

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of cell killing (GO:0031342) | 7.15473308 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 7.15473308 |
| 3 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.73352270 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.25552478 |
| 5 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.69360139 |
| 6 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.62911326 |
| 7 | positive regulation by symbiont of host defense response (GO:0052509) | 5.53332855 |
| 8 | modulation by symbiont of host defense response (GO:0052031) | 5.53332855 |
| 9 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.53332855 |
| 10 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.53332855 |
| 11 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.53332855 |
| 12 | modulation by symbiont of host immune response (GO:0052553) | 5.53332855 |
| 13 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.49323760 |
| 14 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.08522348 |
| 15 | neutrophil activation involved in immune response (GO:0002283) | 5.04239352 |
| 16 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.92826188 |
| 17 | response to interleukin-15 (GO:0070672) | 4.88342880 |
| 18 | detection of other organism (GO:0098543) | 4.87262963 |
| 19 | cellular response to interleukin-15 (GO:0071350) | 4.73818233 |
| 20 | macrophage activation involved in immune response (GO:0002281) | 4.64334552 |
| 21 | regulation of gamma-delta T cell activation (GO:0046643) | 4.64188501 |
| 22 | detection of bacterium (GO:0016045) | 4.59552461 |
| 23 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.57611024 |
| 24 | leukocyte aggregation (GO:0070486) | 4.51026651 |
| 25 | detection of molecule of bacterial origin (GO:0032490) | 4.44953308 |
| 26 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.38490742 |
| 27 | detection of external biotic stimulus (GO:0098581) | 4.36306529 |
| 28 | cellular extravasation (GO:0045123) | 4.18374077 |
| 29 | negative regulation of T cell mediated immunity (GO:0002710) | 4.18351419 |
| 30 | neutrophil activation (GO:0042119) | 4.17467429 |
| 31 | negative regulation of interleukin-12 production (GO:0032695) | 4.17299404 |
| 32 | microglial cell activation (GO:0001774) | 4.12910802 |
| 33 | response to peptidoglycan (GO:0032494) | 4.12510463 |
| 34 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.98877863 |
| 35 | negative T cell selection (GO:0043383) | 3.98490460 |
| 36 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.98340145 |
| 37 | respiratory burst (GO:0045730) | 3.97370881 |
| 38 | negative thymic T cell selection (GO:0045060) | 3.91170308 |
| 39 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.89957077 |
| 40 | immunoglobulin mediated immune response (GO:0016064) | 3.87929607 |
| 41 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.86920824 |
| 42 | detection of biotic stimulus (GO:0009595) | 3.84568482 |
| 43 | response to host immune response (GO:0052572) | 3.82392722 |
| 44 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.82392722 |
| 45 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.82086428 |
| 46 | granulocyte activation (GO:0036230) | 3.77907119 |
| 47 | myeloid cell activation involved in immune response (GO:0002275) | 3.73037568 |
| 48 | positive thymic T cell selection (GO:0045059) | 3.71528236 |
| 49 | neutrophil mediated immunity (GO:0002446) | 3.71371931 |
| 50 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.69420694 |
| 51 | macrophage activation (GO:0042116) | 3.63281551 |
| 52 | B cell receptor signaling pathway (GO:0050853) | 3.61174814 |
| 53 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.53341438 |
| 54 | regulation of mast cell degranulation (GO:0043304) | 3.49261407 |
| 55 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.49207316 |
| 56 | response to host (GO:0075136) | 3.49207316 |
| 57 | response to host defenses (GO:0052200) | 3.49207316 |
| 58 | regulation of B cell differentiation (GO:0045577) | 3.48925688 |
| 59 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.48224947 |
| 60 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.46309589 |
| 61 | positive regulation of mast cell activation (GO:0033005) | 3.44238306 |
| 62 | positive T cell selection (GO:0043368) | 3.43200270 |
| 63 | regulation of T cell tolerance induction (GO:0002664) | 3.40323959 |
| 64 | leukocyte degranulation (GO:0043299) | 3.39380990 |
| 65 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.39308042 |
| 66 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.37106083 |
| 67 | regulation of tolerance induction (GO:0002643) | 3.35849350 |
| 68 | regulation of regulatory T cell differentiation (GO:0045589) | 3.34856084 |
| 69 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.34150595 |
| 70 | cellular response to type I interferon (GO:0071357) | 3.31643182 |
| 71 | type I interferon signaling pathway (GO:0060337) | 3.31643182 |
| 72 | activated T cell proliferation (GO:0050798) | 3.30932369 |
| 73 | response to type I interferon (GO:0034340) | 3.29215460 |
| 74 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.25593829 |
| 75 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.25593829 |
| 76 | myeloid leukocyte mediated immunity (GO:0002444) | 3.24066320 |
| 77 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.23540340 |
| 78 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.23304106 |
| 79 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.21290122 |
| 80 | positive regulation of B cell differentiation (GO:0045579) | 3.20871774 |
| 81 | regulation of mast cell activation (GO:0033003) | 3.20599067 |
| 82 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.18987687 |
| 83 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.18987687 |
| 84 | T cell selection (GO:0045058) | 3.18964218 |
| 85 | T cell migration (GO:0072678) | 3.15322028 |
| 86 | response to muramyl dipeptide (GO:0032495) | 3.14112340 |
| 87 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.13837493 |
| 88 | dendritic cell migration (GO:0036336) | 3.13753266 |
| 89 | B cell mediated immunity (GO:0019724) | 3.12357268 |
| 90 | defense response to protozoan (GO:0042832) | 3.12277597 |
| 91 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.11145442 |
| 92 | dendritic cell chemotaxis (GO:0002407) | 3.06643964 |
| 93 | mast cell activation (GO:0045576) | 3.05422562 |
| 94 | tolerance induction (GO:0002507) | 3.05342467 |
| 95 | regulation of leukocyte degranulation (GO:0043300) | 3.03509281 |
| 96 | negative regulation of adaptive immune response (GO:0002820) | 3.02231960 |
| 97 | negative regulation of innate immune response (GO:0045824) | 2.98872282 |
| 98 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.96774353 |
| 99 | thymic T cell selection (GO:0045061) | 2.94192302 |
| 100 | positive regulation of tolerance induction (GO:0002645) | 2.92229560 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.05640797 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.79978269 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.65958790 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.50674209 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.39575018 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.78337372 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.30465271 |
| 8 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.24124420 |
| 9 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.23582927 |
| 10 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.18339540 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.11502944 |
| 12 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.95140311 |
| 13 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.82160040 |
| 14 | MYB_26560356_Chip-Seq_TH2_Human | 2.74223064 |
| 15 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.71649928 |
| 16 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.69184610 |
| 17 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.62154821 |
| 18 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.53773228 |
| 19 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.53648638 |
| 20 | SPI1_23127762_ChIP-Seq_K562_Human | 2.50655806 |
| 21 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.42065106 |
| 22 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.38960953 |
| 23 | MAF_26560356_Chip-Seq_TH1_Human | 2.38351565 |
| 24 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.34698378 |
| 25 | MYB_26560356_Chip-Seq_TH1_Human | 2.22980134 |
| 26 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.20541723 |
| 27 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.18514357 |
| 28 | UTX_26944678_Chip-Seq_JUKART_Human | 2.16108316 |
| 29 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.14959012 |
| 30 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.08241490 |
| 31 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.00486485 |
| 32 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.92102368 |
| 33 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.87600074 |
| 34 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.86448858 |
| 35 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.85455457 |
| 36 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.84733194 |
| 37 | MYC_22102868_ChIP-Seq_BL_Human | 1.81093337 |
| 38 | MAF_26560356_Chip-Seq_TH2_Human | 1.75784552 |
| 39 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.72981481 |
| 40 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.72322483 |
| 41 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.63502403 |
| 42 | GATA3_26560356_Chip-Seq_TH2_Human | 1.63247226 |
| 43 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.63026317 |
| 44 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.61210132 |
| 45 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.59740364 |
| 46 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.55909864 |
| 47 | GATA1_22025678_ChIP-Seq_K562_Human | 1.52804254 |
| 48 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.52179097 |
| 49 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.48709356 |
| 50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.48362103 |
| 51 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.48344121 |
| 52 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45912201 |
| 53 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.41472310 |
| 54 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.39346881 |
| 55 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.39098272 |
| 56 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.37992855 |
| 57 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.37005377 |
| 58 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.34715168 |
| 59 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.34100138 |
| 60 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.29275881 |
| 61 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.29185242 |
| 62 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.29025716 |
| 63 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.28186365 |
| 64 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.26826999 |
| 65 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.26327772 |
| 66 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.24279076 |
| 67 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.23363066 |
| 68 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.21320747 |
| 69 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.20098022 |
| 70 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.17335776 |
| 71 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.16843140 |
| 72 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.13511550 |
| 73 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.13265345 |
| 74 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.11938649 |
| 75 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11741590 |
| 76 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.11341040 |
| 77 | GATA1_19941826_ChIP-Seq_K562_Human | 1.10696852 |
| 78 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.07365558 |
| 79 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06204284 |
| 80 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.04598519 |
| 81 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.01717122 |
| 82 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.00960335 |
| 83 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.97467914 |
| 84 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.95506773 |
| 85 | GATA2_19941826_ChIP-Seq_K562_Human | 0.93653761 |
| 86 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.92835857 |
| 87 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.90393219 |
| 88 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.90158774 |
| 89 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.87164632 |
| 90 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85591859 |
| 91 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.83994891 |
| 92 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.82700260 |
| 93 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.81294066 |
| 94 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.81273566 |
| 95 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.80880881 |
| 96 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.77525505 |
| 97 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75802231 |
| 98 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.73756362 |
| 99 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.73018838 |
| 100 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.71964683 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 5.09137833 |
| 2 | MP0001835_abnormal_antigen_presentation | 4.12859001 |
| 3 | MP0003436_decreased_susceptibility_to | 4.08521949 |
| 4 | MP0005671_abnormal_response_to | 3.62198736 |
| 5 | MP0003303_peritoneal_inflammation | 3.17644972 |
| 6 | MP0002419_abnormal_innate_immunity | 3.11107286 |
| 7 | MP0001800_abnormal_humoral_immune | 3.10419982 |
| 8 | MP0009785_altered_susceptibility_to | 3.00410597 |
| 9 | MP0005000_abnormal_immune_tolerance | 2.97146038 |
| 10 | MP0000685_abnormal_immune_system | 2.93247565 |
| 11 | MP0005025_abnormal_response_to | 2.93222253 |
| 12 | MP0002723_abnormal_immune_serum | 2.75771530 |
| 13 | MP0005387_immune_system_phenotype | 2.75740270 |
| 14 | MP0001790_abnormal_immune_system | 2.75740270 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.67567640 |
| 16 | MP0003763_abnormal_thymus_physiology | 2.67322401 |
| 17 | MP0001819_abnormal_immune_cell | 2.64936549 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.60891474 |
| 19 | MP0006082_CNS_inflammation | 2.53355235 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 2.35801073 |
| 21 | MP0003300_gastrointestinal_ulcer | 2.19971064 |
| 22 | MP0002405_respiratory_system_inflammati | 2.13666755 |
| 23 | MP0008260_abnormal_autophagy | 2.10809101 |
| 24 | MP0001533_abnormal_skeleton_physiology | 2.10181097 |
| 25 | MP0002398_abnormal_bone_marrow | 2.09215294 |
| 26 | MP0000716_abnormal_immune_system | 2.03409533 |
| 27 | MP0003191_abnormal_cellular_cholesterol | 2.00387333 |
| 28 | MP0005464_abnormal_platelet_physiology | 1.99855005 |
| 29 | MP0003866_abnormal_defecation | 1.91619718 |
| 30 | MP0010155_abnormal_intestine_physiology | 1.84959065 |
| 31 | MP0001845_abnormal_inflammatory_respons | 1.79393944 |
| 32 | MP0000689_abnormal_spleen_morphology | 1.74802634 |
| 33 | MP0004381_abnormal_hair_follicle | 1.74625106 |
| 34 | MP0002722_abnormal_immune_system | 1.73174237 |
| 35 | MP0004947_skin_inflammation | 1.71885405 |
| 36 | MP0003828_pulmonary_edema | 1.70764691 |
| 37 | MP0000465_gastrointestinal_hemorrhage | 1.69810026 |
| 38 | MP0003172_abnormal_lysosome_physiology | 1.67879427 |
| 39 | MP0002132_abnormal_respiratory_system | 1.66911968 |
| 40 | MP0009333_abnormal_splenocyte_physiolog | 1.65230146 |
| 41 | MP0000703_abnormal_thymus_morphology | 1.64872474 |
| 42 | MP0002429_abnormal_blood_cell | 1.59673178 |
| 43 | MP0002396_abnormal_hematopoietic_system | 1.59508368 |
| 44 | MP0002277_abnormal_respiratory_mucosa | 1.47329354 |
| 45 | MP0009764_decreased_sensitivity_to | 1.45748399 |
| 46 | MP0002166_altered_tumor_susceptibility | 1.44879222 |
| 47 | MP0003183_abnormal_peptide_metabolism | 1.44475282 |
| 48 | MP0008469_abnormal_protein_level | 1.42031940 |
| 49 | MP0004883_abnormal_blood_vessel | 1.41831946 |
| 50 | MP0005310_abnormal_salivary_gland | 1.40794539 |
| 51 | MP0000569_abnormal_digit_pigmentation | 1.38334061 |
| 52 | MP0005451_abnormal_body_composition | 1.37990327 |
| 53 | MP0000858_altered_metastatic_potential | 1.34593093 |
| 54 | MP0005075_abnormal_melanosome_morpholog | 1.31116890 |
| 55 | MP0009278_abnormal_bone_marrow | 1.29370947 |
| 56 | MP0001851_eye_inflammation | 1.25402595 |
| 57 | MP0002998_abnormal_bone_remodeling | 1.20073518 |
| 58 | MP0005164_abnormal_response_to | 1.06613348 |
| 59 | MP0003075_altered_response_to | 1.06125788 |
| 60 | MP0005397_hematopoietic_system_phenotyp | 1.04925459 |
| 61 | MP0001545_abnormal_hematopoietic_system | 1.04925459 |
| 62 | MP0003690_abnormal_glial_cell | 1.03155055 |
| 63 | MP0000015_abnormal_ear_pigmentation | 0.97427911 |
| 64 | MP0001853_heart_inflammation | 0.95361102 |
| 65 | MP0002006_tumorigenesis | 0.93164324 |
| 66 | MP0005166_decreased_susceptibility_to | 0.91819803 |
| 67 | MP0009763_increased_sensitivity_to | 0.90299584 |
| 68 | MP0003448_altered_tumor_morphology | 0.89892777 |
| 69 | MP0003656_abnormal_erythrocyte_physiolo | 0.85884739 |
| 70 | MP0005058_abnormal_lysosome_morphology | 0.83490215 |
| 71 | MP0001873_stomach_inflammation | 0.81655314 |
| 72 | MP0003045_fibrosis | 0.80417598 |
| 73 | MP0005390_skeleton_phenotype | 0.80302137 |
| 74 | MP0000604_amyloidosis | 0.80211083 |
| 75 | MP0004510_myositis | 0.78649491 |
| 76 | MP0001663_abnormal_digestive_system | 0.77481709 |
| 77 | MP0002933_joint_inflammation | 0.76992778 |
| 78 | MP0003806_abnormal_nucleotide_metabolis | 0.74946172 |
| 79 | MP0005174_abnormal_tail_pigmentation | 0.72590012 |
| 80 | MP0009765_abnormal_xenobiotic_induced | 0.71698066 |
| 81 | MP0001986_abnormal_taste_sensitivity | 0.71076583 |
| 82 | MP0000343_altered_response_to | 0.69474384 |
| 83 | MP0004808_abnormal_hematopoietic_stem | 0.68430600 |
| 84 | MP0004130_abnormal_muscle_cell | 0.65855608 |
| 85 | MP0000249_abnormal_blood_vessel | 0.64024887 |
| 86 | MP0003795_abnormal_bone_structure | 0.63930071 |
| 87 | MP0003221_abnormal_cardiomyocyte_apopto | 0.62991591 |
| 88 | MP0005377_hearing/vestibular/ear_phenot | 0.61152331 |
| 89 | MP0003878_abnormal_ear_physiology | 0.61152331 |
| 90 | MP0003787_abnormal_imprinting | 0.60304826 |
| 91 | MP0000490_abnormal_crypts_of | 0.58683213 |
| 92 | MP0003252_abnormal_bile_duct | 0.57599985 |
| 93 | MP0008004_abnormal_stomach_pH | 0.56790983 |
| 94 | MP0008874_decreased_physiological_sensi | 0.56009983 |
| 95 | MP0002019_abnormal_tumor_incidence | 0.55639072 |
| 96 | MP0005388_respiratory_system_phenotype | 0.51232877 |
| 97 | MP0002133_abnormal_respiratory_system | 0.51232877 |
| 98 | MP0005083_abnormal_biliary_tract | 0.51084196 |
| 99 | MP0002138_abnormal_hepatobiliary_system | 0.50275505 |
| 100 | MP0004484_altered_response_of | 0.50139417 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 6.73246562 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 6.08315472 |
| 3 | Recurrent abscess formation (HP:0002722) | 6.04534748 |
| 4 | Myositis (HP:0100614) | 6.01468814 |
| 5 | Orchitis (HP:0100796) | 5.75243209 |
| 6 | Retrobulbar optic neuritis (HP:0100654) | 5.62048527 |
| 7 | Optic neuritis (HP:0100653) | 5.62048527 |
| 8 | Stomatitis (HP:0010280) | 5.03140300 |
| 9 | Abnormality of macrophages (HP:0004311) | 5.00463551 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.90321153 |
| 11 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.81623532 |
| 12 | Gastrointestinal infarctions (HP:0005244) | 4.66762046 |
| 13 | T lymphocytopenia (HP:0005403) | 4.64244963 |
| 14 | Recurrent fungal infections (HP:0002841) | 4.57536343 |
| 15 | Abnormality of T cell number (HP:0011839) | 4.37034597 |
| 16 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.14786887 |
| 17 | Obstructive lung disease (HP:0006536) | 4.12471107 |
| 18 | Chronic obstructive pulmonary disease (HP:0006510) | 4.12471107 |
| 19 | Mediastinal lymphadenopathy (HP:0100721) | 4.12362565 |
| 20 | Recurrent skin infections (HP:0001581) | 4.11702281 |
| 21 | Meningitis (HP:0001287) | 4.10260511 |
| 22 | Keratoconjunctivitis sicca (HP:0001097) | 4.08585229 |
| 23 | Recurrent cutaneous fungal infections (HP:0011370) | 3.92274753 |
| 24 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.92274753 |
| 25 | Encephalitis (HP:0002383) | 3.91737630 |
| 26 | Keratoconjunctivitis (HP:0001096) | 3.82605629 |
| 27 | Vasculitis (HP:0002633) | 3.63225902 |
| 28 | Gingivitis (HP:0000230) | 3.63219995 |
| 29 | Spontaneous hematomas (HP:0007420) | 3.58821217 |
| 30 | Urticaria (HP:0001025) | 3.45181049 |
| 31 | Abnormality of T cells (HP:0002843) | 3.43235857 |
| 32 | Chest pain (HP:0100749) | 3.38054715 |
| 33 | Hemoptysis (HP:0002105) | 3.33370466 |
| 34 | Pulmonary infiltrates (HP:0002113) | 3.29795436 |
| 35 | Leukocytosis (HP:0001974) | 3.25440560 |
| 36 | Hypochromic microcytic anemia (HP:0004840) | 3.25083249 |
| 37 | Increased IgE level (HP:0003212) | 3.22332868 |
| 38 | Arterial thrombosis (HP:0004420) | 3.15527037 |
| 39 | Prolonged bleeding time (HP:0003010) | 3.07316225 |
| 40 | Gingival bleeding (HP:0000225) | 3.07040659 |
| 41 | Recurrent viral infections (HP:0004429) | 3.04454410 |
| 42 | Hypochromic anemia (HP:0001931) | 3.00197239 |
| 43 | Cellulitis (HP:0100658) | 2.92056882 |
| 44 | Anorexia (HP:0002039) | 2.91962536 |
| 45 | Peritonitis (HP:0002586) | 2.91799517 |
| 46 | Episodic fever (HP:0001954) | 2.90153253 |
| 47 | Pulmonary embolism (HP:0002204) | 2.89388441 |
| 48 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.87983712 |
| 49 | Panhypogammaglobulinemia (HP:0003139) | 2.84770989 |
| 50 | Pustule (HP:0200039) | 2.83860551 |
| 51 | Granulocytopenia (HP:0001913) | 2.79346163 |
| 52 | Epistaxis (HP:0000421) | 2.75988728 |
| 53 | Inflammation of the large intestine (HP:0002037) | 2.71847644 |
| 54 | Gangrene (HP:0100758) | 2.63562194 |
| 55 | Increased IgM level (HP:0003496) | 2.63464593 |
| 56 | Gastrointestinal inflammation (HP:0004386) | 2.58403136 |
| 57 | Abnormality of the pleura (HP:0002103) | 2.56689557 |
| 58 | Abnormality of eosinophils (HP:0001879) | 2.54037528 |
| 59 | Eosinophilia (HP:0001880) | 2.53725146 |
| 60 | Abnormality of T cell physiology (HP:0011840) | 2.50536493 |
| 61 | Osteomyelitis (HP:0002754) | 2.47121833 |
| 62 | Amyloidosis (HP:0011034) | 2.46481757 |
| 63 | Lymphopenia (HP:0001888) | 2.35051585 |
| 64 | Sepsis (HP:0100806) | 2.34776718 |
| 65 | Recurrent bronchitis (HP:0002837) | 2.34758781 |
| 66 | Petechiae (HP:0000967) | 2.34351157 |
| 67 | Microcytic anemia (HP:0001935) | 2.31467681 |
| 68 | Glomerulopathy (HP:0100820) | 2.27961538 |
| 69 | Severe combined immunodeficiency (HP:0004430) | 2.26223527 |
| 70 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.23017147 |
| 71 | Abnormality of the peritoneum (HP:0002585) | 2.22333610 |
| 72 | Acute hepatic failure (HP:0006554) | 2.21355289 |
| 73 | Abnormality of the endocardium (HP:0004306) | 2.20758577 |
| 74 | Keratitis (HP:0000491) | 2.19806462 |
| 75 | Vertigo (HP:0002321) | 2.17426674 |
| 76 | IgM deficiency (HP:0002850) | 2.17292855 |
| 77 | Hypergammaglobulinemia (HP:0010702) | 2.16110545 |
| 78 | IgG deficiency (HP:0004315) | 2.14951143 |
| 79 | Colitis (HP:0002583) | 2.13225508 |
| 80 | Agammaglobulinemia (HP:0004432) | 2.12923294 |
| 81 | Slow saccadic eye movements (HP:0000514) | 2.11825698 |
| 82 | Autoimmune hemolytic anemia (HP:0001890) | 2.09964952 |
| 83 | Skin ulcer (HP:0200042) | 2.06494068 |
| 84 | Joint swelling (HP:0001386) | 2.05826298 |
| 85 | Abnormality of the pericardium (HP:0001697) | 2.04510181 |
| 86 | Polyneuropathy (HP:0001271) | 2.03037261 |
| 87 | Acne (HP:0001061) | 1.98784932 |
| 88 | Hepatosplenomegaly (HP:0001433) | 1.96845940 |
| 89 | Chronic otitis media (HP:0000389) | 1.95679922 |
| 90 | Thrombophlebitis (HP:0004418) | 1.91656202 |
| 91 | Skin rash (HP:0000988) | 1.89046874 |
| 92 | Autoimmune thrombocytopenia (HP:0001973) | 1.87171423 |
| 93 | Premature loss of primary teeth (HP:0006323) | 1.86320271 |
| 94 | Purpura (HP:0000979) | 1.84748850 |
| 95 | Chronic diarrhea (HP:0002028) | 1.84439270 |
| 96 | Amaurosis fugax (HP:0100576) | 1.83345396 |
| 97 | Viral hepatitis (HP:0006562) | 1.83188326 |
| 98 | Recurrent pneumonia (HP:0006532) | 1.79744418 |
| 99 | Arthralgia (HP:0002829) | 1.79519313 |
| 100 | Increased cerebral lipofuscin (HP:0011813) | 1.79002456 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.65070951 |
| 2 | MAP4K1 | 3.68642489 |
| 3 | BLK | 3.20186278 |
| 4 | TXK | 2.98287001 |
| 5 | IRAK4 | 2.96333449 |
| 6 | FES | 2.90723591 |
| 7 | CSK | 2.84232890 |
| 8 | GRK6 | 2.77540356 |
| 9 | TYK2 | 2.76850625 |
| 10 | MAP2K3 | 2.59014205 |
| 11 | TAOK3 | 2.41925641 |
| 12 | ERN1 | 2.12902439 |
| 13 | TNK2 | 2.06509343 |
| 14 | ZAP70 | 2.05223921 |
| 15 | JAK3 | 2.01740730 |
| 16 | MAP3K14 | 1.95029665 |
| 17 | BTK | 1.93780276 |
| 18 | EPHB1 | 1.87744727 |
| 19 | SYK | 1.86710234 |
| 20 | IKBKE | 1.85271872 |
| 21 | FGR | 1.84828074 |
| 22 | HCK | 1.76113374 |
| 23 | JAK1 | 1.71161349 |
| 24 | LYN | 1.49315487 |
| 25 | MAP3K3 | 1.48399848 |
| 26 | PRPF4B | 1.45178859 |
| 27 | MAP3K11 | 1.44704052 |
| 28 | TAOK1 | 1.42841016 |
| 29 | JAK2 | 1.41408410 |
| 30 | MAP3K13 | 1.39419974 |
| 31 | LCK | 1.38076260 |
| 32 | KIT | 1.37820846 |
| 33 | ITK | 1.37312852 |
| 34 | BMPR2 | 1.35291504 |
| 35 | TBK1 | 1.33157527 |
| 36 | CSF1R | 1.25954641 |
| 37 | MATK | 1.18872465 |
| 38 | MAP3K1 | 1.17634857 |
| 39 | YES1 | 1.15791306 |
| 40 | KSR2 | 1.13045780 |
| 41 | TEC | 1.10598154 |
| 42 | MARK3 | 1.03182873 |
| 43 | IKBKB | 1.03081154 |
| 44 | TESK2 | 1.00198760 |
| 45 | IRAK1 | 0.97753842 |
| 46 | SIK3 | 0.93988533 |
| 47 | STK10 | 0.88748533 |
| 48 | PDK1 | 0.88164189 |
| 49 | CDK19 | 0.86896689 |
| 50 | MARK2 | 0.85473420 |
| 51 | PTK6 | 0.81897785 |
| 52 | PIK3CG | 0.81258258 |
| 53 | FGFR3 | 0.76639663 |
| 54 | TGFBR2 | 0.76590742 |
| 55 | LRRK2 | 0.76038978 |
| 56 | MAP3K2 | 0.74859062 |
| 57 | FYN | 0.73807992 |
| 58 | PRKCQ | 0.73780179 |
| 59 | MAP3K6 | 0.70981684 |
| 60 | IRAK2 | 0.69814665 |
| 61 | PTK2B | 0.68784848 |
| 62 | EPHA3 | 0.68233099 |
| 63 | PRKD2 | 0.66277287 |
| 64 | PDPK1 | 0.63820010 |
| 65 | FGFR4 | 0.63373113 |
| 66 | CAMKK2 | 0.63274491 |
| 67 | MAP3K7 | 0.62581234 |
| 68 | PIM1 | 0.59314890 |
| 69 | NLK | 0.58088575 |
| 70 | STK11 | 0.57918324 |
| 71 | RAF1 | 0.56722716 |
| 72 | DYRK1B | 0.54990060 |
| 73 | MAPK12 | 0.54215515 |
| 74 | SIK2 | 0.53827673 |
| 75 | TAOK2 | 0.51793598 |
| 76 | MAP2K6 | 0.49476738 |
| 77 | SGK3 | 0.49164465 |
| 78 | MAPK7 | 0.48664896 |
| 79 | MAP3K5 | 0.47039391 |
| 80 | GRK7 | 0.46376003 |
| 81 | CAMKK1 | 0.45101625 |
| 82 | MAP2K4 | 0.44576845 |
| 83 | MAP2K2 | 0.42610620 |
| 84 | STK38 | 0.42491025 |
| 85 | HIPK2 | 0.41731728 |
| 86 | CDC42BPA | 0.41315091 |
| 87 | SGK2 | 0.40535514 |
| 88 | RET | 0.40282525 |
| 89 | MAPKAPK2 | 0.39674903 |
| 90 | KSR1 | 0.39004562 |
| 91 | TRIB3 | 0.38561061 |
| 92 | WNK1 | 0.38482689 |
| 93 | RPS6KL1 | 0.32042427 |
| 94 | RPS6KC1 | 0.32042427 |
| 95 | KDR | 0.31665487 |
| 96 | DAPK2 | 0.30963518 |
| 97 | RPS6KA6 | 0.29569937 |
| 98 | PRKCH | 0.26438634 |
| 99 | CDK4 | 0.25400817 |
| 100 | PRKCD | 0.24549566 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.12027622 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.92253496 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.76981651 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.75825073 |
| 5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.74547027 |
| 6 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.71716644 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.66023587 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.53045628 |
| 9 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.26952991 |
| 10 | Tuberculosis_Homo sapiens_hsa05152 | 2.13801516 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.11335627 |
| 12 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.05731165 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.04636811 |
| 14 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.04555191 |
| 15 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.00952479 |
| 16 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.97511594 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.96526504 |
| 18 | Measles_Homo sapiens_hsa05162 | 1.91851636 |
| 19 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.90744693 |
| 20 | Malaria_Homo sapiens_hsa05144 | 1.86719713 |
| 21 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.84616171 |
| 22 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.70526257 |
| 23 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.69486207 |
| 24 | Viral myocarditis_Homo sapiens_hsa05416 | 1.59477024 |
| 25 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.58875985 |
| 26 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.57247024 |
| 27 | Asthma_Homo sapiens_hsa05310 | 1.52262598 |
| 28 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.51799399 |
| 29 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.51710047 |
| 30 | Legionellosis_Homo sapiens_hsa05134 | 1.51372766 |
| 31 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.46698091 |
| 32 | Influenza A_Homo sapiens_hsa05164 | 1.45370426 |
| 33 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.40045343 |
| 34 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.31202335 |
| 35 | Phagosome_Homo sapiens_hsa04145 | 1.30453985 |
| 36 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.26889008 |
| 37 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.23367868 |
| 38 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.21495950 |
| 39 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.18330756 |
| 40 | Platelet activation_Homo sapiens_hsa04611 | 1.16150803 |
| 41 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.13829173 |
| 42 | Hepatitis B_Homo sapiens_hsa05161 | 1.08243630 |
| 43 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.06757933 |
| 44 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.06324188 |
| 45 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.05695594 |
| 46 | Hepatitis C_Homo sapiens_hsa05160 | 0.98422120 |
| 47 | Apoptosis_Homo sapiens_hsa04210 | 0.96261418 |
| 48 | Pertussis_Homo sapiens_hsa05133 | 0.96022642 |
| 49 | Shigellosis_Homo sapiens_hsa05131 | 0.91947821 |
| 50 | Salmonella infection_Homo sapiens_hsa05132 | 0.88969191 |
| 51 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.88774172 |
| 52 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.85516358 |
| 53 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.81008799 |
| 54 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.80845776 |
| 55 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.79749946 |
| 56 | Other glycan degradation_Homo sapiens_hsa00511 | 0.78839737 |
| 57 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.76823744 |
| 58 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.76540249 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.75601381 |
| 60 | Endocytosis_Homo sapiens_hsa04144 | 0.75204830 |
| 61 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.70626526 |
| 62 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.65642082 |
| 63 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.64298615 |
| 64 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.63249121 |
| 65 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.62605055 |
| 66 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61481804 |
| 67 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.61331549 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.61303466 |
| 69 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.61300632 |
| 70 | Lysosome_Homo sapiens_hsa04142 | 0.59044206 |
| 71 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.58388224 |
| 72 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.57827618 |
| 73 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.57157076 |
| 74 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.56913731 |
| 75 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.56641301 |
| 76 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.56316306 |
| 77 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.54958987 |
| 78 | HTLV-I infection_Homo sapiens_hsa05166 | 0.51916973 |
| 79 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.50287618 |
| 80 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.50157239 |
| 81 | Endometrial cancer_Homo sapiens_hsa05213 | 0.47969459 |
| 82 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.47209519 |
| 83 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.45623696 |
| 84 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.45189320 |
| 85 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.42664912 |
| 86 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.42306923 |
| 87 | Insulin resistance_Homo sapiens_hsa04931 | 0.42076854 |
| 88 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.41995021 |
| 89 | Amoebiasis_Homo sapiens_hsa05146 | 0.41577340 |
| 90 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.41133611 |
| 91 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.39662246 |
| 92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.38697112 |
| 93 | Colorectal cancer_Homo sapiens_hsa05210 | 0.35751258 |
| 94 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.34577566 |
| 95 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.32307743 |
| 96 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.30770339 |
| 97 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.30238460 |
| 98 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.28701091 |
| 99 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.27648862 |
| 100 | Long-term potentiation_Homo sapiens_hsa04720 | 0.26751164 |

