JTB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)6.11926366
2DNA deamination (GO:0045006)5.73190244
3signal peptide processing (GO:0006465)4.34836603
4maturation of SSU-rRNA (GO:0030490)4.22797524
5pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.00461616
6viral life cycle (GO:0019058)3.96838854
7mitochondrial calcium ion transport (GO:0006851)3.86964814
8deoxyribose phosphate biosynthetic process (GO:0046385)3.73804431
92-deoxyribonucleotide biosynthetic process (GO:0009265)3.73804431
10nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.69257029
11proteasome assembly (GO:0043248)3.61713807
12cellular protein complex disassembly (GO:0043624)3.61037295
13mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.58521625
14ribosomal small subunit assembly (GO:0000028)3.57670494
15L-phenylalanine metabolic process (GO:0006558)3.50908899
16erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.50908899
17pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.49632481
18respiratory chain complex IV assembly (GO:0008535)3.43890533
19negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.39334183
20erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.38821035
21L-phenylalanine catabolic process (GO:0006559)3.38821035
22valine metabolic process (GO:0006573)3.36856496
23translational initiation (GO:0006413)3.36276643
24ATP synthesis coupled proton transport (GO:0015986)3.35635960
25energy coupled proton transport, down electrochemical gradient (GO:0015985)3.35635960
26pyrimidine nucleotide catabolic process (GO:0006244)3.34828477
27cysteine metabolic process (GO:0006534)3.31470493
28protein targeting to mitochondrion (GO:0006626)3.22866055
29ribonucleoprotein complex biogenesis (GO:0022613)3.18690730
30COPI coating of Golgi vesicle (GO:0048205)3.16320369
31Golgi transport vesicle coating (GO:0048200)3.16320369
32SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.12536689
33cytochrome complex assembly (GO:0017004)3.12117480
34GDP-mannose metabolic process (GO:0019673)3.12074121
35nucleobase-containing small molecule interconversion (GO:0015949)3.11370790
36chaperone-mediated protein transport (GO:0072321)3.10669844
37protein complex disassembly (GO:0043241)3.09982194
38branched-chain amino acid catabolic process (GO:0009083)3.08045537
39deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.06246004
40NADH metabolic process (GO:0006734)3.05199844
41cotranslational protein targeting to membrane (GO:0006613)3.05162479
42respiratory electron transport chain (GO:0022904)3.04653783
43protein targeting to ER (GO:0045047)3.04438755
44oxidative phosphorylation (GO:0006119)3.03964635
45serine family amino acid biosynthetic process (GO:0009070)3.03394109
46protein targeting to membrane (GO:0006612)2.99761254
47deoxyribonucleotide catabolic process (GO:0009264)2.98040791
48protein localization to endoplasmic reticulum (GO:0070972)2.97933642
49aromatic amino acid family catabolic process (GO:0009074)2.96000461
50electron transport chain (GO:0022900)2.95676614
51pteridine-containing compound biosynthetic process (GO:0042559)2.94700485
52deoxyribose phosphate catabolic process (GO:0046386)2.93784149
53folic acid metabolic process (GO:0046655)2.90717254
54mitochondrial respiratory chain complex assembly (GO:0033108)2.90523910
55establishment of protein localization to mitochondrion (GO:0072655)2.90397890
56branched-chain amino acid metabolic process (GO:0009081)2.89919292
57protein complex biogenesis (GO:0070271)2.89709556
58macromolecular complex disassembly (GO:0032984)2.89093655
59GTP biosynthetic process (GO:0006183)2.88455314
60cellular component biogenesis (GO:0044085)2.87286355
61establishment of protein localization to endoplasmic reticulum (GO:0072599)2.85592290
62rRNA modification (GO:0000154)2.84040559
63negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.83010370
64regulation of mitochondrial translation (GO:0070129)2.82496935
65UTP biosynthetic process (GO:0006228)2.81940866
66ribosomal large subunit biogenesis (GO:0042273)2.81209394
67mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.80657570
68mitochondrial respiratory chain complex I assembly (GO:0032981)2.80657570
69NADH dehydrogenase complex assembly (GO:0010257)2.80657570
70Arp2/3 complex-mediated actin nucleation (GO:0034314)2.79750594
71peptidyl-histidine modification (GO:0018202)2.78955057
72purine nucleotide salvage (GO:0032261)2.78081347
73iron-sulfur cluster assembly (GO:0016226)2.77589690
74metallo-sulfur cluster assembly (GO:0031163)2.77589690
75proline biosynthetic process (GO:0006561)2.75543699
76pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.75099436
77sulfur amino acid catabolic process (GO:0000098)2.74382569
78tryptophan metabolic process (GO:0006568)2.74138531
79glyoxylate metabolic process (GO:0046487)2.73928572
80glycine metabolic process (GO:0006544)2.73827761
81protein localization to mitochondrion (GO:0070585)2.73056749
82antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.71004152
83amino acid salvage (GO:0043102)2.70840888
84L-methionine salvage (GO:0071267)2.70840888
85L-methionine biosynthetic process (GO:0071265)2.70840888
86antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.70060370
87antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.70060370
88maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.67890687
89intestinal cholesterol absorption (GO:0030299)2.67272057
90serine family amino acid metabolic process (GO:0009069)2.65612710
912-deoxyribonucleotide metabolic process (GO:0009394)2.65522480
92nucleoside diphosphate biosynthetic process (GO:0009133)2.65052774
93deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.64544478
94pentose metabolic process (GO:0019321)2.64056995
95pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.63357083
96formation of translation preinitiation complex (GO:0001731)2.62710482
97proline metabolic process (GO:0006560)2.62480682
98purine-containing compound salvage (GO:0043101)2.62038983
99protein retention in ER lumen (GO:0006621)2.61815561
100L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.61176202
101tryptophan catabolic process (GO:0006569)2.61148088
102indole-containing compound catabolic process (GO:0042436)2.61148088
103indolalkylamine catabolic process (GO:0046218)2.61148088
104ncRNA 3-end processing (GO:0043628)2.60256967
105negative regulation of myeloid cell apoptotic process (GO:0033033)2.59789016
106L-serine metabolic process (GO:0006563)2.59657179
107antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.59303441
108CTP metabolic process (GO:0046036)2.59207143
109CTP biosynthetic process (GO:0006241)2.59207143
110sulfur amino acid biosynthetic process (GO:0000097)2.56635257
111deoxyribose phosphate metabolic process (GO:0019692)2.56613390
112pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.56127162
113chaperone mediated protein folding requiring cofactor (GO:0051085)2.56125689
114translation (GO:0006412)2.56116445
115deoxyribonucleotide biosynthetic process (GO:0009263)2.55788262
116UDP-N-acetylglucosamine metabolic process (GO:0006047)2.55002839
117mitochondrial transport (GO:0006839)2.52427247
118UTP metabolic process (GO:0046051)2.51741596
119cellular metabolic compound salvage (GO:0043094)2.51668955
120aromatic amino acid family metabolic process (GO:0009072)2.51418122
121dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.51315814
122translational termination (GO:0006415)2.50605319
123transcription elongation from RNA polymerase III promoter (GO:0006385)2.49845721
124termination of RNA polymerase III transcription (GO:0006386)2.49845721
125viral transcription (GO:0019083)2.49757576
126NIK/NF-kappaB signaling (GO:0038061)2.47931778
127regulation of cellular amino acid metabolic process (GO:0006521)2.47408230
128regulation of necrotic cell death (GO:0010939)2.46852091
129regulation of mitochondrial membrane potential (GO:0051881)2.46732799
130exocrine pancreas development (GO:0031017)2.46404604
131response to interferon-beta (GO:0035456)2.46191936
132purine deoxyribonucleotide catabolic process (GO:0009155)2.44428610
133rRNA methylation (GO:0031167)2.44083166
134purine nucleobase biosynthetic process (GO:0009113)2.44011307
135GMP metabolic process (GO:0046037)2.43871438
136pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.42924797
137nucleotide-sugar metabolic process (GO:0009225)2.42572618
138pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.41922390
139pteridine-containing compound metabolic process (GO:0042558)2.41284565
140nuclear-transcribed mRNA catabolic process (GO:0000956)2.41104287
141rRNA processing (GO:0006364)2.40923454
142nucleoside salvage (GO:0043174)2.40563336
143bile acid biosynthetic process (GO:0006699)2.40064354
144aerobic respiration (GO:0009060)2.38708924
145ribosome biogenesis (GO:0042254)2.38458705
146COPII vesicle coating (GO:0048208)2.38395280
147protein maturation by protein folding (GO:0022417)2.37641680
148pantothenate metabolic process (GO:0015939)2.37499059
149base-excision repair, AP site formation (GO:0006285)2.36733859
150antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.34594851
151nucleotide salvage (GO:0043173)2.34197968
152pseudouridine synthesis (GO:0001522)2.33917619
153quinone biosynthetic process (GO:1901663)2.33619251
154ubiquinone biosynthetic process (GO:0006744)2.33619251
155S-adenosylmethionine metabolic process (GO:0046500)2.33596474
156mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.33426000
157negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.32396808
158telomere maintenance via semi-conservative replication (GO:0032201)2.30819988
159aldehyde catabolic process (GO:0046185)2.30128753
160guanosine-containing compound biosynthetic process (GO:1901070)2.28745769
161translational elongation (GO:0006414)2.27936139
162nucleobase biosynthetic process (GO:0046112)2.26990574
163antigen processing and presentation of endogenous antigen (GO:0019883)2.26525065
164fatty acid beta-oxidation (GO:0006635)2.25113419

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.77976969
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.32137842
3JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.31624436
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.22250096
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.13299877
6* MYC_18555785_ChIP-Seq_MESCs_Mouse2.93825107
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.91612735
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.79597606
9IRF8_22096565_ChIP-ChIP_GC-B_Human2.77354021
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.70373077
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.69118044
12TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.61847755
13* ETS1_20019798_ChIP-Seq_JURKAT_Human2.58645326
14RXR_22158963_ChIP-Seq_LIVER_Mouse2.53329432
15* EST1_17652178_ChIP-ChIP_JURKAT_Human2.52880520
16* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.41791084
17BP1_19119308_ChIP-ChIP_Hs578T_Human2.41485731
18CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.38358495
19SRF_21415370_ChIP-Seq_HL-1_Mouse2.36068695
20PPARA_22158963_ChIP-Seq_LIVER_Mouse2.33254412
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.31833053
22EGR1_23403033_ChIP-Seq_LIVER_Mouse2.31769299
23VDR_23849224_ChIP-Seq_CD4+_Human2.28866906
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.25839665
25PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.25363193
26PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.21548996
27* IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.11280183
28FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.07624702
29TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.05943739
30E2F7_22180533_ChIP-Seq_HELA_Human2.05271496
31DCP1A_22483619_ChIP-Seq_HELA_Human2.03510126
32SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.02004884
33* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.00882894
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.00783579
35* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.00204391
36* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.96531647
37* MYC_22102868_ChIP-Seq_BL_Human1.96230698
38FOXP3_21729870_ChIP-Seq_TREG_Human1.93072962
39* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.92557404
40* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.91683519
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.90629795
42LXR_22292898_ChIP-Seq_THP-1_Human1.87583307
43GABP_19822575_ChIP-Seq_HepG2_Human1.81078854
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.73924619
45SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.73043584
46SRY_22984422_ChIP-ChIP_TESTIS_Rat1.71647140
47CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.68834142
48* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.66253369
49* XRN2_22483619_ChIP-Seq_HELA_Human1.65005387
50* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.61672348
51STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.60739975
52CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.59814806
53DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.59054584
54TET1_21451524_ChIP-Seq_MESCs_Mouse1.58726924
55RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.57370134
56NOTCH1_21737748_ChIP-Seq_TLL_Human1.56163838
57PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54347150
58TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52927432
59CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.50128678
60HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.47212470
61ELK3_25401928_ChIP-Seq_HUVEC_Human1.45935174
62CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.44603553
63LXR_22158963_ChIP-Seq_LIVER_Mouse1.44213203
64YY1_21170310_ChIP-Seq_MESCs_Mouse1.43199437
65MYC_19079543_ChIP-ChIP_MESCs_Mouse1.43167134
66* RACK7_27058665_Chip-Seq_MCF-7_Human1.42716950
67GATA1_22025678_ChIP-Seq_K562_Human1.40723520
68* MAF_26560356_Chip-Seq_TH2_Human1.40289002
69FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.39640737
70ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39184194
71P68_20966046_ChIP-Seq_HELA_Human1.39048966
72SPI1_23547873_ChIP-Seq_NB4_Human1.38247432
73MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.38210739
74ELF1_20517297_ChIP-Seq_JURKAT_Human1.37529471
75BCL6_27268052_Chip-Seq_Bcells_Human1.36547736
76MAF_26560356_Chip-Seq_TH1_Human1.35846720
77IRF8_21731497_ChIP-ChIP_J774_Mouse1.35067920
78* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.33774231
79THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.32022670
80UTX_26944678_Chip-Seq_JUKART_Human1.30450595
81VDR_24763502_ChIP-Seq_THP-1_Human1.29374303
82* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.27345546
83BCOR_27268052_Chip-Seq_Bcells_Human1.26015692
84GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.23457706
85* SA1_27219007_Chip-Seq_ERYTHROID_Human1.22162799
86STAT4_19710469_ChIP-ChIP_TH1__Mouse1.21526742
87CTCF_26484167_Chip-Seq_Bcells_Mouse1.20726671
88* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.20526272
89NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.20346660
90MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.18569360
91MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.17776407
92CTCF_27219007_Chip-Seq_ERYTHROID_Human1.16250176
93RARG_19884340_ChIP-ChIP_MEFs_Mouse1.15816757
94ELK1_19687146_ChIP-ChIP_HELA_Human1.15025809
95CIITA_25753668_ChIP-Seq_RAJI_Human1.14744485
96GATA1_22383799_ChIP-Seq_G1ME_Mouse1.13817146
97TTF2_22483619_ChIP-Seq_HELA_Human1.13133396
98E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.12676406
99PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.12372404
100MYCN_18555785_ChIP-Seq_MESCs_Mouse1.12119174
101CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.10599976
102ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.10124158
103KLF4_18555785_ChIP-Seq_MESCs_Mouse1.08850446
104* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.08274508
105SCL_19346495_ChIP-Seq_HPC-7_Human1.07201297
106RUNX1_22412390_ChIP-Seq_EML_Mouse1.06945899
107ELK1_22589737_ChIP-Seq_MCF10A_Human1.06500385
108BRD4_27068464_Chip-Seq_AML-cells_Mouse1.05944258
109KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.04840192
110ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.04771100
111CTCF_21964334_Chip-Seq_Bcells_Human1.02728643
112LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.00837303
113MYB_21317192_ChIP-Seq_ERMYB_Mouse1.00441091
114FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.99803741
115GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.98652319
116CTCF_18555785_ChIP-Seq_MESCs_Mouse0.97958563
117LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.97608419
118* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.97081317
119SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.96981460
120TFEB_21752829_ChIP-Seq_HELA_Human0.96432854
121ZNF263_19887448_ChIP-Seq_K562_Human0.95417964
122STAT3_1855785_ChIP-Seq_MESCs_Mouse0.94294698
123HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.92604677
124AR_21909140_ChIP-Seq_LNCAP_Human0.92337955
125GATA2_22383799_ChIP-Seq_G1ME_Mouse0.92265928
126KDM5A_27292631_Chip-Seq_BREAST_Human0.91122792
127CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90073759
128PU.1_20513432_ChIP-Seq_Bcells_Mouse0.89808035
129POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.89756893
130ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.89719341
131MYC_18940864_ChIP-ChIP_HL60_Human0.89558077
132* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.88831562
133VDR_21846776_ChIP-Seq_THP-1_Human0.88173425
134SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.86950987
135CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.84470409

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system3.97883048
2MP0005365_abnormal_bile_salt3.70421685
3MP0003806_abnormal_nucleotide_metabolis3.32173517
4MP0005085_abnormal_gallbladder_physiolo3.11209987
5MP0005360_urolithiasis3.03255432
6MP0005083_abnormal_biliary_tract2.94385845
7MP0009840_abnormal_foam_cell2.60439253
8MP0001666_abnormal_nutrient_absorption2.56092557
9MP0003186_abnormal_redox_activity2.51633838
10MP0008875_abnormal_xenobiotic_pharmacok2.45531115
11MP0001835_abnormal_antigen_presentation2.25486264
12MP0003195_calcinosis2.21745160
13MP0002138_abnormal_hepatobiliary_system2.14561965
14MP0005220_abnormal_exocrine_pancreas2.07017064
15MP0006036_abnormal_mitochondrial_physio2.05655823
16MP0005451_abnormal_body_composition1.98939555
17MP0005671_abnormal_response_to1.92642188
18MP0001873_stomach_inflammation1.92601521
19MP0005332_abnormal_amino_acid1.91765706
20MP0000685_abnormal_immune_system1.82028416
21MP0003693_abnormal_embryo_hatching1.79966148
22MP0001764_abnormal_homeostasis1.79662580
23MP0009697_abnormal_copulation1.78447721
24MP0002163_abnormal_gland_morphology1.74370770
25MP0002396_abnormal_hematopoietic_system1.70974842
26MP0009785_altered_susceptibility_to1.70188082
27MP0003252_abnormal_bile_duct1.66554522
28MP0009643_abnormal_urine_homeostasis1.63204036
29MP0010329_abnormal_lipoprotein_level1.61742350
30MP0003303_peritoneal_inflammation1.58082573
31MP0003763_abnormal_thymus_physiology1.57848655
32MP0005084_abnormal_gallbladder_morpholo1.55271471
33MP0003191_abnormal_cellular_cholesterol1.55201385
34MP0003436_decreased_susceptibility_to1.55001027
35MP0004147_increased_porphyrin_level1.49795015
36MP0004019_abnormal_vitamin_homeostasis1.49733391
37MP0001853_heart_inflammation1.48772652
38MP0002693_abnormal_pancreas_physiology1.47449526
39MP0005319_abnormal_enzyme/_coenzyme1.44409562
40MP0000609_abnormal_liver_physiology1.43694925
41MP0008469_abnormal_protein_level1.42969290
42MP0005025_abnormal_response_to1.42625371
43MP0008260_abnormal_autophagy1.41196192
44MP0005636_abnormal_mineral_homeostasis1.36190340
45MP0004185_abnormal_adipocyte_glucose1.33951507
46MP0005058_abnormal_lysosome_morphology1.31341982
47MP0003868_abnormal_feces_composition1.29286568
48MP0000681_abnormal_thyroid_gland1.28650783
49MP0004947_skin_inflammation1.28222841
50MP0000678_abnormal_parathyroid_gland1.28165024
51MP0009333_abnormal_splenocyte_physiolog1.28135573
52MP0002132_abnormal_respiratory_system1.27995487
53MP0000703_abnormal_thymus_morphology1.27340674
54MP0002118_abnormal_lipid_homeostasis1.27249204
55MP0001986_abnormal_taste_sensitivity1.27050548
56MP0005501_abnormal_skin_physiology1.25601298
57MP0004043_abnormal_pH_regulation1.23756149
58MP0001727_abnormal_embryo_implantation1.22138374
59MP0000490_abnormal_crypts_of1.21860047
60MP0001800_abnormal_humoral_immune1.20503803
61MP0001845_abnormal_inflammatory_respons1.19575870
62MP0003656_abnormal_erythrocyte_physiolo1.18663159
63MP0002723_abnormal_immune_serum1.18477626
64MP0004858_abnormal_nervous_system1.16976935
65MP0002419_abnormal_innate_immunity1.16579110
66MP0005584_abnormal_enzyme/coenzyme_acti1.16543729
67MP0005000_abnormal_immune_tolerance1.16296686
68MP0002166_altered_tumor_susceptibility1.15852008
69MP0001944_abnormal_pancreas_morphology1.14482699
70MP0000343_altered_response_to1.14185512
71MP0003075_altered_response_to1.13788332
72MP0000465_gastrointestinal_hemorrhage1.13121205
73MP0006035_abnormal_mitochondrial_morpho1.12677954
74MP0002148_abnormal_hypersensitivity_rea1.12470980
75MP0005387_immune_system_phenotype1.11616518
76MP0001790_abnormal_immune_system1.11616518
77MP0002796_impaired_skin_barrier1.11002189
78MP0003718_maternal_effect1.10904707
79MP0009278_abnormal_bone_marrow1.10880093
80MP0010155_abnormal_intestine_physiology1.10187298
81MP0008058_abnormal_DNA_repair1.10024069
82MP0002452_abnormal_antigen_presenting1.08927022
83MP0005464_abnormal_platelet_physiology1.07746512
84MP0002420_abnormal_adaptive_immunity1.04356623
85MP0002019_abnormal_tumor_incidence1.04028971
86MP0000689_abnormal_spleen_morphology1.03416996
87MP0001881_abnormal_mammary_gland1.02889181
88MP0001819_abnormal_immune_cell1.01703390
89MP0004782_abnormal_surfactant_physiolog1.01618752
90MP0005379_endocrine/exocrine_gland_phen1.01581527
91MP0005166_decreased_susceptibility_to1.01493761
92MP0001533_abnormal_skeleton_physiology1.00801148
93MP0003123_paternal_imprinting1.00728736
94MP0001661_extended_life_span0.99960436
95MP0000313_abnormal_cell_death0.99140213
96MP0000598_abnormal_liver_morphology0.97828074
97MP0003724_increased_susceptibility_to0.97108320
98MP0000716_abnormal_immune_system0.95926933
99MP0009379_abnormal_foot_pigmentation0.95830306
100MP0002877_abnormal_melanocyte_morpholog0.93587081
101MP0002398_abnormal_bone_marrow0.93545402
102MP0001545_abnormal_hematopoietic_system0.92648507
103MP0003183_abnormal_peptide_metabolism0.92320753
104MP0005670_abnormal_white_adipose0.92028383
105MP0003111_abnormal_nucleus_morphology0.89983497
106MP0000604_amyloidosis0.88527994
107MP0003866_abnormal_defecation0.88381560
108MP0009763_increased_sensitivity_to0.88184565
109MP0004957_abnormal_blastocyst_morpholog0.87624534
110MP0002006_tumorigenesis0.87597341
111MP0002722_abnormal_immune_system0.87445908
112MP0002405_respiratory_system_inflammati0.87255149
113MP0009642_abnormal_blood_homeostasis0.87021443
114MP0002429_abnormal_blood_cell0.86846926
115MP0006082_CNS_inflammation0.86758738
116MP0002078_abnormal_glucose_homeostasis0.86387928
117MP0000858_altered_metastatic_potential0.84943014
118MP0001663_abnormal_digestive_system0.83836251
119MP0009764_decreased_sensitivity_to0.83255981
120MP0000613_abnormal_salivary_gland0.81824600
121MP0002876_abnormal_thyroid_physiology0.79869889
122MP0003077_abnormal_cell_cycle0.79832239
123MP0003786_premature_aging0.79560994
124MP0001756_abnormal_urination0.79419148
125MP0003172_abnormal_lysosome_physiology0.77955464
126MP0000015_abnormal_ear_pigmentation0.77490590
127MP0005666_abnormal_adipose_tissue0.77330358
128MP0002136_abnormal_kidney_physiology0.77054930
129MP0001919_abnormal_reproductive_system0.76809350
130MP0002009_preneoplasia0.74992426
131MP0008007_abnormal_cellular_replicative0.74484893
132MP0005075_abnormal_melanosome_morpholog0.74325002
133MP0005397_hematopoietic_system_phenotyp0.72846748

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)4.46611740
2Hepatic necrosis (HP:0002605)3.68133512
3Hepatocellular necrosis (HP:0001404)3.29428398
4Generalized aminoaciduria (HP:0002909)3.27073442
5Hypoglycemic coma (HP:0001325)3.26540689
6Abnormality of dicarboxylic acid metabolism (HP:0010995)3.21307534
7Dicarboxylic aciduria (HP:0003215)3.21307534
8Reduced antithrombin III activity (HP:0001976)3.16322554
9Microvesicular hepatic steatosis (HP:0001414)3.14117807
10Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.06941170
11Abnormality of fatty-acid metabolism (HP:0004359)2.99177055
12Decreased activity of mitochondrial respiratory chain (HP:0008972)2.96557836
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.96557836
14Chronic obstructive pulmonary disease (HP:0006510)2.93389584
15Obstructive lung disease (HP:0006536)2.93389584
16Ketosis (HP:0001946)2.91102665
17Type I transferrin isoform profile (HP:0003642)2.89815778
18Hyperglycinuria (HP:0003108)2.87857237
19Increased muscle lipid content (HP:0009058)2.85577206
20Increased intramyocellular lipid droplets (HP:0012240)2.81259236
21Abnormal protein N-linked glycosylation (HP:0012347)2.80118116
22Abnormal protein glycosylation (HP:0012346)2.80118116
23Abnormal glycosylation (HP:0012345)2.80118116
24Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.80118116
25Mitochondrial inheritance (HP:0001427)2.77129077
26Prolonged partial thromboplastin time (HP:0003645)2.75678660
27Abnormal number of erythroid precursors (HP:0012131)2.75598005
28Hypertensive crisis (HP:0100735)2.75125626
29Vacuolated lymphocytes (HP:0001922)2.74770949
30Hyperglycinemia (HP:0002154)2.74039672
31Intrahepatic cholestasis (HP:0001406)2.72305137
32Vertebral compression fractures (HP:0002953)2.70842941
33Abnormality of cells of the erythroid lineage (HP:0012130)2.70666902
34Lipid accumulation in hepatocytes (HP:0006561)2.69797659
35Abnormality of glycine metabolism (HP:0010895)2.67688716
36Abnormality of serine family amino acid metabolism (HP:0010894)2.67688716
37Acute encephalopathy (HP:0006846)2.67538038
38Ketoacidosis (HP:0001993)2.64484305
39Increased CSF lactate (HP:0002490)2.64365218
40Increased serum ferritin (HP:0003281)2.62668680
41Purpura (HP:0000979)2.62169627
42Acute necrotizing encephalopathy (HP:0006965)2.60484747
43Macrocytic anemia (HP:0001972)2.60172310
44Abnormal mitochondria in muscle tissue (HP:0008316)2.60099280
45Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.58131248
46Lactic acidosis (HP:0003128)2.57237169
47Lethargy (HP:0001254)2.55845114
48Gout (HP:0001997)2.55562974
49Eczematoid dermatitis (HP:0000976)2.55464309
50Cerebral edema (HP:0002181)2.54580320
51Aplasia/Hypoplasia of the sacrum (HP:0008517)2.54186904
52Abnormality of liposaccharide metabolism (HP:0010968)2.53391673
53Abnormality of glycosphingolipid metabolism (HP:0004343)2.53391673
54Abnormality of glycolipid metabolism (HP:0010969)2.53391673
55Nausea (HP:0002018)2.52986570
56Methylmalonic aciduria (HP:0012120)2.52469228
57Delayed CNS myelination (HP:0002188)2.52351216
58Increased serum lactate (HP:0002151)2.50995883
59Hypobetalipoproteinemia (HP:0003563)2.49145505
60Recurrent abscess formation (HP:0002722)2.49080216
61Abnormality of the intrinsic pathway (HP:0010989)2.48745803
62Abnormality of urine glucose concentration (HP:0011016)2.48376231
63Glycosuria (HP:0003076)2.48376231
64Increased hepatocellular lipid droplets (HP:0006565)2.47954376
65Abnormality of serum amino acid levels (HP:0003112)2.46396411
66Progressive muscle weakness (HP:0003323)2.44567482
67Abnormality of monocarboxylic acid metabolism (HP:0010996)2.44535581
683-Methylglutaconic aciduria (HP:0003535)2.44300338
69IgM deficiency (HP:0002850)2.41998135
70Fat malabsorption (HP:0002630)2.40836654
71Agammaglobulinemia (HP:0004432)2.40502552
72Renal Fanconi syndrome (HP:0001994)2.39704123
73Testicular atrophy (HP:0000029)2.39591070
74Hyperammonemia (HP:0001987)2.39504718
75Pallor (HP:0000980)2.36575198
76Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.35011277
77Hepatosplenomegaly (HP:0001433)2.32984090
78Mediastinal lymphadenopathy (HP:0100721)2.32529797
79Abnormality of macrophages (HP:0004311)2.29252673
80Conjugated hyperbilirubinemia (HP:0002908)2.27950297
81Steatorrhea (HP:0002570)2.26323281
82Xanthomatosis (HP:0000991)2.26153052
83Exertional dyspnea (HP:0002875)2.24538026
84Abnormality of alanine metabolism (HP:0010916)2.24092685
85Hyperalaninemia (HP:0003348)2.24092685
86Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.24092685
87Elevated erythrocyte sedimentation rate (HP:0003565)2.23426062
88Pancytopenia (HP:0001876)2.23423109
89Aplastic anemia (HP:0001915)2.21758571
90Reticulocytopenia (HP:0001896)2.21528331
91Hyperthyroidism (HP:0000836)2.21207061
92Metabolic acidosis (HP:0001942)2.21031294
93Rough bone trabeculation (HP:0100670)2.20006490
94Recurrent bacterial skin infections (HP:0005406)2.19542729
95Abnormality of methionine metabolism (HP:0010901)2.18191294
96Abnormality of T cell physiology (HP:0011840)2.17535139
97Absent rod-and cone-mediated responses on ERG (HP:0007688)2.17440042
98Late onset (HP:0003584)2.17342274
99Hyperlipoproteinemia (HP:0010980)2.16638538
100Respiratory failure (HP:0002878)2.14078267
101Seborrheic dermatitis (HP:0001051)2.11541374
102CNS demyelination (HP:0007305)2.10172976
103Increased IgM level (HP:0003496)2.09782855
104Meningitis (HP:0001287)2.09099244
105Microretrognathia (HP:0000308)2.08620008
106Progressive neurologic deterioration (HP:0002344)2.07854490
107Esophageal neoplasm (HP:0100751)2.07516890
108Neoplasm of head and neck (HP:0012288)2.07516890
109Colitis (HP:0002583)2.07364325
110Abnormality of aspartate family amino acid metabolism (HP:0010899)2.07020144
111Respiratory difficulties (HP:0002880)2.06183567
112Increased cerebral lipofuscin (HP:0011813)2.05098735
113Rhabdomyolysis (HP:0003201)2.04214824
114Exercise intolerance (HP:0003546)2.04112937
115Emotional lability (HP:0000712)2.03389719
116Increased neuronal autofluorescent lipopigment (HP:0002074)2.03149658
117Hyperbilirubinemia (HP:0002904)2.01680232
118Beaking of vertebral bodies (HP:0004568)1.99876118
119Poor head control (HP:0002421)1.98791506
120Abnormality of the heme biosynthetic pathway (HP:0010472)1.98479070
121Gastrointestinal stroma tumor (HP:0100723)1.97680466
122Megaloblastic anemia (HP:0001889)1.97301998
123Brushfield spots (HP:0001088)1.97035155
124Prolonged neonatal jaundice (HP:0006579)1.96441066
125Progressive macrocephaly (HP:0004481)1.95531938
126Petechiae (HP:0000967)1.94731489
127Thrombocytosis (HP:0001894)1.94421825
128Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.94168110
129Systemic lupus erythematosus (HP:0002725)1.93847462
130Dysostosis multiplex (HP:0000943)1.92638052
131Microcytic anemia (HP:0001935)1.92012826
132Abnormality of iron homeostasis (HP:0011031)1.91870805
133Cellulitis (HP:0100658)1.91730901
134Abnormality of the common coagulation pathway (HP:0010990)1.91434854
135Hyperphosphaturia (HP:0003109)1.91347291
136Ragged-red muscle fibers (HP:0003200)1.91342994
137Hypoglycemic seizures (HP:0002173)1.91299960
138Recurrent viral infections (HP:0004429)1.91011514
139Hyperparathyroidism (HP:0000843)1.90112877
140Pancreatitis (HP:0001733)1.89984864
141Spastic paraparesis (HP:0002313)1.89889642
142Vomiting (HP:0002013)1.89823595
143Gastrointestinal inflammation (HP:0004386)1.89418625
144Abnormality of pyrimidine metabolism (HP:0004353)1.89417594
145Cerebral palsy (HP:0100021)1.85048117
146Myopathic facies (HP:0002058)1.83176858
147Acute hepatic failure (HP:0006554)1.81353328
148Multiple enchondromatosis (HP:0005701)1.81115230
149Urticaria (HP:0001025)1.79439121
150Abnormal trabecular bone morphology (HP:0100671)1.76051876
151Loss of speech (HP:0002371)1.75843128
152Orthostatic hypotension (HP:0001278)1.75183238
153Inflammation of the large intestine (HP:0002037)1.72179228
154Recurrent fungal infections (HP:0002841)1.71977723
155Truncus arteriosus (HP:0001660)1.69004719
156Skin rash (HP:0000988)1.68976591
157Granulocytopenia (HP:0001913)1.68785356

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.75531414
2NME24.32355169
3BCKDK4.15859701
4ERN13.40131457
5TESK12.68916282
6TRIB32.63221210
7BUB12.60342218
8EIF2AK32.44761143
9MUSK2.06847305
10VRK22.03194829
11MAPK151.99605914
12PIM21.94102365
13WEE11.86187996
14TLK11.86017417
15PRPF4B1.82002375
16VRK11.78237060
17MAP4K11.76224640
18FLT31.71788054
19DYRK31.67986916
20TBK11.67568710
21SCYL21.65642950
22SMG11.65398230
23TYK21.61332301
24RPS6KA41.60979600
25TEC1.60251210
26ARAF1.57745439
27CAMKK21.56223911
28KIT1.56005504
29EIF2AK11.55796853
30IRAK31.52709105
31LIMK11.45452891
32ACVR1B1.43203121
33MAP2K31.43041742
34IKBKE1.41055754
35KDR1.40344064
36RIPK41.39532762
37MAP3K31.32800303
38ILK1.30926754
39ZAP701.30394976
40IRAK41.28143524
41MAPKAPK31.26224539
42NLK1.23685702
43PLK41.20542296
44BTK1.18739599
45TGFBR21.18268424
46MAP3K141.12792263
47TAOK31.12712029
48PIK3CG1.05729835
49PASK1.02047064
50NME11.01836155
51TESK21.00949738
52IKBKB1.00351606
53AURKA1.00078780
54BLK0.99361129
55BRSK20.95806637
56MAP3K120.94514765
57JAK30.93653522
58PKN20.91026739
59INSRR0.89686162
60SRPK10.88235984
61CSF1R0.87620222
62LRRK20.83796370
63PINK10.82849486
64MAP3K130.82712104
65MAP3K110.82483063
66MAP3K10.82379628
67TXK0.82242745
68CDK80.82097229
69SIK10.81138612
70BRAF0.77674542
71ZAK0.77347299
72PAK40.75738461
73RPS6KB20.75193390
74ABL20.74425699
75IRAK10.74415112
76DAPK10.74398420
77PBK0.73695250
78MST40.73530571
79EPHA20.71595475
80PDK20.70399258
81IRAK20.69421099
82SYK0.68764037
83MAPKAPK50.67340662
84FGFR40.67304109
85DAPK30.67303266
86FES0.66406103
87PIM10.65046850
88TIE10.63537159
89TAOK10.62764763
90MAP2K20.62317794
91PRKCI0.61739190
92PAK10.61665575
93PDPK10.59309565
94TNK20.58922406
95MAP3K80.57186863
96ICK0.56944838
97MAPK110.56688527
98STK100.56592892
99LYN0.55649770
100CDK190.54474927
101RPS6KA50.53798609
102EIF2AK20.52317313
103CDK70.52037887
104CCNB10.51661301
105MAP2K60.50490420
106HIPK20.50221344
107MST1R0.50193026
108MYLK0.48708548
109TNIK0.47849153
110NEK90.47520015
111EEF2K0.46327657
112CSK0.43922871
113TGFBR10.43329321
114MAP3K50.42808245
115RAF10.42588397
116JAK10.42534215
117PRKG20.42468759
118PRKD20.41637256
119CSNK2A10.41453738
120LCK0.41279961
121CDK40.40265814
122AURKB0.40255332
123GRK60.39910337
124FRK0.39739555
125CHUK0.39330354
126NEK10.38830883
127CAMK2G0.38549307
128CSNK2A20.37819471
129MAP3K70.37771537
130PDK10.35847876
131MAPKAPK20.35659118
132MAPK120.35234375
133OBSCN0.34237945
134PRKCD0.34028778
135AKT20.33701507
136ATR0.32361361
137HCK0.31080327
138TAOK20.30481746
139BMPR20.30058084
140MAPK40.29859115
141GRK10.29716019
142JAK20.29606245
143RPS6KL10.27989806
144RPS6KC10.27989806

Predicted pathways (KEGG)

RankGene SetZ-score
1Protein export_Homo sapiens_hsa030603.50191785
2Folate biosynthesis_Homo sapiens_hsa007902.86925081
3Ribosome_Homo sapiens_hsa030102.44132210
4Proteasome_Homo sapiens_hsa030502.32798057
5Maturity onset diabetes of the young_Homo sapiens_hsa049502.22861524
6RNA polymerase_Homo sapiens_hsa030202.19432727
7Primary bile acid biosynthesis_Homo sapiens_hsa001202.09993452
8Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.07220633
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.98262189
10DNA replication_Homo sapiens_hsa030301.95781539
11Pyrimidine metabolism_Homo sapiens_hsa002401.92685761
12Selenocompound metabolism_Homo sapiens_hsa004501.90799668
13Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.90528253
14Drug metabolism - other enzymes_Homo sapiens_hsa009831.84824585
15Caffeine metabolism_Homo sapiens_hsa002321.82731616
16Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.77239139
17Pentose and glucuronate interconversions_Homo sapiens_hsa000401.75406514
18Peroxisome_Homo sapiens_hsa041461.75295915
19Fatty acid degradation_Homo sapiens_hsa000711.69659366
20Sulfur metabolism_Homo sapiens_hsa009201.65041384
21Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.61673419
22Allograft rejection_Homo sapiens_hsa053301.58646704
23Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.58042645
24Sulfur relay system_Homo sapiens_hsa041221.57833292
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.52621740
26Autoimmune thyroid disease_Homo sapiens_hsa053201.51538954
27Propanoate metabolism_Homo sapiens_hsa006401.47812335
28Non-homologous end-joining_Homo sapiens_hsa034501.47386041
29Base excision repair_Homo sapiens_hsa034101.45904248
30Systemic lupus erythematosus_Homo sapiens_hsa053221.40671362
31Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.39833064
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.38855503
33Graft-versus-host disease_Homo sapiens_hsa053321.38652915
34Homologous recombination_Homo sapiens_hsa034401.38385260
35Oxidative phosphorylation_Homo sapiens_hsa001901.36596411
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.36200574
37Tryptophan metabolism_Homo sapiens_hsa003801.31868420
38Pentose phosphate pathway_Homo sapiens_hsa000301.27260833
39Asthma_Homo sapiens_hsa053101.27156891
40Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.26666147
41Parkinsons disease_Homo sapiens_hsa050121.23581361
42beta-Alanine metabolism_Homo sapiens_hsa004101.23182864
43Mismatch repair_Homo sapiens_hsa034301.21300959
44Chemical carcinogenesis_Homo sapiens_hsa052041.19289304
45Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.13841999
46Vibrio cholerae infection_Homo sapiens_hsa051101.13821538
47Histidine metabolism_Homo sapiens_hsa003401.12823779
48Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.11243764
49Glutathione metabolism_Homo sapiens_hsa004801.09988010
50Other glycan degradation_Homo sapiens_hsa005111.06393724
51Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.05937676
52Starch and sucrose metabolism_Homo sapiens_hsa005001.01579450
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.01048987
54Regulation of autophagy_Homo sapiens_hsa041401.00233253
55Butanoate metabolism_Homo sapiens_hsa006500.99981543
56Type I diabetes mellitus_Homo sapiens_hsa049400.99626474
57Purine metabolism_Homo sapiens_hsa002300.99034941
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.98660138
59Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.97739205
60Fat digestion and absorption_Homo sapiens_hsa049750.97503557
61Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.97321672
62Carbon metabolism_Homo sapiens_hsa012000.96662430
63Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.96265300
64Leishmaniasis_Homo sapiens_hsa051400.94544407
65Galactose metabolism_Homo sapiens_hsa000520.94306114
66N-Glycan biosynthesis_Homo sapiens_hsa005100.93859020
67Nucleotide excision repair_Homo sapiens_hsa034200.93782472
68One carbon pool by folate_Homo sapiens_hsa006700.93097898
69Arginine and proline metabolism_Homo sapiens_hsa003300.92214113
70Vitamin digestion and absorption_Homo sapiens_hsa049770.92103178
71Biosynthesis of amino acids_Homo sapiens_hsa012300.91611741
72Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.91228561
73Fatty acid metabolism_Homo sapiens_hsa012120.89518065
74Complement and coagulation cascades_Homo sapiens_hsa046100.89375522
75Fatty acid elongation_Homo sapiens_hsa000620.88175794
76Metabolic pathways_Homo sapiens_hsa011000.87495978
77Pyruvate metabolism_Homo sapiens_hsa006200.86602556
78B cell receptor signaling pathway_Homo sapiens_hsa046620.86466284
79Steroid hormone biosynthesis_Homo sapiens_hsa001400.86289940
80Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.86284760
81Toll-like receptor signaling pathway_Homo sapiens_hsa046200.86157165
82Viral myocarditis_Homo sapiens_hsa054160.85988701
83Herpes simplex infection_Homo sapiens_hsa051680.85594447
84Collecting duct acid secretion_Homo sapiens_hsa049660.85524316
85Shigellosis_Homo sapiens_hsa051310.85448466
86Retinol metabolism_Homo sapiens_hsa008300.84252942
87Rheumatoid arthritis_Homo sapiens_hsa053230.79990837
88Epstein-Barr virus infection_Homo sapiens_hsa051690.79918211
892-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.77537672
90Acute myeloid leukemia_Homo sapiens_hsa052210.76790887
91Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.76595143
92NF-kappa B signaling pathway_Homo sapiens_hsa040640.76552636
93Phenylalanine metabolism_Homo sapiens_hsa003600.75875316
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.75535824
95Primary immunodeficiency_Homo sapiens_hsa053400.70101402
96Huntingtons disease_Homo sapiens_hsa050160.70039516
97Bladder cancer_Homo sapiens_hsa052190.69924992
98Spliceosome_Homo sapiens_hsa030400.69086011
99Vitamin B6 metabolism_Homo sapiens_hsa007500.67683149
100Intestinal immune network for IgA production_Homo sapiens_hsa046720.67505604
101Hematopoietic cell lineage_Homo sapiens_hsa046400.67130660
102Cyanoamino acid metabolism_Homo sapiens_hsa004600.66919815
103Salmonella infection_Homo sapiens_hsa051320.64870338
104Tyrosine metabolism_Homo sapiens_hsa003500.64560011
105Alzheimers disease_Homo sapiens_hsa050100.64300375
106Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.64220702
107Fructose and mannose metabolism_Homo sapiens_hsa000510.64099693
108Prion diseases_Homo sapiens_hsa050200.61868618
109Apoptosis_Homo sapiens_hsa042100.61756843
110Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.60444333
111Legionellosis_Homo sapiens_hsa051340.59438404
112Tuberculosis_Homo sapiens_hsa051520.58810074
113Lysosome_Homo sapiens_hsa041420.55120019
114PPAR signaling pathway_Homo sapiens_hsa033200.54176080
115Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.53928501
116Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.53751277
117Cardiac muscle contraction_Homo sapiens_hsa042600.53311449
118Osteoclast differentiation_Homo sapiens_hsa043800.53158905
119Arginine biosynthesis_Homo sapiens_hsa002200.53088804
120Antigen processing and presentation_Homo sapiens_hsa046120.52438466
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.52051598
122RNA transport_Homo sapiens_hsa030130.50325125
123RNA degradation_Homo sapiens_hsa030180.49623130
124ABC transporters_Homo sapiens_hsa020100.49340708
125Measles_Homo sapiens_hsa051620.49184997
126Alcoholism_Homo sapiens_hsa050340.46468434
127Viral carcinogenesis_Homo sapiens_hsa052030.45868062
128Influenza A_Homo sapiens_hsa051640.45452651
129Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45257595
130Staphylococcus aureus infection_Homo sapiens_hsa051500.45016546
131Phagosome_Homo sapiens_hsa041450.43682223
132Glycosaminoglycan degradation_Homo sapiens_hsa005310.43502268
133Glycerolipid metabolism_Homo sapiens_hsa005610.43229904
134Non-small cell lung cancer_Homo sapiens_hsa052230.42618965
135Linoleic acid metabolism_Homo sapiens_hsa005910.42051331
136alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.40974565
137Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.40068914
138HTLV-I infection_Homo sapiens_hsa051660.36560771
139T cell receptor signaling pathway_Homo sapiens_hsa046600.35577793

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