KAT8

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit biogenesis (GO:0042274)6.88891504
2negative regulation of erythrocyte differentiation (GO:0045647)5.85004906
3positive regulation of gamma-delta T cell activation (GO:0046645)5.70379873
4maturation of SSU-rRNA (GO:0030490)5.37955038
5viral transcription (GO:0019083)5.37683026
6rRNA modification (GO:0000154)5.33229307
7mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.21975227
8ATP synthesis coupled proton transport (GO:0015986)5.20486966
9energy coupled proton transport, down electrochemical gradient (GO:0015985)5.20486966
10translational termination (GO:0006415)5.13652620
11negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.91028292
12negative regulation of cell killing (GO:0031342)4.91028292
13establishment of integrated proviral latency (GO:0075713)4.79349175
14rRNA methylation (GO:0031167)4.78444970
15proteasome assembly (GO:0043248)4.72924351
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.71755772
17nucleoside diphosphate catabolic process (GO:0009134)4.63641854
18transcription elongation from RNA polymerase III promoter (GO:0006385)4.51554073
19termination of RNA polymerase III transcription (GO:0006386)4.51554073
20antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.47577116
21cotranslational protein targeting to membrane (GO:0006613)4.44648255
22mannose metabolic process (GO:0006013)4.43951939
23modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.43393003
24positive regulation by organism of defense response of other organism involved in symbiotic interact4.43393003
25modulation by symbiont of host immune response (GO:0052553)4.43393003
26positive regulation by symbiont of host defense response (GO:0052509)4.43393003
27modulation by symbiont of host defense response (GO:0052031)4.43393003
28modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.43393003
29SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.39228170
30protein targeting to ER (GO:0045047)4.35620720
31preassembly of GPI anchor in ER membrane (GO:0016254)4.34205774
32response to peptidoglycan (GO:0032494)4.29519696
33regulation of gamma-delta T cell activation (GO:0046643)4.24930093
34establishment of protein localization to endoplasmic reticulum (GO:0072599)4.15843351
35translational elongation (GO:0006414)4.12477703
36cellular protein complex disassembly (GO:0043624)4.12313494
37protein localization to endoplasmic reticulum (GO:0070972)4.11134533
38termination of RNA polymerase I transcription (GO:0006363)4.11107201
39transcription elongation from RNA polymerase I promoter (GO:0006362)4.11059969
40central nervous system myelination (GO:0022010)4.07198042
41axon ensheathment in central nervous system (GO:0032291)4.07198042
42RNA capping (GO:0036260)4.04557363
437-methylguanosine RNA capping (GO:0009452)4.04557363
44ribosomal large subunit biogenesis (GO:0042273)4.04185077
45establishment of protein localization to mitochondrial membrane (GO:0090151)4.04083125
46chaperone-mediated protein transport (GO:0072321)4.02951488
47regulation of gamma-delta T cell differentiation (GO:0045586)4.00475288
48viral life cycle (GO:0019058)4.00067746
49spliceosomal snRNP assembly (GO:0000387)3.99739801
507-methylguanosine mRNA capping (GO:0006370)3.98968414
51response to muramyl dipeptide (GO:0032495)3.97777879
52establishment of viral latency (GO:0019043)3.92836823
53spliceosomal complex assembly (GO:0000245)3.92680988
54protein-cofactor linkage (GO:0018065)3.92225947
55GTP biosynthetic process (GO:0006183)3.88536899
56regulation of T-helper 2 cell differentiation (GO:0045628)3.88314062
57positive thymic T cell selection (GO:0045059)3.87086217
58translational initiation (GO:0006413)3.85258218
59detection of other organism (GO:0098543)3.80026078
60ribonucleoprotein complex biogenesis (GO:0022613)3.76548266
61ribosomal small subunit assembly (GO:0000028)3.73990730
62nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.73468118
63transcription from RNA polymerase I promoter (GO:0006360)3.72969274
64positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.70764562
65exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.70512695
66negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.69788516
67nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.69459431
68regulation of B cell receptor signaling pathway (GO:0050855)3.68553697
69respiratory electron transport chain (GO:0022904)3.68252839
70detection of bacterium (GO:0016045)3.67998699
71macrophage activation involved in immune response (GO:0002281)3.67911199
72protein neddylation (GO:0045116)3.66156517
73translation (GO:0006412)3.65294580
74antigen processing and presentation of endogenous antigen (GO:0019883)3.64888179
75neutrophil activation involved in immune response (GO:0002283)3.63210210
76electron transport chain (GO:0022900)3.59224215
77antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.56697144
78germinal center formation (GO:0002467)3.56126085
79rRNA processing (GO:0006364)3.51046623
80negative regulation of lymphocyte mediated immunity (GO:0002707)3.49740379
81negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.49617187
82protein complex disassembly (GO:0043241)3.47627099
83GPI anchor biosynthetic process (GO:0006506)3.45155792
84positive regulation of B cell differentiation (GO:0045579)3.44434835
85DNA damage response, detection of DNA damage (GO:0042769)3.39311958
86regulation of mast cell degranulation (GO:0043304)3.38455914
87transcription initiation from RNA polymerase I promoter (GO:0006361)3.38300793
88tongue development (GO:0043586)3.38290709
89rRNA metabolic process (GO:0016072)3.36513248
90UTP biosynthetic process (GO:0006228)3.36461170
91detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580)3.35977459
92positive regulation of protein homodimerization activity (GO:0090073)3.34845293
93negative regulation of T cell mediated immunity (GO:0002710)3.33920966
94regulation of ARF GTPase activity (GO:0032312)3.31940645
95regulation of myeloid leukocyte mediated immunity (GO:0002886)3.26744973
96macromolecular complex disassembly (GO:0032984)3.26601518
97cellular extravasation (GO:0045123)3.25929021
98detection of external biotic stimulus (GO:0098581)3.25831188
99cellular component biogenesis (GO:0044085)3.25735356
100B cell receptor signaling pathway (GO:0050853)3.21780107
101CENP-A containing nucleosome assembly (GO:0034080)3.21660892
102leukocyte aggregation (GO:0070486)3.18697056
1033-UTR-mediated mRNA stabilization (GO:0070935)3.17177524
104mucosal-associated lymphoid tissue development (GO:0048537)3.17157568
105Peyers patch development (GO:0048541)3.17157568
106regulation of leukocyte degranulation (GO:0043300)3.17114887
107detection of molecule of bacterial origin (GO:0032490)3.16575548
108negative regulation of type 2 immune response (GO:0002829)3.15504420
109negative regulation of leukocyte mediated immunity (GO:0002704)3.14898605
110positive T cell selection (GO:0043368)3.13862064
111transcription-coupled nucleotide-excision repair (GO:0006283)3.13543706
112antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.13260305
113negative regulation of interleukin-12 production (GO:0032695)3.12568639
114positive regulation of type 2 immune response (GO:0002830)3.11368548
115DNA deamination (GO:0045006)3.09277122
116thymic T cell selection (GO:0045061)3.09175287
117chromatin remodeling at centromere (GO:0031055)3.09069182
118GPI anchor metabolic process (GO:0006505)3.08673900
119histone H4 deacetylation (GO:0070933)3.06477230
120protein targeting to mitochondrion (GO:0006626)3.03450189
121negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.02279189
122positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.02140868
123establishment of protein localization to mitochondrion (GO:0072655)3.01295440
124peptidyl-histidine modification (GO:0018202)3.01115947
125C-terminal protein lipidation (GO:0006501)2.99470610
126T cell selection (GO:0045058)2.99113007
127regulation of mitochondrial translation (GO:0070129)2.96519233
128positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.96477131
129positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.95371900
130negative thymic T cell selection (GO:0045060)2.94175289
131protein sumoylation (GO:0016925)2.93352280
132regulation of interferon-beta biosynthetic process (GO:0045357)2.92719520
133mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.91576156
134mitochondrial respiratory chain complex I assembly (GO:0032981)2.91576156
135NADH dehydrogenase complex assembly (GO:0010257)2.91576156
136RNA methylation (GO:0001510)2.91421871
137regulation of mast cell activation involved in immune response (GO:0033006)2.91023628
138isoprenoid biosynthetic process (GO:0008299)2.90420114
139long-chain fatty acid biosynthetic process (GO:0042759)2.90050899
140poly(A)+ mRNA export from nucleus (GO:0016973)2.89510930
141regulation of type 2 immune response (GO:0002828)2.88996639
142detection of biotic stimulus (GO:0009595)2.88807414
143respiratory burst (GO:0045730)2.88315097
144negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.86948548
145negative regulation of ligase activity (GO:0051352)2.86948548
146guanosine-containing compound biosynthetic process (GO:1901070)2.86282820
147cholesterol biosynthetic process (GO:0006695)2.85805723
148JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.85318463
149negative regulation of granulocyte differentiation (GO:0030853)2.84635958
150histone H3-K36 demethylation (GO:0070544)2.83866551
151regulation of B cell differentiation (GO:0045577)2.83748694
152response to host immune response (GO:0052572)2.82778063
153response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.82778063
154regulation of granulocyte differentiation (GO:0030852)2.81734700
155intracellular estrogen receptor signaling pathway (GO:0030520)2.80530361
156nuclear-transcribed mRNA catabolic process (GO:0000956)2.79825158
157pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.79692219
158positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.79642990
159regulation of ARF protein signal transduction (GO:0032012)2.79115479
160purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.79047296
161detection of light stimulus involved in sensory perception (GO:0050962)2.78973862
162detection of light stimulus involved in visual perception (GO:0050908)2.78973862
163neutrophil mediated immunity (GO:0002446)2.78371807
164positive regulation of granulocyte differentiation (GO:0030854)2.78021625
165microtubule polymerization or depolymerization (GO:0031109)2.77406440
166histone H3-K9 demethylation (GO:0033169)2.77333251
167regulation of cellular amino acid metabolic process (GO:0006521)2.76672221
168regulation of regulated secretory pathway (GO:1903305)2.76247352
169microtubule depolymerization (GO:0007019)2.75951042
170anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.75377897
171protein complex biogenesis (GO:0070271)2.74929577
172myeloid cell activation involved in immune response (GO:0002275)2.74585920
173dopamine biosynthetic process (GO:0042416)2.74536287
174positive regulation of viral transcription (GO:0050434)2.74095054
175negative regulation of toll-like receptor signaling pathway (GO:0034122)2.74024978
176single strand break repair (GO:0000012)2.73612564
177regulation of phospholipid biosynthetic process (GO:0071071)2.72155927
178negative T cell selection (GO:0043383)2.72069095
179CTP metabolic process (GO:0046036)2.71858491
180positive regulation of cellular amide metabolic process (GO:0034250)2.70603607
181negative regulation of innate immune response (GO:0045824)2.70049582
182immunoglobulin mediated immune response (GO:0016064)2.69798594
183negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.69783049
184regulation of necroptotic process (GO:0060544)2.66941377
185histone H3 deacetylation (GO:0070932)2.66779196
186modulation by virus of host process (GO:0019054)2.64088974
187positive regulation of mast cell activation (GO:0033005)2.63388435
188positive regulation of Rap GTPase activity (GO:0032854)2.62771194
189response to host (GO:0075136)2.62740099
190response to host defenses (GO:0052200)2.62740099
191response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.62740099
192negative regulation of necroptotic process (GO:0060546)2.61074345
193negative regulation of myotube differentiation (GO:0010832)2.60550476
194macrophage activation (GO:0042116)2.59989327
195NIK/NF-kappaB signaling (GO:0038061)2.58480786
196actin filament polymerization (GO:0030041)2.56853065
197creatine metabolic process (GO:0006600)2.55725419
198negative regulation of cytokine production involved in immune response (GO:0002719)2.54999155
199lipopolysaccharide-mediated signaling pathway (GO:0031663)2.54844475
200histone lysine demethylation (GO:0070076)2.52222443

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human5.25497861
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.63696436
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.38902958
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.95156873
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.79595357
6VDR_21846776_ChIP-Seq_THP-1_Human3.77646623
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.57854088
8MYC_18555785_ChIP-Seq_MESCs_Mouse3.51762650
9MYC_22102868_ChIP-Seq_BL_Human3.27894405
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.07556883
11ETS1_20019798_ChIP-Seq_JURKAT_Human3.04023772
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.96256740
13CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.92077139
14KDM2B_26808549_Chip-Seq_SUP-B15_Human2.79305977
15EZH2_22144423_ChIP-Seq_EOC_Human2.74874412
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.73144717
17KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.70307383
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.69599547
19KDM2B_26808549_Chip-Seq_DND41_Human2.66660711
20LXR_22292898_ChIP-Seq_THP-1_Human2.63428712
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.60117395
22TCF7_22412390_ChIP-Seq_EML_Mouse2.60013180
23IRF8_22096565_ChIP-ChIP_GC-B_Human2.57191018
24BP1_19119308_ChIP-ChIP_Hs578T_Human2.52931345
25CREB1_15753290_ChIP-ChIP_HEK293T_Human2.45441580
26TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.45158635
27MAF_26560356_Chip-Seq_TH1_Human2.40330462
28VDR_24763502_ChIP-Seq_THP-1_Human2.34306168
29KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.33724850
30KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.33724850
31KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.33724850
32MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.32018862
33THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.30217369
34MYC_18358816_ChIP-ChIP_MESCs_Mouse2.24939199
35KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.19483054
36MYC_19030024_ChIP-ChIP_MESCs_Mouse2.18460013
37E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.17497236
38MAF_26560356_Chip-Seq_TH2_Human2.15854969
39UTX_26944678_Chip-Seq_JUKART_Human2.15295892
40SCL_19346495_ChIP-Seq_HPC-7_Human2.13778284
41MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.12364423
42MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.07438529
43ELK3_25401928_ChIP-Seq_HUVEC_Human2.02917670
44STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.00487771
45NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.98594838
46NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.94826882
47EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.91167692
48RUNX1_22412390_ChIP-Seq_EML_Mouse1.86681874
49SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.86385102
50YY1_21170310_ChIP-Seq_MESCs_Mouse1.82904829
51P68_20966046_ChIP-Seq_HELA_Human1.82413552
52XRN2_22483619_ChIP-Seq_HELA_Human1.81167002
53RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.80881712
54ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.80393893
55KDM2B_26808549_Chip-Seq_K562_Human1.79891674
56KDM2B_26808549_Chip-Seq_JURKAT_Human1.79855723
57E2F4_17652178_ChIP-ChIP_JURKAT_Human1.78282822
58SPI1_23127762_ChIP-Seq_K562_Human1.76478699
59VDR_23849224_ChIP-Seq_CD4+_Human1.74983345
60SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.74616163
61VDR_22108803_ChIP-Seq_LS180_Human1.74395433
62VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.73486106
63THAP11_20581084_ChIP-Seq_MESCs_Mouse1.71513094
64PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.70052773
65EGR1_19374776_ChIP-ChIP_THP-1_Human1.69992829
66CTCF_27219007_Chip-Seq_ERYTHROID_Human1.69315849
67E2F7_22180533_ChIP-Seq_HELA_Human1.69307421
68RACK7_27058665_Chip-Seq_MCF-7_Human1.69208618
69POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.67716505
70BRD4_27068464_Chip-Seq_AML-cells_Mouse1.66907691
71ELF1_17652178_ChIP-ChIP_JURKAT_Human1.66613963
72MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.66377984
73E2F1_18555785_ChIP-Seq_MESCs_Mouse1.65396583
74GATA1_19941827_ChIP-Seq_MEL_Mouse1.64195415
75TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.64045427
76TTF2_22483619_ChIP-Seq_HELA_Human1.63135444
77IRF1_19129219_ChIP-ChIP_H3396_Human1.61197427
78NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.60457195
79ELK1_19687146_ChIP-ChIP_HELA_Human1.60012137
80SRF_21415370_ChIP-Seq_HL-1_Mouse1.58342205
81DCP1A_22483619_ChIP-Seq_HELA_Human1.57614770
82SA1_27219007_Chip-Seq_ERYTHROID_Human1.56524402
83MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.56205378
84NCOR1_26117541_ChIP-Seq_K562_Human1.55752721
85POU5F1_16153702_ChIP-ChIP_HESCs_Human1.54170149
86EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.53706532
87SMC4_20622854_ChIP-Seq_HELA_Human1.52258763
88BCOR_27268052_Chip-Seq_Bcells_Human1.52163198
89ELF1_20517297_ChIP-Seq_JURKAT_Human1.50883934
90GATA1_19941826_ChIP-Seq_K562_Human1.49745430
91STAT6_21828071_ChIP-Seq_BEAS2B_Human1.48433065
92BCL6_27268052_Chip-Seq_Bcells_Human1.47202730
93GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.44397264
94SPI1_23547873_ChIP-Seq_NB4_Human1.44319945
95FOXP3_21729870_ChIP-Seq_TREG_Human1.44300580
96GATA1_22383799_ChIP-Seq_G1ME_Mouse1.43945287
97EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.43456009
98BMI1_23680149_ChIP-Seq_NPCS_Mouse1.40682551
99ZFP281_18757296_ChIP-ChIP_E14_Mouse1.40329178
100CIITA_25753668_ChIP-Seq_RAJI_Human1.39826981
101DNAJC2_21179169_ChIP-ChIP_NT2_Human1.39807367
102IRF8_21731497_ChIP-ChIP_J774_Mouse1.38656297
103PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.38485677
104MYB_26560356_Chip-Seq_TH1_Human1.37147441
105NANOG_18555785_ChIP-Seq_MESCs_Mouse1.36737702
106RUNX_20019798_ChIP-Seq_JUKART_Human1.35760437
107TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35697590
108CREB1_26743006_Chip-Seq_LNCaP_Human1.35417889
109KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.34464132
110IRF8_27001747_Chip-Seq_BMDM_Mouse1.34054221
111GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33877476
112MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.33705961
113FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.33360532
114MYB_21317192_ChIP-Seq_ERMYB_Mouse1.32413242
115MYC_18940864_ChIP-ChIP_HL60_Human1.32190651
116POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.32146429
117PU.1_20513432_ChIP-Seq_Bcells_Mouse1.30979307
118ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.30882999
119STAT4_19710469_ChIP-ChIP_TH1__Mouse1.29516550
120TET1_21451524_ChIP-Seq_MESCs_Mouse1.28737323
121MYB_26560356_Chip-Seq_TH2_Human1.28132107
122FUS_26573619_Chip-Seq_HEK293_Human1.26634674
123ELK1_22589737_ChIP-Seq_MCF10A_Human1.24913215
124ZFP57_27257070_Chip-Seq_ESCs_Mouse1.24274715
125FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.22986350
126CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.21463300
127TAF15_26573619_Chip-Seq_HEK293_Human1.21374416
128GATA1_26923725_Chip-Seq_HPCs_Mouse1.20762203
129NELFA_20434984_ChIP-Seq_ESCs_Mouse1.19968838
130CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.19489333
131SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.18103278
132CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.17803994
133CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.17110393
134NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.17087359
135CTCF_21964334_ChIP-Seq_BJAB-B_Human1.17041882
136TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.15701024
137PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.14708045
138CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.13962492
139SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.13379386
140GATA2_22383799_ChIP-Seq_G1ME_Mouse1.12937572
141PHF8_20622854_ChIP-Seq_HELA_Human1.12363934
142PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.11497191
143RARG_19884340_ChIP-ChIP_MEFs_Mouse1.09601456
144SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09180776
145MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.07989988
146ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.07540763
147E2F1_20622854_ChIP-Seq_HELA_Human1.07079177
148RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06668398
149CTCF_21964334_Chip-Seq_Bcells_Human1.06503909
150CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06484219
151GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.05953043
152FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.05754418
153UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.05052735
154SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04677248
155YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.04633249
156TP63_19390658_ChIP-ChIP_HaCaT_Human1.02797228
157DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.02762925
158SOX2_16153702_ChIP-ChIP_HESCs_Human1.02499123
159TCF3_18692474_ChIP-Seq_MEFs_Mouse1.02317097
160NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.02118482
161LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.01631686
162CBX2_27304074_Chip-Seq_ESCs_Mouse1.01421627
163RUNX1_27514584_Chip-Seq_MCF-7_Human1.01211937
164SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00882550
165CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00815537
166PADI4_21655091_ChIP-ChIP_MCF-7_Human1.00706961
167HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.99894102
168TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.99755578
169IKZF1_21737484_ChIP-ChIP_HCT116_Human0.99505095
170FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.98645837
171CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.98533218
172SALL1_21062744_ChIP-ChIP_HESCs_Human0.98451347
173ERG_21242973_ChIP-ChIP_JURKAT_Human0.98154868
174GBX2_23144817_ChIP-Seq_PC3_Human0.97846370
175OCT4_19829295_ChIP-Seq_ESCs_Human0.97413979
176CTCF_26484167_Chip-Seq_Bcells_Mouse0.97241976
177MYCN_18555785_ChIP-Seq_MESCs_Mouse0.97177163
178GABP_19822575_ChIP-Seq_HepG2_Human0.96642878
179NANOG_16153702_ChIP-ChIP_HESCs_Human0.96229605
180STAT1_20625510_ChIP-Seq_HELA_Human0.94312807
181POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.93864259
182SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.93591808
183NOTCH1_21737748_ChIP-Seq_TLL_Human0.93458939
184CTBP1_25329375_ChIP-Seq_LNCAP_Human0.92452607
185* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.87264808
186CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.86899749
187POU5F1_16518401_ChIP-PET_MESCs_Mouse0.85725411
188SOX17_20123909_ChIP-Seq_XEN_Mouse0.85267187
189NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.84048061
190OCT4_18692474_ChIP-Seq_MEFs_Mouse0.82995334
191CTCF_18555785_ChIP-Seq_MESCs_Mouse0.81364630
192RNF2_27304074_Chip-Seq_NSC_Mouse0.80881110
193YY1_22570637_ChIP-Seq_MALME-3M_Human0.79233586
194SOX2_18692474_ChIP-Seq_MEFs_Mouse0.78714351
195KAP1_22055183_ChIP-Seq_ESCs_Mouse0.77302137
196CTBP2_25329375_ChIP-Seq_LNCAP_Human0.76536982
197FLI1_27457419_Chip-Seq_LIVER_Mouse0.76205120
198NANOG_18692474_ChIP-Seq_MEFs_Mouse0.73878367
199EWS_26573619_Chip-Seq_HEK293_Human0.72217902
200SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.71454687

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005423_abnormal_somatic_nervous5.67402117
2MP0000566_synostosis4.94951431
3MP0001986_abnormal_taste_sensitivity4.71534745
4MP0009379_abnormal_foot_pigmentation4.45438810
5MP0003303_peritoneal_inflammation4.07778207
6MP0003136_yellow_coat_color3.80648494
7MP0003436_decreased_susceptibility_to3.70306879
8MP0009278_abnormal_bone_marrow3.32696743
9MP0004145_abnormal_muscle_electrophysio3.12102382
10MP0006292_abnormal_olfactory_placode2.96166836
11MP0003880_abnormal_central_pattern2.94596020
12MP0003724_increased_susceptibility_to2.93886038
13MP0001529_abnormal_vocalization2.67406807
14MP0001905_abnormal_dopamine_level2.49292743
15MP0003172_abnormal_lysosome_physiology2.48522469
16MP0008057_abnormal_DNA_replication2.47713821
17MP0002419_abnormal_innate_immunity2.43194611
18MP0005409_darkened_coat_color2.36497344
19MP0001835_abnormal_antigen_presentation2.32234097
20MP0005025_abnormal_response_to2.29695829
21MP0008260_abnormal_autophagy2.23697288
22MP0003718_maternal_effect2.23368856
23MP0001800_abnormal_humoral_immune2.18471876
24MP0005058_abnormal_lysosome_morphology2.14415770
25MP0000685_abnormal_immune_system2.14083306
26MP0005000_abnormal_immune_tolerance2.12552050
27MP0003763_abnormal_thymus_physiology2.06901203
28MP0002396_abnormal_hematopoietic_system2.06466071
29MP0002420_abnormal_adaptive_immunity2.01952036
30MP0001819_abnormal_immune_cell1.99129407
31MP0002723_abnormal_immune_serum1.98534618
32MP0005387_immune_system_phenotype1.96110438
33MP0001790_abnormal_immune_system1.96110438
34MP0004130_abnormal_muscle_cell1.95367577
35MP0004133_heterotaxia1.93574169
36MP0003300_gastrointestinal_ulcer1.91307137
37MP0002132_abnormal_respiratory_system1.91111915
38MP0003693_abnormal_embryo_hatching1.87839756
39MP0004947_skin_inflammation1.87688510
40MP0002452_abnormal_antigen_presenting1.87385801
41MP0002398_abnormal_bone_marrow1.84216529
42MP0005397_hematopoietic_system_phenotyp1.83680147
43MP0001545_abnormal_hematopoietic_system1.83680147
44MP0004381_abnormal_hair_follicle1.80730338
45MP0003191_abnormal_cellular_cholesterol1.74422371
46MP0002822_catalepsy1.71052210
47MP0006276_abnormal_autonomic_nervous1.70015729
48MP0005076_abnormal_cell_differentiation1.69503254
49MP0005464_abnormal_platelet_physiology1.68058675
50MP0009785_altered_susceptibility_to1.66217621
51MP0000716_abnormal_immune_system1.64560721
52MP0008932_abnormal_embryonic_tissue1.63749268
53MP0005410_abnormal_fertilization1.60924358
54MP0003656_abnormal_erythrocyte_physiolo1.59891447
55MP0004142_abnormal_muscle_tone1.58789254
56MP0002405_respiratory_system_inflammati1.57790771
57MP0008877_abnormal_DNA_methylation1.57298987
58MP0005671_abnormal_response_to1.56131152
59MP0004185_abnormal_adipocyte_glucose1.55393238
60MP0009840_abnormal_foam_cell1.55323371
61MP0000703_abnormal_thymus_morphology1.54949545
62MP0002938_white_spotting1.54059963
63MP0001188_hyperpigmentation1.53157575
64MP0008789_abnormal_olfactory_epithelium1.52833431
65MP0002722_abnormal_immune_system1.52613795
66MP0004957_abnormal_blastocyst_morpholog1.52320820
67MP0002102_abnormal_ear_morphology1.51877470
68MP0004270_analgesia1.49833546
69MP0005666_abnormal_adipose_tissue1.48843754
70MP0004510_myositis1.48477741
71MP0000689_abnormal_spleen_morphology1.47897279
72MP0009333_abnormal_splenocyte_physiolog1.47637972
73MP0003828_pulmonary_edema1.47190151
74MP0008058_abnormal_DNA_repair1.45123952
75MP0001486_abnormal_startle_reflex1.42310792
76MP0001440_abnormal_grooming_behavior1.41729289
77MP0003329_amyloid_beta_deposits1.40326926
78MP0002734_abnormal_mechanical_nocicepti1.37514667
79MP0002429_abnormal_blood_cell1.36498734
80MP0005451_abnormal_body_composition1.35946056
81MP0001533_abnormal_skeleton_physiology1.34354089
82MP0003111_abnormal_nucleus_morphology1.34071774
83MP0003950_abnormal_plasma_membrane1.33679481
84MP0003938_abnormal_ear_development1.33643496
85MP0005083_abnormal_biliary_tract1.33425836
86MP0002148_abnormal_hypersensitivity_rea1.31914505
87MP0005171_absent_coat_pigmentation1.31036571
88MP0005551_abnormal_eye_electrophysiolog1.29855934
89MP0000372_irregular_coat_pigmentation1.28658811
90MP0002572_abnormal_emotion/affect_behav1.28154686
91MP0003806_abnormal_nucleotide_metabolis1.26082325
92MP0006072_abnormal_retinal_apoptosis1.25197776
93MP0005379_endocrine/exocrine_gland_phen1.24441218
94MP0002272_abnormal_nervous_system1.24253246
95MP0010155_abnormal_intestine_physiology1.23720843
96MP0003077_abnormal_cell_cycle1.18730678
97MP0005394_taste/olfaction_phenotype1.18715798
98MP0005499_abnormal_olfactory_system1.18715798
99MP0005310_abnormal_salivary_gland1.18095518
100MP0003646_muscle_fatigue1.16264665
101MP0003183_abnormal_peptide_metabolism1.13909291
102MP0009745_abnormal_behavioral_response1.13765784
103MP0010094_abnormal_chromosome_stability1.13433979
104MP0004859_abnormal_synaptic_plasticity1.13036467
105MP0001845_abnormal_inflammatory_respons1.12977236
106MP0004742_abnormal_vestibular_system1.12871032
107MP0003690_abnormal_glial_cell1.12847532
108MP0000678_abnormal_parathyroid_gland1.12778424
109MP0002751_abnormal_autonomic_nervous1.12447494
110MP0000604_amyloidosis1.12206698
111MP0000751_myopathy1.10985594
112MP0002998_abnormal_bone_remodeling1.10374915
113MP0003937_abnormal_limbs/digits/tail_de1.10368714
114MP0001485_abnormal_pinna_reflex1.10198143
115MP0001727_abnormal_embryo_implantation1.09989626
116MP0000762_abnormal_tongue_morphology1.07678932
117MP0000778_abnormal_nervous_system1.07420508
118MP0002752_abnormal_somatic_nervous1.07185733
119MP0006082_CNS_inflammation1.06547591
120MP0000858_altered_metastatic_potential1.05587269
121MP0000026_abnormal_inner_ear1.04346940
122MP0005253_abnormal_eye_physiology1.03361231
123MP0000750_abnormal_muscle_regeneration1.03110960
124MP0003866_abnormal_defecation1.03104375
125MP0008469_abnormal_protein_level1.02528957
126MP0001968_abnormal_touch/_nociception1.01692426
127MP0004808_abnormal_hematopoietic_stem1.01194117
128MP0000462_abnormal_digestive_system1.01156826
129MP0003698_abnormal_male_reproductive1.01054296
130MP0003635_abnormal_synaptic_transmissio1.00650037
131MP0005395_other_phenotype1.00467617
132MP0002064_seizures0.99390055
133MP0000920_abnormal_myelination0.99310040
134MP0002210_abnormal_sex_determination0.99036184
135MP0000747_muscle_weakness0.98679943
136MP0002277_abnormal_respiratory_mucosa0.98037577
137MP0003941_abnormal_skin_development0.97929916
138MP0001853_heart_inflammation0.96968435
139MP0005375_adipose_tissue_phenotype0.96627839
140MP0001963_abnormal_hearing_physiology0.95849770
141MP0003221_abnormal_cardiomyocyte_apopto0.95504897
142MP0003890_abnormal_embryonic-extraembry0.94082760
143MP0001929_abnormal_gametogenesis0.93755006
144MP0002249_abnormal_larynx_morphology0.93642895
145MP0010630_abnormal_cardiac_muscle0.93120881
146MP0002971_abnormal_brown_adipose0.92967009
147MP0002009_preneoplasia0.91780482
148MP0002184_abnormal_innervation0.90420025
149MP0002163_abnormal_gland_morphology0.89553379
150MP0006035_abnormal_mitochondrial_morpho0.88772495
151MP0002736_abnormal_nociception_after0.88708227
152MP0001851_eye_inflammation0.86267312
153MP0002067_abnormal_sensory_capabilities0.85312658
154MP0001348_abnormal_lacrimal_gland0.85268500
155MP0002638_abnormal_pupillary_reflex0.83218692
156MP0003075_altered_response_to0.83145366
157MP0001873_stomach_inflammation0.82974081
158MP0001970_abnormal_pain_threshold0.82755197
159MP0005535_abnormal_body_temperature0.82260625
160MP0003453_abnormal_keratinocyte_physiol0.81991601
161MP0002557_abnormal_social/conspecific_i0.81637586
162MP0009046_muscle_twitch0.81475957
163MP0004924_abnormal_behavior0.80152166
164MP0005386_behavior/neurological_phenoty0.80152166
165MP0004087_abnormal_muscle_fiber0.79857926
166MP0003878_abnormal_ear_physiology0.79730508
167MP0005377_hearing/vestibular/ear_phenot0.79730508
168MP0001849_ear_inflammation0.79506771
169MP0009115_abnormal_fat_cell0.79116975
170MP0000465_gastrointestinal_hemorrhage0.78956471
171MP0001145_abnormal_male_reproductive0.78745870
172MP0002063_abnormal_learning/memory/cond0.76961890
173MP0009764_decreased_sensitivity_to0.76740547
174MP0008874_decreased_physiological_sensi0.76596031
175MP0000653_abnormal_sex_gland0.72968132
176MP0003121_genomic_imprinting0.72898688
177MP0002882_abnormal_neuron_morphology0.72508493
178MP0002733_abnormal_thermal_nociception0.71786707
179MP0000049_abnormal_middle_ear0.71279590
180MP0005195_abnormal_posterior_eye0.71029349
181MP0005166_decreased_susceptibility_to0.69389960
182MP0002735_abnormal_chemical_nociception0.68587284
183MP0005408_hypopigmentation0.68035152
184MP0002106_abnormal_muscle_physiology0.67703718
185MP0008569_lethality_at_weaning0.66868568
186MP0002066_abnormal_motor_capabilities/c0.66333339
187MP0002166_altered_tumor_susceptibility0.66242821
188MP0003091_abnormal_cell_migration0.66220427
189MP0003786_premature_aging0.66145342
190MP0002160_abnormal_reproductive_system0.66064593
191MP0000631_abnormal_neuroendocrine_gland0.65408992
192MP0003315_abnormal_perineum_morphology0.63968397
193MP0003861_abnormal_nervous_system0.63891951
194MP0002229_neurodegeneration0.62509645

Predicted human phenotypes

RankGene SetZ-score
1Duplicated collecting system (HP:0000081)6.27853371
2Abnormality of the renal collecting system (HP:0004742)5.44908734
3Eczematoid dermatitis (HP:0000976)5.26951970
4Muscle abnormality related to mitochondrial dysfunction (HP:0003800)4.72077976
5Breast hypoplasia (HP:0003187)4.44425877
6Acute necrotizing encephalopathy (HP:0006965)4.13867776
7Myositis (HP:0100614)4.12013546
8Recurrent abscess formation (HP:0002722)4.11191005
9Recurrent bacterial skin infections (HP:0005406)4.00663127
10Parakeratosis (HP:0001036)3.74719483
11Long foot (HP:0001833)3.72188360
12Abnormality of macrophages (HP:0004311)3.71865190
13Hypoplastic nipples (HP:0002557)3.69036751
14Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.65906618
15Orchitis (HP:0100796)3.65133904
16Acute lymphatic leukemia (HP:0006721)3.59962244
17Reticulocytopenia (HP:0001896)3.57879279
18Congenital stationary night blindness (HP:0007642)3.49096998
19Recurrent gram-negative bacterial infections (HP:0005420)3.47045498
20Increased hepatocellular lipid droplets (HP:0006565)3.45428251
21Optic neuritis (HP:0100653)3.45031523
22Retrobulbar optic neuritis (HP:0100654)3.45031523
23Mitochondrial inheritance (HP:0001427)3.44778157
24Abnormal mitochondria in muscle tissue (HP:0008316)3.40719026
25Abnormality of cells of the erythroid lineage (HP:0012130)3.39244262
26Macrocytic anemia (HP:0001972)3.38356013
27Chronic obstructive pulmonary disease (HP:0006510)3.36157428
28Obstructive lung disease (HP:0006536)3.36157428
29Gastrointestinal infarctions (HP:0005244)3.35617732
30Cellulitis (HP:0100658)3.33352221
31Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.31279440
32Progressive macrocephaly (HP:0004481)3.29173134
33Recurrent fungal infections (HP:0002841)3.28430887
34Renal Fanconi syndrome (HP:0001994)3.27857573
35Elevated erythrocyte sedimentation rate (HP:0003565)3.27612557
36Increased intramyocellular lipid droplets (HP:0012240)3.26337798
37Progressive external ophthalmoplegia (HP:0000590)3.23919060
38Mediastinal lymphadenopathy (HP:0100721)3.23130694
39Panhypogammaglobulinemia (HP:0003139)3.18156605
40Acute encephalopathy (HP:0006846)3.17715115
41Increased IgE level (HP:0003212)3.17649892
42Meningitis (HP:0001287)3.13754801
43Broad-based gait (HP:0002136)3.10920141
44Pulmonary artery stenosis (HP:0004415)3.00589527
45Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.99769410
46Decreased activity of mitochondrial respiratory chain (HP:0008972)2.99769410
47Abnormal number of erythroid precursors (HP:0012131)2.98174855
48Adactyly (HP:0009776)2.98000345
49Colitis (HP:0002583)2.96379039
50Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.93195749
51Transposition of the great arteries (HP:0001669)2.86818243
52Abnormal connection of the cardiac segments (HP:0011545)2.86818243
53Abnormal ventriculo-arterial connection (HP:0011563)2.86818243
54Cerebral hypomyelination (HP:0006808)2.85358530
55Lipid accumulation in hepatocytes (HP:0006561)2.83940638
56Large for gestational age (HP:0001520)2.83920730
57Abnormality of glycolysis (HP:0004366)2.83647917
58Increased serum pyruvate (HP:0003542)2.83647917
59Ureteral duplication (HP:0000073)2.81271865
60Slow saccadic eye movements (HP:0000514)2.80822881
61Gingivitis (HP:0000230)2.80679010
62Increased CSF lactate (HP:0002490)2.77907894
63Aplasia/Hypoplasia of the sacrum (HP:0008517)2.74641587
64Abnormality of the fingertips (HP:0001211)2.70660436
65Exercise intolerance (HP:0003546)2.70442495
663-Methylglutaconic aciduria (HP:0003535)2.68226995
67Abnormality of the axillary hair (HP:0100134)2.67748937
68Abnormality of secondary sexual hair (HP:0009888)2.67748937
69Optic disc pallor (HP:0000543)2.66817108
70Stomatitis (HP:0010280)2.66719472
71Abnormality of placental membranes (HP:0011409)2.65152836
72Amniotic constriction ring (HP:0009775)2.65152836
73Exercise-induced myalgia (HP:0003738)2.64442630
74Birth length less than 3rd percentile (HP:0003561)2.63753811
75Leukodystrophy (HP:0002415)2.60894635
76Keratoconjunctivitis sicca (HP:0001097)2.60750730
77Gastrointestinal inflammation (HP:0004386)2.59779497
78Prolonged bleeding time (HP:0003010)2.58227570
79Ragged-red muscle fibers (HP:0003200)2.55925208
80Recurrent skin infections (HP:0001581)2.54785669
81Hepatocellular necrosis (HP:0001404)2.54276341
82Aplasia/Hypoplasia involving the musculature (HP:0001460)2.53066971
83Aplasia of the musculature (HP:0100854)2.52026131
84Pallor (HP:0000980)2.50401111
85Increased muscle lipid content (HP:0009058)2.47568921
86Hypochromic anemia (HP:0001931)2.44022650
87Inflammation of the large intestine (HP:0002037)2.42056026
88Chest pain (HP:0100749)2.41707289
89Asymmetric septal hypertrophy (HP:0001670)2.40705984
90Recurrent viral infections (HP:0004429)2.39260842
91Granulocytopenia (HP:0001913)2.38807468
92Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.36854121
93Keratoconjunctivitis (HP:0001096)2.32936353
94Encephalitis (HP:0002383)2.31555844
95Overfolded helix (HP:0000396)2.31451849
96Increased serum lactate (HP:0002151)2.30156297
97Spontaneous hematomas (HP:0007420)2.29529391
98Hemorrhage of the eye (HP:0011885)2.28961156
99Congenital ichthyosiform erythroderma (HP:0007431)2.27868789
100Absent/shortened dynein arms (HP:0200106)2.27444852
101Dynein arm defect of respiratory motile cilia (HP:0012255)2.27444852
102Vasculitis (HP:0002633)2.26662636
103Abnormal delayed hypersensitivity skin test (HP:0002963)2.25768527
104Conical tooth (HP:0000698)2.25001933
105Annular pancreas (HP:0001734)2.22450381
106Reticulocytosis (HP:0001923)2.22217197
107Cerebral edema (HP:0002181)2.20032586
108Bowel incontinence (HP:0002607)2.18444540
109Recurrent cutaneous fungal infections (HP:0011370)2.17947205
110Chronic mucocutaneous candidiasis (HP:0002728)2.17947205
111Abnormality of renal resorption (HP:0011038)2.17454987
112Epistaxis (HP:0000421)2.16525239
113Exertional dyspnea (HP:0002875)2.16507012
114Myopathic facies (HP:0002058)2.16132364
115Arterial thrombosis (HP:0004420)2.16011660
116Centrally nucleated skeletal muscle fibers (HP:0003687)2.15641472
117Abnormality of the labia minora (HP:0012880)2.15181213
118Neuronal loss in central nervous system (HP:0002529)2.12905668
119Adrenal hypoplasia (HP:0000835)2.09957161
120Ankle clonus (HP:0011448)2.09491313
121Pustule (HP:0200039)2.09374288
122Hypoplasia of the thymus (HP:0000778)2.08248070
123Obstructive sleep apnea (HP:0002870)2.08193766
124Abnormal respiratory motile cilium morphology (HP:0005938)2.07413081
125Abnormal respiratory epithelium morphology (HP:0012253)2.07413081
126Episodic fever (HP:0001954)2.06781070
127Increased cerebral lipofuscin (HP:0011813)2.06230716
128Hypoplastic pelvis (HP:0008839)2.05808186
129Rough bone trabeculation (HP:0100670)2.05502480
130Abnormal large intestine physiology (HP:0012700)2.04820686
131Supernumerary spleens (HP:0009799)2.03089099
132Muscle fiber splitting (HP:0003555)2.02968063
133Difficulty running (HP:0009046)2.02362437
134Abdominal situs inversus (HP:0003363)2.01815715
135Abnormality of abdominal situs (HP:0011620)2.01815715
136Attenuation of retinal blood vessels (HP:0007843)2.00886438
137Septo-optic dysplasia (HP:0100842)2.00117620
138Aplasia/Hypoplasia of the thymus (HP:0010515)1.98427277
139External ophthalmoplegia (HP:0000544)1.97760420
140Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.97700665
141Interstitial pulmonary disease (HP:0006530)1.97461468
142Abnormal ciliary motility (HP:0012262)1.97174885
143Thoracic kyphosis (HP:0002942)1.97039491
144Amyloidosis (HP:0011034)1.96548962
145Leukocytosis (HP:0001974)1.96096537
146Increased serum ferritin (HP:0003281)1.94998498
147Segmental peripheral demyelination/remyelination (HP:0003481)1.94901745
148Absent radius (HP:0003974)1.94396722
149Abnormally folded helix (HP:0008544)1.94167925
150Concave nail (HP:0001598)1.93991181
151Urticaria (HP:0001025)1.93953286
152Acute hepatic failure (HP:0006554)1.93759568
153Aplasia/Hypoplasia of the nipples (HP:0006709)1.92152494
154Absent forearm bone (HP:0003953)1.91775211
155Aplasia involving forearm bones (HP:0009822)1.91775211
156Metaphyseal cupping (HP:0003021)1.91368971
157Purpura (HP:0000979)1.90562560
158Agammaglobulinemia (HP:0004432)1.90380299
159Hepatic necrosis (HP:0002605)1.89509905
160Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.88396239
161Degeneration of the lateral corticospinal tracts (HP:0002314)1.88396239
162Delusions (HP:0000746)1.87412863
163Polycythemia (HP:0001901)1.84894882
164Peripheral hypomyelination (HP:0007182)1.84859212
165Abnormal respiratory motile cilium physiology (HP:0012261)1.84264867
166Lactic acidosis (HP:0003128)1.83799022
167Osteomyelitis (HP:0002754)1.82556664
168Abnormality of the thoracic spine (HP:0100711)1.82484720
169Respiratory failure (HP:0002878)1.81853607
170Hypertriglyceridemia (HP:0002155)1.81623447
171Aplasia/hypoplasia of the uterus (HP:0008684)1.81557636
172Polygenic inheritance (HP:0010982)1.81447719
173Sepsis (HP:0100806)1.79671464
174Viral hepatitis (HP:0006562)1.78696080
175Subaortic stenosis (HP:0001682)1.78668278
176Abnormality of the left ventricular outflow tract (HP:0011103)1.78668278
177Hypertensive crisis (HP:0100735)1.78639730
178Loss of speech (HP:0002371)1.78518247
179Aplasia/Hypoplasia of the earlobes (HP:0009906)1.78273387
180Abnormality of the endocardium (HP:0004306)1.77922269
181Respiratory difficulties (HP:0002880)1.77049612
182Hypochromic microcytic anemia (HP:0004840)1.77002756
183Supranuclear gaze palsy (HP:0000605)1.76725186
184Vertigo (HP:0002321)1.76440795
185Oral leukoplakia (HP:0002745)1.76050589
186Carpal bone hypoplasia (HP:0001498)1.74765357
187Hemoptysis (HP:0002105)1.74738392
188Horseshoe kidney (HP:0000085)1.74181804
189Abnormality of glycolipid metabolism (HP:0010969)1.73360208
190Abnormality of liposaccharide metabolism (HP:0010968)1.73360208
191Abnormality of glycosphingolipid metabolism (HP:0004343)1.73360208
192Hypercortisolism (HP:0001578)1.72991483
193Truncus arteriosus (HP:0001660)1.72939136
194CNS hypomyelination (HP:0003429)1.72640218
195Rapidly progressive (HP:0003678)1.71627805
196Thin bony cortex (HP:0002753)1.71502044
197Patellar aplasia (HP:0006443)1.70881409
198Limb dystonia (HP:0002451)1.69915412
199Asplenia (HP:0001746)1.69897065

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.08960279
2PRPF4B3.39471993
3RIPK43.38692696
4BUB13.29321087
5TRIB33.18463911
6MAP2K32.90215583
7PNCK2.80955175
8MAP4K12.64797555
9MARK12.59435677
10STK392.38365236
11ERN12.35807338
12IRAK32.24533494
13CASK2.16387291
14SRPK12.16098475
15TNIK2.07000437
16WEE12.05871928
17PLK42.05160032
18BLK2.02344548
19DYRK21.98992279
20FES1.96263930
21SMG11.95424483
22VRK11.92638304
23NME21.91524148
24TNK21.89578841
25KSR21.87142669
26TAOK11.82982106
27MAP3K111.81176772
28MARK21.76375878
29PBK1.74388774
30NME11.73008537
31MKNK21.72351675
32EEF2K1.71594180
33IRAK21.70961742
34TLK11.63318701
35OXSR11.56315717
36MAP3K11.55620906
37GRK61.54415135
38CSK1.52718277
39TYK21.52124483
40CDC42BPA1.49666576
41MKNK11.49538797
42ZAP701.49418898
43DYRK31.48653994
44CLK11.47689511
45MAP3K131.46931885
46BTK1.42563669
47EPHB11.39676386
48CDK121.39246839
49ZAK1.38058559
50TTK1.37759848
51FGFR41.37742978
52EIF2AK11.37205750
53MST41.36956819
54ADRBK21.36290430
55MAP3K71.27870326
56TBK11.27717958
57PKN11.27619090
58CDK191.27110373
59ROCK21.26947891
60HCK1.25548315
61BCR1.24331446
62SIK11.23694816
63TAOK21.23032212
64ICK1.22811113
65EIF2AK31.22765328
66NEK61.22412460
67DYRK1B1.22288925
68CSNK1G31.14766610
69UHMK11.12774241
70MAPKAPK51.12451234
71SIK21.12232069
72MAPK121.12090862
73SYK1.11159828
74PRKD21.11119199
75JAK21.10798760
76MAP2K71.10680809
77MAP3K101.10333966
78MAP3K31.09150683
79EPHA21.07879356
80CAMK2B1.06054303
81IRAK41.04649748
82JAK31.04636416
83MAP3K141.03331370
84PDPK11.03323978
85AURKA1.02724786
86PKN21.02696175
87TTN1.00989660
88CDC71.00880524
89CSNK1G11.00226485
90IRAK10.99264094
91RPS6KC10.99137030
92RPS6KL10.99137030
93YES10.98962146
94MAPK130.98145286
95GRK70.97868642
96HIPK20.95517306
97CAMKK10.92920654
98PDK10.91927259
99TYRO30.91478898
100RPS6KB20.90055871
101MAP3K60.89477798
102PTK60.89469257
103RIPK10.86767956
104PLK10.84750425
105RPS6KA20.83922287
106BRAF0.83518429
107IKBKE0.82421992
108RPS6KA50.80986847
109RPS6KA60.78702919
110PLK30.78422809
111EIF2AK20.77721511
112EPHA40.77340189
113TAOK30.77086594
114SGK30.75537679
115LYN0.74946715
116MAP3K40.74506057
117RET0.73824299
118MUSK0.73581922
119CAMK2A0.73063533
120WNK40.71766518
121MATK0.71026593
122ITK0.70496062
123CSNK2A20.70296886
124CSNK1A1L0.69648593
125ABL20.69375480
126FGR0.68748123
127BMPR1B0.68303586
128TESK20.67588758
129FGFR30.67534045
130LCK0.66739473
131MAP2K40.65314455
132BRD40.64477792
133CHEK20.64295766
134CAMK2D0.64147779
135CSNK1G20.63234182
136BMPR20.62853680
137EPHA30.62397838
138CDK30.62203360
139BCKDK0.62182569
140PAK10.61679259
141MARK30.61253524
142MAPK110.60954743
143GRK10.60083167
144CSNK1E0.60024884
145BMX0.59643672
146MAPK70.59514777
147GRK50.59093418
148CAMK2G0.59045285
149ARAF0.58873567
150CAMK40.58856978
151CDK40.58482116
152CSF1R0.58166469
153CSNK2A10.57960443
154RAF10.57877156
155CDK70.57688114
156MTOR0.57476045
157AKT30.57414785
158PRKCI0.57235932
159PAK60.56839959
160TSSK60.56706471
161CDK11A0.54706843
162STK110.54396085
163JAK10.54225889
164ERBB40.53856286
165ATR0.53108793
166STK380.50941117
167PLK20.50924665
168ADRBK10.50447984
169MAP3K90.50239677
170RPS6KA10.49858323
171CDK140.49749916
172CHEK10.49510949
173CDK150.49065890
174LRRK20.48448575
175LATS20.47810080
176MAPK40.47798201
177CDK180.46992355
178SIK30.45399847
179KSR10.44929521
180PIM10.44851079
181LIMK10.44062761
182IKBKB0.43508741
183MAPK150.42415140
184SGK2230.42338650
185MAP2K20.41477112
186PRKACA0.41430565
187PRKCG0.40373228
188DYRK1A0.39470651
189PIM20.38874686
190PRKCE0.38086631

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.28704987
2RNA polymerase_Homo sapiens_hsa030204.15747870
3Oxidative phosphorylation_Homo sapiens_hsa001904.12802205
4Proteasome_Homo sapiens_hsa030503.67922324
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.52047844
6Parkinsons disease_Homo sapiens_hsa050123.39476915
7Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.07791605
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.87951016
9Huntingtons disease_Homo sapiens_hsa050162.75040410
10Alzheimers disease_Homo sapiens_hsa050102.54006493
11Pyrimidine metabolism_Homo sapiens_hsa002402.46998710
12Spliceosome_Homo sapiens_hsa030402.45171733
13B cell receptor signaling pathway_Homo sapiens_hsa046622.44544478
14Mismatch repair_Homo sapiens_hsa034302.38130680
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.38012178
16Acute myeloid leukemia_Homo sapiens_hsa052212.37638769
17Other glycan degradation_Homo sapiens_hsa005112.35855416
18Osteoclast differentiation_Homo sapiens_hsa043802.33697178
19DNA replication_Homo sapiens_hsa030302.23835514
20Phototransduction_Homo sapiens_hsa047442.19614471
21Fanconi anemia pathway_Homo sapiens_hsa034602.07411945
22Leishmaniasis_Homo sapiens_hsa051402.04136518
23Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046662.03207201
24Protein export_Homo sapiens_hsa030601.97359204
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.96931548
26Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.95838445
27Nucleotide excision repair_Homo sapiens_hsa034201.80508094
28Basal transcription factors_Homo sapiens_hsa030221.79589045
29Homologous recombination_Homo sapiens_hsa034401.79025296
30Non-small cell lung cancer_Homo sapiens_hsa052231.78500256
31RNA transport_Homo sapiens_hsa030131.75726240
32VEGF signaling pathway_Homo sapiens_hsa043701.69954517
33Cardiac muscle contraction_Homo sapiens_hsa042601.65472834
34Staphylococcus aureus infection_Homo sapiens_hsa051501.63932775
35Tuberculosis_Homo sapiens_hsa051521.58349466
36Chronic myeloid leukemia_Homo sapiens_hsa052201.57299992
37Purine metabolism_Homo sapiens_hsa002301.53607818
38Primary immunodeficiency_Homo sapiens_hsa053401.53370306
39Fatty acid elongation_Homo sapiens_hsa000621.52069680
40T cell receptor signaling pathway_Homo sapiens_hsa046601.50869739
41Notch signaling pathway_Homo sapiens_hsa043301.50700849
42Toll-like receptor signaling pathway_Homo sapiens_hsa046201.49907210
43Neurotrophin signaling pathway_Homo sapiens_hsa047221.44361698
44Steroid biosynthesis_Homo sapiens_hsa001001.44295217
45Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.38083665
46RNA degradation_Homo sapiens_hsa030181.37767634
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.36075667
48mTOR signaling pathway_Homo sapiens_hsa041501.29815648
49Pancreatic cancer_Homo sapiens_hsa052121.26117401
50Chemokine signaling pathway_Homo sapiens_hsa040621.25784103
51NOD-like receptor signaling pathway_Homo sapiens_hsa046211.24219059
52Ether lipid metabolism_Homo sapiens_hsa005651.24070787
53Renal cell carcinoma_Homo sapiens_hsa052111.22057369
54Glycosaminoglycan degradation_Homo sapiens_hsa005311.21362268
55GnRH signaling pathway_Homo sapiens_hsa049121.18080043
56Influenza A_Homo sapiens_hsa051641.17898339
57Endometrial cancer_Homo sapiens_hsa052131.17558647
58RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.17082725
59Carbohydrate digestion and absorption_Homo sapiens_hsa049731.16727682
60Prolactin signaling pathway_Homo sapiens_hsa049171.14453022
61Hepatitis B_Homo sapiens_hsa051611.12600910
62Jak-STAT signaling pathway_Homo sapiens_hsa046301.12215676
63Measles_Homo sapiens_hsa051621.10632373
64Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09673802
65Linoleic acid metabolism_Homo sapiens_hsa005911.09649789
66NF-kappa B signaling pathway_Homo sapiens_hsa040641.08814412
67Adipocytokine signaling pathway_Homo sapiens_hsa049201.08722275
68Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.07609657
69Non-homologous end-joining_Homo sapiens_hsa034501.06901112
70ErbB signaling pathway_Homo sapiens_hsa040121.06157478
71Long-term potentiation_Homo sapiens_hsa047201.05070817
72Inositol phosphate metabolism_Homo sapiens_hsa005621.04424870
73Insulin signaling pathway_Homo sapiens_hsa049101.04246688
74Phospholipase D signaling pathway_Homo sapiens_hsa040721.03460396
75Toxoplasmosis_Homo sapiens_hsa051451.02655861
76Herpes simplex infection_Homo sapiens_hsa051681.01718121
77Choline metabolism in cancer_Homo sapiens_hsa052311.01528566
78Hepatitis C_Homo sapiens_hsa051601.01489031
79Platelet activation_Homo sapiens_hsa046110.97583452
80Malaria_Homo sapiens_hsa051440.97262473
81Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.97132531
82Fructose and mannose metabolism_Homo sapiens_hsa000510.96016843
83TNF signaling pathway_Homo sapiens_hsa046680.94622971
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.94431425
85Viral carcinogenesis_Homo sapiens_hsa052030.93678751
86AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.93474530
87MAPK signaling pathway_Homo sapiens_hsa040100.93240144
88Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.91472975
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.91362468
90One carbon pool by folate_Homo sapiens_hsa006700.90791752
91Viral myocarditis_Homo sapiens_hsa054160.89868405
92Nicotine addiction_Homo sapiens_hsa050330.89365902
93Glutathione metabolism_Homo sapiens_hsa004800.88490701
94Insulin resistance_Homo sapiens_hsa049310.87981300
95Graft-versus-host disease_Homo sapiens_hsa053320.87633390
96Allograft rejection_Homo sapiens_hsa053300.87154169
97Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.86636484
98Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.86626794
99Leukocyte transendothelial migration_Homo sapiens_hsa046700.86061417
100Glioma_Homo sapiens_hsa052140.85885158
101Colorectal cancer_Homo sapiens_hsa052100.85141002
102Type II diabetes mellitus_Homo sapiens_hsa049300.84436232
103Arachidonic acid metabolism_Homo sapiens_hsa005900.84294003
104FoxO signaling pathway_Homo sapiens_hsa040680.84096010
105Epstein-Barr virus infection_Homo sapiens_hsa051690.82750686
106Collecting duct acid secretion_Homo sapiens_hsa049660.82161469
107HIF-1 signaling pathway_Homo sapiens_hsa040660.82023079
108Endocytosis_Homo sapiens_hsa041440.81668972
109Longevity regulating pathway - mammal_Homo sapiens_hsa042110.81094189
110Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.80497398
111Base excision repair_Homo sapiens_hsa034100.79172965
112Cell cycle_Homo sapiens_hsa041100.78377157
113alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.78081034
114Metabolic pathways_Homo sapiens_hsa011000.76916105
115Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.76779184
116Arginine and proline metabolism_Homo sapiens_hsa003300.74971483
117Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74968987
118Central carbon metabolism in cancer_Homo sapiens_hsa052300.73886649
119Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.73315429
120Hematopoietic cell lineage_Homo sapiens_hsa046400.72947753
121Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.72793668
122Apoptosis_Homo sapiens_hsa042100.71492545
123Serotonergic synapse_Homo sapiens_hsa047260.71230605
124Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.70682084
125Legionellosis_Homo sapiens_hsa051340.70077703
126Lysosome_Homo sapiens_hsa041420.69982222
127Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.69863054
128Bladder cancer_Homo sapiens_hsa052190.66204751
129Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.65282736
130Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64626514
131Transcriptional misregulation in cancer_Homo sapiens_hsa052020.64150531
132AMPK signaling pathway_Homo sapiens_hsa041520.62637477
133HTLV-I infection_Homo sapiens_hsa051660.61460444
134Vitamin B6 metabolism_Homo sapiens_hsa007500.61391794
135Estrogen signaling pathway_Homo sapiens_hsa049150.61370901
136Antigen processing and presentation_Homo sapiens_hsa046120.61365638
137Shigellosis_Homo sapiens_hsa051310.60367037
138Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.58922011
139Tyrosine metabolism_Homo sapiens_hsa003500.58316262
140Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57881100
141Salmonella infection_Homo sapiens_hsa051320.55820668
142Pentose phosphate pathway_Homo sapiens_hsa000300.55591606
143Pertussis_Homo sapiens_hsa051330.55482015
144Vibrio cholerae infection_Homo sapiens_hsa051100.55030289
145Sphingolipid metabolism_Homo sapiens_hsa006000.55025044
146Prion diseases_Homo sapiens_hsa050200.54741039
147Axon guidance_Homo sapiens_hsa043600.52731622
148Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50132253
149Systemic lupus erythematosus_Homo sapiens_hsa053220.50084037
150Rap1 signaling pathway_Homo sapiens_hsa040150.48721986
151Type I diabetes mellitus_Homo sapiens_hsa049400.47991156
152Thyroid cancer_Homo sapiens_hsa052160.47448241
153Cysteine and methionine metabolism_Homo sapiens_hsa002700.47280291
154Cyanoamino acid metabolism_Homo sapiens_hsa004600.47087103
155Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46503092
156p53 signaling pathway_Homo sapiens_hsa041150.43608410
157Folate biosynthesis_Homo sapiens_hsa007900.43093411
158Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.42769867
159Oocyte meiosis_Homo sapiens_hsa041140.42165414
160Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42073170
161Histidine metabolism_Homo sapiens_hsa003400.39255213
162mRNA surveillance pathway_Homo sapiens_hsa030150.38005373
163Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.35501691
164SNARE interactions in vesicular transport_Homo sapiens_hsa041300.32894370
165Phenylalanine metabolism_Homo sapiens_hsa003600.32237408
166Glutamatergic synapse_Homo sapiens_hsa047240.31342375
167Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30982751
168Amphetamine addiction_Homo sapiens_hsa050310.30593865
169Alcoholism_Homo sapiens_hsa050340.27487297
170Drug metabolism - other enzymes_Homo sapiens_hsa009830.25990964
171Taste transduction_Homo sapiens_hsa047420.25564685
172Autoimmune thyroid disease_Homo sapiens_hsa053200.25463554
173Rheumatoid arthritis_Homo sapiens_hsa053230.24712864
174Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.23410978
175GABAergic synapse_Homo sapiens_hsa047270.20358494
176Chemical carcinogenesis_Homo sapiens_hsa052040.20332423
177Morphine addiction_Homo sapiens_hsa050320.19892548
178Hedgehog signaling pathway_Homo sapiens_hsa043400.19853721
179Cocaine addiction_Homo sapiens_hsa050300.18282211
180Pyruvate metabolism_Homo sapiens_hsa006200.18146084
181Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.17323432
182Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.17232955
183Peroxisome_Homo sapiens_hsa041460.16950155
184Butanoate metabolism_Homo sapiens_hsa006500.16631158
185Retinol metabolism_Homo sapiens_hsa008300.16452155
186Long-term depression_Homo sapiens_hsa047300.13530311
187Glycerophospholipid metabolism_Homo sapiens_hsa005640.12751549
188Gap junction_Homo sapiens_hsa045400.12108205
189Steroid hormone biosynthesis_Homo sapiens_hsa001400.09359248
190Phagosome_Homo sapiens_hsa041450.07187909
191Sulfur metabolism_Homo sapiens_hsa009200.07015230
192Wnt signaling pathway_Homo sapiens_hsa043100.06002209
193Calcium signaling pathway_Homo sapiens_hsa040200.05734673
194Asthma_Homo sapiens_hsa053100.05026407
195beta-Alanine metabolism_Homo sapiens_hsa004100.02750826

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