JAKMIP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.79379920
2vocalization behavior (GO:0071625)5.49441113
3regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.23469796
4regulation of short-term neuronal synaptic plasticity (GO:0048172)5.08673472
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.89336633
6synaptic vesicle exocytosis (GO:0016079)4.87998735
7protein localization to synapse (GO:0035418)4.86559538
8regulation of glutamate receptor signaling pathway (GO:1900449)4.73739321
9presynaptic membrane assembly (GO:0097105)4.70435008
10ionotropic glutamate receptor signaling pathway (GO:0035235)4.53200731
11regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.48361668
12neuron recognition (GO:0008038)4.45560812
13neurotransmitter-gated ion channel clustering (GO:0072578)4.43649714
14presynaptic membrane organization (GO:0097090)4.39980589
15regulation of synaptic vesicle exocytosis (GO:2000300)4.39779135
16synaptic vesicle docking involved in exocytosis (GO:0016081)4.30877754
17glutamate receptor signaling pathway (GO:0007215)4.28895082
18glutamate secretion (GO:0014047)4.27786281
19positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.27166847
20postsynaptic membrane organization (GO:0001941)4.25277415
21synaptic transmission, glutamatergic (GO:0035249)4.17983209
22axonal fasciculation (GO:0007413)4.17916585
23neuron-neuron synaptic transmission (GO:0007270)4.12228760
24neuronal action potential propagation (GO:0019227)4.07829765
25gamma-aminobutyric acid transport (GO:0015812)4.05698692
26locomotory exploration behavior (GO:0035641)4.02163776
27behavioral response to nicotine (GO:0035095)4.01773091
28synaptic vesicle maturation (GO:0016188)3.98194454
29dendritic spine morphogenesis (GO:0060997)3.94728375
30regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.91160202
31regulation of synaptic vesicle transport (GO:1902803)3.89904828
32pyrimidine nucleobase catabolic process (GO:0006208)3.85715294
33exploration behavior (GO:0035640)3.82403808
34regulation of neuronal synaptic plasticity (GO:0048168)3.76526057
35neurotransmitter secretion (GO:0007269)3.76178679
36negative regulation of synaptic transmission, GABAergic (GO:0032229)3.76026730
37central nervous system projection neuron axonogenesis (GO:0021952)3.73594826
38cerebellar granule cell differentiation (GO:0021707)3.68612761
39regulation of long-term neuronal synaptic plasticity (GO:0048169)3.67768363
40cell migration in hindbrain (GO:0021535)3.66342162
41layer formation in cerebral cortex (GO:0021819)3.63131869
42regulation of excitatory postsynaptic membrane potential (GO:0060079)3.62542507
43gamma-aminobutyric acid signaling pathway (GO:0007214)3.62064970
44transmission of nerve impulse (GO:0019226)3.60300969
45regulation of synapse structural plasticity (GO:0051823)3.59743124
46positive regulation of synapse assembly (GO:0051965)3.58759470
47positive regulation of synapse maturation (GO:0090129)3.57229449
48membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.55829103
49regulation of postsynaptic membrane potential (GO:0060078)3.52684981
50G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.49649401
51startle response (GO:0001964)3.48868560
52synapse assembly (GO:0007416)3.47203450
53auditory behavior (GO:0031223)3.41100616
54negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.39867575
55positive regulation of membrane potential (GO:0045838)3.39524183
56regulation of synaptic transmission, glutamatergic (GO:0051966)3.36765843
57nonmotile primary cilium assembly (GO:0035058)3.34327803
58regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.33410335
59limb bud formation (GO:0060174)3.33036370
60mechanosensory behavior (GO:0007638)3.30691419
61dendrite morphogenesis (GO:0048813)3.30056081
62regulation of glutamate secretion (GO:0014048)3.29702893
63long-term memory (GO:0007616)3.28820829
64cerebral cortex radially oriented cell migration (GO:0021799)3.26058030
65long-term synaptic potentiation (GO:0060291)3.24958673
66dendrite development (GO:0016358)3.23442411
67synaptic vesicle endocytosis (GO:0048488)3.22645676
68retinal ganglion cell axon guidance (GO:0031290)3.19174114
69regulation of dendritic spine morphogenesis (GO:0061001)3.17781847
70innervation (GO:0060384)3.17724031
71neurotransmitter transport (GO:0006836)3.16553236
72membrane hyperpolarization (GO:0060081)3.15090667
73negative regulation of dendrite development (GO:2000171)3.15082306
74response to histamine (GO:0034776)3.14574242
75positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.14094564
76calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.13824282
77nucleobase catabolic process (GO:0046113)3.13788874
78regulation of synaptic plasticity (GO:0048167)3.13618628
79regulation of synapse maturation (GO:0090128)3.11946024
80positive regulation of neurotransmitter secretion (GO:0001956)3.10460235
81regulation of neurotransmitter secretion (GO:0046928)3.10339332
82positive regulation of synaptic transmission, GABAergic (GO:0032230)3.10119408
83behavioral defense response (GO:0002209)3.08701875
84behavioral fear response (GO:0001662)3.08701875
85C4-dicarboxylate transport (GO:0015740)3.07879260
86negative regulation of microtubule polymerization (GO:0031115)3.07470760
87regulation of respiratory system process (GO:0044065)3.04892271
88establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.04788646
89mitochondrion transport along microtubule (GO:0047497)3.04788646
90cerebellar Purkinje cell differentiation (GO:0021702)3.04709352
91regulation of synapse assembly (GO:0051963)3.04353661
92central nervous system neuron axonogenesis (GO:0021955)3.02800353
93learning (GO:0007612)3.02756282
94negative regulation of dendrite morphogenesis (GO:0050774)3.00451156
95response to auditory stimulus (GO:0010996)2.99457590
96regulation of vesicle fusion (GO:0031338)2.98486834
97glycosphingolipid biosynthetic process (GO:0006688)2.98149745
98membrane depolarization (GO:0051899)2.98061808
99establishment of mitochondrion localization (GO:0051654)2.96578445
100positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.95929138
101synapse organization (GO:0050808)2.94912649
102adult walking behavior (GO:0007628)2.94860104
103proline transport (GO:0015824)2.94758981
104behavioral response to cocaine (GO:0048148)2.94306069
105negative regulation of neurotransmitter transport (GO:0051589)2.94221185
106fear response (GO:0042596)2.92200893
107protein polyglutamylation (GO:0018095)2.91969885
108regulation of action potential (GO:0098900)2.90620750
109regulation of neurotransmitter levels (GO:0001505)2.90486448
110regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.89826141
111regulation of neurotransmitter transport (GO:0051588)2.89718315
112neural tube formation (GO:0001841)2.88934802
113positive regulation of neurotransmitter transport (GO:0051590)2.88772729
114olfactory bulb development (GO:0021772)2.87049174
115substrate-independent telencephalic tangential migration (GO:0021826)2.86718925
116substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.86718925
117positive regulation of action potential (GO:0045760)2.85856107
118regulation of feeding behavior (GO:0060259)2.84288341
119neuronal action potential (GO:0019228)2.82380370
120hippocampus development (GO:0021766)2.81140813
121positive regulation of oligodendrocyte differentiation (GO:0048714)2.80052371
122negative regulation of cytosolic calcium ion concentration (GO:0051481)2.79916443
123protein localization to cilium (GO:0061512)2.79525037
124membrane depolarization during action potential (GO:0086010)2.74643185
125neurofilament cytoskeleton organization (GO:0060052)2.72992544
126regulation of cilium movement (GO:0003352)2.72477221
127forebrain neuron differentiation (GO:0021879)2.70855762
128neuromuscular synaptic transmission (GO:0007274)2.70621936
129glycerophospholipid catabolic process (GO:0046475)2.66236037
130positive regulation of potassium ion transmembrane transport (GO:1901381)2.65184182
131behavioral response to ethanol (GO:0048149)2.62320741
132spinal cord development (GO:0021510)2.60874778
133regulation of microtubule-based movement (GO:0060632)2.60393606
134adult behavior (GO:0030534)2.60347794
135regulation of collateral sprouting (GO:0048670)2.59741096
136synaptic transmission, cholinergic (GO:0007271)2.56416155
137intraciliary transport (GO:0042073)2.54828972
138adaptation of signaling pathway (GO:0023058)2.52404424
139heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.52284488
140epithelial cell differentiation involved in kidney development (GO:0035850)2.49476373
141neuronal ion channel clustering (GO:0045161)2.48389977

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.43218943
2* GBX2_23144817_ChIP-Seq_PC3_Human4.04643054
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.06934420
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.00452650
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.88520382
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.67199498
7REST_21632747_ChIP-Seq_MESCs_Mouse2.55564229
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.53845987
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.53845987
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.52541672
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.50963055
12TAF15_26573619_Chip-Seq_HEK293_Human2.49287808
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.47435484
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40170803
15EED_16625203_ChIP-ChIP_MESCs_Mouse2.35189331
16MTF2_20144788_ChIP-Seq_MESCs_Mouse2.22653184
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.22133384
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.22028835
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.21474631
20CTBP2_25329375_ChIP-Seq_LNCAP_Human2.18091449
21NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.13810160
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.12864105
23SUZ12_27294783_Chip-Seq_ESCs_Mouse2.11381010
24CTBP1_25329375_ChIP-Seq_LNCAP_Human2.09738935
25RNF2_27304074_Chip-Seq_ESCs_Mouse2.09679955
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.05766386
27REST_18959480_ChIP-ChIP_MESCs_Mouse2.00985262
28RARB_27405468_Chip-Seq_BRAIN_Mouse2.00982780
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.99134830
30SALL1_21062744_ChIP-ChIP_HESCs_Human1.96153971
31DROSHA_22980978_ChIP-Seq_HELA_Human1.92575001
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.85519474
33BMI1_23680149_ChIP-Seq_NPCS_Mouse1.83878262
34P300_19829295_ChIP-Seq_ESCs_Human1.76544269
35* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.76467468
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.75044108
37SMAD4_21799915_ChIP-Seq_A2780_Human1.72105497
38IGF1R_20145208_ChIP-Seq_DFB_Human1.70792883
39AR_21572438_ChIP-Seq_LNCaP_Human1.70716890
40* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.68316679
41* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.65683182
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.64663701
43TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62113124
44SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.57219482
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.56430471
46RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.55096868
47ZNF274_21170338_ChIP-Seq_K562_Hela1.54582988
48SMAD3_21741376_ChIP-Seq_EPCs_Human1.54184140
49RNF2_27304074_Chip-Seq_NSC_Mouse1.53854670
50FUS_26573619_Chip-Seq_HEK293_Human1.50713271
51SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.47497676
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46661434
53IKZF1_21737484_ChIP-ChIP_HCT116_Human1.46515556
54TOP2B_26459242_ChIP-Seq_MCF-7_Human1.46253591
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.34877490
56POU5F1_16153702_ChIP-ChIP_HESCs_Human1.34026815
57AR_25329375_ChIP-Seq_VCAP_Human1.33330323
58ER_23166858_ChIP-Seq_MCF-7_Human1.30453076
59CBP_20019798_ChIP-Seq_JUKART_Human1.29784085
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.29784085
61FLI1_27457419_Chip-Seq_LIVER_Mouse1.29270576
62SOX2_21211035_ChIP-Seq_LN229_Gbm1.29171564
63CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.28454048
64HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.28241653
65E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.27819931
66VDR_22108803_ChIP-Seq_LS180_Human1.25919833
67MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.25812482
68MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.23865594
69STAT3_23295773_ChIP-Seq_U87_Human1.22254049
70* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21657781
71ERG_21242973_ChIP-ChIP_JURKAT_Human1.21440986
72TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20743632
73POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20743632
74TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20473642
75BCAT_22108803_ChIP-Seq_LS180_Human1.18619082
76RING1B_27294783_Chip-Seq_ESCs_Mouse1.18442557
77* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17801040
78KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.17043092
79P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16374714
80SMAD_19615063_ChIP-ChIP_OVARY_Human1.16081485
81RUNX2_22187159_ChIP-Seq_PCA_Human1.15808242
82GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15255275
83KLF5_20875108_ChIP-Seq_MESCs_Mouse1.14169320
84ARNT_22903824_ChIP-Seq_MCF-7_Human1.13760498
85CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13413005
86* TCF4_23295773_ChIP-Seq_U87_Human1.12180274
87PCGF2_27294783_Chip-Seq_ESCs_Mouse1.11975643
88TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10885932
89PRDM14_20953172_ChIP-Seq_ESCs_Human1.10872127
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.10207031
91AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08839463
92RING1B_27294783_Chip-Seq_NPCs_Mouse1.08801928
93FLI1_21867929_ChIP-Seq_TH2_Mouse1.08328235
94TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06440199
95* AR_19668381_ChIP-Seq_PC3_Human1.06228149
96LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05629828
97* TAL1_26923725_Chip-Seq_HPCs_Mouse1.05498680
98AHR_22903824_ChIP-Seq_MCF-7_Human1.05078971
99P53_22387025_ChIP-Seq_ESCs_Mouse1.04468013
100YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03369136
101* JUN_21703547_ChIP-Seq_K562_Human1.03330895
102NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03015607
103STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.02506042
104TP53_22573176_ChIP-Seq_HFKS_Human1.02455284
105SUZ12_27294783_Chip-Seq_NPCs_Mouse1.02413783
106IRF1_19129219_ChIP-ChIP_H3396_Human1.02146448
107RBPJ_22232070_ChIP-Seq_NCS_Mouse1.02003347
108RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.00895220
109VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.00718832
110SOX9_26525672_Chip-Seq_HEART_Mouse1.00703893
111MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00029864
112* TCF4_22108803_ChIP-Seq_LS180_Human0.99825205
113EWS_26573619_Chip-Seq_HEK293_Human0.99032745
114E2F1_18555785_Chip-Seq_ESCs_Mouse0.96789770
115CDX2_19796622_ChIP-Seq_MESCs_Mouse0.96612369
116TP53_18474530_ChIP-ChIP_U2OS_Human0.95233026
117EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.94973260
118EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94358657
119FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93726891
120CMYC_18555785_Chip-Seq_ESCs_Mouse0.92907221
121MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92361799
122MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89822256
123* KDM2B_26808549_Chip-Seq_REH_Human0.89770795

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.23946320
2MP0004859_abnormal_synaptic_plasticity5.12529939
3MP0004270_analgesia3.73320645
4MP0003635_abnormal_synaptic_transmissio3.69308714
5MP0009745_abnormal_behavioral_response3.09692686
6MP0002063_abnormal_learning/memory/cond3.09178909
7MP0001968_abnormal_touch/_nociception2.96255278
8MP0002064_seizures2.85017143
9MP0009046_muscle_twitch2.81785368
10MP0005423_abnormal_somatic_nervous2.75011170
11MP0002572_abnormal_emotion/affect_behav2.68135555
12MP0000778_abnormal_nervous_system2.61430224
13MP0002734_abnormal_mechanical_nocicepti2.60840654
14MP0002736_abnormal_nociception_after2.50801450
15MP0002735_abnormal_chemical_nociception2.50056355
16MP0002272_abnormal_nervous_system2.48577496
17MP0001486_abnormal_startle_reflex2.42924158
18MP0006276_abnormal_autonomic_nervous2.37661248
19MP0002184_abnormal_innervation2.24791306
20MP0001529_abnormal_vocalization2.21845357
21MP0002822_catalepsy2.18481554
22MP0001984_abnormal_olfaction2.06287393
23MP0002067_abnormal_sensory_capabilities2.04217523
24MP0001440_abnormal_grooming_behavior2.03348969
25MP0003787_abnormal_imprinting1.95752899
26MP0001188_hyperpigmentation1.91488886
27MP0002733_abnormal_thermal_nociception1.91086492
28MP0001970_abnormal_pain_threshold1.87620383
29MP0002557_abnormal_social/conspecific_i1.85382202
30MP0001501_abnormal_sleep_pattern1.84782622
31MP0005386_behavior/neurological_phenoty1.74378818
32MP0004924_abnormal_behavior1.74378818
33MP0004811_abnormal_neuron_physiology1.67747902
34MP0000955_abnormal_spinal_cord1.63259477
35MP0001905_abnormal_dopamine_level1.62294669
36MP0008569_lethality_at_weaning1.58700542
37MP0005645_abnormal_hypothalamus_physiol1.56663649
38MP0002882_abnormal_neuron_morphology1.54325831
39MP0002653_abnormal_ependyma_morphology1.53952364
40MP0005646_abnormal_pituitary_gland1.53224590
41MP0005253_abnormal_eye_physiology1.51139172
42MP0004142_abnormal_muscle_tone1.49610703
43MP0004133_heterotaxia1.38480149
44MP0003122_maternal_imprinting1.37700439
45MP0002066_abnormal_motor_capabilities/c1.37362855
46MP0000569_abnormal_digit_pigmentation1.37329777
47MP0003011_delayed_dark_adaptation1.36473852
48MP0003879_abnormal_hair_cell1.33710701
49MP0003329_amyloid_beta_deposits1.32516708
50MP0004858_abnormal_nervous_system1.32279074
51MP0005394_taste/olfaction_phenotype1.31457047
52MP0005499_abnormal_olfactory_system1.31457047
53MP0003890_abnormal_embryonic-extraembry1.29744858
54MP0004742_abnormal_vestibular_system1.28199757
55MP0002152_abnormal_brain_morphology1.25745143
56MP0004885_abnormal_endolymph1.22339056
57MP0000631_abnormal_neuroendocrine_gland1.16521631
58MP0009780_abnormal_chondrocyte_physiolo1.15741296
59MP0001502_abnormal_circadian_rhythm1.12673200
60MP0002751_abnormal_autonomic_nervous1.07234182
61MP0002752_abnormal_somatic_nervous1.07031485
62MP0006292_abnormal_olfactory_placode1.06676472
63MP0005187_abnormal_penis_morphology1.05189274
64MP0001485_abnormal_pinna_reflex1.04448067
65MP0005171_absent_coat_pigmentation1.04443228
66MP0008789_abnormal_olfactory_epithelium1.04006829
67MP0001963_abnormal_hearing_physiology1.02804203
68MP0005409_darkened_coat_color1.02127867
69MP0000751_myopathy1.00580918
70MP0010386_abnormal_urinary_bladder1.00525886
71MP0002876_abnormal_thyroid_physiology0.97263028
72MP0002909_abnormal_adrenal_gland0.96933493
73MP0003633_abnormal_nervous_system0.96667976
74MP0005551_abnormal_eye_electrophysiolog0.95850560
75MP0002229_neurodegeneration0.95839938
76MP0003631_nervous_system_phenotype0.94208851
77MP0000049_abnormal_middle_ear0.91971808
78MP0000015_abnormal_ear_pigmentation0.91119305
79MP0005195_abnormal_posterior_eye0.90945420
80MP0002069_abnormal_eating/drinking_beha0.89428501
81MP0003121_genomic_imprinting0.86902120
82MP0004145_abnormal_muscle_electrophysio0.86509399
83MP0003861_abnormal_nervous_system0.86199937
84MP0000026_abnormal_inner_ear0.85985850
85MP0003119_abnormal_digestive_system0.85942116
86MP0003634_abnormal_glial_cell0.85332765
87MP0002638_abnormal_pupillary_reflex0.84605536
88MP0002233_abnormal_nose_morphology0.84116174
89MP0004085_abnormal_heartbeat0.80629229
90MP0002102_abnormal_ear_morphology0.80624772
91MP0000647_abnormal_sebaceous_gland0.79276461
92MP0002938_white_spotting0.78159037
93MP0003632_abnormal_nervous_system0.76864347
94MP0000920_abnormal_myelination0.76664138
95MP0002090_abnormal_vision0.75786268
96MP0003137_abnormal_impulse_conducting0.75369665
97MP0005391_vision/eye_phenotype0.75042719
98MP0003937_abnormal_limbs/digits/tail_de0.74682322
99MP0001177_atelectasis0.74537438
100MP0004043_abnormal_pH_regulation0.73815137
101MP0001986_abnormal_taste_sensitivity0.72733289
102MP0003938_abnormal_ear_development0.71188312
103MP0000566_synostosis0.70829117
104MP0001664_abnormal_digestion0.70650375
105MP0001293_anophthalmia0.67064766
106MP0008872_abnormal_physiological_respon0.66098300
107MP0001943_abnormal_respiration0.65584199
108MP0003123_paternal_imprinting0.65011247
109MP0002837_dystrophic_cardiac_calcinosis0.64272592
110MP0003195_calcinosis0.63835304
111MP0000516_abnormal_urinary_system0.63465012
112MP0006072_abnormal_retinal_apoptosis0.62206738
113MP0001299_abnormal_eye_distance/0.60274956
114MP0002234_abnormal_pharynx_morphology0.60246162
115MP0010770_preweaning_lethality0.57855239
116MP0002082_postnatal_lethality0.57855239
117MP0003136_yellow_coat_color0.57295840
118MP0010769_abnormal_survival0.55981451
119MP0004215_abnormal_myocardial_fiber0.55860988
120MP0008877_abnormal_DNA_methylation0.54686656
121MP0008874_decreased_physiological_sensi0.54007916

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.69985015
2Myokymia (HP:0002411)5.34261817
3Epileptic encephalopathy (HP:0200134)4.86742730
4Focal seizures (HP:0007359)4.81086718
5Hyperventilation (HP:0002883)4.53602224
6Atonic seizures (HP:0010819)4.43144998
7Febrile seizures (HP:0002373)4.27037562
8Broad-based gait (HP:0002136)3.93058224
9Progressive cerebellar ataxia (HP:0002073)3.81661740
10Visual hallucinations (HP:0002367)3.55875361
11Absence seizures (HP:0002121)3.55185974
12Dialeptic seizures (HP:0011146)3.28803695
13True hermaphroditism (HP:0010459)3.17995067
14Generalized tonic-clonic seizures (HP:0002069)3.14065897
15Abnormality of midbrain morphology (HP:0002418)3.11113880
16Molar tooth sign on MRI (HP:0002419)3.11113880
17Limb dystonia (HP:0002451)3.10232842
18Excessive salivation (HP:0003781)3.09202389
19Drooling (HP:0002307)3.09202389
20Pancreatic fibrosis (HP:0100732)3.03706179
21Amblyopia (HP:0000646)3.01374022
22Abnormality of the corticospinal tract (HP:0002492)2.99968491
23Gaze-evoked nystagmus (HP:0000640)2.98772118
24Gait imbalance (HP:0002141)2.94602969
25Pancreatic cysts (HP:0001737)2.92594815
26Abnormal hair whorl (HP:0010721)2.87339902
27Supranuclear gaze palsy (HP:0000605)2.84136404
28Pendular nystagmus (HP:0012043)2.81824288
29Truncal ataxia (HP:0002078)2.79126295
30Ankle clonus (HP:0011448)2.78760921
31Poor eye contact (HP:0000817)2.75267587
32Nephronophthisis (HP:0000090)2.74814207
33Action tremor (HP:0002345)2.73915056
34Protruding tongue (HP:0010808)2.73119156
35Progressive inability to walk (HP:0002505)2.71303867
36Impaired vibration sensation in the lower limbs (HP:0002166)2.71051863
37Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.69722783
38Degeneration of the lateral corticospinal tracts (HP:0002314)2.69722783
39Absent speech (HP:0001344)2.67467929
40Epileptiform EEG discharges (HP:0011182)2.62591027
41Insidious onset (HP:0003587)2.62351471
42Termporal pattern (HP:0011008)2.62351471
43Abnormal eating behavior (HP:0100738)2.62259032
44Medial flaring of the eyebrow (HP:0010747)2.57827125
45Polyphagia (HP:0002591)2.57266362
46Pachygyria (HP:0001302)2.54617748
47Spastic gait (HP:0002064)2.51795624
48Chronic hepatic failure (HP:0100626)2.48109916
49EEG with generalized epileptiform discharges (HP:0011198)2.48108285
50Congenital primary aphakia (HP:0007707)2.42799375
51Impaired social interactions (HP:0000735)2.39633895
52Abnormal social behavior (HP:0012433)2.39633895
53Aplasia/Hypoplasia of the brainstem (HP:0007362)2.38451500
54Hypoplasia of the brainstem (HP:0002365)2.38451500
55Anxiety (HP:0000739)2.37785569
56Urinary bladder sphincter dysfunction (HP:0002839)2.37623184
57Hepatoblastoma (HP:0002884)2.35874133
58Hypsarrhythmia (HP:0002521)2.34840376
59Dysdiadochokinesis (HP:0002075)2.33392641
60Intestinal atresia (HP:0011100)2.32698482
61Dysmetria (HP:0001310)2.32267923
62Inability to walk (HP:0002540)2.31259241
63Nephrogenic diabetes insipidus (HP:0009806)2.31067151
64Type II lissencephaly (HP:0007260)2.30871127
65Pheochromocytoma (HP:0002666)2.30833864
66Depression (HP:0000716)2.30781065
67Urinary urgency (HP:0000012)2.30761233
68Cortical dysplasia (HP:0002539)2.30013197
69Abolished electroretinogram (ERG) (HP:0000550)2.27919154
70Mutism (HP:0002300)2.27192231
71Scanning speech (HP:0002168)2.26135632
72Specific learning disability (HP:0001328)2.26068225
73Esotropia (HP:0000565)2.21108313
74Spastic tetraplegia (HP:0002510)2.20907512
75Genital tract atresia (HP:0001827)2.14875750
76Blue irides (HP:0000635)2.14592468
77Stereotypic behavior (HP:0000733)2.14298855
78Amyotrophic lateral sclerosis (HP:0007354)2.14193232
79Neurofibrillary tangles (HP:0002185)2.13767022
80Akinesia (HP:0002304)2.13418927
81Cerebral inclusion bodies (HP:0100314)2.12802206
82Neuroendocrine neoplasm (HP:0100634)2.12211400
83Retinal dysplasia (HP:0007973)2.11332960
84Abnormality of the renal medulla (HP:0100957)2.10339927
85Lissencephaly (HP:0001339)2.07629170
86Agitation (HP:0000713)2.07150736
87Thickened helices (HP:0000391)2.06944215
88Abnormality of salivation (HP:0100755)2.06739001
89Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.06720584
90Torticollis (HP:0000473)2.05479686
91Optic nerve hypoplasia (HP:0000609)2.05109100
92Hemiparesis (HP:0001269)2.04749903
93Vaginal atresia (HP:0000148)2.04683459
94Postaxial hand polydactyly (HP:0001162)2.04172856
95Fetal akinesia sequence (HP:0001989)2.04170190
96Sleep apnea (HP:0010535)2.03226323
97Narrow forehead (HP:0000341)2.02687880
98Diplopia (HP:0000651)2.02372896
99Abnormality of binocular vision (HP:0011514)2.02372896
100Abnormality of the lower motor neuron (HP:0002366)2.01490436
101Focal dystonia (HP:0004373)2.01367973
102Oligodactyly (hands) (HP:0001180)2.00957851
103Split foot (HP:0001839)2.00257299
104Lower limb muscle weakness (HP:0007340)1.99987277
105Poor coordination (HP:0002370)1.98701965
106Gastroesophageal reflux (HP:0002020)1.98216119
107Anencephaly (HP:0002323)1.95180899
108Genetic anticipation (HP:0003743)1.94830659
109Sclerocornea (HP:0000647)1.92639073
110Poor suck (HP:0002033)1.92464826
111Shoulder girdle muscle weakness (HP:0003547)1.90854885
112Cystic liver disease (HP:0006706)1.87867994
113Exotropia (HP:0000577)1.87267780
114Narrow nasal bridge (HP:0000446)1.87229080
115Impaired smooth pursuit (HP:0007772)1.86214600
116Fair hair (HP:0002286)1.85810473
117Failure to thrive in infancy (HP:0001531)1.85424749
118Abnormality of the labia minora (HP:0012880)1.84950671
119Colon cancer (HP:0003003)1.84482731
120Hypoplasia of the corpus callosum (HP:0002079)1.84371066
121Volvulus (HP:0002580)1.83955617
122Megalencephaly (HP:0001355)1.83600356
123Status epilepticus (HP:0002133)1.83357107
124Hip dysplasia (HP:0001385)1.82375505
125Craniofacial dystonia (HP:0012179)1.80853680
126Postaxial foot polydactyly (HP:0001830)1.79460761
127Septo-optic dysplasia (HP:0100842)1.78957406
128Scrotal hypoplasia (HP:0000046)1.78871557
129Gait ataxia (HP:0002066)1.78500732
130Dynein arm defect of respiratory motile cilia (HP:0012255)1.77517473
131Absent/shortened dynein arms (HP:0200106)1.77517473
132Inappropriate behavior (HP:0000719)1.77437191
133Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.77069409
134Broad foot (HP:0001769)1.75444527
135Impaired vibratory sensation (HP:0002495)1.75132911
136Delusions (HP:0000746)1.75121573
137Generalized myoclonic seizures (HP:0002123)1.72791821
138Renal hypoplasia (HP:0000089)1.72671860
139Labial hypoplasia (HP:0000066)1.72228898
140Hemiplegia (HP:0002301)1.69581732
141Intellectual disability, severe (HP:0010864)1.66388633
142Micropenis (HP:0000054)1.65986681
143Epidermoid cyst (HP:0200040)1.65811417
144Muscular hypotonia of the trunk (HP:0008936)1.64466048
145Hypothermia (HP:0002045)1.62349557

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.94265419
2MARK14.06189399
3NTRK33.66727505
4EPHA43.49174465
5MAP2K73.20953132
6MAP3K42.99259139
7FRK2.46956445
8MAP4K22.40405000
9NTRK22.39909207
10MINK12.39674536
11MAPK132.27590192
12TNIK2.26327128
13MAP3K92.19682346
14DAPK22.10904282
15MAP3K122.09400226
16PINK11.95616382
17CDK191.83090751
18PNCK1.70428390
19PLK21.70129396
20MAP2K41.68773087
21SIK31.67776143
22KSR11.67393601
23TRIM281.61079915
24BCR1.46155363
25DAPK11.39998095
26CDK51.38636907
27DYRK21.38174781
28UHMK11.35812020
29PAK61.33981903
30SGK2231.33827995
31SGK4941.33827995
32EPHA31.33094618
33OXSR11.32108598
34PRPF4B1.31027889
35SIK21.27018820
36GRK51.22288268
37NTRK11.18954629
38PRKCG1.18794823
39RIPK41.16300330
40SGK21.15055870
41CSNK1G21.12831305
42ERBB31.12821679
43INSRR1.12467536
44CAMK2A1.06924573
45NUAK11.05700227
46PHKG21.04933411
47PHKG11.04933411
48MKNK21.04031064
49CAMK2B1.03543396
50AKT31.02310232
51CDK180.93573109
52DYRK30.90944285
53GRK10.89391893
54FES0.88874132
55PRKD30.86384535
56CDK140.84527532
57DYRK1A0.84165651
58CDK150.83960869
59STK390.81714561
60BMPR20.81213001
61CSNK1G30.80568223
62MUSK0.77486129
63KSR20.75320215
64CAMKK10.73509451
65CDK11A0.73109398
66ARAF0.73019875
67CCNB10.71872006
68CAMKK20.71564274
69MKNK10.69926055
70PRKCE0.68066884
71EPHB20.67550672
72FGR0.67512151
73PKN10.67486796
74YES10.67450261
75ZAK0.67273124
76SGK30.66113770
77NME10.65826370
78TYRO30.65369894
79WNK30.62954641
80BCKDK0.62022747
81FGFR20.61956103
82ROCK20.60840342
83STK110.60806035
84MAP3K60.60181681
85MARK20.60081290
86LIMK10.59464301
87CSNK1A1L0.58584756
88SRPK10.56726049
89BMPR1B0.56154545
90SGK10.55722372
91ACVR1B0.55167253
92CSNK1A10.54623075
93CAMK2D0.53431948
94PTK2B0.53085593
95VRK10.52548236
96FER0.52250640
97PAK30.51997217
98ADRBK20.51924506
99TAOK30.50553393
100CAMK10.50071338
101PRKCZ0.49464087
102RPS6KA40.47578666
103WNK40.47445318
104CSNK1D0.46906616
105CAMK2G0.45920105
106RPS6KA20.45274848
107CSNK1G10.44537814
108PLK30.43921559
109BRAF0.43883765
110PRKCH0.43762515
111ADRBK10.43328690
112CAMK1G0.43235046
113PRKACB0.43078001
114CSNK1E0.42626007
115RET0.40924722
116STK160.38363918
117CDK30.36319333
118CAMK40.35751685
119PRKACA0.34808435
120TAF10.33957490
121TAOK10.33727731
122PRKG10.32636637
123RPS6KA30.32079155
124ERBB20.31507137
125FYN0.31412507
126MAP2K10.30983734
127PLK40.30717825
128STK38L0.30654260
129GRK70.30273367
130PRKCB0.30153711
131MAPKAPK50.30084369
132LATS20.29722569

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.24065322
2Synaptic vesicle cycle_Homo sapiens_hsa047213.33686726
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.90875325
4Olfactory transduction_Homo sapiens_hsa047402.84554352
5GABAergic synapse_Homo sapiens_hsa047272.77260104
6Glutamatergic synapse_Homo sapiens_hsa047242.70871874
7Circadian entrainment_Homo sapiens_hsa047132.65482924
8Morphine addiction_Homo sapiens_hsa050322.60724349
9Long-term potentiation_Homo sapiens_hsa047202.50464072
10Amphetamine addiction_Homo sapiens_hsa050312.43101911
11Dopaminergic synapse_Homo sapiens_hsa047282.34604497
12Taste transduction_Homo sapiens_hsa047422.20403813
13Serotonergic synapse_Homo sapiens_hsa047262.11864275
14Collecting duct acid secretion_Homo sapiens_hsa049662.08148784
15Steroid biosynthesis_Homo sapiens_hsa001002.06039812
16Salivary secretion_Homo sapiens_hsa049701.87911993
17Cholinergic synapse_Homo sapiens_hsa047251.82812835
18Long-term depression_Homo sapiens_hsa047301.81161225
19Axon guidance_Homo sapiens_hsa043601.76652458
20Insulin secretion_Homo sapiens_hsa049111.71266131
21Protein export_Homo sapiens_hsa030601.66472771
22Renin secretion_Homo sapiens_hsa049241.64068394
23Cocaine addiction_Homo sapiens_hsa050301.62414432
24Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.61998186
25Calcium signaling pathway_Homo sapiens_hsa040201.54094756
26Gastric acid secretion_Homo sapiens_hsa049711.52332106
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.49885078
28Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.46071694
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.45184547
30Oxytocin signaling pathway_Homo sapiens_hsa049211.42774627
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.41083224
32Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.39709958
33Phototransduction_Homo sapiens_hsa047441.37993595
34Oxidative phosphorylation_Homo sapiens_hsa001901.36008417
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.34833725
36Gap junction_Homo sapiens_hsa045401.33927069
37Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.33333707
38Vibrio cholerae infection_Homo sapiens_hsa051101.27297356
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25696120
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.24201596
41GnRH signaling pathway_Homo sapiens_hsa049121.22458110
42Alzheimers disease_Homo sapiens_hsa050101.19549866
43Maturity onset diabetes of the young_Homo sapiens_hsa049501.19296358
44ErbB signaling pathway_Homo sapiens_hsa040121.19078083
45Primary bile acid biosynthesis_Homo sapiens_hsa001201.17537177
46Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.15019716
47cAMP signaling pathway_Homo sapiens_hsa040241.11129899
48Cardiac muscle contraction_Homo sapiens_hsa042601.09126331
49Propanoate metabolism_Homo sapiens_hsa006401.09048593
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.06944494
51Selenocompound metabolism_Homo sapiens_hsa004501.06341941
52Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.05606568
53Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.05030276
54Melanogenesis_Homo sapiens_hsa049161.03923707
55Basal transcription factors_Homo sapiens_hsa030221.02781507
56Parkinsons disease_Homo sapiens_hsa050121.01444564
57Glioma_Homo sapiens_hsa052140.93442739
58Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.91902737
59Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91484665
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91050802
61Oocyte meiosis_Homo sapiens_hsa041140.89813288
62Tryptophan metabolism_Homo sapiens_hsa003800.89140074
63Nitrogen metabolism_Homo sapiens_hsa009100.88234093
64Estrogen signaling pathway_Homo sapiens_hsa049150.87158960
65cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83228082
66Type II diabetes mellitus_Homo sapiens_hsa049300.83090490
67Linoleic acid metabolism_Homo sapiens_hsa005910.82716427
68Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.79122292
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.78990932
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.78108104
71Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.78028631
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.76604690
73Alcoholism_Homo sapiens_hsa050340.75590313
74Huntingtons disease_Homo sapiens_hsa050160.75115084
75RNA polymerase_Homo sapiens_hsa030200.74125983
76Peroxisome_Homo sapiens_hsa041460.73714062
77Fatty acid elongation_Homo sapiens_hsa000620.67250420
78Fanconi anemia pathway_Homo sapiens_hsa034600.65853847
79Ras signaling pathway_Homo sapiens_hsa040140.64846178
80Choline metabolism in cancer_Homo sapiens_hsa052310.64175135
81MAPK signaling pathway_Homo sapiens_hsa040100.63927021
82Wnt signaling pathway_Homo sapiens_hsa043100.63010447
83Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61553981
84beta-Alanine metabolism_Homo sapiens_hsa004100.61287391
85RNA degradation_Homo sapiens_hsa030180.58296373
86Phospholipase D signaling pathway_Homo sapiens_hsa040720.57646958
87Pancreatic secretion_Homo sapiens_hsa049720.56783632
88Fatty acid metabolism_Homo sapiens_hsa012120.56680942
89Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55521141
90Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55399560
91Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54728847
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.53115149
93Basal cell carcinoma_Homo sapiens_hsa052170.52219631
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.52140769
95Colorectal cancer_Homo sapiens_hsa052100.50115436
96Dorso-ventral axis formation_Homo sapiens_hsa043200.49768103
97Endometrial cancer_Homo sapiens_hsa052130.47763108
98Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47587102
99Sphingolipid signaling pathway_Homo sapiens_hsa040710.46657876
100Dilated cardiomyopathy_Homo sapiens_hsa054140.46204217
101Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.44319970
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43972394
103Rap1 signaling pathway_Homo sapiens_hsa040150.43724165
104Renal cell carcinoma_Homo sapiens_hsa052110.41674697
105Phagosome_Homo sapiens_hsa041450.41457682
106Rheumatoid arthritis_Homo sapiens_hsa053230.40647404
107Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.40554501
108Hedgehog signaling pathway_Homo sapiens_hsa043400.40372222
109Hippo signaling pathway_Homo sapiens_hsa043900.40328385
110Thyroid hormone synthesis_Homo sapiens_hsa049180.39131577
111Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38082019
112Ether lipid metabolism_Homo sapiens_hsa005650.36327482
113VEGF signaling pathway_Homo sapiens_hsa043700.36219201
114Circadian rhythm_Homo sapiens_hsa047100.35326629
115Ovarian steroidogenesis_Homo sapiens_hsa049130.33931545
116Endocytosis_Homo sapiens_hsa041440.33927702
117Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.33517295
118Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.32986381
119Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32420205
120Inositol phosphate metabolism_Homo sapiens_hsa005620.32404305
121Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.31925347
122Type I diabetes mellitus_Homo sapiens_hsa049400.31721700
123Butanoate metabolism_Homo sapiens_hsa006500.31342324
124Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.31089491
125Glucagon signaling pathway_Homo sapiens_hsa049220.30374338
126Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.29724323
127ABC transporters_Homo sapiens_hsa020100.28653459
128Metabolic pathways_Homo sapiens_hsa011000.28619650
129African trypanosomiasis_Homo sapiens_hsa051430.28549818
130Thyroid hormone signaling pathway_Homo sapiens_hsa049190.28274051
131Fatty acid biosynthesis_Homo sapiens_hsa000610.26152777
132Melanoma_Homo sapiens_hsa052180.25612282
133Non-homologous end-joining_Homo sapiens_hsa034500.24805433
134Non-small cell lung cancer_Homo sapiens_hsa052230.24411878
135Carbohydrate digestion and absorption_Homo sapiens_hsa049730.23889743
136Regulation of autophagy_Homo sapiens_hsa041400.22855445
137Histidine metabolism_Homo sapiens_hsa003400.22231780

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