JAK2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of interleukin-12 biosynthetic process (GO:0045075)5.40170934
2NIK/NF-kappaB signaling (GO:0038061)5.31530371
3positive regulation of gamma-delta T cell activation (GO:0046645)4.88370453
4detection of molecule of bacterial origin (GO:0032490)4.73368248
5positive regulation of interleukin-2 biosynthetic process (GO:0045086)4.70390933
6antigen processing and presentation of endogenous antigen (GO:0019883)4.69666442
7macrophage activation involved in immune response (GO:0002281)4.64400527
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.53917601
9antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.49999022
10antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.49999022
11microglial cell activation (GO:0001774)4.44400296
12myeloid dendritic cell differentiation (GO:0043011)4.32074970
13detection of other organism (GO:0098543)4.29588915
14negative thymic T cell selection (GO:0045060)4.20500233
15negative T cell selection (GO:0043383)4.10109700
16positive regulation of natural killer cell differentiation (GO:0032825)4.09814402
17detection of external biotic stimulus (GO:0098581)4.04613274
18regulation of interferon-beta biosynthetic process (GO:0045357)3.93537297
19myeloid dendritic cell activation (GO:0001773)3.92231229
20* positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.84041699
21cellular extravasation (GO:0045123)3.82860307
22detection of bacterium (GO:0016045)3.80898319
23response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.78678782
24response to host immune response (GO:0052572)3.78678782
25macrophage activation (GO:0042116)3.77339237
26positive regulation of humoral immune response (GO:0002922)3.71479504
27regulation of alpha-beta T cell proliferation (GO:0046640)3.70411652
28response to muramyl dipeptide (GO:0032495)3.69922568
29negative regulation of T cell mediated immunity (GO:0002710)3.68872203
30positive regulation of interleukin-2 production (GO:0032743)3.67660670
31neutrophil activation involved in immune response (GO:0002283)3.63634966
32negative regulation of cell killing (GO:0031342)3.61493571
33negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.61493571
34regulation of immunoglobulin secretion (GO:0051023)3.60905499
35regulation of RIG-I signaling pathway (GO:0039535)3.56739041
36myeloid cell activation involved in immune response (GO:0002275)3.55604409
37positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.53765087
38B cell receptor signaling pathway (GO:0050853)3.53567584
39detection of biotic stimulus (GO:0009595)3.52642895
40regulation of gamma-delta T cell activation (GO:0046643)3.52293321
41regulation of gamma-delta T cell differentiation (GO:0045586)3.47945407
42positive regulation of interleukin-12 production (GO:0032735)3.47774464
43response to host (GO:0075136)3.43457893
44response to host defenses (GO:0052200)3.43457893
45response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.43457893
46response to type I interferon (GO:0034340)3.42413824
47positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.42093516
48negative regulation of erythrocyte differentiation (GO:0045647)3.41929787
49T cell migration (GO:0072678)3.41575979
50regulation of chronic inflammatory response (GO:0002676)3.40996115
51regulation of T-helper 1 cell differentiation (GO:0045625)3.40330743
52cellular response to type I interferon (GO:0071357)3.40223231
53type I interferon signaling pathway (GO:0060337)3.40223231
54positive regulation of T cell cytokine production (GO:0002726)3.35520048
55regulation of interferon-alpha production (GO:0032647)3.35404477
56positive regulation of isotype switching (GO:0045830)3.34255598
57negative regulation of lymphocyte mediated immunity (GO:0002707)3.34251943
58regulation of interleukin-2 biosynthetic process (GO:0045076)3.34216176
59positive regulation of alpha-beta T cell proliferation (GO:0046641)3.33101471
60positive regulation of interleukin-17 production (GO:0032740)3.31443516
61neutrophil mediated immunity (GO:0002446)3.30868766
62positive regulation of interferon-alpha production (GO:0032727)3.26588841
63regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.26010943
64regulation of interleukin-12 production (GO:0032655)3.24908583
65regulation of tolerance induction (GO:0002643)3.24751784
66dendritic cell differentiation (GO:0097028)3.24454025
67response to interleukin-15 (GO:0070672)3.23083569
68natural killer cell mediated cytotoxicity (GO:0042267)3.22848626
69natural killer cell mediated immunity (GO:0002228)3.22848626
70* JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.21397168
71CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.21377445
72T-helper cell differentiation (GO:0042093)3.21377445
73positive regulation of mast cell activation (GO:0033005)3.21159866
74germinal center formation (GO:0002467)3.20182145
75positive regulation by organism of defense response of other organism involved in symbiotic interact3.20067829
76modulation by symbiont of host immune response (GO:0052553)3.20067829
77positive regulation by symbiont of host defense response (GO:0052509)3.20067829
78modulation by symbiont of host defense response (GO:0052031)3.20067829
79modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.20067829
80modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.20067829
81positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.19750987
82production of molecular mediator involved in inflammatory response (GO:0002532)3.19118280
83regulation of T-helper cell differentiation (GO:0045622)3.15406673
84regulation of dendritic cell antigen processing and presentation (GO:0002604)3.15364373
85granulocyte activation (GO:0036230)3.12784586
86regulation of mast cell degranulation (GO:0043304)3.12552764
87positive regulation of cellular amide metabolic process (GO:0034250)3.11720983
88* interferon-gamma-mediated signaling pathway (GO:0060333)3.10982681
89negative regulation of interleukin-12 production (GO:0032695)3.10542778
90lipopolysaccharide-mediated signaling pathway (GO:0031663)3.09892759
91regulation of T cell tolerance induction (GO:0002664)3.08761000
92defense response to protozoan (GO:0042832)3.08491483
93regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.07977776
94positive regulation of B cell mediated immunity (GO:0002714)3.06778569
95positive regulation of immunoglobulin mediated immune response (GO:0002891)3.06778569
96regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)3.06765183
97neutrophil activation (GO:0042119)3.06758182
98response to peptidoglycan (GO:0032494)3.05770782
99thymic T cell selection (GO:0045061)3.04675186
100tolerance induction (GO:0002507)3.04352530
101regulation of hypersensitivity (GO:0002883)3.03631302
102positive thymic T cell selection (GO:0045059)3.02426041
103immunoglobulin mediated immune response (GO:0016064)3.01924269
104myeloid leukocyte mediated immunity (GO:0002444)3.00916617
105positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.00328713
106CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.98825356
107regulation of isotype switching to IgG isotypes (GO:0048302)2.98588418
108regulation of mast cell activation (GO:0033003)2.98335885
109positive regulation of antigen processing and presentation (GO:0002579)2.97940740
110B cell mediated immunity (GO:0019724)2.96466325
111leukocyte aggregation (GO:0070486)2.96341058
112regulation of mast cell activation involved in immune response (GO:0033006)2.96094200
113positive regulation of tolerance induction (GO:0002645)2.95709311
114regulation of B cell differentiation (GO:0045577)2.95670585
115T cell selection (GO:0045058)2.95594655
116positive regulation of toll-like receptor signaling pathway (GO:0034123)2.95348052
117response to protozoan (GO:0001562)2.94297077
118positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.94110942
119positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.93411844
120regulation of T-helper 2 cell differentiation (GO:0045628)2.91325913
121positive regulation of type 2 immune response (GO:0002830)2.90454512
122T-helper 1 type immune response (GO:0042088)2.89231940
123regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.85431305
124T cell costimulation (GO:0031295)2.85270893
125positive regulation of cytokine biosynthetic process (GO:0042108)2.84405367
126regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.83820576
127regulation of myeloid leukocyte mediated immunity (GO:0002886)2.83301470
128cellular response to interleukin-15 (GO:0071350)2.82876785
129negative regulation of leukocyte mediated immunity (GO:0002704)2.82682862
130lymphocyte costimulation (GO:0031294)2.82656285
131positive regulation of granulocyte differentiation (GO:0030854)2.82100820
132T cell differentiation involved in immune response (GO:0002292)2.81643064
133alpha-beta T cell differentiation involved in immune response (GO:0002293)2.81643064
134alpha-beta T cell activation involved in immune response (GO:0002287)2.81643064
135regulation of B cell receptor signaling pathway (GO:0050855)2.80883680
136hepatocyte apoptotic process (GO:0097284)2.80868298
137positive regulation of activated T cell proliferation (GO:0042104)2.80134462
138positive regulation of DNA recombination (GO:0045911)2.79096776
139cellular response to ethanol (GO:0071361)2.78886670
140positive regulation of T-helper cell differentiation (GO:0045624)2.78488973
141regulation of vitamin D biosynthetic process (GO:0060556)2.77893701
142positive regulation of mast cell activation involved in immune response (GO:0033008)2.76920962
143positive regulation of mast cell degranulation (GO:0043306)2.76920962
144positive regulation of interferon-beta production (GO:0032728)2.76911230
145leukocyte degranulation (GO:0043299)2.76770457
146respiratory burst (GO:0045730)2.76758525
147negative regulation of B cell proliferation (GO:0030889)2.76291849
148positive regulation of B cell differentiation (GO:0045579)2.74552502
149antigen processing and presentation via MHC class Ib (GO:0002475)2.73958056
150natural killer cell activation (GO:0030101)2.73741687
151regulation of type 2 immune response (GO:0002828)2.72949220
152negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.72426425
153regulation of necroptotic process (GO:0060544)2.71133028

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse6.27766020
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.48368085
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.80785964
4IRF8_21731497_ChIP-ChIP_J774_Mouse4.60787142
5BP1_19119308_ChIP-ChIP_Hs578T_Human4.31467469
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.21117692
7IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.88784270
8* STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.62227081
9* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.55689070
10EGR1_19374776_ChIP-ChIP_THP-1_Human3.34205276
11* IRF8_27001747_Chip-Seq_BMDM_Mouse3.32089267
12* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.11224285
13RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human3.08809042
14* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.96783000
15STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.90090813
16MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.87834556
17STAT4_19710469_ChIP-ChIP_TH1__Mouse2.87178271
18SMAD_19615063_ChIP-ChIP_OVARY_Human2.82160641
19* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.60895911
20RUNX_20019798_ChIP-Seq_JUKART_Human2.60812347
21FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.44769272
22Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.35766578
23MYB_26560356_Chip-Seq_TH2_Human2.35073976
24SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.18101192
25MAF_26560356_Chip-Seq_TH1_Human2.15327877
26MYB_26560356_Chip-Seq_TH1_Human1.97687530
27BRD4_27068464_Chip-Seq_AML-cells_Mouse1.74202770
28MYC_22102868_ChIP-Seq_BL_Human1.68424485
29VDR_24787735_ChIP-Seq_THP-1_Human1.67876867
30* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.65066978
31* TCF7_22412390_ChIP-Seq_EML_Mouse1.64498705
32TP63_17297297_ChIP-ChIP_HaCaT_Human1.62086597
33SCL_19346495_ChIP-Seq_HPC-7_Human1.61848602
34VDR_24763502_ChIP-Seq_THP-1_Human1.61718907
35GATA1_22025678_ChIP-Seq_K562_Human1.59321938
36* GATA3_27048872_Chip-Seq_THYMUS_Human1.58474437
37* SPI1_23547873_ChIP-Seq_NB4_Human1.58248020
38CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.55151969
39KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.55130314
40* PU_27001747_Chip-Seq_BMDM_Mouse1.54048566
41VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.52230820
42STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.51471783
43UTX_26944678_Chip-Seq_JUKART_Human1.47766960
44RUNX1_22412390_ChIP-Seq_EML_Mouse1.42483188
45VDR_21846776_ChIP-Seq_THP-1_Human1.41053997
46PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.36190664
47NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.35833249
48SPI1_23127762_ChIP-Seq_K562_Human1.34995994
49LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.33554287
50KDM2B_26808549_Chip-Seq_DND41_Human1.29413897
51BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.28885903
52LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.26795480
53KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.26078829
54GATA3_26560356_Chip-Seq_TH2_Human1.22314900
55FOXO3_23340844_ChIP-Seq_DLD1_Human1.19855205
56PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15467421
57KDM2B_26808549_Chip-Seq_SUP-B15_Human1.15145483
58GATA2_21666600_ChIP-Seq_HMVEC_Human1.14192230
59MAF_26560356_Chip-Seq_TH2_Human1.13799659
60E2F7_22180533_ChIP-Seq_HELA_Human1.13594077
61FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.13364772
62E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.12994100
63NOTCH1_21737748_ChIP-Seq_TLL_Human1.11856193
64NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.09375565
65* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.03507895
66CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02383010
67SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.02358061
68SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.02358061
69GATA2_22383799_ChIP-Seq_G1ME_Mouse1.01470759
70KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.01324743
71TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.01006685
72* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00056452
73* GATA1_19941827_ChIP-Seq_MEL86_Mouse0.98475527
74SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.97382974
75* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.95723434
76RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.95514354
77CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.94972330
78KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.94563756
79CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.93253958
80SMRT_27268052_Chip-Seq_Bcells_Human0.92109303
81VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.91669735
82ELK3_25401928_ChIP-Seq_HUVEC_Human0.91380595
83SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.91060356
84GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.91001526
85KDM2B_26808549_Chip-Seq_JURKAT_Human0.90745854
86PPAR_26484153_Chip-Seq_NCI-H1993_Human0.89514810
87JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.85027921
88* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.84700961
89THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.83942635
90* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.83887542
91* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.83492847
92CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.82999634
93GATA2_19941826_ChIP-Seq_K562_Human0.82597687
94SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.82385995
95* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80650698
96MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.80161841
97UBF1/2_26484160_Chip-Seq_HMECs_Human0.79773368
98* SALL4_22934838_ChIP-ChIP_CD34+_Human0.78778926
99* GATA1_19941827_ChIP-Seq_MEL_Mouse0.77067810
100CJUN_26792858_Chip-Seq_BT549_Human0.76535178
101RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.76133230
102ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.75316966
103GATA1_19941826_ChIP-Seq_K562_Human0.73447530
104PRDM14_20953172_ChIP-Seq_ESCs_Human0.72285708
105JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.71076364
106GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.70804125
107SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.70542327
108RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.70118194
109TP53_16413492_ChIP-PET_HCT116_Human0.69177648
110KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.68735459
111CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.68197948
112PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.68163510
113CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.67914794
114EGR1_19032775_ChIP-ChIP_M12_Human0.67414853
115SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.67304629
116* BRD4_25478319_ChIP-Seq_HGPS_Human0.66295482
117RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.66102279
118NCOR1_26117541_ChIP-Seq_K562_Human0.66048113
119* POU3F2_20337985_ChIP-ChIP_501MEL_Human0.65835521
120PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.64349305
121GATA3_26560356_Chip-Seq_TH1_Human0.64296979
122FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.62973410
123ER_23166858_ChIP-Seq_MCF-7_Human0.61793808

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.30288403
2MP0003303_peritoneal_inflammation3.71282886
3MP0000685_abnormal_immune_system3.54041662
4MP0003436_decreased_susceptibility_to3.35261918
5MP0005671_abnormal_response_to3.33548003
6MP0009785_altered_susceptibility_to3.21951080
7MP0005387_immune_system_phenotype3.20897828
8MP0001790_abnormal_immune_system3.20897828
9MP0004510_myositis3.05308020
10MP0005000_abnormal_immune_tolerance2.96983524
11MP0002148_abnormal_hypersensitivity_rea2.90862685
12MP0003300_gastrointestinal_ulcer2.79718270
13MP0001800_abnormal_humoral_immune2.79045426
14MP0002138_abnormal_hepatobiliary_system2.61267397
15MP0002452_abnormal_antigen_presenting2.56929040
16MP0002166_altered_tumor_susceptibility2.56305186
17MP0005025_abnormal_response_to2.52473350
18MP0002723_abnormal_immune_serum2.51172620
19MP0002006_tumorigenesis2.50927300
20MP0003763_abnormal_thymus_physiology2.47898979
21MP0002419_abnormal_innate_immunity2.37085352
22MP0001819_abnormal_immune_cell2.30544224
23MP0002420_abnormal_adaptive_immunity2.28348965
24MP0006082_CNS_inflammation2.24640133
25MP0002405_respiratory_system_inflammati2.15970178
26MP0001853_heart_inflammation2.13922054
27MP0003724_increased_susceptibility_to2.13754609
28MP0005310_abnormal_salivary_gland2.11273598
29MP0003656_abnormal_erythrocyte_physiolo2.04901776
30MP0010155_abnormal_intestine_physiology2.02390845
31MP0004947_skin_inflammation1.99822991
32MP0008260_abnormal_autophagy1.96220773
33* MP0002398_abnormal_bone_marrow1.94938033
34MP0003172_abnormal_lysosome_physiology1.94081631
35MP0009333_abnormal_splenocyte_physiolog1.88702347
36* MP0000716_abnormal_immune_system1.83122641
37MP0002254_reproductive_system_inflammat1.80082952
38MP0001873_stomach_inflammation1.76775572
39MP0005076_abnormal_cell_differentiation1.70426387
40MP0010352_gastrointestinal_tract_polyps1.68892902
41MP0003448_altered_tumor_morphology1.68032148
42MP0001533_abnormal_skeleton_physiology1.66419640
43MP0001845_abnormal_inflammatory_respons1.65971571
44MP0004883_abnormal_blood_vessel1.60540585
45MP0002877_abnormal_melanocyte_morpholog1.55523151
46MP0005464_abnormal_platelet_physiology1.52769160
47MP0001348_abnormal_lacrimal_gland1.49346232
48MP0009764_decreased_sensitivity_to1.46953179
49* MP0002429_abnormal_blood_cell1.44610869
50* MP0000689_abnormal_spleen_morphology1.41503099
51MP0003191_abnormal_cellular_cholesterol1.40988221
52* MP0002722_abnormal_immune_system1.40947397
53MP0002009_preneoplasia1.40360868
54MP0000569_abnormal_digit_pigmentation1.37688824
55MP0002332_abnormal_exercise_endurance1.36236512
56MP0000015_abnormal_ear_pigmentation1.35751174
57MP0003866_abnormal_defecation1.35279266
58MP0002396_abnormal_hematopoietic_system1.34814885
59MP0008004_abnormal_stomach_pH1.32975736
60MP0005164_abnormal_response_to1.25583200
61MP0003091_abnormal_cell_migration1.25544414
62MP0000703_abnormal_thymus_morphology1.25387646
63MP0002998_abnormal_bone_remodeling1.24955335
64MP0009278_abnormal_bone_marrow1.22921276
65MP0002933_joint_inflammation1.20990598
66MP0003690_abnormal_glial_cell1.20980453
67MP0008469_abnormal_protein_level1.20280120
68MP0010307_abnormal_tumor_latency1.17597314
69MP0002132_abnormal_respiratory_system1.17490593
70MP0003646_muscle_fatigue1.17187038
71MP0004130_abnormal_muscle_cell1.14405277
72MP0003221_abnormal_cardiomyocyte_apopto1.12953939
73MP0000858_altered_metastatic_potential1.12893912
74MP0003453_abnormal_keratinocyte_physiol1.11456509
75* MP0004808_abnormal_hematopoietic_stem1.08660619
76* MP0001545_abnormal_hematopoietic_system1.06467695
77* MP0005397_hematopoietic_system_phenotyp1.06467695
78MP0000604_amyloidosis1.04913208
79MP0004484_altered_response_of1.04115640
80MP0008057_abnormal_DNA_replication1.02122961
81MP0006054_spinal_hemorrhage1.02052041
82MP0000490_abnormal_crypts_of1.01523283
83MP0002163_abnormal_gland_morphology1.00098615
84MP0005174_abnormal_tail_pigmentation0.98127347
85MP0004381_abnormal_hair_follicle0.92617222
86MP0001851_eye_inflammation0.92605166
87MP0003183_abnormal_peptide_metabolism0.89862245
88MP0000465_gastrointestinal_hemorrhage0.89461846
89MP0003075_altered_response_to0.84949389
90MP0002277_abnormal_respiratory_mucosa0.82971336
91MP0005167_abnormal_blood-brain_barrier0.81453101
92MP0005075_abnormal_melanosome_morpholog0.80036899
93MP0005390_skeleton_phenotype0.79628413
94MP0003045_fibrosis0.78543214
95MP0003566_abnormal_cell_adhesion0.77684794
96MP0000343_altered_response_to0.77278256
97* MP0001881_abnormal_mammary_gland0.77251358
98* MP0000627_abnormal_mammary_gland0.77112258
99MP0009763_increased_sensitivity_to0.71880544
100MP0004084_abnormal_cardiac_muscle0.71798947
101MP0004185_abnormal_adipocyte_glucose0.70469587
102MP0010234_abnormal_vibrissa_follicle0.69836957
103MP0005166_decreased_susceptibility_to0.69510986
104MP0003828_pulmonary_edema0.69237954
105MP0003705_abnormal_hypodermis_morpholog0.69064786
106MP0009765_abnormal_xenobiotic_induced0.68740465
107MP0008874_decreased_physiological_sensi0.68015846
108MP0000249_abnormal_blood_vessel0.67898112
109MP0000733_abnormal_muscle_development0.67069267
110MP0001346_abnormal_lacrimal_gland0.66638961
111MP0000767_abnormal_smooth_muscle0.65692614
112MP0005023_abnormal_wound_healing0.64511523
113MP0001663_abnormal_digestive_system0.63680457
114* MP0002019_abnormal_tumor_incidence0.62437424
115MP0004036_abnormal_muscle_relaxation0.61524332
116* MP0003795_abnormal_bone_structure0.60975602
117MP0001216_abnormal_epidermal_layer0.60761927
118MP0005376_homeostasis/metabolism_phenot0.60507627
119MP0005451_abnormal_body_composition0.58866953
120MP0005058_abnormal_lysosome_morphology0.57443801
121MP0001915_intracranial_hemorrhage0.57240520
122MP0009115_abnormal_fat_cell0.56122394
123MP0005409_darkened_coat_color0.52844614
124MP0002136_abnormal_kidney_physiology0.52023635
125MP0005621_abnormal_cell_physiology0.51673681
126MP0001191_abnormal_skin_condition0.51193080
127MP0005666_abnormal_adipose_tissue0.51126066
128MP0000371_diluted_coat_color0.50038583

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)5.68859378
2Optic neuritis (HP:0100653)4.80594790
3Retrobulbar optic neuritis (HP:0100654)4.80594790
4Recurrent abscess formation (HP:0002722)4.67456259
5Recurrent bacterial skin infections (HP:0005406)4.57900637
6Recurrent fungal infections (HP:0002841)4.55962281
7Stomatitis (HP:0010280)4.49834796
8Orchitis (HP:0100796)4.43121227
9Myositis (HP:0100614)4.41393247
10Elevated erythrocyte sedimentation rate (HP:0003565)4.37055479
11Autoimmune thrombocytopenia (HP:0001973)4.34774011
12Recurrent viral infections (HP:0004429)4.32477656
13Mediastinal lymphadenopathy (HP:0100721)4.24204272
14Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.13220306
15Vasculitis (HP:0002633)4.01298755
16Pulmonary infiltrates (HP:0002113)3.76333996
17Abnormality of T cell number (HP:0011839)3.57406677
18Prolonged bleeding time (HP:0003010)3.47827819
19Increased IgM level (HP:0003496)3.45690916
20Recurrent cutaneous fungal infections (HP:0011370)3.34773939
21Chronic mucocutaneous candidiasis (HP:0002728)3.34773939
22T lymphocytopenia (HP:0005403)3.33344573
23Chronic otitis media (HP:0000389)3.31766893
24Recurrent skin infections (HP:0001581)3.29913863
25Abnormal delayed hypersensitivity skin test (HP:0002963)3.29879199
26Abnormality of macrophages (HP:0004311)3.27701114
27Recurrent gram-negative bacterial infections (HP:0005420)3.23178372
28Abnormality of the fingertips (HP:0001211)3.06210600
29Prostate neoplasm (HP:0100787)3.03401557
30* Gingival bleeding (HP:0000225)2.98937829
31Hemoptysis (HP:0002105)2.98247452
32Abnormality of T cells (HP:0002843)2.97084792
33Chronic obstructive pulmonary disease (HP:0006510)2.93098045
34Obstructive lung disease (HP:0006536)2.93098045
35* Epistaxis (HP:0000421)2.92337842
36Gingivitis (HP:0000230)2.88183240
37* Arterial thrombosis (HP:0004420)2.87963018
38Hematochezia (HP:0002573)2.86630320
39Pustule (HP:0200039)2.86152897
40Keratoconjunctivitis sicca (HP:0001097)2.84044788
41Chronic diarrhea (HP:0002028)2.79869900
42Urticaria (HP:0001025)2.76813339
43Abnormality of the prostate (HP:0008775)2.76561732
44Osteolytic defects of the phalanges of the hand (HP:0009771)2.72290643
45Osteolytic defects of the hand bones (HP:0009699)2.72290643
46Meningitis (HP:0001287)2.71867695
47Panhypogammaglobulinemia (HP:0003139)2.69279037
48Periodontitis (HP:0000704)2.68305387
49Hypergammaglobulinemia (HP:0010702)2.66824747
50IgA deficiency (HP:0002720)2.65748108
51Increased IgE level (HP:0003212)2.64883448
52Keratoconjunctivitis (HP:0001096)2.61509609
53Abnormality of T cell physiology (HP:0011840)2.61351208
54Recurrent bronchitis (HP:0002837)2.60618063
55Persistence of primary teeth (HP:0006335)2.60067776
56Interstitial pulmonary disease (HP:0006530)2.59883043
57Nasal polyposis (HP:0100582)2.57233999
58Amyloidosis (HP:0011034)2.55073220
59Basal ganglia calcification (HP:0002135)2.51569370
60Eosinophilia (HP:0001880)2.50824082
61Inflammation of the large intestine (HP:0002037)2.48550965
62Porencephaly (HP:0002132)2.46521075
63Cellulitis (HP:0100658)2.40993014
64Autoimmune hemolytic anemia (HP:0001890)2.34322106
65Severe combined immunodeficiency (HP:0004430)2.34071068
66Gastrointestinal inflammation (HP:0004386)2.32955323
67Absent frontal sinuses (HP:0002688)2.32016729
68Joint swelling (HP:0001386)2.30964784
69Episodic fever (HP:0001954)2.30962703
70* Leukocytosis (HP:0001974)2.30166379
71Increased density of long bones (HP:0006392)2.27298092
72Encephalitis (HP:0002383)2.26705427
73Abnormality of eosinophils (HP:0001879)2.26327073
74Abnormality of cells of the lymphoid lineage (HP:0012140)2.25762938
75Colitis (HP:0002583)2.25166459
76Lymphopenia (HP:0001888)2.24197876
77* Gastrointestinal infarctions (HP:0005244)2.23242760
78Gangrene (HP:0100758)2.22486186
79Abnormality of the nasal mucosa (HP:0000433)2.20724700
80IgG deficiency (HP:0004315)2.19941565
81Slow saccadic eye movements (HP:0000514)2.18379779
82Pulmonary embolism (HP:0002204)2.17734715
83Abnormality of the vasculature of the conjunctiva (HP:0008054)2.15953412
84Gastrointestinal stroma tumor (HP:0100723)2.15821335
85Combined immunodeficiency (HP:0005387)2.15421468
86Spontaneous hematomas (HP:0007420)2.15080188
87Emphysema (HP:0002097)2.13962408
88Abnormality of the pericardium (HP:0001697)2.13946513
89* Chest pain (HP:0100749)2.10446829
90* Vertigo (HP:0002321)2.10039151
91Abnormality of glycolipid metabolism (HP:0010969)2.09748186
92Abnormality of liposaccharide metabolism (HP:0010968)2.09748186
93Abnormality of glycosphingolipid metabolism (HP:0004343)2.09748186
94Polyneuropathy (HP:0001271)2.08517768
95Thyroiditis (HP:0100646)2.07184318
96Thick nail (HP:0001805)2.07003577
97Glomerulopathy (HP:0100820)2.06877807
98Tetraparesis (HP:0002273)2.04862047
99Agammaglobulinemia (HP:0004432)2.03078878
100Granulocytopenia (HP:0001913)1.99847370
101Osteomyelitis (HP:0002754)1.98525077
102Asymmetric septal hypertrophy (HP:0001670)1.97823120
103Abnormality of the pleura (HP:0002103)1.97560673
104Anorexia (HP:0002039)1.97385079
105* Arthralgia (HP:0002829)1.97257036
106Viral hepatitis (HP:0006562)1.95970181
107Spinal cord lesions (HP:0100561)1.95464371
108Syringomyelia (HP:0003396)1.95464371
109Conjunctival telangiectasia (HP:0000524)1.93403994
110Postural instability (HP:0002172)1.92812008
111Disinhibition (HP:0000734)1.91803513
112Purpura (HP:0000979)1.91745046
113Increased serum ferritin (HP:0003281)1.88332607
114Poikilocytosis (HP:0004447)1.87879871
115Petechiae (HP:0000967)1.87757905
116Microcytic anemia (HP:0001935)1.87431808
117* Acute myeloid leukemia (HP:0004808)1.87087354
118Abnormality of the endocardium (HP:0004306)1.86618201
119B lymphocytopenia (HP:0010976)1.86426904
120Abnormality of B cell number (HP:0010975)1.86426904
121Restrictive lung disease (HP:0002091)1.86223477
122Abnormal platelet volume (HP:0011876)1.85725473
123Subacute progressive viral hepatitis (HP:0006572)1.83410504
124Abnormality of iron homeostasis (HP:0011031)1.81452459
125Neoplasm of the tracheobronchial system (HP:0100552)1.81059124
126Skin ulcer (HP:0200042)1.80935782
127Sepsis (HP:0100806)1.79833845
128Hypochromic microcytic anemia (HP:0004840)1.78303291
129* Thrombophlebitis (HP:0004418)1.77032696
130Recurrent pneumonia (HP:0006532)1.75377653
131Papillary thyroid carcinoma (HP:0002895)1.74338717
132Keratitis (HP:0000491)1.73415799

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K144.96648452
2TXK3.97683121
3MAP4K13.37618507
4TYK23.33048236
5IKBKB2.89792598
6TBK12.83284770
7MAP3K132.73352661
8* JAK32.69185289
9JAK12.54796573
10IKBKE2.53353295
11RIPK42.52842264
12CHUK2.43882575
13PRPF4B2.23853288
14LATS11.97126261
15ZAP701.86224562
16PIK3CG1.85084877
17EPHB11.82306787
18FGFR31.76019051
19EPHA31.73649005
20IRAK41.73608077
21IRAK31.64632638
22FGFR41.57753933
23NEK91.51025936
24MATK1.50720593
25STK101.42468228
26TAOK31.40518014
27TRIB31.36486552
28BLK1.34095039
29TEC1.31938341
30CSK1.31848329
31TAOK11.30615732
32STK31.30237768
33KIT1.29548293
34CDK121.28172970
35ITK1.26417487
36HCK1.26349872
37RPS6KA41.23176706
38LCK1.21358493
39MST41.19064805
40PIM11.18753452
41GRK71.18279754
42* JAK21.11225012
43PIM21.09425751
44MAP3K61.09039356
45NLK1.08072583
46BTK1.06684107
47MAP3K21.05580566
48SYK1.05176275
49CAMKK21.04658288
50PDGFRB0.95175886
51IRAK20.92550764
52YES10.92058577
53TNK20.88653231
54PRKCQ0.87217526
55OBSCN0.86832165
56PBK0.85527096
57MARK30.85274051
58MAP3K50.84744535
59TTN0.81929563
60SGK20.81753627
61CSF1R0.81671901
62DMPK0.79560499
63EEF2K0.79289647
64BMPR20.78823072
65PTK2B0.78105971
66SGK30.78016666
67PTK60.77452320
68WNK10.77185497
69BMX0.76866292
70RAF10.76809377
71LRRK20.76638012
72ERN10.71729651
73STK40.71115315
74TRPM70.71043269
75RIPK10.69163873
76KSR20.67119493
77MAP2K30.66721953
78PDPK10.66068643
79MAPK120.65768438
80CDK90.65475988
81MARK20.64686178
82CDC42BPA0.63465016
83LYN0.62816774
84BRD40.62816228
85FRK0.62545941
86* ABL10.62224574
87KSR10.60796264
88RET0.60399846
89MELK0.59600905
90FGR0.57325246
91ALK0.56691964
92MAPK70.54656327
93IRAK10.53566670
94CDK60.52710264
95ABL20.52509489
96MAP3K100.51633699
97SIK20.50825389
98MAP3K80.50643963
99MAPKAPK20.50005048
100MAP2K40.49100186
101PRKAA20.48937612
102EGFR0.48689901
103MOS0.47659335
104MAP3K10.47654368
105NUAK10.47648727
106MAP3K70.47125239
107DYRK1B0.45860969
108MAP3K30.44873350
109STK240.44598532
110FYN0.43605367
111PKN20.42110469
112ERBB40.41473648
113HIPK20.41330249
114GRK60.41126563
115MAP3K110.40995426
116PDK10.39212817
117MAPK110.37120445
118TAOK20.36590658
119CLK10.35590495
120TYRO30.34325546
121FES0.33956126
122STK110.33744422
123PRKCH0.33454516
124RPS6KA10.33355333
125LATS20.31834792
126PKN10.31288852
127ACVR1B0.30474572
128SGK10.30043457
129SIK30.29941940
130CDK40.29409400
131TGFBR20.28720579
132PDGFRA0.28544043
133CAMK1D0.28138585

Predicted pathways (KEGG)

RankGene SetZ-score
1Allograft rejection_Homo sapiens_hsa053303.34230546
2NF-kappa B signaling pathway_Homo sapiens_hsa040642.91934322
3Graft-versus-host disease_Homo sapiens_hsa053322.80016812
4* Leishmaniasis_Homo sapiens_hsa051402.63865048
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.57790891
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.50461554
7* Measles_Homo sapiens_hsa051622.28331682
8Autoimmune thyroid disease_Homo sapiens_hsa053202.25039888
9NOD-like receptor signaling pathway_Homo sapiens_hsa046212.22318753
10Osteoclast differentiation_Homo sapiens_hsa043802.19771002
11TNF signaling pathway_Homo sapiens_hsa046682.19063086
12Toll-like receptor signaling pathway_Homo sapiens_hsa046202.19016274
13Asthma_Homo sapiens_hsa053102.15490362
14RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.00240918
15Primary immunodeficiency_Homo sapiens_hsa053401.95566521
16Type I diabetes mellitus_Homo sapiens_hsa049401.91908714
17T cell receptor signaling pathway_Homo sapiens_hsa046601.89804486
18* Toxoplasmosis_Homo sapiens_hsa051451.86252118
19* Jak-STAT signaling pathway_Homo sapiens_hsa046301.76842321
20Legionellosis_Homo sapiens_hsa051341.73737672
21Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.72867382
22B cell receptor signaling pathway_Homo sapiens_hsa046621.66140647
23Malaria_Homo sapiens_hsa051441.62920225
24* Influenza A_Homo sapiens_hsa051641.62044694
25* Herpes simplex infection_Homo sapiens_hsa051681.60793961
26Viral myocarditis_Homo sapiens_hsa054161.56079008
27Pertussis_Homo sapiens_hsa051331.53866163
28Hematopoietic cell lineage_Homo sapiens_hsa046401.52125241
29* Chemokine signaling pathway_Homo sapiens_hsa040621.50329504
30* Tuberculosis_Homo sapiens_hsa051521.47114490
31Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.45844908
32Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.43774418
33Apoptosis_Homo sapiens_hsa042101.41788922
34Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.41639828
35Shigellosis_Homo sapiens_hsa051311.37659640
36Hepatitis B_Homo sapiens_hsa051611.36729939
37Chronic myeloid leukemia_Homo sapiens_hsa052201.34358244
38Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.33713717
39Antigen processing and presentation_Homo sapiens_hsa046121.31836263
40Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.28798730
41Salmonella infection_Homo sapiens_hsa051321.26111057
42Acute myeloid leukemia_Homo sapiens_hsa052211.24227865
43Pancreatic cancer_Homo sapiens_hsa052121.24205616
44Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.23407818
45Rheumatoid arthritis_Homo sapiens_hsa053231.22206817
46Staphylococcus aureus infection_Homo sapiens_hsa051501.20897026
47* Prolactin signaling pathway_Homo sapiens_hsa049171.20851897
48Small cell lung cancer_Homo sapiens_hsa052221.16264411
49African trypanosomiasis_Homo sapiens_hsa051431.13575687
50* AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.11618727
51Hepatitis C_Homo sapiens_hsa051601.02101201
52Other glycan degradation_Homo sapiens_hsa005110.96855443
53Leukocyte transendothelial migration_Homo sapiens_hsa046700.94215323
54Transcriptional misregulation in cancer_Homo sapiens_hsa052020.83431461
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.81316103
56MicroRNAs in cancer_Homo sapiens_hsa052060.80342136
57Amoebiasis_Homo sapiens_hsa051460.80171239
58Epstein-Barr virus infection_Homo sapiens_hsa051690.79832778
59Viral carcinogenesis_Homo sapiens_hsa052030.79761173
60Platelet activation_Homo sapiens_hsa046110.79475620
61HTLV-I infection_Homo sapiens_hsa051660.77413320
62SNARE interactions in vesicular transport_Homo sapiens_hsa041300.76542849
63Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.73690094
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72842228
65Dorso-ventral axis formation_Homo sapiens_hsa043200.70462683
66Phosphatidylinositol signaling system_Homo sapiens_hsa040700.68255954
67p53 signaling pathway_Homo sapiens_hsa041150.68061318
68VEGF signaling pathway_Homo sapiens_hsa043700.66409340
69Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.64765086
70Renal cell carcinoma_Homo sapiens_hsa052110.64424780
71* Adipocytokine signaling pathway_Homo sapiens_hsa049200.63008436
72MAPK signaling pathway_Homo sapiens_hsa040100.60926579
73Prostate cancer_Homo sapiens_hsa052150.60424652
74FoxO signaling pathway_Homo sapiens_hsa040680.59555342
75Insulin resistance_Homo sapiens_hsa049310.58608748
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.56275846
77Non-small cell lung cancer_Homo sapiens_hsa052230.55456170
78GnRH signaling pathway_Homo sapiens_hsa049120.55042788
79HIF-1 signaling pathway_Homo sapiens_hsa040660.53468334
80Colorectal cancer_Homo sapiens_hsa052100.51546009
81Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51468888
82Proteoglycans in cancer_Homo sapiens_hsa052050.50775698
83Fatty acid biosynthesis_Homo sapiens_hsa000610.50339808
84Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.49834541
85mTOR signaling pathway_Homo sapiens_hsa041500.49704680
86Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.49276653
87Sphingolipid signaling pathway_Homo sapiens_hsa040710.49153502
88Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.47210147
89Systemic lupus erythematosus_Homo sapiens_hsa053220.44630849
90Adherens junction_Homo sapiens_hsa045200.43476263
91Type II diabetes mellitus_Homo sapiens_hsa049300.43113914
92Phagosome_Homo sapiens_hsa041450.42896334
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42818504
94Notch signaling pathway_Homo sapiens_hsa043300.42612926
95Endometrial cancer_Homo sapiens_hsa052130.41031641
96Glycosaminoglycan degradation_Homo sapiens_hsa005310.40862604
97Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40050548
98Focal adhesion_Homo sapiens_hsa045100.38586384
99Long-term potentiation_Homo sapiens_hsa047200.37483999
100Pathways in cancer_Homo sapiens_hsa052000.36615972
101Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.36571653
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.36164312
103Insulin signaling pathway_Homo sapiens_hsa049100.35723783
104Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35505533
105Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.34463101
106Endocytosis_Homo sapiens_hsa041440.33302088
107Glioma_Homo sapiens_hsa052140.33244800
108ErbB signaling pathway_Homo sapiens_hsa040120.30691047
109Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.30141918
110Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29204454
111Choline metabolism in cancer_Homo sapiens_hsa052310.27720861
112TGF-beta signaling pathway_Homo sapiens_hsa043500.26938625
113Lysosome_Homo sapiens_hsa041420.26438936
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.26320130
115Inositol phosphate metabolism_Homo sapiens_hsa005620.23625036
116Ras signaling pathway_Homo sapiens_hsa040140.22341791
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.21391905

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