Rank | Gene Set | Z-score |
---|---|---|
1 | urate metabolic process (GO:0046415) | 9.63947506 |
2 | drug transmembrane transport (GO:0006855) | 9.50673653 |
3 | drug transport (GO:0015893) | 7.94859086 |
4 | organic cation transport (GO:0015695) | 7.89198592 |
5 | phosphate ion transport (GO:0006817) | 7.66696401 |
6 | lysine catabolic process (GO:0006554) | 6.99383670 |
7 | lysine metabolic process (GO:0006553) | 6.99383670 |
8 | phosphate ion transmembrane transport (GO:0035435) | 6.42412122 |
9 | quaternary ammonium group transport (GO:0015697) | 6.28749100 |
10 | exogenous drug catabolic process (GO:0042738) | 6.09878228 |
11 | drug catabolic process (GO:0042737) | 6.03107471 |
12 | cysteine metabolic process (GO:0006534) | 5.82784058 |
13 | renal absorption (GO:0070293) | 5.78232066 |
14 | excretion (GO:0007588) | 5.76379318 |
15 | glyoxylate metabolic process (GO:0046487) | 5.67527528 |
16 | phosphate ion homeostasis (GO:0055062) | 5.56485199 |
17 | trivalent inorganic anion homeostasis (GO:0072506) | 5.56485199 |
18 | nonribosomal peptide biosynthetic process (GO:0019184) | 5.44245118 |
19 | response to mercury ion (GO:0046689) | 5.39495072 |
20 | vitamin D metabolic process (GO:0042359) | 5.24633985 |
21 | tricarboxylic acid metabolic process (GO:0072350) | 5.22450187 |
22 | toxin transport (GO:1901998) | 5.20242509 |
23 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.15251804 |
24 | negative regulation of cell killing (GO:0031342) | 5.15251804 |
25 | metanephric tubule development (GO:0072170) | 5.08420022 |
26 | metanephric nephron tubule development (GO:0072234) | 5.08420022 |
27 | surfactant homeostasis (GO:0043129) | 5.03184540 |
28 | glutathione biosynthetic process (GO:0006750) | 4.92540764 |
29 | branched-chain amino acid metabolic process (GO:0009081) | 4.86658492 |
30 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.79236332 |
31 | metanephric nephron epithelium development (GO:0072243) | 4.71680807 |
32 | short-chain fatty acid metabolic process (GO:0046459) | 4.69381349 |
33 | positive regulation by symbiont of host defense response (GO:0052509) | 4.69333432 |
34 | modulation by symbiont of host defense response (GO:0052031) | 4.69333432 |
35 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.69333432 |
36 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.69333432 |
37 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.69333432 |
38 | modulation by symbiont of host immune response (GO:0052553) | 4.69333432 |
39 | sodium-independent organic anion transport (GO:0043252) | 4.65460142 |
40 | valine metabolic process (GO:0006573) | 4.63880483 |
41 | amino-acid betaine transport (GO:0015838) | 4.55188208 |
42 | carnitine transport (GO:0015879) | 4.55188208 |
43 | glycoside metabolic process (GO:0016137) | 4.52236851 |
44 | aspartate family amino acid catabolic process (GO:0009068) | 4.44326558 |
45 | peptide catabolic process (GO:0043171) | 4.41974844 |
46 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.40502054 |
47 | activated T cell proliferation (GO:0050798) | 4.37142501 |
48 | microglial cell activation (GO:0001774) | 4.34822587 |
49 | metanephric epithelium development (GO:0072207) | 4.32490486 |
50 | nephron tubule development (GO:0072080) | 4.27970800 |
51 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.18017464 |
52 | homocysteine metabolic process (GO:0050667) | 4.15677152 |
53 | modified amino acid transport (GO:0072337) | 4.11523566 |
54 | cellular response to interleukin-15 (GO:0071350) | 4.09281776 |
55 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.08646354 |
56 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.06786151 |
57 | detection of molecule of bacterial origin (GO:0032490) | 4.04337515 |
58 | proline metabolic process (GO:0006560) | 4.00458748 |
59 | chemical homeostasis within a tissue (GO:0048875) | 3.98058276 |
60 | peptide biosynthetic process (GO:0043043) | 3.93882265 |
61 | branched-chain amino acid catabolic process (GO:0009083) | 3.93308486 |
62 | fatty acid beta-oxidation (GO:0006635) | 3.91990839 |
63 | response to interleukin-15 (GO:0070672) | 3.90608622 |
64 | macrophage activation involved in immune response (GO:0002281) | 3.85687031 |
65 | renal tubule development (GO:0061326) | 3.84989015 |
66 | cellular modified amino acid catabolic process (GO:0042219) | 3.84945487 |
67 | indolalkylamine catabolic process (GO:0046218) | 3.84794383 |
68 | tryptophan catabolic process (GO:0006569) | 3.84794383 |
69 | indole-containing compound catabolic process (GO:0042436) | 3.84794383 |
70 | amino-acid betaine metabolic process (GO:0006577) | 3.79270571 |
71 | aromatic amino acid family catabolic process (GO:0009074) | 3.78685950 |
72 | cellular extravasation (GO:0045123) | 3.76691170 |
73 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.74632808 |
74 | response to parathyroid hormone (GO:0071107) | 3.73525132 |
75 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.70717581 |
76 | L-phenylalanine metabolic process (GO:0006558) | 3.68994461 |
77 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.68994461 |
78 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.68519094 |
79 | interferon-gamma secretion (GO:0072643) | 3.65757941 |
80 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.64373314 |
81 | L-phenylalanine catabolic process (GO:0006559) | 3.63645128 |
82 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.63645128 |
83 | fatty acid oxidation (GO:0019395) | 3.62779807 |
84 | 2-oxoglutarate metabolic process (GO:0006103) | 3.61712257 |
85 | nephron epithelium morphogenesis (GO:0072088) | 3.61612173 |
86 | nephron tubule morphogenesis (GO:0072078) | 3.61612173 |
87 | tryptophan metabolic process (GO:0006568) | 3.60916462 |
88 | cellular response to vitamin D (GO:0071305) | 3.60574851 |
89 | serine family amino acid catabolic process (GO:0009071) | 3.59168175 |
90 | neutrophil activation (GO:0042119) | 3.58198067 |
91 | behavioral response to nicotine (GO:0035095) | 3.57930761 |
92 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.57419881 |
93 | polyol transport (GO:0015791) | 3.56063009 |
94 | lipid oxidation (GO:0034440) | 3.55717774 |
95 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.55576626 |
96 | serine family amino acid metabolic process (GO:0009069) | 3.55047622 |
97 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.54534113 |
98 | carnitine metabolic process (GO:0009437) | 3.54530431 |
99 | nephron epithelium development (GO:0072009) | 3.53796533 |
100 | fructose metabolic process (GO:0006000) | 3.52784714 |
101 | glutathione metabolic process (GO:0006749) | 3.52262808 |
102 | glutathione derivative metabolic process (GO:1901685) | 3.51847807 |
103 | glutathione derivative biosynthetic process (GO:1901687) | 3.51847807 |
104 | regulation of gamma-delta T cell activation (GO:0046643) | 3.51192831 |
105 | response to phenylpropanoid (GO:0080184) | 3.50164857 |
106 | negative regulation of interleukin-1 production (GO:0032692) | 3.49662863 |
107 | oligosaccharide catabolic process (GO:0009313) | 3.46399363 |
108 | acetyl-CoA metabolic process (GO:0006084) | 3.45378367 |
109 | sulfur compound transport (GO:0072348) | 3.43753701 |
110 | neutrophil activation involved in immune response (GO:0002283) | 3.43426087 |
111 | tolerance induction (GO:0002507) | 3.43388542 |
112 | detection of other organism (GO:0098543) | 3.40291720 |
113 | neutrophil mediated immunity (GO:0002446) | 3.39780237 |
114 | response to growth hormone (GO:0060416) | 3.39660279 |
115 | detection of external biotic stimulus (GO:0098581) | 3.38509313 |
116 | negative regulation of T cell mediated immunity (GO:0002710) | 3.36150808 |
117 | vitamin transport (GO:0051180) | 3.34553032 |
118 | sulfate transmembrane transport (GO:1902358) | 3.33651468 |
119 | cellular response to vitamin (GO:0071295) | 3.32316415 |
120 | L-ascorbic acid metabolic process (GO:0019852) | 3.29600572 |
121 | glucuronate metabolic process (GO:0019585) | 3.27128639 |
122 | uronic acid metabolic process (GO:0006063) | 3.27128639 |
123 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.26289665 |
124 | negative regulation of interleukin-12 production (GO:0032695) | 3.25832534 |
125 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.25139373 |
126 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.23959828 |
127 | response to host immune response (GO:0052572) | 3.23959828 |
128 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.23068188 |
129 | thyroid hormone metabolic process (GO:0042403) | 3.20993082 |
130 | macrophage activation (GO:0042116) | 3.20013841 |
131 | positive regulation of mast cell activation (GO:0033005) | 3.19151602 |
132 | DNA deamination (GO:0045006) | 3.18383502 |
133 | fatty acid catabolic process (GO:0009062) | 3.15948015 |
134 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.15278077 |
135 | cellular ketone body metabolic process (GO:0046950) | 3.14546939 |
136 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.13770188 |
137 | response to magnesium ion (GO:0032026) | 3.13680800 |
138 | regulation of germinal center formation (GO:0002634) | 3.10986487 |
139 | thyroid hormone generation (GO:0006590) | 3.10773640 |
140 | biotin metabolic process (GO:0006768) | 3.10704322 |
141 | response to thyroid hormone (GO:0097066) | 3.10133028 |
142 | cobalamin metabolic process (GO:0009235) | 3.10056638 |
143 | renal tubule morphogenesis (GO:0061333) | 3.08517416 |
144 | leukocyte aggregation (GO:0070486) | 3.07580699 |
145 | sulfur amino acid catabolic process (GO:0000098) | 3.07159006 |
146 | sodium ion transport (GO:0006814) | 3.07103294 |
147 | regulation of mast cell activation (GO:0033003) | 3.05837657 |
148 | glutamate metabolic process (GO:0006536) | 3.05127242 |
149 | detection of bacterium (GO:0016045) | 3.05039745 |
150 | cellular amino acid catabolic process (GO:0009063) | 3.03379625 |
151 | regulation of memory T cell differentiation (GO:0043380) | 3.02727212 |
152 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 3.02193542 |
153 | regulation of regulatory T cell differentiation (GO:0045589) | 3.01194084 |
154 | dendritic cell migration (GO:0036336) | 3.00210671 |
155 | myeloid leukocyte mediated immunity (GO:0002444) | 2.98732209 |
156 | granulocyte activation (GO:0036230) | 2.97916789 |
157 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 2.97505484 |
158 | indole-containing compound metabolic process (GO:0042430) | 2.97361284 |
159 | NADH metabolic process (GO:0006734) | 2.95891307 |
160 | detection of biotic stimulus (GO:0009595) | 2.94954510 |
161 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.94446591 |
162 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.94446591 |
163 | myeloid cell activation involved in immune response (GO:0002275) | 2.93318269 |
164 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.92446687 |
165 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.92222431 |
166 | positive regulation of interferon-alpha production (GO:0032727) | 2.91945684 |
167 | respiratory burst (GO:0045730) | 2.91115458 |
168 | sulfation (GO:0051923) | 2.91015010 |
169 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.87819909 |
170 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.83377513 |
171 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.82701554 |
172 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 2.80375751 |
173 | negative regulation of B cell mediated immunity (GO:0002713) | 2.79567597 |
174 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.79567597 |
175 | mast cell activation (GO:0045576) | 2.78820127 |
176 | regulation of interferon-alpha production (GO:0032647) | 2.76513893 |
177 | response to host defenses (GO:0052200) | 2.74984721 |
178 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.74984721 |
179 | response to host (GO:0075136) | 2.74984721 |
180 | dendritic cell chemotaxis (GO:0002407) | 2.74871748 |
181 | superoxide anion generation (GO:0042554) | 2.74095662 |
182 | leukocyte degranulation (GO:0043299) | 2.73095930 |
183 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.70987661 |
184 | cellular response to exogenous dsRNA (GO:0071360) | 2.65582235 |
185 | positive regulation of defense response to virus by host (GO:0002230) | 2.64548808 |
186 | negative regulation of adaptive immune response (GO:0002820) | 2.64062623 |
187 | response to interferon-beta (GO:0035456) | 2.63423275 |
188 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.62087376 |
189 | positive regulation of mast cell degranulation (GO:0043306) | 2.60976220 |
190 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.60976220 |
191 | response to type I interferon (GO:0034340) | 2.60657601 |
192 | negative regulation of interleukin-6 production (GO:0032715) | 2.60486343 |
193 | membrane repolarization during action potential (GO:0086011) | 2.59790423 |
194 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.59303825 |
195 | T cell mediated immunity (GO:0002456) | 2.58211562 |
196 | cytidine deamination (GO:0009972) | 2.58200512 |
197 | cytidine metabolic process (GO:0046087) | 2.58200512 |
198 | cytidine catabolic process (GO:0006216) | 2.58200512 |
199 | response to peptidoglycan (GO:0032494) | 2.56188526 |
200 | aminoglycoside antibiotic metabolic process (GO:0030647) | 10.3371890 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.19042922 |
2 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.53749751 |
3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.46344865 |
4 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.28175588 |
5 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.24695632 |
6 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.19869348 |
7 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 3.11077116 |
8 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 3.10035169 |
9 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.94516443 |
10 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.62783276 |
11 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.59924827 |
12 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.54195080 |
13 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.53604613 |
14 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.44085214 |
15 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.42663834 |
16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.33638145 |
17 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.33352111 |
18 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.28164727 |
19 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.27366898 |
20 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.13342834 |
21 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 2.10078928 |
22 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.90994451 |
23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.86544847 |
24 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.86198921 |
25 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.80416066 |
26 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.80030898 |
27 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.76215277 |
28 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.73615366 |
29 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.69817006 |
30 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.68631903 |
31 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.66466676 |
32 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.66203128 |
33 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.65761733 |
34 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.64056742 |
35 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.59847004 |
36 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.57351535 |
37 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.56075204 |
38 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.54749759 |
39 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.52003739 |
40 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.51219785 |
41 | GATA3_26560356_Chip-Seq_TH2_Human | 1.49140677 |
42 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.49067005 |
43 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.47966393 |
44 | * FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.45691081 |
45 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.45512102 |
46 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.44446908 |
47 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.44358815 |
48 | * STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.43553730 |
49 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.43313868 |
50 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.42843406 |
51 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.42287284 |
52 | VDR_22108803_ChIP-Seq_LS180_Human | 1.42042061 |
53 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.41289763 |
54 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.40902472 |
55 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.40837573 |
56 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.39362794 |
57 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.38041809 |
58 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.37924337 |
59 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.35561840 |
60 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.35441508 |
61 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.34891384 |
62 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.34347362 |
63 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.33581300 |
64 | P300_19829295_ChIP-Seq_ESCs_Human | 1.32834588 |
65 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.31554840 |
66 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.31088630 |
67 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.29059230 |
68 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.28104448 |
69 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.27347034 |
70 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.26653197 |
71 | * LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25792458 |
72 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.25684834 |
73 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.25555032 |
74 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.25471993 |
75 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.25471993 |
76 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.25143839 |
77 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.24721542 |
78 | MYB_26560356_Chip-Seq_TH2_Human | 1.23594400 |
79 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.23283302 |
80 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.23194999 |
81 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.22764104 |
82 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.22762178 |
83 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.22261748 |
84 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.21756685 |
85 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.20884627 |
86 | GATA1_22025678_ChIP-Seq_K562_Human | 1.19887911 |
87 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.19664043 |
88 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.19586283 |
89 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.19486743 |
90 | TP53_16413492_ChIP-PET_HCT116_Human | 1.18806283 |
91 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.18114908 |
92 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.18114908 |
93 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.17185660 |
94 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.17091093 |
95 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.16771798 |
96 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.16657102 |
97 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.14952818 |
98 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.13857768 |
99 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.13842934 |
100 | * RXR_22108803_ChIP-Seq_LS180_Human | 1.13001252 |
101 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.11801344 |
102 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.11742637 |
103 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.11742637 |
104 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.11516544 |
105 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.11346419 |
106 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11346419 |
107 | * GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11037606 |
108 | * CJUN_26792858_Chip-Seq_BT549_Human | 1.11015355 |
109 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.10409508 |
110 | STAT3_23295773_ChIP-Seq_U87_Human | 1.10372381 |
111 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.10338119 |
112 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.08223623 |
113 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.07520546 |
114 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.06808839 |
115 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.05786646 |
116 | * SMRT_27268052_Chip-Seq_Bcells_Human | 1.05527966 |
117 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.04800255 |
118 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.04628725 |
119 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.04042861 |
120 | * GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.03533305 |
121 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.03384549 |
122 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.03384549 |
123 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.03141750 |
124 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.03133133 |
125 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.02845510 |
126 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.02231581 |
127 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.02142383 |
128 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.02130476 |
129 | EWS_26573619_Chip-Seq_HEK293_Human | 1.01770898 |
130 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.01437834 |
131 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.01341022 |
132 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 1.01134325 |
133 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.00357355 |
134 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.00322664 |
135 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.00274095 |
136 | AR_25329375_ChIP-Seq_VCAP_Human | 1.00273809 |
137 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.00088154 |
138 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.99962244 |
139 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.99541727 |
140 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99333084 |
141 | TCF4_23295773_ChIP-Seq_U87_Human | 0.98851596 |
142 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98790261 |
143 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.98477945 |
144 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.98457106 |
145 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98352143 |
146 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98128591 |
147 | * TP63_23658742_ChIP-Seq_EP156T_Human | 0.96569470 |
148 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.96542075 |
149 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.96429819 |
150 | * OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.96327184 |
151 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.95930694 |
152 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.95898256 |
153 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.95560144 |
154 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.95235278 |
155 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.94903459 |
156 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.94894961 |
157 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.94799354 |
158 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.94637770 |
159 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.94607396 |
160 | SPI1_23127762_ChIP-Seq_K562_Human | 0.92499046 |
161 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.92381303 |
162 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.92220300 |
163 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.92203130 |
164 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91937485 |
165 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91511830 |
166 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.90576125 |
167 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.90034072 |
168 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.89835603 |
169 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.89814119 |
170 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89695594 |
171 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89672625 |
172 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.89421599 |
173 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.88683682 |
174 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.88656487 |
175 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.88163456 |
176 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.88111308 |
177 | * FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.87412627 |
178 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.85924190 |
179 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.85839053 |
180 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.85697251 |
181 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.81723272 |
182 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.81158496 |
183 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.81046998 |
184 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.80642924 |
185 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.79968711 |
186 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.77923452 |
187 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.77532137 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 6.51235917 |
2 | MP0004043_abnormal_pH_regulation | 5.97771420 |
3 | MP0004019_abnormal_vitamin_homeostasis | 4.83706694 |
4 | MP0005332_abnormal_amino_acid | 4.45286809 |
5 | MP0002138_abnormal_hepatobiliary_system | 4.41250274 |
6 | MP0002139_abnormal_hepatobiliary_system | 3.85875883 |
7 | MP0001958_emphysema | 3.81131057 |
8 | MP0009643_abnormal_urine_homeostasis | 3.75804806 |
9 | MP0000569_abnormal_digit_pigmentation | 3.75197205 |
10 | MP0001765_abnormal_ion_homeostasis | 3.66020194 |
11 | MP0003195_calcinosis | 3.45979683 |
12 | MP0003878_abnormal_ear_physiology | 3.16803515 |
13 | MP0005377_hearing/vestibular/ear_phenot | 3.16803515 |
14 | MP0003436_decreased_susceptibility_to | 3.00794114 |
15 | MP0005671_abnormal_response_to | 2.99418358 |
16 | MP0001756_abnormal_urination | 2.94144073 |
17 | MP0002136_abnormal_kidney_physiology | 2.93749963 |
18 | MP0005636_abnormal_mineral_homeostasis | 2.86613619 |
19 | MP0001835_abnormal_antigen_presentation | 2.66677716 |
20 | MP0008875_abnormal_xenobiotic_pharmacok | 2.60180264 |
21 | MP0000685_abnormal_immune_system | 2.52339304 |
22 | MP0001800_abnormal_humoral_immune | 2.51469214 |
23 | MP0002277_abnormal_respiratory_mucosa | 2.50348864 |
24 | MP0009785_altered_susceptibility_to | 2.43886490 |
25 | MP0002419_abnormal_innate_immunity | 2.32616683 |
26 | MP0008877_abnormal_DNA_methylation | 2.22316184 |
27 | MP0005387_immune_system_phenotype | 2.19170656 |
28 | MP0001790_abnormal_immune_system | 2.19170656 |
29 | MP0002723_abnormal_immune_serum | 2.16739467 |
30 | MP0005000_abnormal_immune_tolerance | 2.11795621 |
31 | MP0005025_abnormal_response_to | 2.10301579 |
32 | MP0003252_abnormal_bile_duct | 2.10279313 |
33 | MP0002876_abnormal_thyroid_physiology | 2.01788141 |
34 | MP0002452_abnormal_antigen_presenting | 2.01192716 |
35 | MP0002420_abnormal_adaptive_immunity | 1.96149818 |
36 | MP0001819_abnormal_immune_cell | 1.95835816 |
37 | MP0005058_abnormal_lysosome_morphology | 1.92757775 |
38 | MP0000538_abnormal_urinary_bladder | 1.89276473 |
39 | MP0002148_abnormal_hypersensitivity_rea | 1.88628412 |
40 | MP0008004_abnormal_stomach_pH | 1.80018384 |
41 | MP0005365_abnormal_bile_salt | 1.79160009 |
42 | MP0001533_abnormal_skeleton_physiology | 1.75421803 |
43 | MP0003186_abnormal_redox_activity | 1.74087190 |
44 | MP0004782_abnormal_surfactant_physiolog | 1.72972811 |
45 | MP0005085_abnormal_gallbladder_physiolo | 1.72216435 |
46 | MP0002653_abnormal_ependyma_morphology | 1.70536512 |
47 | MP0004130_abnormal_muscle_cell | 1.64453609 |
48 | MP0003303_peritoneal_inflammation | 1.59689738 |
49 | MP0002405_respiratory_system_inflammati | 1.57598561 |
50 | MP0001501_abnormal_sleep_pattern | 1.52778479 |
51 | MP0002168_other_aberrant_phenotype | 1.51239001 |
52 | MP0004885_abnormal_endolymph | 1.49369589 |
53 | MP0008961_abnormal_basal_metabolism | 1.45592529 |
54 | MP0003300_gastrointestinal_ulcer | 1.44516559 |
55 | MP0000716_abnormal_immune_system | 1.39372124 |
56 | MP0005084_abnormal_gallbladder_morpholo | 1.37690344 |
57 | MP0003787_abnormal_imprinting | 1.36282923 |
58 | MP0002928_abnormal_bile_duct | 1.36017582 |
59 | MP0005174_abnormal_tail_pigmentation | 1.34722373 |
60 | MP0000465_gastrointestinal_hemorrhage | 1.34117823 |
61 | MP0001845_abnormal_inflammatory_respons | 1.32370151 |
62 | MP0005670_abnormal_white_adipose | 1.32164002 |
63 | MP0003646_muscle_fatigue | 1.31618031 |
64 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.30496836 |
65 | MP0003866_abnormal_defecation | 1.29841852 |
66 | MP0004381_abnormal_hair_follicle | 1.28333227 |
67 | MP0006082_CNS_inflammation | 1.27851794 |
68 | MP0004883_abnormal_blood_vessel | 1.26270547 |
69 | MP0002254_reproductive_system_inflammat | 1.24945826 |
70 | MP0001986_abnormal_taste_sensitivity | 1.24780130 |
71 | MP0004142_abnormal_muscle_tone | 1.21305328 |
72 | MP0001968_abnormal_touch/_nociception | 1.16610091 |
73 | MP0002398_abnormal_bone_marrow | 1.14583265 |
74 | MP0002102_abnormal_ear_morphology | 1.14487401 |
75 | MP0000689_abnormal_spleen_morphology | 1.14108512 |
76 | MP0002896_abnormal_bone_mineralization | 1.13461662 |
77 | MP0005319_abnormal_enzyme/_coenzyme | 1.12947417 |
78 | MP0000678_abnormal_parathyroid_gland | 1.12214837 |
79 | MP0002135_abnormal_kidney_morphology | 1.10276797 |
80 | MP0008872_abnormal_physiological_respon | 1.09472397 |
81 | MP0003191_abnormal_cellular_cholesterol | 1.09462687 |
82 | MP0003724_increased_susceptibility_to | 1.09034601 |
83 | MP0004272_abnormal_basement_membrane | 1.08840709 |
84 | MP0009745_abnormal_behavioral_response | 1.08355416 |
85 | MP0000230_abnormal_systemic_arterial | 1.06811588 |
86 | MP0003763_abnormal_thymus_physiology | 1.06786543 |
87 | MP0001440_abnormal_grooming_behavior | 1.06091511 |
88 | MP0005551_abnormal_eye_electrophysiolog | 1.03809521 |
89 | MP0005666_abnormal_adipose_tissue | 1.03739197 |
90 | MP0002796_impaired_skin_barrier | 1.03684658 |
91 | MP0001177_atelectasis | 1.02375253 |
92 | MP0010234_abnormal_vibrissa_follicle | 1.02052169 |
93 | MP0005164_abnormal_response_to | 1.01987598 |
94 | MP0003011_delayed_dark_adaptation | 0.99087681 |
95 | MP0002722_abnormal_immune_system | 0.99017517 |
96 | MP0005075_abnormal_melanosome_morpholog | 0.97693886 |
97 | MP0008469_abnormal_protein_level | 0.97524308 |
98 | MP0004264_abnormal_extraembryonic_tissu | 0.97031795 |
99 | MP0005451_abnormal_body_composition | 0.96596942 |
100 | MP0002429_abnormal_blood_cell | 0.94467758 |
101 | MP0002098_abnormal_vibrissa_morphology | 0.93260615 |
102 | MP0000427_abnormal_hair_cycle | 0.92610865 |
103 | MP0001666_abnormal_nutrient_absorption | 0.91448652 |
104 | MP0001486_abnormal_startle_reflex | 0.91438038 |
105 | MP0003183_abnormal_peptide_metabolism | 0.89552308 |
106 | MP0010155_abnormal_intestine_physiology | 0.88797806 |
107 | MP0004147_increased_porphyrin_level | 0.87381663 |
108 | MP0003828_pulmonary_edema | 0.86810431 |
109 | MP0005535_abnormal_body_temperature | 0.85600814 |
110 | MP0002272_abnormal_nervous_system | 0.85556294 |
111 | MP0003638_abnormal_response/metabolism_ | 0.85549685 |
112 | MP0001919_abnormal_reproductive_system | 0.85494906 |
113 | MP0005464_abnormal_platelet_physiology | 0.85015067 |
114 | MP0000470_abnormal_stomach_morphology | 0.81014003 |
115 | MP0005389_reproductive_system_phenotype | 0.80991834 |
116 | MP0003045_fibrosis | 0.80712665 |
117 | MP0000383_abnormal_hair_follicle | 0.80620166 |
118 | MP0009764_decreased_sensitivity_to | 0.80451818 |
119 | MP0002118_abnormal_lipid_homeostasis | 0.80115322 |
120 | MP0002295_abnormal_pulmonary_circulatio | 0.79630406 |
121 | MP0002133_abnormal_respiratory_system | 0.76568833 |
122 | MP0005388_respiratory_system_phenotype | 0.76568833 |
123 | MP0000703_abnormal_thymus_morphology | 0.75966835 |
124 | MP0000631_abnormal_neuroendocrine_gland | 0.75577919 |
125 | MP0002132_abnormal_respiratory_system | 0.73934209 |
126 | MP0004947_skin_inflammation | 0.73887206 |
127 | MP0002693_abnormal_pancreas_physiology | 0.72951123 |
128 | MP0005167_abnormal_blood-brain_barrier | 0.72643793 |
129 | MP0002064_seizures | 0.71508362 |
130 | MP0002089_abnormal_postnatal_growth/wei | 0.70270366 |
131 | MP0002735_abnormal_chemical_nociception | 0.70232756 |
132 | MP0005395_other_phenotype | 0.69698635 |
133 | MP0001485_abnormal_pinna_reflex | 0.68791617 |
134 | MP0005390_skeleton_phenotype | 0.68231523 |
135 | MP0003879_abnormal_hair_cell | 0.67752596 |
136 | MP0001664_abnormal_digestion | 0.67699978 |
137 | MP0003283_abnormal_digestive_organ | 0.66775515 |
138 | MP0002733_abnormal_thermal_nociception | 0.66641759 |
139 | MP0005165_increased_susceptibility_to | 0.66525293 |
140 | MP0002998_abnormal_bone_remodeling | 0.66408070 |
141 | MP0002166_altered_tumor_susceptibility | 0.66195803 |
142 | MP0010386_abnormal_urinary_bladder | 0.66132707 |
143 | MP0002115_abnormal_skeleton_extremities | 0.65134297 |
144 | MP0001873_stomach_inflammation | 0.64590165 |
145 | MP0005501_abnormal_skin_physiology | 0.64058963 |
146 | MP0002332_abnormal_exercise_endurance | 0.63342246 |
147 | MP0000681_abnormal_thyroid_gland | 0.62501988 |
148 | MP0006036_abnormal_mitochondrial_physio | 0.62458400 |
149 | MP0001661_extended_life_span | 0.62117275 |
150 | MP0001346_abnormal_lacrimal_gland | 0.61642282 |
151 | MP0009642_abnormal_blood_homeostasis | 0.60315726 |
152 | MP0001764_abnormal_homeostasis | 0.60038732 |
153 | MP0000163_abnormal_cartilage_morphology | 0.59489829 |
154 | MP0005408_hypopigmentation | 0.58800927 |
155 | MP0003795_abnormal_bone_structure | 0.58040411 |
156 | MP0000534_abnormal_ureter_morphology | 0.57529589 |
157 | MP0004742_abnormal_vestibular_system | 0.55877099 |
158 | MP0003806_abnormal_nucleotide_metabolis | 0.55716895 |
159 | MP0005220_abnormal_exocrine_pancreas | 0.54933174 |
160 | MP0009780_abnormal_chondrocyte_physiolo | 0.53952342 |
161 | MP0004484_altered_response_of | 0.53536377 |
162 | MP0000762_abnormal_tongue_morphology | 0.53470507 |
163 | MP0000371_diluted_coat_color | 0.53436308 |
164 | MP0005275_abnormal_skin_tensile | 0.53221569 |
165 | MP0004858_abnormal_nervous_system | 0.50301591 |
166 | MP0003172_abnormal_lysosome_physiology | 0.50000664 |
167 | MP0001663_abnormal_digestive_system | 0.45990616 |
168 | MP0005375_adipose_tissue_phenotype | 0.45836982 |
169 | MP0010329_abnormal_lipoprotein_level | 0.45733748 |
170 | MP0003566_abnormal_cell_adhesion | 0.45158708 |
171 | MP0005310_abnormal_salivary_gland | 0.45127069 |
172 | MP0003959_abnormal_lean_body | 0.44857058 |
173 | MP0005083_abnormal_biliary_tract | 0.42009174 |
174 | MP0003075_altered_response_to | 0.41280745 |
175 | MP0008438_abnormal_cutaneous_collagen | 0.41180248 |
176 | MP0000609_abnormal_liver_physiology | 0.38341383 |
177 | MP0003953_abnormal_hormone_level | 0.37776853 |
178 | MP0002113_abnormal_skeleton_development | 0.37759310 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Increased circulating renin level (HP:0000848) | 7.57993277 |
2 | Hyperactive renin-angiotensin system (HP:0000841) | 7.41537119 |
3 | Hypokalemic alkalosis (HP:0001949) | 7.15822322 |
4 | Metabolic alkalosis (HP:0200114) | 7.05387076 |
5 | Gout (HP:0001997) | 7.01515230 |
6 | Hypomagnesemia (HP:0002917) | 6.85043881 |
7 | Abnormality of chloride homeostasis (HP:0011422) | 6.54506981 |
8 | Polyuria (HP:0000103) | 6.35982173 |
9 | Abnormality of renal excretion (HP:0011036) | 6.01620204 |
10 | Abnormal urine output (HP:0012590) | 5.98563070 |
11 | Abnormality of magnesium homeostasis (HP:0004921) | 5.73656868 |
12 | Tetany (HP:0001281) | 5.26670738 |
13 | Proximal tubulopathy (HP:0000114) | 5.24315592 |
14 | Abnormal drinking behavior (HP:0030082) | 5.11623998 |
15 | Polydipsia (HP:0001959) | 5.11623998 |
16 | Renal salt wasting (HP:0000127) | 5.11265985 |
17 | Abnormality of renin-angiotensin system (HP:0000847) | 5.02225274 |
18 | Increased purine levels (HP:0004368) | 5.01284529 |
19 | Hyperuricemia (HP:0002149) | 5.01284529 |
20 | Hyperaldosteronism (HP:0000859) | 4.86698017 |
21 | Myositis (HP:0100614) | 4.67255656 |
22 | Retrobulbar optic neuritis (HP:0100654) | 4.66156777 |
23 | Optic neuritis (HP:0100653) | 4.66156777 |
24 | Orchitis (HP:0100796) | 4.55444287 |
25 | Alkalosis (HP:0001948) | 4.51379992 |
26 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.43411186 |
27 | Abnormality of purine metabolism (HP:0004352) | 4.43271693 |
28 | Hyperglycinuria (HP:0003108) | 4.33515475 |
29 | Stomatitis (HP:0010280) | 4.21452363 |
30 | Hypercalciuria (HP:0002150) | 3.97063908 |
31 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.86351054 |
32 | Generalized aminoaciduria (HP:0002909) | 3.75514667 |
33 | Eczematoid dermatitis (HP:0000976) | 3.71673011 |
34 | Renal tubular acidosis (HP:0001947) | 3.67491901 |
35 | Recurrent bacterial skin infections (HP:0005406) | 3.66288178 |
36 | Hypokalemia (HP:0002900) | 3.66057258 |
37 | Recurrent abscess formation (HP:0002722) | 3.51975899 |
38 | Abnormality of glycine metabolism (HP:0010895) | 3.50227472 |
39 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.50227472 |
40 | Glycosuria (HP:0003076) | 3.48187104 |
41 | Abnormality of urine glucose concentration (HP:0011016) | 3.48187104 |
42 | Keratoconjunctivitis (HP:0001096) | 3.44560612 |
43 | Keratoconjunctivitis sicca (HP:0001097) | 3.37860541 |
44 | Pancreatic cysts (HP:0001737) | 3.37170245 |
45 | Ketoacidosis (HP:0001993) | 3.34757634 |
46 | Abnormality of potassium homeostasis (HP:0011042) | 3.27789653 |
47 | Abnormality of proline metabolism (HP:0010907) | 3.19488268 |
48 | Hydroxyprolinuria (HP:0003080) | 3.19488268 |
49 | Recurrent fungal infections (HP:0002841) | 3.12675849 |
50 | Encephalitis (HP:0002383) | 3.12270144 |
51 | Hypochromic microcytic anemia (HP:0004840) | 3.11828935 |
52 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.11344946 |
53 | Abnormality of nucleobase metabolism (HP:0010932) | 3.11178289 |
54 | Stomach cancer (HP:0012126) | 3.01132491 |
55 | Hyperphosphaturia (HP:0003109) | 2.96603925 |
56 | Nephrocalcinosis (HP:0000121) | 2.95261271 |
57 | Congenital stationary night blindness (HP:0007642) | 2.92841903 |
58 | Abnormal urine phosphate concentration (HP:0012599) | 2.91894890 |
59 | Delayed epiphyseal ossification (HP:0002663) | 2.90196283 |
60 | Vascular calcification (HP:0004934) | 2.86318943 |
61 | Gastrointestinal infarctions (HP:0005244) | 2.85691172 |
62 | Thyroid-stimulating hormone excess (HP:0002925) | 2.84301169 |
63 | Tubulointerstitial fibrosis (HP:0005576) | 2.83160660 |
64 | Clumsiness (HP:0002312) | 2.82229347 |
65 | Ketosis (HP:0001946) | 2.81563503 |
66 | Congenital, generalized hypertrichosis (HP:0004540) | 2.80666660 |
67 | Pancreatic fibrosis (HP:0100732) | 2.79927753 |
68 | Congenital sensorineural hearing impairment (HP:0008527) | 2.77968725 |
69 | Genetic anticipation (HP:0003743) | 2.77299933 |
70 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.73916405 |
71 | Recurrent cutaneous fungal infections (HP:0011370) | 2.73916405 |
72 | Abnormality of T cell number (HP:0011839) | 2.72578476 |
73 | Nephrolithiasis (HP:0000787) | 2.72199206 |
74 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.71851958 |
75 | Dehydration (HP:0001944) | 2.71130844 |
76 | Mediastinal lymphadenopathy (HP:0100721) | 2.70946256 |
77 | True hermaphroditism (HP:0010459) | 2.68486668 |
78 | Cardiovascular calcification (HP:0011915) | 2.67663147 |
79 | Hyperventilation (HP:0002883) | 2.65886536 |
80 | T lymphocytopenia (HP:0005403) | 2.63616845 |
81 | Abnormality of macrophages (HP:0004311) | 2.60101470 |
82 | Goiter (HP:0000853) | 2.57571156 |
83 | Abnormality of midbrain morphology (HP:0002418) | 2.55782530 |
84 | Molar tooth sign on MRI (HP:0002419) | 2.55782530 |
85 | Hypophosphatemia (HP:0002148) | 2.55467271 |
86 | Hypochromic anemia (HP:0001931) | 2.55366082 |
87 | Recurrent skin infections (HP:0001581) | 2.55124740 |
88 | Rickets (HP:0002748) | 2.52785103 |
89 | Widely patent fontanelles and sutures (HP:0004492) | 2.51666774 |
90 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.51529495 |
91 | Absent/shortened dynein arms (HP:0200106) | 2.50140387 |
92 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.50140387 |
93 | Vacuolated lymphocytes (HP:0001922) | 2.49073158 |
94 | Delayed CNS myelination (HP:0002188) | 2.48983019 |
95 | Progressive cerebellar ataxia (HP:0002073) | 2.47236923 |
96 | Tubular atrophy (HP:0000092) | 2.44654768 |
97 | Abolished electroretinogram (ERG) (HP:0000550) | 2.43908714 |
98 | Hemoptysis (HP:0002105) | 2.42761371 |
99 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.41885496 |
100 | Nephronophthisis (HP:0000090) | 2.37931281 |
101 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.37573363 |
102 | Pulmonary infiltrates (HP:0002113) | 2.35987426 |
103 | Hyperglycinemia (HP:0002154) | 2.33980859 |
104 | Vasculitis (HP:0002633) | 2.33529581 |
105 | Ventricular fibrillation (HP:0001663) | 2.33228649 |
106 | Inability to walk (HP:0002540) | 2.31890626 |
107 | Anorexia (HP:0002039) | 2.31780018 |
108 | Hyponatremia (HP:0002902) | 2.31397206 |
109 | Meningitis (HP:0001287) | 2.30716610 |
110 | Abnormality of sodium homeostasis (HP:0010931) | 2.29826531 |
111 | Adrenal overactivity (HP:0002717) | 2.29627075 |
112 | Abnormality of the renal medulla (HP:0100957) | 2.29587163 |
113 | Episodic fever (HP:0001954) | 2.29290643 |
114 | Abnormality of T cells (HP:0002843) | 2.29144534 |
115 | Progressive inability to walk (HP:0002505) | 2.28494998 |
116 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.28043884 |
117 | Attenuation of retinal blood vessels (HP:0007843) | 2.27602419 |
118 | Abnormality of renal resorption (HP:0011038) | 2.27534466 |
119 | Renal tubular dysfunction (HP:0000124) | 2.24501430 |
120 | Enlarged kidneys (HP:0000105) | 2.24481194 |
121 | Tachypnea (HP:0002789) | 2.23984300 |
122 | Metaphyseal cupping (HP:0003021) | 2.23380783 |
123 | Furrowed tongue (HP:0000221) | 2.22166108 |
124 | Leukocytosis (HP:0001974) | 2.19271424 |
125 | IgG deficiency (HP:0004315) | 2.16024725 |
126 | Potter facies (HP:0002009) | 2.15987822 |
127 | Facial shape deformation (HP:0011334) | 2.15987822 |
128 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.15760153 |
129 | Thin bony cortex (HP:0002753) | 2.14564867 |
130 | Decreased central vision (HP:0007663) | 2.12360648 |
131 | Hemiplegia (HP:0002301) | 2.12054633 |
132 | Hyperkalemia (HP:0002153) | 2.11661329 |
133 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.08253141 |
134 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.07944038 |
135 | Large for gestational age (HP:0001520) | 2.07832799 |
136 | Malnutrition (HP:0004395) | 2.06918870 |
137 | Abnormal enzyme/coenzyme activity (HP:0012379) | 2.06433831 |
138 | Metabolic acidosis (HP:0001942) | 2.05842987 |
139 | Vomiting (HP:0002013) | 2.02346722 |
140 | Confusion (HP:0001289) | 2.01050968 |
141 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.99715001 |
142 | Dicarboxylic aciduria (HP:0003215) | 1.99417973 |
143 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.99417973 |
144 | Chronic obstructive pulmonary disease (HP:0006510) | 1.99059318 |
145 | Obstructive lung disease (HP:0006536) | 1.99059318 |
146 | Agitation (HP:0000713) | 1.99022233 |
147 | Abnormality of T cell physiology (HP:0011840) | 1.96567250 |
148 | Chronic otitis media (HP:0000389) | 1.95645864 |
149 | Tubulointerstitial abnormality (HP:0001969) | 1.94392346 |
150 | Urticaria (HP:0001025) | 1.93807778 |
151 | Chondrocalcinosis (HP:0000934) | 1.93586331 |
152 | Decreased circulating renin level (HP:0003351) | 1.92786941 |
153 | Hyperammonemia (HP:0001987) | 1.92689108 |
154 | Gaze-evoked nystagmus (HP:0000640) | 1.91565022 |
155 | Abnormality of eosinophils (HP:0001879) | 1.90737744 |
156 | Pustule (HP:0200039) | 1.90424729 |
157 | Increased IgE level (HP:0003212) | 1.89639587 |
158 | Abnormality of the pleura (HP:0002103) | 1.89365325 |
159 | Peritonitis (HP:0002586) | 1.88338112 |
160 | Abnormality of alanine metabolism (HP:0010916) | 1.88212118 |
161 | Hyperalaninemia (HP:0003348) | 1.88212118 |
162 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.88212118 |
163 | Cheilitis (HP:0100825) | 1.87518852 |
164 | Keratitis (HP:0000491) | 1.87109259 |
165 | Abnormality of Sharpey fibers (HP:0100685) | 1.86398457 |
166 | Spontaneous hematomas (HP:0007420) | 1.85971756 |
167 | Metaphyseal irregularity (HP:0003025) | 1.84959307 |
168 | Methylmalonic aciduria (HP:0012120) | 1.84510050 |
169 | Interstitial pulmonary disease (HP:0006530) | 1.83698691 |
170 | Glomerulosclerosis (HP:0000096) | 1.83191670 |
171 | Vertigo (HP:0002321) | 1.82630491 |
172 | Eosinophilia (HP:0001880) | 1.81407473 |
173 | Bicornuate uterus (HP:0000813) | 1.81379280 |
174 | Panhypogammaglobulinemia (HP:0003139) | 1.81329453 |
175 | Abnormality of the pericardium (HP:0001697) | 1.81226923 |
176 | Arterial thrombosis (HP:0004420) | 1.80034219 |
177 | Protruding tongue (HP:0010808) | 1.79721941 |
178 | Hypotension (HP:0002615) | 1.79712031 |
179 | Abnormal tarsal ossification (HP:0008369) | 1.78375912 |
180 | Pulmonary embolism (HP:0002204) | 1.75900133 |
181 | Cystic liver disease (HP:0006706) | 1.75488468 |
182 | Lymphangioma (HP:0100764) | 1.75018867 |
183 | Gingivitis (HP:0000230) | 1.71851300 |
184 | Microcytic anemia (HP:0001935) | 1.71147277 |
185 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.71002541 |
186 | Lethargy (HP:0001254) | 1.70799681 |
187 | Abnormality of the costochondral junction (HP:0000919) | 1.70744557 |
188 | Abnormality of the renal cortex (HP:0011035) | 1.70357625 |
189 | Hyperphosphatemia (HP:0002905) | 1.70122422 |
190 | Sensorimotor neuropathy (HP:0007141) | 1.68147987 |
191 | Abnormality of carpal bone ossification (HP:0006257) | 1.65778816 |
192 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.63978542 |
193 | Generalized muscle weakness (HP:0003324) | 1.62734840 |
194 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.59960712 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WNK4 | 8.80345874 |
2 | WNK3 | 7.25102629 |
3 | OXSR1 | 7.00098261 |
4 | STK39 | 4.41500780 |
5 | TAOK3 | 3.44600341 |
6 | RIPK4 | 3.13979126 |
7 | STK38L | 2.89058781 |
8 | TXK | 2.66215277 |
9 | IRAK4 | 2.62545637 |
10 | BCKDK | 2.46037730 |
11 | ACVR1B | 2.30497216 |
12 | MAP4K1 | 2.14101616 |
13 | ADRBK2 | 2.05882542 |
14 | CSK | 2.02632111 |
15 | FES | 2.00993590 |
16 | WNK1 | 1.91808768 |
17 | BMPR1B | 1.88445389 |
18 | MST4 | 1.80052964 |
19 | IKBKE | 1.69924755 |
20 | SGK494 | 1.68570360 |
21 | SGK223 | 1.68570360 |
22 | MST1R | 1.68551889 |
23 | GRK1 | 1.65214801 |
24 | CAMKK2 | 1.59097993 |
25 | PDK3 | 1.57551733 |
26 | PDK4 | 1.57551733 |
27 | SYK | 1.54502173 |
28 | TLK1 | 1.48828111 |
29 | TYK2 | 1.43620344 |
30 | TNK2 | 1.41168586 |
31 | ZAP70 | 1.35848160 |
32 | PDK2 | 1.34943718 |
33 | HCK | 1.33481695 |
34 | BTK | 1.31377046 |
35 | LYN | 1.31148546 |
36 | KIT | 1.30881350 |
37 | ADRBK1 | 1.28609014 |
38 | EPHB1 | 1.28374028 |
39 | STK38 | 1.22076469 |
40 | MAP3K3 | 1.19512476 |
41 | JAK3 | 1.18038338 |
42 | FGR | 1.15274247 |
43 | IKBKB | 1.15266013 |
44 | MATK | 1.13738350 |
45 | TEC | 1.10416144 |
46 | FGFR4 | 1.08820023 |
47 | TIE1 | 1.08509533 |
48 | MAPK13 | 1.08043225 |
49 | LRRK2 | 1.06772277 |
50 | FER | 1.02003229 |
51 | TGFBR2 | 1.01519431 |
52 | ZAK | 0.99749175 |
53 | SGK2 | 0.99183712 |
54 | JAK1 | 0.98272468 |
55 | SGK3 | 0.97612763 |
56 | INSRR | 0.97240890 |
57 | LCK | 0.96784352 |
58 | SIK2 | 0.93419646 |
59 | ITK | 0.91212816 |
60 | NEK1 | 0.91014407 |
61 | MAP3K14 | 0.89356792 |
62 | LATS1 | 0.88810250 |
63 | MAPK15 | 0.87766820 |
64 | MAP2K4 | 0.85426015 |
65 | GSK3A | 0.84186208 |
66 | MAP3K11 | 0.82765346 |
67 | MAP2K6 | 0.80950941 |
68 | GRK7 | 0.79942179 |
69 | PTK2 | 0.78918688 |
70 | CSF1R | 0.78059073 |
71 | RPS6KA6 | 0.77171686 |
72 | MAP4K2 | 0.76214514 |
73 | ERN1 | 0.75260802 |
74 | NUAK1 | 0.74587850 |
75 | CDK19 | 0.74476579 |
76 | TAOK1 | 0.74059307 |
77 | MAP3K7 | 0.73890197 |
78 | MARK3 | 0.72027532 |
79 | TBK1 | 0.69797741 |
80 | FRK | 0.69249233 |
81 | NLK | 0.68424110 |
82 | MYLK | 0.65828625 |
83 | PINK1 | 0.64367837 |
84 | MAP3K6 | 0.63460934 |
85 | RIPK1 | 0.62198120 |
86 | PAK4 | 0.62046509 |
87 | PIM1 | 0.61091542 |
88 | YES1 | 0.59002299 |
89 | EPHB2 | 0.58447546 |
90 | SGK1 | 0.58355018 |
91 | GRK5 | 0.57759347 |
92 | DYRK1B | 0.52964693 |
93 | ERBB2 | 0.52640451 |
94 | FGFR2 | 0.52363478 |
95 | MET | 0.51416826 |
96 | MARK2 | 0.50061213 |
97 | CAMKK1 | 0.49648600 |
98 | PTK6 | 0.49153953 |
99 | STK24 | 0.48515894 |
100 | PTK2B | 0.48123389 |
101 | PRKAA2 | 0.46591835 |
102 | PRKD2 | 0.44761694 |
103 | FYN | 0.43796063 |
104 | SIK1 | 0.43658506 |
105 | DYRK3 | 0.43655386 |
106 | MAP3K2 | 0.42865189 |
107 | SIK3 | 0.42564307 |
108 | HIPK2 | 0.41412971 |
109 | PRKCI | 0.40663662 |
110 | PDPK1 | 0.40564171 |
111 | GRK6 | 0.40538682 |
112 | STK10 | 0.39254575 |
113 | IRAK3 | 0.38242106 |
114 | PNCK | 0.37481979 |
115 | TNIK | 0.37430303 |
116 | CAMK4 | 0.37151390 |
117 | ABL2 | 0.37031241 |
118 | DYRK2 | 0.36997236 |
119 | RPS6KA5 | 0.35771818 |
120 | PRKAA1 | 0.35008689 |
121 | CASK | 0.34547529 |
122 | DAPK2 | 0.32106022 |
123 | PAK3 | 0.31859848 |
124 | MAP2K3 | 0.31385731 |
125 | EPHA3 | 0.29669639 |
126 | MAPK11 | 0.27375341 |
127 | IRAK1 | 0.26659766 |
128 | PRKCZ | 0.23846977 |
129 | PRKCD | 0.23560935 |
130 | NME1 | 0.23163654 |
131 | EPHA2 | 0.22586836 |
132 | NTRK1 | 0.22197781 |
133 | STK3 | 0.21521166 |
134 | CAMK1G | 0.21328169 |
135 | MAP2K1 | 0.21207499 |
136 | MAP2K2 | 0.17284019 |
137 | INSR | 0.14691921 |
138 | ROCK1 | 0.13967771 |
139 | KDR | 0.13834153 |
140 | BLK | 0.13488921 |
141 | IGF1R | 0.13266891 |
142 | STK11 | 0.12874030 |
143 | EPHA4 | 0.12499044 |
144 | PRKACA | 0.12438903 |
145 | PRKCA | 0.11925059 |
146 | PDK1 | 0.11583820 |
147 | PRKACG | 0.11427363 |
148 | PRKCE | 0.10911944 |
149 | ERBB4 | 0.10833420 |
150 | CAMK1D | 0.10719509 |
151 | TRPM7 | 0.10182696 |
152 | PRKCH | 0.09823399 |
153 | SRC | 0.09699725 |
154 | DDR2 | 0.09178919 |
155 | CHUK | 0.08207114 |
156 | PDGFRB | 0.08067040 |
157 | ABL1 | 0.08032200 |
158 | PIK3CG | 0.07669241 |
159 | FGFR3 | 0.07368489 |
160 | ROCK2 | 0.07316768 |
161 | PRKCQ | 0.07207524 |
162 | JAK2 | 0.07010455 |
163 | TAOK2 | 0.06437757 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butanoate metabolism_Homo sapiens_hsa00650 | 3.56346953 |
2 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 3.54500484 |
3 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.38768630 |
4 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 3.33487330 |
5 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 3.32392345 |
6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.14348969 |
7 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 3.03465576 |
8 | Propanoate metabolism_Homo sapiens_hsa00640 | 3.02479138 |
9 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.71222734 |
10 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.61588846 |
11 | Peroxisome_Homo sapiens_hsa04146 | 2.42113361 |
12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.36653860 |
13 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.27357625 |
14 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.25996460 |
15 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.23043485 |
16 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.21909606 |
17 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.21498415 |
18 | Leishmaniasis_Homo sapiens_hsa05140 | 2.18498395 |
19 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.18086747 |
20 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.12856029 |
21 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.12485469 |
22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.08322876 |
23 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.07277028 |
24 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.06838323 |
25 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.06686270 |
26 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.97224538 |
27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.95554862 |
28 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.92708625 |
29 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.91470361 |
30 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.91369871 |
31 | Allograft rejection_Homo sapiens_hsa05330 | 1.89794827 |
32 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.84336264 |
33 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.80661135 |
34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.77856881 |
35 | Mineral absorption_Homo sapiens_hsa04978 | 1.76699290 |
36 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.63215850 |
37 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.54560469 |
38 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.53506888 |
39 | Nicotine addiction_Homo sapiens_hsa05033 | 1.51907181 |
40 | Bile secretion_Homo sapiens_hsa04976 | 1.50049766 |
41 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.49725202 |
42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.49126686 |
43 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.45310791 |
44 | Tuberculosis_Homo sapiens_hsa05152 | 1.44902679 |
45 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.43504798 |
46 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.41155849 |
47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.40910726 |
48 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.40426267 |
49 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.39258406 |
50 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.38480551 |
51 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.38447570 |
52 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.37747727 |
53 | Other glycan degradation_Homo sapiens_hsa00511 | 1.36575493 |
54 | Malaria_Homo sapiens_hsa05144 | 1.34394560 |
55 | Asthma_Homo sapiens_hsa05310 | 1.33532074 |
56 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.29285638 |
57 | Morphine addiction_Homo sapiens_hsa05032 | 1.27240640 |
58 | Phototransduction_Homo sapiens_hsa04744 | 1.26587001 |
59 | Carbon metabolism_Homo sapiens_hsa01200 | 1.25184265 |
60 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.24615918 |
61 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.24580471 |
62 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.22899962 |
63 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.20910257 |
64 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.19393295 |
65 | Measles_Homo sapiens_hsa05162 | 1.18767161 |
66 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.18388780 |
67 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.18122819 |
68 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.17646131 |
69 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.16341429 |
70 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.15513425 |
71 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.11747876 |
72 | Lysine degradation_Homo sapiens_hsa00310 | 1.11481246 |
73 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.09269802 |
74 | Histidine metabolism_Homo sapiens_hsa00340 | 1.08608399 |
75 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.07563117 |
76 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.07093822 |
77 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.01933344 |
78 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.01384268 |
79 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.00102291 |
80 | Taste transduction_Homo sapiens_hsa04742 | 0.99458642 |
81 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.96107283 |
82 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.94643659 |
83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.92790240 |
84 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.87091607 |
85 | Olfactory transduction_Homo sapiens_hsa04740 | 0.85404971 |
86 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.85250403 |
87 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.84806664 |
88 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.83675555 |
89 | Platelet activation_Homo sapiens_hsa04611 | 0.82460295 |
90 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.82224542 |
91 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.81791372 |
92 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.81174388 |
93 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.80036949 |
94 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.80003657 |
95 | Lysosome_Homo sapiens_hsa04142 | 0.79549700 |
96 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.79351435 |
97 | Legionellosis_Homo sapiens_hsa05134 | 0.76561383 |
98 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.75945257 |
99 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.74050267 |
100 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.72469709 |
101 | Circadian entrainment_Homo sapiens_hsa04713 | 0.72081077 |
102 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.71793295 |
103 | Influenza A_Homo sapiens_hsa05164 | 0.68612166 |
104 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.68449118 |
105 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.68375464 |
106 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.67935047 |
107 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.66860480 |
108 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.66173498 |
109 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.65467712 |
110 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.63270219 |
111 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.62087898 |
112 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.61920072 |
113 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.61403738 |
114 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.61403098 |
115 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.59078478 |
116 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.58893362 |
117 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.58716417 |
118 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.57613547 |
119 | Retinol metabolism_Homo sapiens_hsa00830 | 0.56560887 |
120 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.56345320 |
121 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56132836 |
122 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.55896996 |
123 | GABAergic synapse_Homo sapiens_hsa04727 | 0.54467904 |
124 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.54202237 |
125 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.51858660 |
126 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.51706416 |
127 | * Gastric acid secretion_Homo sapiens_hsa04971 | 0.50610814 |
128 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.49986951 |
129 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.49659170 |
130 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.49257950 |
131 | Long-term depression_Homo sapiens_hsa04730 | 0.49008962 |
132 | Salivary secretion_Homo sapiens_hsa04970 | 0.47801814 |
133 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.45304685 |
134 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.44981740 |
135 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.44714225 |
136 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.44619524 |
137 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.44466546 |
138 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.44296733 |
139 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44213869 |
140 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.43527777 |
141 | Pertussis_Homo sapiens_hsa05133 | 0.43264914 |
142 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.42917830 |
143 | Viral myocarditis_Homo sapiens_hsa05416 | 0.40991289 |
144 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.40368193 |
145 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.40177376 |
146 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.33214101 |
147 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.33179879 |
148 | ABC transporters_Homo sapiens_hsa02010 | 0.33048351 |
149 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.31644453 |
150 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.31518690 |
151 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.28295941 |
152 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.27933200 |
153 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.25499782 |
154 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.24154216 |
155 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.21117035 |
156 | Sulfur relay system_Homo sapiens_hsa04122 | 0.18297016 |
157 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.17118722 |
158 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.15584355 |
159 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.15000583 |
160 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.13122741 |
161 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.12459470 |
162 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.11968672 |
163 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.11578485 |
164 | Phagosome_Homo sapiens_hsa04145 | 0.10501536 |
165 | Insulin resistance_Homo sapiens_hsa04931 | 0.10495360 |
166 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.09526106 |
167 | Focal adhesion_Homo sapiens_hsa04510 | 0.08043290 |
168 | Bladder cancer_Homo sapiens_hsa05219 | 0.07740620 |
169 | Hepatitis C_Homo sapiens_hsa05160 | 0.07648678 |
170 | Tight junction_Homo sapiens_hsa04530 | 0.06906986 |
171 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.06662813 |
172 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.04086637 |
173 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.03960277 |
174 | Parkinsons disease_Homo sapiens_hsa05012 | 0.00371491 |
175 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.00061622 |