Rank | Gene Set | Z-score |
---|---|---|
1 | activated T cell proliferation (GO:0050798) | 5.12455294 |
2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.01473645 |
3 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.67108523 |
4 | regulation of gamma-delta T cell activation (GO:0046643) | 4.35253699 |
5 | detection of molecule of bacterial origin (GO:0032490) | 4.35237551 |
6 | regulation of protein activation cascade (GO:2000257) | 4.20159999 |
7 | regulation of complement activation (GO:0030449) | 4.17172191 |
8 | negative T cell selection (GO:0043383) | 4.13535515 |
9 | positive thymic T cell selection (GO:0045059) | 4.11845010 |
10 | positive T cell selection (GO:0043368) | 4.10682186 |
11 | regulation of T cell tolerance induction (GO:0002664) | 3.98184031 |
12 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.92120842 |
13 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.92120842 |
14 | regulation of apoptotic cell clearance (GO:2000425) | 3.88454510 |
15 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.82944635 |
16 | T cell selection (GO:0045058) | 3.73326280 |
17 | negative regulation of fibrinolysis (GO:0051918) | 3.72414615 |
18 | negative thymic T cell selection (GO:0045060) | 3.67297138 |
19 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.65612856 |
20 | leukocyte aggregation (GO:0070486) | 3.64214691 |
21 | low-density lipoprotein particle remodeling (GO:0034374) | 3.53378312 |
22 | thymic T cell selection (GO:0045061) | 3.52512842 |
23 | tolerance induction (GO:0002507) | 3.45794297 |
24 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.44832890 |
25 | cellular extravasation (GO:0045123) | 3.41589934 |
26 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.37261968 |
27 | negative regulation of protein activation cascade (GO:2000258) | 3.36670212 |
28 | negative regulation of cell killing (GO:0031342) | 3.33556607 |
29 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.33556607 |
30 | histone H3-K36 demethylation (GO:0070544) | 3.27350063 |
31 | regulation of fibrinolysis (GO:0051917) | 3.23048585 |
32 | detection of external biotic stimulus (GO:0098581) | 3.12625728 |
33 | T cell receptor signaling pathway (GO:0050852) | 3.12313835 |
34 | macrophage activation involved in immune response (GO:0002281) | 3.11427577 |
35 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.09106603 |
36 | regulation of macrophage chemotaxis (GO:0010758) | 3.08400756 |
37 | positive regulation of chemokine secretion (GO:0090197) | 3.05526233 |
38 | negative regulation of complement activation (GO:0045916) | 3.05364314 |
39 | protein-lipid complex remodeling (GO:0034368) | 3.03432335 |
40 | macromolecular complex remodeling (GO:0034367) | 3.03432335 |
41 | plasma lipoprotein particle remodeling (GO:0034369) | 3.03432335 |
42 | complement activation, classical pathway (GO:0006958) | 3.01356519 |
43 | cholesterol efflux (GO:0033344) | 3.00519638 |
44 | T cell costimulation (GO:0031295) | 2.98092292 |
45 | regulation of humoral immune response (GO:0002920) | 2.93869511 |
46 | positive regulation of tolerance induction (GO:0002645) | 2.93189108 |
47 | lymphocyte costimulation (GO:0031294) | 2.91569843 |
48 | pinocytosis (GO:0006907) | 2.90680615 |
49 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.90276760 |
50 | plasma lipoprotein particle organization (GO:0071827) | 2.90165988 |
51 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.89945060 |
52 | T cell migration (GO:0072678) | 2.88615693 |
53 | regulation of hypersensitivity (GO:0002883) | 2.87468702 |
54 | positive regulation of phagocytosis (GO:0050766) | 2.86147222 |
55 | regulation of extracellular matrix disassembly (GO:0010715) | 2.85924653 |
56 | protein activation cascade (GO:0072376) | 2.85240694 |
57 | high-density lipoprotein particle remodeling (GO:0034375) | 2.85105623 |
58 | valine metabolic process (GO:0006573) | 2.81815458 |
59 | protein-lipid complex subunit organization (GO:0071825) | 2.81707808 |
60 | microglial cell activation (GO:0001774) | 2.79784039 |
61 | response to interleukin-15 (GO:0070672) | 2.79479932 |
62 | blood coagulation, intrinsic pathway (GO:0007597) | 2.76502036 |
63 | regulation of tolerance induction (GO:0002643) | 2.76232242 |
64 | reverse cholesterol transport (GO:0043691) | 2.74864103 |
65 | complement activation (GO:0006956) | 2.74065514 |
66 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.72568442 |
67 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.70975896 |
68 | positive regulation of blood coagulation (GO:0030194) | 2.70303639 |
69 | positive regulation of hemostasis (GO:1900048) | 2.70303639 |
70 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.69620515 |
71 | regulation of cholesterol esterification (GO:0010872) | 2.69292083 |
72 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.69278815 |
73 | positive regulation of interleukin-2 production (GO:0032743) | 2.68563425 |
74 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.68371545 |
75 | detection of biotic stimulus (GO:0009595) | 2.67617858 |
76 | positive regulation of B cell differentiation (GO:0045579) | 2.67356896 |
77 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.66915225 |
78 | lipoprotein metabolic process (GO:0042157) | 2.66716628 |
79 | negative regulation of humoral immune response (GO:0002921) | 2.66567201 |
80 | alpha-linolenic acid metabolic process (GO:0036109) | 2.66527514 |
81 | nuclear pore complex assembly (GO:0051292) | 2.66169078 |
82 | plasma lipoprotein particle clearance (GO:0034381) | 2.65797674 |
83 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.65611145 |
84 | regulation of chemokine secretion (GO:0090196) | 2.65603009 |
85 | interferon-gamma production (GO:0032609) | 2.65255971 |
86 | interkinetic nuclear migration (GO:0022027) | 2.64901270 |
87 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.64061074 |
88 | negative regulation of fatty acid transport (GO:2000192) | 2.63518826 |
89 | histone H3-K4 trimethylation (GO:0080182) | 2.63292327 |
90 | positive regulation of histone deacetylation (GO:0031065) | 2.61209885 |
91 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.60262229 |
92 | positive regulation of interferon-alpha production (GO:0032727) | 2.59545431 |
93 | regulation of B cell differentiation (GO:0045577) | 2.59199944 |
94 | dicarboxylic acid biosynthetic process (GO:0043650) | 2.58397804 |
95 | germinal center formation (GO:0002467) | 2.57837866 |
96 | * cellular response to ethanol (GO:0071361) | 2.57807033 |
97 | regulation of endothelial cell chemotaxis (GO:2001026) | 2.56533678 |
98 | low-density lipoprotein particle clearance (GO:0034383) | 2.55645039 |
99 | negative regulation of cholesterol transport (GO:0032375) | 2.55320362 |
100 | negative regulation of sterol transport (GO:0032372) | 2.55320362 |
101 | B cell receptor signaling pathway (GO:0050853) | 2.55230748 |
102 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.52392097 |
103 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.51887295 |
104 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.51751310 |
105 | T-helper cell differentiation (GO:0042093) | 2.51751310 |
106 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.51512456 |
107 | positive regulation of coagulation (GO:0050820) | 2.51111430 |
108 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.50435943 |
109 | embryonic process involved in female pregnancy (GO:0060136) | 2.50361081 |
110 | cellular response to interleukin-15 (GO:0071350) | 2.49017949 |
111 | phospholipid homeostasis (GO:0055091) | 2.48497097 |
112 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.47951063 |
113 | Rap protein signal transduction (GO:0032486) | 2.47644721 |
114 | detection of other organism (GO:0098543) | 2.46598892 |
115 | heterotypic cell-cell adhesion (GO:0034113) | 2.45691290 |
116 | macrophage activation (GO:0042116) | 2.45338250 |
117 | B cell homeostasis (GO:0001782) | 2.44180474 |
118 | regulation of phagocytosis (GO:0050764) | 2.43066855 |
119 | iron ion import (GO:0097286) | 2.42592637 |
120 | response to muramyl dipeptide (GO:0032495) | 2.41394258 |
121 | mannose metabolic process (GO:0006013) | 2.40673819 |
122 | growth hormone receptor signaling pathway (GO:0060396) | 2.39987889 |
123 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 2.39568151 |
124 | regulation of alkaline phosphatase activity (GO:0010692) | 2.38935322 |
125 | alpha-beta T cell differentiation (GO:0046632) | 2.38770960 |
126 | hepatocyte apoptotic process (GO:0097284) | 2.38370712 |
127 | positive regulation of granulocyte differentiation (GO:0030854) | 2.38024543 |
128 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.37309614 |
129 | regulation of interferon-alpha production (GO:0032647) | 2.36484638 |
130 | regulation of establishment of cell polarity (GO:2000114) | 2.36098937 |
131 | negative regulation of T cell apoptotic process (GO:0070233) | 2.35739757 |
132 | regulation of cholesterol homeostasis (GO:2000188) | 2.35715680 |
133 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.34586836 |
134 | response to host immune response (GO:0052572) | 2.34156818 |
135 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.34156818 |
136 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.32753479 |
137 | alpha-beta T cell activation (GO:0046631) | 2.32131109 |
138 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.32117733 |
139 | positive regulation of fatty acid oxidation (GO:0046321) | 2.31608187 |
140 | acetyl-CoA metabolic process (GO:0006084) | 2.29951625 |
141 | regulation of triglyceride catabolic process (GO:0010896) | 2.28502869 |
142 | plasma lipoprotein particle assembly (GO:0034377) | 2.27522512 |
143 | positive regulation of humoral immune response (GO:0002922) | 2.26075257 |
144 | regulation of sequestering of triglyceride (GO:0010889) | 2.25874362 |
145 | regulation of regulatory T cell differentiation (GO:0045589) | 2.24902420 |
146 | very-low-density lipoprotein particle assembly (GO:0034379) | 2.22345172 |
147 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.22047293 |
148 | protein-lipid complex assembly (GO:0065005) | 2.21216360 |
149 | response to laminar fluid shear stress (GO:0034616) | 2.21197555 |
150 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.21151354 |
151 | T cell proliferation (GO:0042098) | 2.19085675 |
152 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 2.16937942 |
153 | phospholipid efflux (GO:0033700) | 2.16837463 |
154 | complement activation, alternative pathway (GO:0006957) | 2.13594652 |
155 | response to lipoprotein particle (GO:0055094) | 2.13172268 |
156 | modulation by symbiont of host immune response (GO:0052553) | 2.13128379 |
157 | positive regulation by symbiont of host defense response (GO:0052509) | 2.13128379 |
158 | modulation by symbiont of host defense response (GO:0052031) | 2.13128379 |
159 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.13128379 |
160 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.13128379 |
161 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.13128379 |
162 | urea cycle (GO:0000050) | 2.12827030 |
163 | urea metabolic process (GO:0019627) | 2.12827030 |
164 | transcytosis (GO:0045056) | 2.12616723 |
165 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.11734941 |
166 | regulation of B cell proliferation (GO:0030888) | 2.11535704 |
167 | negative regulation of bone resorption (GO:0045779) | 2.10974806 |
168 | lymphocyte homeostasis (GO:0002260) | 2.10614329 |
169 | positive regulation of cholesterol efflux (GO:0010875) | 2.10530711 |
170 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.09813813 |
171 | T cell differentiation (GO:0030217) | 2.09734808 |
172 | fatty acid beta-oxidation (GO:0006635) | 2.09232218 |
173 | glyoxylate metabolic process (GO:0046487) | 2.08617593 |
174 | positive regulation of sterol transport (GO:0032373) | 2.08476345 |
175 | positive regulation of cholesterol transport (GO:0032376) | 2.08476345 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.03998984 |
2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.12761621 |
3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.36086693 |
4 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.24460225 |
5 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.12146009 |
6 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.78294227 |
7 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.48678785 |
8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.47871731 |
9 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.47322684 |
10 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.45704774 |
11 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.36855134 |
12 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.35166552 |
13 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.27672371 |
14 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.20967817 |
15 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.12231016 |
16 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.05058040 |
17 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.04775608 |
18 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.03561018 |
19 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.94446988 |
20 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.89999249 |
21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.89612027 |
22 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.83436158 |
23 | * Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.81709580 |
24 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.81372311 |
25 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.77980412 |
26 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.72898152 |
27 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.71282028 |
28 | MYB_26560356_Chip-Seq_TH2_Human | 1.66451112 |
29 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.62983501 |
30 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.62739816 |
31 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.59680365 |
32 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.53622055 |
33 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.48854187 |
34 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.48308685 |
35 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.42995789 |
36 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.41633062 |
37 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.39156121 |
38 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.38741393 |
39 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.38646524 |
40 | * MAF_26560356_Chip-Seq_TH1_Human | 1.35308314 |
41 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.33459395 |
42 | * MYB_26560356_Chip-Seq_TH1_Human | 1.33257167 |
43 | GATA1_22025678_ChIP-Seq_K562_Human | 1.32528861 |
44 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.32183918 |
45 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.31213121 |
46 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.30471203 |
47 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.28757144 |
48 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.28248380 |
49 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.27980074 |
50 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.24168874 |
51 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.23447302 |
52 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.23326158 |
53 | * AR_21572438_ChIP-Seq_LNCaP_Human | 1.23311976 |
54 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.22866270 |
55 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.22850434 |
56 | MYC_22102868_ChIP-Seq_BL_Human | 1.20177008 |
57 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.19704340 |
58 | UTX_26944678_Chip-Seq_JUKART_Human | 1.19407904 |
59 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.19286213 |
60 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.19101413 |
61 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.18729564 |
62 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.16214890 |
63 | * SPI1_23127762_ChIP-Seq_K562_Human | 1.15320303 |
64 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.14711599 |
65 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.13257659 |
66 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.12815251 |
67 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.12726467 |
68 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.12698780 |
69 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.12193892 |
70 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.11382308 |
71 | * FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.11302252 |
72 | * CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.09503987 |
73 | GATA2_19941826_ChIP-Seq_K562_Human | 1.09212183 |
74 | * SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09161316 |
75 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.07030612 |
76 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.06438845 |
77 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.06248025 |
78 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.04627126 |
79 | GATA1_19941826_ChIP-Seq_K562_Human | 1.03110921 |
80 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.03071464 |
81 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.02702158 |
82 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.00731205 |
83 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.00529475 |
84 | * CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.98018924 |
85 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.97780135 |
86 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.97020633 |
87 | * NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.96458065 |
88 | TP53_16413492_ChIP-PET_HCT116_Human | 0.96338769 |
89 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.95636506 |
90 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.95636506 |
91 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.95241985 |
92 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.95095693 |
93 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.94438622 |
94 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.93064068 |
95 | * NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.91038086 |
96 | * NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.91038086 |
97 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.90993249 |
98 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.90993249 |
99 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.90817170 |
100 | RXR_22108803_ChIP-Seq_LS180_Human | 0.90721514 |
101 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.90692243 |
102 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90067599 |
103 | * SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.89989905 |
104 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.88891526 |
105 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.88851638 |
106 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.88680708 |
107 | * CJUN_26792858_Chip-Seq_BT549_Human | 0.88054869 |
108 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.87711929 |
109 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.86788016 |
110 | * PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.86429752 |
111 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84766683 |
112 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.84057867 |
113 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.83776259 |
114 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.83698737 |
115 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.83568504 |
116 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.83196978 |
117 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.81917824 |
118 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.80533600 |
119 | * SMRT_27268052_Chip-Seq_Bcells_Human | 0.79742886 |
120 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.79358486 |
121 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 0.78664056 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003763_abnormal_thymus_physiology | 3.08191436 |
2 | MP0000569_abnormal_digit_pigmentation | 2.88134779 |
3 | MP0008057_abnormal_DNA_replication | 2.86182049 |
4 | MP0005360_urolithiasis | 2.81516899 |
5 | MP0003300_gastrointestinal_ulcer | 2.53607269 |
6 | MP0005365_abnormal_bile_salt | 2.52378993 |
7 | MP0001835_abnormal_antigen_presentation | 2.49535346 |
8 | MP0002139_abnormal_hepatobiliary_system | 2.47758450 |
9 | MP0000685_abnormal_immune_system | 2.46578222 |
10 | MP0001800_abnormal_humoral_immune | 2.45380031 |
11 | MP0005387_immune_system_phenotype | 2.45182478 |
12 | MP0001790_abnormal_immune_system | 2.45182478 |
13 | MP0005671_abnormal_response_to | 2.42912795 |
14 | MP0003195_calcinosis | 2.42057968 |
15 | MP0002166_altered_tumor_susceptibility | 2.28980410 |
16 | MP0003191_abnormal_cellular_cholesterol | 2.16180180 |
17 | MP0003724_increased_susceptibility_to | 2.08417549 |
18 | MP0003252_abnormal_bile_duct | 2.07727836 |
19 | MP0005000_abnormal_immune_tolerance | 2.04789899 |
20 | MP0004947_skin_inflammation | 1.96720077 |
21 | MP0005085_abnormal_gallbladder_physiolo | 1.95831346 |
22 | MP0002452_abnormal_antigen_presenting | 1.95556138 |
23 | MP0005670_abnormal_white_adipose | 1.93943367 |
24 | MP0002723_abnormal_immune_serum | 1.92277152 |
25 | MP0010352_gastrointestinal_tract_polyps | 1.89386841 |
26 | MP0003690_abnormal_glial_cell | 1.83646449 |
27 | MP0001873_stomach_inflammation | 1.82383911 |
28 | MP0004185_abnormal_adipocyte_glucose | 1.80759270 |
29 | MP0002420_abnormal_adaptive_immunity | 1.79938689 |
30 | MP0001819_abnormal_immune_cell | 1.76239269 |
31 | MP0006082_CNS_inflammation | 1.74245183 |
32 | MP0001915_intracranial_hemorrhage | 1.73159721 |
33 | MP0002006_tumorigenesis | 1.73079120 |
34 | MP0002419_abnormal_innate_immunity | 1.69289233 |
35 | MP0004381_abnormal_hair_follicle | 1.68113004 |
36 | MP0010155_abnormal_intestine_physiology | 1.56988528 |
37 | MP0009278_abnormal_bone_marrow | 1.56241167 |
38 | MP0005025_abnormal_response_to | 1.55510223 |
39 | MP0003436_decreased_susceptibility_to | 1.55492474 |
40 | MP0002009_preneoplasia | 1.55359051 |
41 | MP0004883_abnormal_blood_vessel | 1.55153223 |
42 | MP0005666_abnormal_adipose_tissue | 1.53665862 |
43 | MP0005076_abnormal_cell_differentiation | 1.53499853 |
44 | MP0005167_abnormal_blood-brain_barrier | 1.53165211 |
45 | MP0002398_abnormal_bone_marrow | 1.52086625 |
46 | MP0000716_abnormal_immune_system | 1.51281403 |
47 | MP0002405_respiratory_system_inflammati | 1.49696742 |
48 | MP0003303_peritoneal_inflammation | 1.48835176 |
49 | MP0004130_abnormal_muscle_cell | 1.48614680 |
50 | MP0009785_altered_susceptibility_to | 1.44711666 |
51 | MP0002933_joint_inflammation | 1.44035795 |
52 | MP0002254_reproductive_system_inflammat | 1.42728823 |
53 | MP0005451_abnormal_body_composition | 1.42400776 |
54 | MP0005058_abnormal_lysosome_morphology | 1.41956195 |
55 | MP0000609_abnormal_liver_physiology | 1.41807779 |
56 | MP0010329_abnormal_lipoprotein_level | 1.41617655 |
57 | MP0003828_pulmonary_edema | 1.39939418 |
58 | MP0002396_abnormal_hematopoietic_system | 1.39904007 |
59 | MP0001853_heart_inflammation | 1.39705346 |
60 | MP0000465_gastrointestinal_hemorrhage | 1.38135785 |
61 | MP0004510_myositis | 1.36920190 |
62 | MP0002148_abnormal_hypersensitivity_rea | 1.36348404 |
63 | MP0000703_abnormal_thymus_morphology | 1.34662722 |
64 | MP0000689_abnormal_spleen_morphology | 1.33728830 |
65 | MP0000920_abnormal_myelination | 1.32492172 |
66 | MP0000604_amyloidosis | 1.31915908 |
67 | MP0005464_abnormal_platelet_physiology | 1.31869148 |
68 | MP0000383_abnormal_hair_follicle | 1.31546090 |
69 | MP0003656_abnormal_erythrocyte_physiolo | 1.31476473 |
70 | MP0003453_abnormal_keratinocyte_physiol | 1.30224163 |
71 | MP0003045_fibrosis | 1.29139377 |
72 | MP0001845_abnormal_inflammatory_respons | 1.29065905 |
73 | MP0002138_abnormal_hepatobiliary_system | 1.29005417 |
74 | MP0009384_cardiac_valve_regurgitation | 1.28054361 |
75 | MP0009764_decreased_sensitivity_to | 1.27791209 |
76 | MP0002722_abnormal_immune_system | 1.25378154 |
77 | MP0003183_abnormal_peptide_metabolism | 1.22395408 |
78 | MP0001851_eye_inflammation | 1.22197049 |
79 | MP0010678_abnormal_skin_adnexa | 1.22102605 |
80 | MP0005164_abnormal_response_to | 1.21784810 |
81 | MP0002998_abnormal_bone_remodeling | 1.19808133 |
82 | MP0008875_abnormal_xenobiotic_pharmacok | 1.18836952 |
83 | MP0002168_other_aberrant_phenotype | 1.16702335 |
84 | MP0010368_abnormal_lymphatic_system | 1.16124280 |
85 | MP0009115_abnormal_fat_cell | 1.15944784 |
86 | MP0002118_abnormal_lipid_homeostasis | 1.13707116 |
87 | MP0008004_abnormal_stomach_pH | 1.12810243 |
88 | MP0003172_abnormal_lysosome_physiology | 1.10666420 |
89 | MP0008260_abnormal_autophagy | 1.09794596 |
90 | MP0008469_abnormal_protein_level | 1.09527377 |
91 | MP0002429_abnormal_blood_cell | 1.09385607 |
92 | MP0009333_abnormal_splenocyte_physiolog | 1.08623036 |
93 | MP0002971_abnormal_brown_adipose | 1.06870929 |
94 | MP0000371_diluted_coat_color | 1.06358196 |
95 | MP0001533_abnormal_skeleton_physiology | 1.06255158 |
96 | MP0003705_abnormal_hypodermis_morpholog | 1.05470153 |
97 | MP0005375_adipose_tissue_phenotype | 1.04786645 |
98 | MP0005408_hypopigmentation | 1.04610920 |
99 | MP0009840_abnormal_foam_cell | 1.01260181 |
100 | MP0006054_spinal_hemorrhage | 1.00465890 |
101 | * MP0001666_abnormal_nutrient_absorption | 0.99636318 |
102 | MP0005409_darkened_coat_color | 0.98335063 |
103 | MP0009763_increased_sensitivity_to | 0.96983660 |
104 | MP0009765_abnormal_xenobiotic_induced | 0.91889434 |
105 | MP0004264_abnormal_extraembryonic_tissu | 0.91356106 |
106 | MP0003091_abnormal_cell_migration | 0.91008014 |
107 | MP0002060_abnormal_skin_morphology | 0.89727289 |
108 | MP0003950_abnormal_plasma_membrane | 0.89279060 |
109 | MP0002877_abnormal_melanocyte_morpholog | 0.87964776 |
110 | MP0010307_abnormal_tumor_latency | 0.87853213 |
111 | MP0000767_abnormal_smooth_muscle | 0.85855715 |
112 | MP0000249_abnormal_blood_vessel | 0.85324521 |
113 | MP0008438_abnormal_cutaneous_collagen | 0.84641758 |
114 | MP0000858_altered_metastatic_potential | 0.84346985 |
115 | MP0004808_abnormal_hematopoietic_stem | 0.83462288 |
116 | MP0005334_abnormal_fat_pad | 0.82692482 |
117 | MP0003566_abnormal_cell_adhesion | 0.82344530 |
118 | MP0005621_abnormal_cell_physiology | 0.81616027 |
119 | MP0001661_extended_life_span | 0.80622191 |
120 | MP0002136_abnormal_kidney_physiology | 0.79523048 |
121 | MP0005023_abnormal_wound_healing | 0.78577632 |
122 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.76731111 |
123 | MP0009643_abnormal_urine_homeostasis | 0.75965635 |
124 | MP0001545_abnormal_hematopoietic_system | 0.75819245 |
125 | MP0005397_hematopoietic_system_phenotyp | 0.75819245 |
126 | MP0002928_abnormal_bile_duct | 0.75581692 |
127 | * MP0003868_abnormal_feces_composition | 0.75442372 |
128 | MP0001216_abnormal_epidermal_layer | 0.75054778 |
Rank | Gene Set | Z-score |
---|---|---|
1 | T lymphocytopenia (HP:0005403) | 4.55897620 |
2 | Abnormality of T cell number (HP:0011839) | 4.38543781 |
3 | Thyroiditis (HP:0100646) | 4.03679179 |
4 | Severe combined immunodeficiency (HP:0004430) | 3.90444734 |
5 | Eosinophilia (HP:0001880) | 3.88232937 |
6 | Combined immunodeficiency (HP:0005387) | 3.60587718 |
7 | Recurrent viral infections (HP:0004429) | 3.55818270 |
8 | Abnormality of the fingertips (HP:0001211) | 3.50315343 |
9 | Abnormality of eosinophils (HP:0001879) | 3.34749064 |
10 | Hypoplasia of the thymus (HP:0000778) | 3.33529807 |
11 | Deep venous thrombosis (HP:0002625) | 3.31645792 |
12 | Panhypogammaglobulinemia (HP:0003139) | 3.29312612 |
13 | Abnormality of B cell number (HP:0010975) | 3.25547731 |
14 | B lymphocytopenia (HP:0010976) | 3.25547731 |
15 | Recurrent fungal infections (HP:0002841) | 3.23171679 |
16 | Granulocytopenia (HP:0001913) | 3.09330185 |
17 | Thick nail (HP:0001805) | 3.07845309 |
18 | Myocardial infarction (HP:0001658) | 3.07787509 |
19 | Colitis (HP:0002583) | 2.91475092 |
20 | Autoimmune thrombocytopenia (HP:0001973) | 2.85135149 |
21 | Nephritis (HP:0000123) | 2.80989861 |
22 | Leukocytosis (HP:0001974) | 2.80282294 |
23 | Complement deficiency (HP:0004431) | 2.79954363 |
24 | Hemorrhage of the eye (HP:0011885) | 2.79067064 |
25 | Hypobetalipoproteinemia (HP:0003563) | 2.76929422 |
26 | Premature skin wrinkling (HP:0100678) | 2.75470647 |
27 | Agammaglobulinemia (HP:0004432) | 2.69557222 |
28 | Gastrointestinal stroma tumor (HP:0100723) | 2.69396478 |
29 | Papillary thyroid carcinoma (HP:0002895) | 2.69068984 |
30 | Eczematoid dermatitis (HP:0000976) | 2.65790336 |
31 | Menorrhagia (HP:0000132) | 2.62007292 |
32 | Aortic aneurysm (HP:0004942) | 2.59252205 |
33 | Chronic otitis media (HP:0000389) | 2.57803214 |
34 | Viral hepatitis (HP:0006562) | 2.57242903 |
35 | Mitral stenosis (HP:0001718) | 2.56208460 |
36 | Abnormality of T cells (HP:0002843) | 2.55679363 |
37 | Papilloma (HP:0012740) | 2.53436659 |
38 | Verrucae (HP:0200043) | 2.53436659 |
39 | Chronic diarrhea (HP:0002028) | 2.51517159 |
40 | Inflammation of the large intestine (HP:0002037) | 2.51417258 |
41 | Gingival bleeding (HP:0000225) | 2.50519943 |
42 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.50147680 |
43 | Hyperlipoproteinemia (HP:0010980) | 2.49546274 |
44 | Small epiphyses (HP:0010585) | 2.49512182 |
45 | Conjunctival telangiectasia (HP:0000524) | 2.48750102 |
46 | Spontaneous hematomas (HP:0007420) | 2.45429506 |
47 | Joint hemorrhage (HP:0005261) | 2.44280059 |
48 | Autoimmune hemolytic anemia (HP:0001890) | 2.41892428 |
49 | Xanthomatosis (HP:0000991) | 2.38846261 |
50 | IgM deficiency (HP:0002850) | 2.36703553 |
51 | Gingivitis (HP:0000230) | 2.35739843 |
52 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.34871733 |
53 | Mediastinal lymphadenopathy (HP:0100721) | 2.33156157 |
54 | Spontaneous abortion (HP:0005268) | 2.32288447 |
55 | Scanning speech (HP:0002168) | 2.32105099 |
56 | Vasculitis (HP:0002633) | 2.31767602 |
57 | Stomatitis (HP:0010280) | 2.30941152 |
58 | Subacute progressive viral hepatitis (HP:0006572) | 2.30580840 |
59 | Hematochezia (HP:0002573) | 2.29208448 |
60 | Systemic lupus erythematosus (HP:0002725) | 2.28630818 |
61 | Gastrointestinal inflammation (HP:0004386) | 2.27159780 |
62 | Pustule (HP:0200039) | 2.26385438 |
63 | Prolonged partial thromboplastin time (HP:0003645) | 2.25213921 |
64 | Meningitis (HP:0001287) | 2.24456103 |
65 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.22460372 |
66 | Recurrent cutaneous fungal infections (HP:0011370) | 2.22460372 |
67 | Recurrent skin infections (HP:0001581) | 2.20830249 |
68 | IgA deficiency (HP:0002720) | 2.20460152 |
69 | Lymphopenia (HP:0001888) | 2.20021296 |
70 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.18619910 |
71 | Arterial tortuosity (HP:0005116) | 2.18497809 |
72 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.16735472 |
73 | Recurrent bronchitis (HP:0002837) | 2.16685767 |
74 | Pulmonary embolism (HP:0002204) | 2.16678686 |
75 | Intrahepatic cholestasis (HP:0001406) | 2.16233765 |
76 | Submucous cleft hard palate (HP:0000176) | 2.14058094 |
77 | Cerebral aneurysm (HP:0004944) | 2.13051334 |
78 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.12431970 |
79 | Thrombophlebitis (HP:0004418) | 2.12201421 |
80 | Flat acetabular roof (HP:0003180) | 2.12079340 |
81 | Esophageal varix (HP:0002040) | 2.11785436 |
82 | IgG deficiency (HP:0004315) | 2.11217914 |
83 | Recurrent bacterial skin infections (HP:0005406) | 2.09979877 |
84 | Epiphyseal dysplasia (HP:0002656) | 2.09895510 |
85 | Acanthocytosis (HP:0001927) | 2.08530729 |
86 | Depressed nasal tip (HP:0000437) | 2.05713245 |
87 | Optic neuritis (HP:0100653) | 2.04481130 |
88 | Retrobulbar optic neuritis (HP:0100654) | 2.04481130 |
89 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.03095250 |
90 | Fair hair (HP:0002286) | 2.02492264 |
91 | Cellulitis (HP:0100658) | 2.02297116 |
92 | Acute myeloid leukemia (HP:0004808) | 2.01510974 |
93 | Recurrent abscess formation (HP:0002722) | 2.00267035 |
94 | Narrow palate (HP:0000189) | 1.97653569 |
95 | Abnormality of the common coagulation pathway (HP:0010990) | 1.96017597 |
96 | Hypoalphalipoproteinemia (HP:0003233) | 1.94460186 |
97 | Emphysema (HP:0002097) | 1.92391097 |
98 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.91672427 |
99 | Impaired platelet aggregation (HP:0003540) | 1.91448764 |
100 | Abnormal platelet function (HP:0011869) | 1.91448764 |
101 | Vascular tortuosity (HP:0004948) | 1.91390883 |
102 | Orchitis (HP:0100796) | 1.91074466 |
103 | Abnormality of complement system (HP:0005339) | 1.90755282 |
104 | Abnormal platelet volume (HP:0011876) | 1.89475534 |
105 | Glomerulonephritis (HP:0000099) | 1.89254527 |
106 | Abnormality of the peritoneum (HP:0002585) | 1.89131164 |
107 | Myositis (HP:0100614) | 1.86520973 |
108 | Hepatitis (HP:0012115) | 1.85961569 |
109 | Conjugated hyperbilirubinemia (HP:0002908) | 1.85719291 |
110 | Purpura (HP:0000979) | 1.84742883 |
111 | Disproportionate tall stature (HP:0001519) | 1.84548160 |
112 | Pulmonary infiltrates (HP:0002113) | 1.82895567 |
113 | Hypolipoproteinemia (HP:0010981) | 1.82823157 |
114 | Dysmetric saccades (HP:0000641) | 1.81547744 |
115 | Osteomyelitis (HP:0002754) | 1.80082904 |
116 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.79445568 |
117 | Prolonged bleeding time (HP:0003010) | 1.77815597 |
118 | Epidermoid cyst (HP:0200040) | 1.77602948 |
119 | Aortic dissection (HP:0002647) | 1.77585582 |
120 | Recurrent sinusitis (HP:0011108) | 1.76903403 |
121 | Arterial thrombosis (HP:0004420) | 1.76782021 |
122 | Abnormality of the axillary hair (HP:0100134) | 1.76766482 |
123 | Abnormality of secondary sexual hair (HP:0009888) | 1.76766482 |
124 | Periodontitis (HP:0000704) | 1.76093743 |
125 | Renal cortical cysts (HP:0000803) | 1.74660244 |
126 | Osteolytic defects of the hand bones (HP:0009699) | 1.74185959 |
127 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.74185959 |
128 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.73823902 |
129 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 1.73592189 |
130 | Coarse hair (HP:0002208) | 1.72650495 |
131 | Dislocated radial head (HP:0003083) | 1.72511320 |
132 | Spondylolisthesis (HP:0003302) | 1.72156156 |
133 | Epistaxis (HP:0000421) | 1.69656461 |
134 | Increased mean platelet volume (HP:0011877) | 1.69437021 |
135 | Asymmetry of the thorax (HP:0001555) | 1.69325828 |
136 | Hydroxyprolinuria (HP:0003080) | 1.69238045 |
137 | Abnormality of proline metabolism (HP:0010907) | 1.69238045 |
138 | Hyperglycinuria (HP:0003108) | 1.69228160 |
139 | Hypercholesterolemia (HP:0003124) | 1.68932328 |
140 | Increased IgE level (HP:0003212) | 1.68469768 |
141 | Vascular calcification (HP:0004934) | 1.68262214 |
142 | Cardiovascular calcification (HP:0011915) | 1.68021936 |
143 | Abnormal foot bone ossification (HP:0010675) | 1.67740462 |
144 | Gastrointestinal infarctions (HP:0005244) | 1.66951445 |
145 | Abnormal glucose tolerance (HP:0001952) | 1.66394886 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 3.29022514 |
2 | TXK | 3.11567417 |
3 | BLK | 2.89947207 |
4 | SIK1 | 2.59021649 |
5 | EPHB1 | 2.38869370 |
6 | FGFR4 | 2.38694128 |
7 | TYK2 | 2.15416904 |
8 | JAK1 | 2.15148182 |
9 | ITK | 1.99477343 |
10 | TGFBR2 | 1.99148642 |
11 | TAOK3 | 1.97080961 |
12 | JAK3 | 1.96570460 |
13 | STK10 | 1.96377616 |
14 | AKT3 | 1.94332411 |
15 | IKBKE | 1.88370045 |
16 | FGFR3 | 1.84996395 |
17 | NLK | 1.80900905 |
18 | TNIK | 1.80338587 |
19 | IRAK4 | 1.77962203 |
20 | CSK | 1.77353190 |
21 | MAP3K14 | 1.76240009 |
22 | FGFR2 | 1.76190631 |
23 | TYRO3 | 1.72198155 |
24 | PDGFRB | 1.64684739 |
25 | FES | 1.60021886 |
26 | SGK2 | 1.57881427 |
27 | PKN2 | 1.50811318 |
28 | CDC42BPA | 1.47488175 |
29 | CAMK1D | 1.46964080 |
30 | PIK3CG | 1.45349908 |
31 | PRPF4B | 1.44460118 |
32 | CSF1R | 1.44395740 |
33 | LATS1 | 1.38120992 |
34 | TBK1 | 1.37043629 |
35 | CAMK1G | 1.35573616 |
36 | PRKCQ | 1.33769233 |
37 | ZAP70 | 1.28819332 |
38 | MAP3K10 | 1.27635082 |
39 | LCK | 1.27413031 |
40 | NUAK1 | 1.24137326 |
41 | HCK | 1.22144948 |
42 | WNK1 | 1.19428725 |
43 | MAP3K13 | 1.19259821 |
44 | IRAK3 | 1.17082517 |
45 | IRAK1 | 1.15463392 |
46 | PKN1 | 1.15004834 |
47 | BRD4 | 1.14766166 |
48 | MST4 | 1.13563547 |
49 | GRK6 | 1.12334947 |
50 | ACVR1B | 1.10674354 |
51 | ERN1 | 1.10650302 |
52 | IKBKB | 1.10634718 |
53 | MAP2K3 | 1.08836679 |
54 | MAP3K2 | 1.07487108 |
55 | EEF2K | 1.06046395 |
56 | MAPK7 | 1.04568438 |
57 | JAK2 | 1.03963493 |
58 | PTK6 | 1.03949114 |
59 | BTK | 1.00016970 |
60 | MAP3K7 | 0.97590131 |
61 | TRIB3 | 0.97565274 |
62 | CDK9 | 0.96291164 |
63 | STK24 | 0.95273246 |
64 | RIPK1 | 0.94190688 |
65 | SYK | 0.93647818 |
66 | IRAK2 | 0.91876583 |
67 | STK39 | 0.91105732 |
68 | CLK1 | 0.91089718 |
69 | MARK3 | 0.90203756 |
70 | INSRR | 0.85998624 |
71 | FRK | 0.85692894 |
72 | SGK223 | 0.85348043 |
73 | SGK494 | 0.85348043 |
74 | MAPK12 | 0.85140875 |
75 | TEC | 0.83862076 |
76 | SCYL2 | 0.83128602 |
77 | PRKAA2 | 0.82839941 |
78 | LRRK2 | 0.82226707 |
79 | CDK12 | 0.82181856 |
80 | CHUK | 0.81252743 |
81 | PRKCH | 0.79659272 |
82 | MAP3K6 | 0.79424562 |
83 | DMPK | 0.78970850 |
84 | MELK | 0.78479776 |
85 | LYN | 0.77385578 |
86 | STK4 | 0.74254288 |
87 | BMPR2 | 0.73468034 |
88 | SGK1 | 0.72862961 |
89 | MTOR | 0.72135803 |
90 | KIT | 0.72049014 |
91 | SIK2 | 0.69571830 |
92 | CDK4 | 0.69479884 |
93 | STK3 | 0.67884174 |
94 | RIPK4 | 0.66619620 |
95 | EIF2AK3 | 0.66351078 |
96 | EPHA3 | 0.66220861 |
97 | INSR | 0.64677469 |
98 | SGK3 | 0.63637724 |
99 | MAP3K1 | 0.61211221 |
100 | PDK1 | 0.61013998 |
101 | ICK | 0.60383762 |
102 | NEK9 | 0.58153143 |
103 | PIK3CA | 0.57946513 |
104 | MARK2 | 0.57871947 |
105 | FER | 0.57630964 |
106 | TTN | 0.57007186 |
107 | IGF1R | 0.56797639 |
108 | PIM1 | 0.56397155 |
109 | MAPK11 | 0.56129890 |
110 | NEK6 | 0.55683426 |
111 | PRKD2 | 0.55477590 |
112 | ERBB2 | 0.54944751 |
113 | FGR | 0.54713258 |
114 | PRKD1 | 0.54607313 |
115 | TRPM7 | 0.53758226 |
116 | RET | 0.53667549 |
117 | RPS6KB2 | 0.52501283 |
118 | CDK6 | 0.51875841 |
119 | PDGFRA | 0.51707718 |
120 | MATK | 0.49551624 |
121 | ABL1 | 0.49106208 |
122 | FYN | 0.46395865 |
123 | FGFR1 | 0.45304046 |
124 | MAPK15 | 0.45258354 |
125 | SMG1 | 0.44365310 |
126 | EGFR | 0.44245148 |
127 | PDPK1 | 0.42335193 |
128 | DDR2 | 0.41474164 |
129 | HIPK2 | 0.40566457 |
130 | CAMK4 | 0.39801070 |
131 | TIE1 | 0.39249226 |
132 | YES1 | 0.38963928 |
133 | RPS6KB1 | 0.37973779 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.35786589 |
2 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.28407175 |
3 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.25610883 |
4 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.07142919 |
5 | Fatty acid metabolism_Homo sapiens_hsa01212 | 2.02326121 |
6 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.93607221 |
7 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.87783813 |
8 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.73332831 |
9 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.72233360 |
10 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.70489775 |
11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.68981801 |
12 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.66956545 |
13 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.65133945 |
14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.64554608 |
15 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.63365566 |
16 | Lysine degradation_Homo sapiens_hsa00310 | 1.63227845 |
17 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.55851796 |
18 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.52802104 |
19 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.52326918 |
20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.45589447 |
21 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.45361121 |
22 | Measles_Homo sapiens_hsa05162 | 1.44917992 |
23 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.43119280 |
24 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.39193450 |
25 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.37306601 |
26 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.31560927 |
27 | ABC transporters_Homo sapiens_hsa02010 | 1.21235706 |
28 | Viral myocarditis_Homo sapiens_hsa05416 | 1.21049897 |
29 | Peroxisome_Homo sapiens_hsa04146 | 1.15591742 |
30 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.15257768 |
31 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.14113602 |
32 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.11924171 |
33 | Other glycan degradation_Homo sapiens_hsa00511 | 1.11440876 |
34 | Insulin resistance_Homo sapiens_hsa04931 | 1.11378130 |
35 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.10385326 |
36 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.10128522 |
37 | Leishmaniasis_Homo sapiens_hsa05140 | 1.09910241 |
38 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.06568179 |
39 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.04640147 |
40 | Pertussis_Homo sapiens_hsa05133 | 1.04151879 |
41 | * Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.00721730 |
42 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.00647609 |
43 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.00569178 |
44 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.99201356 |
45 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.99165930 |
46 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.97627439 |
47 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.97173292 |
48 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.96051936 |
49 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.93627700 |
50 | Malaria_Homo sapiens_hsa05144 | 0.91663720 |
51 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.90833675 |
52 | Asthma_Homo sapiens_hsa05310 | 0.90178460 |
53 | Prion diseases_Homo sapiens_hsa05020 | 0.87899029 |
54 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.87773225 |
55 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.87628886 |
56 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.87162566 |
57 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.84708603 |
58 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.82833660 |
59 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82710775 |
60 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.81555589 |
61 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.80909429 |
62 | Glioma_Homo sapiens_hsa05214 | 0.77172206 |
63 | Hepatitis C_Homo sapiens_hsa05160 | 0.76368220 |
64 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.76223780 |
65 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.75825571 |
66 | Endometrial cancer_Homo sapiens_hsa05213 | 0.75795339 |
67 | * Platelet activation_Homo sapiens_hsa04611 | 0.74829322 |
68 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.74727271 |
69 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.74375408 |
70 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.73857756 |
71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.73675376 |
72 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.72576449 |
73 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.70589349 |
74 | Allograft rejection_Homo sapiens_hsa05330 | 0.70157685 |
75 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.70106518 |
76 | Prostate cancer_Homo sapiens_hsa05215 | 0.69096973 |
77 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.68657319 |
78 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.68618343 |
79 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.68045769 |
80 | Amoebiasis_Homo sapiens_hsa05146 | 0.67429719 |
81 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.67249830 |
82 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.66857620 |
83 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.66190907 |
84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.65813917 |
85 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.65633759 |
86 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.65017252 |
87 | Adherens junction_Homo sapiens_hsa04520 | 0.64584414 |
88 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.64546750 |
89 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.63687574 |
90 | Histidine metabolism_Homo sapiens_hsa00340 | 0.63315182 |
91 | Influenza A_Homo sapiens_hsa05164 | 0.62862063 |
92 | Colorectal cancer_Homo sapiens_hsa05210 | 0.62500477 |
93 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.62390827 |
94 | Focal adhesion_Homo sapiens_hsa04510 | 0.61967303 |
95 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.61036293 |
96 | Bile secretion_Homo sapiens_hsa04976 | 0.59970312 |
97 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.59130487 |
98 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.58559970 |
99 | Hepatitis B_Homo sapiens_hsa05161 | 0.58515214 |
100 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.57478393 |
101 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.57295795 |
102 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.57208973 |
103 | Lysosome_Homo sapiens_hsa04142 | 0.56910720 |
104 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.56744054 |
105 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.55593059 |
106 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55105328 |
107 | Retinol metabolism_Homo sapiens_hsa00830 | 0.54568725 |
108 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.54161643 |
109 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.53915086 |
110 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.52995970 |
111 | Legionellosis_Homo sapiens_hsa05134 | 0.50750246 |
112 | * Apoptosis_Homo sapiens_hsa04210 | 0.50381085 |
113 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.49010809 |
114 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.48983046 |
115 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.48314809 |
116 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.47998567 |
117 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.47716811 |
118 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.46498287 |
119 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.46090213 |
120 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.45947193 |
121 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.45660467 |
122 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.42223103 |
123 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.42176794 |
124 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.41523469 |
125 | Tuberculosis_Homo sapiens_hsa05152 | 0.39998877 |
126 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.39519897 |