KCTD10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene binds proliferating cell nuclear antigen (PCNA) and may be involved in DNA synthesis and cell proliferation. In addition, the encoded protein may be a tumor suppressor. Several protein-coding and non-protein coding transcript variants have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of osteoblast proliferation (GO:0033690)4.55153020
2cell adhesion mediated by integrin (GO:0033627)4.50045604
3vascular endothelial growth factor signaling pathway (GO:0038084)4.14132800
4chondrocyte proliferation (GO:0035988)4.12507304
5endodermal cell differentiation (GO:0035987)4.10099610
6type B pancreatic cell proliferation (GO:0044342)4.08869989
7regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.86379819
8collagen fibril organization (GO:0030199)3.85235630
9negative regulation of fatty acid transport (GO:2000192)3.84727464
10wound healing, spreading of epidermal cells (GO:0035313)3.81286426
11endothelial tube morphogenesis (GO:0061154)3.77791867
12morphogenesis of an endothelium (GO:0003159)3.77791867
13negative regulation of axon extension involved in axon guidance (GO:0048843)3.77727752
14ganglion development (GO:0061548)3.75892936
15skin morphogenesis (GO:0043589)3.66909971
16regulation of tight junction assembly (GO:2000810)3.66655693
17axon extension involved in axon guidance (GO:0048846)3.64476896
18neuron projection extension involved in neuron projection guidance (GO:1902284)3.64476896
19basement membrane organization (GO:0071711)3.60372847
20positive regulation of endothelial cell apoptotic process (GO:2000353)3.55808728
21regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.53003613
22protein heterotrimerization (GO:0070208)3.51794040
23epithelial cell-cell adhesion (GO:0090136)3.50040792
24mitotic nuclear envelope reassembly (GO:0007084)3.42414116
25nuclear envelope reassembly (GO:0031468)3.42414116
26hippo signaling (GO:0035329)3.41149085
27cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.37053193
28stress fiber assembly (GO:0043149)3.36711635
29cell migration involved in sprouting angiogenesis (GO:0002042)3.30341245
30wound healing, spreading of cells (GO:0044319)3.29470139
31apoptotic cell clearance (GO:0043277)3.26458861
32extracellular matrix assembly (GO:0085029)3.25455131
33adhesion of symbiont to host cell (GO:0044650)3.23723367
34virion attachment to host cell (GO:0019062)3.23723367
35activation of MAPKKK activity (GO:0000185)3.23703056
36regulation of axon extension involved in axon guidance (GO:0048841)3.23323401
37sequestering of extracellular ligand from receptor (GO:0035581)3.22786246
38mesodermal cell differentiation (GO:0048333)3.16263806
39extracellular fibril organization (GO:0043206)3.15099560
40kidney mesenchyme development (GO:0072074)3.13884102
41Golgi transport vesicle coating (GO:0048200)3.12991110
42COPI coating of Golgi vesicle (GO:0048205)3.12991110
43plasma membrane repair (GO:0001778)3.12230135
44positive regulation of epithelial to mesenchymal transition (GO:0010718)3.11969593
45heparan sulfate proteoglycan biosynthetic process (GO:0015012)3.08643789
46substrate adhesion-dependent cell spreading (GO:0034446)3.06770634
47negative regulation of axon guidance (GO:1902668)3.05341923
48semaphorin-plexin signaling pathway (GO:0071526)3.03823781
49cell-substrate junction assembly (GO:0007044)3.03641855
50positive regulation of blood vessel endothelial cell migration (GO:0043536)3.03357760
51atrioventricular valve morphogenesis (GO:0003181)3.01893308
52renal filtration (GO:0097205)2.99855582
53substrate-dependent cell migration (GO:0006929)2.99224087
54axon extension (GO:0048675)2.98633857
55blood vessel endothelial cell migration (GO:0043534)2.97667851
56planar cell polarity pathway involved in neural tube closure (GO:0090179)2.96856736
57hypotonic response (GO:0006971)2.92796876
58cellular response to interferon-alpha (GO:0035457)2.91895522
59regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.91043951
60adherens junction assembly (GO:0034333)2.90095010
61fibril organization (GO:0097435)2.86970134
62lymphangiogenesis (GO:0001946)2.86430153
63L-serine transport (GO:0015825)2.86251717
64blood vessel maturation (GO:0001955)2.84683559
65regulation of SMAD protein import into nucleus (GO:0060390)2.84343154
66retina vasculature morphogenesis in camera-type eye (GO:0061299)2.83574512
67hemidesmosome assembly (GO:0031581)2.83319145
68endocardial cushion development (GO:0003197)2.83152069
69regulation of axon guidance (GO:1902667)2.82886023
70protein retention in ER lumen (GO:0006621)2.82789787
71adenine nucleotide transport (GO:0051503)2.81930377
72regulation of osteoblast proliferation (GO:0033688)2.81533499
73metanephric mesenchyme development (GO:0072075)2.80161058
74muscle cell migration (GO:0014812)2.78379886
75negative regulation of anoikis (GO:2000811)2.77541448
76regulation of hippo signaling (GO:0035330)2.76684367
77positive regulation of endothelial cell migration (GO:0010595)2.76079127
78peptidyl-proline hydroxylation (GO:0019511)2.74655287
79protein localization to endosome (GO:0036010)2.74620179
80adhesion of symbiont to host (GO:0044406)2.73246395
81neuron projection extension (GO:1990138)2.72713685
82facial nerve structural organization (GO:0021612)2.71953802
83negative regulation of stem cell proliferation (GO:2000647)2.68628544
84cellular response to vitamin D (GO:0071305)2.68429637
85endothelial cell morphogenesis (GO:0001886)2.68358730
86actin filament depolymerization (GO:0030042)2.66313891
87protein localization to cell surface (GO:0034394)2.65214761
88protein hydroxylation (GO:0018126)2.64822137
89positive regulation of axon extension (GO:0045773)2.62236029
90collagen metabolic process (GO:0032963)2.61902567
91negative regulation of JAK-STAT cascade (GO:0046426)2.61405205
92purine ribonucleotide transport (GO:0015868)2.59546546
93positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511)2.58623560
94serine transport (GO:0032329)2.58590504
95response to laminar fluid shear stress (GO:0034616)2.57964624
96polarized epithelial cell differentiation (GO:0030859)2.57197003
97extracellular matrix disassembly (GO:0022617)2.56400045
98dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.56312543
99regulation of integrin-mediated signaling pathway (GO:2001044)2.56027751
100barbed-end actin filament capping (GO:0051016)2.53184199
101bone trabecula formation (GO:0060346)2.52834011
102collagen catabolic process (GO:0030574)2.50364701
103multicellular organismal macromolecule metabolic process (GO:0044259)2.49840711
104glomerular filtration (GO:0003094)2.49401321
105platelet aggregation (GO:0070527)2.49087711
106cellular response to vitamin (GO:0071295)2.48964110
107mesenchymal-epithelial cell signaling (GO:0060638)2.47841496
108negative regulation of smooth muscle cell migration (GO:0014912)2.47394273
109fibroblast migration (GO:0010761)2.45546247
110regulation of early endosome to late endosome transport (GO:2000641)2.45375981
111protein targeting to plasma membrane (GO:0072661)2.42860887
112response to fluid shear stress (GO:0034405)2.41914923
113cell migration involved in heart development (GO:0060973)2.41027576
114positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.40717885
115negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)2.40466962
116positive regulation of SMAD protein import into nucleus (GO:0060391)2.40166017
117germ cell migration (GO:0008354)2.40011517
118regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.39354846
119maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.37186446
120glomerular basement membrane development (GO:0032836)2.37101913
121vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.37088469
122negative regulation of adherens junction organization (GO:1903392)2.36278499
123negative regulation of focal adhesion assembly (GO:0051895)2.36278499
124negative regulation of cell junction assembly (GO:1901889)2.36278499
125negative regulation of chondrocyte differentiation (GO:0032331)2.34379332
126multicellular organismal catabolic process (GO:0044243)2.34050075
127multicellular organismal metabolic process (GO:0044236)2.33156700
128branching involved in salivary gland morphogenesis (GO:0060445)2.33013025
129lymph vessel development (GO:0001945)2.32123695
130establishment of endothelial barrier (GO:0061028)2.32039173
131negative regulation of cell size (GO:0045792)2.31361162
132glomerular visceral epithelial cell development (GO:0072015)2.31026262
133positive regulation of lamellipodium assembly (GO:0010592)2.30843387
134surfactant homeostasis (GO:0043129)2.30796186
135mRNA transcription (GO:0009299)2.28042430
136patterning of blood vessels (GO:0001569)2.28042429
137craniofacial suture morphogenesis (GO:0097094)2.27612367
138cytoskeletal anchoring at plasma membrane (GO:0007016)2.27453201
139endothelial cell chemotaxis (GO:0035767)2.27396551
140negative regulation of catenin import into nucleus (GO:0035414)2.26824669
141endothelial cell migration (GO:0043542)2.24931687

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human4.42777904
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.21202944
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse4.11694951
4TRIM28_21343339_ChIP-Seq_HEK293_Human3.94275072
5RARG_19884340_ChIP-ChIP_MEFs_Mouse3.84764402
6CLOCK_20551151_ChIP-Seq_293T_Human3.00569650
7ELK3_25401928_ChIP-Seq_HUVEC_Human2.66514054
8FOXM1_23109430_ChIP-Seq_U2OS_Human2.50198969
9* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.49501318
10TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.40274940
11SMAD_19615063_ChIP-ChIP_OVARY_Human2.31139822
12TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.28373057
13HIF1A_21447827_ChIP-Seq_MCF-7_Human2.17373897
14MYC_22102868_ChIP-Seq_BL_Human2.06410038
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.02900245
16KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.97479308
17* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.84843933
18ATF3_27146783_Chip-Seq_COLON_Human1.83584396
19KDM2B_26808549_Chip-Seq_SUP-B15_Human1.83285891
20E2F7_22180533_ChIP-Seq_HELA_Human1.82241669
21* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.80173912
22SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.76356651
23SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.76356651
24STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.74868891
25SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.73210586
26TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.73053899
27NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.69198416
28KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.68691374
29P300_27058665_Chip-Seq_ZR-75-30cells_Human1.67181875
30BRD4_25478319_ChIP-Seq_HGPS_Human1.65160216
31KDM2B_26808549_Chip-Seq_DND41_Human1.64297309
32VDR_21846776_ChIP-Seq_THP-1_Human1.61488538
33RACK7_27058665_Chip-Seq_MCF-7_Human1.61256836
34RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.58299507
35STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.58019044
36PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.56440438
37AR_21909140_ChIP-Seq_LNCAP_Human1.54456236
38* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.54140321
39ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.53870067
40MYB_21317192_ChIP-Seq_ERMYB_Mouse1.52268691
41STAT6_21828071_ChIP-Seq_BEAS2B_Human1.51832699
42* TCF7_22412390_ChIP-Seq_EML_Mouse1.51527361
43ESR2_21235772_ChIP-Seq_MCF-7_Human1.51382827
44PPAR_26484153_Chip-Seq_NCI-H1993_Human1.50915919
45EED_16625203_ChIP-ChIP_MESCs_Mouse1.49693519
46EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.47611342
47UBF1/2_26484160_Chip-Seq_HMECs_Human1.47367234
48NFIB_24661679_ChIP-Seq_LUNG_Mouse1.47027340
49CJUN_26792858_Chip-Seq_BT549_Human1.46411575
50KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.45491029
51WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.43736148
52HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.42741774
53SOX9_24532713_ChIP-Seq_HFSC_Mouse1.41817785
54ESR1_21235772_ChIP-Seq_MCF-7_Human1.39713784
55GATA2_21666600_ChIP-Seq_HMVEC_Human1.39463335
56TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.39030464
57ZNF263_19887448_ChIP-Seq_K562_Human1.37426082
58MAF_26560356_Chip-Seq_TH1_Human1.36387486
59JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.36157099
60TP53_22127205_ChIP-Seq_IMR90_Human1.36088390
61FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.35879731
62UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.32658575
63* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.32615347
64PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.32513095
65FOXO3_23340844_ChIP-Seq_DLD1_Human1.31360466
66ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.31015184
67NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.30077359
68SMC3_22415368_ChIP-Seq_MEFs_Mouse1.29383839
69KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.28796084
70SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.28153267
71ZNF217_24962896_ChIP-Seq_MCF-7_Human1.26990471
72* LXR_22292898_ChIP-Seq_THP-1_Human1.25432562
73UTX_26944678_Chip-Seq_JUKART_Human1.25240688
74THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.24325191
75SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.23282205
76KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.23016719
77NCOR1_26117541_ChIP-Seq_K562_Human1.22333673
78PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.21584044
79TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20840594
80BRD4_27068464_Chip-Seq_AML-cells_Mouse1.20833042
81ZFP281_18757296_ChIP-ChIP_E14_Mouse1.20586831
82* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.19987390
83TP53_18474530_ChIP-ChIP_U2OS_Human1.19972065
84ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.19799738
85CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.19759660
86ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.19162070
87RBPJ_22232070_ChIP-Seq_NCS_Mouse1.19113477
88NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.18899600
89NRF2_20460467_ChIP-Seq_MEFs_Mouse1.18899600
90TBX20_22080862_ChIP-Seq_HEART_Mouse1.18758202
91TBX20_22328084_ChIP-Seq_HEART_Mouse1.18758202
92NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.17583795
93ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.17538488
94ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.17316851
95SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.17058471
96SALL4_18804426_ChIP-ChIP_XEN_Mouse1.16773718
97EZH2_18974828_ChIP-Seq_MESCs_Mouse1.16090717
98RNF2_18974828_ChIP-Seq_MESCs_Mouse1.16090717
99SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.15732931
100POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.14974730
101* TP53_23651856_ChIP-Seq_MEFs_Mouse1.13443180
102SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.13139206
103SA1_22415368_ChIP-Seq_MEFs_Mouse1.12812095
104TP53_16413492_ChIP-PET_HCT116_Human1.11931417
105HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.11022233
106KDM2B_26808549_Chip-Seq_JURKAT_Human1.10147456
107TP53_20018659_ChIP-ChIP_R1E_Mouse1.09477375
108SMC1_22415368_ChIP-Seq_MEFs_Mouse1.09216011
109ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.08183808
110VDR_24763502_ChIP-Seq_THP-1_Human1.07619069
111WT1_19549856_ChIP-ChIP_CCG9911_Human1.07302510
112JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.06873382
113TET1_21490601_ChIP-Seq_MESCs_Mouse1.06807783
114P63_26484246_Chip-Seq_KERATINOCYTES_Human1.06608745
115DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.06483974
116* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.04888272
117* ISL1_27105846_Chip-Seq_CPCs_Mouse1.04668268
118* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.02754395
119EP300_21415370_ChIP-Seq_HL-1_Mouse1.01392011
120KDM2B_26808549_Chip-Seq_K562_Human0.99811205
121RUNX1_27514584_Chip-Seq_MCF-7_Human0.99409139
122NFI_21473784_ChIP-Seq_ESCs_Mouse0.99303376
123KLF4_18555785_ChIP-Seq_MESCs_Mouse0.99138857
124SOX2_20726797_ChIP-Seq_SW620_Human0.99073023
125ZFP281_27345836_Chip-Seq_ESCs_Mouse0.98680286
126* TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.98589792
127NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.98272133
128STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98192252
129OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.96220802
130EOMES_21245162_ChIP-Seq_HESCs_Human0.95967250
131MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.95650331
132MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.94714795
133ELK4_26923725_Chip-Seq_MESODERM_Mouse0.89459272
134EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.88580516

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen5.02092354
2MP0003705_abnormal_hypodermis_morpholog4.03312354
3MP0005275_abnormal_skin_tensile3.30085529
4MP0010352_gastrointestinal_tract_polyps3.02908841
5MP0003279_aneurysm3.02232977
6MP0001958_emphysema2.94528163
7MP0004272_abnormal_basement_membrane2.89579162
8MP0003566_abnormal_cell_adhesion2.79481942
9MP0006054_spinal_hemorrhage2.69451153
10MP0005503_abnormal_tendon_morphology2.56953986
11MP0010368_abnormal_lymphatic_system2.56748421
12MP0005623_abnormal_meninges_morphology2.51099211
13MP0005023_abnormal_wound_healing2.21949389
14MP0003091_abnormal_cell_migration2.13047498
15MP0003950_abnormal_plasma_membrane2.05918714
16MP0001879_abnormal_lymphatic_vessel1.76446179
17MP0003300_gastrointestinal_ulcer1.72572874
18MP0009384_cardiac_valve_regurgitation1.72051100
19MP0000733_abnormal_muscle_development1.64332429
20MP0010030_abnormal_orbit_morphology1.62016895
21MP0005076_abnormal_cell_differentiation1.61463277
22MP0000767_abnormal_smooth_muscle1.60638727
23MP0003941_abnormal_skin_development1.58299701
24MP0009278_abnormal_bone_marrow1.44951130
25MP0002877_abnormal_melanocyte_morpholog1.44201455
26MP0000762_abnormal_tongue_morphology1.43728697
27MP0000537_abnormal_urethra_morphology1.40775656
28MP0005508_abnormal_skeleton_morphology1.40165226
29MP0004808_abnormal_hematopoietic_stem1.38603192
30MP0002060_abnormal_skin_morphology1.29693490
31MP0009053_abnormal_anal_canal1.28605305
32MP0002295_abnormal_pulmonary_circulatio1.26589846
33MP0004084_abnormal_cardiac_muscle1.26430441
34MP0000751_myopathy1.24072916
35MP0003755_abnormal_palate_morphology1.19782283
36MP0000013_abnormal_adipose_tissue1.18147130
37MP0003385_abnormal_body_wall1.17945282
38MP0010307_abnormal_tumor_latency1.16321085
39MP0005595_abnormal_vascular_smooth1.16199902
40MP0003303_peritoneal_inflammation1.15109045
41MP0005257_abnormal_intraocular_pressure1.14202424
42MP0010234_abnormal_vibrissa_follicle1.11557901
43MP0000858_altered_metastatic_potential1.11440254
44MP0000534_abnormal_ureter_morphology1.11014845
45MP0002925_abnormal_cardiovascular_devel1.10885255
46MP0003045_fibrosis1.10849180
47MP0001243_abnormal_dermal_layer1.10388252
48MP0004782_abnormal_surfactant_physiolog1.08185187
49MP0005397_hematopoietic_system_phenotyp1.08005215
50MP0001545_abnormal_hematopoietic_system1.08005215
51MP0001849_ear_inflammation1.07362888
52MP0003115_abnormal_respiratory_system1.06233681
53MP0005501_abnormal_skin_physiology1.06024084
54MP0000750_abnormal_muscle_regeneration1.05921677
55MP0002128_abnormal_blood_circulation1.05723132
56MP0000343_altered_response_to1.04653158
57MP0001614_abnormal_blood_vessel1.04617322
58MP0003448_altered_tumor_morphology1.03664024
59MP0002282_abnormal_trachea_morphology1.02998151
60MP0001533_abnormal_skeleton_physiology1.02770140
61MP0000049_abnormal_middle_ear1.02491450
62MP0005197_abnormal_uvea_morphology1.02021989
63MP0002896_abnormal_bone_mineralization1.01581609
64MP0005390_skeleton_phenotype1.00638118
65MP0001915_intracranial_hemorrhage0.99879116
66MP0000428_abnormal_craniofacial_morphol0.98932446
67MP0009840_abnormal_foam_cell0.98789938
68MP0002933_joint_inflammation0.97956981
69MP0002796_impaired_skin_barrier0.97241214
70MP0001730_embryonic_growth_arrest0.92526520
71MP0005388_respiratory_system_phenotype0.91643598
72MP0002133_abnormal_respiratory_system0.91643598
73MP0003942_abnormal_urinary_system0.91570185
74MP0008004_abnormal_stomach_pH0.91216137
75MP0001299_abnormal_eye_distance/0.91087784
76MP0001348_abnormal_lacrimal_gland0.90631780
77MP0002086_abnormal_extraembryonic_tissu0.90463556
78MP0003828_pulmonary_edema0.88814363
79MP0005193_abnormal_anterior_eye0.88057235
80MP0002089_abnormal_postnatal_growth/wei0.87720719
81MP0010630_abnormal_cardiac_muscle0.86787802
82MP0002168_other_aberrant_phenotype0.86335425
83MP0000462_abnormal_digestive_system0.86045415
84MP0001175_abnormal_lung_morphology0.85977408
85MP0003984_embryonic_growth_retardation0.85835188
86MP0002177_abnormal_outer_ear0.85604073
87MP0004947_skin_inflammation0.85219932
88MP0009250_abnormal_appendicular_skeleto0.84779454
89MP0004858_abnormal_nervous_system0.84619258
90MP0002088_abnormal_embryonic_growth/wei0.84594086
91MP0001542_abnormal_bone_strength0.83564049
92MP0002113_abnormal_skeleton_development0.82895822
93MP0002396_abnormal_hematopoietic_system0.82809528
94MP0002108_abnormal_muscle_morphology0.82785910
95MP0000249_abnormal_blood_vessel0.81501859
96MP0006138_congestive_heart_failure0.81373691
97MP0005165_increased_susceptibility_to0.81202252
98MP0004197_abnormal_fetal_growth/weight/0.80553181
99MP0005164_abnormal_response_to0.78451160
100MP0003453_abnormal_keratinocyte_physiol0.78282101
101MP0008007_abnormal_cellular_replicative0.77965932
102MP0000003_abnormal_adipose_tissue0.77539888
103MP0001661_extended_life_span0.77446504
104MP0005409_darkened_coat_color0.77349875
105MP0000759_abnormal_skeletal_muscle0.77024331
106MP0000350_abnormal_cell_proliferation0.76163591
107MP0002932_abnormal_joint_morphology0.75826684
108MP0005058_abnormal_lysosome_morphology0.75321067
109MP0000516_abnormal_urinary_system0.74988448
110MP0005367_renal/urinary_system_phenotyp0.74988448
111MP0004883_abnormal_blood_vessel0.74810706
112MP0002998_abnormal_bone_remodeling0.74738692
113MP0000266_abnormal_heart_morphology0.74323903
114MP0003935_abnormal_craniofacial_develop0.74321465
115MP0000465_gastrointestinal_hemorrhage0.73571904
116MP0004087_abnormal_muscle_fiber0.73127189
117MP0005167_abnormal_blood-brain_barrier0.73070477
118MP0005380_embryogenesis_phenotype0.72461475
119MP0001672_abnormal_embryogenesis/_devel0.72461475
120MP0005394_taste/olfaction_phenotype0.72304119
121MP0005499_abnormal_olfactory_system0.72304119
122MP0000432_abnormal_head_morphology0.70473358
123MP0002166_altered_tumor_susceptibility0.70378724
124MP0002115_abnormal_skeleton_extremities0.70369430
125MP0001216_abnormal_epidermal_layer0.70263470
126MP0001697_abnormal_embryo_size0.70226804
127MP0000163_abnormal_cartilage_morphology0.70045770
128MP0008775_abnormal_heart_ventricle0.68395949
129MP0005621_abnormal_cell_physiology0.67504582
130MP0000579_abnormal_nail_morphology0.66830669
131MP0008789_abnormal_olfactory_epithelium0.66813127
132MP0005375_adipose_tissue_phenotype0.66460512
133MP0010771_integument_phenotype0.63518904
134MP0003795_abnormal_bone_structure0.62965734
135MP0004510_myositis0.60915913
136MP0002116_abnormal_craniofacial_bone0.60728844
137MP0002114_abnormal_axial_skeleton0.59414649
138MP0002254_reproductive_system_inflammat0.59337936

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.28255653
2Premature rupture of membranes (HP:0001788)5.74838077
3Cerebral aneurysm (HP:0004944)4.39717417
4Shallow orbits (HP:0000586)4.28652088
5Aortic dissection (HP:0002647)4.17736512
6Aortic aneurysm (HP:0004942)4.15728568
7Ankle contracture (HP:0006466)4.07246517
8Atrophic scars (HP:0001075)3.55308822
9Cervical subluxation (HP:0003308)3.54794198
10Dilatation of the ascending aorta (HP:0005111)3.53136550
11Peritonitis (HP:0002586)3.51083743
12Broad metatarsal (HP:0001783)3.46818237
13Bladder diverticulum (HP:0000015)3.19534125
14Wrist flexion contracture (HP:0001239)2.98181326
15Soft skin (HP:0000977)2.93180793
16Mitral valve prolapse (HP:0001634)2.92227376
17Short middle phalanx of the 5th finger (HP:0004220)2.91696094
18Genu recurvatum (HP:0002816)2.86237042
19Fragile skin (HP:0001030)2.76155286
20Vertebral compression fractures (HP:0002953)2.76137148
21Increased connective tissue (HP:0009025)2.72110276
22Short 4th metacarpal (HP:0010044)2.71998345
23Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.71998345
24Aneurysm (HP:0002617)2.68043293
25Bowel diverticulosis (HP:0005222)2.67038406
26Osteolytic defects of the hand bones (HP:0009699)2.65931401
27Osteolytic defects of the phalanges of the hand (HP:0009771)2.65931401
28Hematochezia (HP:0002573)2.65675269
29Wormian bones (HP:0002645)2.65656421
30Entropion (HP:0000621)2.61008906
31Increased density of long bones (HP:0006392)2.59728670
32Vascular tortuosity (HP:0004948)2.58285054
33Ulnar bowing (HP:0003031)2.55133232
34Blue sclerae (HP:0000592)2.53728750
35Congenital glaucoma (HP:0001087)2.46656311
36Spinal rigidity (HP:0003306)2.45215129
37Slender build (HP:0001533)2.42186906
38Abnormality of dentin (HP:0010299)2.39838407
39Arterial tortuosity (HP:0005116)2.37557380
40Camptodactyly of toe (HP:0001836)2.37333263
41Interstitial pulmonary disease (HP:0006530)2.37177630
42Natal tooth (HP:0000695)2.36196588
43Biconcave vertebral bodies (HP:0004586)2.34191256
44Radial bowing (HP:0002986)2.31436421
45Deviation of the hallux (HP:0010051)2.26394520
46Hallux valgus (HP:0001822)2.22471657
47Short nail (HP:0001799)2.20981968
48Abnormality of the acetabulum (HP:0003170)2.20045632
49Distal lower limb amyotrophy (HP:0008944)2.18981983
50Distal upper limb amyotrophy (HP:0007149)2.17310517
51Upper limb amyotrophy (HP:0009129)2.17310517
52Bowed forearm bones (HP:0003956)2.16156830
53Bowing of the arm (HP:0006488)2.16156830
54Hypoventilation (HP:0002791)2.14135954
55Megalocornea (HP:0000485)2.12315668
56Difficulty climbing stairs (HP:0003551)2.12129062
57Polycythemia (HP:0001901)2.09607092
58Aortic valve stenosis (HP:0001650)2.07137289
59Neonatal short-limb short stature (HP:0008921)2.06335476
60Long palpebral fissure (HP:0000637)2.06331146
61Long toe (HP:0010511)2.05841213
62Abnormality of the peritoneum (HP:0002585)2.04983279
63Hyperacusis (HP:0010780)2.04128841
64Type 1 muscle fiber predominance (HP:0003803)2.03402250
65Nonimmune hydrops fetalis (HP:0001790)2.03231310
66Disproportionate tall stature (HP:0001519)2.02712903
67Abnormality of the 4th metacarpal (HP:0010012)2.02661505
68Spondylolisthesis (HP:0003302)2.02531099
69Hyperextensible skin (HP:0000974)2.02470239
70Broad ribs (HP:0000885)2.02407797
71Abnormality of the calcaneus (HP:0008364)2.00848212
72Thin bony cortex (HP:0002753)2.00684697
73Elbow flexion contracture (HP:0002987)1.97836067
74Hand muscle atrophy (HP:0009130)1.96699997
75Spinal cord lesions (HP:0100561)1.94815665
76Syringomyelia (HP:0003396)1.94815665
77Mitral regurgitation (HP:0001653)1.94318876
78Joint stiffness (HP:0001387)1.93686136
79Thick nail (HP:0001805)1.93674759
80Aortic regurgitation (HP:0001659)1.93032568
81Right ventricular cardiomyopathy (HP:0011663)1.92152224
82Broad face (HP:0000283)1.91767251
83Joint laxity (HP:0001388)1.90360032
84Complete atrioventricular canal defect (HP:0001674)1.90147146
85Mesomelia (HP:0003027)1.88525273
86Persistence of primary teeth (HP:0006335)1.87892326
87Flexion contracture of toe (HP:0005830)1.85240085
88Joint contractures involving the joints of the feet (HP:0100492)1.85240085
89Coxa vara (HP:0002812)1.83657339
90Renal duplication (HP:0000075)1.83194054
91Mildly elevated creatine phosphokinase (HP:0008180)1.82457967
92Striae distensae (HP:0001065)1.82283657
93Scapular winging (HP:0003691)1.81911199
94Bicuspid aortic valve (HP:0001647)1.81872883
95Delayed cranial suture closure (HP:0000270)1.80893318
96Abnormality of the nasal mucosa (HP:0000433)1.78163495
97Lower limb amyotrophy (HP:0007210)1.77763973
98Follicular hyperkeratosis (HP:0007502)1.77652988
99Rectal prolapse (HP:0002035)1.76942435
100Tibial bowing (HP:0002982)1.76753661
101Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.74152924
102Buphthalmos (HP:0000557)1.73801876
103Ectopia lentis (HP:0001083)1.73415484
104Reduced subcutaneous adipose tissue (HP:0003758)1.73347166
105Abnormality of the distal phalanx of the thumb (HP:0009617)1.72918068
106Selective tooth agenesis (HP:0001592)1.72605136
107Bradycardia (HP:0001662)1.71801792
108Supranuclear gaze palsy (HP:0000605)1.71782785
109Lymphangioma (HP:0100764)1.71559217
110Osteopenia (HP:0000938)1.71170836
111Abnormality of skull ossification (HP:0002703)1.69280985
112Platyspondyly (HP:0000926)1.68229613
113Coronal craniosynostosis (HP:0004440)1.67423975
114Abnormality of the distal phalanges of the toes (HP:0010182)1.66963513
115Subacute progressive viral hepatitis (HP:0006572)1.66405904
116Thoracolumbar scoliosis (HP:0002944)1.66287360
117Short clavicles (HP:0000894)1.66228367
118Knee flexion contracture (HP:0006380)1.65675518
119Increased variability in muscle fiber diameter (HP:0003557)1.65573449
120Broad long bones (HP:0005622)1.65126743
121Flat acetabular roof (HP:0003180)1.64862599
122Insomnia (HP:0100785)1.64138583
123Abnormal delivery (HP:0001787)1.64118201
124Broad palm (HP:0001169)1.64101844
125Venous abnormality (HP:0002624)1.63866687
126Wide anterior fontanel (HP:0000260)1.63747208
127Overgrowth (HP:0001548)1.62359257
128Hydroureter (HP:0000072)1.61505421
129Mesangial abnormality (HP:0001966)1.61056351
130Delayed closure of the anterior fontanelle (HP:0001476)1.60948607
131Enlarged penis (HP:0000040)1.60372908
132Flat cornea (HP:0007720)1.60298298
133Short 5th finger (HP:0009237)1.59913347
134Asymmetry of the thorax (HP:0001555)1.59787772
135Vertebral arch anomaly (HP:0008438)1.57933975

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.27346109
2TTN3.46589673
3PKN22.86577072
4PDGFRA2.55414602
5LATS12.49337960
6ERN12.44417862
7DDR22.37571838
8EEF2K2.30046113
9AKT32.23384881
10LRRK22.20784417
11RIPK12.18217662
12TESK12.14425454
13LATS22.14152887
14KDR2.13504155
15ARAF2.02977872
16TGFBR21.93229450
17TIE11.91428931
18PAK41.87599407
19STK101.82607707
20RPS6KA41.73594998
21EPHB21.72320157
22PTK61.59893968
23PAK21.53811821
24PTK21.53531301
25PRKD21.53443359
26EPHA21.53097973
27ERBB41.50896784
28TGFBR11.48426899
29MAP3K131.47776454
30ICK1.45752934
31MAP3K101.42823258
32MAP3K91.40312464
33RPS6KA21.39725068
34DMPK1.38490797
35PIM21.33225360
36LIMK11.32350488
37GRK71.31080579
38MAP3K31.30324528
39SCYL21.22516938
40FER1.22479655
41SIK11.21546698
42STK31.21344664
43STK381.20744467
44BCR1.19773100
45EPHA31.19468581
46ILK1.16047373
47MAP2K31.15150682
48BMX1.14584950
49CDC42BPA1.14400324
50PDGFRB1.12921641
51PDK21.09497815
52MAP3K61.08981531
53MAPKAPK31.06435336
54TESK21.04774106
55FGFR41.04603386
56MAP3K81.01024541
57EPHB11.00117211
58TAOK10.99880017
59BRAF0.98315397
60MYLK0.98181116
61ZAP700.98118327
62NEK20.97454916
63MTOR0.97421273
64JAK30.96920154
65IRAK30.96329876
66FGFR10.95494849
67NEK90.95442541
68TRPM70.95149016
69TRIM280.93282420
70SIK30.92225751
71CDK60.89586915
72PTK2B0.89332559
73TAOK20.87842680
74PAK30.83416952
75NEK10.82869671
76ABL20.76962835
77MAP3K110.76840264
78CDK120.76590598
79FLT30.74405315
80PRKG20.73270229
81RET0.73004939
82FGFR30.71856896
83KSR10.71547928
84CLK10.71446730
85MAP4K10.68184045
86JAK10.66017532
87MAP2K10.65953690
88KSR20.65581987
89ROCK10.64917868
90PRKD30.64862448
91RPS6KB20.64610379
92MOS0.64083853
93PRPF4B0.63394453
94MARK10.59629809
95GSK3A0.59494131
96MET0.58934850
97TBK10.58778330
98PAK10.57897148
99LMTK20.55757717
100ADRBK10.54365419
101KIT0.54247834
102BRD40.53792172
103MARK20.49064334
104MAP3K140.48852858
105BUB10.48173846
106ALK0.47341866
107TYK20.47307873
108DYRK30.45622161
109MAPKAPK20.43373584
110RPS6KL10.42665569
111RPS6KC10.42665569
112STK38L0.42624272
113PRKD10.42301714
114SMG10.41252090
115CDK80.40993456
116DYRK1B0.40654817
117NTRK10.39386182
118CSNK1A1L0.38223718
119CDK140.37752983
120CHUK0.37272447
121EGFR0.36675888
122CAMK1D0.36315083
123DAPK30.36298456
124AURKB0.36046808
125HCK0.35693579
126CDK180.35297226
127INSR0.34435536
128FGFR20.34318886
129PRKCH0.33811690
130CSK0.33618303
131MARK30.32630678
132ROCK20.32035690
133SRC0.31262907
134PIM10.31195420
135CDK150.30707941
136MAPK70.30697559
137CDK40.29385178
138ITK0.29142598
139BRSK20.28128739
140MAP3K120.26596268
141CDK11A0.26337645

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.70376328
2Focal adhesion_Homo sapiens_hsa045102.43065489
3Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.41335818
4Adherens junction_Homo sapiens_hsa045202.17074234
5Small cell lung cancer_Homo sapiens_hsa052222.10426201
6Proteoglycans in cancer_Homo sapiens_hsa052052.02143004
7AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.99558689
8Chronic myeloid leukemia_Homo sapiens_hsa052201.91466814
9Bladder cancer_Homo sapiens_hsa052191.89926239
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.83857208
11Leukocyte transendothelial migration_Homo sapiens_hsa046701.79098874
12Shigellosis_Homo sapiens_hsa051311.75303615
13Amoebiasis_Homo sapiens_hsa051461.68249787
14Viral myocarditis_Homo sapiens_hsa054161.67389033
15Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.65754449
16Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.65393555
17Hippo signaling pathway_Homo sapiens_hsa043901.60119633
18MicroRNAs in cancer_Homo sapiens_hsa052061.59788741
19p53 signaling pathway_Homo sapiens_hsa041151.54295153
20Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.48993656
21Toxoplasmosis_Homo sapiens_hsa051451.48121821
22TGF-beta signaling pathway_Homo sapiens_hsa043501.47325615
23Pancreatic cancer_Homo sapiens_hsa052121.46419389
24Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.42005247
25Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.36373941
26Regulation of actin cytoskeleton_Homo sapiens_hsa048101.36203122
27Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.34810827
28Axon guidance_Homo sapiens_hsa043601.33665989
29Vibrio cholerae infection_Homo sapiens_hsa051101.32371674
30Dilated cardiomyopathy_Homo sapiens_hsa054141.30199660
31Malaria_Homo sapiens_hsa051441.30170654
32Platelet activation_Homo sapiens_hsa046111.26318534
33VEGF signaling pathway_Homo sapiens_hsa043701.25322511
34HTLV-I infection_Homo sapiens_hsa051661.22977230
35Leishmaniasis_Homo sapiens_hsa051401.22176004
36Colorectal cancer_Homo sapiens_hsa052101.19737923
37Thyroid cancer_Homo sapiens_hsa052161.18286120
38PI3K-Akt signaling pathway_Homo sapiens_hsa041511.16951292
39Apoptosis_Homo sapiens_hsa042101.16762801
40Salmonella infection_Homo sapiens_hsa051321.13970637
41TNF signaling pathway_Homo sapiens_hsa046681.11826724
42Cell cycle_Homo sapiens_hsa041101.08929330
43Neurotrophin signaling pathway_Homo sapiens_hsa047221.08871945
44Viral carcinogenesis_Homo sapiens_hsa052031.08641367
45Pathways in cancer_Homo sapiens_hsa052001.08573261
46Other glycan degradation_Homo sapiens_hsa005111.08463695
47Rap1 signaling pathway_Homo sapiens_hsa040151.07628821
48Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.06670871
49Hepatitis B_Homo sapiens_hsa051611.04670118
50Renal cell carcinoma_Homo sapiens_hsa052111.04099147
51HIF-1 signaling pathway_Homo sapiens_hsa040661.03769718
52Tight junction_Homo sapiens_hsa045301.03448950
53Endometrial cancer_Homo sapiens_hsa052131.02663414
54Protein digestion and absorption_Homo sapiens_hsa049741.00395218
55Glioma_Homo sapiens_hsa052141.00296399
56Antigen processing and presentation_Homo sapiens_hsa046121.00063442
57mTOR signaling pathway_Homo sapiens_hsa041500.99550718
58Central carbon metabolism in cancer_Homo sapiens_hsa052300.99036443
59Endocytosis_Homo sapiens_hsa041440.97785125
60Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.97743828
61Osteoclast differentiation_Homo sapiens_hsa043800.97228558
62Melanoma_Homo sapiens_hsa052180.93109685
63Basal cell carcinoma_Homo sapiens_hsa052170.93037510
64Acute myeloid leukemia_Homo sapiens_hsa052210.92821384
65Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.89534291
66Ras signaling pathway_Homo sapiens_hsa040140.88459799
67Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.87100769
68Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85371671
69Legionellosis_Homo sapiens_hsa051340.82956420
70Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.82538837
71Prostate cancer_Homo sapiens_hsa052150.82347230
72Notch signaling pathway_Homo sapiens_hsa043300.82263796
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80359586
74Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.79479833
75Non-small cell lung cancer_Homo sapiens_hsa052230.78882906
76Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.77817974
77Melanogenesis_Homo sapiens_hsa049160.76483730
78Prion diseases_Homo sapiens_hsa050200.76390789
79Hedgehog signaling pathway_Homo sapiens_hsa043400.75410207
80Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75226134
81Pertussis_Homo sapiens_hsa051330.75142679
82Renin-angiotensin system_Homo sapiens_hsa046140.74828863
83Prolactin signaling pathway_Homo sapiens_hsa049170.72221615
84Measles_Homo sapiens_hsa051620.70511340
85Jak-STAT signaling pathway_Homo sapiens_hsa046300.70190939
86AMPK signaling pathway_Homo sapiens_hsa041520.69347062
87Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68565895
88FoxO signaling pathway_Homo sapiens_hsa040680.68554659
89ErbB signaling pathway_Homo sapiens_hsa040120.67643038
90Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.66075847
91Hepatitis C_Homo sapiens_hsa051600.65008945
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64520513
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.63913231
94Epstein-Barr virus infection_Homo sapiens_hsa051690.63799761
95Insulin resistance_Homo sapiens_hsa049310.63662650
96RNA transport_Homo sapiens_hsa030130.63605727
97Tuberculosis_Homo sapiens_hsa051520.63443520
98Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.63177251
99B cell receptor signaling pathway_Homo sapiens_hsa046620.62257949
100Phagosome_Homo sapiens_hsa041450.61833038
101Estrogen signaling pathway_Homo sapiens_hsa049150.61151239
102NF-kappa B signaling pathway_Homo sapiens_hsa040640.60417477
103Toll-like receptor signaling pathway_Homo sapiens_hsa046200.60173483
104Lysosome_Homo sapiens_hsa041420.59857687
105Influenza A_Homo sapiens_hsa051640.59141209
106N-Glycan biosynthesis_Homo sapiens_hsa005100.58909722
107MAPK signaling pathway_Homo sapiens_hsa040100.58633405
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58431576
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.58334311
110Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.55381274
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.54968029
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54738803
113Sphingolipid metabolism_Homo sapiens_hsa006000.54550527
114Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54244398
115Galactose metabolism_Homo sapiens_hsa000520.54147119
116Glycosaminoglycan degradation_Homo sapiens_hsa005310.53412938
117cGMP-PKG signaling pathway_Homo sapiens_hsa040220.53002116
118Hematopoietic cell lineage_Homo sapiens_hsa046400.52243512
119Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52102897
120Vascular smooth muscle contraction_Homo sapiens_hsa042700.50905541
121Wnt signaling pathway_Homo sapiens_hsa043100.50428964
122Insulin signaling pathway_Homo sapiens_hsa049100.49387815
123Gap junction_Homo sapiens_hsa045400.49323778
124Phospholipase D signaling pathway_Homo sapiens_hsa040720.48512848
125Steroid biosynthesis_Homo sapiens_hsa001000.41494890

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