KCTD17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD)-containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)5.67803612
2locomotory exploration behavior (GO:0035641)5.56709760
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.18051366
4regulation of synapse structural plasticity (GO:0051823)5.04899676
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.02288724
6positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.87773057
7vocalization behavior (GO:0071625)4.69855869
8synaptic vesicle docking involved in exocytosis (GO:0016081)4.69000856
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.53976009
10layer formation in cerebral cortex (GO:0021819)4.50249158
11synaptic vesicle exocytosis (GO:0016079)4.38848714
12glutamate secretion (GO:0014047)4.31892089
13regulation of glutamate receptor signaling pathway (GO:1900449)4.24495078
14regulation of long-term neuronal synaptic plasticity (GO:0048169)4.19536522
15regulation of synaptic vesicle exocytosis (GO:2000300)4.15192489
16regulation of neuronal synaptic plasticity (GO:0048168)4.12138504
17dendritic spine morphogenesis (GO:0060997)4.07893874
18exploration behavior (GO:0035640)3.89165325
19neuromuscular process controlling balance (GO:0050885)3.87128418
20prepulse inhibition (GO:0060134)3.84124952
21amino acid import (GO:0043090)3.80926569
22neurotransmitter secretion (GO:0007269)3.75765060
23activation of protein kinase A activity (GO:0034199)3.72148914
24protein localization to synapse (GO:0035418)3.70099445
25regulation of dendritic spine morphogenesis (GO:0061001)3.68570063
26membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.67897233
27auditory behavior (GO:0031223)3.67547078
28L-amino acid import (GO:0043092)3.65694772
29sodium ion export (GO:0071436)3.60194081
30neuronal action potential propagation (GO:0019227)3.59983350
31protein retention in ER lumen (GO:0006621)3.59592087
32regulation of synaptic vesicle transport (GO:1902803)3.58981381
33ionotropic glutamate receptor signaling pathway (GO:0035235)3.53228481
34positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.52472473
35proline transport (GO:0015824)3.51789107
36cerebellar granule cell differentiation (GO:0021707)3.49313284
37protein localization to endosome (GO:0036010)3.46485403
38cytoskeletal anchoring at plasma membrane (GO:0007016)3.45866411
39neurotransmitter-gated ion channel clustering (GO:0072578)3.44627283
40barbed-end actin filament capping (GO:0051016)3.41716488
41positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.41271723
42cellular potassium ion homeostasis (GO:0030007)3.37289658
43positive regulation of synapse maturation (GO:0090129)3.33490663
44G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.29474063
45response to auditory stimulus (GO:0010996)3.26337757
46gamma-aminobutyric acid transport (GO:0015812)3.25892512
47synaptic transmission, glutamatergic (GO:0035249)3.25791404
48long-term memory (GO:0007616)3.25451315
49regulation of excitatory postsynaptic membrane potential (GO:0060079)3.23941678
50positive regulation of membrane potential (GO:0045838)3.21786334
51regulation of synaptic plasticity (GO:0048167)3.21396899
52glycine transport (GO:0015816)3.20736340
53positive regulation of synaptic transmission, GABAergic (GO:0032230)3.19633063
54regulation of early endosome to late endosome transport (GO:2000641)3.19368300
55cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.18442553
56neuron-neuron synaptic transmission (GO:0007270)3.17005748
57cell communication by electrical coupling (GO:0010644)3.16632360
58dopamine receptor signaling pathway (GO:0007212)3.16160377
59neuronal ion channel clustering (GO:0045161)3.15887174
60dendrite morphogenesis (GO:0048813)3.15251436
61maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.12765190
62regulation of synapse maturation (GO:0090128)3.08191542
63neuron cell-cell adhesion (GO:0007158)3.04271166
64establishment of nucleus localization (GO:0040023)3.02573660
65adenosine receptor signaling pathway (GO:0001973)3.02517608
66cell migration in hindbrain (GO:0021535)3.02392085
67regulation of postsynaptic membrane potential (GO:0060078)3.02030275
68dendritic spine organization (GO:0097061)3.01827574
69postsynaptic membrane organization (GO:0001941)3.01085306
70glutamate receptor signaling pathway (GO:0007215)3.00743319
71adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.97855494
72regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.97264797
73positive regulation of neurotransmitter transport (GO:0051590)2.94737933
74regulation of synaptic transmission, glutamatergic (GO:0051966)2.94288417
75cerebellar Purkinje cell layer development (GO:0021680)2.93078623
76negative regulation of cytosolic calcium ion concentration (GO:0051481)2.92817666
77positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.92431703
78regulation of dendritic spine development (GO:0060998)2.90560915
79negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.90037444
80transmission of nerve impulse (GO:0019226)2.89654758
81positive regulation of fibroblast migration (GO:0010763)2.89369071
82neuromuscular process (GO:0050905)2.88832670
83mating behavior (GO:0007617)2.88385761
84neuromuscular process controlling posture (GO:0050884)2.86900849
85regulation of ARF GTPase activity (GO:0032312)2.86126762
86regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.85640906
87cell-cell junction maintenance (GO:0045217)2.84844251
88neurotransmitter transport (GO:0006836)2.84779864
89synaptic transmission, dopaminergic (GO:0001963)2.83658230
90striatum development (GO:0021756)2.81365499
91membrane hyperpolarization (GO:0060081)2.81076011
92regulation of voltage-gated calcium channel activity (GO:1901385)2.80545695
93positive regulation of protein dephosphorylation (GO:0035307)2.80208926
94plasma membrane repair (GO:0001778)2.79421684
95stress fiber assembly (GO:0043149)2.77352106
96regulation of ARF protein signal transduction (GO:0032012)2.76943252
97synaptic vesicle endocytosis (GO:0048488)2.76764314
98positive regulation of dendritic spine development (GO:0060999)2.76709931
99neuron recognition (GO:0008038)2.76594877
100axonal fasciculation (GO:0007413)2.76402269
101cerebellar Purkinje cell differentiation (GO:0021702)2.74446471
102regulation of neurotransmitter secretion (GO:0046928)2.73719996
103positive regulation of dendritic spine morphogenesis (GO:0061003)2.73318732
104regulation of mammary gland epithelial cell proliferation (GO:0033599)2.73041585
105long-term synaptic potentiation (GO:0060291)2.72786916
106vesicle transport along microtubule (GO:0047496)2.72473227
107membrane depolarization during action potential (GO:0086010)2.72416672
108regulation of neurotransmitter levels (GO:0001505)2.72368187
109regulation of vesicle fusion (GO:0031338)2.70314844
110positive regulation of neurotransmitter secretion (GO:0001956)2.70057397
111establishment of mitochondrion localization (GO:0051654)2.68738580
112regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.67940017
113protein targeting to plasma membrane (GO:0072661)2.67807544
114membrane depolarization (GO:0051899)2.67383134
115cAMP biosynthetic process (GO:0006171)2.66933993
116adherens junction assembly (GO:0034333)2.66248718
117regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.66007324
118regulation of neurotransmitter transport (GO:0051588)2.65834891
119negative regulation of dendrite morphogenesis (GO:0050774)2.65206408
120regulation of female receptivity (GO:0045924)2.64128998
121regulation of clathrin-mediated endocytosis (GO:2000369)2.63735594
122positive regulation of synaptic transmission (GO:0050806)2.61682959
123negative regulation of microtubule polymerization (GO:0031115)2.59909676
124positive regulation of dendrite development (GO:1900006)2.58143259
125semaphorin-plexin signaling pathway (GO:0071526)2.55012324
126signal complex assembly (GO:0007172)2.53476715
127cortical actin cytoskeleton organization (GO:0030866)2.50827551
128vesicle docking involved in exocytosis (GO:0006904)2.50641863
129negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.50237593
130cellular response to catecholamine stimulus (GO:0071870)2.49322763
131cellular response to monoamine stimulus (GO:0071868)2.49322763
132response to acidic pH (GO:0010447)2.49013046
133axon extension (GO:0048675)2.45949778
134establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.44258932
135mitochondrion transport along microtubule (GO:0047497)2.44258932
136regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway 2.43003389
137positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling2.43003389
138regulation of synaptic transmission (GO:0050804)2.42569571

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.33539015
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.05733282
3* RARB_27405468_Chip-Seq_BRAIN_Mouse3.00766668
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.86114591
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.84331877
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.79171619
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.79171619
8SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.77617233
9DROSHA_22980978_ChIP-Seq_HELA_Human2.72358734
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.67778109
11MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.64126321
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.56251097
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.44661712
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.39103873
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.36012105
16SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.35762644
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.25908501
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.22060549
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16159859
20ELK3_25401928_ChIP-Seq_HUVEC_Human2.15312239
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.14649401
22REST_21632747_ChIP-Seq_MESCs_Mouse2.14324237
23EZH2_27294783_Chip-Seq_ESCs_Mouse2.14062322
24IKZF1_21737484_ChIP-ChIP_HCT116_Human2.10993456
25ZFP281_18757296_ChIP-ChIP_E14_Mouse2.08474299
26ERG_21242973_ChIP-ChIP_JURKAT_Human2.08217917
27TP63_17297297_ChIP-ChIP_HaCaT_Human2.04485981
28WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.00916707
29EED_16625203_ChIP-ChIP_MESCs_Mouse1.99993517
30KDM2B_26808549_Chip-Seq_K562_Human1.98978539
31VDR_21846776_ChIP-Seq_THP-1_Human1.96837900
32REST_18959480_ChIP-ChIP_MESCs_Mouse1.89050814
33TET1_21451524_ChIP-Seq_MESCs_Mouse1.84964774
34GBX2_23144817_ChIP-Seq_PC3_Human1.83125139
35SRY_22984422_ChIP-ChIP_TESTIS_Rat1.80080601
36TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.69738783
37EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.68528341
38KDM2B_26808549_Chip-Seq_SUP-B15_Human1.67011587
39CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.66535577
40DNAJC2_21179169_ChIP-ChIP_NT2_Human1.66238320
41P68_20966046_ChIP-Seq_HELA_Human1.65569136
42TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62207299
43* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.61325790
44* TCF7_22412390_ChIP-Seq_EML_Mouse1.60913012
45ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.60837531
46SA1_27219007_Chip-Seq_ERYTHROID_Human1.54951972
47MYC_22102868_ChIP-Seq_BL_Human1.53826692
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.53594469
49NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.53174256
50SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.50098286
51AR_21572438_ChIP-Seq_LNCaP_Human1.49694396
52WT1_25993318_ChIP-Seq_PODOCYTE_Human1.47125579
53SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.46667358
54RING1B_27294783_Chip-Seq_ESCs_Mouse1.45633879
55CTCF_27219007_Chip-Seq_ERYTHROID_Human1.45042750
56TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.43411224
57ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.41289755
58* LXR_22292898_ChIP-Seq_THP-1_Human1.35824596
59KDM2B_26808549_Chip-Seq_DND41_Human1.34818054
60RING1B_27294783_Chip-Seq_NPCs_Mouse1.33530694
61RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.33396305
62PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.31692649
63RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.31412964
64DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.31092011
65GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.29458246
66EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.27819868
67TRIM28_21343339_ChIP-Seq_HEK293_Human1.25808561
68ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.25301148
69KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.24445712
70KDM2B_26808549_Chip-Seq_JURKAT_Human1.22411371
71ELF1_20517297_ChIP-Seq_JURKAT_Human1.22311146
72THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.20706358
73RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.20327644
74ESR2_21235772_ChIP-Seq_MCF-7_Human1.20313838
75ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.19212036
76KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.18931162
77* SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.17604580
78SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.17383981
79CTCF_27219007_Chip-Seq_Bcells_Human1.14912638
80PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.14689352
81AR_19668381_ChIP-Seq_PC3_Human1.14582705
82CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.13664930
83NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.13346473
84TP53_22127205_ChIP-Seq_IMR90_Human1.12442943
85* TET1_21490601_ChIP-Seq_MESCs_Mouse1.12315932
86MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.12095302
87TP53_20018659_ChIP-ChIP_R1E_Mouse1.11023264
88CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.09887321
89ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05433437
90SOX2_21211035_ChIP-Seq_LN229_Gbm1.03196753
91TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.03168413
92NR3C1_23031785_ChIP-Seq_PC12_Mouse1.01778563
93SMC1_22415368_ChIP-Seq_MEFs_Mouse1.01586152
94SA1_27219007_Chip-Seq_Bcells_Human1.01389351
95SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01206728
96CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.01120216
97CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.01049178
98OCT4_19829295_ChIP-Seq_ESCs_Human1.00269636
99KLF4_19829295_ChIP-Seq_ESCs_Human0.99978114
100RARG_19884340_ChIP-ChIP_MEFs_Mouse0.99234710
101OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.98974916
102NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.98901140
103SMC4_20622854_ChIP-Seq_HELA_Human0.98577424
104ESR1_20079471_ChIP-ChIP_T-47D_Human0.98080618
105SMC3_22415368_ChIP-Seq_MEFs_Mouse0.97929534
106P300_27058665_Chip-Seq_ZR-75-30cells_Human0.97780446
107CREB1_26743006_Chip-Seq_LNCaP_Human0.97373752
108VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.97183779
109SMAD3_21741376_ChIP-Seq_HESCs_Human0.95442789
110RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.95288100
111GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.95128800
112BCOR_27268052_Chip-Seq_Bcells_Human0.94985141
113AHR_22903824_ChIP-Seq_MCF-7_Human0.94909674
114KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93947165
115SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.92193162
116EP300_21415370_ChIP-Seq_HL-1_Mouse0.91625560
117SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.90559717
118SMAD4_21741376_ChIP-Seq_HESCs_Human0.89685799
119TP53_23651856_ChIP-Seq_MEFs_Mouse0.88249830
120YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88206792
121RACK7_27058665_Chip-Seq_MCF-7_Human0.86398898
122SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86258147
123STAT6_21828071_ChIP-Seq_BEAS2B_Human0.86184220
124SMAD4_21799915_ChIP-Seq_A2780_Human0.85750541
125CTBP2_25329375_ChIP-Seq_LNCAP_Human0.84927696
126CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.84790217
127SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.84616345
128RXR_22108803_ChIP-Seq_LS180_Human0.84510980
129CDX2_19796622_ChIP-Seq_MESCs_Mouse0.84085239
130P53_22127205_ChIP-Seq_FIBROBLAST_Human0.84014300
131ZNF274_21170338_ChIP-Seq_K562_Hela0.83933912
132ARNT_22903824_ChIP-Seq_MCF-7_Human0.83405706
133UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.82843598

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.64436214
2MP0002822_catalepsy4.40121573
3MP0003635_abnormal_synaptic_transmissio3.81801683
4MP0003880_abnormal_central_pattern3.26218711
5MP0004270_analgesia3.25952342
6MP0002063_abnormal_learning/memory/cond3.03758241
7MP0009745_abnormal_behavioral_response2.94598064
8MP0002064_seizures2.70617922
9MP0009046_muscle_twitch2.56532816
10MP0004858_abnormal_nervous_system2.50074137
11MP0002572_abnormal_emotion/affect_behav2.28637864
12MP0001968_abnormal_touch/_nociception2.24341713
13MP0001486_abnormal_startle_reflex2.12394439
14MP0002734_abnormal_mechanical_nocicepti2.10488517
15MP0002272_abnormal_nervous_system2.07937699
16MP0005423_abnormal_somatic_nervous2.07695596
17MP0002909_abnormal_adrenal_gland2.06810673
18MP0009780_abnormal_chondrocyte_physiolo2.06780684
19MP0005623_abnormal_meninges_morphology2.02968658
20MP0005058_abnormal_lysosome_morphology2.00760540
21MP0003283_abnormal_digestive_organ1.88802561
22MP0004510_myositis1.86640280
23MP0008569_lethality_at_weaning1.83125494
24MP0004811_abnormal_neuron_physiology1.81474880
25MP0001849_ear_inflammation1.80426445
26MP0000751_myopathy1.79293828
27MP0000013_abnormal_adipose_tissue1.78542305
28MP0003329_amyloid_beta_deposits1.78241599
29MP0002733_abnormal_thermal_nociception1.74568543
30MP0003705_abnormal_hypodermis_morpholog1.73989220
31MP0001501_abnormal_sleep_pattern1.69683897
32MP0001970_abnormal_pain_threshold1.64029925
33MP0003172_abnormal_lysosome_physiology1.61178657
34MP0002736_abnormal_nociception_after1.58175224
35MP0002249_abnormal_larynx_morphology1.55860855
36MP0008260_abnormal_autophagy1.52201406
37MP0001346_abnormal_lacrimal_gland1.51649479
38MP0004885_abnormal_endolymph1.51140026
39MP0000955_abnormal_spinal_cord1.47308786
40MP0002184_abnormal_innervation1.46849478
41MP0000778_abnormal_nervous_system1.45738909
42MP0005386_behavior/neurological_phenoty1.42401993
43MP0004924_abnormal_behavior1.42401993
44MP0001440_abnormal_grooming_behavior1.42260688
45MP0003303_peritoneal_inflammation1.41338032
46MP0003123_paternal_imprinting1.39362730
47MP0002735_abnormal_chemical_nociception1.38998197
48MP0002067_abnormal_sensory_capabilities1.38278100
49MP0008961_abnormal_basal_metabolism1.35228987
50MP0002557_abnormal_social/conspecific_i1.34694059
51MP0008438_abnormal_cutaneous_collagen1.33777251
52MP0003633_abnormal_nervous_system1.29589756
53MP0010030_abnormal_orbit_morphology1.28015952
54MP0003075_altered_response_to1.27568069
55MP0003879_abnormal_hair_cell1.27041498
56MP0002066_abnormal_motor_capabilities/c1.25224879
57MP0005167_abnormal_blood-brain_barrier1.24690533
58MP0002882_abnormal_neuron_morphology1.21624545
59MP0000569_abnormal_digit_pigmentation1.21567483
60MP0001177_atelectasis1.15248067
61MP0003122_maternal_imprinting1.12992986
62MP0003566_abnormal_cell_adhesion1.09520511
63MP0001984_abnormal_olfaction1.09512014
64MP0004233_abnormal_muscle_weight1.07635757
65MP0005257_abnormal_intraocular_pressure1.06091630
66MP0002152_abnormal_brain_morphology1.05476536
67MP0005409_darkened_coat_color1.04957858
68MP0003631_nervous_system_phenotype1.03216678
69MP0000003_abnormal_adipose_tissue1.01691815
70MP0008874_decreased_physiological_sensi1.00467756
71MP0000678_abnormal_parathyroid_gland0.99357203
72MP0010234_abnormal_vibrissa_follicle0.98583666
73MP0001299_abnormal_eye_distance/0.94721994
74MP0003300_gastrointestinal_ulcer0.94431751
75MP0003634_abnormal_glial_cell0.93900139
76MP0004085_abnormal_heartbeat0.93772648
77MP0000534_abnormal_ureter_morphology0.92689785
78MP0001348_abnormal_lacrimal_gland0.90701309
79MP0009278_abnormal_bone_marrow0.89911186
80MP0001529_abnormal_vocalization0.89237808
81MP0004272_abnormal_basement_membrane0.88437119
82MP0000733_abnormal_muscle_development0.88316848
83MP0005646_abnormal_pituitary_gland0.88135511
84MP0003436_decreased_susceptibility_to0.87910474
85MP0002089_abnormal_postnatal_growth/wei0.86631425
86MP0004145_abnormal_muscle_electrophysio0.86067408
87MP0004130_abnormal_muscle_cell0.85603803
88MP0000681_abnormal_thyroid_gland0.85370469
89MP0001958_emphysema0.84257725
90MP0003690_abnormal_glial_cell0.83171774
91MP0005166_decreased_susceptibility_to0.83109849
92MP0003787_abnormal_imprinting0.83027643
93MP0005451_abnormal_body_composition0.81521874
94MP0000537_abnormal_urethra_morphology0.81464885
95MP0003045_fibrosis0.81380610
96MP0003137_abnormal_impulse_conducting0.81288590
97MP0002069_abnormal_eating/drinking_beha0.80439065
98MP0000920_abnormal_myelination0.80234408
99MP0001905_abnormal_dopamine_level0.79530570
100MP0003091_abnormal_cell_migration0.78627408
101MP0005275_abnormal_skin_tensile0.77161700
102MP0000747_muscle_weakness0.76739569
103MP0001502_abnormal_circadian_rhythm0.74705495
104MP0005076_abnormal_cell_differentiation0.74415325
105MP0008872_abnormal_physiological_respon0.72130831
106MP0003279_aneurysm0.71889223
107MP0002837_dystrophic_cardiac_calcinosis0.71188064
108MP0003385_abnormal_body_wall0.70991581
109MP0002653_abnormal_ependyma_morphology0.70649106
110MP0004087_abnormal_muscle_fiber0.70323442
111MP0003632_abnormal_nervous_system0.69786366
112MP0005499_abnormal_olfactory_system0.69304413
113MP0005394_taste/olfaction_phenotype0.69304413
114MP0002090_abnormal_vision0.69288691
115MP0000604_amyloidosis0.66559607
116MP0003453_abnormal_keratinocyte_physiol0.66488362
117MP0005508_abnormal_skeleton_morphology0.66179175
118MP0001963_abnormal_hearing_physiology0.66124225
119MP0004215_abnormal_myocardial_fiber0.65355599
120MP0004947_skin_inflammation0.64303994
121MP0003861_abnormal_nervous_system0.63927600
122MP0000767_abnormal_smooth_muscle0.61541778
123MP0005620_abnormal_muscle_contractility0.60580049
124MP0002234_abnormal_pharynx_morphology0.60365624
125MP0000049_abnormal_middle_ear0.59967314
126MP0005503_abnormal_tendon_morphology0.59850846
127MP0000759_abnormal_skeletal_muscle0.59834240
128MP0001943_abnormal_respiration0.58970294
129MP0002108_abnormal_muscle_morphology0.58589361
130MP0009053_abnormal_anal_canal0.58322506
131MP0005375_adipose_tissue_phenotype0.58280878
132MP0004185_abnormal_adipocyte_glucose0.58083601
133MP0002998_abnormal_bone_remodeling0.56036306
134MP0005595_abnormal_vascular_smooth0.55651933

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)6.35361860
2Focal motor seizures (HP:0011153)4.83688031
3Focal seizures (HP:0007359)4.19661301
4Visual hallucinations (HP:0002367)3.67025180
5Action tremor (HP:0002345)3.53647491
6Annular pancreas (HP:0001734)3.13478841
7Ankle clonus (HP:0011448)3.08688611
8Abnormality of the lower motor neuron (HP:0002366)3.04983167
9Torticollis (HP:0000473)2.96845938
10Supranuclear gaze palsy (HP:0000605)2.90833820
11Neuronal loss in central nervous system (HP:0002529)2.88296566
12Abnormality of binocular vision (HP:0011514)2.84838234
13Diplopia (HP:0000651)2.84838234
14Upper limb amyotrophy (HP:0009129)2.81039094
15Distal upper limb amyotrophy (HP:0007149)2.81039094
16Poor eye contact (HP:0000817)2.80870410
17Apathy (HP:0000741)2.79827833
18Pointed chin (HP:0000307)2.76753287
19Atonic seizures (HP:0010819)2.74531013
20Depression (HP:0000716)2.73903281
21Epileptic encephalopathy (HP:0200134)2.71300501
22Protrusio acetabuli (HP:0003179)2.71152831
23Abnormal social behavior (HP:0012433)2.70633839
24Impaired social interactions (HP:0000735)2.70633839
25Impaired vibration sensation in the lower limbs (HP:0002166)2.68782798
26Resting tremor (HP:0002322)2.68763327
27Progressive cerebellar ataxia (HP:0002073)2.62899296
28Lower limb amyotrophy (HP:0007210)2.62464469
29Insomnia (HP:0100785)2.60419172
30Diminished motivation (HP:0000745)2.58731533
31Shallow orbits (HP:0000586)2.57925267
32Dysdiadochokinesis (HP:0002075)2.56868786
33Focal dystonia (HP:0004373)2.53555634
34Absence seizures (HP:0002121)2.53455579
35Urinary bladder sphincter dysfunction (HP:0002839)2.51703509
36Urinary urgency (HP:0000012)2.50487345
37Megalencephaly (HP:0001355)2.46295172
38Dysmetric saccades (HP:0000641)2.46000873
39Ankyloglossia (HP:0010296)2.45267806
40Generalized tonic-clonic seizures (HP:0002069)2.45158070
41Hemiplegia (HP:0002301)2.41845506
42Cerebral aneurysm (HP:0004944)2.39298846
43Craniofacial dystonia (HP:0012179)2.38882359
44Papilledema (HP:0001085)2.36275201
45Broad distal phalanx of finger (HP:0009836)2.35094439
46Hyperacusis (HP:0010780)2.34010316
47Anxiety (HP:0000739)2.31790684
48Abnormal eating behavior (HP:0100738)2.31684880
49Increased variability in muscle fiber diameter (HP:0003557)2.28095214
50Termporal pattern (HP:0011008)2.27438683
51Insidious onset (HP:0003587)2.27438683
52Genetic anticipation (HP:0003743)2.27172829
53Dysmetria (HP:0001310)2.26197003
54Peripheral hypomyelination (HP:0007182)2.24297456
55Febrile seizures (HP:0002373)2.24185283
56Dialeptic seizures (HP:0011146)2.22032997
57Postural instability (HP:0002172)2.21854829
58Bundle branch block (HP:0011710)2.21485708
59Ulnar bowing (HP:0003031)2.21069613
60Cerebral inclusion bodies (HP:0100314)2.16493656
61Ventricular fibrillation (HP:0001663)2.15787547
62Premature rupture of membranes (HP:0001788)2.15499558
63Achilles tendon contracture (HP:0001771)2.14884198
64Mitral regurgitation (HP:0001653)2.14767230
65Broad-based gait (HP:0002136)2.14107461
66Neoplasm of the heart (HP:0100544)2.12694010
67Amblyopia (HP:0000646)2.12265015
68Vertebral compression fractures (HP:0002953)2.11772204
69Truncal ataxia (HP:0002078)2.10267703
70Bladder diverticulum (HP:0000015)2.09013604
71Intention tremor (HP:0002080)2.08682941
72Gaze-evoked nystagmus (HP:0000640)2.07074748
73Stereotypic behavior (HP:0000733)2.05377073
74Bowel diverticulosis (HP:0005222)2.04244585
75Broad metatarsal (HP:0001783)2.03019301
76Long palpebral fissure (HP:0000637)2.03002782
77Obstructive sleep apnea (HP:0002870)2.02439585
78Tetraplegia (HP:0002445)2.01980708
79Hypercortisolism (HP:0001578)2.01934271
80Distal lower limb amyotrophy (HP:0008944)2.00663396
81Abnormality of oral frenula (HP:0000190)1.98724797
82Hypoventilation (HP:0002791)1.96564008
83Increased cerebral lipofuscin (HP:0011813)1.94720971
84Lower limb muscle weakness (HP:0007340)1.94661249
85Rapidly progressive (HP:0003678)1.94582365
86Impaired smooth pursuit (HP:0007772)1.94324811
87Stridor (HP:0010307)1.93619647
88Bronchomalacia (HP:0002780)1.93186303
89Disproportionate tall stature (HP:0001519)1.93160986
90Spastic gait (HP:0002064)1.93020927
91Dilatation of the ascending aorta (HP:0005111)1.92264827
92Turricephaly (HP:0000262)1.91845911
93Hemiparesis (HP:0001269)1.91361218
94Elfin facies (HP:0004428)1.90874466
95Genu recurvatum (HP:0002816)1.90308968
96Arnold-Chiari malformation (HP:0002308)1.89338166
97Hammertoe (HP:0001765)1.89140795
98Lower limb asymmetry (HP:0100559)1.88780902
99Delusions (HP:0000746)1.88512849
100Nuclear cataract (HP:0100018)1.88077230
101Abnormality of the Achilles tendon (HP:0005109)1.87642716
102Hand muscle atrophy (HP:0009130)1.87393921
103Neurofibrillary tangles (HP:0002185)1.86733014
104Polygenic inheritance (HP:0010982)1.86518186
105Buphthalmos (HP:0000557)1.85395166
106Broad face (HP:0000283)1.85368228
107Spinal canal stenosis (HP:0003416)1.85299290
108Vascular tortuosity (HP:0004948)1.83017995
109Aplasia involving bones of the extremities (HP:0009825)1.82837990
110Aplasia involving bones of the upper limbs (HP:0009823)1.82837990
111Aplasia of the phalanges of the hand (HP:0009802)1.82837990
112Abnormality of skeletal muscle fiber size (HP:0012084)1.82816009
113Mutism (HP:0002300)1.82510293
114Difficulty running (HP:0009046)1.81631730
115Fragile skin (HP:0001030)1.81600392
116Arterial tortuosity (HP:0005116)1.81333457
117Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.80541459
118Ankle contracture (HP:0006466)1.80351883
119Scanning speech (HP:0002168)1.79863405
120Dementia (HP:0000726)1.79212676
121Bradykinesia (HP:0002067)1.78928985
122Axonal loss (HP:0003447)1.78193494
123Prolonged QT interval (HP:0001657)1.76139827
124Macroorchidism (HP:0000053)1.75988897
125Hyperparathyroidism (HP:0000843)1.75681085
126Thin bony cortex (HP:0002753)1.75247912
127Truncus arteriosus (HP:0001660)1.74825193
128Overgrowth (HP:0001548)1.74078821
129Renal duplication (HP:0000075)1.73473529
130Distal sensory impairment (HP:0002936)1.73388988
131Overriding aorta (HP:0002623)1.72095284
132Mitral valve prolapse (HP:0001634)1.69150057
133Dysostosis multiplex (HP:0000943)1.66629437
134Slow saccadic eye movements (HP:0000514)1.66281250

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.52976067
2MAP3K93.41688130
3NTRK33.29578226
4PRKD33.05842906
5SMG12.81824357
6TRIB32.58289712
7DAPK22.53007870
8KSR22.52994525
9PAK62.49636971
10MINK12.30529557
11CAMKK12.30056329
12NTRK12.14704229
13MARK12.12087160
14MAP3K112.02202849
15TYRO31.88847485
16MAP3K41.84196751
17RIPK11.82391205
18NTRK21.80528420
19LATS21.74229255
20TAOK11.68193820
21DDR21.60499387
22TESK11.59790448
23IRAK31.49855874
24STK381.47924615
25TAOK21.47738233
26SIK21.47462815
27KSR11.45769253
28CDK51.45025994
29PDGFRA1.42478282
30PKN21.40330760
31LMTK21.39171450
32MAP3K21.29293694
33SIK11.28408247
34ERN11.24508096
35DAPK11.24112509
36MAP2K41.23543859
37RET1.21989875
38PRKCH1.16624210
39NEK11.13642811
40ALK1.13631697
41BMX1.13038369
42RIPK41.10756523
43ICK1.09479099
44PHKG11.08242959
45PHKG21.08242959
46UHMK11.07120957
47PRPF4B1.07060724
48NME21.05487597
49ARAF0.98381310
50PTK2B0.98034959
51CDK150.97121470
52PAK30.95828056
53CAMKK20.95156072
54BRAF0.95012309
55FES0.94816241
56CDK180.94637557
57CDK140.93232949
58STK110.91965563
59MARK20.90318956
60DMPK0.89120389
61GRK50.88635006
62MAP2K70.88366104
63CDK11A0.84453109
64IRAK20.83959245
65TESK20.83440550
66CAMK1D0.82679827
67SCYL20.82311344
68MAPK120.80779685
69PRKCG0.77961989
70FGFR40.76703188
71PLK20.75859212
72MAP3K130.74138809
73MAP2K30.74131113
74RAF10.73877499
75CDC42BPA0.71316424
76PDPK10.70526210
77TTN0.69833788
78WNK10.69822760
79CAMK10.68345651
80PTK20.68046104
81SGK2230.65900704
82SGK4940.65900704
83EPHB10.64441254
84MAP2K10.64431674
85DAPK30.64417562
86SGK30.63561092
87FER0.62290245
88CAMK1G0.61248503
89PDK10.61074750
90PRKD20.60006772
91CAMK2A0.59591669
92MAP3K10.58630078
93PRKG20.56043690
94MAP3K70.55865828
95BRSK10.55665803
96CAMK2G0.55449436
97SGK10.55429139
98PINK10.55121944
99CDK120.54481175
100ROCK20.53715134
101CAMK40.50242329
102ROCK10.49666837
103TNK20.49469329
104CDK190.49441889
105RPS6KA30.48622126
106LIMK10.48438485
107FYN0.48003331
108EEF2K0.47991533
109MAPK130.47916820
110CAMK2B0.46879778
111PRKCZ0.45310615
112MAP3K100.44779325
113ABL20.44577277
114MAPK100.44190059
115PDGFRB0.44119040
116TGFBR20.43320700
117PRKD10.43241045
118MOS0.42954637
119EPHB20.42234295
120RPS6KC10.42203803
121RPS6KL10.42203803
122MTOR0.41950664
123FGFR10.41816883
124RPS6KA20.41763950
125FGFR20.41315084
126PAK40.41232990
127MAP3K120.38900051
128PAK20.37930642
129PTK60.37685486

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047402.74832289
2Synaptic vesicle cycle_Homo sapiens_hsa047212.64633447
3Circadian entrainment_Homo sapiens_hsa047132.28202730
4Nicotine addiction_Homo sapiens_hsa050332.24816220
5Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.19125763
6GABAergic synapse_Homo sapiens_hsa047272.18961283
7Long-term potentiation_Homo sapiens_hsa047202.18807354
8Glutamatergic synapse_Homo sapiens_hsa047242.10430735
9Morphine addiction_Homo sapiens_hsa050322.06563068
10Amphetamine addiction_Homo sapiens_hsa050312.04291803
11Dopaminergic synapse_Homo sapiens_hsa047281.95754188
12Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.92717483
13Cholinergic synapse_Homo sapiens_hsa047251.81541963
14Salivary secretion_Homo sapiens_hsa049701.81463624
15Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.78420461
16Gastric acid secretion_Homo sapiens_hsa049711.77562057
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.74415067
18Cocaine addiction_Homo sapiens_hsa050301.73815911
19Nitrogen metabolism_Homo sapiens_hsa009101.64170867
20Insulin secretion_Homo sapiens_hsa049111.60121572
21Oxytocin signaling pathway_Homo sapiens_hsa049211.59373016
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.54338663
23Renin secretion_Homo sapiens_hsa049241.51539911
24Vitamin B6 metabolism_Homo sapiens_hsa007501.51353252
25Gap junction_Homo sapiens_hsa045401.51048157
26GnRH signaling pathway_Homo sapiens_hsa049121.47524612
27Glioma_Homo sapiens_hsa052141.45590997
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.37606258
29Long-term depression_Homo sapiens_hsa047301.33531801
30Estrogen signaling pathway_Homo sapiens_hsa049151.29356710
31Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.28928330
32Calcium signaling pathway_Homo sapiens_hsa040201.27153657
33Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.23079539
34cAMP signaling pathway_Homo sapiens_hsa040241.20510154
35Notch signaling pathway_Homo sapiens_hsa043301.18749485
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17617559
37Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.15988668
38Dilated cardiomyopathy_Homo sapiens_hsa054141.15835030
39Axon guidance_Homo sapiens_hsa043601.14766204
40Melanogenesis_Homo sapiens_hsa049161.11974762
41Taste transduction_Homo sapiens_hsa047421.09299049
42Serotonergic synapse_Homo sapiens_hsa047261.09240030
43ErbB signaling pathway_Homo sapiens_hsa040121.08605251
44Type II diabetes mellitus_Homo sapiens_hsa049301.07072185
45Phospholipase D signaling pathway_Homo sapiens_hsa040721.04806835
46Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.04780271
47cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03433788
48Dorso-ventral axis formation_Homo sapiens_hsa043200.99757738
49Other glycan degradation_Homo sapiens_hsa005110.99226423
50Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.97956044
51VEGF signaling pathway_Homo sapiens_hsa043700.97908735
52Phosphatidylinositol signaling system_Homo sapiens_hsa040700.95362981
53mTOR signaling pathway_Homo sapiens_hsa041500.94574247
54Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.93574359
55Neurotrophin signaling pathway_Homo sapiens_hsa047220.93374948
56Sulfur relay system_Homo sapiens_hsa041220.93055005
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.91715688
58Rap1 signaling pathway_Homo sapiens_hsa040150.90028337
59Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.89697770
60Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.88709568
61Oocyte meiosis_Homo sapiens_hsa041140.85236229
62Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.84255776
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.83133612
64Non-small cell lung cancer_Homo sapiens_hsa052230.82686353
65Salmonella infection_Homo sapiens_hsa051320.81989819
66Endometrial cancer_Homo sapiens_hsa052130.81589901
67Glycosaminoglycan degradation_Homo sapiens_hsa005310.81519977
68Thyroid hormone synthesis_Homo sapiens_hsa049180.78604453
69Inositol phosphate metabolism_Homo sapiens_hsa005620.77018128
70Osteoclast differentiation_Homo sapiens_hsa043800.76586378
71B cell receptor signaling pathway_Homo sapiens_hsa046620.75412777
72Acute myeloid leukemia_Homo sapiens_hsa052210.74581465
73Choline metabolism in cancer_Homo sapiens_hsa052310.74516060
74Pancreatic cancer_Homo sapiens_hsa052120.74303119
75Longevity regulating pathway - mammal_Homo sapiens_hsa042110.73719790
76Endocytosis_Homo sapiens_hsa041440.73711307
77MAPK signaling pathway_Homo sapiens_hsa040100.73532553
78Focal adhesion_Homo sapiens_hsa045100.73331973
79Lysosome_Homo sapiens_hsa041420.70559832
80Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69801857
81Renal cell carcinoma_Homo sapiens_hsa052110.69459813
82Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.69383683
83Cardiac muscle contraction_Homo sapiens_hsa042600.68826370
84Toll-like receptor signaling pathway_Homo sapiens_hsa046200.68731058
85Proteoglycans in cancer_Homo sapiens_hsa052050.67644632
86Collecting duct acid secretion_Homo sapiens_hsa049660.66512879
87Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66462854
88Shigellosis_Homo sapiens_hsa051310.65363938
89Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.63198788
90Insulin signaling pathway_Homo sapiens_hsa049100.63165153
91Ras signaling pathway_Homo sapiens_hsa040140.62501016
92Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.62231394
93Sphingolipid signaling pathway_Homo sapiens_hsa040710.61391008
94Central carbon metabolism in cancer_Homo sapiens_hsa052300.61366617
95Glucagon signaling pathway_Homo sapiens_hsa049220.61365809
96Leukocyte transendothelial migration_Homo sapiens_hsa046700.61264513
97Tight junction_Homo sapiens_hsa045300.60487601
98Pancreatic secretion_Homo sapiens_hsa049720.60319242
99Bile secretion_Homo sapiens_hsa049760.60164992
100Hippo signaling pathway_Homo sapiens_hsa043900.59041649
101Prolactin signaling pathway_Homo sapiens_hsa049170.57913152
102Bladder cancer_Homo sapiens_hsa052190.57715456
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.57608302
104Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55226623
105Vibrio cholerae infection_Homo sapiens_hsa051100.55134050
106Chronic myeloid leukemia_Homo sapiens_hsa052200.53991712
107Amoebiasis_Homo sapiens_hsa051460.51919971
108Wnt signaling pathway_Homo sapiens_hsa043100.51413373
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.50976744
110AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.50472664
111Colorectal cancer_Homo sapiens_hsa052100.50003124
112Platelet activation_Homo sapiens_hsa046110.49889369
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.49817349
114Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.48130068
115Tuberculosis_Homo sapiens_hsa051520.47802103
116TNF signaling pathway_Homo sapiens_hsa046680.47676129
117Alcoholism_Homo sapiens_hsa050340.47636041
118HIF-1 signaling pathway_Homo sapiens_hsa040660.47151437
119Hedgehog signaling pathway_Homo sapiens_hsa043400.46491592
120Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.46428565
121ECM-receptor interaction_Homo sapiens_hsa045120.45625878
122Prion diseases_Homo sapiens_hsa050200.43418451
123Chemokine signaling pathway_Homo sapiens_hsa040620.43017109

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