KCTD11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1chondrocyte proliferation (GO:0035988)6.95682775
2desmosome organization (GO:0002934)5.73707845
3wound healing, spreading of epidermal cells (GO:0035313)5.51382402
4skin morphogenesis (GO:0043589)5.45266986
5cell adhesion mediated by integrin (GO:0033627)4.56754861
6wound healing, spreading of cells (GO:0044319)4.56702184
7hemidesmosome assembly (GO:0031581)4.52052039
8keratinization (GO:0031424)4.51144508
9endodermal cell differentiation (GO:0035987)4.25085440
10collagen fibril organization (GO:0030199)4.23224594
11establishment of skin barrier (GO:0061436)4.18097561
12regulation of water loss via skin (GO:0033561)4.12243548
13negative regulation of fatty acid transport (GO:2000192)4.09971441
14dichotomous subdivision of an epithelial terminal unit (GO:0060600)4.09355753
15surfactant homeostasis (GO:0043129)3.94088225
16hypotonic response (GO:0006971)3.87794154
17protein localization to endosome (GO:0036010)3.85126443
18peptide cross-linking (GO:0018149)3.72139059
19keratinocyte differentiation (GO:0030216)3.71605562
20molting cycle (GO:0042303)3.71365693
21hair cycle (GO:0042633)3.71365693
22positive regulation of endothelial cell apoptotic process (GO:2000353)3.69068456
23sequestering of extracellular ligand from receptor (GO:0035581)3.64774090
24planar cell polarity pathway involved in neural tube closure (GO:0090179)3.64550427
25Golgi transport vesicle coating (GO:0048200)3.55599506
26COPI coating of Golgi vesicle (GO:0048205)3.55599506
27regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.48956861
28establishment of tissue polarity (GO:0007164)3.48061679
29establishment of planar polarity (GO:0001736)3.48061679
30craniofacial suture morphogenesis (GO:0097094)3.43127251
31barbed-end actin filament capping (GO:0051016)3.38643996
32regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)3.30231954
33mesodermal cell differentiation (GO:0048333)3.29830052
34cellular response to vitamin D (GO:0071305)3.26998935
35epidermis development (GO:0008544)3.22229034
36epithelial cell-cell adhesion (GO:0090136)3.15110229
37mesenchymal-epithelial cell signaling (GO:0060638)3.13853240
38positive regulation of epidermis development (GO:0045684)3.13851601
39gap junction assembly (GO:0016264)3.13391318
40atrioventricular valve morphogenesis (GO:0003181)3.12258770
41collagen metabolic process (GO:0032963)3.11781701
42focal adhesion assembly (GO:0048041)3.11365948
43cell-substrate adherens junction assembly (GO:0007045)3.11365948
44maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.10014188
45collagen catabolic process (GO:0030574)3.09858375
46vascular endothelial growth factor signaling pathway (GO:0038084)3.05572123
47protein heterotrimerization (GO:0070208)3.05563941
48chemical homeostasis within a tissue (GO:0048875)3.04198304
49adhesion of symbiont to host cell (GO:0044650)3.03824338
50virion attachment to host cell (GO:0019062)3.03824338
51positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.03807727
52positive regulation of osteoblast proliferation (GO:0033690)3.03068323
53multicellular organismal water homeostasis (GO:0050891)3.01847156
54apoptotic cell clearance (GO:0043277)3.00833596
55cellular response to vitamin (GO:0071295)2.98497523
56cell-substrate junction assembly (GO:0007044)2.98013616
57mammary gland epithelial cell proliferation (GO:0033598)2.95508208
58extracellular matrix disassembly (GO:0022617)2.95189611
59adhesion of symbiont to host (GO:0044406)2.95146892
60regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.95017776
61adherens junction assembly (GO:0034333)2.93906953
62epithelial cell differentiation involved in prostate gland development (GO:0060742)2.92526847
63positive regulation of blood vessel endothelial cell migration (GO:0043536)2.91116810
64regulation of hair follicle development (GO:0051797)2.89990029
65positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.88725406
66multicellular organismal macromolecule metabolic process (GO:0044259)2.88263038
67regulation of transforming growth factor beta2 production (GO:0032909)2.87993822
68axonemal dynein complex assembly (GO:0070286)2.87929100
69positive regulation of epidermal cell differentiation (GO:0045606)2.87833977
70multicellular organismal catabolic process (GO:0044243)2.84329392
71lymphangiogenesis (GO:0001946)2.83180207
72regulation of interleukin-8 secretion (GO:2000482)2.82964328
73basement membrane organization (GO:0071711)2.80455714
74keratinocyte proliferation (GO:0043616)2.80029757
75cytoskeletal anchoring at plasma membrane (GO:0007016)2.78939542
76positive regulation of keratinocyte differentiation (GO:0045618)2.78873424
77negative regulation of smooth muscle cell migration (GO:0014912)2.78792177
78glomerular visceral epithelial cell development (GO:0072015)2.78767139
79water homeostasis (GO:0030104)2.77493589
80stress fiber assembly (GO:0043149)2.77459383
81positive regulation of hair cycle (GO:0042635)2.76520305
82positive regulation of hair follicle development (GO:0051798)2.76520305
83substrate-dependent cell migration (GO:0006929)2.76001640
84intermediate filament organization (GO:0045109)2.72211024
85multicellular organismal metabolic process (GO:0044236)2.70829116
86positive regulation of collagen biosynthetic process (GO:0032967)2.68652242
87type B pancreatic cell proliferation (GO:0044342)2.67755582
88neuron projection extension involved in neuron projection guidance (GO:1902284)2.65415558
89axon extension involved in axon guidance (GO:0048846)2.65415558
90epidermal cell differentiation (GO:0009913)2.65389041
91negative regulation of cartilage development (GO:0061037)2.62883043
92lymph vessel development (GO:0001945)2.62763385
93gland morphogenesis (GO:0022612)2.60523798
94protein retention in ER lumen (GO:0006621)2.60453056
95negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.60081776
96glomerular basement membrane development (GO:0032836)2.59980331
97peptidyl-proline hydroxylation (GO:0019511)2.59108849
98positive regulation of p38MAPK cascade (GO:1900745)2.59107001
99retina vasculature morphogenesis in camera-type eye (GO:0061299)2.58865281
100regulation of transforming growth factor beta1 production (GO:0032908)2.57824261
101positive regulation of collagen metabolic process (GO:0010714)2.56651087
102interleukin-1-mediated signaling pathway (GO:0070498)2.55388123
103embryonic cranial skeleton morphogenesis (GO:0048701)2.55124374
104positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.54650968
105positive regulation of Cdc42 GTPase activity (GO:0043089)2.54216858
106polarized epithelial cell differentiation (GO:0030859)2.53037144
107regulation of early endosome to late endosome transport (GO:2000641)2.52477219
108regulation of membrane protein ectodomain proteolysis (GO:0051043)2.52149991
109negative regulation of cell fate specification (GO:0009996)2.51240198
110membrane protein ectodomain proteolysis (GO:0006509)2.50859543
111cell junction assembly (GO:0034329)2.50650421
112hyaluronan catabolic process (GO:0030214)2.49847723
113wound healing (GO:0042060)2.48280718
114regulation of keratinocyte proliferation (GO:0010837)2.48014512
115mesenchymal cell differentiation involved in kidney development (GO:0072161)2.46972046
116mesenchymal cell differentiation involved in renal system development (GO:2001012)2.46972046
117bone trabecula formation (GO:0060346)2.46719420
118response to progesterone (GO:0032570)2.46655790
119regulation of collagen metabolic process (GO:0010712)2.46637471
120regulation of cartilage development (GO:0061035)2.46186747
121regulation of collagen biosynthetic process (GO:0032965)2.46101835
122cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.45334772
123bundle of His cell to Purkinje myocyte communication (GO:0086069)2.44930503
124regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.44892097
125endothelial cell chemotaxis (GO:0035767)2.44800123
126regulation of integrin-mediated signaling pathway (GO:2001044)2.44722366
127amyloid precursor protein catabolic process (GO:0042987)2.44486483
128negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.44469481
129positive regulation of interleukin-8 secretion (GO:2000484)2.44460174
130cell junction organization (GO:0034330)2.44385268
131decidualization (GO:0046697)2.43854913
132extracellular matrix organization (GO:0030198)2.43166741
133positive regulation of cartilage development (GO:0061036)2.43112835
134endocardial cushion development (GO:0003197)2.43015249
135substrate adhesion-dependent cell spreading (GO:0034446)2.42805350
136regulation of monocyte chemotaxis (GO:0090025)2.42794049
137extracellular structure organization (GO:0043062)2.41829710
138sprouting angiogenesis (GO:0002040)2.41792603
139semaphorin-plexin signaling pathway (GO:0071526)2.41278768
140glomerular epithelial cell development (GO:0072310)2.41207837
141protein hydroxylation (GO:0018126)2.40363536
142heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.39919742
143regulation of apoptotic process involved in morphogenesis (GO:1902337)2.39848415
144negative regulation of chondrocyte differentiation (GO:0032331)2.39276957
145metanephric mesenchyme development (GO:0072075)2.37721895
146negative regulation of keratinocyte proliferation (GO:0010839)2.37687462
147detection of molecule of bacterial origin (GO:0032490)2.36759958
148extracellular fibril organization (GO:0043206)2.35240367
149lung vasculature development (GO:0060426)2.35179111
150negative regulation of interferon-gamma production (GO:0032689)2.34529200
151positive regulation of monocyte chemotaxis (GO:0090026)2.33809283
152fibril organization (GO:0097435)2.33669794
153pinocytosis (GO:0006907)2.32543177
154motile cilium assembly (GO:0044458)2.32277341
155Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.32270442
156establishment of apical/basal cell polarity (GO:0035089)2.31928906

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human5.24420141
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.33794492
3RARG_19884340_ChIP-ChIP_MEFs_Mouse3.73273941
4SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.21101191
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.61465110
6ESR1_21235772_ChIP-Seq_MCF-7_Human2.50854523
7PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.46755407
8SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.40810326
9SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.40810326
10CJUN_26792858_Chip-Seq_BT549_Human2.37072563
11TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.30463839
12CLOCK_20551151_ChIP-Seq_293T_Human2.21742871
13FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.21465650
14WT1_19549856_ChIP-ChIP_CCG9911_Human2.13884354
15SMAD_19615063_ChIP-ChIP_OVARY_Human2.10922287
16ZNF263_19887448_ChIP-Seq_K562_Human2.10414754
17LXR_22292898_ChIP-Seq_THP-1_Human2.06131084
18RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.05981728
19P63_26484246_Chip-Seq_KERATINOCYTES_Human2.00795498
20TP63_17297297_ChIP-ChIP_HaCaT_Human10.2575577
21HIF1A_21447827_ChIP-Seq_MCF-7_Human1.94642094
22EGR1_19374776_ChIP-ChIP_THP-1_Human1.87253862
23SOX9_24532713_ChIP-Seq_HFSC_Mouse1.84450422
24GATA2_21666600_ChIP-Seq_HMVEC_Human1.81047989
25SOX2_20726797_ChIP-Seq_SW620_Human1.78441097
26ESR2_21235772_ChIP-Seq_MCF-7_Human1.78193667
27CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.77663580
28RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.77447312
29FOXO3_23340844_ChIP-Seq_DLD1_Human1.76692353
30JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.75135805
31CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.73888875
32BRD4_25478319_ChIP-Seq_HGPS_Human1.73325780
33FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.65533230
34NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.65247040
35ZNF217_24962896_ChIP-Seq_MCF-7_Human1.64566080
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.63259234
37ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.61039362
38JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.58604926
39NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.56236954
40NRF2_20460467_ChIP-Seq_MEFs_Mouse1.56236954
41TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.53489766
42UBF1/2_26484160_Chip-Seq_HMECs_Human1.51872176
43ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.50970733
44ESR1_20079471_ChIP-ChIP_T-47D_Human1.48926245
45TP53_18474530_ChIP-ChIP_U2OS_Human1.47524602
46STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.46979810
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.46098853
48SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.45289686
49ELK3_25401928_ChIP-Seq_HUVEC_Human1.42788060
50KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.42009176
51TP63_22573176_ChIP-Seq_HFKS_Human1.38118675
52EP300_21415370_ChIP-Seq_HL-1_Mouse1.37041149
53KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.36682318
54TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.32575770
55EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.31238994
56KDM2B_26808549_Chip-Seq_K562_Human1.28714535
57TP63_23658742_ChIP-Seq_EP156T_Human1.25542794
58TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24203435
59TP53_20018659_ChIP-ChIP_R1E_Mouse1.22258401
60Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.20555230
61KDM2B_26808549_Chip-Seq_DND41_Human1.20470590
62SMC4_20622854_ChIP-Seq_HELA_Human1.20020203
63* RXR_22108803_ChIP-Seq_LS180_Human1.20008044
64* SA1_27219007_Chip-Seq_ERYTHROID_Human1.19098878
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18518601
66VDR_21846776_ChIP-Seq_THP-1_Human1.18305617
67ATF3_27146783_Chip-Seq_COLON_Human1.16562501
68KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.16357053
69* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.15086977
70PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.14291257
71STAT6_21828071_ChIP-Seq_BEAS2B_Human1.13258165
72RACK7_27058665_Chip-Seq_MCF-7_Human1.10412299
73TCF7_22412390_ChIP-Seq_EML_Mouse1.10129876
74ERG_21242973_ChIP-ChIP_JURKAT_Human1.09196096
75STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.08568980
76KLF5_25053715_ChIP-Seq_YYC3_Human1.08385198
77ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.06254304
78TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.05472517
79SRY_22984422_ChIP-ChIP_TESTIS_Rat1.04817291
80CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.03792977
81CDX2_20551321_ChIP-Seq_CACO-2_Human1.03378502
82SALL4_18804426_ChIP-ChIP_XEN_Mouse1.02838861
83* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.02757330
84FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.02386263
85SOX2_27498859_Chip-Seq_STOMACH_Mouse1.01163963
86CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.00394310
87MYB_21317192_ChIP-Seq_ERMYB_Mouse0.99580762
88TCF4_18268006_ChIP-ChIP_LS174T_Human0.98632506
89VDR_24787735_ChIP-Seq_THP-1_Human0.98622368
90CTCF_27219007_Chip-Seq_Bcells_Human0.98582540
91* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.98548951
92TP53_16413492_ChIP-PET_HCT116_Human0.98536248
93GATA3_24758297_ChIP-Seq_MCF-7_Human0.97990440
94ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.97666119
95VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.97583009
96UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.97029270
97VDR_24763502_ChIP-Seq_THP-1_Human0.96195492
98STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.95774470
99TBX20_22080862_ChIP-Seq_HEART_Mouse0.95521049
100TBX20_22328084_ChIP-Seq_HEART_Mouse0.95521049
101FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.95360356
102CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.95177323
103ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94718381
104AHR_22903824_ChIP-Seq_MCF-7_Human0.94306674
105P300_27058665_Chip-Seq_ZR-75-30cells_Human0.94181431
106FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.93741579
107* SMC1_22415368_ChIP-Seq_MEFs_Mouse0.93522589
108CTCF_27219007_Chip-Seq_ERYTHROID_Human0.93481111
109ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93447641
110CREB1_26743006_Chip-Seq_LNCaP_Human0.93061443
111P68_20966046_ChIP-Seq_HELA_Human0.92939294
112* TP53_23651856_ChIP-Seq_MEFs_Mouse0.92451355
113* TET1_21490601_ChIP-Seq_MESCs_Mouse0.91811904
114NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.90973035
115* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.90791092
116ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.90525018
117BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.89724091
118KDM2B_26808549_Chip-Seq_JURKAT_Human0.87578224
119ARNT_22903824_ChIP-Seq_MCF-7_Human0.87554409
120STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.87362608
121RUNX1_27514584_Chip-Seq_MCF-7_Human0.87203945
122SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86266972
123* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.85975954
124CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.85768617
125GATA4_25053715_ChIP-Seq_YYC3_Human0.85733117
126SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.84641083
127SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.83553061
128* TET1_21451524_ChIP-Seq_MESCs_Mouse0.82356212
129TP53_22127205_ChIP-Seq_IMR90_Human0.82293003
130* SMC3_22415368_ChIP-Seq_MEFs_Mouse0.81936714
131RXR_22158963_ChIP-Seq_LIVER_Mouse0.81704092
132ELK1_22589737_ChIP-Seq_MCF10A_Human0.80732304
133ELF1_20517297_ChIP-Seq_JURKAT_Human0.80713162
134HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.79666880
135* BCOR_27268052_Chip-Seq_Bcells_Human0.78832890
136EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.78316203
137KDM2B_26808549_Chip-Seq_SUP-B15_Human0.77740461
138NFIB_24661679_ChIP-Seq_LUNG_Mouse0.77694077
139EED_16625203_ChIP-ChIP_MESCs_Mouse0.77403883
140ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.74525841
141SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.71809092
142* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.71386544

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005275_abnormal_skin_tensile5.22248895
2MP0008438_abnormal_cutaneous_collagen4.98109211
3MP0003705_abnormal_hypodermis_morpholog3.61243850
4MP0003566_abnormal_cell_adhesion3.07590095
5MP0003279_aneurysm2.85162102
6MP0002796_impaired_skin_barrier2.79478293
7MP0010352_gastrointestinal_tract_polyps2.71732045
8MP0002060_abnormal_skin_morphology2.71316048
9MP0006054_spinal_hemorrhage2.66569301
10MP0005503_abnormal_tendon_morphology2.65910388
11MP0001849_ear_inflammation2.37361887
12MP0003941_abnormal_skin_development2.33326594
13MP0002877_abnormal_melanocyte_morpholog2.27749875
14MP0004272_abnormal_basement_membrane2.24501502
15MP0005023_abnormal_wound_healing2.16113194
16MP0005623_abnormal_meninges_morphology2.11443755
17MP0005257_abnormal_intraocular_pressure2.08005207
18MP0005501_abnormal_skin_physiology2.07835310
19MP0001958_emphysema2.00006817
20MP0001243_abnormal_dermal_layer1.86901011
21MP0008004_abnormal_stomach_pH1.85376467
22MP0009384_cardiac_valve_regurgitation1.83466522
23MP0009840_abnormal_foam_cell1.82648241
24MP0005508_abnormal_skeleton_morphology1.72899580
25MP0003453_abnormal_keratinocyte_physiol1.72122876
26MP0000579_abnormal_nail_morphology1.67307462
27MP0003300_gastrointestinal_ulcer1.66444526
28MP0001216_abnormal_epidermal_layer1.63577491
29MP0009780_abnormal_chondrocyte_physiolo1.62234766
30MP0003091_abnormal_cell_migration1.60883837
31MP0008260_abnormal_autophagy1.60465245
32MP0010771_integument_phenotype1.59348746
33MP0010234_abnormal_vibrissa_follicle1.59169216
34MP0002896_abnormal_bone_mineralization1.52693222
35MP0001542_abnormal_bone_strength1.47196511
36MP0005058_abnormal_lysosome_morphology1.47195036
37MP0004947_skin_inflammation1.43034194
38MP0004264_abnormal_extraembryonic_tissu1.42389573
39MP0004381_abnormal_hair_follicle1.41387221
40MP0003045_fibrosis1.40502544
41MP0001879_abnormal_lymphatic_vessel1.39336648
42MP0002098_abnormal_vibrissa_morphology1.37962631
43MP0000383_abnormal_hair_follicle1.37483437
44MP0002295_abnormal_pulmonary_circulatio1.36271554
45MP0010030_abnormal_orbit_morphology1.35598868
46MP0000467_abnormal_esophagus_morphology1.35046277
47MP0005390_skeleton_phenotype1.34768665
48MP0000767_abnormal_smooth_muscle1.31280019
49MP0001533_abnormal_skeleton_physiology1.27105642
50MP0000013_abnormal_adipose_tissue1.25046378
51MP0010368_abnormal_lymphatic_system1.24017658
52MP0009053_abnormal_anal_canal1.19426367
53MP0000762_abnormal_tongue_morphology1.18862792
54MP0005367_renal/urinary_system_phenotyp1.16944596
55MP0000516_abnormal_urinary_system1.16944596
56MP0000377_abnormal_hair_follicle1.14991285
57MP0003385_abnormal_body_wall1.14495305
58MP0004782_abnormal_surfactant_physiolog1.12920143
59MP0005451_abnormal_body_composition1.12355196
60MP0002933_joint_inflammation1.09798853
61MP0000427_abnormal_hair_cycle1.09594111
62MP0010678_abnormal_skin_adnexa1.09499710
63MP0001191_abnormal_skin_condition1.09306402
64MP0004858_abnormal_nervous_system1.09141387
65MP0002998_abnormal_bone_remodeling1.09046475
66MP0000858_altered_metastatic_potential1.07448821
67MP0009250_abnormal_appendicular_skeleto1.02437761
68MP0002234_abnormal_pharynx_morphology1.00612377
69MP0003950_abnormal_plasma_membrane1.00031905
70MP0009931_abnormal_skin_appearance0.99493350
71MP0000537_abnormal_urethra_morphology0.99072482
72MP0000163_abnormal_cartilage_morphology0.97454042
73MP0002177_abnormal_outer_ear0.95551300
74MP0000647_abnormal_sebaceous_gland0.95308792
75MP0000733_abnormal_muscle_development0.91506518
76MP0003828_pulmonary_edema0.90921200
77MP0003795_abnormal_bone_structure0.90848084
78MP0000750_abnormal_muscle_regeneration0.90636103
79MP0002168_other_aberrant_phenotype0.90129542
80MP0002282_abnormal_trachea_morphology0.88133824
81MP0002115_abnormal_skeleton_extremities0.86954041
82MP0003448_altered_tumor_morphology0.86935845
83MP0001348_abnormal_lacrimal_gland0.86915095
84MP0002113_abnormal_skeleton_development0.84388621
85MP0003755_abnormal_palate_morphology0.83864841
86MP0000003_abnormal_adipose_tissue0.82483152
87MP0005076_abnormal_cell_differentiation0.81541507
88MP0003436_decreased_susceptibility_to0.81505734
89MP0003942_abnormal_urinary_system0.79464045
90MP0003303_peritoneal_inflammation0.78783352
91MP0000627_abnormal_mammary_gland0.77916056
92MP0003724_increased_susceptibility_to0.77190539
93MP0000343_altered_response_to0.77143689
94MP0003878_abnormal_ear_physiology0.75685773
95MP0005377_hearing/vestibular/ear_phenot0.75685773
96MP0000751_myopathy0.75333230
97MP0000534_abnormal_ureter_morphology0.75254077
98MP0001614_abnormal_blood_vessel0.73318246
99MP0001851_eye_inflammation0.73167531
100MP0003191_abnormal_cellular_cholesterol0.72442965
101MP0002254_reproductive_system_inflammat0.70614335
102MP0005248_abnormal_Harderian_gland0.70401499
103MP0001346_abnormal_lacrimal_gland0.69767866
104MP0001299_abnormal_eye_distance/0.69230754
105MP0005165_increased_susceptibility_to0.68931268
106MP0005164_abnormal_response_to0.68412875
107MP0005409_darkened_coat_color0.67235878
108MP0002109_abnormal_limb_morphology0.66493900
109MP0000678_abnormal_parathyroid_gland0.65593606
110MP0004510_myositis0.64846752
111MP0002925_abnormal_cardiovascular_devel0.64361251
112MP0003329_amyloid_beta_deposits0.63907209
113MP0000566_synostosis0.63344685
114MP0000367_abnormal_coat/_hair0.61656272
115MP0005197_abnormal_uvea_morphology0.60375462
116MP0000465_gastrointestinal_hemorrhage0.60131422
117MP0002932_abnormal_joint_morphology0.60082364
118MP0004233_abnormal_muscle_weight0.58814436
119MP0008789_abnormal_olfactory_epithelium0.58780734
120MP0005193_abnormal_anterior_eye0.57144131
121MP0003075_altered_response_to0.56774807
122MP0002089_abnormal_postnatal_growth/wei0.54259647
123MP0000685_abnormal_immune_system0.54116605
124MP0003315_abnormal_perineum_morphology0.53538788
125MP0000538_abnormal_urinary_bladder0.52891304
126MP0001340_abnormal_eyelid_morphology0.52588237

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)6.89477892
2Protrusio acetabuli (HP:0003179)5.71680903
3Atrophic scars (HP:0001075)5.23441223
4Aortic dissection (HP:0002647)4.11577371
5Fragile skin (HP:0001030)4.03769969
6Peritonitis (HP:0002586)3.88172743
7Right ventricular cardiomyopathy (HP:0011663)3.71363910
8Follicular hyperkeratosis (HP:0007502)3.67095187
9Soft skin (HP:0000977)3.64129194
10Alopecia of scalp (HP:0002293)3.52010891
11Cervical subluxation (HP:0003308)3.42538808
12Shallow orbits (HP:0000586)3.20581125
13Cerebral aneurysm (HP:0004944)3.17573461
14Onycholysis (HP:0001806)3.08591507
15Dilatation of the ascending aorta (HP:0005111)3.02179479
16Aortic aneurysm (HP:0004942)2.98653311
17Milia (HP:0001056)2.96601994
18Ridged nail (HP:0001807)2.95762259
19Plantar hyperkeratosis (HP:0007556)2.91157389
20Wormian bones (HP:0002645)2.79921166
21Vertebral compression fractures (HP:0002953)2.79227757
22Abnormality of dentin (HP:0010299)2.76379587
23Increased connective tissue (HP:0009025)2.72842672
24Pili torti (HP:0003777)2.72827842
25Hypotrichosis (HP:0001006)2.66078107
26Palmoplantar hyperkeratosis (HP:0000972)2.60134216
27Blue sclerae (HP:0000592)2.55639522
28Mitral valve prolapse (HP:0001634)2.52424819
29Short nail (HP:0001799)2.46409271
30Abnormality of nail color (HP:0100643)2.45804029
31Oral leukoplakia (HP:0002745)2.44580396
32Increased IgE level (HP:0003212)2.42672074
33Spinal rigidity (HP:0003306)2.42141084
34Bladder diverticulum (HP:0000015)2.40791195
35Thick nail (HP:0001805)2.40574850
36Distal lower limb amyotrophy (HP:0008944)2.39373160
37Biconcave vertebral bodies (HP:0004586)2.38804836
38Palmar hyperkeratosis (HP:0010765)2.38792642
39Genu recurvatum (HP:0002816)2.38619341
40Neonatal short-limb short stature (HP:0008921)2.36828700
41Osteolytic defects of the hand bones (HP:0009699)2.33795177
42Osteolytic defects of the phalanges of the hand (HP:0009771)2.33795177
43Nasal polyposis (HP:0100582)2.32191967
44Ankle contracture (HP:0006466)2.31666856
45Natal tooth (HP:0000695)2.29874282
46Distal lower limb muscle weakness (HP:0009053)2.27440090
47Type 1 muscle fiber predominance (HP:0003803)2.25095122
48Abnormality of the nasal mucosa (HP:0000433)2.24931485
49Broad metatarsal (HP:0001783)2.23270850
50Woolly hair (HP:0002224)2.23222479
51Abnormal hair laboratory examination (HP:0003328)2.23121690
52Popliteal pterygium (HP:0009756)2.20588988
53Selective tooth agenesis (HP:0001592)2.19217157
54Spinal cord lesions (HP:0100561)2.18296018
55Syringomyelia (HP:0003396)2.18296018
56Hypoplasia of dental enamel (HP:0006297)2.17655807
57Spondylolisthesis (HP:0003302)2.13121769
58Elbow flexion contracture (HP:0002987)2.11123728
59Ectopia lentis (HP:0001083)2.10742657
60Vascular tortuosity (HP:0004948)2.08759994
61Unilateral renal agenesis (HP:0000122)2.08707894
62Abnormality of liposaccharide metabolism (HP:0010968)2.07920201
63Abnormality of glycosphingolipid metabolism (HP:0004343)2.07920201
64Abnormality of glycolipid metabolism (HP:0010969)2.07920201
65Erythema (HP:0010783)2.07471741
66Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.07369947
67Congenital ichthyosiform erythroderma (HP:0007431)2.06090660
68Round ear (HP:0100830)2.05844200
69Lip pit (HP:0100267)2.04313972
70Hyperacusis (HP:0010780)2.01422691
71Abnormality of the acetabulum (HP:0003170)2.01279806
72Abnormality of the distal phalanges of the toes (HP:0010182)2.00582944
73Parakeratosis (HP:0001036)1.99094147
74Axonal loss (HP:0003447)1.99083041
75Abnormality of the calcaneus (HP:0008364)1.97652218
76Advanced eruption of teeth (HP:0006288)1.96507495
77Scapular winging (HP:0003691)1.96191844
78Wrist flexion contracture (HP:0001239)1.96026432
79Arterial tortuosity (HP:0005116)1.95538235
80Fragile nails (HP:0001808)1.95070242
81Overgrowth (HP:0001548)1.94281788
82Hyperextensible skin (HP:0000974)1.93978108
83Nonimmune hydrops fetalis (HP:0001790)1.93096135
84Aneurysm (HP:0002617)1.91813839
85Thin bony cortex (HP:0002753)1.91180164
86Nail dystrophy (HP:0008404)1.90300865
87Tibial bowing (HP:0002982)1.88560840
88Platyspondyly (HP:0000926)1.88441299
89Femoral bowing (HP:0002980)1.88111473
90Achilles tendon contracture (HP:0001771)1.86652178
91Absent eyelashes (HP:0000561)1.85955054
92Pterygium (HP:0001059)1.85770336
93Camptodactyly of toe (HP:0001836)1.85735071
94Mesomelia (HP:0003027)1.84999187
95Ankyloglossia (HP:0010296)1.84980704
96Sparse scalp hair (HP:0002209)1.84451543
97Abnormal delivery (HP:0001787)1.84257814
98Joint stiffness (HP:0001387)1.82120867
99Palmoplantar keratoderma (HP:0000982)1.80212359
100Carious teeth (HP:0000670)1.80205238
101Dysostosis multiplex (HP:0000943)1.78842138
102Craniofacial hyperostosis (HP:0004493)1.78218322
103Flat acetabular roof (HP:0003180)1.77923670
104Distal upper limb amyotrophy (HP:0007149)1.77703655
105Upper limb amyotrophy (HP:0009129)1.77703655
106Conjunctival hamartoma (HP:0100780)1.77575779
107Asymmetric septal hypertrophy (HP:0001670)1.77558574
108Corneal erosion (HP:0200020)1.76375089
109Abnormality of the peritoneum (HP:0002585)1.74353173
110Mitral regurgitation (HP:0001653)1.74118330
111Premature loss of primary teeth (HP:0006323)1.71417237
112Back pain (HP:0003418)1.70140504
113Abnormal blistering of the skin (HP:0008066)1.69350032
114Rhinitis (HP:0012384)1.69168044
115Joint laxity (HP:0001388)1.68778618
116Beaking of vertebral bodies (HP:0004568)1.68683779
117Abnormality of oral frenula (HP:0000190)1.68610722
118Corneal dystrophy (HP:0001131)1.68589467
119Increased density of long bones (HP:0006392)1.68507489
120Acanthosis nigricans (HP:0000956)1.66310084
121Mitral stenosis (HP:0001718)1.65909085
122Mildly elevated creatine phosphokinase (HP:0008180)1.65712429
123Broad face (HP:0000283)1.65710749
124Aplasia cutis congenita (HP:0001057)1.65455073
125Ectropion (HP:0000656)1.65373274
126Xerostomia (HP:0000217)1.64931227
127Curly hair (HP:0002212)1.64699948
128Abnormality of the odontoid process (HP:0003310)1.64112526
129Neurofibrillary tangles (HP:0002185)1.63907599
130Decreased skull ossification (HP:0004331)1.63869743
131Abnormality of the salivary glands (HP:0010286)1.63357291
132Sparse eyelashes (HP:0000653)1.63086653
133Mucopolysacchariduria (HP:0008155)1.62703441
134Venous abnormality (HP:0002624)1.60471089
135Ventricular tachycardia (HP:0004756)1.58127660
136Difficulty climbing stairs (HP:0003551)1.57728954
137Knee flexion contracture (HP:0006380)1.57705661
138Abnormality of skull ossification (HP:0002703)1.57314649
139Anhidrosis (HP:0000970)1.57185870
140Ulnar bowing (HP:0003031)1.56999728

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA33.98289777
2EPHA23.90369144
3LATS13.32967725
4TTN3.03719166
5TRIB32.91677114
6ERN12.88727131
7PIM22.65573878
8ARAF2.50242069
9PRPF4B2.36937828
10TAOK22.34505320
11FER2.31696553
12MAP3K32.23365325
13PIK3CG2.10965818
14EPHB22.03783887
15TGFBR21.96562420
16SMG11.96304602
17EPHB11.91812607
18TRPM71.85085938
19DDR21.79763782
20PTK21.73130668
21CDC42BPA1.72095459
22NEK91.67054955
23MAP3K131.66296752
24RPS6KA41.60757533
25NME21.55732791
26TESK11.55334581
27PDGFRA1.49053601
28INSRR1.48692237
29SIK11.46841288
30ICK1.46125450
31NTRK11.43185811
32PAK41.42344840
33STK381.37556211
34RIPK11.34190861
35PTK61.30117919
36MAP2K31.29716081
37MET1.27317223
38STK241.22858419
39MAPKAPK31.21802249
40MAP3K91.21300526
41BRD41.20578331
42CDK121.19604849
43STK101.19226778
44KSR21.19117141
45IRAK31.16754676
46PAK31.10992754
47BMX1.10767715
48MST41.09994648
49TESK21.07834619
50PRKD21.06774689
51MAPK151.05566085
52ERBB31.04857940
53PAK21.03659041
54JAK31.03503556
55SIK31.01152478
56MYLK1.01112994
57DMPK1.00285057
58LIMK11.00183926
59LMTK20.98395900
60MST1R0.97669072
61MAP3K60.96375384
62STK38L0.96340190
63FGFR10.94812598
64MAP3K140.94614619
65NLK0.93498170
66STK30.92752005
67NUAK10.90642003
68TAOK10.90310699
69FGFR40.90157538
70LRRK20.85298431
71EEF2K0.84627390
72MAP3K10.84406912
73ABL20.83623184
74TBK10.79873095
75CHUK0.78657117
76IKBKB0.71702431
77MAPKAPK20.70273201
78PRKG20.69809241
79PIK3CA0.69787244
80LATS20.67941739
81ROCK20.67775501
82PTK2B0.67597769
83PDPK10.65438220
84MOS0.64245042
85MAP2K20.63322297
86BRAF0.63269382
87CDK60.61594485
88JAK10.61022768
89MAP3K80.59324979
90TGFBR10.59252223
91FRK0.58712090
92HIPK20.58266154
93MAP2K10.57864917
94DYRK1B0.56911134
95ITK0.56535058
96MAP3K20.56257794
97PDGFRB0.55836579
98CSK0.55634300
99RPS6KA20.55504130
100KIT0.53708998
101INSR0.53561953
102TEC0.53321474
103FGFR30.53237863
104RET0.53010485
105CASK0.52190096
106MARK20.51098537
107PASK0.50347602
108MAP3K70.49674773
109KDR0.49527680
110MAP3K110.49451250
111RPS6KA60.47536144
112PKN20.47455163
113ROCK10.47021738
114TIE10.46580224
115BLK0.45962338
116RPS6KL10.45002392
117RPS6KC10.45002392
118MTOR0.43422058
119ILK0.42430985
120MAP3K120.41688585
121FLT30.41624824
122DAPK30.41521911
123HCK0.41036936
124IRAK10.40654070
125GRK60.39822469
126SRC0.38919704
127ZAP700.37207829
128ERBB40.34966301
129WNK10.34641246
130CDK90.34528088
131BCR0.34524836
132ERBB20.34042220
133GRK70.33592835
134FGR0.32895468
135PRKCE0.32822515
136CDK80.32772925
137MKNK10.32130044

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.31095096
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.60438348
3Focal adhesion_Homo sapiens_hsa045102.34385863
4Bladder cancer_Homo sapiens_hsa052192.23835071
5Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.03461390
6Malaria_Homo sapiens_hsa051442.00838683
7Proteoglycans in cancer_Homo sapiens_hsa052051.99768166
8Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.88920461
9AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.83530095
10Adherens junction_Homo sapiens_hsa045201.82308858
11Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.79918963
12Amoebiasis_Homo sapiens_hsa051461.76937133
13Small cell lung cancer_Homo sapiens_hsa052221.76446122
14Leishmaniasis_Homo sapiens_hsa051401.65219557
15MicroRNAs in cancer_Homo sapiens_hsa052061.58737242
16Leukocyte transendothelial migration_Homo sapiens_hsa046701.58231571
17Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.57071888
18p53 signaling pathway_Homo sapiens_hsa041151.51153420
19Shigellosis_Homo sapiens_hsa051311.46731682
20Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.46492295
21Phagosome_Homo sapiens_hsa041451.45057374
22Hippo signaling pathway_Homo sapiens_hsa043901.44166033
23Phenylalanine metabolism_Homo sapiens_hsa003601.43382302
24Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.42292750
25Toxoplasmosis_Homo sapiens_hsa051451.40180433
26TNF signaling pathway_Homo sapiens_hsa046681.39058759
27Chronic myeloid leukemia_Homo sapiens_hsa052201.37236126
28Central carbon metabolism in cancer_Homo sapiens_hsa052301.34304150
29Glycosaminoglycan degradation_Homo sapiens_hsa005311.34193199
30TGF-beta signaling pathway_Homo sapiens_hsa043501.30727244
31Other glycan degradation_Homo sapiens_hsa005111.30457925
32PI3K-Akt signaling pathway_Homo sapiens_hsa041511.30182780
33Pertussis_Homo sapiens_hsa051331.29147482
34Galactose metabolism_Homo sapiens_hsa000521.27893106
35Maturity onset diabetes of the young_Homo sapiens_hsa049501.27024025
36Dilated cardiomyopathy_Homo sapiens_hsa054141.26577195
37Sphingolipid metabolism_Homo sapiens_hsa006001.24800056
38Melanoma_Homo sapiens_hsa052181.22540881
39Regulation of actin cytoskeleton_Homo sapiens_hsa048101.22393758
40Hematopoietic cell lineage_Homo sapiens_hsa046401.19599969
41Protein digestion and absorption_Homo sapiens_hsa049741.17199176
42Prion diseases_Homo sapiens_hsa050201.16444206
43Lysosome_Homo sapiens_hsa041421.16393951
44Pancreatic cancer_Homo sapiens_hsa052121.13950287
45Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.13594560
46Rheumatoid arthritis_Homo sapiens_hsa053231.12205632
47Osteoclast differentiation_Homo sapiens_hsa043801.09758098
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.06866639
49Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.04706618
50Basal cell carcinoma_Homo sapiens_hsa052171.03615981
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.03328972
52Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.02291410
53Apoptosis_Homo sapiens_hsa042101.01247516
54Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.00437460
55Vibrio cholerae infection_Homo sapiens_hsa051100.99302114
56Salmonella infection_Homo sapiens_hsa051320.98117192
57Rap1 signaling pathway_Homo sapiens_hsa040150.95375408
58Protein export_Homo sapiens_hsa030600.95207085
59Fructose and mannose metabolism_Homo sapiens_hsa000510.94679914
60Platelet activation_Homo sapiens_hsa046110.94150970
61Pentose phosphate pathway_Homo sapiens_hsa000300.92430416
62Tuberculosis_Homo sapiens_hsa051520.91310857
63Toll-like receptor signaling pathway_Homo sapiens_hsa046200.91101727
64Legionellosis_Homo sapiens_hsa051340.90959980
65Hepatitis B_Homo sapiens_hsa051610.90324332
66HTLV-I infection_Homo sapiens_hsa051660.90040269
67Hedgehog signaling pathway_Homo sapiens_hsa043400.88433179
68Jak-STAT signaling pathway_Homo sapiens_hsa046300.88281245
69Pathways in cancer_Homo sapiens_hsa052000.87590443
70Tight junction_Homo sapiens_hsa045300.87313579
71Prostate cancer_Homo sapiens_hsa052150.87105205
72Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.83836261
73Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.82592522
74Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.82045313
75Acute myeloid leukemia_Homo sapiens_hsa052210.81832032
76N-Glycan biosynthesis_Homo sapiens_hsa005100.80834578
77Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.80548406
78NF-kappa B signaling pathway_Homo sapiens_hsa040640.78573836
79Axon guidance_Homo sapiens_hsa043600.76627158
80Renal cell carcinoma_Homo sapiens_hsa052110.75997848
81Insulin signaling pathway_Homo sapiens_hsa049100.75924048
82Prolactin signaling pathway_Homo sapiens_hsa049170.74995003
83VEGF signaling pathway_Homo sapiens_hsa043700.74262258
84Viral myocarditis_Homo sapiens_hsa054160.74106819
85GnRH signaling pathway_Homo sapiens_hsa049120.72967057
86Ras signaling pathway_Homo sapiens_hsa040140.70620925
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.68493267
88Non-small cell lung cancer_Homo sapiens_hsa052230.68312204
89Measles_Homo sapiens_hsa051620.67662556
90Arachidonic acid metabolism_Homo sapiens_hsa005900.67337041
91Transcriptional misregulation in cancer_Homo sapiens_hsa052020.67282917
92HIF-1 signaling pathway_Homo sapiens_hsa040660.66835416
93Mineral absorption_Homo sapiens_hsa049780.66550944
94Hepatitis C_Homo sapiens_hsa051600.65655110
95Antigen processing and presentation_Homo sapiens_hsa046120.64753983
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64705278
97Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.64571026
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.63843511
99Notch signaling pathway_Homo sapiens_hsa043300.63193909
100Wnt signaling pathway_Homo sapiens_hsa043100.61687483
101Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.61158130
102Glioma_Homo sapiens_hsa052140.61000511
103Phospholipase D signaling pathway_Homo sapiens_hsa040720.60226629
104Neurotrophin signaling pathway_Homo sapiens_hsa047220.59950660
105NOD-like receptor signaling pathway_Homo sapiens_hsa046210.58706103
106Adipocytokine signaling pathway_Homo sapiens_hsa049200.57737317
107FoxO signaling pathway_Homo sapiens_hsa040680.57455503
108Insulin resistance_Homo sapiens_hsa049310.57070133
109Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.56867665
110Endometrial cancer_Homo sapiens_hsa052130.56724812
111RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.56585215
112Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55919078
113Endocytosis_Homo sapiens_hsa041440.54796932
114mTOR signaling pathway_Homo sapiens_hsa041500.53121152
115Estrogen signaling pathway_Homo sapiens_hsa049150.52939529
116Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52728376
117Viral carcinogenesis_Homo sapiens_hsa052030.52326421
118Thyroid cancer_Homo sapiens_hsa052160.51102045
119Melanogenesis_Homo sapiens_hsa049160.50175161
120Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.50053854
121Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.49962089
122Influenza A_Homo sapiens_hsa051640.49151201
123Choline metabolism in cancer_Homo sapiens_hsa052310.48870688
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.48336946
125ErbB signaling pathway_Homo sapiens_hsa040120.48289114
126Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47989460
127Tyrosine metabolism_Homo sapiens_hsa003500.47659140

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