | 2.33161847 |
147 | * extracellular structure organization (GO:0043062) | 2.32443812 |
148 | myofibril assembly (GO:0030239) | 2.30031042 |
149 | adrenal gland development (GO:0030325) | 2.27729600 |
150 | lung alveolus development (GO:0048286) | 2.27376980 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.62477804 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.88779191 |
3 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.69768063 |
4 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.46585704 |
5 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.46205647 |
6 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.44487743 |
7 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.43887515 |
8 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.39544647 |
9 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.26945096 |
10 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.20230793 |
11 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.11603689 |
12 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.09918203 |
13 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.09271711 |
14 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.09271711 |
15 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.06226442 |
16 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.05619162 |
17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.01516433 |
18 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.97307690 |
19 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.94379808 |
20 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.92837972 |
21 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.88920140 |
22 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.88241746 |
23 | CJUN_26792858_Chip-Seq_BT549_Human | 1.86240062 |
24 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.84066398 |
25 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.78580340 |
26 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.78452491 |
27 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.77314796 |
28 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.73454706 |
29 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.69042212 |
30 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.66861226 |
31 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.66560734 |
32 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.66351767 |
33 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.63790470 |
34 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.61396743 |
35 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.61083689 |
36 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.60089681 |
37 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.59792669 |
38 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.58745173 |
39 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.58510187 |
40 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.56966123 |
41 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.54498169 |
42 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.54132150 |
43 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.50776589 |
44 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.50143368 |
45 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.49994554 |
46 | * NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.48691211 |
47 | * NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.48691211 |
48 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.47753402 |
49 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.46613854 |
50 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.44485526 |
51 | TP53_16413492_ChIP-PET_HCT116_Human | 1.42849545 |
52 | * ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.36205224 |
53 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.35420088 |
54 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.35149789 |
55 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.34820229 |
56 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.34094314 |
57 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.34087863 |
58 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.32519956 |
59 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.32427128 |
60 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.31294099 |
61 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.30955585 |
62 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.30940215 |
63 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.30929875 |
64 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.30305417 |
65 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.29391883 |
66 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.28029029 |
67 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.25582686 |
68 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.24704310 |
69 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.23805693 |
70 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.22823576 |
71 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.22232122 |
72 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.20889692 |
73 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 1.20454695 |
74 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.17686666 |
75 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.16767377 |
76 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.16719389 |
77 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.16145268 |
78 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.15502236 |
79 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.14717743 |
80 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.14646521 |
81 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.12552045 |
82 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.11694528 |
83 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.10428294 |
84 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.10428294 |
85 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.10219517 |
86 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.06863687 |
87 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.06731116 |
88 | * EZH2_22144423_ChIP-Seq_EOC_Human | 1.05783519 |
89 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.05088790 |
90 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.04592918 |
91 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.04169076 |
92 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.04034509 |
93 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.03353332 |
94 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.03353332 |
95 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.01961798 |
96 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.01784581 |
97 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.00465222 |
98 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.00111682 |
99 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.99635829 |
100 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.99374621 |
101 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.99011240 |
102 | RXR_22108803_ChIP-Seq_LS180_Human | 0.98548055 |
103 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.97806512 |
104 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.97016498 |
105 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.96960990 |
106 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.96834050 |
107 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.96752469 |
108 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.96560349 |
109 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.96335154 |
110 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.94857610 |
111 | AR_25329375_ChIP-Seq_VCAP_Human | 0.94804855 |
112 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.94519062 |
113 | STAT3_23295773_ChIP-Seq_U87_Human | 0.94062717 |
114 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.93881470 |
115 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.93691787 |
116 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.93465629 |
117 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.93325479 |
118 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.93300266 |
119 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.91745882 |
120 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91108672 |
121 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.91020343 |
122 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90599050 |
123 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.90490078 |
124 | * KDM2B_26808549_Chip-Seq_REH_Human | 0.89647057 |
125 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.89565567 |
126 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.89546843 |
127 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.88828965 |
128 | P300_19829295_ChIP-Seq_ESCs_Human | 0.88753238 |
129 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.88486717 |
130 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.88196799 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 5.36271463 |
2 | MP0004272_abnormal_basement_membrane | 4.36867214 |
3 | MP0010368_abnormal_lymphatic_system | 4.21326654 |
4 | MP0005275_abnormal_skin_tensile | 3.88747478 |
5 | MP0001958_emphysema | 3.57126583 |
6 | MP0005503_abnormal_tendon_morphology | 3.21094581 |
7 | MP0003705_abnormal_hypodermis_morpholog | 3.06032846 |
8 | MP0005623_abnormal_meninges_morphology | 3.03764966 |
9 | MP0001879_abnormal_lymphatic_vessel | 2.99966248 |
10 | MP0003279_aneurysm | 2.88164352 |
11 | MP0009384_cardiac_valve_regurgitation | 2.55429900 |
12 | * MP0000534_abnormal_ureter_morphology | 2.19764108 |
13 | MP0003566_abnormal_cell_adhesion | 2.18352013 |
14 | MP0000751_myopathy | 2.17034786 |
15 | MP0003950_abnormal_plasma_membrane | 2.16389033 |
16 | MP0000537_abnormal_urethra_morphology | 2.14315865 |
17 | MP0000767_abnormal_smooth_muscle | 2.13099665 |
18 | * MP0003942_abnormal_urinary_system | 2.13013609 |
19 | MP0005670_abnormal_white_adipose | 2.10192856 |
20 | MP0002295_abnormal_pulmonary_circulatio | 2.05696155 |
21 | MP0001542_abnormal_bone_strength | 1.96980755 |
22 | MP0003385_abnormal_body_wall | 1.84517267 |
23 | MP0003091_abnormal_cell_migration | 1.67387850 |
24 | MP0003115_abnormal_respiratory_system | 1.62103623 |
25 | MP0010030_abnormal_orbit_morphology | 1.59664796 |
26 | MP0002282_abnormal_trachea_morphology | 1.58884070 |
27 | MP0005508_abnormal_skeleton_morphology | 1.58297814 |
28 | MP0003941_abnormal_skin_development | 1.57969985 |
29 | MP0009250_abnormal_appendicular_skeleto | 1.56857044 |
30 | MP0004084_abnormal_cardiac_muscle | 1.55590112 |
31 | MP0005257_abnormal_intraocular_pressure | 1.55483350 |
32 | MP0009053_abnormal_anal_canal | 1.54926709 |
33 | MP0000516_abnormal_urinary_system | 1.47927196 |
34 | MP0005367_renal/urinary_system_phenotyp | 1.47927196 |
35 | MP0004130_abnormal_muscle_cell | 1.42377156 |
36 | MP0001661_extended_life_span | 1.41419930 |
37 | MP0006138_congestive_heart_failure | 1.41100980 |
38 | MP0005595_abnormal_vascular_smooth | 1.37949358 |
39 | MP0009780_abnormal_chondrocyte_physiolo | 1.36033625 |
40 | MP0002249_abnormal_larynx_morphology | 1.32876276 |
41 | MP0002128_abnormal_blood_circulation | 1.32782275 |
42 | MP0003045_fibrosis | 1.32422454 |
43 | MP0000013_abnormal_adipose_tissue | 1.31620658 |
44 | MP0005023_abnormal_wound_healing | 1.26768108 |
45 | MP0001614_abnormal_blood_vessel | 1.26638033 |
46 | MP0003935_abnormal_craniofacial_develop | 1.25310831 |
47 | MP0006054_spinal_hemorrhage | 1.25159892 |
48 | MP0002925_abnormal_cardiovascular_devel | 1.20417466 |
49 | MP0002932_abnormal_joint_morphology | 1.19770458 |
50 | MP0010234_abnormal_vibrissa_follicle | 1.19213309 |
51 | MP0001986_abnormal_taste_sensitivity | 1.18084371 |
52 | MP0000538_abnormal_urinary_bladder | 1.16652921 |
53 | MP0002168_other_aberrant_phenotype | 1.16208902 |
54 | MP0002133_abnormal_respiratory_system | 1.14867271 |
55 | MP0005388_respiratory_system_phenotype | 1.14867271 |
56 | MP0000163_abnormal_cartilage_morphology | 1.12284573 |
57 | MP0002108_abnormal_muscle_morphology | 1.11969538 |
58 | MP0002896_abnormal_bone_mineralization | 1.11602683 |
59 | MP0003122_maternal_imprinting | 1.09736905 |
60 | MP0002115_abnormal_skeleton_extremities | 1.07271693 |
61 | MP0000462_abnormal_digestive_system | 1.06979355 |
62 | MP0001175_abnormal_lung_morphology | 1.04536307 |
63 | MP0005167_abnormal_blood-brain_barrier | 1.02934790 |
64 | MP0003937_abnormal_limbs/digits/tail_de | 1.02813187 |
65 | MP0002233_abnormal_nose_morphology | 1.02220728 |
66 | MP0002060_abnormal_skin_morphology | 1.01281646 |
67 | MP0001664_abnormal_digestion | 1.00573230 |
68 | MP0000733_abnormal_muscle_development | 1.00560156 |
69 | * MP0002135_abnormal_kidney_morphology | 1.00067876 |
70 | MP0001270_distended_abdomen | 0.99860109 |
71 | MP0000762_abnormal_tongue_morphology | 0.98512191 |
72 | MP0000230_abnormal_systemic_arterial | 0.98096953 |
73 | MP0004782_abnormal_surfactant_physiolog | 0.98092324 |
74 | MP0004883_abnormal_blood_vessel | 0.96862245 |
75 | MP0003252_abnormal_bile_duct | 0.94983204 |
76 | MP0010352_gastrointestinal_tract_polyps | 0.94221136 |
77 | MP0005164_abnormal_response_to | 0.93257815 |
78 | MP0003283_abnormal_digestive_organ | 0.93179831 |
79 | MP0002127_abnormal_cardiovascular_syste | 0.93121545 |
80 | MP0004134_abnormal_chest_morphology | 0.93026422 |
81 | MP0002971_abnormal_brown_adipose | 0.90757072 |
82 | MP0008004_abnormal_stomach_pH | 0.90059164 |
83 | MP0000428_abnormal_craniofacial_morphol | 0.89519668 |
84 | MP0001177_atelectasis | 0.89346507 |
85 | MP0003828_pulmonary_edema | 0.89343364 |
86 | MP0002113_abnormal_skeleton_development | 0.89086122 |
87 | MP0005197_abnormal_uvea_morphology | 0.88910521 |
88 | MP0003755_abnormal_palate_morphology | 0.88883428 |
89 | MP0001299_abnormal_eye_distance/ | 0.88766700 |
90 | MP0000003_abnormal_adipose_tissue | 0.87706702 |
91 | MP0005375_adipose_tissue_phenotype | 0.86553378 |
92 | MP0005385_cardiovascular_system_phenoty | 0.85982087 |
93 | MP0001544_abnormal_cardiovascular_syste | 0.85982087 |
94 | MP0002109_abnormal_limb_morphology | 0.84521661 |
95 | MP0002254_reproductive_system_inflammat | 0.84261143 |
96 | MP0010386_abnormal_urinary_bladder | 0.82930232 |
97 | MP0004484_altered_response_of | 0.82334453 |
98 | MP0004036_abnormal_muscle_relaxation | 0.81994258 |
99 | MP0005248_abnormal_Harderian_gland | 0.81902371 |
100 | MP0000266_abnormal_heart_morphology | 0.81840125 |
101 | MP0000049_abnormal_middle_ear | 0.80765472 |
102 | MP0001756_abnormal_urination | 0.79974863 |
103 | MP0000432_abnormal_head_morphology | 0.79288170 |
104 | MP0001915_intracranial_hemorrhage | 0.78973663 |
105 | MP0004085_abnormal_heartbeat | 0.78177580 |
106 | MP0010630_abnormal_cardiac_muscle | 0.77219904 |
107 | MP0003300_gastrointestinal_ulcer | 0.76837748 |
108 | MP0008775_abnormal_heart_ventricle | 0.76584281 |
109 | MP0003123_paternal_imprinting | 0.73254716 |
110 | MP0000759_abnormal_skeletal_muscle | 0.72304908 |
111 | MP0000566_synostosis | 0.71079046 |
112 | MP0002116_abnormal_craniofacial_bone | 0.70862223 |
113 | MP0005171_absent_coat_pigmentation | 0.70220637 |
114 | MP0005193_abnormal_anterior_eye | 0.69621177 |
115 | MP0005390_skeleton_phenotype | 0.69588803 |
116 | MP0004043_abnormal_pH_regulation | 0.69316195 |
117 | MP0001849_ear_inflammation | 0.68200192 |
118 | MP0002933_joint_inflammation | 0.68079786 |
119 | MP0001784_abnormal_fluid_regulation | 0.67967297 |
120 | MP0003011_delayed_dark_adaptation | 0.67797474 |
121 | MP0005620_abnormal_muscle_contractility | 0.67433295 |
122 | MP0002136_abnormal_kidney_physiology | 0.67051539 |
123 | MP0005666_abnormal_adipose_tissue | 0.66706349 |
124 | MP0000749_muscle_degeneration | 0.65922350 |
125 | MP0001243_abnormal_dermal_layer | 0.64946684 |
126 | MP0005369_muscle_phenotype | 0.64099828 |
127 | MP0000750_abnormal_muscle_regeneration | 0.63946903 |
128 | MP0005165_increased_susceptibility_to | 0.61997812 |
129 | MP0004215_abnormal_myocardial_fiber | 0.61461669 |
130 | MP0002972_abnormal_cardiac_muscle | 0.60905159 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Aortic aneurysm (HP:0004942) | 5.26016669 |
2 | Aortic dissection (HP:0002647) | 4.73647840 |
3 | Protrusio acetabuli (HP:0003179) | 4.70183067 |
4 | Broad metatarsal (HP:0001783) | 4.56013420 |
5 | Premature rupture of membranes (HP:0001788) | 4.35183950 |
6 | Type 1 muscle fiber predominance (HP:0003803) | 4.06243650 |
7 | Shallow orbits (HP:0000586) | 4.00997466 |
8 | Cerebral aneurysm (HP:0004944) | 3.92310885 |
9 | Vascular tortuosity (HP:0004948) | 3.91581979 |
10 | Focal segmental glomerulosclerosis (HP:0000097) | 3.88587195 |
11 | Ankle contracture (HP:0006466) | 3.80914245 |
12 | Mesangial abnormality (HP:0001966) | 3.65254117 |
13 | Hematochezia (HP:0002573) | 3.47992516 |
14 | Arterial tortuosity (HP:0005116) | 3.32098780 |
15 | Follicular hyperkeratosis (HP:0007502) | 3.25212399 |
16 | Bladder diverticulum (HP:0000015) | 3.20629136 |
17 | Mitral valve prolapse (HP:0001634) | 3.18320984 |
18 | Atrophic scars (HP:0001075) | 3.08777888 |
19 | Aneurysm (HP:0002617) | 3.08569364 |
20 | Glomerulosclerosis (HP:0000096) | 3.04406762 |
21 | Camptodactyly of toe (HP:0001836) | 2.93189399 |
22 | Dilatation of the ascending aorta (HP:0005111) | 2.90999040 |
23 | Lymphangioma (HP:0100764) | 2.86282815 |
24 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.82131438 |
25 | Short 4th metacarpal (HP:0010044) | 2.82131438 |
26 | Slender build (HP:0001533) | 2.71174254 |
27 | Nephritis (HP:0000123) | 2.69893293 |
28 | Increased density of long bones (HP:0006392) | 2.62728682 |
29 | Soft skin (HP:0000977) | 2.61803361 |
30 | Pulmonary artery stenosis (HP:0004415) | 2.59177519 |
31 | Polycythemia (HP:0001901) | 2.58887112 |
32 | Increased variability in muscle fiber diameter (HP:0003557) | 2.56280197 |
33 | Neoplasm of the heart (HP:0100544) | 2.53354495 |
34 | Broad ribs (HP:0000885) | 2.50756279 |
35 | Overgrowth (HP:0001548) | 2.48863606 |
36 | Deep venous thrombosis (HP:0002625) | 2.47908228 |
37 | Venous insufficiency (HP:0005293) | 2.47840352 |
38 | Long toe (HP:0010511) | 2.47487884 |
39 | Wormian bones (HP:0002645) | 2.44694350 |
40 | Knee flexion contracture (HP:0006380) | 2.41055855 |
41 | Abnormality of the 4th metacarpal (HP:0010012) | 2.39351803 |
42 | Hydroureter (HP:0000072) | 2.37233662 |
43 | Peritonitis (HP:0002586) | 2.36489412 |
44 | Papilledema (HP:0001085) | 2.35675087 |
45 | Hypoventilation (HP:0002791) | 2.35394663 |
46 | Increased corneal curvature (HP:0100692) | 2.33424476 |
47 | Keratoconus (HP:0000563) | 2.33424476 |
48 | Renal duplication (HP:0000075) | 2.33190203 |
49 | Decreased circulating renin level (HP:0003351) | 2.31771636 |
50 | Round ear (HP:0100830) | 2.29651008 |
51 | Hypoplasia of the iris (HP:0007676) | 2.28554215 |
52 | Bowel diverticulosis (HP:0005222) | 2.27369978 |
53 | Ectopia lentis (HP:0001083) | 2.26686167 |
54 | Abnormal albumin level (HP:0012116) | 2.23905187 |
55 | Hypoalbuminemia (HP:0003073) | 2.23905187 |
56 | Bicuspid aortic valve (HP:0001647) | 2.23592514 |
57 | Tubulointerstitial fibrosis (HP:0005576) | 2.20519051 |
58 | Buphthalmos (HP:0000557) | 2.18076725 |
59 | Chondrocalcinosis (HP:0000934) | 2.17916866 |
60 | Hepatoblastoma (HP:0002884) | 2.16739669 |
61 | Venous abnormality (HP:0002624) | 2.15623391 |
62 | Disproportionate tall stature (HP:0001519) | 2.15433860 |
63 | Mitral regurgitation (HP:0001653) | 2.14964398 |
64 | Bell-shaped thorax (HP:0001591) | 2.14135236 |
65 | Infantile muscular hypotonia (HP:0008947) | 2.13867538 |
66 | Joint contractures involving the joints of the feet (HP:0100492) | 2.13841831 |
67 | Flexion contracture of toe (HP:0005830) | 2.13841831 |
68 | Hypoplastic ischia (HP:0003175) | 2.13833635 |
69 | Coronal craniosynostosis (HP:0004440) | 2.12724205 |
70 | Hip contracture (HP:0003273) | 2.12673534 |
71 | Spontaneous hematomas (HP:0007420) | 2.12530912 |
72 | Blue sclerae (HP:0000592) | 2.10940749 |
73 | Midline defect of the nose (HP:0004122) | 2.10291261 |
74 | Stage 5 chronic kidney disease (HP:0003774) | 2.09322154 |
75 | Wrist flexion contracture (HP:0001239) | 2.08892699 |
76 | Mesomelia (HP:0003027) | 2.06504746 |
77 | Vitreoretinal degeneration (HP:0000655) | 2.05946149 |
78 | Visceral angiomatosis (HP:0100761) | 2.05557672 |
79 | Fragile skin (HP:0001030) | 2.05517375 |
80 | Wide anterior fontanel (HP:0000260) | 2.05172426 |
81 | Abnormality of dentin (HP:0010299) | 2.04999703 |
82 | Hyperextensible skin (HP:0000974) | 2.04516916 |
83 | Ulnar bowing (HP:0003031) | 2.04197073 |
84 | Distal arthrogryposis (HP:0005684) | 2.03573177 |
85 | Short hallux (HP:0010109) | 2.03269922 |
86 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.02495294 |
87 | Abnormality of Sharpey fibers (HP:0100685) | 2.01920703 |
88 | Aortic regurgitation (HP:0001659) | 2.01680057 |
89 | Neonatal short-limb short stature (HP:0008921) | 1.97237578 |
90 | Vertebral compression fractures (HP:0002953) | 1.96870626 |
91 | Morphological abnormality of the middle ear (HP:0008609) | 1.96569580 |
92 | Increased connective tissue (HP:0009025) | 1.96311090 |
93 | Mild short stature (HP:0003502) | 1.96184129 |
94 | Spondylolisthesis (HP:0003302) | 1.95588129 |
95 | Limited hip movement (HP:0008800) | 1.94935029 |
96 | Abnormality of the ischium (HP:0003174) | 1.94875323 |
97 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.94477572 |
98 | Hyperactive renin-angiotensin system (HP:0000841) | 1.94103425 |
99 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.93206168 |
100 | Hemangiomatosis (HP:0007461) | 1.92327636 |
101 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.91771366 |
102 | Osteolytic defects of the hand bones (HP:0009699) | 1.91771366 |
103 | Cervical subluxation (HP:0003308) | 1.90600518 |
104 | Aortic valve stenosis (HP:0001650) | 1.90092348 |
105 | Abnormality of the anterior chamber (HP:0000593) | 1.89486491 |
106 | Glomerulonephritis (HP:0000099) | 1.88446903 |
107 | Shawl scrotum (HP:0000049) | 1.86018031 |
108 | Rectal prolapse (HP:0002035) | 1.85681586 |
109 | Striae distensae (HP:0001065) | 1.85652752 |
110 | Biconcave vertebral bodies (HP:0004586) | 1.85304765 |
111 | Joint laxity (HP:0001388) | 1.83834636 |
112 | Broad toe (HP:0001837) | 1.83150575 |
113 | Elbow flexion contracture (HP:0002987) | 1.82338661 |
114 | Malnutrition (HP:0004395) | 1.81633268 |
115 | Spinal rigidity (HP:0003306) | 1.80755777 |
116 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.79889496 |
117 | Abnormality of the peritoneum (HP:0002585) | 1.79881111 |
118 | Turricephaly (HP:0000262) | 1.78559612 |
119 | Cardiovascular calcification (HP:0011915) | 1.77949326 |
120 | Esophageal varix (HP:0002040) | 1.77818114 |
121 | Persistence of primary teeth (HP:0006335) | 1.77153261 |
122 | Osteoarthritis (HP:0002758) | 1.76332152 |
123 | Interstitial pulmonary disease (HP:0006530) | 1.75985778 |
124 | Genu recurvatum (HP:0002816) | 1.73168902 |
125 | Mitral stenosis (HP:0001718) | 1.71640473 |
126 | Abnormality of the acetabulum (HP:0003170) | 1.70008964 |
127 | Joint stiffness (HP:0001387) | 1.69139916 |
128 | Arachnodactyly (HP:0001166) | 1.67877958 |
129 | Ovoid vertebral bodies (HP:0003300) | 1.66754522 |
130 | Pulmonary hypertension (HP:0002092) | 1.64992841 |
131 | Short clavicles (HP:0000894) | 1.64402822 |
132 | Redundant skin (HP:0001582) | 1.64088503 |
133 | Protruding ear (HP:0000411) | 1.61564332 |
134 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.60750902 |
135 | Narrow nasal bridge (HP:0000446) | 1.59625725 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TIE1 | 4.41130730 |
2 | DDR2 | 3.99379315 |
3 | TGFBR2 | 3.70979288 |
4 | TTN | 3.68236575 |
5 | LATS1 | 3.45562485 |
6 | EPHB2 | 3.36293203 |
7 | PDGFRA | 3.31806751 |
8 | MYLK | 3.02933692 |
9 | EPHA3 | 2.95856564 |
10 | PIK3CG | 2.92112143 |
11 | WNK4 | 2.54686583 |
12 | TRIB3 | 2.16585822 |
13 | DMPK | 2.03821852 |
14 | GRK7 | 1.95705520 |
15 | RIPK1 | 1.94567527 |
16 | STK39 | 1.86654746 |
17 | FER | 1.84985891 |
18 | SIK1 | 1.80387061 |
19 | TGFBR1 | 1.74962544 |
20 | PAK4 | 1.68138186 |
21 | KDR | 1.66933370 |
22 | LATS2 | 1.63483502 |
23 | CAMK1G | 1.63013128 |
24 | PAK2 | 1.61136892 |
25 | NTRK1 | 1.52600525 |
26 | CAMK1D | 1.43052616 |
27 | PDGFRB | 1.41699002 |
28 | PTK2B | 1.39750269 |
29 | LIMK1 | 1.37191194 |
30 | NLK | 1.37121759 |
31 | PKN2 | 1.35617219 |
32 | ERN1 | 1.34826346 |
33 | PAK3 | 1.32733965 |
34 | PTK2 | 1.30119909 |
35 | FGFR4 | 1.27578211 |
36 | PTK6 | 1.27233237 |
37 | FGFR2 | 1.26701486 |
38 | OXSR1 | 1.25738597 |
39 | EPHB1 | 1.20909569 |
40 | TESK1 | 1.14278897 |
41 | FLT3 | 1.12348396 |
42 | LRRK2 | 1.07893412 |
43 | TRPM7 | 1.07256484 |
44 | NUAK1 | 1.02667149 |
45 | OBSCN | 0.98048090 |
46 | PIK3CA | 0.97893174 |
47 | PRKCH | 0.97700765 |
48 | MET | 0.93375957 |
49 | FRK | 0.92596792 |
50 | ROCK1 | 0.91339325 |
51 | FGFR3 | 0.90558533 |
52 | STK38L | 0.90005240 |
53 | MAPK7 | 0.87528018 |
54 | KIT | 0.87397048 |
55 | STK3 | 0.87230483 |
56 | WNK1 | 0.87065930 |
57 | CAMK1 | 0.85614896 |
58 | FGFR1 | 0.85524276 |
59 | BMX | 0.81744319 |
60 | MAPKAPK3 | 0.80570828 |
61 | AKT3 | 0.80507917 |
62 | ACVR1B | 0.79927854 |
63 | RET | 0.75982792 |
64 | GRK1 | 0.75206644 |
65 | MAP3K7 | 0.74866873 |
66 | MELK | 0.72766401 |
67 | EEF2K | 0.72518667 |
68 | NEK9 | 0.64431683 |
69 | MTOR | 0.64362419 |
70 | DAPK3 | 0.64302728 |
71 | MAPK12 | 0.63795673 |
72 | PRKD1 | 0.60559589 |
73 | GSK3A | 0.60525699 |
74 | PRKAA1 | 0.59757921 |
75 | MATK | 0.56667463 |
76 | ERBB2 | 0.56158742 |
77 | ERBB4 | 0.55256125 |
78 | PRKD2 | 0.54678954 |
79 | PRKD3 | 0.54467138 |
80 | MAP3K6 | 0.54276863 |
81 | MAPK4 | 0.53513782 |
82 | KSR2 | 0.53241067 |
83 | MAP2K1 | 0.52857342 |
84 | ERBB3 | 0.51316170 |
85 | JAK1 | 0.49303371 |
86 | SGK494 | 0.48974187 |
87 | SGK223 | 0.48974187 |
88 | PRKCE | 0.48159127 |
89 | SRC | 0.47295974 |
90 | ADRBK2 | 0.45517253 |
91 | INSR | 0.44537792 |
92 | ILK | 0.43221483 |
93 | ROCK2 | 0.42571333 |
94 | MAP2K2 | 0.42294361 |
95 | IGF1R | 0.42217768 |
96 | EPHA2 | 0.41203127 |
97 | CAMK2B | 0.40842657 |
98 | ABL2 | 0.40465134 |
99 | SGK3 | 0.39851644 |
100 | PINK1 | 0.39601038 |
101 | CDK6 | 0.38102800 |
102 | MARK2 | 0.36490008 |
103 | PRKG1 | 0.36035460 |
104 | CDC42BPA | 0.33807549 |
105 | MAP3K2 | 0.32865652 |
106 | ABL1 | 0.31983561 |
107 | PLK2 | 0.31899643 |
108 | ZAP70 | 0.31726974 |
109 | GRK5 | 0.30474350 |
110 | MAPK1 | 0.29771970 |
111 | LMTK2 | 0.29626226 |
112 | NTRK3 | 0.29556539 |
113 | STK24 | 0.28803647 |
114 | EGFR | 0.28587699 |
115 | RPS6KA2 | 0.28443896 |
116 | FYN | 0.28381975 |
117 | RPS6KA6 | 0.27439422 |
118 | DYRK1B | 0.27029850 |
119 | STK38 | 0.26302436 |
120 | PDPK1 | 0.25317872 |
121 | STK10 | 0.25277437 |
122 | KSR1 | 0.24852595 |
123 | PRKAA2 | 0.24187039 |
124 | TAOK1 | 0.23790767 |
125 | ADRBK1 | 0.23378985 |
126 | PDK2 | 0.23235633 |
127 | SGK2 | 0.22508884 |
128 | DAPK2 | 0.22179517 |
129 | CAMK4 | 0.21636978 |
130 | EPHA4 | 0.18190127 |
131 | PRKG2 | 0.17516477 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * ECM-receptor interaction_Homo sapiens_hsa04512 | 3.96263974 |
2 | * Focal adhesion_Homo sapiens_hsa04510 | 2.95850514 |
3 | Protein digestion and absorption_Homo sapiens_hsa04974 | 2.44322472 |
4 | Adherens junction_Homo sapiens_hsa04520 | 2.33497927 |
5 | Amoebiasis_Homo sapiens_hsa05146 | 2.26518615 |
6 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 2.09672650 |
7 | Small cell lung cancer_Homo sapiens_hsa05222 | 2.08764024 |
8 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.92151920 |
9 | * Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.91963503 |
10 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.81446259 |
11 | Axon guidance_Homo sapiens_hsa04360 | 1.79896118 |
12 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.74949896 |
13 | * Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.74240561 |
14 | * Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.68364703 |
15 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.67990830 |
16 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.55274517 |
17 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.47502106 |
18 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.37834545 |
19 | Bladder cancer_Homo sapiens_hsa05219 | 1.37680644 |
20 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.36778905 |
21 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.36404965 |
22 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.34148694 |
23 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.30683882 |
24 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.29247118 |
25 | * PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.29012852 |
26 | * Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.28984856 |
27 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.28401819 |
28 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.27397029 |
29 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.26630115 |
30 | Tight junction_Homo sapiens_hsa04530 | 1.21354755 |
31 | Renin secretion_Homo sapiens_hsa04924 | 1.20054624 |
32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.17999444 |
33 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.15045472 |
34 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.15021820 |
35 | Platelet activation_Homo sapiens_hsa04611 | 1.14177821 |
36 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.12865377 |
37 | Pathways in cancer_Homo sapiens_hsa05200 | 1.12156481 |
38 | Melanoma_Homo sapiens_hsa05218 | 1.07945022 |
39 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.03899607 |
40 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.02743062 |
41 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.02474462 |
42 | Prostate cancer_Homo sapiens_hsa05215 | 0.99977712 |
43 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.99395734 |
44 | Glioma_Homo sapiens_hsa05214 | 0.99352893 |
45 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.99115912 |
46 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.98120555 |
47 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.98106277 |
48 | Lysine degradation_Homo sapiens_hsa00310 | 0.94827515 |
49 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.94807978 |
50 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.94738113 |
51 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.93641916 |
52 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.93618285 |
53 | Melanogenesis_Homo sapiens_hsa04916 | 0.93364387 |
54 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.92599181 |
55 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.91378099 |
56 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.90873806 |
57 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.89769470 |
58 | Gap junction_Homo sapiens_hsa04540 | 0.89453827 |
59 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.87505757 |
60 | Viral myocarditis_Homo sapiens_hsa05416 | 0.85930929 |
61 | Endometrial cancer_Homo sapiens_hsa05213 | 0.83570328 |
62 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.82652074 |
63 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.80897631 |
64 | Histidine metabolism_Homo sapiens_hsa00340 | 0.79876224 |
65 | Malaria_Homo sapiens_hsa05144 | 0.79323060 |
66 | ABC transporters_Homo sapiens_hsa02010 | 0.77118354 |
67 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.74484791 |
68 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.72829814 |
69 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.72264246 |
70 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.72115186 |
71 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.71991847 |
72 | Colorectal cancer_Homo sapiens_hsa05210 | 0.71156670 |
73 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.70735358 |
74 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.70348879 |
75 | Cocaine addiction_Homo sapiens_hsa05030 | 0.69894957 |
76 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.69480168 |
77 | Bile secretion_Homo sapiens_hsa04976 | 0.69435051 |
78 | Insulin resistance_Homo sapiens_hsa04931 | 0.69412666 |
79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.69186450 |
80 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.68907103 |
81 | Salivary secretion_Homo sapiens_hsa04970 | 0.68241543 |
82 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.67783025 |
83 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.66598744 |
84 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.64756778 |
85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.64410057 |
86 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.64015846 |
87 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.63651016 |
88 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.62862996 |
89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.62610573 |
90 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.60800385 |
91 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.60447088 |
92 | Insulin secretion_Homo sapiens_hsa04911 | 0.60288579 |
93 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.59875756 |
94 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.58996561 |
95 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.58333688 |
96 | Mineral absorption_Homo sapiens_hsa04978 | 0.57325335 |
97 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.57246787 |
98 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.54227959 |
99 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.54171739 |
100 | * Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52295770 |
101 | Pertussis_Homo sapiens_hsa05133 | 0.51697914 |
102 | Circadian rhythm_Homo sapiens_hsa04710 | 0.51348323 |
103 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.50977067 |
104 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.50466255 |
105 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.50411931 |
106 | Endocytosis_Homo sapiens_hsa04144 | 0.50134071 |
107 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.49764723 |
108 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.49566386 |
109 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.49214652 |
110 | HTLV-I infection_Homo sapiens_hsa05166 | 0.49111800 |
111 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.49080550 |
112 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48886182 |
113 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.48866983 |
114 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.46829638 |
115 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.46430548 |
116 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.46042732 |
117 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.42723606 |
118 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.42639112 |
119 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.42075405 |
120 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.41895311 |
121 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.41498319 |
122 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.41364923 |
123 | Prion diseases_Homo sapiens_hsa05020 | 0.41303174 |
124 | Salmonella infection_Homo sapiens_hsa05132 | 0.40747470 |
125 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.40355751 |
126 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.39966211 |
127 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.39733974 |
128 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.39431854 |
129 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.39333089 |
130 | Circadian entrainment_Homo sapiens_hsa04713 | 0.39260807 |
131 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.38189546 |
132 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.38111254 |
133 | Phagosome_Homo sapiens_hsa04145 | 0.37972320 |