KANSL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1histone H3-K36 demethylation (GO:0070544)3.98137426
2carnitine shuttle (GO:0006853)3.84888816
3carnitine transmembrane transport (GO:1902603)3.84053975
4carnitine transport (GO:0015879)3.77875393
5amino-acid betaine transport (GO:0015838)3.77875393
6piRNA metabolic process (GO:0034587)3.73230322
7sodium ion export (GO:0071436)3.59661209
8regulation of fatty acid beta-oxidation (GO:0031998)3.55497397
9fatty acid transmembrane transport (GO:1902001)3.51831516
10interkinetic nuclear migration (GO:0022027)3.49896712
11macroautophagy (GO:0016236)3.44651060
12histone H3-K9 modification (GO:0061647)3.44497389
13histone H3-K9 methylation (GO:0051567)3.41869364
14mitotic sister chromatid cohesion (GO:0007064)3.41860991
15regulation of RNA export from nucleus (GO:0046831)3.39493062
16histone H3-K9 demethylation (GO:0033169)3.34257749
17negative regulation of erythrocyte differentiation (GO:0045647)3.33340151
18positive regulation of fatty acid beta-oxidation (GO:0032000)3.31789875
19synaptonemal complex assembly (GO:0007130)3.31635312
20negative regulation of potassium ion transmembrane transport (GO:1901380)3.31395247
21histone H3-K4 methylation (GO:0051568)3.29375240
22histone H3-K4 trimethylation (GO:0080182)3.28806636
23synaptonemal complex organization (GO:0070193)3.27302446
24regulation of histone H3-K27 methylation (GO:0061085)3.24670746
25lysine catabolic process (GO:0006554)3.24581780
26lysine metabolic process (GO:0006553)3.24581780
27positive regulation of male gonad development (GO:2000020)3.23561503
28histone H4 deacetylation (GO:0070933)3.20837036
29histone lysine methylation (GO:0034968)3.20816869
30positive regulation of gene expression, epigenetic (GO:0045815)3.19489193
31regulation of nuclear cell cycle DNA replication (GO:0033262)3.19267116
32negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.18427268
33regulation of NFAT protein import into nucleus (GO:0051532)3.17625020
34alpha-linolenic acid metabolic process (GO:0036109)3.17052369
35cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.16550841
36histone deubiquitination (GO:0016578)3.16028620
37regulation of fatty acid oxidation (GO:0046320)3.14507265
38cilium or flagellum-dependent cell motility (GO:0001539)3.13218077
39negative regulation of histone methylation (GO:0031061)3.12395014
40male meiosis (GO:0007140)3.07593387
41regulation of protein polyubiquitination (GO:1902914)3.06977914
42dicarboxylic acid biosynthetic process (GO:0043650)3.05427154
43myofibril assembly (GO:0030239)3.05001826
44fibroblast migration (GO:0010761)3.00993603
45definitive hemopoiesis (GO:0060216)3.00427721
46cell communication by electrical coupling (GO:0010644)2.98774680
47positive regulation of histone deacetylation (GO:0031065)2.98627268
482-oxoglutarate metabolic process (GO:0006103)2.98390619
49regulation of nucleobase-containing compound transport (GO:0032239)2.94070071
50regulation of meiosis I (GO:0060631)2.94004282
51peptidyl-lysine dimethylation (GO:0018027)2.92392247
52fusion of sperm to egg plasma membrane (GO:0007342)2.91215595
53NLS-bearing protein import into nucleus (GO:0006607)2.90754833
54histone lysine demethylation (GO:0070076)2.90605033
55activation of protein kinase A activity (GO:0034199)2.89615082
56coronary vasculature morphogenesis (GO:0060977)2.88654962
57intracellular estrogen receptor signaling pathway (GO:0030520)2.85061754
58positive regulation of glycogen biosynthetic process (GO:0045725)2.84765345
59quaternary ammonium group transport (GO:0015697)2.83730027
60histone demethylation (GO:0016577)2.82250862
61positive regulation of fatty acid oxidation (GO:0046321)2.80704675
62plasma membrane repair (GO:0001778)2.79628766
63positive regulation of glycogen metabolic process (GO:0070875)2.77434813
64fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.74782744
65regulation of cholesterol homeostasis (GO:2000188)2.74774404
66peptidyl-lysine trimethylation (GO:0018023)2.74107001
67intra-S DNA damage checkpoint (GO:0031573)2.72458538
68negative regulation of cell size (GO:0045792)2.69314232
69creatine metabolic process (GO:0006600)2.68829695
70histone H3 deacetylation (GO:0070932)2.68536715
71gonadal mesoderm development (GO:0007506)2.68165946
72N-terminal protein amino acid acetylation (GO:0006474)2.66928227
73nuclear pore organization (GO:0006999)2.64417931
74positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.62793804
75histone methylation (GO:0016571)2.62204347
76embryonic hemopoiesis (GO:0035162)2.60117505
77tricarboxylic acid cycle (GO:0006099)2.58111011
78motile cilium assembly (GO:0044458)2.58007998
79cardiac myofibril assembly (GO:0055003)2.57484093
80layer formation in cerebral cortex (GO:0021819)2.56054127
81stress granule assembly (GO:0034063)2.54428033
82regulation of histone H3-K4 methylation (GO:0051569)2.54406701
83regulation of p38MAPK cascade (GO:1900744)2.53732557
84plasma membrane fusion (GO:0045026)2.52772581
85nucleus localization (GO:0051647)2.52066031
86peptidyl-lysine methylation (GO:0018022)2.49768002
87cellular sodium ion homeostasis (GO:0006883)2.49459202
88alanine transport (GO:0032328)2.49270192
89regulation of male gonad development (GO:2000018)2.48797814
90positive regulation of Rab GTPase activity (GO:0032851)2.47570652
91regulation of Rab GTPase activity (GO:0032313)2.47570652
92actin-myosin filament sliding (GO:0033275)2.46881258
93muscle filament sliding (GO:0030049)2.46881258
94protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.46445651
95mannose metabolic process (GO:0006013)2.46424559
96oxaloacetate metabolic process (GO:0006107)2.46024473
97dosage compensation (GO:0007549)2.45932464
98tricarboxylic acid metabolic process (GO:0072350)2.44247385
99adherens junction assembly (GO:0034333)2.43556187
100glial cell proliferation (GO:0014009)2.43352312
101valine metabolic process (GO:0006573)2.43158456
1023-UTR-mediated mRNA stabilization (GO:0070935)2.42809856
103phospholipid homeostasis (GO:0055091)2.42696428
104intracellular lipid transport (GO:0032365)2.42665831
105aspartate family amino acid catabolic process (GO:0009068)2.42656979
106succinate metabolic process (GO:0006105)2.42299328
107protein demethylation (GO:0006482)2.41162397
108protein dealkylation (GO:0008214)2.41162397
109positive regulation of CREB transcription factor activity (GO:0032793)2.40984918
110regulation of protein deacetylation (GO:0090311)2.40565377
111positive regulation of lipid catabolic process (GO:0050996)2.40459538
112regulation of cholesterol storage (GO:0010885)2.40356310
113embryonic camera-type eye morphogenesis (GO:0048596)2.39166754
114cytoplasmic mRNA processing body assembly (GO:0033962)2.38749828
115arginine catabolic process (GO:0006527)2.37956602
116positive regulation of DNA-dependent DNA replication (GO:2000105)2.37649650
117poly(A)+ mRNA export from nucleus (GO:0016973)2.36358255
118positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.36242767
119urea metabolic process (GO:0019627)2.35225124
120urea cycle (GO:0000050)2.35225124
121snRNA transcription (GO:0009301)2.35076349
122regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.35022135
123striated muscle atrophy (GO:0014891)2.34817486
124monoubiquitinated protein deubiquitination (GO:0035520)2.33264537
125sperm motility (GO:0030317)2.32728014
126carnitine metabolic process (GO:0009437)2.31734315
127regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.31663732
128sarcoplasmic reticulum calcium ion transport (GO:0070296)2.31323440
129protein K48-linked deubiquitination (GO:0071108)2.31172421
130peptidyl-threonine phosphorylation (GO:0018107)2.31170787
131skeletal muscle adaptation (GO:0043501)2.31107263
132apoptotic cell clearance (GO:0043277)2.31089763
133amino-acid betaine metabolic process (GO:0006577)2.30901282
134chromatin silencing (GO:0006342)2.30011351
135regulation of ARF protein signal transduction (GO:0032012)2.29536022
136regulation of ARF GTPase activity (GO:0032312)2.29114284
137phosphatidylinositol dephosphorylation (GO:0046856)2.28216176
138actin-mediated cell contraction (GO:0070252)2.28159914
139hippo signaling (GO:0035329)2.28041927
140pericardium development (GO:0060039)2.27846136
141positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.25308102
142sex differentiation (GO:0007548)2.25187466
143sister chromatid cohesion (GO:0007062)2.24726536
144positive regulation of myotube differentiation (GO:0010831)2.24661452
145positive regulation of natural killer cell differentiation (GO:0032825)2.24225232
146phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.23002929
147fatty acid homeostasis (GO:0055089)2.22677416
148cell communication involved in cardiac conduction (GO:0086065)2.22537399
149cellular potassium ion homeostasis (GO:0030007)2.22211293
150erythrocyte development (GO:0048821)2.21936193
151negative regulation of histone modification (GO:0031057)2.21778007
152nuclear pore complex assembly (GO:0051292)2.21012542
153kynurenine metabolic process (GO:0070189)2.20832033
154negative regulation of fatty acid transport (GO:2000192)2.20015765
155sex determination (GO:0007530)2.19903513
156regulation of histone methylation (GO:0031060)2.19897033
157phospholipid dephosphorylation (GO:0046839)2.19522607
158growth hormone receptor signaling pathway (GO:0060396)2.19501670
159positive regulation of receptor recycling (GO:0001921)2.19267512
160regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.19103320
161NADH metabolic process (GO:0006734)2.18357843
162positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.18183392
163regulation of gamma-delta T cell differentiation (GO:0045586)2.18114786
164proline transport (GO:0015824)2.17917274
165establishment of nucleus localization (GO:0040023)2.17648921
166CDP-diacylglycerol biosynthetic process (GO:0016024)2.17543595
167planar cell polarity pathway involved in neural tube closure (GO:0090179)2.17099035
168positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.16986018
169embryonic retina morphogenesis in camera-type eye (GO:0060059)2.16915315
170camera-type eye morphogenesis (GO:0048593)2.16740400
171mRNA stabilization (GO:0048255)2.16732760
172RNA stabilization (GO:0043489)2.16732760
173hepatocyte apoptotic process (GO:0097284)2.16648373
174regulation of tight junction assembly (GO:2000810)2.16328973
175cardiac muscle contraction (GO:0060048)2.16026228
176positive regulation of fatty acid metabolic process (GO:0045923)2.15906106
177insulin-like growth factor receptor signaling pathway (GO:0048009)2.15079669
178spermatid development (GO:0007286)2.14264191
179regulation of sequestering of triglyceride (GO:0010889)2.13969858
180reverse cholesterol transport (GO:0043691)2.13603983
181positive regulation of protein kinase C signaling (GO:0090037)2.12975934
182positive regulation of macroautophagy (GO:0016239)2.12428046
183SMAD protein complex assembly (GO:0007183)2.11580154

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.81382145
2NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.53042245
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.38021474
4RXR_22158963_ChIP-Seq_LIVER_Mouse2.27302455
5LXR_22158963_ChIP-Seq_LIVER_Mouse2.22134872
6PPARA_22158963_ChIP-Seq_LIVER_Mouse2.20923796
7EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.15278617
8KDM2B_26808549_Chip-Seq_DND41_Human2.03077407
9ZNF263_19887448_ChIP-Seq_K562_Human2.01617752
10VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.95916721
11KDM2B_26808549_Chip-Seq_SUP-B15_Human1.95131501
12NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.94809967
13RBPJ_22232070_ChIP-Seq_NCS_Mouse1.93173082
14SALL1_21062744_ChIP-ChIP_HESCs_Human1.89464771
15TCF7_22412390_ChIP-Seq_EML_Mouse1.88407027
16SCL_19346495_ChIP-Seq_HPC-7_Human1.86904549
17E2F7_22180533_ChIP-Seq_HELA_Human1.81548122
18THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.78073253
19FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.76374436
20EZH2_22144423_ChIP-Seq_EOC_Human1.74465308
21KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.74136494
22CLOCK_20551151_ChIP-Seq_293T_Human1.73373358
23EGR1_19374776_ChIP-ChIP_THP-1_Human1.71442576
24DROSHA_22980978_ChIP-Seq_HELA_Human1.71255062
25CTNNB1_20460455_ChIP-Seq_HCT116_Human1.70685793
26STAT6_21828071_ChIP-Seq_BEAS2B_Human1.68081607
27KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.67191678
28MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.65425366
29TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.64792320
30KDM2B_26808549_Chip-Seq_K562_Human1.64503301
31GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.62093458
32DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.60283574
33STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.60188879
34TBX20_22080862_ChIP-Seq_HEART_Mouse1.57525510
35TBX20_22328084_ChIP-Seq_HEART_Mouse1.57525510
36EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.56177933
37NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.53749918
38LXR_22292898_ChIP-Seq_THP-1_Human1.53345785
39TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.51052222
40TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.50071447
41FOXA2_19822575_ChIP-Seq_HepG2_Human1.47336715
42ESR2_21235772_ChIP-Seq_MCF-7_Human1.47022612
43MYC_22102868_ChIP-Seq_BL_Human1.45629034
44PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.45482497
45STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.40552333
46WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.40325679
47ZFP281_18757296_ChIP-ChIP_E14_Mouse1.40257986
48SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.37491532
49SPI1_23127762_ChIP-Seq_K562_Human1.36345346
50BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.35362258
51KDM2B_26808549_Chip-Seq_JURKAT_Human1.33193998
52GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.32483756
53CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.32276849
54TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.31139520
55IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.30540739
56P300_27058665_Chip-Seq_ZR-75-30cells_Human1.30287610
57EP300_21415370_ChIP-Seq_HL-1_Mouse1.28692459
58ZFP281_27345836_Chip-Seq_ESCs_Mouse1.28214593
59RUNX_20019798_ChIP-Seq_JUKART_Human1.27681242
60FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.26918816
61PKCTHETA_26484144_Chip-Seq_BREAST_Human1.26703348
62RARB_27405468_Chip-Seq_BRAIN_Mouse1.26649595
63SOX9_24532713_ChIP-Seq_HFSC_Mouse1.26376984
64VDR_21846776_ChIP-Seq_THP-1_Human1.23982161
65RUNX1_27514584_Chip-Seq_MCF-7_Human1.22096913
66CREB1_26743006_Chip-Seq_LNCaP_Human1.17292127
67KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.17194511
68ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.16906505
69CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.15737838
70GATA1_19941826_ChIP-Seq_K562_Human1.15318883
71GATA1_22383799_ChIP-Seq_G1ME_Mouse1.14487659
72MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.14469772
73RACK7_27058665_Chip-Seq_MCF-7_Human1.12477355
74FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.12131605
75TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.11459862
76WT1_19549856_ChIP-ChIP_CCG9911_Human1.10985724
77ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.10588241
78IKZF1_21737484_ChIP-ChIP_HCT116_Human1.09631174
79RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.09597179
80SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.09205337
81RARG_19884340_ChIP-ChIP_MEFs_Mouse1.08103431
82EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.07652847
83GATA1_19941827_ChIP-Seq_MEL_Mouse1.07412777
84ELK3_25401928_ChIP-Seq_HUVEC_Human1.07297325
85WT1_25993318_ChIP-Seq_PODOCYTE_Human1.06628591
86BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.06574069
87TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.04839652
88TP53_16413492_ChIP-PET_HCT116_Human1.04536418
89FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.03937880
90P68_20966046_ChIP-Seq_HELA_Human1.03683393
91TP53_23651856_ChIP-Seq_MEFs_Mouse1.03015063
92TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02693608
93SMC4_20622854_ChIP-Seq_HELA_Human1.02240732
94MAF_26560356_Chip-Seq_TH1_Human1.00541994
95CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.99682362
96GATA1_19941827_ChIP-Seq_MEL86_Mouse0.99532175
97E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.98163700
98FOXO3_23340844_ChIP-Seq_DLD1_Human0.98030259
99MITF_21258399_ChIP-Seq_MELANOMA_Human0.97167505
100CTCF_27219007_Chip-Seq_Bcells_Human0.97033504
101GATA1_22025678_ChIP-Seq_K562_Human0.96544231
102TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.96488549
103TET1_21490601_ChIP-Seq_MESCs_Mouse0.94886385
104NFIB_24661679_ChIP-Seq_LUNG_Mouse0.94685187
105TP53_22127205_ChIP-Seq_IMR90_Human0.94606806
106SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.94536161
107ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.94137484
108KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.92712166
109ESR1_21235772_ChIP-Seq_MCF-7_Human0.92341942
110MAF_26560356_Chip-Seq_TH2_Human0.91508155
111DNAJC2_21179169_ChIP-ChIP_NT2_Human0.91350850
112RUNX1_22412390_ChIP-Seq_EML_Mouse0.90788977
113FOXM1_23109430_ChIP-Seq_U2OS_Human0.90691659
114MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.89984964
115ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.89219160
116GATA2_21666600_ChIP-Seq_HMVEC_Human0.89089121
117GATA4_21415370_ChIP-Seq_HL-1_Mouse0.88877097
118ESR1_20079471_ChIP-ChIP_T-47D_Human0.88372397
119TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.87483500
120ISL1_27105846_Chip-Seq_CPCs_Mouse0.87262466
121ELF1_20517297_ChIP-Seq_JURKAT_Human0.86942802
122ERG_21242973_ChIP-ChIP_JURKAT_Human0.86885683
123NCOR1_26117541_ChIP-Seq_K562_Human0.86819308
124ELK4_26923725_Chip-Seq_MESODERM_Mouse0.86512318
125GATA2_19941826_ChIP-Seq_K562_Human0.86293291
126OCT4_19829295_ChIP-Seq_ESCs_Human0.84217669
127ZNF274_21170338_ChIP-Seq_K562_Hela0.83435311
128MYC_27129775_Chip-Seq_CORNEA_Mouse0.83160141
129UTX_26944678_Chip-Seq_JUKART_Human0.82714116
130FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.82563372
131FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.82496232
132KLF4_19829295_ChIP-Seq_ESCs_Human0.82491191
133CTCF_21964334_ChIP-Seq_BJAB-B_Human0.81790276

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000751_myopathy3.39929378
2MP0005410_abnormal_fertilization2.84863648
3MP0008961_abnormal_basal_metabolism2.81668612
4MP0008057_abnormal_DNA_replication2.79642927
5MP0004130_abnormal_muscle_cell2.73354709
6MP0003646_muscle_fatigue2.70698910
7MP0003705_abnormal_hypodermis_morpholog2.66993577
8MP0004084_abnormal_cardiac_muscle2.66770960
9MP0002009_preneoplasia2.63003722
10MP0005360_urolithiasis2.58221233
11MP0003878_abnormal_ear_physiology2.42856653
12MP0005377_hearing/vestibular/ear_phenot2.42856653
13MP0002139_abnormal_hepatobiliary_system2.42313548
14MP0003045_fibrosis2.30548553
15MP0003252_abnormal_bile_duct2.28032924
16MP0005670_abnormal_white_adipose2.14166375
17MP0005409_darkened_coat_color2.08866569
18MP0008877_abnormal_DNA_methylation2.03100171
19MP0005365_abnormal_bile_salt1.99980631
20MP0005666_abnormal_adipose_tissue1.93900510
21MP0005451_abnormal_body_composition1.90084210
22MP0004510_myositis1.89614989
23MP0010329_abnormal_lipoprotein_level1.88792956
24MP0004036_abnormal_muscle_relaxation1.88780408
25MP0002837_dystrophic_cardiac_calcinosis1.88062937
26MP0004087_abnormal_muscle_fiber1.86725373
27MP0005464_abnormal_platelet_physiology1.86534516
28MP0008995_early_reproductive_senescence1.86474246
29MP0000569_abnormal_digit_pigmentation1.85943207
30MP0005083_abnormal_biliary_tract1.72769382
31MP0000566_synostosis1.69556597
32MP0004043_abnormal_pH_regulation1.62494626
33MP0004808_abnormal_hematopoietic_stem1.59841512
34MP0008260_abnormal_autophagy1.54689272
35MP0005076_abnormal_cell_differentiation1.54362598
36MP0002249_abnormal_larynx_morphology1.51272765
37MP0000537_abnormal_urethra_morphology1.51021402
38MP0002108_abnormal_muscle_morphology1.49031144
39MP0002127_abnormal_cardiovascular_syste1.48807860
40MP0004859_abnormal_synaptic_plasticity1.47238235
41MP0010630_abnormal_cardiac_muscle1.45954815
42MP0002971_abnormal_brown_adipose1.45892055
43MP0005623_abnormal_meninges_morphology1.43954296
44MP0005085_abnormal_gallbladder_physiolo1.41792222
45MP0004233_abnormal_muscle_weight1.41619691
46MP0009278_abnormal_bone_marrow1.40568418
47MP0005375_adipose_tissue_phenotype1.39330715
48MP0009780_abnormal_chondrocyte_physiolo1.34869730
49MP0002970_abnormal_white_adipose1.33159807
50MP0002822_catalepsy1.32653267
51MP0005330_cardiomyopathy1.31190705
52MP0002168_other_aberrant_phenotype1.30352643
53MP0003698_abnormal_male_reproductive1.28669607
54MP0000428_abnormal_craniofacial_morphol1.28175278
55MP0006138_congestive_heart_failure1.27560864
56MP0003300_gastrointestinal_ulcer1.26569073
57MP0005647_abnormal_sex_gland1.26233243
58MP0002909_abnormal_adrenal_gland1.24114983
59MP0003984_embryonic_growth_retardation1.20021191
60MP0003656_abnormal_erythrocyte_physiolo1.19783418
61MP0000747_muscle_weakness1.19711969
62MP0004215_abnormal_myocardial_fiber1.19628254
63MP0000609_abnormal_liver_physiology1.19603043
64MP0005058_abnormal_lysosome_morphology1.19446411
65MP0001348_abnormal_lacrimal_gland1.18647636
66MP0004185_abnormal_adipocyte_glucose1.17679442
67MP0003763_abnormal_thymus_physiology1.17283450
68MP0002269_muscular_atrophy1.17263529
69MP0002396_abnormal_hematopoietic_system1.15974252
70MP0002106_abnormal_muscle_physiology1.15681807
71MP0002925_abnormal_cardiovascular_devel1.14851262
72MP0002128_abnormal_blood_circulation1.14789209
73MP0001849_ear_inflammation1.14630354
74MP0002088_abnormal_embryonic_growth/wei1.12476372
75MP0001873_stomach_inflammation1.12159763
76MP0003115_abnormal_respiratory_system1.10716287
77MP0001929_abnormal_gametogenesis1.10583940
78MP0005187_abnormal_penis_morphology1.10118525
79MP0004272_abnormal_basement_membrane1.08071293
80MP0004145_abnormal_muscle_electrophysio1.07934145
81MP0005620_abnormal_muscle_contractility1.05849226
82MP0002653_abnormal_ependyma_morphology1.05098115
83MP0005167_abnormal_blood-brain_barrier1.04649995
84MP0001270_distended_abdomen1.02981707
85MP0001299_abnormal_eye_distance/1.02350367
86MP0002118_abnormal_lipid_homeostasis1.01900661
87MP0002254_reproductive_system_inflammat1.01673541
88MP0003091_abnormal_cell_migration1.00910081
89MP0003950_abnormal_plasma_membrane1.00779730
90MP0003566_abnormal_cell_adhesion1.00370800
91MP0000003_abnormal_adipose_tissue0.99068672
92MP0008775_abnormal_heart_ventricle0.98823021
93MP0001544_abnormal_cardiovascular_syste0.98788824
94MP0005385_cardiovascular_system_phenoty0.98788824
95MP0005332_abnormal_amino_acid0.97665636
96MP0004197_abnormal_fetal_growth/weight/0.97423177
97MP0004264_abnormal_extraembryonic_tissu0.95607634
98MP0009672_abnormal_birth_weight0.95474064
99MP0000759_abnormal_skeletal_muscle0.95239334
100MP0005319_abnormal_enzyme/_coenzyme0.94546066
101MP0005380_embryogenesis_phenotype0.94189598
102MP0001672_abnormal_embryogenesis/_devel0.94189598
103MP0005503_abnormal_tendon_morphology0.93377861
104MP0002116_abnormal_craniofacial_bone0.92487490
105MP0000733_abnormal_muscle_development0.92340172
106MP0001175_abnormal_lung_morphology0.92192768
107MP0004858_abnormal_nervous_system0.92183218
108MP0003329_amyloid_beta_deposits0.91997541
109MP0008875_abnormal_xenobiotic_pharmacok0.91651567
110MP0010368_abnormal_lymphatic_system0.91642298
111MP0003191_abnormal_cellular_cholesterol0.91319978
112MP0002084_abnormal_developmental_patter0.90836467
113MP0002086_abnormal_extraembryonic_tissu0.90111009
114MP0000767_abnormal_smooth_muscle0.90076529
115MP0009703_decreased_birth_body0.89884556
116MP0003942_abnormal_urinary_system0.89617277
117MP0003279_aneurysm0.89107525
118MP0000703_abnormal_thymus_morphology0.87525592
119MP0003935_abnormal_craniofacial_develop0.86709641
120MP0001614_abnormal_blood_vessel0.86268594
121MP0003943_abnormal_hepatobiliary_system0.85863489
122MP0001502_abnormal_circadian_rhythm0.85820292
123MP0009046_muscle_twitch0.85741757
124MP0002132_abnormal_respiratory_system0.85401899
125MP0003948_abnormal_gas_homeostasis0.84384388
126MP0000432_abnormal_head_morphology0.83235515
127MP0005584_abnormal_enzyme/coenzyme_acti0.82974440
128MP0009840_abnormal_foam_cell0.82674482
129MP0000013_abnormal_adipose_tissue0.82117084
130MP0003879_abnormal_hair_cell0.82066893
131MP0009384_cardiac_valve_regurgitation0.81928042
132MP0000534_abnormal_ureter_morphology0.81734784
133MP0000749_muscle_degeneration0.81545554
134MP0005369_muscle_phenotype0.80404623
135MP0000383_abnormal_hair_follicle0.79935747
136MP0002234_abnormal_pharynx_morphology0.79492695
137MP0000750_abnormal_muscle_regeneration0.79391321
138MP0010352_gastrointestinal_tract_polyps0.79256686
139MP0002166_altered_tumor_susceptibility0.79121559
140MP0002972_abnormal_cardiac_muscle0.78697579
141MP0001915_intracranial_hemorrhage0.78549718
142MP0003111_abnormal_nucleus_morphology0.77728654
143MP0005535_abnormal_body_temperature0.77246937
144MP0002210_abnormal_sex_determination0.77239145
145MP0002233_abnormal_nose_morphology0.76802256
146MP0003137_abnormal_impulse_conducting0.76535204
147MP0005334_abnormal_fat_pad0.76317884
148MP0000604_amyloidosis0.76229404
149MP0001661_extended_life_span0.74500575
150MP0002928_abnormal_bile_duct0.73422375
151MP0001958_emphysema0.72895133
152MP0009115_abnormal_fat_cell0.71913611
153MP0001784_abnormal_fluid_regulation0.71814802
154MP0001756_abnormal_urination0.71654377
155MP0000266_abnormal_heart_morphology0.71586705
156MP0005310_abnormal_salivary_gland0.70722144
157MP0002078_abnormal_glucose_homeostasis0.70436266
158MP0001145_abnormal_male_reproductive0.70197374

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the lower motor neuron (HP:0002366)4.14787812
2Exercise-induced myalgia (HP:0003738)3.62893847
3Nasal polyposis (HP:0100582)3.47315298
4Abnormality of the aortic arch (HP:0012303)3.27955124
5Broad palm (HP:0001169)3.26974108
6Muscle fiber inclusion bodies (HP:0100299)3.26222955
7Cerebral aneurysm (HP:0004944)3.17725193
8Hyperacusis (HP:0010780)3.17263692
9Hand muscle atrophy (HP:0009130)3.12833524
10Dysmetric saccades (HP:0000641)3.12160412
11Absent/shortened dynein arms (HP:0200106)3.11780418
12Dynein arm defect of respiratory motile cilia (HP:0012255)3.11780418
13Abnormality of the nasal mucosa (HP:0000433)3.11394226
14Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.07941765
15Nemaline bodies (HP:0003798)3.05267561
16Distal upper limb amyotrophy (HP:0007149)3.01617899
17Upper limb amyotrophy (HP:0009129)3.01617899
18Male infertility (HP:0003251)2.94961316
19Hyporeflexia of lower limbs (HP:0002600)2.94663677
20Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.94415344
21Prolonged bleeding time (HP:0003010)2.91124835
22Difficulty running (HP:0009046)2.86396654
23Bundle branch block (HP:0011710)2.82226531
24Obstructive sleep apnea (HP:0002870)2.78910664
25Abnormality of the calcaneus (HP:0008364)2.76387511
26Myoglobinuria (HP:0002913)2.73060736
27Renovascular hypertension (HP:0100817)2.70077061
28Myopathic facies (HP:0002058)2.68624188
29Atrioventricular block (HP:0001678)2.67661850
30Hypoplastic iliac wings (HP:0002866)2.64370358
31Elfin facies (HP:0004428)2.60819055
32Centrally nucleated skeletal muscle fibers (HP:0003687)2.56263805
33Long eyelashes (HP:0000527)2.49488593
34Narrow palate (HP:0000189)2.39629343
35Lymphangioma (HP:0100764)2.38411467
36Dislocated radial head (HP:0003083)2.38118953
37Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.37564145
38Sudden death (HP:0001699)2.35855845
39Infertility (HP:0000789)2.30969135
40Ulnar deviation of the wrist (HP:0003049)2.30787982
41Exercise-induced muscle cramps (HP:0003710)2.30221984
42Asymmetric septal hypertrophy (HP:0001670)2.29730201
43Menorrhagia (HP:0000132)2.28536717
44Hypoplastic ischia (HP:0003175)2.28162069
45Gonadotropin excess (HP:0000837)2.25720143
46Abnormality of the fingertips (HP:0001211)2.22693015
47Abnormality of the radial head (HP:0003995)2.22605619
48Deep venous thrombosis (HP:0002625)2.22595661
49Facial diplegia (HP:0001349)2.21756630
50Mitral stenosis (HP:0001718)2.18441610
51Heart block (HP:0012722)2.18372748
52Increased connective tissue (HP:0009025)2.17962896
53Broad metatarsal (HP:0001783)2.17581888
54Macroorchidism (HP:0000053)2.16129165
55Heterotopia (HP:0002282)2.16097437
56Rimmed vacuoles (HP:0003805)2.15774796
57High anterior hairline (HP:0009890)2.14725416
58Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.11902062
59Short 4th metacarpal (HP:0010044)2.11902062
60Pigmentary retinal degeneration (HP:0001146)2.08711712
61Protruding tongue (HP:0010808)2.08631023
62Abnormality of the ischium (HP:0003174)2.07987214
63Increased variability in muscle fiber diameter (HP:0003557)2.07669732
64Mesangial abnormality (HP:0001966)2.04099628
65Shallow orbits (HP:0000586)2.03396580
66Mildly elevated creatine phosphokinase (HP:0008180)2.03245682
67Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.03041072
68Neoplasm of the heart (HP:0100544)2.02872991
69Impulsivity (HP:0100710)2.01273037
70Increased mean platelet volume (HP:0011877)2.00780476
71Complete atrioventricular canal defect (HP:0001674)1.95677313
72Difficulty climbing stairs (HP:0003551)1.95648222
73Bowel incontinence (HP:0002607)1.95473469
74Calcaneovalgus deformity (HP:0001848)1.95462493
75Abnormal atrioventricular conduction (HP:0005150)1.95364480
76Broad thumb (HP:0011304)1.95196240
77Muscle fiber splitting (HP:0003555)1.94689098
78Abnormality of the 4th metacarpal (HP:0010012)1.94507151
79Rectal prolapse (HP:0002035)1.93125492
80Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.92618064
81Trigonocephaly (HP:0000243)1.90670729
82Subacute progressive viral hepatitis (HP:0006572)1.90626478
83Round ear (HP:0100830)1.88970282
84Long toe (HP:0010511)1.87964426
85Aneurysm (HP:0002617)1.87866900
86Enlarged penis (HP:0000040)1.87766584
87Hypoalphalipoproteinemia (HP:0003233)1.87272687
88Vertebral arch anomaly (HP:0008438)1.85584553
89Sparse lateral eyebrow (HP:0005338)1.85468740
90Flat acetabular roof (HP:0003180)1.85016548
91Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.84912302
92Atelectasis (HP:0100750)1.84815731
93Abnormal platelet volume (HP:0011876)1.84618474
94Hyperthyroidism (HP:0000836)1.84418190
95Hydroxyprolinuria (HP:0003080)1.84371353
96Abnormality of proline metabolism (HP:0010907)1.84371353
97Testicular neoplasm (HP:0010788)1.84214250
98Metaphyseal cupping (HP:0003021)1.83755972
99Insomnia (HP:0100785)1.83434108
100Abnormal large intestine physiology (HP:0012700)1.83360932
101Abnormality of the left ventricular outflow tract (HP:0011103)1.83280304
102Subaortic stenosis (HP:0001682)1.83280304
103Abnormality of the epiphyses of the hand (HP:0005924)1.82943736
104Type 1 muscle fiber predominance (HP:0003803)1.82192640
105Patellar dislocation (HP:0002999)1.81549445
106Broad phalanges of the hand (HP:0009768)1.81282079
107Hypoplastic ilia (HP:0000946)1.81183280
108Abnormality of the intervertebral disk (HP:0005108)1.80629138
109Increased density of long bones (HP:0006392)1.80267574
110Truncus arteriosus (HP:0001660)1.80003185
111Abnormality of glutamine family amino acid metabolism (HP:0010902)1.79953355
112Mitral regurgitation (HP:0001653)1.79548719
113Ectopic kidney (HP:0000086)1.79015222
114EMG: neuropathic changes (HP:0003445)1.78556697
115Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.78141101
116Short 1st metacarpal (HP:0010034)1.78141101
117Ketosis (HP:0001946)1.77551192
118Prolonged QT interval (HP:0001657)1.77222327
119Hepatoblastoma (HP:0002884)1.76745725
120Ventricular fibrillation (HP:0001663)1.75925394
121Gout (HP:0001997)1.74694659
122Azoospermia (HP:0000027)1.74344340
123Thick eyebrow (HP:0000574)1.73867410
124Abnormality of skeletal muscle fiber size (HP:0012084)1.73567189
125Obsessive-compulsive behavior (HP:0000722)1.73076344
126Broad finger (HP:0001500)1.72836906
127Abnormal hair whorl (HP:0010721)1.72605918
128Short 5th finger (HP:0009237)1.72443520
129Postural instability (HP:0002172)1.71168868
130Abnormality of the distal phalanx of the thumb (HP:0009617)1.70606442
131Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.70190107
132Arthropathy (HP:0003040)1.68908621
133Disproportionate tall stature (HP:0001519)1.68216311
134Poikilocytosis (HP:0004447)1.66431419
135Stroke (HP:0001297)1.66065007
136Sandal gap (HP:0001852)1.65797632
137Syncope (HP:0001279)1.65678503
138Abnormality of the humeroradial joint (HP:0100744)1.64568971
139Atrial fibrillation (HP:0005110)1.64114268
140Hypercholesterolemia (HP:0003124)1.63913542
141Abnormality of the wing of the ilium (HP:0011867)1.63623235
142Hyperkalemia (HP:0002153)1.63482646
143Mask-like facies (HP:0000298)1.63458102
144Ventricular arrhythmia (HP:0004308)1.62605401
145Aortic aneurysm (HP:0004942)1.62190025
146Mitral valve prolapse (HP:0001634)1.61483779
147Broad ribs (HP:0000885)1.61375707
148Germ cell neoplasia (HP:0100728)1.61049769
149Shawl scrotum (HP:0000049)1.60929529
150Polycythemia (HP:0001901)1.60570651
151Deformed tarsal bones (HP:0008119)1.60198694
152Hemiplegia (HP:0002301)1.59674803
153Deep palmar crease (HP:0006191)1.59327762
154Bell-shaped thorax (HP:0001591)1.59083123
155Abnormality of the phalanges of the hallux (HP:0010057)1.58943445
156Bladder diverticulum (HP:0000015)1.58352636
157Turricephaly (HP:0000262)1.58071741
158Xanthomatosis (HP:0000991)1.58003761
159Truncal obesity (HP:0001956)1.57649910
160Reticulocytosis (HP:0001923)1.57478931
161Upper motor neuron abnormality (HP:0002127)1.57397882
162Thin bony cortex (HP:0002753)1.57359646
163Self-mutilation (HP:0000742)1.57259681
164Fibular hypoplasia (HP:0003038)1.57219852
165Striae distensae (HP:0001065)1.57205405
166Back pain (HP:0003418)1.57001804
167Precocious puberty (HP:0000826)1.56972316
168Resting tremor (HP:0002322)1.56214012
169Thin ribs (HP:0000883)1.55653188
170Broad phalanx (HP:0006009)1.55239126
171Long palpebral fissure (HP:0000637)1.55162742
172Frequent falls (HP:0002359)1.54451398
173Generalized muscle weakness (HP:0003324)1.53056663
174Overlapping toe (HP:0001845)1.52510360

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.62460911
2PDK43.41535025
3PDK33.41535025
4PKN22.87103040
5PRKD32.81794916
6RIPK12.80027234
7AKT32.34571931
8CAMK1G2.34013520
9OBSCN2.29241379
10ICK2.26816190
11TTN2.23456997
12SIK12.15552762
13MAP3K101.96139641
14PTK61.88293552
15SIK21.81482951
16CDK121.80380609
17EEF2K1.77226593
18PDK21.75234940
19ERN11.73493904
20LATS11.62002405
21LMTK21.58086237
22PNCK1.51016063
23STK381.49792406
24TYRO31.46828804
25MAPK111.44337360
26PDGFRA1.44076339
27FGFR41.42802010
28MAP3K41.42453476
29STK391.39039591
30PRPF4B1.38666926
31CAMK1D1.33978381
32IRAK31.29647278
33MAP3K71.28053891
34TRPM71.25378157
35SGK31.18732251
36PHKG21.08648179
37PHKG11.08648179
38MELK1.08058249
39MTOR1.07235445
40EPHA31.05253417
41PRKCH1.04913733
42JAK11.00608455
43WNK40.97805527
44NEK20.97202725
45PTK2B0.96378995
46MAP2K40.96144440
47TNK20.93376780
48BMX0.91748492
49CDK80.91720914
50BRD40.89910856
51DMPK0.89551756
52TYK20.88907371
53PAK60.88576060
54RET0.88561569
55HIPK20.87265626
56PIK3CG0.86937323
57NEK10.85896680
58PINK10.85519517
59MAP3K60.84718357
60CAMK10.84050365
61NTRK20.82387196
62TAOK10.80579126
63SGK20.77019266
64WNK10.76201496
65ALK0.73295448
66PRKAA10.72990500
67CAMKK10.72501125
68DDR20.71930374
69FGFR30.71652605
70INSRR0.71341865
71STK30.70844637
72MAP3K20.69720308
73BTK0.69037396
74PDGFRB0.67916451
75IRAK10.67456941
76MAP3K130.67396099
77PRKAA20.66851952
78DAPK20.66298280
79MAP4K10.65498144
80RPS6KA20.64347351
81RPS6KL10.64279307
82RPS6KC10.64279307
83MUSK0.64053710
84DYRK1B0.63678169
85EPHB10.63494227
86MARK30.63015602
87PDK10.62879479
88NLK0.62806563
89MARK20.62747174
90JAK20.59804598
91PAK40.59493162
92PAK30.58903635
93KSR20.57485490
94RPS6KA60.57144161
95NEK90.57114844
96KSR10.57057845
97FGFR10.56669027
98CHEK10.55800928
99CDC42BPA0.54210109
100MAPK100.54056542
101CDK90.52604710
102MARK10.52589344
103HCK0.52210584
104CAMK40.51654734
105CHUK0.51274921
106MYLK0.50235174
107PTK20.49822364
108PDPK10.49054276
109MAPKAPK30.48998099
110ROCK10.45540021
111SMG10.45439837
112PAK20.45232177
113AKT10.44166790
114SGK4940.42962448
115SGK2230.42962448
116PRKD20.42771020
117LATS20.42373221
118MAPK10.42370551
119PRKCZ0.42069629
120ZAP700.41712579
121CDK20.41318502
122MAP2K30.41164315
123JAK30.41162621
124RPS6KA30.40785033
125CDK70.39988834
126STK38L0.39531884
127SCYL20.39085393
128TBK10.38852088
129SGK10.38842802
130GSK3B0.38823201
131MAPK130.38070451
132MAPK120.37908316
133MAPK80.35805887
134AKT20.35201941
135PRKACG0.34382446
136PRKD10.34337205
137CDK40.33539235

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.02931403
2Nitrogen metabolism_Homo sapiens_hsa009102.35694190
3Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.16722719
4Fatty acid biosynthesis_Homo sapiens_hsa000612.09997244
5Fatty acid degradation_Homo sapiens_hsa000712.09486584
6Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.07056849
72-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.04947561
8Lysine degradation_Homo sapiens_hsa003101.82473184
9Fatty acid metabolism_Homo sapiens_hsa012121.81615201
10PPAR signaling pathway_Homo sapiens_hsa033201.78698419
11Propanoate metabolism_Homo sapiens_hsa006401.71167650
12Arginine biosynthesis_Homo sapiens_hsa002201.69547460
13Adipocytokine signaling pathway_Homo sapiens_hsa049201.59362861
14Pancreatic cancer_Homo sapiens_hsa052121.57344775
15Insulin resistance_Homo sapiens_hsa049311.51691573
16Renal cell carcinoma_Homo sapiens_hsa052111.51210104
17Bile secretion_Homo sapiens_hsa049761.48329722
18Glucagon signaling pathway_Homo sapiens_hsa049221.47203510
19Choline metabolism in cancer_Homo sapiens_hsa052311.46464163
20Dorso-ventral axis formation_Homo sapiens_hsa043201.44549613
21Platelet activation_Homo sapiens_hsa046111.44174961
22Pyruvate metabolism_Homo sapiens_hsa006201.40412388
23Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.38260556
24Other glycan degradation_Homo sapiens_hsa005111.35933830
25FoxO signaling pathway_Homo sapiens_hsa040681.32849403
26Type II diabetes mellitus_Homo sapiens_hsa049301.28392335
27Circadian rhythm_Homo sapiens_hsa047101.27008016
28Adherens junction_Homo sapiens_hsa045201.20498014
29ErbB signaling pathway_Homo sapiens_hsa040121.19381212
30Insulin signaling pathway_Homo sapiens_hsa049101.18470852
31Primary bile acid biosynthesis_Homo sapiens_hsa001201.18435034
32Dilated cardiomyopathy_Homo sapiens_hsa054141.15647693
33Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.14592645
34Prostate cancer_Homo sapiens_hsa052151.13856282
35Tryptophan metabolism_Homo sapiens_hsa003801.13629219
36Carbon metabolism_Homo sapiens_hsa012001.11787660
37Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.08547044
38Colorectal cancer_Homo sapiens_hsa052101.06123934
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.05772611
40MicroRNAs in cancer_Homo sapiens_hsa052061.05235946
41Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.05081727
42Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.04987586
43Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03382054
44Thyroid hormone signaling pathway_Homo sapiens_hsa049191.01759661
45Butanoate metabolism_Homo sapiens_hsa006501.01623943
46AMPK signaling pathway_Homo sapiens_hsa041521.00940999
47Glycerolipid metabolism_Homo sapiens_hsa005610.99651889
48Carbohydrate digestion and absorption_Homo sapiens_hsa049730.99338281
49mTOR signaling pathway_Homo sapiens_hsa041500.98629494
50Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.98434309
51Vascular smooth muscle contraction_Homo sapiens_hsa042700.97697169
52Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.96446982
53Central carbon metabolism in cancer_Homo sapiens_hsa052300.94941530
54ABC transporters_Homo sapiens_hsa020100.94382772
55Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.93315878
56Longevity regulating pathway - mammal_Homo sapiens_hsa042110.93183225
57Glycerophospholipid metabolism_Homo sapiens_hsa005640.92364616
58Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.91045812
59Viral myocarditis_Homo sapiens_hsa054160.90919913
60Long-term depression_Homo sapiens_hsa047300.90844889
61Aldosterone synthesis and secretion_Homo sapiens_hsa049250.89211995
62Biosynthesis of amino acids_Homo sapiens_hsa012300.88848085
63Hepatitis B_Homo sapiens_hsa051610.87317509
64cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83705864
65Renin secretion_Homo sapiens_hsa049240.83320515
66Jak-STAT signaling pathway_Homo sapiens_hsa046300.83168961
67Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.82862100
68Starch and sucrose metabolism_Homo sapiens_hsa005000.81817559
69T cell receptor signaling pathway_Homo sapiens_hsa046600.80278489
70Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.80173377
71Gastric acid secretion_Homo sapiens_hsa049710.79947760
72Small cell lung cancer_Homo sapiens_hsa052220.74867001
73Focal adhesion_Homo sapiens_hsa045100.73178723
74Olfactory transduction_Homo sapiens_hsa047400.71485396
75Toxoplasmosis_Homo sapiens_hsa051450.70871593
76Bladder cancer_Homo sapiens_hsa052190.70301710
77MAPK signaling pathway_Homo sapiens_hsa040100.69756497
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.69038475
79Estrogen signaling pathway_Homo sapiens_hsa049150.68884500
80Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.68586571
81Complement and coagulation cascades_Homo sapiens_hsa046100.67612045
82Hepatitis C_Homo sapiens_hsa051600.67169796
83Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.67031619
84Thyroid cancer_Homo sapiens_hsa052160.66083330
85Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.65683328
86Amoebiasis_Homo sapiens_hsa051460.65512057
87Chronic myeloid leukemia_Homo sapiens_hsa052200.65052480
88cAMP signaling pathway_Homo sapiens_hsa040240.64991214
89Hippo signaling pathway_Homo sapiens_hsa043900.64218004
90Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.61470812
91ECM-receptor interaction_Homo sapiens_hsa045120.60958473
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.60060581
93Thyroid hormone synthesis_Homo sapiens_hsa049180.59212131
94Neurotrophin signaling pathway_Homo sapiens_hsa047220.59177843
95Gap junction_Homo sapiens_hsa045400.58726763
96Endometrial cancer_Homo sapiens_hsa052130.58023643
97Pathways in cancer_Homo sapiens_hsa052000.57625729
98Oxytocin signaling pathway_Homo sapiens_hsa049210.57291001
99Phototransduction_Homo sapiens_hsa047440.57087256
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.56834686
101beta-Alanine metabolism_Homo sapiens_hsa004100.56304628
102Selenocompound metabolism_Homo sapiens_hsa004500.55837400
103mRNA surveillance pathway_Homo sapiens_hsa030150.55528760
104Endocytosis_Homo sapiens_hsa041440.55301981
105TNF signaling pathway_Homo sapiens_hsa046680.54884316
106Salivary secretion_Homo sapiens_hsa049700.54645849
107Calcium signaling pathway_Homo sapiens_hsa040200.54351319
108Ovarian steroidogenesis_Homo sapiens_hsa049130.54174748
109Circadian entrainment_Homo sapiens_hsa047130.53983151
110Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.53303593
111VEGF signaling pathway_Homo sapiens_hsa043700.52252271
112TGF-beta signaling pathway_Homo sapiens_hsa043500.51881799
113Prolactin signaling pathway_Homo sapiens_hsa049170.49984612
114Insulin secretion_Homo sapiens_hsa049110.49193612
115Glioma_Homo sapiens_hsa052140.49124691
116PI3K-Akt signaling pathway_Homo sapiens_hsa041510.48863798
117Long-term potentiation_Homo sapiens_hsa047200.47712855
118Non-small cell lung cancer_Homo sapiens_hsa052230.47592699
119Acute myeloid leukemia_Homo sapiens_hsa052210.47208577
120Chemokine signaling pathway_Homo sapiens_hsa040620.46674790
121Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46488768
122Cysteine and methionine metabolism_Homo sapiens_hsa002700.45934727
123Melanogenesis_Homo sapiens_hsa049160.45922511
124Proteoglycans in cancer_Homo sapiens_hsa052050.45824228
125AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.45748150
126Viral carcinogenesis_Homo sapiens_hsa052030.45742326
127Fat digestion and absorption_Homo sapiens_hsa049750.45670848
128RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45142594
129Protein digestion and absorption_Homo sapiens_hsa049740.44896911
130HTLV-I infection_Homo sapiens_hsa051660.44449229
131Pentose phosphate pathway_Homo sapiens_hsa000300.44369620
132Regulation of autophagy_Homo sapiens_hsa041400.44198713
133Inositol phosphate metabolism_Homo sapiens_hsa005620.44028545
134Caffeine metabolism_Homo sapiens_hsa002320.43738224
135Vitamin digestion and absorption_Homo sapiens_hsa049770.43701635
136Notch signaling pathway_Homo sapiens_hsa043300.43536230
137Pentose and glucuronate interconversions_Homo sapiens_hsa000400.42491115
138Osteoclast differentiation_Homo sapiens_hsa043800.42450369
139Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.42050279
140Regulation of actin cytoskeleton_Homo sapiens_hsa048100.41789641
141HIF-1 signaling pathway_Homo sapiens_hsa040660.41670244
142Phospholipase D signaling pathway_Homo sapiens_hsa040720.40512891
143GnRH signaling pathway_Homo sapiens_hsa049120.40193098
144Morphine addiction_Homo sapiens_hsa050320.39458984
145B cell receptor signaling pathway_Homo sapiens_hsa046620.38768117
146Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38071352
147Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.37053281

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »