Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of respiratory burst (GO:0060267) | 8.67957699 |
2 | angiotensin maturation (GO:0002003) | 8.26682684 |
3 | disruption of cells of other organism (GO:0044364) | 8.11710003 |
4 | killing of cells of other organism (GO:0031640) | 8.11710003 |
5 | defense response to fungus (GO:0050832) | 8.05588304 |
6 | antibacterial humoral response (GO:0019731) | 7.53195157 |
7 | antimicrobial humoral response (GO:0019730) | 7.32529589 |
8 | glomerular filtration (GO:0003094) | 7.13035550 |
9 | renal filtration (GO:0097205) | 6.49431375 |
10 | regulation of bile acid biosynthetic process (GO:0070857) | 6.49076477 |
11 | regulation of guanylate cyclase activity (GO:0031282) | 6.15510033 |
12 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 5.81450625 |
13 | vitamin A metabolic process (GO:0006776) | 5.79083042 |
14 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 5.74971305 |
15 | regulation of respiratory burst (GO:0060263) | 5.73318563 |
16 | digestive system process (GO:0022600) | 5.59278791 |
17 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 5.58215752 |
18 | actin filament depolymerization (GO:0030042) | 5.57785384 |
19 | intestinal epithelial cell development (GO:0060576) | 5.44556641 |
20 | flavonoid metabolic process (GO:0009812) | 5.38990071 |
21 | positive regulation of pseudopodium assembly (GO:0031274) | 5.30131499 |
22 | adhesion of symbiont to host cell (GO:0044650) | 4.92705040 |
23 | virion attachment to host cell (GO:0019062) | 4.92705040 |
24 | endocrine process (GO:0050886) | 4.91353386 |
25 | regulation of systemic arterial blood pressure by hormone (GO:0001990) | 4.91353386 |
26 | regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) | 4.91353386 |
27 | innate immune response in mucosa (GO:0002227) | 4.87975892 |
28 | oligosaccharide biosynthetic process (GO:0009312) | 4.86258932 |
29 | glucose 6-phosphate metabolic process (GO:0051156) | 4.78365486 |
30 | regulation of pseudopodium assembly (GO:0031272) | 4.75729559 |
31 | drug catabolic process (GO:0042737) | 4.66201184 |
32 | transepithelial transport (GO:0070633) | 4.59241656 |
33 | positive regulation of guanylate cyclase activity (GO:0031284) | 4.51609676 |
34 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 4.46307470 |
35 | response to fungus (GO:0009620) | 4.41953928 |
36 | regulation of vitamin metabolic process (GO:0030656) | 4.31534853 |
37 | regulation of systemic arterial blood pressure (GO:0003073) | 4.29682633 |
38 | renal system process involved in regulation of blood volume (GO:0001977) | 4.22291189 |
39 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 4.18584325 |
40 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 4.18584325 |
41 | urea cycle (GO:0000050) | 4.17573546 |
42 | urea metabolic process (GO:0019627) | 4.17573546 |
43 | lipoprotein metabolic process (GO:0042157) | 4.15553221 |
44 | NADH metabolic process (GO:0006734) | 4.13610378 |
45 | mucosal immune response (GO:0002385) | 4.08324420 |
46 | sperm capacitation (GO:0048240) | 4.07339051 |
47 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 4.05788465 |
48 | response to hepatocyte growth factor (GO:0035728) | 4.05788465 |
49 | bicarbonate transport (GO:0015701) | 4.05055415 |
50 | plasma lipoprotein particle assembly (GO:0034377) | 4.02175427 |
51 | cellular glucuronidation (GO:0052695) | 3.98023880 |
52 | regulation of cholesterol homeostasis (GO:2000188) | 3.94435209 |
53 | maintenance of gastrointestinal epithelium (GO:0030277) | 3.94217224 |
54 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 3.94165628 |
55 | protein-lipid complex assembly (GO:0065005) | 3.93567614 |
56 | adhesion of symbiont to host (GO:0044406) | 3.93396945 |
57 | membrane repolarization during action potential (GO:0086011) | 3.92705329 |
58 | complement activation, classical pathway (GO:0006958) | 3.89616468 |
59 | glucuronate metabolic process (GO:0019585) | 3.89335570 |
60 | uronic acid metabolic process (GO:0006063) | 3.89335570 |
61 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 3.87578080 |
62 | digestion (GO:0007586) | 3.86525521 |
63 | regulation of cGMP biosynthetic process (GO:0030826) | 3.86388740 |
64 | organ or tissue specific immune response (GO:0002251) | 3.84585259 |
65 | regulation of triglyceride catabolic process (GO:0010896) | 3.82119274 |
66 | modified amino acid transport (GO:0072337) | 3.80355082 |
67 | phospholipid efflux (GO:0033700) | 3.76534384 |
68 | regulation of cholesterol esterification (GO:0010872) | 3.75141707 |
69 | hormone catabolic process (GO:0042447) | 3.73785674 |
70 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.72712322 |
71 | ethanol oxidation (GO:0006069) | 3.72142927 |
72 | bile acid and bile salt transport (GO:0015721) | 3.70985402 |
73 | nitrogen cycle metabolic process (GO:0071941) | 3.68365002 |
74 | cholesterol homeostasis (GO:0042632) | 3.68339876 |
75 | epoxygenase P450 pathway (GO:0019373) | 3.66101883 |
76 | cell killing (GO:0001906) | 3.65705874 |
77 | ethanol metabolic process (GO:0006067) | 3.65607896 |
78 | regulation of cellular extravasation (GO:0002691) | 3.65392885 |
79 | sterol homeostasis (GO:0055092) | 3.64701771 |
80 | cGMP-mediated signaling (GO:0019934) | 3.60301769 |
81 | cGMP biosynthetic process (GO:0006182) | 3.60129526 |
82 | diacylglycerol metabolic process (GO:0046339) | 3.59004313 |
83 | transcytosis (GO:0045056) | 3.56791082 |
84 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.55422986 |
85 | primary alcohol catabolic process (GO:0034310) | 3.53341533 |
86 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.48284138 |
87 | lipoprotein transport (GO:0042953) | 3.48198380 |
88 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.48071175 |
89 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.48071175 |
90 | eosinophil chemotaxis (GO:0048245) | 3.46907240 |
91 | nucleoside diphosphate biosynthetic process (GO:0009133) | 3.45460312 |
92 | cholesterol transport (GO:0030301) | 3.43871163 |
93 | sterol transport (GO:0015918) | 3.43871163 |
94 | sulfate transmembrane transport (GO:1902358) | 3.42947996 |
95 | cholesterol efflux (GO:0033344) | 3.41846258 |
96 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.39737213 |
97 | homocysteine metabolic process (GO:0050667) | 3.37451582 |
98 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.33883209 |
99 | peptide catabolic process (GO:0043171) | 3.33328538 |
100 | sulfate transport (GO:0008272) | 3.33191724 |
101 | fat-soluble vitamin biosynthetic process (GO:0042362) | 3.33036229 |
102 | O-glycan processing (GO:0016266) | 3.30770733 |
103 | peptide hormone processing (GO:0016486) | 3.26131342 |
104 | filopodium assembly (GO:0046847) | 3.24944162 |
105 | striated muscle atrophy (GO:0014891) | 3.23133269 |
106 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 3.22724808 |
107 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.22108659 |
108 | epithelial structure maintenance (GO:0010669) | 3.22001532 |
109 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.18590181 |
110 | glucocorticoid biosynthetic process (GO:0006704) | 3.16792909 |
111 | desmosome organization (GO:0002934) | 3.16727273 |
112 | drinking behavior (GO:0042756) | 3.15460052 |
113 | regulation of cGMP metabolic process (GO:0030823) | 3.14411564 |
114 | fructose metabolic process (GO:0006000) | 3.14267032 |
115 | negative regulation of cholesterol transport (GO:0032375) | 3.13633662 |
116 | negative regulation of sterol transport (GO:0032372) | 3.13633662 |
117 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 3.12293126 |
118 | glycosphingolipid catabolic process (GO:0046479) | 3.12192290 |
119 | positive regulation of glycoprotein biosynthetic process (GO:0010560) | 3.11384113 |
120 | alkaloid metabolic process (GO:0009820) | 3.09931942 |
121 | proline biosynthetic process (GO:0006561) | 3.08924492 |
122 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.08073447 |
123 | eosinophil migration (GO:0072677) | 3.07881104 |
124 | sulfation (GO:0051923) | 3.07312481 |
125 | complement activation (GO:0006956) | 3.06204247 |
126 | sulfur compound transport (GO:0072348) | 3.05539791 |
127 | endocrine pancreas development (GO:0031018) | 3.05414245 |
128 | negative regulation of myotube differentiation (GO:0010832) | 3.04965814 |
129 | regulation of digestive system process (GO:0044058) | 3.03679911 |
130 | phospholipid scrambling (GO:0017121) | 3.03555098 |
131 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 3.03343084 |
132 | glycolipid catabolic process (GO:0019377) | 3.03054096 |
133 | arginine metabolic process (GO:0006525) | 3.02815328 |
134 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.01276683 |
135 | GDP-mannose metabolic process (GO:0019673) | 3.00656535 |
136 | tight junction assembly (GO:0070830) | 3.00020077 |
137 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 2.99642683 |
138 | regulation of actin nucleation (GO:0051125) | 2.99441639 |
139 | protein targeting to Golgi (GO:0000042) | 2.98868547 |
140 | positive regulation of glycoprotein metabolic process (GO:1903020) | 2.95666689 |
141 | thyroid hormone metabolic process (GO:0042403) | 2.95621106 |
142 | negative regulation of steroid metabolic process (GO:0045939) | 2.93709375 |
143 | positive regulation of establishment of protein localization to plasma membrane (GO:0090004) | 2.93511982 |
144 | cellular response to pH (GO:0071467) | 2.89118606 |
145 | labyrinthine layer development (GO:0060711) | 2.86590619 |
146 | glycosylceramide metabolic process (GO:0006677) | 2.86544124 |
147 | sodium ion homeostasis (GO:0055078) | 2.83479065 |
148 | auditory receptor cell differentiation (GO:0042491) | 2.76356570 |
149 | sexual reproduction (GO:0019953) | 2.75885518 |
150 | positive regulation of cGMP biosynthetic process (GO:0030828) | 2.73498450 |
151 | receptor recycling (GO:0001881) | 2.71902705 |
152 | nucleotide-sugar biosynthetic process (GO:0009226) | 2.69987160 |
153 | arginine catabolic process (GO:0006527) | 2.64969591 |
154 | thrombin receptor signaling pathway (GO:0070493) | 2.64404633 |
155 | drug metabolic process (GO:0017144) | 2.63745307 |
156 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.63292381 |
157 | positive regulation of systemic arterial blood pressure (GO:0003084) | 2.61720289 |
158 | negative regulation of leukocyte chemotaxis (GO:0002689) | 2.57277429 |
159 | intestinal absorption (GO:0050892) | 12.0078215 |
160 | intestinal cholesterol absorption (GO:0030299) | 10.2385966 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 8.90154072 |
2 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 6.01691285 |
3 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 4.17633036 |
4 | GATA4_25053715_ChIP-Seq_YYC3_Human | 3.38588158 |
5 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 3.21014212 |
6 | * GATA6_25053715_ChIP-Seq_YYC3_Human | 3.16133159 |
7 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.92675592 |
8 | SOX2_20726797_ChIP-Seq_SW620_Human | 2.83435122 |
9 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.79227953 |
10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.70055233 |
11 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.65151926 |
12 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.54360485 |
13 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.49692240 |
14 | GATA1_22025678_ChIP-Seq_K562_Human | 2.37217776 |
15 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.30366424 |
16 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.15853665 |
17 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 2.15476183 |
18 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.14281427 |
19 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.13510677 |
20 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 2.03869777 |
21 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.98008373 |
22 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.95369265 |
23 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.94403128 |
24 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.93526386 |
25 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.90611020 |
26 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.87214675 |
27 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.84102212 |
28 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.80110091 |
29 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.78584375 |
30 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.74262984 |
31 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.72565198 |
32 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.71577636 |
33 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.70495144 |
34 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.66590531 |
35 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.66042534 |
36 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.64687991 |
37 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.64357123 |
38 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.64051425 |
39 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.63676377 |
40 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.63610820 |
41 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.63553167 |
42 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.52707938 |
43 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.52145901 |
44 | ATF3_27146783_Chip-Seq_COLON_Human | 1.50625948 |
45 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.49013058 |
46 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.46200550 |
47 | TP53_16413492_ChIP-PET_HCT116_Human | 1.43182690 |
48 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.41471251 |
49 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.40057066 |
50 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.39784437 |
51 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.38428947 |
52 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.37676263 |
53 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.35218148 |
54 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.35001061 |
55 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.33656292 |
56 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.26093664 |
57 | GATA2_19941826_ChIP-Seq_K562_Human | 1.25577117 |
58 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.25377883 |
59 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.19785616 |
60 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.17105824 |
61 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.16702470 |
62 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.16078964 |
63 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.15188643 |
64 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.14901984 |
65 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.14803248 |
66 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.14639575 |
67 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.12372948 |
68 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 1.11525845 |
69 | * FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.10151384 |
70 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.10085426 |
71 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.09466427 |
72 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.09431244 |
73 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.08831790 |
74 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.08831790 |
75 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.07125175 |
76 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.06785069 |
77 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06555950 |
78 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.06494810 |
79 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.05329506 |
80 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.04137320 |
81 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.00725201 |
82 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.00282839 |
83 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.99723556 |
84 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.96921658 |
85 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.96693391 |
86 | SA1_27219007_Chip-Seq_Bcells_Human | 0.96610152 |
87 | FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96303942 |
88 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.95073418 |
89 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.94168965 |
90 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.93588681 |
91 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.92495842 |
92 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.92495842 |
93 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.92341257 |
94 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.92325221 |
95 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.92241874 |
96 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91497086 |
97 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.91082462 |
98 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.90314062 |
99 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.89432143 |
100 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.88660561 |
101 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.87919172 |
102 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.87462449 |
103 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.86859862 |
104 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.86711184 |
105 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.85929287 |
106 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.85853555 |
107 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.85711682 |
108 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.85556556 |
109 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.85026282 |
110 | * CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.85009539 |
111 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.84960998 |
112 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.84526756 |
113 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.83036975 |
114 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.82737839 |
115 | GATA1_19941826_ChIP-Seq_K562_Human | 0.82678932 |
116 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.82544397 |
117 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.81991668 |
118 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.81879076 |
119 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.81812948 |
120 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.80815644 |
121 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.80424718 |
122 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.80178256 |
123 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.78014687 |
124 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.77688816 |
125 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.77570233 |
126 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.77253594 |
127 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.75488364 |
128 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.75426090 |
129 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.75174804 |
130 | * STAT1_17558387_ChIP-Seq_HELA_Human | 0.74668019 |
131 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.73901927 |
132 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.73695200 |
133 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.72590641 |
134 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.71009951 |
135 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.70977855 |
136 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.70785929 |
137 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.70080299 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 8.35096496 |
2 | MP0001666_abnormal_nutrient_absorption | 5.32415600 |
3 | MP0010234_abnormal_vibrissa_follicle | 4.47873409 |
4 | MP0004264_abnormal_extraembryonic_tissu | 3.96776995 |
5 | MP0000462_abnormal_digestive_system | 3.82231965 |
6 | MP0002139_abnormal_hepatobiliary_system | 3.76324075 |
7 | MP0005085_abnormal_gallbladder_physiolo | 3.48914157 |
8 | MP0003300_gastrointestinal_ulcer | 3.17844489 |
9 | MP0003866_abnormal_defecation | 3.09414724 |
10 | MP0003183_abnormal_peptide_metabolism | 2.95959109 |
11 | MP0009840_abnormal_foam_cell | 2.89083947 |
12 | MP0003252_abnormal_bile_duct | 2.87168356 |
13 | MP0001873_stomach_inflammation | 2.58295785 |
14 | MP0000537_abnormal_urethra_morphology | 2.57079783 |
15 | MP0005365_abnormal_bile_salt | 2.33296227 |
16 | MP0001663_abnormal_digestive_system | 2.32302802 |
17 | MP0010155_abnormal_intestine_physiology | 2.31478078 |
18 | MP0010352_gastrointestinal_tract_polyps | 2.28145332 |
19 | MP0010329_abnormal_lipoprotein_level | 2.27037952 |
20 | MP0008004_abnormal_stomach_pH | 2.20617773 |
21 | MP0005381_digestive/alimentary_phenotyp | 2.18715033 |
22 | MP0008875_abnormal_xenobiotic_pharmacok | 2.12980218 |
23 | MP0000490_abnormal_crypts_of | 2.06540263 |
24 | MP0002822_catalepsy | 2.03907361 |
25 | MP0009379_abnormal_foot_pigmentation | 2.00620542 |
26 | MP0001664_abnormal_digestion | 1.96553996 |
27 | MP0004858_abnormal_nervous_system | 1.94882103 |
28 | MP0005409_darkened_coat_color | 1.93034852 |
29 | MP0000477_abnormal_intestine_morphology | 1.91791987 |
30 | MP0003724_increased_susceptibility_to | 1.85931411 |
31 | MP0004019_abnormal_vitamin_homeostasis | 1.82586179 |
32 | MP0004782_abnormal_surfactant_physiolog | 1.77223943 |
33 | MP0005670_abnormal_white_adipose | 1.75323933 |
34 | MP0000538_abnormal_urinary_bladder | 1.74898063 |
35 | MP0004147_increased_porphyrin_level | 1.66949245 |
36 | MP0002254_reproductive_system_inflammat | 1.65805219 |
37 | MP0002138_abnormal_hepatobiliary_system | 1.65033211 |
38 | MP0000465_gastrointestinal_hemorrhage | 1.52440821 |
39 | MP0003705_abnormal_hypodermis_morpholog | 1.48272602 |
40 | MP0009780_abnormal_chondrocyte_physiolo | 1.35886674 |
41 | MP0003303_peritoneal_inflammation | 1.35209222 |
42 | MP0002796_impaired_skin_barrier | 1.32876439 |
43 | MP0002089_abnormal_postnatal_growth/wei | 1.31672105 |
44 | MP0002166_altered_tumor_susceptibility | 1.26711181 |
45 | MP0004043_abnormal_pH_regulation | 1.26248814 |
46 | MP0005377_hearing/vestibular/ear_phenot | 1.25675925 |
47 | MP0003878_abnormal_ear_physiology | 1.25675925 |
48 | MP0005084_abnormal_gallbladder_morpholo | 1.25446674 |
49 | MP0005448_abnormal_energy_balance | 1.24358291 |
50 | MP0008872_abnormal_physiological_respon | 1.22880848 |
51 | MP0005451_abnormal_body_composition | 1.22337824 |
52 | MP0002277_abnormal_respiratory_mucosa | 1.19759575 |
53 | MP0000230_abnormal_systemic_arterial | 1.17964269 |
54 | MP0006054_spinal_hemorrhage | 1.14073862 |
55 | MP0005165_increased_susceptibility_to | 1.13404743 |
56 | MP0002163_abnormal_gland_morphology | 1.12490166 |
57 | MP0001790_abnormal_immune_system | 1.10767540 |
58 | MP0005387_immune_system_phenotype | 1.10767540 |
59 | MP0000613_abnormal_salivary_gland | 1.08083662 |
60 | MP0003436_decreased_susceptibility_to | 1.07394642 |
61 | MP0010678_abnormal_skin_adnexa | 1.07214829 |
62 | MP0002009_preneoplasia | 1.05610384 |
63 | MP0001849_ear_inflammation | 1.04731081 |
64 | MP0009785_altered_susceptibility_to | 1.02892399 |
65 | MP0009643_abnormal_urine_homeostasis | 1.02424009 |
66 | MP0001485_abnormal_pinna_reflex | 1.00954853 |
67 | MP0001756_abnormal_urination | 1.00030314 |
68 | MP0008775_abnormal_heart_ventricle | 1.00021901 |
69 | MP0004215_abnormal_myocardial_fiber | 0.99962941 |
70 | MP0003806_abnormal_nucleotide_metabolis | 0.99955103 |
71 | MP0005025_abnormal_response_to | 0.99797907 |
72 | MP0000566_synostosis | 0.99052285 |
73 | MP0001845_abnormal_inflammatory_respons | 0.98873353 |
74 | MP0001188_hyperpigmentation | 0.98371610 |
75 | MP0003693_abnormal_embryo_hatching | 0.97914103 |
76 | MP0009053_abnormal_anal_canal | 0.97126165 |
77 | MP0001533_abnormal_skeleton_physiology | 0.96409953 |
78 | MP0009384_cardiac_valve_regurgitation | 0.95296415 |
79 | MP0003329_amyloid_beta_deposits | 0.93241259 |
80 | MP0002896_abnormal_bone_mineralization | 0.93204539 |
81 | MP0000470_abnormal_stomach_morphology | 0.91568602 |
82 | MP0004270_analgesia | 0.90059491 |
83 | MP0002098_abnormal_vibrissa_morphology | 0.89557167 |
84 | MP0005332_abnormal_amino_acid | 0.89228211 |
85 | MP0003453_abnormal_keratinocyte_physiol | 0.88492837 |
86 | MP0004484_altered_response_of | 0.88294303 |
87 | MP0000609_abnormal_liver_physiology | 0.85887450 |
88 | MP0002006_tumorigenesis | 0.85120994 |
89 | MP0002118_abnormal_lipid_homeostasis | 0.84976069 |
90 | MP0002132_abnormal_respiratory_system | 0.82535625 |
91 | MP0003119_abnormal_digestive_system | 0.82202728 |
92 | MP0005666_abnormal_adipose_tissue | 0.81518562 |
93 | MP0002971_abnormal_brown_adipose | 0.80443795 |
94 | MP0005166_decreased_susceptibility_to | 0.80154884 |
95 | MP0000249_abnormal_blood_vessel | 0.79843012 |
96 | MP0005501_abnormal_skin_physiology | 0.79671288 |
97 | MP0001765_abnormal_ion_homeostasis | 0.79255600 |
98 | MP0001501_abnormal_sleep_pattern | 0.77604916 |
99 | MP0003283_abnormal_digestive_organ | 0.77505696 |
100 | MP0000467_abnormal_esophagus_morphology | 0.76696391 |
101 | MP0006082_CNS_inflammation | 0.75843653 |
102 | MP0004947_skin_inflammation | 0.75219637 |
103 | MP0002998_abnormal_bone_remodeling | 0.74919420 |
104 | MP0009115_abnormal_fat_cell | 0.74110711 |
105 | MP0005367_renal/urinary_system_phenotyp | 0.73089786 |
106 | MP0000516_abnormal_urinary_system | 0.73089786 |
107 | MP0005058_abnormal_lysosome_morphology | 0.70564748 |
108 | MP0002876_abnormal_thyroid_physiology | 0.68034170 |
109 | MP0001835_abnormal_antigen_presentation | 0.67375842 |
110 | MP0005023_abnormal_wound_healing | 0.67143502 |
111 | MP0000604_amyloidosis | 0.67084287 |
112 | MP0009697_abnormal_copulation | 0.65519051 |
113 | MP0001216_abnormal_epidermal_layer | 0.63796324 |
114 | MP0005167_abnormal_blood-brain_barrier | 0.63648232 |
115 | MP0003315_abnormal_perineum_morphology | 0.61724982 |
116 | MP0005385_cardiovascular_system_phenoty | 0.60788132 |
117 | MP0001544_abnormal_cardiovascular_syste | 0.60788132 |
118 | MP0003075_altered_response_to | 0.60757278 |
119 | MP0000013_abnormal_adipose_tissue | 0.60280500 |
120 | MP0003868_abnormal_feces_composition | 0.60224793 |
121 | MP0006138_congestive_heart_failure | 0.60204872 |
122 | MP0002148_abnormal_hypersensitivity_rea | 0.60023066 |
123 | MP0005636_abnormal_mineral_homeostasis | 0.58900263 |
124 | MP0005319_abnormal_enzyme/_coenzyme | 0.57502520 |
125 | MP0000678_abnormal_parathyroid_gland | 0.57358001 |
126 | MP0001764_abnormal_homeostasis | 0.56631948 |
127 | MP0010386_abnormal_urinary_bladder | 0.56388099 |
128 | MP0003718_maternal_effect | 0.56318437 |
129 | MP0003191_abnormal_cellular_cholesterol | 0.54723676 |
130 | MP0005187_abnormal_penis_morphology | 0.53832301 |
131 | MP0005266_abnormal_metabolism | 0.51797971 |
132 | MP0005310_abnormal_salivary_gland | 0.51185741 |
133 | MP0003950_abnormal_plasma_membrane | 0.51042119 |
134 | MP0002136_abnormal_kidney_physiology | 0.48855486 |
135 | MP0009765_abnormal_xenobiotic_induced | 0.48585115 |
136 | MP0003879_abnormal_hair_cell | 0.47912785 |
137 | MP0000579_abnormal_nail_morphology | 0.45102096 |
138 | MP0002060_abnormal_skin_morphology | 0.41728841 |
139 | MP0009642_abnormal_blood_homeostasis | 0.40982612 |
140 | MP0005379_endocrine/exocrine_gland_phen | 0.40920333 |
141 | MP0003638_abnormal_response/metabolism_ | 0.39711686 |
142 | MP0003045_fibrosis | 0.38836655 |
143 | MP0001191_abnormal_skin_condition | 0.37589388 |
144 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.35804329 |
145 | MP0003787_abnormal_imprinting | 0.35723134 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperactive renin-angiotensin system (HP:0000841) | 7.49425583 |
2 | Decreased circulating renin level (HP:0003351) | 6.33362390 |
3 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 6.17469085 |
4 | Conjugated hyperbilirubinemia (HP:0002908) | 5.98037631 |
5 | Right ventricular cardiomyopathy (HP:0011663) | 5.95749308 |
6 | Acanthocytosis (HP:0001927) | 5.75138217 |
7 | Malnutrition (HP:0004395) | 5.73498118 |
8 | Metabolic alkalosis (HP:0200114) | 5.70814951 |
9 | Abnormality of renin-angiotensin system (HP:0000847) | 5.39397984 |
10 | Hypobetalipoproteinemia (HP:0003563) | 5.37324728 |
11 | Rectal prolapse (HP:0002035) | 4.79785969 |
12 | Congenital sensorineural hearing impairment (HP:0008527) | 4.55180060 |
13 | Alkalosis (HP:0001948) | 4.50271708 |
14 | Ventricular fibrillation (HP:0001663) | 4.31130687 |
15 | Systemic lupus erythematosus (HP:0002725) | 4.29599545 |
16 | Fat malabsorption (HP:0002630) | 4.04059431 |
17 | Abdominal distention (HP:0003270) | 3.98209218 |
18 | Pigmentary retinal degeneration (HP:0001146) | 3.80962605 |
19 | Gastrointestinal dysmotility (HP:0002579) | 3.76457369 |
20 | Chronic diarrhea (HP:0002028) | 3.72432277 |
21 | Abnormal biliary tract morphology (HP:0012440) | 3.71953542 |
22 | Hyperaldosteronism (HP:0000859) | 3.66936765 |
23 | Hydroxyprolinuria (HP:0003080) | 3.62918030 |
24 | Abnormality of proline metabolism (HP:0010907) | 3.62918030 |
25 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 3.59030070 |
26 | Intrahepatic cholestasis (HP:0001406) | 3.53247604 |
27 | Autoimmune thrombocytopenia (HP:0001973) | 3.47661998 |
28 | Glycosuria (HP:0003076) | 3.45963338 |
29 | Abnormality of urine glucose concentration (HP:0011016) | 3.45963338 |
30 | Hemorrhage of the eye (HP:0011885) | 3.39307838 |
31 | Widely patent fontanelles and sutures (HP:0004492) | 3.37538093 |
32 | Abnormality of vitamin B metabolism (HP:0004340) | 3.33150808 |
33 | Poikilocytosis (HP:0004447) | 3.28102800 |
34 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 3.23565205 |
35 | Abnormality of small intestinal villus morphology (HP:0011472) | 3.20846974 |
36 | Villous atrophy (HP:0011473) | 3.20846974 |
37 | Male infertility (HP:0003251) | 3.20361040 |
38 | Dehydration (HP:0001944) | 3.18221774 |
39 | Abnormality of the gastric mucosa (HP:0004295) | 3.10127332 |
40 | Abnormal glucose tolerance (HP:0001952) | 3.04644270 |
41 | Autoimmune hemolytic anemia (HP:0001890) | 2.99545427 |
42 | Abnormality of complement system (HP:0005339) | 2.97692727 |
43 | Abnormality of vitamin metabolism (HP:0100508) | 2.94176611 |
44 | Abnormal tarsal ossification (HP:0008369) | 2.91592447 |
45 | Hypokalemia (HP:0002900) | 2.90702788 |
46 | Abnormality of chloride homeostasis (HP:0011422) | 2.89777284 |
47 | Hyponatremia (HP:0002902) | 2.87942898 |
48 | Complement deficiency (HP:0004431) | 2.87167488 |
49 | Hypolipoproteinemia (HP:0010981) | 2.86938752 |
50 | Eczematoid dermatitis (HP:0000976) | 2.86221441 |
51 | Progressive sensorineural hearing impairment (HP:0000408) | 2.84957480 |
52 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.81452459 |
53 | Pustule (HP:0200039) | 2.78892324 |
54 | Syncope (HP:0001279) | 2.78862626 |
55 | Increased mean platelet volume (HP:0011877) | 2.77922130 |
56 | Glomerulonephritis (HP:0000099) | 2.73647577 |
57 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.72300579 |
58 | Flattened epiphyses (HP:0003071) | 2.70780316 |
59 | Cupped ribs (HP:0000887) | 2.66851088 |
60 | Abnormality of potassium homeostasis (HP:0011042) | 2.62443451 |
61 | Late onset (HP:0003584) | 2.56493528 |
62 | Progressive hearing impairment (HP:0001730) | 2.53014127 |
63 | Wide cranial sutures (HP:0010537) | 2.51629346 |
64 | Biliary tract neoplasm (HP:0100574) | 2.51566755 |
65 | Woolly hair (HP:0002224) | 2.50959875 |
66 | Palpitations (HP:0001962) | 2.44811775 |
67 | Facial shape deformation (HP:0011334) | 2.40554283 |
68 | Potter facies (HP:0002009) | 2.40554283 |
69 | Micronodular cirrhosis (HP:0001413) | 2.40478946 |
70 | Pili torti (HP:0003777) | 2.40237348 |
71 | Fragile skin (HP:0001030) | 2.40208471 |
72 | Abnormal platelet volume (HP:0011876) | 2.38369318 |
73 | Nephritis (HP:0000123) | 2.38080682 |
74 | Hyperkalemia (HP:0002153) | 2.37846975 |
75 | Visceral angiomatosis (HP:0100761) | 2.37025354 |
76 | Uterine neoplasm (HP:0010784) | 2.28113931 |
77 | Prolonged QT interval (HP:0001657) | 2.28085826 |
78 | Nephrolithiasis (HP:0000787) | 2.28081021 |
79 | Milia (HP:0001056) | 2.27904703 |
80 | Hypotension (HP:0002615) | 2.27220562 |
81 | Abnormality of carpal bone ossification (HP:0006257) | 2.27198885 |
82 | Neonatal short-limb short stature (HP:0008921) | 2.25317696 |
83 | Posterior subcapsular cataract (HP:0007787) | 2.24426576 |
84 | Hyperphosphaturia (HP:0003109) | 2.24424254 |
85 | Abnormality of sodium homeostasis (HP:0010931) | 2.23989291 |
86 | Abnormality of the 1st metacarpal (HP:0010009) | 2.21496296 |
87 | Thin bony cortex (HP:0002753) | 2.20670046 |
88 | Adrenal overactivity (HP:0002717) | 2.20429974 |
89 | Hypercholesterolemia (HP:0003124) | 2.19804367 |
90 | Bundle branch block (HP:0011710) | 2.18275224 |
91 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 2.17374639 |
92 | Confusion (HP:0001289) | 2.15664297 |
93 | Exocrine pancreatic insufficiency (HP:0001738) | 2.11964617 |
94 | Hyperglycinuria (HP:0003108) | 2.09511725 |
95 | Hemangiomatosis (HP:0007461) | 2.08744411 |
96 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.08344716 |
97 | Malignant gastrointestinal tract tumors (HP:0006749) | 2.07246702 |
98 | Gastrointestinal carcinoma (HP:0002672) | 2.07246702 |
99 | Nausea (HP:0002018) | 2.05728827 |
100 | Abnormality of purine metabolism (HP:0004352) | 2.05242312 |
101 | Hyperbilirubinemia (HP:0002904) | 2.04184384 |
102 | Ventricular arrhythmia (HP:0004308) | 2.03853657 |
103 | Urethral obstruction (HP:0000796) | 2.03060337 |
104 | Hypercalciuria (HP:0002150) | 2.02557297 |
105 | Hyperammonemia (HP:0001987) | 2.01472434 |
106 | Reticulocytosis (HP:0001923) | 2.00600821 |
107 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.00508764 |
108 | Dicarboxylic aciduria (HP:0003215) | 2.00508764 |
109 | Ileus (HP:0002595) | 11.1649587 |
110 | Abnormal hair laboratory examination (HP:0003328) | 1.98522038 |
111 | Growth hormone excess (HP:0000845) | 1.97344179 |
112 | Focal segmental glomerulosclerosis (HP:0000097) | 1.97161389 |
113 | Cerebral palsy (HP:0100021) | 1.95200789 |
114 | Neoplasm of the small intestine (HP:0100833) | 1.95082284 |
115 | Spontaneous hematomas (HP:0007420) | 1.94430459 |
116 | Microretrognathia (HP:0000308) | 1.94143841 |
117 | Abnormal foot bone ossification (HP:0010675) | 1.93562327 |
118 | Proximal tubulopathy (HP:0000114) | 1.93415358 |
119 | Neoplasm of the rectum (HP:0100743) | 1.93085523 |
120 | Abnormal urine phosphate concentration (HP:0012599) | 1.90094383 |
121 | Abnormality of the right ventricle (HP:0001707) | 1.89737756 |
122 | Hematochezia (HP:0002573) | 1.88988424 |
123 | Metabolic acidosis (HP:0001942) | 1.88797763 |
124 | Xanthomatosis (HP:0000991) | 1.88399403 |
125 | Symptomatic seizures (HP:0011145) | 1.87694695 |
126 | Ventricular tachycardia (HP:0004756) | 1.87657697 |
127 | Partial duplication of thumb phalanx (HP:0009944) | 1.87482134 |
128 | Hyperparathyroidism (HP:0000843) | 1.86291904 |
129 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.85735881 |
130 | Goiter (HP:0000853) | 1.85475657 |
131 | Abnormality of the nasal mucosa (HP:0000433) | 1.85218241 |
132 | Renal tubular acidosis (HP:0001947) | 1.84811893 |
133 | Amyloidosis (HP:0011034) | 1.84270583 |
134 | Ankyloglossia (HP:0010296) | 1.84116317 |
135 | Gingivitis (HP:0000230) | 1.81723238 |
136 | Flat capital femoral epiphysis (HP:0003370) | 1.81177653 |
137 | Petechiae (HP:0000967) | 1.80738841 |
138 | Curly hair (HP:0002212) | 1.80662680 |
139 | Flat acetabular roof (HP:0003180) | 1.79835451 |
140 | Hyperphosphatemia (HP:0002905) | 1.79746888 |
141 | Protuberant abdomen (HP:0001538) | 1.79158648 |
142 | Polycythemia (HP:0001901) | 1.77714434 |
143 | Abnormal ossification of hand bones (HP:0005921) | 1.77225770 |
144 | Abnormal hand bone ossification (HP:0010660) | 1.76884253 |
145 | Severe short stature (HP:0003510) | 1.76681239 |
146 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.75871265 |
147 | Distal lower limb amyotrophy (HP:0008944) | 1.73202771 |
148 | Pancreatitis (HP:0001733) | 1.72823779 |
149 | Plantar hyperkeratosis (HP:0007556) | 1.72525256 |
150 | Mesangial abnormality (HP:0001966) | 1.72298120 |
151 | Bone pain (HP:0002653) | 1.70306720 |
152 | Chorioretinal atrophy (HP:0000533) | 1.69599267 |
153 | Hypophosphatemia (HP:0002148) | 1.69536582 |
154 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.68414462 |
Rank | Gene Set | Z-score |
---|---|---|
1 | LMTK2 | 9.02438962 |
2 | FRK | 6.03108268 |
3 | ACVR1B | 5.25462131 |
4 | PRKG2 | 4.16431682 |
5 | MST4 | 4.15998619 |
6 | MST1R | 3.77406993 |
7 | EPHA2 | 2.89004372 |
8 | NME1 | 2.43430688 |
9 | GRK6 | 2.30140199 |
10 | RIPK1 | 2.17861983 |
11 | MAP2K2 | 2.16605086 |
12 | MAP3K10 | 2.10549421 |
13 | NUAK1 | 2.08943395 |
14 | EPHA3 | 2.07794774 |
15 | EPHB2 | 2.05294535 |
16 | STK39 | 1.95091655 |
17 | MAP3K2 | 1.66472921 |
18 | PTK6 | 1.66089633 |
19 | PRPF4B | 1.63567860 |
20 | TAOK3 | 1.55988451 |
21 | STK24 | 1.50861345 |
22 | MAP2K6 | 1.48142488 |
23 | TYK2 | 1.35440322 |
24 | TESK2 | 1.33556484 |
25 | MET | 1.31534877 |
26 | PIK3CA | 1.18229139 |
27 | DMPK | 1.18087444 |
28 | MAP3K12 | 1.11608957 |
29 | CDC42BPA | 1.06118175 |
30 | TESK1 | 1.04346953 |
31 | FGFR3 | 1.03643155 |
32 | ERN1 | 1.03242620 |
33 | ERBB2 | 1.00956732 |
34 | NLK | 0.99155208 |
35 | OXSR1 | 0.90004106 |
36 | PBK | 0.87354137 |
37 | LATS1 | 0.86316069 |
38 | PRKCI | 0.84372042 |
39 | TTK | 0.83837440 |
40 | SCYL2 | 0.83016665 |
41 | MAP3K8 | 0.82367196 |
42 | STK10 | 0.82321468 |
43 | WNK4 | 0.79621104 |
44 | MAP3K11 | 0.79517619 |
45 | TRIB3 | 0.76698271 |
46 | PTK2 | 0.75756377 |
47 | TGFBR2 | 0.73270144 |
48 | PKN2 | 0.72211018 |
49 | PRKAA2 | 0.70116835 |
50 | MYLK | 0.69073078 |
51 | MAPK11 | 0.68784612 |
52 | MAP4K1 | 0.68414938 |
53 | ZAP70 | 0.68093206 |
54 | AKT3 | 0.67467864 |
55 | SMG1 | 0.66218360 |
56 | MAP3K7 | 0.65360488 |
57 | ABL2 | 0.65294454 |
58 | DDR2 | 0.64067168 |
59 | TAOK1 | 0.63107922 |
60 | IRAK1 | 0.62489907 |
61 | EPHB1 | 0.62482659 |
62 | FER | 0.61052849 |
63 | PDGFRA | 0.59893491 |
64 | JAK2 | 0.59220381 |
65 | JAK1 | 0.58649937 |
66 | MAP3K1 | 0.57684105 |
67 | PDK4 | 0.56228543 |
68 | PDK3 | 0.56228543 |
69 | MAP3K9 | 0.55070725 |
70 | CDK12 | 0.53813239 |
71 | EEF2K | 0.53522618 |
72 | MATK | 0.53023271 |
73 | RIPK4 | 0.52941126 |
74 | DYRK1B | 0.52125660 |
75 | AURKB | 0.51593755 |
76 | RET | 0.51310835 |
77 | KSR2 | 0.47727975 |
78 | MAP2K1 | 0.46877152 |
79 | PRKAA1 | 0.46068471 |
80 | BMX | 0.45816715 |
81 | GRK1 | 0.44963673 |
82 | TBK1 | 0.44777298 |
83 | ROCK1 | 0.44421614 |
84 | EPHA4 | 0.43823480 |
85 | RPS6KA2 | 0.43141737 |
86 | PAK3 | 0.39114438 |
87 | PAK4 | 0.37175267 |
88 | IKBKE | 0.36787884 |
89 | MAPKAPK2 | 0.34821332 |
90 | CSNK1E | 0.34350858 |
91 | MAP3K3 | 0.33895137 |
92 | MUSK | 0.33832314 |
93 | PDPK1 | 0.32850907 |
94 | FYN | 0.32733232 |
95 | MAP3K6 | 0.32434241 |
96 | MAPK7 | 0.32009290 |
97 | RPS6KB2 | 0.30753565 |
98 | RPS6KL1 | 0.30750599 |
99 | RPS6KC1 | 0.30750599 |
100 | CAMK2G | 0.30530941 |
101 | BMPR2 | 0.30117060 |
102 | CAMK2B | 0.29976496 |
103 | LRRK2 | 0.29893685 |
104 | TTN | 0.29825287 |
105 | CAMK2D | 0.29654031 |
106 | PDK2 | 0.28745581 |
107 | JAK3 | 0.28331891 |
108 | TNIK | 0.28214222 |
109 | BCR | 0.27834083 |
110 | CSNK1A1 | 0.27361448 |
111 | PAK1 | 0.27359111 |
112 | CSK | 0.26783942 |
113 | PAK2 | 0.25595198 |
114 | MAP3K14 | 0.25505440 |
115 | PRKCA | 0.24658200 |
116 | CDK19 | 0.23166088 |
117 | PIM2 | 0.23165247 |
118 | NEK1 | 0.22825412 |
119 | KIT | 0.22807641 |
120 | PRKCQ | 0.22650530 |
121 | MAPK15 | 0.22405929 |
122 | KSR1 | 0.22161149 |
123 | LYN | 0.21999146 |
124 | PRKCD | 0.21921832 |
125 | WNK1 | 0.21918969 |
126 | RAF1 | 0.21565671 |
127 | PDK1 | 0.21257562 |
128 | YES1 | 0.20846603 |
129 | RPS6KA6 | 0.20702464 |
130 | STK3 | 0.20656000 |
131 | GSK3A | 0.20554187 |
132 | AKT2 | 0.20421666 |
133 | SRC | 0.20347430 |
134 | PRKCZ | 0.19784593 |
135 | PRKACG | 0.18025879 |
136 | STK11 | 0.17107378 |
137 | TRPM7 | 0.15619187 |
138 | FGFR4 | 0.14833724 |
139 | PRKG1 | 0.14521332 |
140 | ICK | 0.14431851 |
141 | IRAK3 | 0.11983039 |
142 | PRKCB | 0.11869873 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 5.24438712 |
2 | Fat digestion and absorption_Homo sapiens_hsa04975 | 5.19033231 |
3 | Mineral absorption_Homo sapiens_hsa04978 | 3.70629097 |
4 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.38838943 |
5 | Renin-angiotensin system_Homo sapiens_hsa04614 | 3.27103711 |
6 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.97383203 |
7 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.90550407 |
8 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 2.85957317 |
9 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.74879801 |
10 | Galactose metabolism_Homo sapiens_hsa00052 | 2.73939475 |
11 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 2.36188843 |
12 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.28832288 |
13 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 2.27088184 |
14 | Bile secretion_Homo sapiens_hsa04976 | 2.25504354 |
15 | Histidine metabolism_Homo sapiens_hsa00340 | 2.05226581 |
16 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.86176794 |
17 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.84907142 |
18 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.83884311 |
19 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.83606713 |
20 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.76508031 |
21 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.71051011 |
22 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.56279900 |
23 | Asthma_Homo sapiens_hsa05310 | 1.42392028 |
24 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.34890075 |
25 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.30635310 |
26 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.30240235 |
27 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.28212819 |
28 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.27549093 |
29 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.27464269 |
30 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.27268082 |
31 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.19459694 |
32 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.18380538 |
33 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.13761878 |
34 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.11570786 |
35 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.07574069 |
36 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.07410432 |
37 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.05875834 |
38 | Other glycan degradation_Homo sapiens_hsa00511 | 1.04009906 |
39 | Tight junction_Homo sapiens_hsa04530 | 1.03906348 |
40 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.03407801 |
41 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.00218264 |
42 | Allograft rejection_Homo sapiens_hsa05330 | 0.99415937 |
43 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.97389147 |
44 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.94555135 |
45 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.93182518 |
46 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.92407799 |
47 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.89263773 |
48 | ABC transporters_Homo sapiens_hsa02010 | 0.87931657 |
49 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.87119207 |
50 | Carbon metabolism_Homo sapiens_hsa01200 | 0.82648776 |
51 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.82039347 |
52 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.80674495 |
53 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.77185276 |
54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.72165162 |
55 | Sulfur relay system_Homo sapiens_hsa04122 | 0.69532662 |
56 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.67326811 |
57 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.65036925 |
58 | Lysine degradation_Homo sapiens_hsa00310 | 0.62511708 |
59 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.61213242 |
60 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.59806185 |
61 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.58820790 |
62 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.58138185 |
63 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.54652137 |
64 | Leishmaniasis_Homo sapiens_hsa05140 | 0.54146935 |
65 | Pertussis_Homo sapiens_hsa05133 | 0.53935797 |
66 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.53858736 |
67 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.52551309 |
68 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51844289 |
69 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.48528726 |
70 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.48410370 |
71 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.47538809 |
72 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.47469636 |
73 | Retinol metabolism_Homo sapiens_hsa00830 | 0.47421957 |
74 | Salmonella infection_Homo sapiens_hsa05132 | 0.47413822 |
75 | Salivary secretion_Homo sapiens_hsa04970 | 0.47073867 |
76 | Viral myocarditis_Homo sapiens_hsa05416 | 0.46706136 |
77 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.46210211 |
78 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.45731596 |
79 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.44538254 |
80 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.43946941 |
81 | Adherens junction_Homo sapiens_hsa04520 | 0.43533544 |
82 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.43346626 |
83 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.43210729 |
84 | Thyroid cancer_Homo sapiens_hsa05216 | 0.40291759 |
85 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39596322 |
86 | Insulin resistance_Homo sapiens_hsa04931 | 0.39489241 |
87 | Bladder cancer_Homo sapiens_hsa05219 | 0.36796697 |
88 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.35392056 |
89 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.34642257 |
90 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.34170111 |
91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32620929 |
92 | Insulin secretion_Homo sapiens_hsa04911 | 0.32507779 |
93 | Hepatitis C_Homo sapiens_hsa05160 | 0.32333903 |
94 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.31379058 |
95 | Peroxisome_Homo sapiens_hsa04146 | 0.31313772 |
96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.30002762 |
97 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.29151730 |
98 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.28316293 |
99 | Renin secretion_Homo sapiens_hsa04924 | 0.25343696 |
100 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.25119619 |
101 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.24844619 |
102 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.24604825 |
103 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.22464531 |
104 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.21786314 |
105 | Amoebiasis_Homo sapiens_hsa05146 | 0.21091902 |
106 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.20542791 |
107 | Endometrial cancer_Homo sapiens_hsa05213 | 0.19759202 |
108 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.18900790 |
109 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.18692908 |
110 | Metabolic pathways_Homo sapiens_hsa01100 | 0.18305915 |
111 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.16135981 |
112 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.14486706 |
113 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.13499538 |
114 | Tuberculosis_Homo sapiens_hsa05152 | 0.12942431 |
115 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.12358501 |
116 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.12068551 |
117 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.11265484 |
118 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.11125683 |
119 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.10752057 |
120 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.10480701 |
121 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.09834561 |
122 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.08188842 |
123 | Gap junction_Homo sapiens_hsa04540 | 0.07026604 |
124 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.06905781 |
125 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.06676673 |
126 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.06169845 |
127 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.05851700 |
128 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.05744690 |
129 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.05400264 |
130 | Long-term depression_Homo sapiens_hsa04730 | 0.05080023 |
131 | Influenza A_Homo sapiens_hsa05164 | 0.03600490 |
132 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.03388596 |
133 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.01557790 |