JMY

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of meiosis I (GO:0060631)4.10742135
2nuclear pore complex assembly (GO:0051292)4.02924755
3monoubiquitinated protein deubiquitination (GO:0035520)3.98102771
4histone H3-K4 trimethylation (GO:0080182)3.80791919
5interkinetic nuclear migration (GO:0022027)3.76270388
6mitotic sister chromatid cohesion (GO:0007064)3.56449820
7regulation of DNA methylation (GO:0044030)3.53714522
8nuclear pore organization (GO:0006999)3.51324592
9phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.48168778
10histone H3-K4 methylation (GO:0051568)3.48048498
11positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)3.47796382
12regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)3.47796382
13regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.44107762
14positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.44107762
15protein K11-linked deubiquitination (GO:0035871)3.41658807
16regulation of RNA export from nucleus (GO:0046831)3.26058662
17vesicle transport along microtubule (GO:0047496)3.23479299
18peptidyl-lysine trimethylation (GO:0018023)3.17314814
19negative regulation of histone methylation (GO:0031061)3.16746321
20piRNA metabolic process (GO:0034587)3.12425817
21histone H3-K36 demethylation (GO:0070544)3.12017577
22oocyte development (GO:0048599)3.09324214
23histone lysine methylation (GO:0034968)3.03960788
24negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.02990931
25positive regulation of mRNA catabolic process (GO:0061014)3.01799078
26histone lysine demethylation (GO:0070076)3.00416508
27histone H3-K9 modification (GO:0061647)2.99675418
28regulation of histone H3-K9 methylation (GO:0051570)2.98905597
29cardiac myofibril assembly (GO:0055003)2.96506124
30cytoplasmic mRNA processing body assembly (GO:0033962)2.93380333
31histone demethylation (GO:0016577)2.92475976
32locomotory exploration behavior (GO:0035641)2.92015487
33protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.89018450
34genitalia morphogenesis (GO:0035112)2.87264998
35histone H3-K9 methylation (GO:0051567)2.86010657
36negative regulation of translation, ncRNA-mediated (GO:0040033)2.83790305
37regulation of translation, ncRNA-mediated (GO:0045974)2.83790305
38negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.83790305
39insulin-like growth factor receptor signaling pathway (GO:0048009)2.83018388
40protein K48-linked deubiquitination (GO:0071108)2.78001138
41pore complex assembly (GO:0046931)2.73600459
42meiotic cell cycle (GO:0051321)2.71834639
43negative regulation of potassium ion transmembrane transport (GO:1901380)2.71474744
44microtubule anchoring (GO:0034453)2.71123465
45N-terminal protein amino acid acetylation (GO:0006474)2.70666478
46regulation of mRNA catabolic process (GO:0061013)2.70200112
47stress granule assembly (GO:0034063)2.68067155
48peripheral nervous system axon ensheathment (GO:0032292)2.67141947
49myelination in peripheral nervous system (GO:0022011)2.67141947
50gene silencing by RNA (GO:0031047)2.66964061
51positive regulation of mRNA 3-end processing (GO:0031442)2.66867615
52protein demethylation (GO:0006482)2.65533398
53protein dealkylation (GO:0008214)2.65533398
54cerebellar granule cell differentiation (GO:0021707)2.65105845
55regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.64795927
56protein targeting to Golgi (GO:0000042)2.63653663
57positive regulation of DNA-templated transcription, initiation (GO:2000144)2.62612780
58regulation of nucleobase-containing compound transport (GO:0032239)2.62094377
59regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.61169128
60regulation of cardioblast differentiation (GO:0051890)2.60195699
61positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.58831877
62peptidyl-lysine methylation (GO:0018022)2.58740658
63regulation of acrosome reaction (GO:0060046)2.57831884
64DNA methylation involved in gamete generation (GO:0043046)2.57256706
65regulation of mRNA 3-end processing (GO:0031440)2.57098458
66regulation of histone methylation (GO:0031060)2.56752621
67retinal cone cell development (GO:0046549)2.56383141
68regulation of short-term neuronal synaptic plasticity (GO:0048172)2.56221797
69neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.56038523
70sister chromatid cohesion (GO:0007062)2.52599404
71retrograde transport, vesicle recycling within Golgi (GO:0000301)2.52511964
72establishment of nucleus localization (GO:0040023)2.51602277
73negative regulation of hormone biosynthetic process (GO:0032353)2.51470462
74cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.50979637
75dendritic spine morphogenesis (GO:0060997)2.48491119
76regulation of steroid hormone secretion (GO:2000831)2.47573523
77centrosome localization (GO:0051642)2.45667343
78Golgi to endosome transport (GO:0006895)2.44125231
79keratinization (GO:0031424)2.43858717
80cerebellar Purkinje cell differentiation (GO:0021702)2.43355354
81regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.41122609
82myofibril assembly (GO:0030239)2.40547639
83cell communication involved in cardiac conduction (GO:0086065)2.39959285
84phosphorelay signal transduction system (GO:0000160)2.39316178
85regulation of NFAT protein import into nucleus (GO:0051532)2.39249154
86nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.38587785
87fibroblast migration (GO:0010761)2.35528463
88nucleus organization (GO:0006997)2.35212724
89gastrulation with mouth forming second (GO:0001702)2.35020653
90labyrinthine layer development (GO:0060711)2.34425592
91hippo signaling (GO:0035329)2.34347713
92negative regulation of neurotransmitter secretion (GO:0046929)2.32707891
93positive regulation of histone H3-K4 methylation (GO:0051571)2.31485715
94organelle transport along microtubule (GO:0072384)2.31407405
95asymmetric protein localization (GO:0008105)2.30878579
96camera-type eye morphogenesis (GO:0048593)2.30124744
97regulation of synaptic vesicle exocytosis (GO:2000300)2.28684898
98central nervous system projection neuron axonogenesis (GO:0021952)2.28651025
99establishment of protein localization to Golgi (GO:0072600)2.28621491
100embryonic camera-type eye morphogenesis (GO:0048596)2.28427271
101neuromuscular junction development (GO:0007528)2.27433608
102neuron cell-cell adhesion (GO:0007158)2.27428261
103regulation of corticosteroid hormone secretion (GO:2000846)2.27219715
104histone methylation (GO:0016571)2.27090530
105regulation of DNA-templated transcription, initiation (GO:2000142)2.26107222
106photoreceptor cell differentiation (GO:0046530)2.26087580
107eye photoreceptor cell differentiation (GO:0001754)2.26087580
108regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.25781949
109negative regulation of histone modification (GO:0031057)2.25054490
110nerve growth factor signaling pathway (GO:0038180)2.25010929
111protein K63-linked deubiquitination (GO:0070536)2.24946911
112dendrite morphogenesis (GO:0048813)2.24686597
113regulation of histone H3-K4 methylation (GO:0051569)2.23850036
114layer formation in cerebral cortex (GO:0021819)2.23710505
115cell communication by electrical coupling (GO:0010644)2.23276656
116regulation of axon extension involved in axon guidance (GO:0048841)2.23152411
117regulation of steroid hormone biosynthetic process (GO:0090030)2.23108293
118regulation of female receptivity (GO:0045924)2.22765036
119ventricular cardiac muscle cell action potential (GO:0086005)2.21973887
120phospholipid translocation (GO:0045332)2.21444062
121lipid translocation (GO:0034204)2.21444062
122positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.21277617
123TOR signaling (GO:0031929)2.21115769
124plasma membrane repair (GO:0001778)2.20558866
125regulation of histone H3-K27 methylation (GO:0061085)2.20139764
126cell migration in hindbrain (GO:0021535)2.20115191
127protein deubiquitination (GO:0016579)2.19309014
128cAMP catabolic process (GO:0006198)2.18507647
129regulation of glucocorticoid secretion (GO:2000849)2.18418283
130heart trabecula formation (GO:0060347)2.16552945
131histone H3-K9 demethylation (GO:0033169)2.15909393
132embryonic retina morphogenesis in camera-type eye (GO:0060059)2.14632998
133myotube differentiation (GO:0014902)2.13015759
134positive regulation of catenin import into nucleus (GO:0035413)2.12507419
135glial cell proliferation (GO:0014009)2.11617716
136synaptic vesicle maturation (GO:0016188)2.11328455
137regulation of Rac protein signal transduction (GO:0035020)2.11278472
138negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.10268456
139vocalization behavior (GO:0071625)2.07516464
140apical protein localization (GO:0045176)2.06321700
141sodium ion export (GO:0071436)2.05889009
142regulation of skeletal muscle cell differentiation (GO:2001014)2.04898059
143nucleus localization (GO:0051647)2.04680081
144regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.04457316
145cardiac muscle hypertrophy (GO:0003300)2.04332161
146cytoskeletal anchoring at plasma membrane (GO:0007016)2.03777269
147heart morphogenesis (GO:0003007)2.02887922
148endocardial cushion development (GO:0003197)2.01876661
149axonal fasciculation (GO:0007413)2.01784464
150positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.01668992
151membrane depolarization during cardiac muscle cell action potential (GO:0086012)1.99947387
152regulation of inhibitory postsynaptic membrane potential (GO:0060080)1.99341937
153regulation of actin filament-based movement (GO:1903115)1.99114731
154striated muscle hypertrophy (GO:0014897)1.98929711
155regulation of catenin import into nucleus (GO:0035412)1.98903621
156innervation (GO:0060384)1.98217702
157presynaptic membrane assembly (GO:0097105)1.97895187
158positive regulation of meiosis (GO:0045836)1.97830173
159glutamate secretion (GO:0014047)1.97521095
160regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)1.97110009
161negative regulation of Rho protein signal transduction (GO:0035024)1.96839654
162synaptic vesicle docking involved in exocytosis (GO:0016081)1.96088786
163positive regulation of meiotic cell cycle (GO:0051446)1.95535595
164potassium ion import (GO:0010107)1.94809424
165lymph vessel development (GO:0001945)1.94417881
166morphogenesis of an epithelial sheet (GO:0002011)1.94258036
167regulation of clathrin-mediated endocytosis (GO:2000369)1.94227280
168cell differentiation in hindbrain (GO:0021533)1.93563489
169cardiac muscle contraction (GO:0060048)1.93378626
170regulation of axon guidance (GO:1902667)1.92771721
171sarcomere organization (GO:0045214)1.92638920
172positive regulation of sodium ion transmembrane transporter activity (GO:2000651)1.92283174
173positive regulation of calcium ion transmembrane transporter activity (GO:1901021)1.92171085
174dorsal/ventral axis specification (GO:0009950)1.92080100
175hemidesmosome assembly (GO:0031581)1.91203751
176negative regulation of neurotransmitter transport (GO:0051589)1.91026992
177regulation of protein polyubiquitination (GO:1902914)1.90188219
178gonadal mesoderm development (GO:0007506)1.90186055
179regulation of transforming growth factor beta2 production (GO:0032909)1.90109957
180cardiac conduction (GO:0061337)1.89994187
181regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act1.89845795
182regulation of neuron migration (GO:2001222)1.89562170
183membrane repolarization during cardiac muscle cell action potential (GO:0086013)1.89443538
184desmosome organization (GO:0002934)1.89432005
185cardiac muscle cell proliferation (GO:0060038)1.88935699
186neuron recognition (GO:0008038)1.88766858

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* ZNF217_24962896_ChIP-Seq_MCF-7_Human2.24004166
2CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.19939373
3EZH2_22144423_ChIP-Seq_EOC_Human2.17591835
4GBX2_23144817_ChIP-Seq_PC3_Human2.05470606
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.99851882
6EP300_21415370_ChIP-Seq_HL-1_Mouse1.93393512
7STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.91873588
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.90915472
9RBPJ_22232070_ChIP-Seq_NCS_Mouse1.89679759
10SALL1_21062744_ChIP-ChIP_HESCs_Human1.87279970
11ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.86737429
12JARID2_20064375_ChIP-Seq_MESCs_Mouse1.86336133
13AR_21572438_ChIP-Seq_LNCaP_Human1.83611501
14RNF2_18974828_ChIP-Seq_MESCs_Mouse1.83246371
15EZH2_18974828_ChIP-Seq_MESCs_Mouse1.83246371
16ZFP57_27257070_Chip-Seq_ESCs_Mouse1.77442023
17IGF1R_20145208_ChIP-Seq_DFB_Human1.77338616
18SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.77218399
19PIAS1_25552417_ChIP-Seq_VCAP_Human1.76780424
20FUS_26573619_Chip-Seq_HEK293_Human1.75878719
21TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.73779276
22CDX2_19796622_ChIP-Seq_MESCs_Mouse1.73493985
23* AHR_22903824_ChIP-Seq_MCF-7_Human1.72095207
24RNF2_27304074_Chip-Seq_ESCs_Mouse1.66422186
25* ARNT_22903824_ChIP-Seq_MCF-7_Human1.64761004
26ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.63896747
27TP53_16413492_ChIP-PET_HCT116_Human1.62881082
28ESR1_20079471_ChIP-ChIP_T-47D_Human1.61430153
29AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.60546769
30EZH2_27304074_Chip-Seq_ESCs_Mouse1.58137931
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56986628
32GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.55932698
33MTF2_20144788_ChIP-Seq_MESCs_Mouse1.55162880
34SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.54809344
35KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.51964658
36WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.51904260
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.51385966
38* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.49998336
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49526665
40SMAD_19615063_ChIP-ChIP_OVARY_Human1.49107296
41SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.49058936
42SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.48791394
43CTNNB1_20460455_ChIP-Seq_HCT116_Human1.48631553
44ISL1_27105846_Chip-Seq_CPCs_Mouse1.48526930
45SMAD4_21799915_ChIP-Seq_A2780_Human1.44177047
46DROSHA_22980978_ChIP-Seq_HELA_Human1.44129995
47FOXM1_26456572_ChIP-Seq_MCF-7_Human1.42259591
48* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.41676929
49TCF4_18268006_ChIP-ChIP_LS174T_Human1.41467344
50SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40742334
51JARID2_20075857_ChIP-Seq_MESCs_Mouse1.40007432
52EED_16625203_ChIP-ChIP_MESCs_Mouse1.39575466
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39481797
54STAT6_21828071_ChIP-Seq_BEAS2B_Human1.38414358
55HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.37511951
56OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34927484
57SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.34019725
58RARB_27405468_Chip-Seq_BRAIN_Mouse1.32884748
59* STAT3_23295773_ChIP-Seq_U87_Human1.31752647
60TAF15_26573619_Chip-Seq_HEK293_Human1.31233864
61* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.30972470
62KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.28025293
63KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.28025293
64KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.28025293
65BCAT_22108803_ChIP-Seq_LS180_Human1.27722099
66TP63_19390658_ChIP-ChIP_HaCaT_Human1.27417290
67TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27377908
68RNF2_27304074_Chip-Seq_NSC_Mouse1.26430393
69RXR_22108803_ChIP-Seq_LS180_Human1.26393013
70CTBP2_25329375_ChIP-Seq_LNCAP_Human1.26182268
71ESR2_21235772_ChIP-Seq_MCF-7_Human1.25499074
72VDR_22108803_ChIP-Seq_LS180_Human1.24971642
73EZH2_27294783_Chip-Seq_ESCs_Mouse1.23305647
74SMAD3_21741376_ChIP-Seq_EPCs_Human1.22859177
75BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.22721177
76RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.22714034
77* SOX2_21211035_ChIP-Seq_LN229_Gbm1.21923568
78YAP1_20516196_ChIP-Seq_MESCs_Mouse1.21567600
79STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.21478748
80ZNF274_21170338_ChIP-Seq_K562_Hela1.21380610
81EWS_26573619_Chip-Seq_HEK293_Human1.20770786
82UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20697573
83FLI1_27457419_Chip-Seq_LIVER_Mouse1.20337897
84CTBP1_25329375_ChIP-Seq_LNCAP_Human1.19747922
85NR3C1_23031785_ChIP-Seq_PC12_Mouse1.19038775
86RING1B_27294783_Chip-Seq_NPCs_Mouse1.18524562
87* FLI1_21867929_ChIP-Seq_TH2_Mouse1.17980092
88POU3F2_20337985_ChIP-ChIP_501MEL_Human1.17925960
89EZH2_27294783_Chip-Seq_NPCs_Mouse1.17467879
90TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.16822285
91WT1_19549856_ChIP-ChIP_CCG9911_Human1.16543300
92NR3C1_21868756_ChIP-Seq_MCF10A_Human1.16435677
93PKCTHETA_26484144_Chip-Seq_BREAST_Human1.16248941
94CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.16110037
95* TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.15845847
96* AR_19668381_ChIP-Seq_PC3_Human1.15839058
97FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.15306584
98SUZ12_27294783_Chip-Seq_ESCs_Mouse1.14581687
99P300_19829295_ChIP-Seq_ESCs_Human1.14274311
100LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14069477
101ZNF263_19887448_ChIP-Seq_K562_Human1.13753463
102TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.13352762
103NANOG_18555785_Chip-Seq_ESCs_Mouse1.13059417
104RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12681008
105TCF4_23295773_ChIP-Seq_U87_Human1.11437665
106CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.11383316
107AR_25329375_ChIP-Seq_VCAP_Human1.09955006
108TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08285929
109POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08285929
110SMAD3_21741376_ChIP-Seq_HESCs_Human1.08276223
111SMAD4_21741376_ChIP-Seq_HESCs_Human1.07569706
112SOX9_24532713_ChIP-Seq_HFSC_Mouse1.07507320
113PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.07391925
114ER_23166858_ChIP-Seq_MCF-7_Human1.07069639
115RUNX2_22187159_ChIP-Seq_PCA_Human1.07068031
116TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06934338
117KDM2B_26808549_Chip-Seq_K562_Human1.06814401
118PRDM14_20953172_ChIP-Seq_ESCs_Human1.05947438
119STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.05470956
120FOXA2_19822575_ChIP-Seq_HepG2_Human1.05322608
121FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.05166466
122CLOCK_20551151_ChIP-Seq_293T_Human1.04873849
123SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.04782152
124TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03981741
125ESR1_21235772_ChIP-Seq_MCF-7_Human1.03861390
126PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03751249
127TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.03212593
128ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03139968
129* FOXO3_23340844_ChIP-Seq_DLD1_Human1.01883352
130TP53_18474530_ChIP-ChIP_U2OS_Human1.01011408
131CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00988504
132CBP_20019798_ChIP-Seq_JUKART_Human1.00972270
133IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.00972270
134PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00962123
135NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.00387572
136NRF2_20460467_ChIP-Seq_MEFs_Mouse1.00387572
137RING1B_27294783_Chip-Seq_ESCs_Mouse0.99585164
138MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.99264703
139SOX9_26525672_Chip-Seq_HEART_Mouse0.99174100
140E2F1_18555785_Chip-Seq_ESCs_Mouse0.98628147
141* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.96985284
142TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.96771718
143PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.96046951

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.60452393
2MP0008877_abnormal_DNA_methylation3.33254490
3MP0003890_abnormal_embryonic-extraembry3.16927834
4MP0009780_abnormal_chondrocyte_physiolo2.29253424
5MP0005423_abnormal_somatic_nervous2.26528034
6MP0004084_abnormal_cardiac_muscle2.13669303
7MP0005409_darkened_coat_color2.09344353
8MP0004885_abnormal_endolymph2.05888462
9MP0001188_hyperpigmentation2.03758335
10MP0004145_abnormal_muscle_electrophysio2.03045664
11MP0002796_impaired_skin_barrier1.90036030
12MP0004270_analgesia1.86999344
13MP0004215_abnormal_myocardial_fiber1.84924118
14MP0010352_gastrointestinal_tract_polyps1.81080183
15MP0004859_abnormal_synaptic_plasticity1.79783655
16MP0001299_abnormal_eye_distance/1.78764200
17MP0005623_abnormal_meninges_morphology1.72526990
18MP0010678_abnormal_skin_adnexa1.72134735
19MP0003121_genomic_imprinting1.71314469
20MP0002837_dystrophic_cardiac_calcinosis1.71196196
21MP0000751_myopathy1.70530519
22MP0010234_abnormal_vibrissa_follicle1.68066055
23MP0000569_abnormal_digit_pigmentation1.68046255
24MP0002009_preneoplasia1.66531214
25MP0004036_abnormal_muscle_relaxation1.61722341
26MP0000778_abnormal_nervous_system1.59809293
27MP0001502_abnormal_circadian_rhythm1.59091245
28MP0000383_abnormal_hair_follicle1.56055969
29MP0000579_abnormal_nail_morphology1.55999064
30MP0006138_congestive_heart_failure1.52088101
31MP0004272_abnormal_basement_membrane1.50008638
32MP0003385_abnormal_body_wall1.43723443
33MP0003635_abnormal_synaptic_transmissio1.39472712
34MP0000537_abnormal_urethra_morphology1.39458900
35MP0005503_abnormal_tendon_morphology1.37742412
36MP0004484_altered_response_of1.34314380
37MP0001984_abnormal_olfaction1.34174550
38MP0005620_abnormal_muscle_contractility1.32598399
39MP0009384_cardiac_valve_regurgitation1.32298655
40MP0003123_paternal_imprinting1.31963259
41MP0001486_abnormal_startle_reflex1.30314238
42MP0004085_abnormal_heartbeat1.29575018
43MP0005076_abnormal_cell_differentiation1.29563349
44MP0004087_abnormal_muscle_fiber1.29395102
45MP0000647_abnormal_sebaceous_gland1.28737700
46MP0003718_maternal_effect1.28321935
47MP0002160_abnormal_reproductive_system1.27664187
48MP0005187_abnormal_penis_morphology1.27025362
49MP0004130_abnormal_muscle_cell1.25552344
50MP0001177_atelectasis1.25394403
51MP0002972_abnormal_cardiac_muscle1.25330426
52MP0006292_abnormal_olfactory_placode1.24111746
53MP0000749_muscle_degeneration1.23770069
54MP0002108_abnormal_muscle_morphology1.22902070
55MP0001661_extended_life_span1.22413222
56MP0003122_maternal_imprinting1.20308682
57MP0004381_abnormal_hair_follicle1.20277793
58MP0005330_cardiomyopathy1.19979070
59MP0000427_abnormal_hair_cycle1.19977122
60MP0000428_abnormal_craniofacial_morphol1.19906754
61MP0004147_increased_porphyrin_level1.19706092
62MP0010630_abnormal_cardiac_muscle1.19629841
63MP0003705_abnormal_hypodermis_morpholog1.19170168
64MP0003045_fibrosis1.18582676
65MP0003935_abnormal_craniofacial_develop1.18095829
66MP0009250_abnormal_appendicular_skeleto1.17069140
67MP0000733_abnormal_muscle_development1.16843799
68MP0001879_abnormal_lymphatic_vessel1.15834177
69MP0002877_abnormal_melanocyte_morpholog1.15641443
70MP0003828_pulmonary_edema1.14526235
71MP0002210_abnormal_sex_determination1.13994938
72MP0001929_abnormal_gametogenesis1.13295895
73MP0003950_abnormal_plasma_membrane1.10533680
74MP0003879_abnormal_hair_cell1.10200965
75MP0000003_abnormal_adipose_tissue1.09950838
76MP0000747_muscle_weakness1.09649857
77MP0006276_abnormal_autonomic_nervous1.09146363
78MP0003115_abnormal_respiratory_system1.08439809
79MP0005394_taste/olfaction_phenotype1.06105965
80MP0005499_abnormal_olfactory_system1.06105965
81MP0005275_abnormal_skin_tensile1.05774652
82MP0008775_abnormal_heart_ventricle1.04824769
83MP0002063_abnormal_learning/memory/cond1.04708039
84MP0000534_abnormal_ureter_morphology1.04405635
85MP0002638_abnormal_pupillary_reflex1.03671389
86MP0001485_abnormal_pinna_reflex1.03320219
87MP0002166_altered_tumor_susceptibility1.02406867
88MP0003755_abnormal_palate_morphology1.01801903
89MP0008569_lethality_at_weaning1.00616168
90MP0003880_abnormal_central_pattern0.99867797
91MP0010368_abnormal_lymphatic_system0.99383801
92MP0003699_abnormal_female_reproductive0.98488448
93MP0003937_abnormal_limbs/digits/tail_de0.97575261
94MP0002106_abnormal_muscle_physiology0.96531443
95MP0004742_abnormal_vestibular_system0.96283784
96MP0001440_abnormal_grooming_behavior0.95687495
97MP0002127_abnormal_cardiovascular_syste0.95656581
98MP0003878_abnormal_ear_physiology0.95054579
99MP0005377_hearing/vestibular/ear_phenot0.95054579
100MP0005369_muscle_phenotype0.94693675
101MP0009046_muscle_twitch0.94653290
102MP0004233_abnormal_muscle_weight0.92454614
103MP0003787_abnormal_imprinting0.90899132
104MP0003137_abnormal_impulse_conducting0.90456901
105MP0004197_abnormal_fetal_growth/weight/0.90367616
106MP0002734_abnormal_mechanical_nocicepti0.90083789
107MP0000631_abnormal_neuroendocrine_gland0.89636727
108MP0001919_abnormal_reproductive_system0.88996784
109MP0000462_abnormal_digestive_system0.88786432
110MP0000759_abnormal_skeletal_muscle0.88161888
111MP0003698_abnormal_male_reproductive0.88129890
112MP0003567_abnormal_fetal_cardiomyocyte0.87932061
113MP0002233_abnormal_nose_morphology0.87383349
114MP0008961_abnormal_basal_metabolism0.86819722
115MP0002234_abnormal_pharynx_morphology0.86714703
116MP0001784_abnormal_fluid_regulation0.86139340
117MP0002098_abnormal_vibrissa_morphology0.85482698
118MP0008995_early_reproductive_senescence0.85170235
119MP0000762_abnormal_tongue_morphology0.84185741
120MP0008789_abnormal_olfactory_epithelium0.84125226
121MP0005551_abnormal_eye_electrophysiolog0.84049963
122MP0002184_abnormal_innervation0.83877099
123MP0009745_abnormal_behavioral_response0.83854215
124MP0002925_abnormal_cardiovascular_devel0.83661759
125MP0001501_abnormal_sleep_pattern0.83085479
126MP0002272_abnormal_nervous_system0.82699669
127MP0002133_abnormal_respiratory_system0.82209625
128MP0005388_respiratory_system_phenotype0.82209625
129MP0005385_cardiovascular_system_phenoty0.81678188
130MP0001544_abnormal_cardiovascular_syste0.81678188
131MP0009703_decreased_birth_body0.80469091
132MP0002896_abnormal_bone_mineralization0.80320354
133MP0003763_abnormal_thymus_physiology0.80172015
134MP0004185_abnormal_adipocyte_glucose0.79838953
135MP0002064_seizures0.79607754
136MP0000955_abnormal_spinal_cord0.79589058
137MP0000653_abnormal_sex_gland0.79563380
138MP0000432_abnormal_head_morphology0.79044609
139MP0009115_abnormal_fat_cell0.75865401
140MP0000566_synostosis0.75412979
141MP0005389_reproductive_system_phenotype0.74581950
142MP0001145_abnormal_male_reproductive0.73898075
143MP0004924_abnormal_behavior0.73417629
144MP0005386_behavior/neurological_phenoty0.73417629
145MP0004043_abnormal_pH_regulation0.73229592
146MP0002006_tumorigenesis0.72966364
147MP0000377_abnormal_hair_follicle0.71293179
148MP0002088_abnormal_embryonic_growth/wei0.71207573
149MP0001672_abnormal_embryogenesis/_devel0.70499627
150MP0005380_embryogenesis_phenotype0.70499627
151MP0005647_abnormal_sex_gland0.70176632
152MP0001340_abnormal_eyelid_morphology0.70113384
153MP0002084_abnormal_developmental_patter0.69840154
154MP0002557_abnormal_social/conspecific_i0.69475758
155MP0003861_abnormal_nervous_system0.69299303
156MP0002572_abnormal_emotion/affect_behav0.69240706

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.59542842
2Heterotopia (HP:0002282)3.31964248
3Lip pit (HP:0100267)3.31336824
4Truncal obesity (HP:0001956)3.29868610
5Hyporeflexia of lower limbs (HP:0002600)3.16667785
6Cubitus valgus (HP:0002967)2.98149150
7Obstructive sleep apnea (HP:0002870)2.79015350
8Asymmetry of the thorax (HP:0001555)2.74087222
9Macroorchidism (HP:0000053)2.70664112
10Curly hair (HP:0002212)2.66856495
11Fair hair (HP:0002286)2.58433430
12Abnormality of the nasal septum (HP:0000419)2.55703941
13Sudden death (HP:0001699)2.55026796
14Genetic anticipation (HP:0003743)2.48780089
15Aqueductal stenosis (HP:0002410)2.48548927
16Termporal pattern (HP:0011008)2.47971524
17Insidious onset (HP:0003587)2.47971524
18Papillary thyroid carcinoma (HP:0002895)2.47869822
19Shallow orbits (HP:0000586)2.43303249
20Calf muscle hypertrophy (HP:0008981)2.42677862
21Muscle hypertrophy of the lower extremities (HP:0008968)2.41432048
22Cystic hygroma (HP:0000476)2.40904044
23Hyperkalemia (HP:0002153)2.39987525
24Abnormality of the calf musculature (HP:0001430)2.39473781
25Exercise-induced myalgia (HP:0003738)2.39052354
26Broad metatarsal (HP:0001783)2.35145307
27Aplasia involving bones of the extremities (HP:0009825)2.27663898
28Aplasia involving bones of the upper limbs (HP:0009823)2.27663898
29Aplasia of the phalanges of the hand (HP:0009802)2.27663898
30Protruding tongue (HP:0010808)2.24524904
31Hypoplastic nipples (HP:0002557)2.24001593
32Right ventricular cardiomyopathy (HP:0011663)2.23338831
33Muscle fiber splitting (HP:0003555)2.19270168
34Ventricular fibrillation (HP:0001663)2.19030209
35Oligodactyly (hands) (HP:0001180)2.18097995
36Narrow palate (HP:0000189)2.15485815
37Hyperventilation (HP:0002883)2.12644287
38Increased connective tissue (HP:0009025)2.11863637
39Thickened helices (HP:0000391)2.09053775
40Gaze-evoked nystagmus (HP:0000640)2.08896082
41Sandal gap (HP:0001852)2.07083460
42Neoplasm of the tracheobronchial system (HP:0100552)2.06942243
43Dysdiadochokinesis (HP:0002075)2.05849487
44Overgrowth (HP:0001548)2.04278135
45Biliary tract neoplasm (HP:0100574)2.03328518
46Deep palmar crease (HP:0006191)2.03152081
47Dysmetric saccades (HP:0000641)2.01852804
48Nephroblastoma (Wilms tumor) (HP:0002667)2.00066235
49Focal motor seizures (HP:0011153)1.99905378
50Subaortic stenosis (HP:0001682)1.98645737
51Abnormality of the left ventricular outflow tract (HP:0011103)1.98645737
52Humeroradial synostosis (HP:0003041)1.98584460
53Synostosis involving the elbow (HP:0003938)1.98584460
54Generalized hypopigmentation of hair (HP:0011358)1.98526234
55Subacute progressive viral hepatitis (HP:0006572)1.97865665
56Difficulty running (HP:0009046)1.97816952
57Atonic seizures (HP:0010819)1.97464221
58Lymphangioma (HP:0100764)1.95413319
59Bronchomalacia (HP:0002780)1.92859171
60Menstrual irregularities (HP:0000858)1.92327638
61Febrile seizures (HP:0002373)1.91754565
62Abnormality of the corticospinal tract (HP:0002492)1.90348921
63Prolonged QT interval (HP:0001657)1.90095746
64Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.89980923
65Syncope (HP:0001279)1.88975167
66Short chin (HP:0000331)1.87421864
67Exercise-induced muscle cramps (HP:0003710)1.87032619
68Embryonal renal neoplasm (HP:0011794)1.86996534
69Abnormality of chromosome segregation (HP:0002916)1.86633670
70Progressive cerebellar ataxia (HP:0002073)1.86476577
71Excessive salivation (HP:0003781)1.85643253
72Drooling (HP:0002307)1.85643253
73Truncal ataxia (HP:0002078)1.84418802
74Transitional cell carcinoma of the bladder (HP:0006740)1.84094599
75Hypoplastic ischia (HP:0003175)1.81892897
76Atrial fibrillation (HP:0005110)1.81105514
77Acute myeloid leukemia (HP:0004808)1.81026384
78Abnormality of the lower motor neuron (HP:0002366)1.80793456
79Abnormal biliary tract morphology (HP:0012440)1.80692740
80Chromsome breakage (HP:0040012)1.80593017
81Focal seizures (HP:0007359)1.80581746
82Osteomalacia (HP:0002749)1.80194973
83Overlapping toe (HP:0001845)1.79692037
84Epileptic encephalopathy (HP:0200134)1.78902350
85Neoplasm of the oral cavity (HP:0100649)1.77933149
86Abnormality of the fingertips (HP:0001211)1.77105961
87Rectal prolapse (HP:0002035)1.77059753
88Abnormal hair whorl (HP:0010721)1.76864651
89Thyroid carcinoma (HP:0002890)1.76741494
90Hypoplastic labia majora (HP:0000059)1.75782076
91Bundle branch block (HP:0011710)1.75631035
92Action tremor (HP:0002345)1.75434412
93Vertebral arch anomaly (HP:0008438)1.75098340
94Aortic aneurysm (HP:0004942)1.75010648
95Cutaneous finger syndactyly (HP:0010554)1.74998577
96Bladder carcinoma (HP:0002862)1.74240923
97Bladder neoplasm (HP:0009725)1.74240923
98Deep philtrum (HP:0002002)1.73845510
99Arterial tortuosity (HP:0005116)1.73787348
100Anteriorly placed anus (HP:0001545)1.73423782
101Abnormality of incisor morphology (HP:0011063)1.73335266
102Neonatal hypoglycemia (HP:0001998)1.73259038
103Scapular winging (HP:0003691)1.72779139
104Chronic hepatic failure (HP:0100626)1.72496830
105Abnormality of the ischium (HP:0003174)1.71518517
106Hypoplasia of the iris (HP:0007676)1.70999854
107Wide intermamillary distance (HP:0006610)1.70748242
108Follicular hyperkeratosis (HP:0007502)1.70597953
109Hepatoblastoma (HP:0002884)1.70481229
110Vascular tortuosity (HP:0004948)1.69999866
111Papilledema (HP:0001085)1.69789859
112Midline defect of the nose (HP:0004122)1.69616117
113Alveolar cell carcinoma (HP:0006519)1.69454060
114Dislocated radial head (HP:0003083)1.68159437
115Complete atrioventricular canal defect (HP:0001674)1.68118771
116Anhidrosis (HP:0000970)1.67461679
117Laryngomalacia (HP:0001601)1.67079731
118Relative macrocephaly (HP:0004482)1.67034960
119Degeneration of the lateral corticospinal tracts (HP:0002314)1.66998836
120Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.66998836
121Oligodactyly (HP:0012165)1.66914457
122Broad-based gait (HP:0002136)1.66914088
123Gonadotropin excess (HP:0000837)1.66792228
124Primary atrial arrhythmia (HP:0001692)1.66051032
125Buphthalmos (HP:0000557)1.65986488
126Urinary bladder sphincter dysfunction (HP:0002839)1.65871166
127Enlarged penis (HP:0000040)1.65414348
128Gastrointestinal carcinoma (HP:0002672)1.65015968
129Malignant gastrointestinal tract tumors (HP:0006749)1.65015968
130Hamartoma (HP:0010566)1.64936043
131Abnormality of the parietal bone (HP:0002696)1.63535386
132Absent eyebrow (HP:0002223)1.63033532
133Neoplasm of the small intestine (HP:0100833)1.62675926
134Abnormality of nail color (HP:0100643)1.62324388
135Abnormality of the parathyroid morphology (HP:0011766)1.61974747
136Coronal craniosynostosis (HP:0004440)1.61384273
137Impaired social interactions (HP:0000735)1.61123999
138Abnormal social behavior (HP:0012433)1.61123999
139Urethral obstruction (HP:0000796)1.61045581
140Skin pits (HP:0100276)1.59958569
141Aortic dissection (HP:0002647)1.59779686
142Cutaneous syndactyly (HP:0012725)1.59648245
143Hypoplasia of the maxilla (HP:0000327)1.59531510
144Pulmonic stenosis (HP:0001642)1.59463502
145Increased variability in muscle fiber diameter (HP:0003557)1.58943794
146Type 1 muscle fiber predominance (HP:0003803)1.58770798
147Germ cell neoplasia (HP:0100728)1.58749747
148Short 4th metacarpal (HP:0010044)1.58298895
149Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.58298895
150Abnormality of the labia majora (HP:0012881)1.58208927
151Depressed nasal tip (HP:0000437)1.58113669
152Abnormal pancreas size (HP:0012094)1.57334292
153Blue irides (HP:0000635)1.57104584
154Astrocytoma (HP:0009592)1.56800099
155Abnormality of the astrocytes (HP:0100707)1.56800099
156Ventricular arrhythmia (HP:0004308)1.56509547
157Thick eyebrow (HP:0000574)1.56475115
158Hamartoma of the eye (HP:0010568)1.56327909
159Megalencephaly (HP:0001355)1.56264290
160Deeply set eye (HP:0000490)1.55750971
161Abnormality of the radial head (HP:0003995)1.55696010
162Open mouth (HP:0000194)1.55646206
163Abnormality of the phalanges of the hallux (HP:0010057)1.55642627
164Low anterior hairline (HP:0000294)1.55610153
165Labial hypoplasia (HP:0000066)1.55348512
166Sparse lateral eyebrow (HP:0005338)1.55128085
167Chromosomal breakage induced by crosslinking agents (HP:0003221)1.54551994
168Widely spaced teeth (HP:0000687)1.54323621
169Abnormality of secondary sexual hair (HP:0009888)1.54087486
170Abnormality of the axillary hair (HP:0100134)1.54087486
171Absent eyelashes (HP:0000561)1.53905960
172Mitral valve prolapse (HP:0001634)1.53770701
173Milia (HP:0001056)1.53416155
174Central scotoma (HP:0000603)1.52958750

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS13.32413513
2FGFR22.97552601
3AKT32.44312296
4NLK2.16553840
5CAMK1G2.09304204
6MAP3K41.74215212
7TYRO31.71709947
8DMPK1.69237807
9SGK21.67436765
10SIK21.64443453
11STK391.63810108
12PRPF4B1.59079347
13OBSCN1.55698926
14WNK11.53892222
15PHKG21.53094615
16PHKG11.53094615
17PDGFRA1.50270301
18CDK121.47427795
19PRKD31.45654480
20SGK31.42280456
21SGK2231.41318627
22SGK4941.41318627
23MAP3K101.40427332
24MAP3K21.39047244
25CAMK1D1.38451228
26RIPK11.37768079
27NTRK31.34826669
28FRK1.34461779
29STK31.33471821
30MAP3K131.32451722
31MARK11.31726269
32EPHA41.31550664
33LATS21.26645887
34TTN1.23631253
35TNIK1.21366693
36EPHB11.20369299
37IRAK11.20236670
38PDGFRB1.20000989
39PAK31.14971881
40WNK41.14638314
41FGFR31.14410986
42PNCK1.10534089
43PIK3CA1.06949048
44MELK1.06459588
45PAK61.04858735
46MAP2K41.04711245
47FER1.01757165
48MAPK131.01170649
49BRD41.00226666
50FGFR10.98294735
51RPS6KB10.96735324
52RET0.95627386
53STK380.94558887
54SIK10.94253910
55ICK0.93246004
56MKNK20.92958932
57OXSR10.91137377
58DDR20.90708203
59TRPM70.88345211
60NUAK10.86672429
61MAP3K70.85916810
62NTRK20.85322192
63MTOR0.82824518
64EPHB20.81660210
65IRAK20.80976748
66SGK10.79405665
67LMTK20.79133915
68PKN20.78944792
69UHMK10.78280061
70PRKCH0.77932719
71TAOK30.76536443
72PKN10.75588788
73DAPK20.74538965
74TIE10.74411271
75PAK20.74267102
76ROCK10.73158909
77MINK10.73081528
78PLK20.72032701
79EPHA30.71797490
80DYRK1A0.71773018
81STK110.70728612
82ERBB30.70382501
83PRKAA10.68103911
84PTK60.67915426
85HIPK20.67880624
86NTRK10.67821567
87STK38L0.67300729
88MAP3K90.66552102
89PTK2B0.65504441
90PRKAA20.64477496
91BCR0.64391784
92MARK20.63417351
93CHUK0.61638222
94PDK40.61180859
95PDK30.61180859
96NEK60.61070739
97CAMK10.58381083
98WNK30.56970973
99CAMK40.56680823
100CDK50.56444206
101CDK30.56080697
102KSR20.55997002
103CSNK1E0.55751535
104CAMKK10.55625665
105GSK3B0.55131537
106MAPK100.54846248
107CSNK1D0.54466076
108INSRR0.53936790
109MAPK70.53890203
110RAF10.52973388
111PRKD10.52908415
112TRIB30.52452052
113BRAF0.52138400
114MAPK80.51569087
115SIK30.51482058
116EEF2K0.51294266
117RPS6KA30.51205052
118TAF10.50774335
119KSR10.50496714
120ATM0.49990301
121CASK0.49830860
122CDK90.48944331
123RPS6KB20.48472756
124MARK30.48358647
125CHEK10.48250337
126PRKCE0.48093457
127STK240.47734447
128ALK0.47637663
129JAK10.44983102
130CDK20.44946808
131MAPK120.43444372
132NEK90.42174673
133PIM10.40530505
134MAPK10.39360762

Predicted pathways (KEGG)

RankGene SetZ-score
1Dilated cardiomyopathy_Homo sapiens_hsa054141.75779820
2Long-term potentiation_Homo sapiens_hsa047201.69888805
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.68046057
4Dorso-ventral axis formation_Homo sapiens_hsa043201.53666062
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.52710984
6Nitrogen metabolism_Homo sapiens_hsa009101.52078905
7Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.48379825
8Axon guidance_Homo sapiens_hsa043601.42986711
9Circadian entrainment_Homo sapiens_hsa047131.37713274
10Thyroid cancer_Homo sapiens_hsa052161.37449781
11mRNA surveillance pathway_Homo sapiens_hsa030151.37326953
12Glutamatergic synapse_Homo sapiens_hsa047241.36251762
13Aldosterone synthesis and secretion_Homo sapiens_hsa049251.34732366
14Gastric acid secretion_Homo sapiens_hsa049711.34096780
15Circadian rhythm_Homo sapiens_hsa047101.31783875
16Salivary secretion_Homo sapiens_hsa049701.30882541
17Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.30331376
18Oxytocin signaling pathway_Homo sapiens_hsa049211.27747754
19GABAergic synapse_Homo sapiens_hsa047271.27711086
20cGMP-PKG signaling pathway_Homo sapiens_hsa040221.26998450
21Endometrial cancer_Homo sapiens_hsa052131.26817346
22Renal cell carcinoma_Homo sapiens_hsa052111.26227251
23Adherens junction_Homo sapiens_hsa045201.25558890
24ECM-receptor interaction_Homo sapiens_hsa045121.25514665
25Dopaminergic synapse_Homo sapiens_hsa047281.25333107
26Focal adhesion_Homo sapiens_hsa045101.25033920
27Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.23770005
28Fatty acid biosynthesis_Homo sapiens_hsa000611.22566722
29Hippo signaling pathway_Homo sapiens_hsa043901.22114327
30Thyroid hormone signaling pathway_Homo sapiens_hsa049191.21785246
31Amphetamine addiction_Homo sapiens_hsa050311.21579549
32Renin secretion_Homo sapiens_hsa049241.21140079
33Tight junction_Homo sapiens_hsa045301.20813516
34Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.19473089
35Cholinergic synapse_Homo sapiens_hsa047251.19229892
36Insulin secretion_Homo sapiens_hsa049111.18683569
37Type II diabetes mellitus_Homo sapiens_hsa049301.18286231
38Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.18178774
39Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.17677651
40Glioma_Homo sapiens_hsa052141.17516324
41Melanogenesis_Homo sapiens_hsa049161.17309662
42Oocyte meiosis_Homo sapiens_hsa041141.17171437
43Basal cell carcinoma_Homo sapiens_hsa052171.15102072
44T cell receptor signaling pathway_Homo sapiens_hsa046601.14871505
45ErbB signaling pathway_Homo sapiens_hsa040121.14546300
46cAMP signaling pathway_Homo sapiens_hsa040241.13459299
47mTOR signaling pathway_Homo sapiens_hsa041501.12058391
48Vascular smooth muscle contraction_Homo sapiens_hsa042701.11999328
49GnRH signaling pathway_Homo sapiens_hsa049121.11367403
50Estrogen signaling pathway_Homo sapiens_hsa049151.10923171
51Neurotrophin signaling pathway_Homo sapiens_hsa047221.10728961
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.10362940
53ABC transporters_Homo sapiens_hsa020101.08933896
54Cell cycle_Homo sapiens_hsa041101.08401417
55Pancreatic cancer_Homo sapiens_hsa052121.06968167
56Wnt signaling pathway_Homo sapiens_hsa043101.06461016
57Phosphatidylinositol signaling system_Homo sapiens_hsa040701.06210122
58Hedgehog signaling pathway_Homo sapiens_hsa043401.05432089
59Insulin resistance_Homo sapiens_hsa049311.05425954
60Lysine degradation_Homo sapiens_hsa003101.04334879
61Long-term depression_Homo sapiens_hsa047301.02806009
62Acute myeloid leukemia_Homo sapiens_hsa052211.02516890
63Basal transcription factors_Homo sapiens_hsa030221.02236024
64Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.00877272
65Longevity regulating pathway - mammal_Homo sapiens_hsa042110.99721645
66Morphine addiction_Homo sapiens_hsa050320.99116714
67Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.98941104
68Olfactory transduction_Homo sapiens_hsa047400.98548866
69Nicotine addiction_Homo sapiens_hsa050330.98057587
70Proteoglycans in cancer_Homo sapiens_hsa052050.97562968
71Calcium signaling pathway_Homo sapiens_hsa040200.97522867
72Taste transduction_Homo sapiens_hsa047420.97191939
73TGF-beta signaling pathway_Homo sapiens_hsa043500.97164499
74Prostate cancer_Homo sapiens_hsa052150.97080398
75Phototransduction_Homo sapiens_hsa047440.95706256
76Glucagon signaling pathway_Homo sapiens_hsa049220.93790913
77Serotonergic synapse_Homo sapiens_hsa047260.93676961
78RNA degradation_Homo sapiens_hsa030180.91320557
79Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.90444399
80Choline metabolism in cancer_Homo sapiens_hsa052310.90288348
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.89012205
82Insulin signaling pathway_Homo sapiens_hsa049100.88856113
83MicroRNAs in cancer_Homo sapiens_hsa052060.88120213
84MAPK signaling pathway_Homo sapiens_hsa040100.85333522
85Gap junction_Homo sapiens_hsa045400.85118184
86FoxO signaling pathway_Homo sapiens_hsa040680.84919893
87Regulation of autophagy_Homo sapiens_hsa041400.84669893
88Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.81643314
89AMPK signaling pathway_Homo sapiens_hsa041520.81343934
90Fatty acid metabolism_Homo sapiens_hsa012120.79719053
91Central carbon metabolism in cancer_Homo sapiens_hsa052300.79379300
92Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.79341265
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.77818408
94Ovarian steroidogenesis_Homo sapiens_hsa049130.76681368
95VEGF signaling pathway_Homo sapiens_hsa043700.76309124
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.75909860
97Thyroid hormone synthesis_Homo sapiens_hsa049180.75606529
98Pancreatic secretion_Homo sapiens_hsa049720.74263355
99Ras signaling pathway_Homo sapiens_hsa040140.73189005
100Rap1 signaling pathway_Homo sapiens_hsa040150.72345909
101Adipocytokine signaling pathway_Homo sapiens_hsa049200.71955049
102Melanoma_Homo sapiens_hsa052180.70421714
103Non-small cell lung cancer_Homo sapiens_hsa052230.69128496
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68016168
105Synaptic vesicle cycle_Homo sapiens_hsa047210.67549611
106Prolactin signaling pathway_Homo sapiens_hsa049170.67253398
107Chronic myeloid leukemia_Homo sapiens_hsa052200.66808991
108Protein digestion and absorption_Homo sapiens_hsa049740.65752227
109Inositol phosphate metabolism_Homo sapiens_hsa005620.62426985
110Colorectal cancer_Homo sapiens_hsa052100.61964507
111Cocaine addiction_Homo sapiens_hsa050300.61942140
112B cell receptor signaling pathway_Homo sapiens_hsa046620.60809449
113AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.60527675
114Carbohydrate digestion and absorption_Homo sapiens_hsa049730.59304241
115PI3K-Akt signaling pathway_Homo sapiens_hsa041510.59169057
116Bile secretion_Homo sapiens_hsa049760.58649203
117Sphingolipid signaling pathway_Homo sapiens_hsa040710.58589998
118Cardiac muscle contraction_Homo sapiens_hsa042600.58400659
119RNA transport_Homo sapiens_hsa030130.57742645
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.56989516
121Pathways in cancer_Homo sapiens_hsa052000.54289323
122Small cell lung cancer_Homo sapiens_hsa052220.52711231

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