

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative thymic T cell selection (GO:0045060) | 8.65963614 |
| 2 | negative T cell selection (GO:0043383) | 8.46648085 |
| 3 | positive thymic T cell selection (GO:0045059) | 7.83508312 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 7.54468713 |
| 5 | regulation of isotype switching to IgG isotypes (GO:0048302) | 7.52582393 |
| 6 | thymic T cell selection (GO:0045061) | 7.39473424 |
| 7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 7.27049237 |
| 8 | regulation of T cell tolerance induction (GO:0002664) | 7.26950157 |
| 9 | leukocyte aggregation (GO:0070486) | 7.13178484 |
| 10 | positive T cell selection (GO:0043368) | 6.73124886 |
| 11 | T cell selection (GO:0045058) | 6.59666861 |
| 12 | tolerance induction (GO:0002507) | 6.52083965 |
| 13 | cellular response to interleukin-15 (GO:0071350) | 6.40117120 |
| 14 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 6.31187644 |
| 15 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 6.27149337 |
| 16 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 6.27149337 |
| 17 | response to interleukin-15 (GO:0070672) | 6.16833910 |
| 18 | lymphocyte costimulation (GO:0031294) | 6.08703767 |
| 19 | T cell costimulation (GO:0031295) | 6.08489615 |
| 20 | T cell receptor signaling pathway (GO:0050852) | 5.97419637 |
| 21 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.97062343 |
| 22 | positive regulation of tolerance induction (GO:0002645) | 5.93785469 |
| 23 | regulation of gamma-delta T cell activation (GO:0046643) | 5.58161205 |
| 24 | T cell migration (GO:0072678) | 5.53272402 |
| 25 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.44942678 |
| 26 | sequestering of actin monomers (GO:0042989) | 5.41986121 |
| 27 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.21329865 |
| 28 | negative regulation of cell killing (GO:0031342) | 5.19953868 |
| 29 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.19953868 |
| 30 | regulation of tolerance induction (GO:0002643) | 5.17102407 |
| 31 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 4.97850056 |
| 32 | antigen receptor-mediated signaling pathway (GO:0050851) | 4.91225287 |
| 33 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.86148245 |
| 34 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 4.83733487 |
| 35 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 4.77187325 |
| 36 | regulation of T cell receptor signaling pathway (GO:0050856) | 4.64630216 |
| 37 | interferon-gamma production (GO:0032609) | 4.49904304 |
| 38 | regulation of regulatory T cell differentiation (GO:0045589) | 4.48886739 |
| 39 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.37953493 |
| 40 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.37935346 |
| 41 | regulation of isotype switching (GO:0045191) | 4.34010835 |
| 42 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 4.24332648 |
| 43 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.21125743 |
| 44 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 4.13007783 |
| 45 | regulation of response to interferon-gamma (GO:0060330) | 4.12093093 |
| 46 | positive regulation of interleukin-2 production (GO:0032743) | 4.07454121 |
| 47 | response to type I interferon (GO:0034340) | 4.02346683 |
| 48 | cellular response to type I interferon (GO:0071357) | 4.01629194 |
| 49 | type I interferon signaling pathway (GO:0060337) | 4.01629194 |
| 50 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.94624820 |
| 51 | positive regulation of humoral immune response (GO:0002922) | 3.88214913 |
| 52 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.87674771 |
| 53 | regulation of B cell mediated immunity (GO:0002712) | 3.80532635 |
| 54 | regulation of immunoglobulin production (GO:0002637) | 3.77911372 |
| 55 | mast cell activation (GO:0045576) | 3.74989538 |
| 56 | regulation of defense response to virus by virus (GO:0050690) | 3.74724958 |
| 57 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.73889347 |
| 58 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.73889347 |
| 59 | positive regulation of lamellipodium assembly (GO:0010592) | 3.73802990 |
| 60 | positive regulation of interleukin-4 production (GO:0032753) | 3.70577060 |
| 61 | regulation of interleukin-4 production (GO:0032673) | 3.64329635 |
| 62 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.63948293 |
| 63 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.63948293 |
| 64 | tumor necrosis factor-mediated signaling pathway (GO:0033209) | 3.62708998 |
| 65 | positive regulation of isotype switching (GO:0045830) | 3.61887231 |
| 66 | negative regulation of B cell mediated immunity (GO:0002713) | 3.57220506 |
| 67 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.57220506 |
| 68 | negative regulation of type 2 immune response (GO:0002829) | 3.52700815 |
| 69 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.52188638 |
| 70 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.49634647 |
| 71 | positive regulation of B cell mediated immunity (GO:0002714) | 3.49634647 |
| 72 | cellular response to interferon-beta (GO:0035458) | 3.46743743 |
| 73 | leukocyte cell-cell adhesion (GO:0007159) | 3.45892820 |
| 74 | negative regulation of T cell mediated immunity (GO:0002710) | 3.44164041 |
| 75 | regulation of respiratory burst (GO:0060263) | 3.41499964 |
| 76 | T cell differentiation (GO:0030217) | 3.41412367 |
| 77 | positive regulation of T cell activation (GO:0050870) | 3.34336574 |
| 78 | immune response-activating cell surface receptor signaling pathway (GO:0002429) | 3.34084447 |
| 79 | NIK/NF-kappaB signaling (GO:0038061) | 3.33473592 |
| 80 | T cell activation (GO:0042110) | 3.26794055 |
| 81 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.26758069 |
| 82 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.26356120 |
| 83 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.23641026 |
| 84 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.19931497 |
| 85 | positive regulation of lamellipodium organization (GO:1902745) | 3.19733130 |
| 86 | T cell homeostasis (GO:0043029) | 3.17554685 |
| 87 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.15493579 |
| 88 | regulation of interleukin-2 production (GO:0032663) | 3.11538294 |
| 89 | regulation of immunoglobulin secretion (GO:0051023) | 3.11391598 |
| 90 | positive regulation of DNA recombination (GO:0045911) | 3.09433377 |
| 91 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.08247377 |
| 92 | positive regulation of T cell differentiation in thymus (GO:0033089) | 3.05811743 |
| 93 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.05018163 |
| 94 | alpha-beta T cell differentiation (GO:0046632) | 3.04396626 |
| 95 | natural killer cell activation (GO:0030101) | 3.03876108 |
| 96 | regulation of T cell activation (GO:0050863) | 3.03749633 |
| 97 | positive regulation of immunoglobulin production (GO:0002639) | 3.02713848 |
| 98 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.97453712 |
| 99 | alpha-beta T cell activation (GO:0046631) | 2.97435127 |
| 100 | positive regulation of macrophage differentiation (GO:0045651) | 2.96823252 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 8.88726667 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 6.12956340 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.83820402 |
| 4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.70902902 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.45356460 |
| 6 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 4.10499907 |
| 7 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.83654502 |
| 8 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.68206605 |
| 9 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 3.41068779 |
| 10 | MYB_26560356_Chip-Seq_TH2_Human | 3.37328142 |
| 11 | MYC_22102868_ChIP-Seq_BL_Human | 3.20009175 |
| 12 | MAF_26560356_Chip-Seq_TH1_Human | 3.06932652 |
| 13 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.01490025 |
| 14 | UTX_26944678_Chip-Seq_JUKART_Human | 2.90474244 |
| 15 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.82686778 |
| 16 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.78022923 |
| 17 | MYB_26560356_Chip-Seq_TH1_Human | 2.75377771 |
| 18 | MAF_26560356_Chip-Seq_TH2_Human | 2.35059292 |
| 19 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.32723204 |
| 20 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.28397490 |
| 21 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.22055665 |
| 22 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.17368825 |
| 23 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.13017990 |
| 24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.09631106 |
| 25 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.00748941 |
| 26 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.90730721 |
| 27 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.87726751 |
| 28 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.87315873 |
| 29 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.84222372 |
| 30 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.80997684 |
| 31 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.80490432 |
| 32 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.72725437 |
| 33 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.68426772 |
| 34 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.61113869 |
| 35 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.53036472 |
| 36 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.51332427 |
| 37 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.46624981 |
| 38 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.46556373 |
| 39 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.40967123 |
| 40 | GATA3_26560356_Chip-Seq_TH2_Human | 1.38471979 |
| 41 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.37719220 |
| 42 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.37472051 |
| 43 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.36329196 |
| 44 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.35968129 |
| 45 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.34952457 |
| 46 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.32454825 |
| 47 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.32234956 |
| 48 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.29659432 |
| 49 | SPI1_23127762_ChIP-Seq_K562_Human | 1.29317988 |
| 50 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.28031552 |
| 51 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.27326597 |
| 52 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.23666674 |
| 53 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.22852700 |
| 54 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19092386 |
| 55 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.18025090 |
| 56 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.17428836 |
| 57 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.17204310 |
| 58 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.16156984 |
| 59 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.14624863 |
| 60 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.14605780 |
| 61 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.07407975 |
| 62 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.07229976 |
| 63 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.06954990 |
| 64 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.04559132 |
| 65 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.01740594 |
| 66 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.97281601 |
| 67 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.96251860 |
| 68 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92541601 |
| 69 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91442987 |
| 70 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.90669779 |
| 71 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.90491770 |
| 72 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90220408 |
| 73 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.88768187 |
| 74 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.88117194 |
| 75 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.87909059 |
| 76 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.85528132 |
| 77 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.84906817 |
| 78 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.84740136 |
| 79 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.84277415 |
| 80 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.83531096 |
| 81 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.82199399 |
| 82 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.78115322 |
| 83 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.76862922 |
| 84 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.74908161 |
| 85 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.74565059 |
| 86 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.73819238 |
| 87 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.73731881 |
| 88 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.73583853 |
| 89 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.71436847 |
| 90 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.70065683 |
| 91 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.69963865 |
| 92 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.68663827 |
| 93 | FLI1_21867929_ChIP-Seq_CD8_Mouse | 0.68122670 |
| 94 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.68027721 |
| 95 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.67697353 |
| 96 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.67116126 |
| 97 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.67005712 |
| 98 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.66915098 |
| 99 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.66130920 |
| 100 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.65533069 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 6.23336902 |
| 2 | MP0005671_abnormal_response_to | 5.19287527 |
| 3 | MP0000685_abnormal_immune_system | 3.74547275 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.72717097 |
| 5 | MP0002166_altered_tumor_susceptibility | 3.62019026 |
| 6 | MP0001800_abnormal_humoral_immune | 3.21276305 |
| 7 | MP0006082_CNS_inflammation | 3.07979782 |
| 8 | MP0002006_tumorigenesis | 3.07942464 |
| 9 | MP0005000_abnormal_immune_tolerance | 3.06347239 |
| 10 | MP0009333_abnormal_splenocyte_physiolog | 3.01839624 |
| 11 | MP0001790_abnormal_immune_system | 2.97302285 |
| 12 | MP0005387_immune_system_phenotype | 2.97302285 |
| 13 | MP0009785_altered_susceptibility_to | 2.91718143 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.89456625 |
| 15 | MP0002723_abnormal_immune_serum | 2.87530712 |
| 16 | MP0002398_abnormal_bone_marrow | 2.86944144 |
| 17 | MP0001819_abnormal_immune_cell | 2.86262326 |
| 18 | MP0003724_increased_susceptibility_to | 2.72421855 |
| 19 | MP0005025_abnormal_response_to | 2.64974740 |
| 20 | MP0000703_abnormal_thymus_morphology | 2.58473302 |
| 21 | MP0002452_abnormal_antigen_presenting | 2.55845587 |
| 22 | MP0002405_respiratory_system_inflammati | 2.50450703 |
| 23 | MP0000716_abnormal_immune_system | 2.50376950 |
| 24 | MP0002933_joint_inflammation | 2.36568041 |
| 25 | MP0002722_abnormal_immune_system | 2.33368679 |
| 26 | MP0004947_skin_inflammation | 2.33275423 |
| 27 | MP0001873_stomach_inflammation | 2.30293807 |
| 28 | MP0003866_abnormal_defecation | 2.26253617 |
| 29 | MP0000689_abnormal_spleen_morphology | 2.25883443 |
| 30 | MP0010155_abnormal_intestine_physiology | 2.16452420 |
| 31 | MP0002396_abnormal_hematopoietic_system | 2.10726506 |
| 32 | MP0002429_abnormal_blood_cell | 1.98576258 |
| 33 | MP0004510_myositis | 1.95893192 |
| 34 | MP0003436_decreased_susceptibility_to | 1.92394579 |
| 35 | MP0005310_abnormal_salivary_gland | 1.87082636 |
| 36 | MP0003300_gastrointestinal_ulcer | 1.76657530 |
| 37 | MP0002419_abnormal_innate_immunity | 1.69891053 |
| 38 | MP0001845_abnormal_inflammatory_respons | 1.65400691 |
| 39 | MP0002148_abnormal_hypersensitivity_rea | 1.62123718 |
| 40 | MP0001853_heart_inflammation | 1.55786232 |
| 41 | MP0000858_altered_metastatic_potential | 1.43489518 |
| 42 | MP0001851_eye_inflammation | 1.41382371 |
| 43 | MP0004381_abnormal_hair_follicle | 1.34443063 |
| 44 | MP0005464_abnormal_platelet_physiology | 1.28880638 |
| 45 | MP0008469_abnormal_protein_level | 1.23316904 |
| 46 | MP0003448_altered_tumor_morphology | 1.16252363 |
| 47 | MP0005451_abnormal_body_composition | 1.14917000 |
| 48 | MP0002019_abnormal_tumor_incidence | 1.08183712 |
| 49 | MP0005023_abnormal_wound_healing | 1.06445522 |
| 50 | MP0001348_abnormal_lacrimal_gland | 1.03353386 |
| 51 | MP0000465_gastrointestinal_hemorrhage | 1.02012400 |
| 52 | MP0000490_abnormal_crypts_of | 0.98424040 |
| 53 | MP0003303_peritoneal_inflammation | 0.96884338 |
| 54 | MP0003077_abnormal_cell_cycle | 0.94899246 |
| 55 | MP0002822_catalepsy | 0.94881468 |
| 56 | MP0001533_abnormal_skeleton_physiology | 0.94174442 |
| 57 | MP0003045_fibrosis | 0.89276583 |
| 58 | MP0004808_abnormal_hematopoietic_stem | 0.88242835 |
| 59 | MP0000604_amyloidosis | 0.87972529 |
| 60 | MP0009763_increased_sensitivity_to | 0.85543726 |
| 61 | MP0002998_abnormal_bone_remodeling | 0.82235439 |
| 62 | MP0003329_amyloid_beta_deposits | 0.81021020 |
| 63 | MP0003787_abnormal_imprinting | 0.78726875 |
| 64 | MP0008057_abnormal_DNA_replication | 0.73566001 |
| 65 | MP0009765_abnormal_xenobiotic_induced | 0.70922015 |
| 66 | MP0002009_preneoplasia | 0.69561060 |
| 67 | MP0009764_decreased_sensitivity_to | 0.69103724 |
| 68 | MP0000477_abnormal_intestine_morphology | 0.68702208 |
| 69 | MP0008877_abnormal_DNA_methylation | 0.68067616 |
| 70 | MP0010352_gastrointestinal_tract_polyps | 0.66730417 |
| 71 | MP0005075_abnormal_melanosome_morpholog | 0.63537236 |
| 72 | MP0003795_abnormal_bone_structure | 0.60607159 |
| 73 | MP0002693_abnormal_pancreas_physiology | 0.59736211 |
| 74 | MP0008569_lethality_at_weaning | 0.56632390 |
| 75 | MP0010234_abnormal_vibrissa_follicle | 0.56624898 |
| 76 | MP0000343_altered_response_to | 0.55637817 |
| 77 | MP0002163_abnormal_gland_morphology | 0.53980183 |
| 78 | MP0010094_abnormal_chromosome_stability | 0.53081651 |
| 79 | MP0003221_abnormal_cardiomyocyte_apopto | 0.51973568 |
| 80 | MP0003453_abnormal_keratinocyte_physiol | 0.51835088 |
| 81 | MP0004957_abnormal_blastocyst_morpholog | 0.49026869 |
| 82 | MP0001216_abnormal_epidermal_layer | 0.48910584 |
| 83 | MP0003693_abnormal_embryo_hatching | 0.48551647 |
| 84 | MP0003111_abnormal_nucleus_morphology | 0.47391695 |
| 85 | MP0000609_abnormal_liver_physiology | 0.47262359 |
| 86 | MP0001191_abnormal_skin_condition | 0.47246327 |
| 87 | MP0002909_abnormal_adrenal_gland | 0.46561952 |
| 88 | MP0005397_hematopoietic_system_phenotyp | 0.46187654 |
| 89 | MP0001545_abnormal_hematopoietic_system | 0.46187654 |
| 90 | MP0002132_abnormal_respiratory_system | 0.45903112 |
| 91 | MP0008872_abnormal_physiological_respon | 0.45669291 |
| 92 | MP0001119_abnormal_female_reproductive | 0.44015928 |
| 93 | MP0001243_abnormal_dermal_layer | 0.43487618 |
| 94 | MP0000313_abnormal_cell_death | 0.43056193 |
| 95 | MP0002138_abnormal_hepatobiliary_system | 0.42808860 |
| 96 | MP0008007_abnormal_cellular_replicative | 0.42313786 |
| 97 | MP0002136_abnormal_kidney_physiology | 0.41308963 |
| 98 | MP0005076_abnormal_cell_differentiation | 0.40924767 |
| 99 | MP0001663_abnormal_digestive_system | 0.39329235 |
| 100 | MP0008961_abnormal_basal_metabolism | 0.35593037 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Severe combined immunodeficiency (HP:0004430) | 6.85493506 |
| 2 | T lymphocytopenia (HP:0005403) | 6.83483997 |
| 3 | Abnormality of T cell number (HP:0011839) | 6.72517033 |
| 4 | Recurrent bronchitis (HP:0002837) | 6.39323147 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.36862680 |
| 6 | Combined immunodeficiency (HP:0005387) | 6.34089064 |
| 7 | IgG deficiency (HP:0004315) | 6.14761310 |
| 8 | Increased IgM level (HP:0003496) | 5.90541150 |
| 9 | Abnormality of T cells (HP:0002843) | 5.72563151 |
| 10 | Stomatitis (HP:0010280) | 5.69482963 |
| 11 | IgM deficiency (HP:0002850) | 5.64249204 |
| 12 | Chronic mucocutaneous candidiasis (HP:0002728) | 5.51427097 |
| 13 | Recurrent cutaneous fungal infections (HP:0011370) | 5.51427097 |
| 14 | Autoimmune hemolytic anemia (HP:0001890) | 5.31630764 |
| 15 | B lymphocytopenia (HP:0010976) | 4.86554375 |
| 16 | Abnormality of B cell number (HP:0010975) | 4.86554375 |
| 17 | Recurrent fungal infections (HP:0002841) | 4.81683123 |
| 18 | Eczematoid dermatitis (HP:0000976) | 4.58736524 |
| 19 | Abnormality of T cell physiology (HP:0011840) | 4.56650951 |
| 20 | Chronic diarrhea (HP:0002028) | 4.32529492 |
| 21 | Lymphopenia (HP:0001888) | 4.27354489 |
| 22 | Panhypogammaglobulinemia (HP:0003139) | 4.27124280 |
| 23 | Chronic otitis media (HP:0000389) | 4.24338635 |
| 24 | Pustule (HP:0200039) | 4.14481893 |
| 25 | IgA deficiency (HP:0002720) | 4.14358144 |
| 26 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 4.13595699 |
| 27 | Abnormality of eosinophils (HP:0001879) | 4.01512577 |
| 28 | Abnormality of the fingertips (HP:0001211) | 3.82816419 |
| 29 | Myositis (HP:0100614) | 3.77039453 |
| 30 | Bronchitis (HP:0012387) | 3.76765727 |
| 31 | Nasal polyposis (HP:0100582) | 3.76384567 |
| 32 | Recurrent viral infections (HP:0004429) | 3.74138061 |
| 33 | Thyroiditis (HP:0100646) | 3.63744811 |
| 34 | Hypoplasia of the thymus (HP:0000778) | 3.58160086 |
| 35 | Hypergammaglobulinemia (HP:0010702) | 3.50400952 |
| 36 | Leukocytosis (HP:0001974) | 3.47139652 |
| 37 | Recurrent sinusitis (HP:0011108) | 3.45496023 |
| 38 | Joint swelling (HP:0001386) | 3.42145819 |
| 39 | Eosinophilia (HP:0001880) | 3.22936579 |
| 40 | Abnormality of the nasal mucosa (HP:0000433) | 3.13797729 |
| 41 | Recurrent otitis media (HP:0000403) | 3.03194278 |
| 42 | Reduced subcutaneous adipose tissue (HP:0003758) | 3.00141412 |
| 43 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.99316608 |
| 44 | Granulocytopenia (HP:0001913) | 2.96077343 |
| 45 | Hemoptysis (HP:0002105) | 2.95904415 |
| 46 | Recurrent skin infections (HP:0001581) | 2.94037560 |
| 47 | Basal cell carcinoma (HP:0002671) | 2.90598684 |
| 48 | Vasculitis (HP:0002633) | 2.83228596 |
| 49 | Gastrointestinal infarctions (HP:0005244) | 2.77295835 |
| 50 | Cheilitis (HP:0100825) | 2.71619688 |
| 51 | Lymphoma (HP:0002665) | 2.68324618 |
| 52 | Agammaglobulinemia (HP:0004432) | 2.66038224 |
| 53 | Optic neuritis (HP:0100653) | 2.64505475 |
| 54 | Retrobulbar optic neuritis (HP:0100654) | 2.64505475 |
| 55 | Thrombocytosis (HP:0001894) | 2.52995448 |
| 56 | Recurrent abscess formation (HP:0002722) | 2.45264270 |
| 57 | Gastrointestinal stroma tumor (HP:0100723) | 2.41668523 |
| 58 | Meningitis (HP:0001287) | 2.41294044 |
| 59 | Pulmonary infiltrates (HP:0002113) | 2.39184950 |
| 60 | Poikiloderma (HP:0001029) | 2.32337170 |
| 61 | Emphysema (HP:0002097) | 2.29108822 |
| 62 | Obstructive lung disease (HP:0006536) | 2.26809208 |
| 63 | Chronic obstructive pulmonary disease (HP:0006510) | 2.26809208 |
| 64 | Mediastinal lymphadenopathy (HP:0100721) | 2.24962864 |
| 65 | Increased density of long bones (HP:0006392) | 2.21968734 |
| 66 | Orchitis (HP:0100796) | 2.20654311 |
| 67 | Autoimmune thrombocytopenia (HP:0001973) | 2.20287641 |
| 68 | Encephalitis (HP:0002383) | 2.17829427 |
| 69 | Bronchiectasis (HP:0002110) | 2.15052978 |
| 70 | Hepatitis (HP:0012115) | 2.12741189 |
| 71 | Amyotrophic lateral sclerosis (HP:0007354) | 2.10736231 |
| 72 | Chronic sinusitis (HP:0011109) | 2.08066305 |
| 73 | Entropion (HP:0000621) | 2.04350161 |
| 74 | Abnormality of the endocardium (HP:0004306) | 2.04268251 |
| 75 | Abnormality of the prostate (HP:0008775) | 1.99265721 |
| 76 | Keratoconjunctivitis sicca (HP:0001097) | 1.97846514 |
| 77 | Gingivitis (HP:0000230) | 1.93185472 |
| 78 | Seborrheic dermatitis (HP:0001051) | 1.92951396 |
| 79 | Pulmonary fibrosis (HP:0002206) | 1.86733547 |
| 80 | Skin rash (HP:0000988) | 1.86186404 |
| 81 | Microcytic anemia (HP:0001935) | 1.84689126 |
| 82 | Papilloma (HP:0012740) | 1.83267966 |
| 83 | Verrucae (HP:0200043) | 1.83267966 |
| 84 | Gangrene (HP:0100758) | 1.79810850 |
| 85 | Increased IgE level (HP:0003212) | 1.77101017 |
| 86 | Arthralgia (HP:0002829) | 1.76540000 |
| 87 | Keratoconjunctivitis (HP:0001096) | 1.76495173 |
| 88 | Skin ulcer (HP:0200042) | 1.75692937 |
| 89 | Ureteral stenosis (HP:0000071) | 1.75021895 |
| 90 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.73787886 |
| 91 | Inflammation of the large intestine (HP:0002037) | 1.71102237 |
| 92 | Gastrointestinal inflammation (HP:0004386) | 1.71088442 |
| 93 | Neutropenia (HP:0001875) | 1.66593418 |
| 94 | Spontaneous hematomas (HP:0007420) | 1.65827657 |
| 95 | Abnormality of DNA repair (HP:0003254) | 1.64536340 |
| 96 | Basal ganglia calcification (HP:0002135) | 1.63946892 |
| 97 | Anorexia (HP:0002039) | 1.63599261 |
| 98 | Large eyes (HP:0001090) | 1.62908664 |
| 99 | Pulmonary embolism (HP:0002204) | 1.60129671 |
| 100 | Polyneuropathy (HP:0001271) | 1.60033254 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.50985852 |
| 2 | MAP4K1 | 5.43836175 |
| 3 | FGFR4 | 5.18544631 |
| 4 | IKBKE | 3.87712213 |
| 5 | ZAP70 | 3.64589523 |
| 6 | JAK3 | 3.57138907 |
| 7 | TYK2 | 3.40544531 |
| 8 | FGFR3 | 2.69968951 |
| 9 | KDR | 2.66535381 |
| 10 | TESK2 | 2.52295969 |
| 11 | ITK | 2.43230483 |
| 12 | MAP3K12 | 2.37458891 |
| 13 | JAK1 | 2.23841039 |
| 14 | STK10 | 2.15966436 |
| 15 | TBK1 | 2.13462040 |
| 16 | KIT | 2.10863783 |
| 17 | LCK | 2.10501200 |
| 18 | BLK | 1.80645704 |
| 19 | NLK | 1.64305909 |
| 20 | MAP3K14 | 1.49733143 |
| 21 | GRK6 | 1.42800456 |
| 22 | TEC | 1.31355166 |
| 23 | SYK | 1.27720833 |
| 24 | PRKCH | 1.27461249 |
| 25 | MAP3K13 | 1.24337549 |
| 26 | HCK | 1.21372760 |
| 27 | CSK | 1.20423827 |
| 28 | NME2 | 1.16192920 |
| 29 | EEF2K | 1.13012003 |
| 30 | PRKCQ | 1.06069165 |
| 31 | MAPK11 | 0.92511099 |
| 32 | BTK | 0.88192576 |
| 33 | LRRK2 | 0.88015796 |
| 34 | JAK2 | 0.86517889 |
| 35 | TESK1 | 0.84704601 |
| 36 | LYN | 0.81936798 |
| 37 | TYRO3 | 0.77375291 |
| 38 | MARK3 | 0.72459350 |
| 39 | TAOK1 | 0.71597400 |
| 40 | IKBKB | 0.69116291 |
| 41 | IRAK4 | 0.64132483 |
| 42 | SIK3 | 0.62894822 |
| 43 | MARK2 | 0.57959496 |
| 44 | MAP2K6 | 0.57808171 |
| 45 | SIK2 | 0.55462213 |
| 46 | CLK1 | 0.55021615 |
| 47 | FGFR1 | 0.54303956 |
| 48 | ILK | 0.52253127 |
| 49 | FYN | 0.51903856 |
| 50 | MYLK | 0.49825095 |
| 51 | TNK2 | 0.48502180 |
| 52 | MST4 | 0.47968910 |
| 53 | CHUK | 0.46878703 |
| 54 | NTRK2 | 0.46756147 |
| 55 | EPHA3 | 0.45796126 |
| 56 | TLK1 | 0.44695335 |
| 57 | INSR | 0.43722049 |
| 58 | CSF1R | 0.43566540 |
| 59 | RPS6KA4 | 0.42500086 |
| 60 | IGF1R | 0.41707021 |
| 61 | PDGFRB | 0.41612093 |
| 62 | FGFR2 | 0.41061623 |
| 63 | PDK1 | 0.40402078 |
| 64 | FES | 0.38903256 |
| 65 | PRKD2 | 0.38234941 |
| 66 | LIMK1 | 0.37348782 |
| 67 | MAP3K7 | 0.35831229 |
| 68 | RPS6KA5 | 0.34829316 |
| 69 | MAP3K10 | 0.34559398 |
| 70 | PIM1 | 0.33678374 |
| 71 | EIF2AK1 | 0.33317828 |
| 72 | TAOK3 | 0.33277847 |
| 73 | CDC7 | 0.32403027 |
| 74 | CSNK1A1L | 0.31700157 |
| 75 | PASK | 0.30240694 |
| 76 | TGFBR2 | 0.26688653 |
| 77 | CSNK1G1 | 0.26387025 |
| 78 | BUB1 | 0.26248823 |
| 79 | RAF1 | 0.25769935 |
| 80 | CSNK1G3 | 0.25718194 |
| 81 | TGFBR1 | 0.23771375 |
| 82 | DMPK | 0.22460098 |
| 83 | HIPK2 | 0.22281511 |
| 84 | MELK | 0.20280375 |
| 85 | MAPK3 | 0.20196118 |
| 86 | EGFR | 0.19788720 |
| 87 | CDK4 | 0.19730233 |
| 88 | ABL1 | 0.18585312 |
| 89 | SIK1 | 0.16178628 |
| 90 | IRAK1 | 0.15901596 |
| 91 | ACVR1B | 0.15805416 |
| 92 | PRKCD | 0.14293838 |
| 93 | SRC | 0.13109815 |
| 94 | SRPK1 | 0.13064194 |
| 95 | DAPK1 | 0.12765553 |
| 96 | ALK | 0.12550371 |
| 97 | ROCK2 | 0.11688438 |
| 98 | DAPK3 | 0.11516114 |
| 99 | BRD4 | 0.11483303 |
| 100 | MAP3K8 | 0.09323809 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 7.27011398 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 4.32214472 |
| 3 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 3.25252386 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.20151922 |
| 5 | Measles_Homo sapiens_hsa05162 | 3.16766250 |
| 6 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.12367242 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.90671504 |
| 8 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.54229713 |
| 9 | Viral myocarditis_Homo sapiens_hsa05416 | 2.42859017 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.41990185 |
| 11 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.33198699 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.10073357 |
| 13 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.86457466 |
| 14 | Leishmaniasis_Homo sapiens_hsa05140 | 1.75963812 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.74978122 |
| 16 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.72256502 |
| 17 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.71695225 |
| 18 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.68771315 |
| 19 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.66817041 |
| 20 | Asthma_Homo sapiens_hsa05310 | 1.60049369 |
| 21 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.57362246 |
| 22 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.53879851 |
| 23 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.35345423 |
| 24 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.32033992 |
| 25 | Hepatitis B_Homo sapiens_hsa05161 | 1.29086633 |
| 26 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.28794852 |
| 27 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.24664554 |
| 28 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.22386410 |
| 29 | Shigellosis_Homo sapiens_hsa05131 | 1.20848117 |
| 30 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.20451220 |
| 31 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.19339225 |
| 32 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.13446549 |
| 33 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.12330962 |
| 34 | Ribosome_Homo sapiens_hsa03010 | 1.10081117 |
| 35 | HTLV-I infection_Homo sapiens_hsa05166 | 1.09665558 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.01495970 |
| 37 | Influenza A_Homo sapiens_hsa05164 | 0.95612601 |
| 38 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.91496334 |
| 39 | Hepatitis C_Homo sapiens_hsa05160 | 0.90028834 |
| 40 | Proteasome_Homo sapiens_hsa03050 | 0.89248494 |
| 41 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.85798017 |
| 42 | Colorectal cancer_Homo sapiens_hsa05210 | 0.85105589 |
| 43 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.84496355 |
| 44 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.83432606 |
| 45 | Malaria_Homo sapiens_hsa05144 | 0.83282216 |
| 46 | RNA degradation_Homo sapiens_hsa03018 | 0.82071754 |
| 47 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.81020716 |
| 48 | Apoptosis_Homo sapiens_hsa04210 | 0.77138397 |
| 49 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.74336719 |
| 50 | Spliceosome_Homo sapiens_hsa03040 | 0.72180511 |
| 51 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.70538618 |
| 52 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.70449101 |
| 53 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.68261547 |
| 54 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.67123988 |
| 55 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.66025498 |
| 56 | Tuberculosis_Homo sapiens_hsa05152 | 0.59636523 |
| 57 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.57134014 |
| 58 | Platelet activation_Homo sapiens_hsa04611 | 0.56458654 |
| 59 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.55402673 |
| 60 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.54383630 |
| 61 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.54027621 |
| 62 | Mismatch repair_Homo sapiens_hsa03430 | 0.53732547 |
| 63 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.52703597 |
| 64 | Basal transcription factors_Homo sapiens_hsa03022 | 0.51276594 |
| 65 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.51006179 |
| 66 | DNA replication_Homo sapiens_hsa03030 | 0.50259481 |
| 67 | Legionellosis_Homo sapiens_hsa05134 | 0.49687996 |
| 68 | Base excision repair_Homo sapiens_hsa03410 | 0.49234610 |
| 69 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.46552310 |
| 70 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.45356150 |
| 71 | Homologous recombination_Homo sapiens_hsa03440 | 0.44205401 |
| 72 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.42488884 |
| 73 | Salmonella infection_Homo sapiens_hsa05132 | 0.41397231 |
| 74 | Other glycan degradation_Homo sapiens_hsa00511 | 0.40873806 |
| 75 | Cell cycle_Homo sapiens_hsa04110 | 0.40347954 |
| 76 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.36741933 |
| 77 | Endocytosis_Homo sapiens_hsa04144 | 0.34793541 |
| 78 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.33676448 |
| 79 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.32681893 |
| 80 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.30972390 |
| 81 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.30149957 |
| 82 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.29810635 |
| 83 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.27565350 |
| 84 | RNA transport_Homo sapiens_hsa03013 | 0.26715347 |
| 85 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.26240022 |
| 86 | Adherens junction_Homo sapiens_hsa04520 | 0.26097552 |
| 87 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.24721851 |
| 88 | Pertussis_Homo sapiens_hsa05133 | 0.23434783 |
| 89 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.19946230 |
| 90 | RNA polymerase_Homo sapiens_hsa03020 | 0.19002496 |
| 91 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.18455597 |
| 92 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.17009301 |
| 93 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.16592868 |
| 94 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.16090364 |
| 95 | Pathways in cancer_Homo sapiens_hsa05200 | 0.15675700 |
| 96 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.13660410 |
| 97 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.12102116 |
| 98 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.11817019 |
| 99 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.10700333 |
| 100 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.10028269 |

