Rank | Gene Set | Z-score |
---|---|---|
1 | presynaptic membrane assembly (GO:0097105) | 5.89289888 |
2 | presynaptic membrane organization (GO:0097090) | 5.15956004 |
3 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.90380890 |
4 | central nervous system myelination (GO:0022010) | 4.77244517 |
5 | axon ensheathment in central nervous system (GO:0032291) | 4.77244517 |
6 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.72395884 |
7 | locomotory exploration behavior (GO:0035641) | 4.69149230 |
8 | synaptic vesicle maturation (GO:0016188) | 4.46944787 |
9 | synaptic vesicle exocytosis (GO:0016079) | 4.36570579 |
10 | vocalization behavior (GO:0071625) | 4.06777780 |
11 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.96209047 |
12 | neuron cell-cell adhesion (GO:0007158) | 3.95292427 |
13 | establishment of nucleus localization (GO:0040023) | 3.91396250 |
14 | regulation of synapse structural plasticity (GO:0051823) | 3.90660281 |
15 | glutamate secretion (GO:0014047) | 3.85948404 |
16 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.84935249 |
17 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.84073724 |
18 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.83518303 |
19 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.75990307 |
20 | regulation of neurotransmitter uptake (GO:0051580) | 3.74400370 |
21 | proline transport (GO:0015824) | 3.70203968 |
22 | prepulse inhibition (GO:0060134) | 3.69247247 |
23 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.69155363 |
24 | neurotransmitter secretion (GO:0007269) | 3.68743645 |
25 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.62538866 |
26 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.62262572 |
27 | L-amino acid import (GO:0043092) | 3.59474213 |
28 | C4-dicarboxylate transport (GO:0015740) | 3.58992041 |
29 | exploration behavior (GO:0035640) | 3.57917338 |
30 | response to auditory stimulus (GO:0010996) | 3.57388475 |
31 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.56952149 |
32 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.48018405 |
33 | behavioral response to nicotine (GO:0035095) | 3.47024385 |
34 | cellular potassium ion homeostasis (GO:0030007) | 3.46407902 |
35 | auditory behavior (GO:0031223) | 3.42861926 |
36 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.39579315 |
37 | regulation of synaptic vesicle transport (GO:1902803) | 3.36741777 |
38 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 3.36722460 |
39 | gamma-aminobutyric acid transport (GO:0015812) | 3.36664319 |
40 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.35809435 |
41 | neurotransmitter uptake (GO:0001504) | 3.35286542 |
42 | alanine transport (GO:0032328) | 3.32216397 |
43 | myelination in peripheral nervous system (GO:0022011) | 3.31648419 |
44 | peripheral nervous system axon ensheathment (GO:0032292) | 3.31648419 |
45 | layer formation in cerebral cortex (GO:0021819) | 3.27514106 |
46 | astrocyte development (GO:0014002) | 3.27400296 |
47 | cellular sodium ion homeostasis (GO:0006883) | 3.27229832 |
48 | innervation (GO:0060384) | 3.26844451 |
49 | cellular response to nerve growth factor stimulus (GO:1990090) | 3.25194198 |
50 | response to nerve growth factor (GO:1990089) | 3.25194198 |
51 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.23935582 |
52 | response to histamine (GO:0034776) | 3.22924187 |
53 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.19970155 |
54 | sodium ion export (GO:0071436) | 3.19930132 |
55 | activation of protein kinase A activity (GO:0034199) | 3.18930480 |
56 | neurotransmitter transport (GO:0006836) | 3.18489051 |
57 | transmission of nerve impulse (GO:0019226) | 3.18290291 |
58 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.17762446 |
59 | dendritic spine morphogenesis (GO:0060997) | 3.17152251 |
60 | neuronal action potential propagation (GO:0019227) | 3.17121777 |
61 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.16280020 |
62 | somite development (GO:0061053) | 3.13907175 |
63 | tongue development (GO:0043586) | 3.12785717 |
64 | glutamate receptor signaling pathway (GO:0007215) | 3.11913960 |
65 | synaptic transmission, glutamatergic (GO:0035249) | 3.11107602 |
66 | cell communication by electrical coupling (GO:0010644) | 3.09228036 |
67 | long-term memory (GO:0007616) | 3.08588166 |
68 | regulation of neurotransmitter levels (GO:0001505) | 3.08543911 |
69 | protein localization to synapse (GO:0035418) | 3.08251861 |
70 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.07802628 |
71 | photoreceptor cell differentiation (GO:0046530) | 3.07692025 |
72 | eye photoreceptor cell differentiation (GO:0001754) | 3.07692025 |
73 | neuron-neuron synaptic transmission (GO:0007270) | 3.07465025 |
74 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 3.07193710 |
75 | astrocyte differentiation (GO:0048708) | 3.07066160 |
76 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.06384955 |
77 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.05059624 |
78 | potassium ion homeostasis (GO:0055075) | 3.03230711 |
79 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 3.02397041 |
80 | regulation of vesicle fusion (GO:0031338) | 3.02128986 |
81 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.01890724 |
82 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 3.00606784 |
83 | regulation of heat generation (GO:0031650) | 3.00571117 |
84 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 2.98379479 |
85 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.97163113 |
86 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.96953157 |
87 | striatum development (GO:0021756) | 2.96458614 |
88 | mating behavior (GO:0007617) | 2.95269339 |
89 | postsynaptic membrane organization (GO:0001941) | 2.93780098 |
90 | dendrite morphogenesis (GO:0048813) | 2.92611258 |
91 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.92521733 |
92 | phenol-containing compound catabolic process (GO:0019336) | 2.91299614 |
93 | dermatan sulfate biosynthetic process (GO:0030208) | 2.90336231 |
94 | catecholamine transport (GO:0051937) | 2.87284667 |
95 | cAMP-mediated signaling (GO:0019933) | 2.86851950 |
96 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.86724050 |
97 | detection of calcium ion (GO:0005513) | 2.86102774 |
98 | positive regulation of synapse assembly (GO:0051965) | 2.85380300 |
99 | dopamine transport (GO:0015872) | 2.84930869 |
100 | membrane assembly (GO:0071709) | 2.84787354 |
101 | regulation of membrane repolarization (GO:0060306) | 2.84760729 |
102 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.84528451 |
103 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.83767064 |
104 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.82272428 |
105 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.80708783 |
106 | axonal fasciculation (GO:0007413) | 2.80191043 |
107 | neuronal ion channel clustering (GO:0045161) | 2.79206048 |
108 | response to inactivity (GO:0014854) | 2.78892551 |
109 | cerebellar Purkinje cell layer development (GO:0021680) | 2.78059875 |
110 | suckling behavior (GO:0001967) | 2.77458180 |
111 | potassium ion import (GO:0010107) | 2.77185378 |
112 | nucleus localization (GO:0051647) | 2.75790536 |
113 | neuromuscular process controlling posture (GO:0050884) | 2.75725592 |
114 | regulation of postsynaptic membrane potential (GO:0060078) | 2.75305006 |
115 | negative regulation of nucleotide biosynthetic process (GO:0030809) | 2.75068099 |
116 | negative regulation of purine nucleotide biosynthetic process (GO:1900372) | 2.75068099 |
117 | neuron recognition (GO:0008038) | 2.74737924 |
118 | long-term synaptic potentiation (GO:0060291) | 2.74438957 |
119 | synaptic vesicle endocytosis (GO:0048488) | 2.73567641 |
120 | amino acid import (GO:0043090) | 2.73545753 |
121 | insulin secretion (GO:0030073) | 2.73498126 |
122 | adult walking behavior (GO:0007628) | 2.73370122 |
123 | neuromuscular process controlling balance (GO:0050885) | 2.73038813 |
124 | positive regulation of potassium ion transport (GO:0043268) | 2.72194607 |
125 | establishment of mitochondrion localization (GO:0051654) | 2.72107753 |
126 | nonmotile primary cilium assembly (GO:0035058) | 2.71320318 |
127 | cyclic-nucleotide-mediated signaling (GO:0019935) | 2.71103908 |
128 | regulation of synaptic plasticity (GO:0048167) | 2.70980491 |
129 | synapse assembly (GO:0007416) | 2.70320131 |
130 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 2.69871492 |
131 | acidic amino acid transport (GO:0015800) | 2.69696276 |
132 | regulation of ARF protein signal transduction (GO:0032012) | 2.69630566 |
133 | synaptic transmission, dopaminergic (GO:0001963) | 2.69432669 |
134 | regulation of respiratory system process (GO:0044065) | 2.68662534 |
135 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.68447978 |
136 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.68377392 |
137 | membrane depolarization during action potential (GO:0086010) | 2.67873398 |
138 | cellular response to cholesterol (GO:0071397) | 2.67413189 |
139 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.67222872 |
140 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.67222872 |
141 | regulation of potassium ion transmembrane transporter activity (GO:1901016) | 2.66919165 |
142 | positive regulation of vesicle fusion (GO:0031340) | 2.66203775 |
143 | neurotransmitter catabolic process (GO:0042135) | 2.66064331 |
144 | positive regulation of membrane potential (GO:0045838) | 2.65576292 |
145 | synaptic transmission, cholinergic (GO:0007271) | 2.65573399 |
146 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.65333181 |
147 | negative regulation of astrocyte differentiation (GO:0048712) | 2.64999006 |
148 | serotonin metabolic process (GO:0042428) | 2.64658304 |
149 | vesicle transport along microtubule (GO:0047496) | 2.64442567 |
150 | dopamine biosynthetic process (GO:0042416) | 2.63030428 |
151 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.62989914 |
152 | negative regulation of neurotransmitter transport (GO:0051589) | 2.62674771 |
153 | behavioral response to cocaine (GO:0048148) | 2.61063910 |
154 | regulation of dopamine metabolic process (GO:0042053) | 2.60750422 |
155 | regulation of catecholamine metabolic process (GO:0042069) | 2.60750422 |
156 | mechanosensory behavior (GO:0007638) | 2.60616390 |
157 | regulation of neurotransmitter transport (GO:0051588) | 2.58959684 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.96242599 |
2 | * GBX2_23144817_ChIP-Seq_PC3_Human | 3.08575608 |
3 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.93997563 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.89865602 |
5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.64225813 |
6 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.51959557 |
7 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.44168613 |
8 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.42627548 |
9 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.41668812 |
10 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.40482402 |
11 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.39300644 |
12 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.38465923 |
13 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.38465923 |
14 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.37013238 |
15 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.36902465 |
16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.31777014 |
17 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.31655614 |
18 | * RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.14479687 |
19 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.08975323 |
20 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.06545780 |
21 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.03683967 |
22 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.01912337 |
23 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.99541575 |
24 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.97962418 |
25 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.84852655 |
26 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.82063240 |
27 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.78404363 |
28 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.73820891 |
29 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.73420669 |
30 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.66469604 |
31 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.64636799 |
32 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.63733020 |
33 | VDR_22108803_ChIP-Seq_LS180_Human | 1.60955278 |
34 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.59903871 |
35 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.56623689 |
36 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.53109241 |
37 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.52774260 |
38 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.50898514 |
39 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.50231253 |
40 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.49016292 |
41 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.47807095 |
42 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.46553721 |
43 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.43732680 |
44 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.43262118 |
45 | * CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.40686102 |
46 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.40148610 |
47 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.35835607 |
48 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.33962212 |
49 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.33687855 |
50 | P300_19829295_ChIP-Seq_ESCs_Human | 1.33541899 |
51 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.33231432 |
52 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.32857752 |
53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.30952388 |
54 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.30850360 |
55 | * MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.30723593 |
56 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.30549580 |
57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.29949240 |
58 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.28649131 |
59 | STAT3_23295773_ChIP-Seq_U87_Human | 1.28566527 |
60 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.28373115 |
61 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.28347611 |
62 | AR_19668381_ChIP-Seq_PC3_Human | 1.26481232 |
63 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25981097 |
64 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.25183457 |
65 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25183457 |
66 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.24503753 |
67 | AR_25329375_ChIP-Seq_VCAP_Human | 1.22213884 |
68 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.21940103 |
69 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.21748512 |
70 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.21658708 |
71 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.19466264 |
72 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.19465729 |
73 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.19087942 |
74 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.17504199 |
75 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.17255615 |
76 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.17126549 |
77 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.16512085 |
78 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.16377284 |
79 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.16240690 |
80 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.14532726 |
81 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.14330966 |
82 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.14051432 |
83 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.13997141 |
84 | * KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.13829007 |
85 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.13009497 |
86 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.12847784 |
87 | * TP53_16413492_ChIP-PET_HCT116_Human | 1.12832446 |
88 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.11810217 |
89 | * NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.11523723 |
90 | TCF4_23295773_ChIP-Seq_U87_Human | 1.10425600 |
91 | * CBP_20019798_ChIP-Seq_JUKART_Human | 1.10375491 |
92 | * IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.10375491 |
93 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07645704 |
94 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.06823576 |
95 | RXR_22108803_ChIP-Seq_LS180_Human | 1.05315552 |
96 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.04863136 |
97 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 1.04195543 |
98 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.04169164 |
99 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.03588319 |
100 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.03357694 |
101 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 1.02913991 |
102 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.02061086 |
103 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.00957757 |
104 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.00725250 |
105 | * EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.00718650 |
106 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.00439977 |
107 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 0.99931914 |
108 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.99421464 |
109 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 0.98813706 |
110 | * SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.96930339 |
111 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.96758673 |
112 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.96707891 |
113 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.96690507 |
114 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.96540233 |
115 | * DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.96332329 |
116 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95151067 |
117 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.95014322 |
118 | KDM2B_26808549_Chip-Seq_K562_Human | 0.92662436 |
119 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.92030064 |
120 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.90302905 |
121 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.90155698 |
122 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89666044 |
123 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.89525483 |
124 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.87758048 |
125 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.86928404 |
126 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.86798015 |
127 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.86324987 |
128 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.85643676 |
129 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.83904464 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 4.92177541 |
2 | MP0003635_abnormal_synaptic_transmissio | 3.56034582 |
3 | MP0003880_abnormal_central_pattern | 3.50967548 |
4 | MP0004270_analgesia | 3.44259885 |
5 | MP0002822_catalepsy | 3.13845701 |
6 | MP0003136_yellow_coat_color | 2.99376662 |
7 | MP0002909_abnormal_adrenal_gland | 2.93594847 |
8 | MP0009745_abnormal_behavioral_response | 2.84732806 |
9 | MP0009046_muscle_twitch | 2.77042516 |
10 | MP0002063_abnormal_learning/memory/cond | 2.69038354 |
11 | MP0002064_seizures | 2.64076476 |
12 | MP0009780_abnormal_chondrocyte_physiolo | 2.63193386 |
13 | MP0002653_abnormal_ependyma_morphology | 2.54706486 |
14 | MP0002572_abnormal_emotion/affect_behav | 2.51280007 |
15 | MP0001501_abnormal_sleep_pattern | 2.41676604 |
16 | MP0005423_abnormal_somatic_nervous | 2.41588905 |
17 | MP0001486_abnormal_startle_reflex | 2.30339570 |
18 | MP0005646_abnormal_pituitary_gland | 2.21876450 |
19 | MP0002734_abnormal_mechanical_nocicepti | 2.20560210 |
20 | MP0003122_maternal_imprinting | 2.09402528 |
21 | MP0002272_abnormal_nervous_system | 2.05140406 |
22 | MP0005645_abnormal_hypothalamus_physiol | 2.04505372 |
23 | MP0001968_abnormal_touch/_nociception | 2.02234653 |
24 | MP0000013_abnormal_adipose_tissue | 2.01813375 |
25 | MP0004858_abnormal_nervous_system | 1.89689127 |
26 | MP0002733_abnormal_thermal_nociception | 1.89243525 |
27 | MP0001529_abnormal_vocalization | 1.85781552 |
28 | MP0006276_abnormal_autonomic_nervous | 1.80927431 |
29 | MP0002557_abnormal_social/conspecific_i | 1.77708546 |
30 | MP0001502_abnormal_circadian_rhythm | 1.76632012 |
31 | MP0005386_behavior/neurological_phenoty | 1.75641585 |
32 | MP0004924_abnormal_behavior | 1.75641585 |
33 | MP0001440_abnormal_grooming_behavior | 1.67460289 |
34 | MP0001970_abnormal_pain_threshold | 1.65427027 |
35 | MP0003283_abnormal_digestive_organ | 1.64487362 |
36 | MP0004885_abnormal_endolymph | 1.61773806 |
37 | MP0001905_abnormal_dopamine_level | 1.60374935 |
38 | MP0002067_abnormal_sensory_capabilities | 1.58893222 |
39 | MP0008569_lethality_at_weaning | 1.55309022 |
40 | MP0003183_abnormal_peptide_metabolism | 1.43096130 |
41 | MP0002184_abnormal_innervation | 1.41565954 |
42 | MP0003329_amyloid_beta_deposits | 1.40863954 |
43 | MP0002736_abnormal_nociception_after | 1.40393959 |
44 | MP0000955_abnormal_spinal_cord | 1.40193568 |
45 | MP0010386_abnormal_urinary_bladder | 1.39253596 |
46 | MP0000569_abnormal_digit_pigmentation | 1.38518209 |
47 | MP0000778_abnormal_nervous_system | 1.35998751 |
48 | MP0008961_abnormal_basal_metabolism | 1.35797110 |
49 | MP0004811_abnormal_neuron_physiology | 1.34763832 |
50 | MP0001984_abnormal_olfaction | 1.33887260 |
51 | MP0003633_abnormal_nervous_system | 1.33432917 |
52 | MP0001299_abnormal_eye_distance/ | 1.31045747 |
53 | MP0005253_abnormal_eye_physiology | 1.30751973 |
54 | MP0000026_abnormal_inner_ear | 1.29916302 |
55 | MP0005379_endocrine/exocrine_gland_phen | 1.29354914 |
56 | MP0003787_abnormal_imprinting | 1.28675591 |
57 | MP0000751_myopathy | 1.27920783 |
58 | MP0005171_absent_coat_pigmentation | 1.27622156 |
59 | MP0003690_abnormal_glial_cell | 1.26606442 |
60 | MP0005167_abnormal_blood-brain_barrier | 1.22801817 |
61 | MP0001963_abnormal_hearing_physiology | 1.21063484 |
62 | MP0002638_abnormal_pupillary_reflex | 1.20926055 |
63 | MP0002066_abnormal_motor_capabilities/c | 1.20648436 |
64 | MP0002882_abnormal_neuron_morphology | 1.20124623 |
65 | MP0000920_abnormal_myelination | 1.16490561 |
66 | MP0004145_abnormal_muscle_electrophysio | 1.16184676 |
67 | MP0002837_dystrophic_cardiac_calcinosis | 1.14782751 |
68 | MP0002735_abnormal_chemical_nociception | 1.14383393 |
69 | MP0000631_abnormal_neuroendocrine_gland | 1.10752957 |
70 | MP0001986_abnormal_taste_sensitivity | 1.07183847 |
71 | MP0002752_abnormal_somatic_nervous | 1.07032679 |
72 | MP0004043_abnormal_pH_regulation | 1.06798899 |
73 | MP0004742_abnormal_vestibular_system | 1.06761637 |
74 | MP0005535_abnormal_body_temperature | 1.06654129 |
75 | MP0003631_nervous_system_phenotype | 1.06552845 |
76 | MP0003634_abnormal_glial_cell | 1.05615745 |
77 | MP0001188_hyperpigmentation | 1.04593090 |
78 | MP0000049_abnormal_middle_ear | 1.00998452 |
79 | MP0003879_abnormal_hair_cell | 0.97804411 |
80 | MP0003172_abnormal_lysosome_physiology | 0.97366771 |
81 | MP0002090_abnormal_vision | 0.95694412 |
82 | MP0002751_abnormal_autonomic_nervous | 0.95630569 |
83 | MP0002152_abnormal_brain_morphology | 0.92862011 |
84 | MP0005248_abnormal_Harderian_gland | 0.92822227 |
85 | MP0000749_muscle_degeneration | 0.89853258 |
86 | MP0002069_abnormal_eating/drinking_beha | 0.89091091 |
87 | MP0003646_muscle_fatigue | 0.88982465 |
88 | MP0004085_abnormal_heartbeat | 0.87696303 |
89 | MP0003075_altered_response_to | 0.86918710 |
90 | MP0002233_abnormal_nose_morphology | 0.86304631 |
91 | MP0003938_abnormal_ear_development | 0.86202185 |
92 | MP0002693_abnormal_pancreas_physiology | 0.85681723 |
93 | MP0005394_taste/olfaction_phenotype | 0.85360103 |
94 | MP0005499_abnormal_olfactory_system | 0.85360103 |
95 | MP0003861_abnormal_nervous_system | 0.83631305 |
96 | MP0001944_abnormal_pancreas_morphology | 0.82037117 |
97 | MP0003632_abnormal_nervous_system | 0.81155451 |
98 | MP0001664_abnormal_digestion | 0.79325307 |
99 | MP0001177_atelectasis | 0.79030716 |
100 | MP0002229_neurodegeneration | 0.78929241 |
101 | MP0006072_abnormal_retinal_apoptosis | 0.77993437 |
102 | MP0004142_abnormal_muscle_tone | 0.76799731 |
103 | MP0002249_abnormal_larynx_morphology | 0.76195447 |
104 | MP0005187_abnormal_penis_morphology | 0.74267379 |
105 | MP0000003_abnormal_adipose_tissue | 0.72293837 |
106 | MP0002254_reproductive_system_inflammat | 0.72258588 |
107 | MP0008872_abnormal_physiological_respon | 0.71828008 |
108 | MP0008789_abnormal_olfactory_epithelium | 0.71017422 |
109 | MP0002234_abnormal_pharynx_morphology | 0.70011185 |
110 | MP0004130_abnormal_muscle_cell | 0.69959280 |
111 | MP0004215_abnormal_myocardial_fiber | 0.69370819 |
112 | MP0002102_abnormal_ear_morphology | 0.68575897 |
113 | MP0005620_abnormal_muscle_contractility | 0.67834134 |
114 | MP0000613_abnormal_salivary_gland | 0.67170989 |
115 | MP0003045_fibrosis | 0.66905950 |
116 | MP0008874_decreased_physiological_sensi | 0.66483617 |
117 | MP0006292_abnormal_olfactory_placode | 0.66167774 |
118 | MP0000534_abnormal_ureter_morphology | 0.65442813 |
119 | MP0005551_abnormal_eye_electrophysiolog | 0.65031844 |
120 | MP0003137_abnormal_impulse_conducting | 0.64208343 |
121 | * MP0001943_abnormal_respiration | 0.63819204 |
122 | MP0002095_abnormal_skin_pigmentation | 0.63585068 |
123 | MP0001270_distended_abdomen | 0.63000475 |
124 | MP0005409_darkened_coat_color | 0.62986569 |
125 | MP0002078_abnormal_glucose_homeostasis | 0.62725411 |
126 | MP0001485_abnormal_pinna_reflex | 0.61779512 |
127 | MP0000747_muscle_weakness | 0.61341927 |
128 | MP0002108_abnormal_muscle_morphology | 0.58501285 |
129 | MP0005623_abnormal_meninges_morphology | 0.58362703 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 5.43876249 |
2 | Myokymia (HP:0002411) | 4.67978587 |
3 | Visual hallucinations (HP:0002367) | 4.33262565 |
4 | Focal seizures (HP:0007359) | 4.30132862 |
5 | Limb dystonia (HP:0002451) | 3.81831434 |
6 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 3.61783047 |
7 | Supranuclear gaze palsy (HP:0000605) | 3.60230754 |
8 | Action tremor (HP:0002345) | 3.52633769 |
9 | Neurofibrillary tangles (HP:0002185) | 3.49714108 |
10 | Epileptic encephalopathy (HP:0200134) | 3.36795255 |
11 | Cerebral inclusion bodies (HP:0100314) | 3.34408475 |
12 | Megalencephaly (HP:0001355) | 3.27042829 |
13 | Progressive cerebellar ataxia (HP:0002073) | 3.24811201 |
14 | Aplasia involving bones of the extremities (HP:0009825) | 3.09600831 |
15 | Aplasia involving bones of the upper limbs (HP:0009823) | 3.09600831 |
16 | Aplasia of the phalanges of the hand (HP:0009802) | 3.09600831 |
17 | Generalized tonic-clonic seizures (HP:0002069) | 3.07203596 |
18 | Papilledema (HP:0001085) | 3.01281480 |
19 | Pheochromocytoma (HP:0002666) | 2.92235867 |
20 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.89408714 |
21 | Abnormality of the labia minora (HP:0012880) | 2.88453311 |
22 | Anxiety (HP:0000739) | 2.88150885 |
23 | Depression (HP:0000716) | 2.87717775 |
24 | Fetal akinesia sequence (HP:0001989) | 2.86891082 |
25 | Absent/shortened dynein arms (HP:0200106) | 2.80498878 |
26 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.80498878 |
27 | Abnormality of the diencephalon (HP:0010662) | 2.78259067 |
28 | Postural instability (HP:0002172) | 2.73201608 |
29 | Inability to walk (HP:0002540) | 2.72598663 |
30 | Absence seizures (HP:0002121) | 2.68841836 |
31 | Hemiparesis (HP:0001269) | 2.65817078 |
32 | Agitation (HP:0000713) | 2.65169499 |
33 | True hermaphroditism (HP:0010459) | 2.63865249 |
34 | Ankle clonus (HP:0011448) | 2.58466618 |
35 | Pancreatic fibrosis (HP:0100732) | 2.58193914 |
36 | Gait imbalance (HP:0002141) | 2.56550873 |
37 | Increased circulating renin level (HP:0000848) | 2.56279150 |
38 | Truncal ataxia (HP:0002078) | 2.52452603 |
39 | Split foot (HP:0001839) | 2.52380019 |
40 | Atonic seizures (HP:0010819) | 2.49264782 |
41 | Dialeptic seizures (HP:0011146) | 2.48619047 |
42 | Dysdiadochokinesis (HP:0002075) | 2.48149739 |
43 | EEG with generalized epileptiform discharges (HP:0011198) | 2.47530998 |
44 | Abnormality of the ischium (HP:0003174) | 2.46863937 |
45 | Epileptiform EEG discharges (HP:0011182) | 2.45418354 |
46 | Febrile seizures (HP:0002373) | 2.45006761 |
47 | Conical tooth (HP:0000698) | 2.44897911 |
48 | Abnormality of midbrain morphology (HP:0002418) | 2.42545662 |
49 | Molar tooth sign on MRI (HP:0002419) | 2.42545662 |
50 | Hypsarrhythmia (HP:0002521) | 2.40885338 |
51 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.40281661 |
52 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.40281661 |
53 | Long nose (HP:0003189) | 2.39022630 |
54 | Neoplasm of the oral cavity (HP:0100649) | 2.37237354 |
55 | Neuroendocrine neoplasm (HP:0100634) | 2.36364276 |
56 | Abnormal eating behavior (HP:0100738) | 2.34889018 |
57 | Abnormality of the 4th metacarpal (HP:0010012) | 2.34633039 |
58 | Abnormality of binocular vision (HP:0011514) | 2.33156374 |
59 | Diplopia (HP:0000651) | 2.33156374 |
60 | Hypoventilation (HP:0002791) | 2.33135103 |
61 | Medial flaring of the eyebrow (HP:0010747) | 2.32810866 |
62 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.30322780 |
63 | Bilateral microphthalmos (HP:0007633) | 2.27695248 |
64 | Akinesia (HP:0002304) | 2.27212276 |
65 | Absent speech (HP:0001344) | 2.26736827 |
66 | Pancreatic cysts (HP:0001737) | 2.26506451 |
67 | Failure to thrive in infancy (HP:0001531) | 2.25128128 |
68 | Type II lissencephaly (HP:0007260) | 2.23893578 |
69 | Lissencephaly (HP:0001339) | 2.22977913 |
70 | Postural tremor (HP:0002174) | 2.22212067 |
71 | Impaired smooth pursuit (HP:0007772) | 2.21911150 |
72 | Excessive salivation (HP:0003781) | 2.21515269 |
73 | Drooling (HP:0002307) | 2.21515269 |
74 | Abnormal pancreas size (HP:0012094) | 2.21251852 |
75 | Short 4th metacarpal (HP:0010044) | 2.20045715 |
76 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.20045715 |
77 | Broad-based gait (HP:0002136) | 2.19659971 |
78 | Bronchomalacia (HP:0002780) | 2.19439688 |
79 | Annular pancreas (HP:0001734) | 2.18024067 |
80 | Macroorchidism (HP:0000053) | 2.17467480 |
81 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.17181208 |
82 | Prolonged QT interval (HP:0001657) | 2.16838102 |
83 | Torticollis (HP:0000473) | 2.16161163 |
84 | Hemiplegia (HP:0002301) | 2.15267684 |
85 | Poor eye contact (HP:0000817) | 2.15105628 |
86 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.14275233 |
87 | Pachygyria (HP:0001302) | 2.12980360 |
88 | Myotonia (HP:0002486) | 2.12328650 |
89 | Oligodactyly (hands) (HP:0001180) | 2.12322290 |
90 | Abnormality of the corticospinal tract (HP:0002492) | 2.11787629 |
91 | Bradykinesia (HP:0002067) | 2.10751322 |
92 | Dysmetria (HP:0001310) | 2.10360304 |
93 | Genetic anticipation (HP:0003743) | 2.08588082 |
94 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.05397260 |
95 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.05170451 |
96 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.04949614 |
97 | Impaired social interactions (HP:0000735) | 2.04457783 |
98 | Abnormal social behavior (HP:0012433) | 2.04457783 |
99 | Hypokalemic alkalosis (HP:0001949) | 2.04264772 |
100 | Rigidity (HP:0002063) | 2.03745314 |
101 | Congenital primary aphakia (HP:0007707) | 2.02789225 |
102 | Hypoplastic ischia (HP:0003175) | 2.02615491 |
103 | Hypothermia (HP:0002045) | 2.01343568 |
104 | Nephrogenic diabetes insipidus (HP:0009806) | 2.00525534 |
105 | Hypercortisolism (HP:0001578) | 2.00221543 |
106 | Protruding tongue (HP:0010808) | 2.00044829 |
107 | Hepatoblastoma (HP:0002884) | 1.98333900 |
108 | Intention tremor (HP:0002080) | 1.97603053 |
109 | Clumsiness (HP:0002312) | 1.97207573 |
110 | Stereotypic behavior (HP:0000733) | 1.96796351 |
111 | Rapidly progressive (HP:0003678) | 1.96555501 |
112 | Neoplasm of the heart (HP:0100544) | 1.94760554 |
113 | Nephronophthisis (HP:0000090) | 1.94611400 |
114 | Anophthalmia (HP:0000528) | 1.93429442 |
115 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.93086594 |
116 | Hyperventilation (HP:0002883) | 1.88840396 |
117 | Hypoglycemic seizures (HP:0002173) | 1.88670717 |
118 | Chronic hepatic failure (HP:0100626) | 1.88298838 |
119 | Resting tremor (HP:0002322) | 1.88042399 |
120 | Retinal dysplasia (HP:0007973) | 1.87590673 |
121 | Abnormal EKG (HP:0003115) | 1.87056749 |
122 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.86147331 |
123 | Lower limb muscle weakness (HP:0007340) | 1.84711515 |
124 | Genital tract atresia (HP:0001827) | 1.83697182 |
125 | Polyphagia (HP:0002591) | 1.83052237 |
126 | Metabolic alkalosis (HP:0200114) | 1.81710469 |
127 | Gaze-evoked nystagmus (HP:0000640) | 1.81411965 |
128 | Cutaneous finger syndactyly (HP:0010554) | 1.81277001 |
129 | Psychosis (HP:0000709) | 1.81123028 |
130 | Mutism (HP:0002300) | 1.80673571 |
131 | Exercise-induced muscle cramps (HP:0003710) | 1.78745009 |
132 | Neuronal loss in central nervous system (HP:0002529) | 1.78592681 |
133 | Vaginal atresia (HP:0000148) | 1.78264900 |
134 | Focal dystonia (HP:0004373) | 1.78164308 |
135 | Ventricular fibrillation (HP:0001663) | 1.76509045 |
136 | Retinal atrophy (HP:0001105) | 1.76492402 |
137 | Oligodactyly (HP:0012165) | 1.76183724 |
138 | Spastic tetraparesis (HP:0001285) | 1.75983871 |
139 | Exercise-induced myalgia (HP:0003738) | 1.74951264 |
140 | Progressive inability to walk (HP:0002505) | 1.74676625 |
141 | Renal hypoplasia (HP:0000089) | 1.74648799 |
142 | Peripheral hypomyelination (HP:0007182) | 1.74430082 |
143 | Amblyopia (HP:0000646) | 1.74152797 |
144 | Morphological abnormality of the inner ear (HP:0011390) | 1.71976987 |
145 | Lower limb amyotrophy (HP:0007210) | 1.71337294 |
146 | Urinary urgency (HP:0000012) | 1.70484751 |
147 | Specific learning disability (HP:0001328) | 1.69068104 |
148 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.68163756 |
149 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.68163756 |
150 | Dysostosis multiplex (HP:0000943) | 1.67772350 |
151 | Large for gestational age (HP:0001520) | 1.66894796 |
152 | Open mouth (HP:0000194) | 1.65274645 |
153 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.65203667 |
154 | Symptomatic seizures (HP:0011145) | 1.64068811 |
155 | Potter facies (HP:0002009) | 1.63911364 |
156 | Facial shape deformation (HP:0011334) | 1.63911364 |
157 | Blue irides (HP:0000635) | 1.63801813 |
158 | Spastic gait (HP:0002064) | 1.63618833 |
159 | Abnormal ciliary motility (HP:0012262) | 1.63088501 |
160 | Hyperparathyroidism (HP:0000843) | 1.62771434 |
161 | Craniofacial dystonia (HP:0012179) | 1.62440881 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.21751549 |
2 | EPHA4 | 3.70338711 |
3 | MAP3K9 | 3.08391910 |
4 | NTRK2 | 2.79404245 |
5 | PRKD3 | 2.58168548 |
6 | PINK1 | 2.43189080 |
7 | NTRK1 | 2.40466708 |
8 | MARK1 | 2.37898881 |
9 | INSRR | 2.33224685 |
10 | MAP3K4 | 2.33085594 |
11 | OBSCN | 2.19591242 |
12 | DAPK2 | 2.03994409 |
13 | MINK1 | 2.01714509 |
14 | TAOK3 | 2.00371987 |
15 | KSR2 | 1.93659580 |
16 | BCR | 1.87696664 |
17 | BMPR1B | 1.75516372 |
18 | TNIK | 1.72287771 |
19 | PKN1 | 1.69950681 |
20 | PAK6 | 1.67508070 |
21 | MAP2K7 | 1.66304175 |
22 | MAP3K2 | 1.58481042 |
23 | CAMKK1 | 1.56501374 |
24 | PHKG1 | 1.48626281 |
25 | PHKG2 | 1.48626281 |
26 | GRK5 | 1.46381958 |
27 | CDK5 | 1.45877725 |
28 | MAP2K4 | 1.42714896 |
29 | MAP3K12 | 1.36499201 |
30 | RIPK4 | 1.35583155 |
31 | EPHA3 | 1.33862729 |
32 | LMTK2 | 1.32295989 |
33 | CDK3 | 1.31948184 |
34 | PRKCH | 1.31833327 |
35 | CASK | 1.26749185 |
36 | MAPK15 | 1.23913464 |
37 | WNK3 | 1.23858488 |
38 | PNCK | 1.21727192 |
39 | CAMKK2 | 1.21319183 |
40 | CAMK2A | 1.19074120 |
41 | KSR1 | 1.16976221 |
42 | UHMK1 | 1.16382878 |
43 | MAPKAPK5 | 1.12714306 |
44 | MUSK | 1.11391053 |
45 | DYRK2 | 1.07674891 |
46 | CSNK1G1 | 1.06638299 |
47 | MAPK13 | 1.04363117 |
48 | TRIM28 | 1.03272224 |
49 | MAP3K13 | 1.01740002 |
50 | SIK2 | 1.00428033 |
51 | SGK2 | 1.00417388 |
52 | CSNK1G2 | 0.99579956 |
53 | PAK3 | 0.98959073 |
54 | SGK3 | 0.98908619 |
55 | RET | 0.98858522 |
56 | CAMK1G | 0.98580943 |
57 | FES | 0.97454235 |
58 | CAMK2B | 0.94975068 |
59 | PRKCG | 0.93351105 |
60 | CDC42BPA | 0.92607084 |
61 | STK38 | 0.92126127 |
62 | TRIB3 | 0.91965295 |
63 | OXSR1 | 0.91012843 |
64 | SGK223 | 0.89791443 |
65 | SGK494 | 0.89791443 |
66 | DAPK1 | 0.88902046 |
67 | CDK19 | 0.88097886 |
68 | NEK9 | 0.87622254 |
69 | MAP3K1 | 0.86677853 |
70 | GRK7 | 0.86223056 |
71 | PDGFRA | 0.86032312 |
72 | FGR | 0.84313945 |
73 | ADRBK2 | 0.83688397 |
74 | CAMK2D | 0.83504816 |
75 | CCNB1 | 0.82027297 |
76 | ARAF | 0.80542054 |
77 | ROCK2 | 0.78791962 |
78 | MOS | 0.76458448 |
79 | FRK | 0.76250329 |
80 | TYRO3 | 0.75919731 |
81 | HIPK2 | 0.74137563 |
82 | SGK1 | 0.73651153 |
83 | WNK4 | 0.73145662 |
84 | MAPK12 | 0.72193653 |
85 | ADRBK1 | 0.70460346 |
86 | MAP2K1 | 0.68957038 |
87 | CSNK1A1 | 0.68865100 |
88 | CDK15 | 0.68548973 |
89 | TNK2 | 0.68430906 |
90 | CDK18 | 0.68142555 |
91 | PLK2 | 0.67362569 |
92 | DYRK1A | 0.67158526 |
93 | CSNK1A1L | 0.67075438 |
94 | STK11 | 0.66983307 |
95 | FGFR2 | 0.65721255 |
96 | CDK14 | 0.65186078 |
97 | CAMK2G | 0.64652950 |
98 | DMPK | 0.63759984 |
99 | PTK2 | 0.63462325 |
100 | CAMK4 | 0.63095247 |
101 | RPS6KA5 | 0.62325500 |
102 | WNK1 | 0.62191726 |
103 | STK39 | 0.62073150 |
104 | SIK1 | 0.62039754 |
105 | PRKG1 | 0.61263259 |
106 | PRKCE | 0.60130171 |
107 | RPS6KA3 | 0.59297113 |
108 | EPHB1 | 0.57762538 |
109 | PRPF4B | 0.57668183 |
110 | MARK2 | 0.56934036 |
111 | CDK11A | 0.56675045 |
112 | PIK3CG | 0.56544495 |
113 | CSNK1G3 | 0.53624144 |
114 | MAPK10 | 0.53050680 |
115 | PRKDC | 0.52413260 |
116 | PDPK1 | 0.51637764 |
117 | GRK1 | 0.51376696 |
118 | CAMK1 | 0.50999447 |
119 | PTK2B | 0.49544522 |
120 | LATS2 | 0.49535772 |
121 | ROCK1 | 0.49317212 |
122 | FYN | 0.48806835 |
123 | FER | 0.48691596 |
124 | BCKDK | 0.48562997 |
125 | TLK1 | 0.48284933 |
126 | PIK3CA | 0.46095144 |
127 | PDK1 | 0.46052635 |
128 | PRKCQ | 0.45574951 |
129 | RIPK1 | 0.44772216 |
130 | RPS6KA2 | 0.44513113 |
131 | PRKD2 | 0.44075517 |
132 | TAOK1 | 0.44048126 |
133 | TIE1 | 0.43662783 |
134 | SCYL2 | 0.42277498 |
135 | CSNK1D | 0.40771493 |
136 | PRKACA | 0.39944455 |
137 | PRKCZ | 0.39231427 |
138 | MAP4K2 | 0.38619429 |
139 | MAP3K7 | 0.38391549 |
140 | PRKACB | 0.32709428 |
141 | MAPK7 | 0.30394971 |
142 | PRKAA1 | 0.28091151 |
143 | CAMK1D | 0.27186402 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 2.82572309 |
2 | Cocaine addiction_Homo sapiens_hsa05030 | 2.68734041 |
3 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.65932963 |
4 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.49561784 |
5 | * Insulin secretion_Homo sapiens_hsa04911 | 2.44214345 |
6 | GABAergic synapse_Homo sapiens_hsa04727 | 2.43468083 |
7 | Circadian entrainment_Homo sapiens_hsa04713 | 2.36857094 |
8 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.33159496 |
9 | Olfactory transduction_Homo sapiens_hsa04740 | 2.24839828 |
10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.21608127 |
11 | Morphine addiction_Homo sapiens_hsa05032 | 2.14388018 |
12 | Long-term potentiation_Homo sapiens_hsa04720 | 2.13101491 |
13 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.10238212 |
14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.09545414 |
15 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.08743729 |
16 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.06252449 |
17 | Salivary secretion_Homo sapiens_hsa04970 | 1.91278819 |
18 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.84119107 |
19 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.82070965 |
20 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.73135736 |
21 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.71212588 |
22 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.67851359 |
23 | Renin secretion_Homo sapiens_hsa04924 | 1.67449443 |
24 | Taste transduction_Homo sapiens_hsa04742 | 1.62911637 |
25 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.61869896 |
26 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.61274022 |
27 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.56897983 |
28 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.53129277 |
29 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.47257313 |
30 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.43083029 |
31 | Long-term depression_Homo sapiens_hsa04730 | 1.41227291 |
32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.40640105 |
33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.39041399 |
34 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.30816453 |
35 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.28445175 |
36 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.28246261 |
37 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.28117838 |
38 | Gap junction_Homo sapiens_hsa04540 | 1.27573285 |
39 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.27505673 |
40 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.24056738 |
41 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.23014375 |
42 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.22339256 |
43 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.17261088 |
44 | Phototransduction_Homo sapiens_hsa04744 | 1.16635377 |
45 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.16075017 |
46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.12042916 |
47 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.09607938 |
48 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.08252357 |
49 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.08223449 |
50 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.06727882 |
51 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.06093892 |
52 | Melanogenesis_Homo sapiens_hsa04916 | 1.04259245 |
53 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.01831440 |
54 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.01695750 |
55 | ABC transporters_Homo sapiens_hsa02010 | 1.01045050 |
56 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.00687963 |
57 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.00549461 |
58 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.00355136 |
59 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.99288500 |
60 | Circadian rhythm_Homo sapiens_hsa04710 | 0.99068367 |
61 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.98606227 |
62 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.95630946 |
63 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.91310408 |
64 | Glioma_Homo sapiens_hsa05214 | 0.89002274 |
65 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.88725582 |
66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.88572864 |
67 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.88286357 |
68 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.86207914 |
69 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.82631530 |
70 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.80180997 |
71 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.80065438 |
72 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.79437534 |
73 | Axon guidance_Homo sapiens_hsa04360 | 0.77981729 |
74 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.77952432 |
75 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.75102814 |
76 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.73818454 |
77 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.70332223 |
78 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.69586705 |
79 | Histidine metabolism_Homo sapiens_hsa00340 | 0.69093392 |
80 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.68323622 |
81 | Prion diseases_Homo sapiens_hsa05020 | 0.66902796 |
82 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.66614296 |
83 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.66467346 |
84 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.64025940 |
85 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.63988172 |
86 | Alcoholism_Homo sapiens_hsa05034 | 0.63638835 |
87 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.63201495 |
88 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.62890936 |
89 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.61200949 |
90 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.60497053 |
91 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59866630 |
92 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.59621841 |
93 | Lysosome_Homo sapiens_hsa04142 | 0.59206800 |
94 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.57933960 |
95 | Bile secretion_Homo sapiens_hsa04976 | 0.55691831 |
96 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.51363421 |
97 | Peroxisome_Homo sapiens_hsa04146 | 0.51221331 |
98 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.51020342 |
99 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.49588690 |
100 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.49086568 |
101 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.48886704 |
102 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.48607497 |
103 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.48122893 |
104 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.47912675 |
105 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.47197333 |
106 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.45373490 |
107 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.45247729 |
108 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.43697920 |
109 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.43528188 |
110 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.42889494 |
111 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.42864846 |
112 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.42200428 |
113 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.40258936 |
114 | Endocytosis_Homo sapiens_hsa04144 | 0.39745821 |
115 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.39581075 |
116 | Endometrial cancer_Homo sapiens_hsa05213 | 0.38365340 |
117 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.36501562 |
118 | Insulin resistance_Homo sapiens_hsa04931 | 0.35886749 |
119 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.34973066 |
120 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.34578030 |
121 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.32994079 |
122 | Parkinsons disease_Homo sapiens_hsa05012 | 0.32939739 |
123 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.32699891 |
124 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.32391640 |
125 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.32313136 |
126 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.30694150 |
127 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.28662030 |
128 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.28434115 |
129 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.27563552 |
130 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.27541318 |
131 | Alzheimers disease_Homo sapiens_hsa05010 | 0.27375101 |