KATNAL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)8.24732629
2motile cilium assembly (GO:0044458)7.42449354
3epithelial cilium movement (GO:0003351)7.29066386
4piRNA metabolic process (GO:0034587)7.26392287
5cilium movement (GO:0003341)7.15960801
6sperm motility (GO:0030317)6.84771604
7acrosome reaction (GO:0007340)6.64268808
8multicellular organism reproduction (GO:0032504)6.48158329
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.31484711
10fusion of sperm to egg plasma membrane (GO:0007342)6.25781270
11regulation of cilium movement (GO:0003352)6.23593182
12sperm-egg recognition (GO:0035036)6.20406524
13male meiosis (GO:0007140)5.94851603
14acrosome assembly (GO:0001675)5.85375684
15binding of sperm to zona pellucida (GO:0007339)5.80088981
16spermatid development (GO:0007286)5.44305175
17protein localization to cilium (GO:0061512)5.36908453
18cell-cell recognition (GO:0009988)5.35465067
19DNA methylation involved in gamete generation (GO:0043046)5.00667720
20plasma membrane fusion (GO:0045026)4.85298458
21axoneme assembly (GO:0035082)4.83848652
22reproduction (GO:0000003)4.83838563
23synaptonemal complex organization (GO:0070193)4.75381830
24cell wall macromolecule metabolic process (GO:0044036)4.72169663
25cell wall macromolecule catabolic process (GO:0016998)4.72169663
26single fertilization (GO:0007338)4.71879899
27intraciliary transport (GO:0042073)4.70494538
28microtubule depolymerization (GO:0007019)4.44228203
29synaptonemal complex assembly (GO:0007130)4.39072253
30detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)4.36541490
31cilium organization (GO:0044782)4.23043835
32cilium assembly (GO:0042384)4.20092498
33ventricular system development (GO:0021591)4.16863609
34fertilization (GO:0009566)4.12296070
35male meiosis I (GO:0007141)4.02318491
36sperm capacitation (GO:0048240)3.97241430
37indolalkylamine metabolic process (GO:0006586)3.89993697
38indole-containing compound catabolic process (GO:0042436)3.81108110
39indolalkylamine catabolic process (GO:0046218)3.81108110
40tryptophan catabolic process (GO:0006569)3.81108110
41neural tube formation (GO:0001841)3.66494839
42spermatogenesis (GO:0007283)3.65792256
43male gamete generation (GO:0048232)3.65486274
44chromosome organization involved in meiosis (GO:0070192)3.65396024
45cilium morphogenesis (GO:0060271)3.64239481
46kynurenine metabolic process (GO:0070189)3.60238805
47meiotic cell cycle (GO:0051321)3.58410840
48regulation of microtubule-based movement (GO:0060632)3.56152395
49meiotic nuclear division (GO:0007126)3.51636289
50germ cell development (GO:0007281)3.51178289
51calcium ion-dependent exocytosis (GO:0017156)3.48043502
52regulation of sarcomere organization (GO:0060297)3.46988672
53single strand break repair (GO:0000012)3.45667469
54gamete generation (GO:0007276)3.45472025
55negative regulation of cytosolic calcium ion concentration (GO:0051481)3.45359829
56centriole assembly (GO:0098534)3.44158079
57cellular component assembly involved in morphogenesis (GO:0010927)3.37175999
58tryptophan metabolic process (GO:0006568)3.32618586
59response to pheromone (GO:0019236)3.31950323
60signal peptide processing (GO:0006465)3.27831524
61cellular process involved in reproduction in multicellular organism (GO:0022412)3.25359787
62protein polyglutamylation (GO:0018095)3.24380206
63left/right pattern formation (GO:0060972)3.24255833
64nonmotile primary cilium assembly (GO:0035058)3.23155128
65photoreceptor cell maintenance (GO:0045494)3.22554838
66cell recognition (GO:0008037)3.14362734
67meiosis I (GO:0007127)3.13483995
68centriole replication (GO:0007099)3.11347588
69regulation of centriole replication (GO:0046599)3.06607196
70auditory receptor cell stereocilium organization (GO:0060088)3.05039970
71G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.02085181
72behavioral response to nicotine (GO:0035095)3.00628068
73cellular ketone body metabolic process (GO:0046950)2.99124454
74positive regulation of developmental pigmentation (GO:0048087)2.98340993
75thyroid hormone metabolic process (GO:0042403)2.97937894
76* microtubule severing (GO:0051013)2.97202244
77synapsis (GO:0007129)2.97032450
78cornea development in camera-type eye (GO:0061303)2.96203078
79indole-containing compound metabolic process (GO:0042430)2.95884171
80serotonin metabolic process (GO:0042428)2.95171812
81GTP biosynthetic process (GO:0006183)2.93985068
82retinal cone cell development (GO:0046549)2.93484350
83snRNA transcription (GO:0009301)2.93468192
84left/right axis specification (GO:0070986)2.93273989
85reflex (GO:0060004)2.92887666
86brain morphogenesis (GO:0048854)2.91714953
87gamma-aminobutyric acid transport (GO:0015812)2.91196598
88regulation of rhodopsin mediated signaling pathway (GO:0022400)2.91042779
89L-fucose catabolic process (GO:0042355)2.90556395
90fucose catabolic process (GO:0019317)2.90556395
91L-fucose metabolic process (GO:0042354)2.90556395
92negative regulation of inclusion body assembly (GO:0090084)2.89499800
93regulation of meiosis I (GO:0060631)2.89311176
94detection of mechanical stimulus involved in sensory perception (GO:0050974)2.88939701
95cellular response to sterol (GO:0036315)2.86737531
96L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.84756976
97inner ear receptor stereocilium organization (GO:0060122)2.83902532
98regulation of inclusion body assembly (GO:0090083)2.83677356
99behavioral response to ethanol (GO:0048149)2.82071609
100monoubiquitinated protein deubiquitination (GO:0035520)2.80695284
101regulation of hippo signaling (GO:0035330)2.79705719
102establishment of protein localization to Golgi (GO:0072600)2.79300811
103prenylation (GO:0097354)2.79039902
104protein prenylation (GO:0018342)2.79039902
105microtubule-based movement (GO:0007018)2.75337756
106benzene-containing compound metabolic process (GO:0042537)2.75049125
107primary amino compound metabolic process (GO:1901160)2.74685466
108rhodopsin mediated signaling pathway (GO:0016056)2.74047149
109photoreceptor cell development (GO:0042461)2.73778435
110nucleoside diphosphate phosphorylation (GO:0006165)2.72649734
111regulation of collateral sprouting (GO:0048670)2.70614444
112interkinetic nuclear migration (GO:0022027)2.70049223
113amino acid salvage (GO:0043102)2.69693958
114L-methionine salvage (GO:0071267)2.69693958
115L-methionine biosynthetic process (GO:0071265)2.69693958
116histone H2A acetylation (GO:0043968)2.69554259
117resolution of meiotic recombination intermediates (GO:0000712)2.68844965
118regulation of pigment cell differentiation (GO:0050932)2.67379707
119response to nitrosative stress (GO:0051409)2.67333167
120eye photoreceptor cell development (GO:0042462)2.67285293
121replicative senescence (GO:0090399)2.67170735
122ketone body metabolic process (GO:1902224)2.66277590
123presynaptic membrane assembly (GO:0097105)2.65336423
124C4-dicarboxylate transport (GO:0015740)2.64542384
125tachykinin receptor signaling pathway (GO:0007217)2.64014448
126multicellular organismal reproductive process (GO:0048609)2.63466199
127NAD biosynthetic process (GO:0009435)2.61261440
128meiotic cell cycle process (GO:1903046)2.59806720
129regulation of gene silencing by RNA (GO:0060966)2.58652620
130regulation of posttranscriptional gene silencing (GO:0060147)2.58652620
131regulation of gene silencing by miRNA (GO:0060964)2.58652620
132microtubule polymerization or depolymerization (GO:0031109)2.56724033
133regulation of translation, ncRNA-mediated (GO:0045974)2.55631161
134negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.55631161
135negative regulation of translation, ncRNA-mediated (GO:0040033)2.55631161
136detection of light stimulus involved in visual perception (GO:0050908)2.55516280
137detection of light stimulus involved in sensory perception (GO:0050962)2.55516280
138microtubule anchoring (GO:0034453)2.55079289
139neuronal action potential (GO:0019228)2.54706923
140positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.54220257
141righting reflex (GO:0060013)2.54031612
142cellular biogenic amine catabolic process (GO:0042402)2.52635134
143amine catabolic process (GO:0009310)2.52635134
144cell projection assembly (GO:0030031)2.51963766
145startle response (GO:0001964)2.50344672
146positive regulation of male gonad development (GO:2000020)2.50341853
147negative regulation of systemic arterial blood pressure (GO:0003085)2.49934712
148positive regulation of oligodendrocyte differentiation (GO:0048714)2.49387246
149protein K6-linked ubiquitination (GO:0085020)2.49298159
150replication fork processing (GO:0031297)2.49143967
151protein localization to chromosome, centromeric region (GO:0071459)2.47262343
152smoothened signaling pathway (GO:0007224)2.45918265
153organic cation transport (GO:0015695)2.45472532
154microtubule bundle formation (GO:0001578)2.45258752
155preassembly of GPI anchor in ER membrane (GO:0016254)2.45203784
156histone exchange (GO:0043486)2.44040362
157limb development (GO:0060173)2.43763258
158appendage development (GO:0048736)2.43763258
159regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.42856401
160female gonad development (GO:0008585)2.41213309
161determination of left/right symmetry (GO:0007368)2.40712286
162guanosine-containing compound biosynthetic process (GO:1901070)2.40038004
163urinary tract smooth muscle contraction (GO:0014848)2.40027850
164retinal rod cell development (GO:0046548)2.39979369
165regulation of male gonad development (GO:2000018)2.39051605
166spermatid nucleus differentiation (GO:0007289)2.38024483
167neuron cell-cell adhesion (GO:0007158)2.37345237
168cilium or flagellum-dependent cell motility (GO:0001539)10.0312101

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.45221171
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.02991841
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.44329160
4GBX2_23144817_ChIP-Seq_PC3_Human2.86513734
5CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.55404973
6FLI1_27457419_Chip-Seq_LIVER_Mouse2.47365247
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.44903198
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.43314307
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.34531474
10PCGF2_27294783_Chip-Seq_ESCs_Mouse2.31129065
11CBX2_27304074_Chip-Seq_ESCs_Mouse2.28136556
12VDR_22108803_ChIP-Seq_LS180_Human2.10524592
13PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.10450083
14PIAS1_25552417_ChIP-Seq_VCAP_Human2.07206297
15RNF2_27304074_Chip-Seq_NSC_Mouse1.98659583
16CTBP2_25329375_ChIP-Seq_LNCAP_Human1.96968114
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.94944149
18BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.93092303
19FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.90089073
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.89519012
21FUS_26573619_Chip-Seq_HEK293_Human1.88267357
22BMI1_23680149_ChIP-Seq_NPCS_Mouse1.88002774
23POU3F2_20337985_ChIP-ChIP_501MEL_Human1.83162630
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.78566578
25SUZ12_27294783_Chip-Seq_NPCs_Mouse1.75084398
26* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.74170478
27TAF15_26573619_Chip-Seq_HEK293_Human1.73827144
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.72507551
29TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.70749705
30NFE2_27457419_Chip-Seq_LIVER_Mouse1.66993046
31AR_21572438_ChIP-Seq_LNCaP_Human1.65132535
32RBPJ_22232070_ChIP-Seq_NCS_Mouse1.63080903
33NANOG_18555785_Chip-Seq_ESCs_Mouse1.62294963
34BCAT_22108803_ChIP-Seq_LS180_Human1.60635586
35REST_21632747_ChIP-Seq_MESCs_Mouse1.59835878
36EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.57698149
37PCGF2_27294783_Chip-Seq_NPCs_Mouse1.55531044
38AR_25329375_ChIP-Seq_VCAP_Human1.53492356
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.53370402
40RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51948239
41SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.46852222
42TAL1_26923725_Chip-Seq_HPCs_Mouse1.44631692
43KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.44065127
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42373832
45P53_22387025_ChIP-Seq_ESCs_Mouse1.42084021
46ER_23166858_ChIP-Seq_MCF-7_Human1.42020391
47CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41399453
48E2F1_18555785_Chip-Seq_ESCs_Mouse1.41325123
49MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.40965826
50TCF4_22108803_ChIP-Seq_LS180_Human1.40707043
51OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40429089
52KLF5_20875108_ChIP-Seq_MESCs_Mouse1.39982370
53STAT3_18555785_Chip-Seq_ESCs_Mouse1.39882041
54EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.39790183
55P300_19829295_ChIP-Seq_ESCs_Human1.39460880
56EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.39310945
57RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.38835847
58GATA1_26923725_Chip-Seq_HPCs_Mouse1.38183799
59SMAD4_21799915_ChIP-Seq_A2780_Human1.37601658
60SUZ12_18555785_Chip-Seq_ESCs_Mouse1.37472757
61* RUNX2_22187159_ChIP-Seq_PCA_Human1.36733093
62EZH2_27294783_Chip-Seq_NPCs_Mouse1.36637780
63POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.35039240
64TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35039240
65CMYC_18555785_Chip-Seq_ESCs_Mouse1.32885030
66TP53_16413492_ChIP-PET_HCT116_Human1.31575024
67OCT4_18555785_Chip-Seq_ESCs_Mouse1.31208769
68P300_18555785_Chip-Seq_ESCs_Mouse1.31069587
69E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.29804320
70FLI1_21867929_ChIP-Seq_TH2_Mouse1.29295345
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.27404704
72EZH2_27304074_Chip-Seq_ESCs_Mouse1.27031582
73SMAD3_21741376_ChIP-Seq_EPCs_Human1.26416522
74KDM2B_26808549_Chip-Seq_REH_Human1.26219891
75SOX2_18555785_Chip-Seq_ESCs_Mouse1.25407962
76NMYC_18555785_Chip-Seq_ESCs_Mouse1.24941919
77ELK4_26923725_Chip-Seq_MESODERM_Mouse1.24646684
78CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.22642287
79NANOG_19829295_ChIP-Seq_ESCs_Human1.21948811
80SOX2_19829295_ChIP-Seq_ESCs_Human1.21948811
81KAP1_22055183_ChIP-Seq_ESCs_Mouse1.21826798
82SMAD4_21741376_ChIP-Seq_EPCs_Human1.20724072
83KLF4_18555785_Chip-Seq_ESCs_Mouse1.20374994
84ZFX_18555785_Chip-Seq_ESCs_Mouse1.17978304
85AHR_22903824_ChIP-Seq_MCF-7_Human1.17901313
86ZNF274_21170338_ChIP-Seq_K562_Hela1.17354307
87* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.17284852
88CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.16620435
89TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16620340
90PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.16324775
91PRDM14_20953172_ChIP-Seq_ESCs_Human1.16106481
92DROSHA_22980978_ChIP-Seq_HELA_Human1.15669462
93FOXM1_26456572_ChIP-Seq_MCF-7_Human1.15211746
94RUNX1_27457419_Chip-Seq_LIVER_Mouse1.15007085
95SOX2_21211035_ChIP-Seq_LN229_Gbm1.13308371
96ARNT_22903824_ChIP-Seq_MCF-7_Human1.12713665
97UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12198494
98TP53_22573176_ChIP-Seq_HFKS_Human1.11804521
99ESRRB_18555785_Chip-Seq_ESCs_Mouse1.11720707
100SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.11526058
101SOX9_26525672_Chip-Seq_HEART_Mouse1.11441022
102EED_16625203_ChIP-ChIP_MESCs_Mouse1.11220476
103RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.10608717
104EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10308237
105CTCF_18555785_Chip-Seq_ESCs_Mouse1.08895270
106CRX_20693478_ChIP-Seq_RETINA_Mouse1.08744024
107TCF4_23295773_ChIP-Seq_U87_Human1.08083368
108TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08053158
109PU1_27457419_Chip-Seq_LIVER_Mouse1.07290360
110TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07186212
111GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06868430
112EWS_26573619_Chip-Seq_HEK293_Human1.06139933
113CDX2_19796622_ChIP-Seq_MESCs_Mouse1.05441060
114STAT3_23295773_ChIP-Seq_U87_Human1.05427314
115IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.04345401
116CBP_20019798_ChIP-Seq_JUKART_Human1.04345401
117POU5F1_16153702_ChIP-ChIP_HESCs_Human1.04131836
118EZH2_27294783_Chip-Seq_ESCs_Mouse1.03855644
119FOXA1_21572438_ChIP-Seq_LNCaP_Human1.03391170
120TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.03308458
121SMAD3_21741376_ChIP-Seq_ESCs_Human1.03281901
122RNF2_27304074_Chip-Seq_ESCs_Mouse1.02803902
123CDX2_22108803_ChIP-Seq_LS180_Human1.02715259
124SMAD3_21741376_ChIP-Seq_HESCs_Human1.02407159
125SMAD1_18555785_Chip-Seq_ESCs_Mouse1.02324677
126STAT1_17558387_ChIP-Seq_HELA_Human1.02075551
127IGF1R_20145208_ChIP-Seq_DFB_Human1.00389146
128CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.00357464
129FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00239627
130FOXA1_25329375_ChIP-Seq_VCAP_Human1.00239627
131SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.00014016
132SALL1_21062744_ChIP-ChIP_HESCs_Human0.99766444
133WDR5_24793694_ChIP-Seq_LNCAP_Human0.99749774
134CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.98088998
135AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97615768
136OCT4_21477851_ChIP-Seq_ESCs_Mouse0.97551702
137TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97277247

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization6.14482248
2MP0008877_abnormal_DNA_methylation3.83708407
3MP0000569_abnormal_digit_pigmentation3.06667843
4MP0003698_abnormal_male_reproductive2.94427578
5MP0005423_abnormal_somatic_nervous2.91168767
6MP0001929_abnormal_gametogenesis2.69442324
7MP0006292_abnormal_olfactory_placode2.68414218
8MP0002638_abnormal_pupillary_reflex2.53051399
9MP0001984_abnormal_olfaction2.51014085
10MP0003195_calcinosis2.48311872
11MP0003787_abnormal_imprinting2.43837099
12MP0005551_abnormal_eye_electrophysiolog2.43478632
13MP0001188_hyperpigmentation2.42271785
14MP0002102_abnormal_ear_morphology2.26549300
15MP0005646_abnormal_pituitary_gland2.20330568
16MP0002210_abnormal_sex_determination2.14257846
17MP0003880_abnormal_central_pattern2.13225230
18MP0008057_abnormal_DNA_replication2.12325184
19MP0000383_abnormal_hair_follicle2.07244464
20MP0005253_abnormal_eye_physiology1.97997745
21MP0001986_abnormal_taste_sensitivity1.92740505
22MP0002653_abnormal_ependyma_morphology1.87064001
23MP0003136_yellow_coat_color1.84521281
24MP0006072_abnormal_retinal_apoptosis1.77292020
25MP0004043_abnormal_pH_regulation1.74922019
26MP0001529_abnormal_vocalization1.73070509
27MP0008058_abnormal_DNA_repair1.73011680
28MP0003011_delayed_dark_adaptation1.68909103
29MP0009046_muscle_twitch1.67679305
30MP0003121_genomic_imprinting1.65821743
31MP0002161_abnormal_fertility/fecundity1.61559826
32MP0000427_abnormal_hair_cycle1.60311782
33MP0005645_abnormal_hypothalamus_physiol1.59351913
34MP0001145_abnormal_male_reproductive1.57758507
35MP0004133_heterotaxia1.54660756
36MP0000653_abnormal_sex_gland1.52901036
37MP0002160_abnormal_reproductive_system1.51185182
38MP0002837_dystrophic_cardiac_calcinosis1.49244470
39MP0003646_muscle_fatigue1.48784195
40MP0000566_synostosis1.48497931
41MP0000372_irregular_coat_pigmentation1.45787818
42MP0001486_abnormal_startle_reflex1.44760432
43MP0004270_analgesia1.44557168
44MP0010386_abnormal_urinary_bladder1.43390558
45MP0002736_abnormal_nociception_after1.43241886
46MP0001502_abnormal_circadian_rhythm1.41666815
47MP0004147_increased_porphyrin_level1.38183359
48MP0002572_abnormal_emotion/affect_behav1.35317997
49MP0000778_abnormal_nervous_system1.35082258
50MP0004885_abnormal_endolymph1.32164389
51MP0008872_abnormal_physiological_respon1.31773815
52MP0008789_abnormal_olfactory_epithelium1.29238577
53MP0006276_abnormal_autonomic_nervous1.28780213
54MP0003122_maternal_imprinting1.28434723
55MP0001968_abnormal_touch/_nociception1.28254548
56MP0000631_abnormal_neuroendocrine_gland1.26300629
57MP0005174_abnormal_tail_pigmentation1.24908054
58MP0005171_absent_coat_pigmentation1.21931372
59MP0003950_abnormal_plasma_membrane1.21174549
60MP0001905_abnormal_dopamine_level1.20897005
61MP0005670_abnormal_white_adipose1.19649329
62MP0004142_abnormal_muscle_tone1.19321463
63MP0003123_paternal_imprinting1.19160964
64MP0002734_abnormal_mechanical_nocicepti1.18683103
65MP0009745_abnormal_behavioral_response1.17817318
66MP0000049_abnormal_middle_ear1.17716976
67MP0005187_abnormal_penis_morphology1.17695470
68MP0005394_taste/olfaction_phenotype1.17634987
69MP0005499_abnormal_olfactory_system1.17634987
70MP0010094_abnormal_chromosome_stability1.17279545
71MP0001970_abnormal_pain_threshold1.15663048
72MP0002557_abnormal_social/conspecific_i1.13845101
73MP0003890_abnormal_embryonic-extraembry1.12642162
74MP0002063_abnormal_learning/memory/cond1.10997386
75MP0003635_abnormal_synaptic_transmissio1.10341665
76MP0004215_abnormal_myocardial_fiber1.07905784
77MP0002272_abnormal_nervous_system1.06262890
78MP0008875_abnormal_xenobiotic_pharmacok1.04992121
79MP0003937_abnormal_limbs/digits/tail_de1.03731982
80MP0005391_vision/eye_phenotype1.03324688
81MP0002752_abnormal_somatic_nervous1.03211370
82MP0004742_abnormal_vestibular_system1.03050424
83MP0000026_abnormal_inner_ear1.02686875
84MP0010678_abnormal_skin_adnexa1.01941715
85MP0008995_early_reproductive_senescence1.01339747
86MP0005377_hearing/vestibular/ear_phenot1.01334428
87MP0003878_abnormal_ear_physiology1.01334428
88MP0002067_abnormal_sensory_capabilities0.99582191
89MP0009697_abnormal_copulation0.99545587
90MP0005503_abnormal_tendon_morphology0.98273219
91MP0005195_abnormal_posterior_eye0.96438123
92MP0004085_abnormal_heartbeat0.96262221
93MP0003786_premature_aging0.96205822
94MP0005409_darkened_coat_color0.95842878
95MP0002064_seizures0.95513022
96MP0002733_abnormal_thermal_nociception0.95491823
97MP0001440_abnormal_grooming_behavior0.95063964
98MP0004145_abnormal_muscle_electrophysio0.94495865
99MP0005085_abnormal_gallbladder_physiolo0.94448909
100MP0002184_abnormal_innervation0.93600198
101MP0005389_reproductive_system_phenotype0.92449968
102MP0000538_abnormal_urinary_bladder0.91842067
103MP0002928_abnormal_bile_duct0.88872932
104MP0005220_abnormal_exocrine_pancreas0.88357478
105MP0002229_neurodegeneration0.87810735
106MP0008007_abnormal_cellular_replicative0.87241799
107MP0003315_abnormal_perineum_morphology0.86767603
108MP0001963_abnormal_hearing_physiology0.85207483
109MP0002168_other_aberrant_phenotype0.84991148
110MP0009250_abnormal_appendicular_skeleto0.84960098
111MP0004134_abnormal_chest_morphology0.84867324
112MP0002882_abnormal_neuron_morphology0.83790856
113MP0002234_abnormal_pharynx_morphology0.82683415
114MP0001485_abnormal_pinna_reflex0.82635841
115MP0003137_abnormal_impulse_conducting0.81881804
116MP0001501_abnormal_sleep_pattern0.80932964
117MP0005075_abnormal_melanosome_morpholog0.80304241
118MP0002751_abnormal_autonomic_nervous0.79742977
119MP0001324_abnormal_eye_pigmentation0.78687060
120MP0002090_abnormal_vision0.78644196
121MP0001119_abnormal_female_reproductive0.77754971
122MP0002735_abnormal_chemical_nociception0.76829289
123MP0002876_abnormal_thyroid_physiology0.76222748
124MP0004924_abnormal_behavior0.76111864
125MP0005386_behavior/neurological_phenoty0.76111864
126MP0002282_abnormal_trachea_morphology0.75541422
127MP0003861_abnormal_nervous_system0.74901617
128MP0003111_abnormal_nucleus_morphology0.74551281
129MP0002163_abnormal_gland_morphology0.74422919
130MP0002152_abnormal_brain_morphology0.73814341
131MP0002277_abnormal_respiratory_mucosa0.73756941
132MP0002938_white_spotting0.72870503
133MP0002233_abnormal_nose_morphology0.72812634
134MP0003718_maternal_effect0.71081580

Predicted human phenotypes

RankGene SetZ-score
1Respiratory insufficiency due to defective ciliary clearance (HP:0200073)8.97868138
2Absent/shortened dynein arms (HP:0200106)7.70580570
3Dynein arm defect of respiratory motile cilia (HP:0012255)7.70580570
4Abnormal respiratory motile cilium physiology (HP:0012261)7.10176358
5Abnormal respiratory motile cilium morphology (HP:0005938)6.49426059
6Abnormal respiratory epithelium morphology (HP:0012253)6.49426059
7Abnormal ciliary motility (HP:0012262)6.33463878
8Rhinitis (HP:0012384)5.75545761
9Chronic bronchitis (HP:0004469)4.30691370
10Medial flaring of the eyebrow (HP:0010747)4.29215745
11Nephronophthisis (HP:0000090)4.05759230
12Congenital primary aphakia (HP:0007707)3.67682724
13Gait imbalance (HP:0002141)3.65363537
14Infertility (HP:0000789)3.64017539
15True hermaphroditism (HP:0010459)3.52887323
16Congenital stationary night blindness (HP:0007642)3.37709999
17Nephrogenic diabetes insipidus (HP:0009806)3.33696521
18Abnormality of the renal medulla (HP:0100957)3.30707244
19Pancreatic fibrosis (HP:0100732)3.29446016
20Chronic hepatic failure (HP:0100626)3.26228148
21Hyperventilation (HP:0002883)3.21707669
22Bronchiectasis (HP:0002110)3.12734961
23Gaze-evoked nystagmus (HP:0000640)2.92700863
24Tubulointerstitial nephritis (HP:0001970)2.83834581
25Molar tooth sign on MRI (HP:0002419)2.81626779
26Abnormality of midbrain morphology (HP:0002418)2.81626779
27Fibular hypoplasia (HP:0003038)2.78074520
28Progressive cerebellar ataxia (HP:0002073)2.76910422
29Genital tract atresia (HP:0001827)2.74601809
30Vaginal atresia (HP:0000148)2.69809233
31Aplasia/Hypoplasia of the lens (HP:0008063)2.68738698
32Pancreatic cysts (HP:0001737)2.68029224
33Genetic anticipation (HP:0003743)2.62981825
34Postaxial foot polydactyly (HP:0001830)2.62808345
35Poor coordination (HP:0002370)2.61786979
36Median cleft lip (HP:0000161)2.60738533
37Bony spicule pigmentary retinopathy (HP:0007737)2.46078404
38Supernumerary spleens (HP:0009799)2.43170720
39Central scotoma (HP:0000603)2.39291544
40Aplasia/Hypoplasia of the fibula (HP:0006492)2.34085658
41Postaxial hand polydactyly (HP:0001162)2.32022401
42Occipital encephalocele (HP:0002085)2.29201504
43Congenital hepatic fibrosis (HP:0002612)2.25828638
44Polydipsia (HP:0001959)2.25469896
45Abnormal drinking behavior (HP:0030082)2.25469896
46Chromosomal breakage induced by crosslinking agents (HP:0003221)2.24446467
47Broad-based gait (HP:0002136)2.23673018
48Absent speech (HP:0001344)2.21520738
49Preaxial hand polydactyly (HP:0001177)2.20565818
50Hypoplasia of the capital femoral epiphysis (HP:0003090)2.19364936
51Decreased central vision (HP:0007663)2.18283645
52Furrowed tongue (HP:0000221)2.17525993
53Aplasia/Hypoplasia of the tongue (HP:0010295)2.16679457
54Abolished electroretinogram (ERG) (HP:0000550)2.14726440
55Abnormal rod and cone electroretinograms (HP:0008323)2.11744711
56Decreased circulating renin level (HP:0003351)2.11109048
57Focal motor seizures (HP:0011153)2.10923852
58Cerebellar dysplasia (HP:0007033)2.10866407
59Type II lissencephaly (HP:0007260)2.08843409
60Renal cortical cysts (HP:0000803)2.08515805
61Protruding tongue (HP:0010808)2.07562189
62Cystic liver disease (HP:0006706)2.06767386
63Facial cleft (HP:0002006)2.05309847
64Abnormality of the dental root (HP:0006486)2.03861702
65Taurodontia (HP:0000679)2.03861702
66Abnormality of permanent molar morphology (HP:0011071)2.03861702
67Short foot (HP:0001773)2.03408289
68Attenuation of retinal blood vessels (HP:0007843)2.01958473
69Chromsome breakage (HP:0040012)2.01204293
70Astigmatism (HP:0000483)1.97018052
71Focal seizures (HP:0007359)1.95588413
72Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.95358262
73Absent epiphyses (HP:0010577)1.95358262
74Abnormal biliary tract physiology (HP:0012439)1.94999675
75Bile duct proliferation (HP:0001408)1.94999675
76Abnormality of molar morphology (HP:0011070)1.94061464
77Abnormality of molar (HP:0011077)1.94061464
78Intestinal atresia (HP:0011100)1.94054448
79Pendular nystagmus (HP:0012043)1.92666586
8011 pairs of ribs (HP:0000878)1.92026954
81Retinitis pigmentosa (HP:0000510)1.89987458
82Polyuria (HP:0000103)1.89855329
83Abnormality of the dental pulp (HP:0006479)1.88832893
84Tubulointerstitial abnormality (HP:0001969)1.87916916
85Recurrent sinusitis (HP:0011108)1.87107795
86Bronchitis (HP:0012387)1.87006874
87Broad foot (HP:0001769)1.86973013
88Nasal polyposis (HP:0100582)1.85997596
89Hip dysplasia (HP:0001385)1.84015408
90Prominent nasal bridge (HP:0000426)1.83909850
91Severe visual impairment (HP:0001141)1.83765473
92Dialeptic seizures (HP:0011146)1.81520824
93Keratoconus (HP:0000563)1.79952616
94Increased corneal curvature (HP:0100692)1.79952616
95Chronic sinusitis (HP:0011109)1.78681140
96Abdominal situs inversus (HP:0003363)1.78397158
97Abnormality of abdominal situs (HP:0011620)1.78397158
98Gonadotropin excess (HP:0000837)1.78199806
99Sclerocornea (HP:0000647)1.78026391
100Abnormality of macular pigmentation (HP:0008002)1.78014747
101Dandy-Walker malformation (HP:0001305)1.77238967
102Male pseudohermaphroditism (HP:0000037)1.76477273
103Optic disc pallor (HP:0000543)1.75301891
104Optic nerve hypoplasia (HP:0000609)1.74661857
105Narrow forehead (HP:0000341)1.74379451
106Acute necrotizing encephalopathy (HP:0006965)1.74029969
107Anencephaly (HP:0002323)1.73833120
108Aganglionic megacolon (HP:0002251)1.73778109
109Hemiparesis (HP:0001269)1.73003634
110Renal dysplasia (HP:0000110)1.72700586
111Tubular atrophy (HP:0000092)1.72597411
112Recurrent otitis media (HP:0000403)1.72323763
113Epileptic encephalopathy (HP:0200134)1.70595531
114Stage 5 chronic kidney disease (HP:0003774)1.69459235
115Aplasia/Hypoplasia of the tibia (HP:0005772)1.68973852
116Absent rod-and cone-mediated responses on ERG (HP:0007688)1.68694375
117Sloping forehead (HP:0000340)1.68266428
118Enlarged kidneys (HP:0000105)1.67323438
119Multicystic kidney dysplasia (HP:0000003)1.67106390
120Congenital sensorineural hearing impairment (HP:0008527)1.66856525
121Clumsiness (HP:0002312)1.66705953
122Abnormality of the renal cortex (HP:0011035)1.66403280
123Aplasia/Hypoplasia of the fovea (HP:0008060)1.66047787
124Hypoplasia of the fovea (HP:0007750)1.66047787
125Colon cancer (HP:0003003)1.65587054
126Nephroblastoma (Wilms tumor) (HP:0002667)1.64955038
127Specific learning disability (HP:0001328)1.64186127
128Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.64068220
129Abnormality of alanine metabolism (HP:0010916)1.64068220
130Hyperalaninemia (HP:0003348)1.64068220
131Dyschromatopsia (HP:0007641)1.63378876
132Bell-shaped thorax (HP:0001591)1.61918332
133Dental crowding (HP:0000678)1.61469249
134Oculomotor apraxia (HP:0000657)1.61269795
135Left ventricular hypertrophy (HP:0001712)1.60250914
136Febrile seizures (HP:0002373)1.59966723
137Abnormal mitochondria in muscle tissue (HP:0008316)1.59825553
138Fibular aplasia (HP:0002990)1.59041018
139Abnormality of the fovea (HP:0000493)1.56603273
140Male infertility (HP:0003251)1.55605501
141Thyroid-stimulating hormone excess (HP:0002925)1.54863332
142Bifid tongue (HP:0010297)1.54663819
143Choroideremia (HP:0001139)1.53672826
144Embryonal renal neoplasm (HP:0011794)1.52379908

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK7.46977911
2PDK34.97111959
3PDK44.97111959
4CASK3.45335474
5PRKD33.32269578
6PDK23.20849670
7MAP4K23.02559100
8TNIK2.38599292
9STK162.30355296
10PLK42.25830159
11CCNB12.17643820
12NUAK12.16777230
13MKNK22.14340238
14PNCK2.10698625
15ACVR1B2.10564105
16TAOK32.09011551
17TESK12.07804205
18MAP2K71.78482840
19MAPK131.75181968
20BMPR21.74060964
21BMPR1B1.70065071
22MUSK1.65777324
23NTRK21.59875867
24NTRK31.55622597
25PBK1.55183555
26MKNK11.54336327
27PIK3CG1.44263982
28SRPK11.43045363
29CDK31.39879917
30STK38L1.37219636
31OXSR11.34451475
32TTK1.33120460
33ICK1.23710895
34MARK11.23339690
35AKT31.22863353
36NEK61.21939279
37BRAF1.15575345
38ERBB31.13010334
39PLK21.09075980
40PTK2B1.08068208
41STK391.06420365
42CDC71.01291662
43TLK11.00895648
44TRIM281.00606070
45IRAK20.99561773
46NLK0.98692141
47WNK40.98687570
48TIE10.97855000
49FER0.96993576
50ZAK0.96490415
51MAP3K120.95711155
52DYRK30.94179182
53SGK20.94144243
54LATS10.92824225
55TEC0.92029734
56YES10.90683605
57CHEK20.88243562
58NEK20.87750184
59DAPK20.86306757
60PLK30.85178365
61MAP3K40.82762778
62CSNK1A1L0.81745128
63PRPF4B0.78413561
64IRAK10.77784201
65PRKCG0.77362948
66EIF2AK20.76370762
67PLK10.75288087
68ATR0.75206795
69SGK4940.74875728
70SGK2230.74875728
71CSNK1G20.74821422
72CSNK1G10.74690671
73PAK30.74139825
74STK380.72222411
75DYRK1A0.72159700
76GRK10.68181660
77BRSK20.67910258
78TGFBR10.66736417
79WEE10.66026147
80MST40.65759076
81CAMK2A0.65507307
82OBSCN0.64987999
83TAF10.63930426
84PRKAA20.60891992
85BCR0.60323333
86PIK3CA0.59590683
87CAMK10.57776355
88CSNK1G30.56909854
89CDK190.56659517
90TSSK60.56499444
91FGFR20.55852111
92PINK10.55806291
93EPHA30.54744273
94PKN10.54293288
95CDK80.54052441
96CAMK40.53723777
97CAMK1G0.53366761
98ATM0.53285114
99PHKG20.53012402
100PHKG10.53012402
101TXK0.50803589
102ADRBK20.50478510
103CAMKK20.50416379
104STK40.50262719
105BCKDK0.49986035
106CHEK10.49863166
107MAPK150.49771951
108BUB10.49714735
109PRKAA10.48731611
110DYRK20.48720388
111SIK30.47151294
112PRKACB0.46928528
113ADRBK10.45790293
114CAMK1D0.45083454
115WNK30.44235204
116STK110.43189028
117MAPKAPK50.42519869
118CSNK1A10.40202779
119RPS6KB10.39007641
120EPHA40.38454391
121STK30.37233863
122PRKCQ0.36907795
123TRPM70.36360994
124INSRR0.36334674
125ERBB20.36023394
126WNK10.35626101
127AURKA0.35505499
128RPS6KA50.35041892
129BRSK10.33921534
130KIT0.33713570
131LATS20.33605203
132CAMK2B0.33324240
133VRK10.32832661
134CDK180.32547300
135AURKB0.31903670
136TNK20.31742429
137DYRK1B0.30580869
138PRKCE0.29378041
139PRKG10.29187575
140ARAF0.28543590
141EPHB20.28141346
142CDK10.27723639
143RIPK40.27315372
144CDK150.27313490
145MAP2K60.25736253
146PRKACA0.25479770

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.72910406
2Fanconi anemia pathway_Homo sapiens_hsa034602.79147211
3Nicotine addiction_Homo sapiens_hsa050332.79031927
4Butanoate metabolism_Homo sapiens_hsa006502.52720260
5Basal transcription factors_Homo sapiens_hsa030222.48866264
6Vitamin B6 metabolism_Homo sapiens_hsa007502.41080775
7Tryptophan metabolism_Homo sapiens_hsa003802.17548324
8Olfactory transduction_Homo sapiens_hsa047402.16636532
9ABC transporters_Homo sapiens_hsa020102.10713576
10Huntingtons disease_Homo sapiens_hsa050162.05645036
11Homologous recombination_Homo sapiens_hsa034401.87522622
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.86562122
13Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.86301059
14Collecting duct acid secretion_Homo sapiens_hsa049661.79152348
15Primary bile acid biosynthesis_Homo sapiens_hsa001201.78346871
16Nitrogen metabolism_Homo sapiens_hsa009101.77218156
17Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.75995751
18Oxidative phosphorylation_Homo sapiens_hsa001901.74713576
19beta-Alanine metabolism_Homo sapiens_hsa004101.71949010
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.71473753
21Synaptic vesicle cycle_Homo sapiens_hsa047211.71266103
22Steroid hormone biosynthesis_Homo sapiens_hsa001401.68347982
23Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.62829726
24Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.62665899
25Purine metabolism_Homo sapiens_hsa002301.60955568
26Chemical carcinogenesis_Homo sapiens_hsa052041.59685058
27Non-homologous end-joining_Homo sapiens_hsa034501.57384472
28Amphetamine addiction_Homo sapiens_hsa050311.57245229
29Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.55767049
30Histidine metabolism_Homo sapiens_hsa003401.55582231
31RNA polymerase_Homo sapiens_hsa030201.54459875
32RNA degradation_Homo sapiens_hsa030181.54320524
33Morphine addiction_Homo sapiens_hsa050321.46523336
34Fatty acid biosynthesis_Homo sapiens_hsa000611.45053755
35Linoleic acid metabolism_Homo sapiens_hsa005911.43188338
36RNA transport_Homo sapiens_hsa030131.43146114
37alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.41603212
38Taste transduction_Homo sapiens_hsa047421.39859141
39Oocyte meiosis_Homo sapiens_hsa041141.38660443
40Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.34640603
41Circadian entrainment_Homo sapiens_hsa047131.32809226
42Selenocompound metabolism_Homo sapiens_hsa004501.31949558
43Maturity onset diabetes of the young_Homo sapiens_hsa049501.31837865
44mRNA surveillance pathway_Homo sapiens_hsa030151.30816343
45Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.29751121
46Glutamatergic synapse_Homo sapiens_hsa047241.29454999
47Pyruvate metabolism_Homo sapiens_hsa006201.26238595
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.25692676
49Renin secretion_Homo sapiens_hsa049241.24728230
50Proteasome_Homo sapiens_hsa030501.24681134
51Cell cycle_Homo sapiens_hsa041101.22332487
52Insulin secretion_Homo sapiens_hsa049111.20505607
53Parkinsons disease_Homo sapiens_hsa050121.19986885
54Retinol metabolism_Homo sapiens_hsa008301.19982047
55Ether lipid metabolism_Homo sapiens_hsa005651.18430553
56Serotonergic synapse_Homo sapiens_hsa047261.18144828
57GABAergic synapse_Homo sapiens_hsa047271.16677482
58Long-term potentiation_Homo sapiens_hsa047201.15912494
59Cardiac muscle contraction_Homo sapiens_hsa042601.14118762
60Pyrimidine metabolism_Homo sapiens_hsa002401.09434751
61Fatty acid degradation_Homo sapiens_hsa000711.09421634
62Base excision repair_Homo sapiens_hsa034101.06128771
63Alzheimers disease_Homo sapiens_hsa050101.05968152
64Calcium signaling pathway_Homo sapiens_hsa040201.04962633
65Glucagon signaling pathway_Homo sapiens_hsa049221.03079645
66Nucleotide excision repair_Homo sapiens_hsa034201.02156943
67Spliceosome_Homo sapiens_hsa030401.01863154
68Caffeine metabolism_Homo sapiens_hsa002320.99990192
69Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.99142444
70Arachidonic acid metabolism_Homo sapiens_hsa005900.98792555
71Sphingolipid metabolism_Homo sapiens_hsa006000.94716363
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.94484376
73Dorso-ventral axis formation_Homo sapiens_hsa043200.93977031
74Peroxisome_Homo sapiens_hsa041460.93792232
75Glycerolipid metabolism_Homo sapiens_hsa005610.93625048
76Salivary secretion_Homo sapiens_hsa049700.92887302
77Circadian rhythm_Homo sapiens_hsa047100.91464649
78Wnt signaling pathway_Homo sapiens_hsa043100.90509665
79Basal cell carcinoma_Homo sapiens_hsa052170.88925820
80Hedgehog signaling pathway_Homo sapiens_hsa043400.87857539
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.86200609
82Fatty acid metabolism_Homo sapiens_hsa012120.86023388
83Dopaminergic synapse_Homo sapiens_hsa047280.84805166
84Regulation of autophagy_Homo sapiens_hsa041400.83769546
85Autoimmune thyroid disease_Homo sapiens_hsa053200.83220983
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.81190604
87Mismatch repair_Homo sapiens_hsa034300.81091995
88Glycerophospholipid metabolism_Homo sapiens_hsa005640.80346496
89Steroid biosynthesis_Homo sapiens_hsa001000.78192875
90Lysine degradation_Homo sapiens_hsa003100.76647594
91Fatty acid elongation_Homo sapiens_hsa000620.75448533
92Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.72527287
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70980713
94Vibrio cholerae infection_Homo sapiens_hsa051100.70013783
95SNARE interactions in vesicular transport_Homo sapiens_hsa041300.67949177
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.67713081
97Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.67405361
98Cholinergic synapse_Homo sapiens_hsa047250.67112565
99Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.66932021
100Rheumatoid arthritis_Homo sapiens_hsa053230.66738989
101Mineral absorption_Homo sapiens_hsa049780.65789716
102cGMP-PKG signaling pathway_Homo sapiens_hsa040220.63724213
103Cocaine addiction_Homo sapiens_hsa050300.62812323
104Axon guidance_Homo sapiens_hsa043600.62639379
105DNA replication_Homo sapiens_hsa030300.62048686
106cAMP signaling pathway_Homo sapiens_hsa040240.61466140
107Gastric acid secretion_Homo sapiens_hsa049710.61462406
108Ovarian steroidogenesis_Homo sapiens_hsa049130.60800133
109Alcoholism_Homo sapiens_hsa050340.60609999
110Tyrosine metabolism_Homo sapiens_hsa003500.60034314
111Melanogenesis_Homo sapiens_hsa049160.57735672
112One carbon pool by folate_Homo sapiens_hsa006700.57537289
113Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.55500849
114Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54029795
115Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.52219528
116Long-term depression_Homo sapiens_hsa047300.50466266
117Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49152288
118Vascular smooth muscle contraction_Homo sapiens_hsa042700.49081395
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48234080
120Oxytocin signaling pathway_Homo sapiens_hsa049210.46361503
121Glutathione metabolism_Homo sapiens_hsa004800.45006764
122Propanoate metabolism_Homo sapiens_hsa006400.43619890
123Type I diabetes mellitus_Homo sapiens_hsa049400.42051701
124Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40188777
125Aldosterone synthesis and secretion_Homo sapiens_hsa049250.39690014
126Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.39565024
127Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.39403733
128Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.39170937
129Phagosome_Homo sapiens_hsa041450.38609176
130Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.37285807
131Pancreatic secretion_Homo sapiens_hsa049720.36185719
132Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36050254
133Bile secretion_Homo sapiens_hsa049760.35992655
134Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.35848359
135Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.35238874
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35129456
137Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.32735426
138Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.32614788
139Carbohydrate digestion and absorption_Homo sapiens_hsa049730.32312899
140Epstein-Barr virus infection_Homo sapiens_hsa051690.31501988
141Metabolic pathways_Homo sapiens_hsa011000.31026376
142Hippo signaling pathway_Homo sapiens_hsa043900.28799985
143Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.28410432
144Protein export_Homo sapiens_hsa030600.26912420

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