KCTD20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)4.88784915
2Golgi transport vesicle coating (GO:0048200)4.52201442
3COPI coating of Golgi vesicle (GO:0048205)4.52201442
4protein localization to kinetochore (GO:0034501)4.46983038
5negative regulation of erythrocyte differentiation (GO:0045647)4.17122654
6mitotic nuclear envelope disassembly (GO:0007077)4.06076693
7nuclear envelope disassembly (GO:0051081)3.96648893
8membrane disassembly (GO:0030397)3.96648893
9mitotic chromosome condensation (GO:0007076)3.84365004
10negative regulation of phagocytosis (GO:0050765)3.82157579
11regulation of translational termination (GO:0006449)3.79956813
12folic acid-containing compound biosynthetic process (GO:0009396)3.78300422
13nuclear pore organization (GO:0006999)3.73289348
14negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.71677721
15protein localization to chromosome, centromeric region (GO:0071459)3.68675217
16protein localization to endosome (GO:0036010)3.64670961
17nuclear pore complex assembly (GO:0051292)3.64118035
18regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.55719754
19sister chromatid segregation (GO:0000819)3.55277878
20pentose-phosphate shunt (GO:0006098)3.53550108
21IMP biosynthetic process (GO:0006188)3.48261245
22platelet aggregation (GO:0070527)3.46492495
23stress fiber assembly (GO:0043149)3.46049501
24negative regulation of RNA splicing (GO:0033119)3.45784571
25DNA topological change (GO:0006265)3.44650474
26positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.44577898
27regulation of spindle organization (GO:0090224)3.44248980
28cell adhesion mediated by integrin (GO:0033627)3.34641590
29glucocorticoid receptor signaling pathway (GO:0042921)3.32101695
30nuclear envelope organization (GO:0006998)3.31794592
31mitotic sister chromatid segregation (GO:0000070)3.28740106
32regulation of early endosome to late endosome transport (GO:2000641)3.28601939
33hypotonic response (GO:0006971)3.27961241
34Arp2/3 complex-mediated actin nucleation (GO:0034314)3.26972748
35negative regulation of protein localization to plasma membrane (GO:1903077)3.26442815
36regulation of translational fidelity (GO:0006450)3.22925228
37DNA duplex unwinding (GO:0032508)3.20864322
38DNA replication-dependent nucleosome assembly (GO:0006335)3.20197276
39DNA replication-dependent nucleosome organization (GO:0034723)3.20197276
403-UTR-mediated mRNA stabilization (GO:0070935)3.19244474
41IMP metabolic process (GO:0046040)3.18741097
42pinocytosis (GO:0006907)3.18372186
43dosage compensation (GO:0007549)3.18170429
44DNA geometric change (GO:0032392)3.17259727
45extracellular fibril organization (GO:0043206)3.16429768
46megakaryocyte development (GO:0035855)3.16358427
47skin morphogenesis (GO:0043589)3.16096228
48regulation of integrin activation (GO:0033623)3.15613919
49DNA strand elongation involved in DNA replication (GO:0006271)3.12714426
50positive regulation of macrophage differentiation (GO:0045651)3.12282213
51regulation of mitotic spindle organization (GO:0060236)3.12227229
52NADPH regeneration (GO:0006740)3.12160653
53fibril organization (GO:0097435)3.10540997
54peptidyl-lysine dimethylation (GO:0018027)3.08131115
55histone H2A monoubiquitination (GO:0035518)3.03216690
56translesion synthesis (GO:0019985)3.02096279
57positive regulation of receptor recycling (GO:0001921)3.01209230
58platelet degranulation (GO:0002576)3.00226170
59negative regulation of histone methylation (GO:0031061)2.96990916
60regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.94547290
61regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.91817489
62DNA strand elongation (GO:0022616)2.91448707
63mRNA stabilization (GO:0048255)2.90379912
64RNA stabilization (GO:0043489)2.90379912
65DNA replication initiation (GO:0006270)2.89854438
66negative regulation of mRNA processing (GO:0050686)2.86772616
67pre-miRNA processing (GO:0031054)2.84678255
68vesicle coating (GO:0006901)2.83982644
69mitotic sister chromatid cohesion (GO:0007064)2.83505430
70iron ion import (GO:0097286)2.83058817
71spliceosomal tri-snRNP complex assembly (GO:0000244)2.82723245
72negative regulation of anoikis (GO:2000811)2.82434064
73definitive hemopoiesis (GO:0060216)2.82291818
74protoporphyrinogen IX metabolic process (GO:0046501)2.81638302
75nucleobase biosynthetic process (GO:0046112)2.80979073
76histone-serine phosphorylation (GO:0035404)2.80270641
77positive regulation of chromosome segregation (GO:0051984)2.78622920
78neutrophil activation involved in immune response (GO:0002283)2.78422922
79collagen fibril organization (GO:0030199)2.78132239
80regulation of platelet aggregation (GO:0090330)2.77764326
81defense response to fungus (GO:0050832)2.77233631
82COPII vesicle coating (GO:0048208)2.76538746
83positive regulation of lamellipodium assembly (GO:0010592)2.76163807
84attachment of spindle microtubules to kinetochore (GO:0008608)2.75981045
85regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.75591272
86mitotic metaphase plate congression (GO:0007080)2.74573221
87angiogenesis involved in wound healing (GO:0060055)2.73450735
88negative regulation of cell size (GO:0045792)2.73084336
89peptidyl-arginine omega-N-methylation (GO:0035247)2.72748357
90regulation of DNA damage checkpoint (GO:2000001)2.71206855
91postreplication repair (GO:0006301)2.70904808
92corticosteroid receptor signaling pathway (GO:0031958)2.70218028
93basement membrane organization (GO:0071711)2.69487340
94thrombin receptor signaling pathway (GO:0070493)2.69439074
95positive regulation of gamma-delta T cell activation (GO:0046645)2.69373814
96positive regulation of endothelial cell apoptotic process (GO:2000353)2.69065958
97protein localization to chromosome (GO:0034502)2.68928758
98positive regulation of nuclease activity (GO:0032075)2.68504389
99regulation of RNA export from nucleus (GO:0046831)2.67740898
100pore complex assembly (GO:0046931)2.67632168
101embryonic process involved in female pregnancy (GO:0060136)2.67252248
102cortical actin cytoskeleton organization (GO:0030866)2.65435280
103cellular response to thyroid hormone stimulus (GO:0097067)2.65184561
104mitotic G1 DNA damage checkpoint (GO:0031571)2.64984654
105establishment of chromosome localization (GO:0051303)2.64556481
106platelet formation (GO:0030220)2.64031578
107negative regulation of mRNA metabolic process (GO:1903312)2.63987562
108response to muramyl dipeptide (GO:0032495)2.63276046
109mesodermal cell differentiation (GO:0048333)2.63259632
110DNA conformation change (GO:0071103)2.63075264
111regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.62744939
112alternative mRNA splicing, via spliceosome (GO:0000380)2.62018578
113positive regulation of blood coagulation (GO:0030194)2.61696539
114positive regulation of hemostasis (GO:1900048)2.61696539
115regulation of chromosome segregation (GO:0051983)2.61589248
116regulation of integrin-mediated signaling pathway (GO:2001044)2.61496276
117cytokinetic process (GO:0032506)2.60667671
118barbed-end actin filament capping (GO:0051016)2.60124917
119negative regulation of histone acetylation (GO:0035067)2.59257266
120maternal placenta development (GO:0001893)2.59125657
121positive regulation of blood vessel endothelial cell migration (GO:0043536)2.58923303
122regulation of sister chromatid cohesion (GO:0007063)2.58777191
123activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.58730418
124regulation of histone H3-K27 methylation (GO:0061085)2.57945422
125regulation of protein heterodimerization activity (GO:0043497)2.57661137
126formation of translation preinitiation complex (GO:0001731)2.57066816
127response to laminar fluid shear stress (GO:0034616)2.56966869
128telomere maintenance via semi-conservative replication (GO:0032201)2.54995067
129hepatocyte apoptotic process (GO:0097284)2.54904775
130retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.53704111
131peptidyl-arginine N-methylation (GO:0035246)2.52021784
132peptidyl-arginine methylation (GO:0018216)2.52021784
133low-density lipoprotein particle clearance (GO:0034383)2.51708870
134antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.51662489
135antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.51662489
136hemoglobin metabolic process (GO:0020027)2.50067181
137negative regulation of homotypic cell-cell adhesion (GO:0034111)2.50006656
138positive regulation of lamellipodium organization (GO:1902745)2.49717323
139positive regulation of cellular amide metabolic process (GO:0034250)2.49304268
140positive regulation of coagulation (GO:0050820)2.48963048
141chromatin assembly (GO:0031497)2.48650079
142heterochromatin organization (GO:0070828)2.48398543
143spindle assembly checkpoint (GO:0071173)2.48033641
144regulation of macrophage cytokine production (GO:0010935)2.47952511
145cell-substrate junction assembly (GO:0007044)2.47769724
146mitotic spindle assembly checkpoint (GO:0007094)2.47687856
147response to thyroid hormone (GO:0097066)2.47594409
148chromatin assembly or disassembly (GO:0006333)2.46358047
149chromosome condensation (GO:0030261)2.46056979
150regulation of nuclease activity (GO:0032069)2.44943582
151negative regulation of chromosome segregation (GO:0051985)2.44794267
152membrane protein ectodomain proteolysis (GO:0006509)2.43165042
153regulation of nucleobase-containing compound transport (GO:0032239)2.42773594
154response to peptidoglycan (GO:0032494)2.42331667
155mitotic recombination (GO:0006312)2.41193011
156protein-DNA complex disassembly (GO:0032986)2.40700447
157nucleosome disassembly (GO:0006337)2.40700447
158metaphase plate congression (GO:0051310)2.40299256
159regulation of platelet activation (GO:0010543)2.39563028
160negative regulation of mitotic sister chromatid segregation (GO:0033048)2.39351220
161membrane raft organization (GO:0031579)2.38273049
162platelet activation (GO:0030168)2.37306933
163regulation of anoikis (GO:2000209)2.37039215
164positive regulation of extracellular matrix organization (GO:1903055)2.35805724
165germinal center formation (GO:0002467)2.34558153
166negative regulation of establishment of protein localization to plasma membrane (GO:0090005)2.33070762
167homotypic cell-cell adhesion (GO:0034109)2.32702089
168negative regulation of fatty acid transport (GO:2000192)2.32432945
169detection of molecule of bacterial origin (GO:0032490)2.32088030
170positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.31424579
171fibroblast migration (GO:0010761)2.31135596
172lipopolysaccharide-mediated signaling pathway (GO:0031663)2.29227678
173cellular extravasation (GO:0045123)2.28116808
174cortical cytoskeleton organization (GO:0030865)2.26479464
175positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.23244820
176regulation of erythrocyte differentiation (GO:0045646)2.22759065
177pathway-restricted SMAD protein phosphorylation (GO:0060389)2.20944505
178wound healing, spreading of epidermal cells (GO:0035313)2.20148717
179integrin-mediated signaling pathway (GO:0007229)2.19867469
180myeloid cell development (GO:0061515)2.16400922
181SMAD protein complex assembly (GO:0007183)2.16064545
182adherens junction assembly (GO:0034333)2.14711591
183positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.13900710
184alpha-linolenic acid metabolic process (GO:0036109)2.13707380
185adenosine receptor signaling pathway (GO:0001973)2.13411397
186interleukin-6-mediated signaling pathway (GO:0070102)2.13392492
187retina vasculature morphogenesis in camera-type eye (GO:0061299)2.12283032
188sprouting angiogenesis (GO:0002040)2.11690521
189endoplasmic reticulum unfolded protein response (GO:0030968)2.09516747

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.43455978
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.01158740
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.00455467
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.76713636
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.42380402
6MYC_22102868_ChIP-Seq_BL_Human3.28031543
7E2F4_17652178_ChIP-ChIP_JURKAT_Human2.81126340
8NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.79124116
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.54973331
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.49853545
11WT1_19549856_ChIP-ChIP_CCG9911_Human2.42891484
12VDR_21846776_ChIP-Seq_THP-1_Human2.42570824
13SMAD_19615063_ChIP-ChIP_OVARY_Human2.31639310
14SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.30342982
15Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.25546072
16GATA1_19941826_ChIP-Seq_K562_Human2.18921279
17CIITA_25753668_ChIP-Seq_RAJI_Human2.02220391
18CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse2.00632522
19STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.96878475
20MYC_19079543_ChIP-ChIP_MESCs_Mouse1.95223426
21GATA2_21666600_ChIP-Seq_HMVEC_Human1.94381243
22ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.90612486
23RARG_19884340_ChIP-ChIP_MEFs_Mouse1.87026562
24MYB_21317192_ChIP-Seq_ERMYB_Mouse1.84024375
25RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.83562120
26NELFA_20434984_ChIP-Seq_ESCs_Mouse1.79858504
27SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.75905156
28MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.74475928
29TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74221621
30* GATA2_19941826_ChIP-Seq_K562_Human1.73404225
31E2F1_21310950_ChIP-Seq_MCF-7_Human1.72484417
32* TCF7_22412390_ChIP-Seq_EML_Mouse1.72334228
33* XRN2_22483619_ChIP-Seq_HELA_Human1.71854069
34* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.69647191
35TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69592105
36TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.68964136
37IRF8_27001747_Chip-Seq_BMDM_Mouse1.65564941
38* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.63452626
39AR_21909140_ChIP-Seq_LNCAP_Human1.61609237
40* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.61363105
41UTX_26944678_Chip-Seq_JUKART_Human1.60641499
42SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.60380066
43SALL4_18804426_ChIP-ChIP_XEN_Mouse1.60190231
44MYC_18358816_ChIP-ChIP_MESCs_Mouse1.56893157
45KDM2B_26808549_Chip-Seq_DND41_Human1.53266672
46CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.53101190
47* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.52008358
48* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.51592545
49* ELK3_25401928_ChIP-Seq_HUVEC_Human1.50529946
50MAF_26560356_Chip-Seq_TH1_Human1.50399800
51CLOCK_20551151_ChIP-Seq_293T_Human1.50043529
52CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.48993255
53ZFX_18555785_ChIP-Seq_MESCs_Mouse1.48717459
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.48489842
55GATA1_19941827_ChIP-Seq_MEL_Mouse1.48225726
56KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.48149985
57SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.47513954
58SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.47513954
59FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.46626093
60BRD4_25478319_ChIP-Seq_HGPS_Human1.45884982
61ELF1_17652178_ChIP-ChIP_JURKAT_Human1.45102687
62KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.42814593
63SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.42613480
64TFEB_21752829_ChIP-Seq_HELA_Human1.42265683
65IRF8_21731497_ChIP-ChIP_J774_Mouse1.42111543
66SCL_19346495_ChIP-Seq_HPC-7_Human1.39436937
67* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.39186443
68SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37126413
69* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.37011429
70STAT4_19710469_ChIP-ChIP_TH1__Mouse1.35853556
71RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.35662691
72P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35211697
73PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.34845314
74FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.34544509
75ZNF263_19887448_ChIP-Seq_K562_Human1.32777969
76PU_27001747_Chip-Seq_BMDM_Mouse1.32644347
77HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.31466089
78* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.30590816
79KDM5A_27292631_Chip-Seq_BREAST_Human1.30365460
80SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.29948321
81TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.28562978
82DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.28134025
83RUNX_20019798_ChIP-Seq_JUKART_Human1.28077587
84VDR_24763502_ChIP-Seq_THP-1_Human1.27385143
85STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.27370070
86SPI1_23547873_ChIP-Seq_NB4_Human1.25967617
87GABP_19822575_ChIP-Seq_HepG2_Human1.25076427
88TRIM28_21343339_ChIP-Seq_HEK293_Human1.25042569
89MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.25038311
90* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.23968106
91IRF8_22096565_ChIP-ChIP_GC-B_Human1.23467861
92ETS1_20019798_ChIP-Seq_JURKAT_Human1.23372505
93CREB1_15753290_ChIP-ChIP_HEK293T_Human1.22958305
94RUNX1_22412390_ChIP-Seq_EML_Mouse1.22516670
95POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.22176221
96KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.22005434
97GATA2_22383799_ChIP-Seq_G1ME_Mouse1.21741559
98POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.20871780
99MYB_26560356_Chip-Seq_TH2_Human1.20870432
100ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.20723995
101* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.20424294
102* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.20320099
103NANOG_18555785_ChIP-Seq_MESCs_Mouse1.20281011
104STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.19573992
105MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.19320844
106NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.18269713
107* FOXP3_21729870_ChIP-Seq_TREG_Human1.17629645
108WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.16915600
109ESR1_15608294_ChIP-ChIP_MCF-7_Human1.16480437
110HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.16462222
111KDM2B_26808549_Chip-Seq_SUP-B15_Human1.14705218
112TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.13611152
113HOXB4_20404135_ChIP-ChIP_EML_Mouse1.13049099
114NCOR1_26117541_ChIP-Seq_K562_Human1.12725300
115MYB_26560356_Chip-Seq_TH1_Human1.12724655
116UBF1/2_26484160_Chip-Seq_HMECs_Human1.12124921
117* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12106877
118VDR_23849224_ChIP-Seq_CD4+_Human1.11931840
119STAT3_1855785_ChIP-Seq_MESCs_Mouse1.11165542
120GATA1_22383799_ChIP-Seq_G1ME_Mouse1.11042714
121E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.10581634
122E2F1_18555785_ChIP-Seq_MESCs_Mouse1.09455127
123E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.09135282
124KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.08890080
125RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.08562434
126HIF1A_21447827_ChIP-Seq_MCF-7_Human1.07685877
127IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.07143251
128SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.06986879
129* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.06943373
130ZFP281_18757296_ChIP-ChIP_E14_Mouse1.06426517
131* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.06306605
132TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.04581073
133NANOG_21062744_ChIP-ChIP_HESCs_Human1.04517249
134EST1_17652178_ChIP-ChIP_JURKAT_Human1.04131751
135CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.03945198
136CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.03659978
137* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03201977
138* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.02382288
139* ATF3_27146783_Chip-Seq_COLON_Human1.02275220
140DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.02129019
141GATA1_22025678_ChIP-Seq_K562_Human1.02082057
142KDM2B_26808549_Chip-Seq_JURKAT_Human1.01863309
143FOXO3_23340844_ChIP-Seq_DLD1_Human1.01742423
144ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.01349627
145DCP1A_22483619_ChIP-Seq_HELA_Human1.00363189
146* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.00359698
147GABP_17652178_ChIP-ChIP_JURKAT_Human0.99816460
148LXR_22292898_ChIP-Seq_THP-1_Human0.98028639
149ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97786513
150KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97038779
151TTF2_22483619_ChIP-Seq_HELA_Human0.96224308
152SPI1_23127762_ChIP-Seq_K562_Human0.95371882
153CHD1_26751641_Chip-Seq_LNCaP_Human0.95357223
154YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.95124366

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology3.06507739
2MP0003693_abnormal_embryo_hatching2.89812909
3MP0003303_peritoneal_inflammation2.85258025
4MP0003705_abnormal_hypodermis_morpholog2.80041906
5MP0010352_gastrointestinal_tract_polyps2.72468443
6MP0010094_abnormal_chromosome_stability2.71068437
7MP0006054_spinal_hemorrhage2.68042211
8MP0003077_abnormal_cell_cycle2.61305801
9MP0002396_abnormal_hematopoietic_system2.54055630
10MP0005076_abnormal_cell_differentiation2.51731155
11MP0010307_abnormal_tumor_latency2.50035569
12MP0003123_paternal_imprinting2.47295272
13MP0004957_abnormal_blastocyst_morpholog2.33187586
14MP0005257_abnormal_intraocular_pressure2.29242653
15MP0004808_abnormal_hematopoietic_stem2.19323160
16MP0005058_abnormal_lysosome_morphology2.11848953
17MP0008007_abnormal_cellular_replicative2.09069451
18MP0009278_abnormal_bone_marrow2.06997425
19MP0004272_abnormal_basement_membrane2.03833952
20MP0002877_abnormal_melanocyte_morpholog1.96749334
21MP0001730_embryonic_growth_arrest1.89227994
22MP0000350_abnormal_cell_proliferation1.87024759
23MP0005451_abnormal_body_composition1.85382362
24MP0001958_emphysema1.85254255
25MP0003300_gastrointestinal_ulcer1.85248834
26MP0003566_abnormal_cell_adhesion1.84060082
27MP0001545_abnormal_hematopoietic_system1.77671072
28MP0005397_hematopoietic_system_phenotyp1.77671072
29MP0008438_abnormal_cutaneous_collagen1.73652098
30MP0005171_absent_coat_pigmentation1.63234410
31MP0009053_abnormal_anal_canal1.61392174
32MP0003828_pulmonary_edema1.60984278
33MP0003656_abnormal_erythrocyte_physiolo1.58228597
34MP0003950_abnormal_plasma_membrane1.56009702
35MP0003724_increased_susceptibility_to1.55702740
36MP0003191_abnormal_cellular_cholesterol1.54550409
37MP0000569_abnormal_digit_pigmentation1.53639753
38MP0003436_decreased_susceptibility_to1.51917582
39MP0004197_abnormal_fetal_growth/weight/1.51527922
40MP0003984_embryonic_growth_retardation1.49914864
41MP0001697_abnormal_embryo_size1.48577467
42MP0002088_abnormal_embryonic_growth/wei1.47325309
43MP0002398_abnormal_bone_marrow1.47233061
44MP0001672_abnormal_embryogenesis/_devel1.45735047
45MP0005380_embryogenesis_phenotype1.45735047
46MP0002080_prenatal_lethality1.43456959
47MP0001915_intracranial_hemorrhage1.40996201
48MP0000767_abnormal_smooth_muscle1.40934058
49MP0008004_abnormal_stomach_pH1.39908126
50MP0010234_abnormal_vibrissa_follicle1.38670082
51MP0002086_abnormal_extraembryonic_tissu1.37256308
52MP0000343_altered_response_to1.37250568
53MP0002019_abnormal_tumor_incidence1.36667209
54MP0002009_preneoplasia1.32841158
55MP0005023_abnormal_wound_healing1.32209057
56MP0003221_abnormal_cardiomyocyte_apopto1.28252159
57MP0000858_altered_metastatic_potential1.27984865
58MP0005464_abnormal_platelet_physiology1.27878490
59MP0005623_abnormal_meninges_morphology1.27775454
60MP0003279_aneurysm1.26737144
61MP0003121_genomic_imprinting1.25844790
62MP0002084_abnormal_developmental_patter1.24688980
63MP0008260_abnormal_autophagy1.24601641
64MP0002722_abnormal_immune_system1.20993564
65MP0002060_abnormal_skin_morphology1.19952364
66MP0000703_abnormal_thymus_morphology1.17733348
67MP0001849_ear_inflammation1.17500495
68MP0000490_abnormal_crypts_of1.17125481
69MP0003567_abnormal_fetal_cardiomyocyte1.16707831
70MP0002085_abnormal_embryonic_tissue1.14136568
71MP0000689_abnormal_spleen_morphology1.12376579
72MP0009672_abnormal_birth_weight1.12038453
73MP0008961_abnormal_basal_metabolism1.11267060
74MP0004185_abnormal_adipocyte_glucose1.09686477
75MP0002429_abnormal_blood_cell1.09209933
76MP0000313_abnormal_cell_death1.08371747
77MP0002089_abnormal_postnatal_growth/wei1.08036810
78MP0003172_abnormal_lysosome_physiology1.07402677
79MP0003091_abnormal_cell_migration1.07366279
80MP0000465_gastrointestinal_hemorrhage1.06629631
81MP0002998_abnormal_bone_remodeling1.06621467
82MP0008058_abnormal_DNA_repair1.06406887
83MP0005000_abnormal_immune_tolerance1.06403169
84MP0000015_abnormal_ear_pigmentation1.03669821
85MP0000733_abnormal_muscle_development1.03437822
86MP0001879_abnormal_lymphatic_vessel1.01094253
87MP0000716_abnormal_immune_system0.98600915
88MP0000003_abnormal_adipose_tissue0.97913149
89MP0005621_abnormal_cell_physiology0.97886608
90MP0003453_abnormal_keratinocyte_physiol0.97867739
91MP0008932_abnormal_embryonic_tissue0.97762740
92MP0004510_myositis0.97491078
93MP0002420_abnormal_adaptive_immunity0.97079901
94MP0001819_abnormal_immune_cell0.95687078
95MP0005409_darkened_coat_color0.92874781
96MP0005083_abnormal_biliary_tract0.92050546
97MP0005503_abnormal_tendon_morphology0.92008282
98MP0003283_abnormal_digestive_organ0.91455927
99MP0005384_cellular_phenotype0.91242097
100MP0001851_eye_inflammation0.90348531
101MP0009333_abnormal_splenocyte_physiolog0.90335486
102MP0002452_abnormal_antigen_presenting0.89962733
103MP0001243_abnormal_dermal_layer0.89931389
104MP0002128_abnormal_blood_circulation0.88546597
105MP0003183_abnormal_peptide_metabolism0.88378889
106MP0003448_altered_tumor_morphology0.87664661
107MP0000013_abnormal_adipose_tissue0.87178287
108MP0002166_altered_tumor_susceptibility0.86722142
109MP0010030_abnormal_orbit_morphology0.86474140
110MP0001800_abnormal_humoral_immune0.86368032
111MP0008057_abnormal_DNA_replication0.86022010
112MP0002925_abnormal_cardiovascular_devel0.85918791
113MP0002006_tumorigenesis0.85871401
114MP0000358_abnormal_cell_content/0.84789929
115MP0001533_abnormal_skeleton_physiology0.84552299
116MP0000249_abnormal_blood_vessel0.84049324
117MP0009703_decreased_birth_body0.84044248
118MP0009840_abnormal_foam_cell0.83788042
119MP0001853_heart_inflammation0.83373056
120MP0005165_increased_susceptibility_to0.82724225
121MP0005375_adipose_tissue_phenotype0.82174486
122MP0003795_abnormal_bone_structure0.82072765
123MP0002419_abnormal_innate_immunity0.81563543
124MP0001835_abnormal_antigen_presentation0.81441094
125MP0005666_abnormal_adipose_tissue0.81293773
126MP0005408_hypopigmentation0.81086419
127MP0003122_maternal_imprinting0.80584756
128MP0004233_abnormal_muscle_weight0.80500127
129MP0005164_abnormal_response_to0.79832220
130MP0002896_abnormal_bone_mineralization0.79424351
131MP0000537_abnormal_urethra_morphology0.78907125
132MP0003763_abnormal_thymus_physiology0.78840704
133MP0004947_skin_inflammation0.78251101
134MP0009763_increased_sensitivity_to0.78024556
135MP0008770_decreased_survivor_rate0.78008571
136MP0000685_abnormal_immune_system0.77409609
137MP0000428_abnormal_craniofacial_morphol0.76958923
138MP0002970_abnormal_white_adipose0.75373414
139MP0003045_fibrosis0.75338135
140MP0006138_congestive_heart_failure0.75204025
141MP0002405_respiratory_system_inflammati0.75079990
142MP0005275_abnormal_skin_tensile0.74245014
143MP0000371_diluted_coat_color0.74189024
144MP0000266_abnormal_heart_morphology0.73249343
145MP0001614_abnormal_blood_vessel0.72989271
146MP0010368_abnormal_lymphatic_system0.71824326
147MP0004084_abnormal_cardiac_muscle0.71734867

Predicted human phenotypes

RankGene SetZ-score
1Menorrhagia (HP:0000132)4.30608583
2Prolonged bleeding time (HP:0003010)3.77010155
3Aortic dissection (HP:0002647)3.58732375
4Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.42545319
5Short 4th metacarpal (HP:0010044)3.42545319
6Hyperacusis (HP:0010780)3.31309986
7Epistaxis (HP:0000421)3.17394231
8Gingival bleeding (HP:0000225)3.14725851
9Abnormality of the common coagulation pathway (HP:0010990)3.00217001
10Osteolytic defects of the phalanges of the hand (HP:0009771)2.98007735
11Osteolytic defects of the hand bones (HP:0009699)2.98007735
12Cerebral aneurysm (HP:0004944)2.96691647
13Myocardial infarction (HP:0001658)2.93213464
14Arterial tortuosity (HP:0005116)2.88552400
15Purpura (HP:0000979)2.81639688
16Vascular tortuosity (HP:0004948)2.75920499
17Abnormality of the 4th metacarpal (HP:0010012)2.75546363
18Abnormal platelet function (HP:0011869)2.74220956
19Impaired platelet aggregation (HP:0003540)2.74220956
20Petechiae (HP:0000967)2.70172073
21Protrusio acetabuli (HP:0003179)2.68860019
22Ankle contracture (HP:0006466)2.61154171
23Polycythemia (HP:0001901)2.61122995
24Spondylolisthesis (HP:0003302)2.59821022
25Vertebral compression fractures (HP:0002953)2.54903904
26Broad palm (HP:0001169)2.53519529
27Abnormality of the calcaneus (HP:0008364)2.45774960
28Increased density of long bones (HP:0006392)2.39614442
29Cutaneous melanoma (HP:0012056)2.39075555
30Mitral stenosis (HP:0001718)2.38906293
31Wormian bones (HP:0002645)2.38667285
32Cellulitis (HP:0100658)2.35922314
33Fatigue (HP:0012378)2.34563776
34Thrombocytosis (HP:0001894)2.34531779
35Shallow orbits (HP:0000586)2.33900499
36Relative macrocephaly (HP:0004482)2.32446627
37Ependymoma (HP:0002888)2.32366166
38Renal duplication (HP:0000075)2.29723143
39Increased nuchal translucency (HP:0010880)2.29020991
40Insomnia (HP:0100785)2.28863282
41High pitched voice (HP:0001620)2.28809355
42Slender long bone (HP:0003100)2.27064307
43Hand muscle atrophy (HP:0009130)2.26792706
44Soft skin (HP:0000977)2.25484761
45Blue sclerae (HP:0000592)2.25288709
46Bowel diverticulosis (HP:0005222)2.24689963
47Dilatation of the ascending aorta (HP:0005111)2.24590095
48Bruising susceptibility (HP:0000978)2.19399565
49Cortical dysplasia (HP:0002539)2.14097248
50Metaphyseal cupping (HP:0003021)2.08779185
51Long toe (HP:0010511)2.08523064
52Pelvic girdle muscle weakness (HP:0003749)2.06965967
53Spinal cord lesions (HP:0100561)2.02697773
54Syringomyelia (HP:0003396)2.02697773
55Termporal pattern (HP:0011008)2.02274000
56Insidious onset (HP:0003587)2.02274000
57Eczematoid dermatitis (HP:0000976)2.02137264
58Disproportionate tall stature (HP:0001519)2.01924696
59Cervical subluxation (HP:0003308)2.01464057
60Asymmetry of the thorax (HP:0001555)2.00898726
61Genu recurvatum (HP:0002816)2.00829982
62Hematochezia (HP:0002573)2.00595695
63Abnormality of the peritoneum (HP:0002585)2.00492053
64Atrophy/Degeneration involving motor neurons (HP:0007373)1.99141128
65Subacute progressive viral hepatitis (HP:0006572)1.99122647
66Pointed chin (HP:0000307)1.98384253
67Renovascular hypertension (HP:0100817)1.96930072
68Fragile skin (HP:0001030)1.96187563
69Atrophic scars (HP:0001075)1.96078129
70Distal lower limb amyotrophy (HP:0008944)1.95331234
71Degeneration of anterior horn cells (HP:0002398)1.95251697
72Abnormality of the anterior horn cell (HP:0006802)1.95251697
73Multiple enchondromatosis (HP:0005701)1.94725677
74Nonimmune hydrops fetalis (HP:0001790)1.94208167
75Selective tooth agenesis (HP:0001592)1.94089691
76Enlarged penis (HP:0000040)1.93351502
77Papilledema (HP:0001085)1.93278334
78Orthostatic hypotension (HP:0001278)1.92669031
79Hyperextensible skin (HP:0000974)1.90981362
80Abnormal delivery (HP:0001787)1.90913907
81Hypoplasia of the iris (HP:0007676)1.90716418
82Bladder diverticulum (HP:0000015)1.89674043
83Elfin facies (HP:0004428)1.89613986
84Papillary thyroid carcinoma (HP:0002895)1.87007580
85Chest pain (HP:0100749)1.86671766
86Deep philtrum (HP:0002002)1.85973046
87Aneurysm (HP:0002617)1.85707471
88Shoulder girdle muscle weakness (HP:0003547)1.85503871
89Abnormality of the lower motor neuron (HP:0002366)1.85459334
90Basal cell carcinoma (HP:0002671)1.85142291
91Venous abnormality (HP:0002624)1.85015318
92Dysostosis multiplex (HP:0000943)1.84404940
93Increased connective tissue (HP:0009025)1.84395615
94Peritonitis (HP:0002586)1.84292653
95Spinal rigidity (HP:0003306)1.81987923
96Abnormality of skull ossification (HP:0002703)1.81969812
97Joint laxity (HP:0001388)1.81829816
98Upper limb amyotrophy (HP:0009129)1.81271054
99Distal upper limb amyotrophy (HP:0007149)1.81271054
100Coarse hair (HP:0002208)1.81033615
101Amyotrophic lateral sclerosis (HP:0007354)1.80563495
102Back pain (HP:0003418)1.80535167
103IgM deficiency (HP:0002850)1.80242211
104Ulnar deviation of the wrist (HP:0003049)1.79338385
105Angiofibromas (HP:0010615)1.77666408
106Adenoma sebaceum (HP:0009720)1.77666408
107Spontaneous hematomas (HP:0007420)1.77546814
108Abnormality of the acetabulum (HP:0003170)1.76869885
109Aortic aneurysm (HP:0004942)1.75801929
110Deviation of the thumb (HP:0009603)1.75768979
111Abnormality of oral frenula (HP:0000190)1.75726342
112Abnormal neuron morphology (HP:0012757)1.75673635
113Abnormality of the motor neurons (HP:0002450)1.75673635
114Lymphangioma (HP:0100764)1.74940249
115Bicuspid aortic valve (HP:0001647)1.74021926
116Astrocytoma (HP:0009592)1.73749622
117Abnormality of the astrocytes (HP:0100707)1.73749622
118Hemorrhage of the eye (HP:0011885)1.73666752
119Wrist flexion contracture (HP:0001239)1.73658003
120Thin bony cortex (HP:0002753)1.73319975
121Decreased skull ossification (HP:0004331)1.72812764
122Abnormality of the Achilles tendon (HP:0005109)1.72038823
123Volvulus (HP:0002580)1.72015329
124Recurrent abscess formation (HP:0002722)1.71922533
125Amaurosis fugax (HP:0100576)1.71288632
126Exostoses (HP:0100777)1.70051574
127Biconcave vertebral bodies (HP:0004586)1.69938973
128Fibrous tissue neoplasm (HP:0012316)1.69834512
129Mitral valve prolapse (HP:0001634)1.69804018
130Upper limb muscle weakness (HP:0003484)1.69197027
131Prominent nose (HP:0000448)1.68499697
132Delayed closure of the anterior fontanelle (HP:0001476)1.68345152
133Tetraparesis (HP:0002273)1.68125447
134Proximal placement of thumb (HP:0009623)1.67535257
135Striae distensae (HP:0001065)1.67375041
136Abnormality of the metopic suture (HP:0005556)1.66965490
137Papilloma (HP:0012740)1.66474686
138Verrucae (HP:0200043)1.66474686
139Breech presentation (HP:0001623)1.66295482
140Mitral regurgitation (HP:0001653)1.66159509
141Missing ribs (HP:0000921)1.66053145
142Fibroma (HP:0010614)1.65207296
143Acanthocytosis (HP:0001927)1.64930486
144Absent frontal sinuses (HP:0002688)1.64540566
145Diminished motivation (HP:0000745)1.64511691
146Prominent metopic ridge (HP:0005487)1.64399546
147Abnormal platelet volume (HP:0011876)1.64230587
148Achilles tendon contracture (HP:0001771)1.63817770
149Increased variability in muscle fiber diameter (HP:0003557)1.63661227
150Arterial thrombosis (HP:0004420)1.63572038
151Abnormality of skeletal muscle fiber size (HP:0012084)1.62481593
152Abnormality of the heme biosynthetic pathway (HP:0010472)1.62360722
153Poikilocytosis (HP:0004447)1.61731665
154Colon cancer (HP:0003003)1.61405551
155Premature rupture of membranes (HP:0001788)1.61356883
156Overlapping toe (HP:0001845)1.59909724
157Recurrent viral infections (HP:0004429)1.59718568
158Intestinal polyp (HP:0005266)1.59558665
159Spastic diplegia (HP:0001264)1.59031709
160Overgrowth (HP:0001548)1.59026100
161Mucopolysacchariduria (HP:0008155)1.58226412
162Urinary glycosaminoglycan excretion (HP:0003541)1.58226412
163Dislocated radial head (HP:0003083)1.57886991
164Abnormality of the musculature of the pelvis (HP:0001469)1.57820348
165Abnormality of the hip-girdle musculature (HP:0001445)1.57820348
166Short nail (HP:0001799)1.57061284
167Venous insufficiency (HP:0005293)1.56599885
168Cutis marmorata (HP:0000965)1.56564191
169Cupped ribs (HP:0000887)1.55987132
170Ulnar bowing (HP:0003031)1.55628924
171Persistence of primary teeth (HP:0006335)1.55018762
172Intestinal polyposis (HP:0200008)1.54967385
173Increased mean platelet volume (HP:0011877)1.54606284
174Broad face (HP:0000283)1.53973817
175Radial bowing (HP:0002986)1.53839723
176Ankyloglossia (HP:0010296)1.53802553
177Interstitial pulmonary disease (HP:0006530)1.53292746

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PKN24.20027841
2TRIB33.91588649
3EEF2K3.55634159
4PRPF4B3.26436984
5IRAK33.08453434
6MAP3K102.71543538
7SCYL22.43174428
8RIPK42.38036157
9BUB12.29488114
10NEK12.26297514
11ERN12.24761778
12NEK22.21025276
13ICK2.17621043
14CDC72.15487560
15MAP3K142.11185659
16MAP3K62.01888818
17EIF2AK11.81355473
18WEE11.76596486
19FLT31.75482450
20BMPR21.75348814
21TESK21.73709346
22MAP4K11.67346099
23RPS6KA41.64517195
24PTK61.63958702
25MAP3K131.59427295
26TESK11.59152089
27STK101.57650150
28LRRK21.57356797
29PAK41.57325999
30MYLK1.55801638
31DDR21.54866880
32TTN1.52608181
33PIK3CG1.51056725
34KDR1.49240363
35BMX1.47608763
36PASK1.46670501
37BRSK21.41230585
38TGFBR11.40344825
39MAPKAPK31.38302994
40ALK1.38279667
41PDGFRA1.36555202
42JAK11.34324943
43TRPM71.31323918
44TAOK21.30890057
45CDK121.30642490
46RPS6KB21.30044669
47MAP3K81.28720529
48BRSK11.26272052
49MAP2K31.20284559
50GRK61.17110498
51TSSK61.15414735
52RIPK11.13912561
53PDGFRB1.12170339
54DYRK31.02866163
55ACVR1B1.01695011
56KSR20.96441651
57MOS0.96300758
58BTK0.95926744
59CDK40.90335802
60CDK60.88004832
61IRAK10.87582557
62ATR0.84560221
63ILK0.83485622
64HIPK20.83231939
65MAP3K30.82786601
66SMG10.82477016
67STK240.81619175
68MTOR0.80517106
69PTK2B0.80361755
70LIMK10.79365852
71NEK90.79320494
72PLK10.79271893
73KSR10.78095398
74IRAK20.78082128
75MAP3K10.77001746
76IRAK40.74728387
77PIM10.73416699
78WNK10.73149080
79CSK0.72849404
80TEC0.71842260
81FGFR40.71639829
82LATS10.71076125
83LATS20.69717469
84MAP3K90.69333823
85SIK30.69166761
86TTK0.68418433
87AURKB0.66847341
88ZAP700.66430848
89RAF10.65620063
90CDK70.65574426
91RET0.64386456
92ARAF0.64006482
93MAP3K110.62231026
94STK30.61746865
95CHEK10.60873051
96MAP3K20.60526396
97MKNK10.60218406
98TAOK10.59546793
99PDPK10.59283038
100FGR0.59195229
101TYK20.58644523
102FGFR10.58299584
103CDC42BPA0.57702004
104YES10.57658576
105BRD40.56419676
106PAK20.56063397
107RPS6KA20.56005667
108ERBB30.54300094
109MARK30.54288169
110EPHB10.54089136
111HCK0.52935095
112JAK20.52882856
113EPHA30.52239587
114STK40.51367387
115DAPK10.50804412
116STK380.50090332
117SYK0.49698329
118FER0.49617737
119CAMKK10.49526216
120JAK30.48816267
121FES0.48596610
122BLK0.48558023
123CDK20.48165329
124PLK30.47790565
125PTK20.47231807
126MAP2K10.46635485
127PRKD20.45717250
128ITK0.45612861
129MAPK110.45582699
130SGK30.45261907
131SRPK10.44144200
132TGFBR20.43851619
133PDK10.42845247
134EIF2AK30.42688139
135CSF1R0.42348717
136ERBB40.42121965
137DYRK1B0.41791313
138TBK10.41088060
139CHEK20.39855904
140CLK10.39810853
141SIK10.39718852
142MAP3K50.39254082
143STK38L0.39059797
144MKNK20.39027879
145FGFR30.37091628
146PAK10.36248041
147CAMKK20.35290360
148PIM20.35169786

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.08427434
2Cell cycle_Homo sapiens_hsa041102.40877433
3Spliceosome_Homo sapiens_hsa030402.17738883
4RNA transport_Homo sapiens_hsa030132.04931662
5Base excision repair_Homo sapiens_hsa034102.01342550
6Mismatch repair_Homo sapiens_hsa034302.00463666
7Chronic myeloid leukemia_Homo sapiens_hsa052201.91625136
8Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.68692206
9Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.67183118
10ECM-receptor interaction_Homo sapiens_hsa045121.65355791
11Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.59421539
12Other glycan degradation_Homo sapiens_hsa005111.57172055
13One carbon pool by folate_Homo sapiens_hsa006701.55370051
14mTOR signaling pathway_Homo sapiens_hsa041501.50523403
15Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.48781880
16p53 signaling pathway_Homo sapiens_hsa041151.47577474
17Non-small cell lung cancer_Homo sapiens_hsa052231.44627410
18Viral carcinogenesis_Homo sapiens_hsa052031.44368226
19mRNA surveillance pathway_Homo sapiens_hsa030151.42304614
20Neurotrophin signaling pathway_Homo sapiens_hsa047221.39684455
21Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.39384647
22Central carbon metabolism in cancer_Homo sapiens_hsa052301.39342409
23Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.38045905
24Malaria_Homo sapiens_hsa051441.37499762
25Colorectal cancer_Homo sapiens_hsa052101.36009191
26Nucleotide excision repair_Homo sapiens_hsa034201.34484761
27Pancreatic cancer_Homo sapiens_hsa052121.32407049
28B cell receptor signaling pathway_Homo sapiens_hsa046621.31877599
29Leishmaniasis_Homo sapiens_hsa051401.30829934
30Toll-like receptor signaling pathway_Homo sapiens_hsa046201.29700452
31Antigen processing and presentation_Homo sapiens_hsa046121.29464708
32Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.28083248
33Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.25640133
34Acute myeloid leukemia_Homo sapiens_hsa052211.22906576
35Oocyte meiosis_Homo sapiens_hsa041141.20641700
36VEGF signaling pathway_Homo sapiens_hsa043701.19802956
37Small cell lung cancer_Homo sapiens_hsa052221.18922312
38Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.18524908
39Legionellosis_Homo sapiens_hsa051341.17016365
40Thyroid cancer_Homo sapiens_hsa052161.16867900
41Epstein-Barr virus infection_Homo sapiens_hsa051691.16182969
42Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.15093903
43Hepatitis B_Homo sapiens_hsa051611.14620469
44HTLV-I infection_Homo sapiens_hsa051661.14243930
45MicroRNAs in cancer_Homo sapiens_hsa052061.13968396
46Endometrial cancer_Homo sapiens_hsa052131.13060087
47Bladder cancer_Homo sapiens_hsa052191.12361699
48Shigellosis_Homo sapiens_hsa051311.11611604
49NF-kappa B signaling pathway_Homo sapiens_hsa040641.11481649
50Apoptosis_Homo sapiens_hsa042101.09547167
51Glioma_Homo sapiens_hsa052141.07539993
52Viral myocarditis_Homo sapiens_hsa054161.06889635
53Pentose phosphate pathway_Homo sapiens_hsa000301.06444117
54Leukocyte transendothelial migration_Homo sapiens_hsa046701.04367975
55TNF signaling pathway_Homo sapiens_hsa046681.04202837
56Herpes simplex infection_Homo sapiens_hsa051681.03632254
57Regulation of actin cytoskeleton_Homo sapiens_hsa048101.02406536
58Proteoglycans in cancer_Homo sapiens_hsa052050.99754061
59Osteoclast differentiation_Homo sapiens_hsa043800.99611775
60Insulin resistance_Homo sapiens_hsa049310.99203285
61Insulin signaling pathway_Homo sapiens_hsa049100.97935209
62Salmonella infection_Homo sapiens_hsa051320.96194052
63Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.95694205
64Jak-STAT signaling pathway_Homo sapiens_hsa046300.94019080
65HIF-1 signaling pathway_Homo sapiens_hsa040660.93367958
66Toxoplasmosis_Homo sapiens_hsa051450.93104228
67Platelet activation_Homo sapiens_hsa046110.91459582
68Homologous recombination_Homo sapiens_hsa034400.90175723
69Systemic lupus erythematosus_Homo sapiens_hsa053220.88852132
70Hepatitis C_Homo sapiens_hsa051600.88642964
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.88371966
72Phospholipase D signaling pathway_Homo sapiens_hsa040720.87341199
73ErbB signaling pathway_Homo sapiens_hsa040120.86992764
74Focal adhesion_Homo sapiens_hsa045100.85972641
75Hematopoietic cell lineage_Homo sapiens_hsa046400.85073847
76Lysine degradation_Homo sapiens_hsa003100.84738517
77Biosynthesis of amino acids_Homo sapiens_hsa012300.84674990
78Sphingolipid signaling pathway_Homo sapiens_hsa040710.82820613
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.82775264
80RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.82514952
81Selenocompound metabolism_Homo sapiens_hsa004500.82057754
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81936935
83Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.80709862
84Phagosome_Homo sapiens_hsa041450.79368596
85Lysosome_Homo sapiens_hsa041420.78986153
86Prion diseases_Homo sapiens_hsa050200.77402952
87Adherens junction_Homo sapiens_hsa045200.76953495
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.75935443
89Transcriptional misregulation in cancer_Homo sapiens_hsa052020.75301745
90FoxO signaling pathway_Homo sapiens_hsa040680.74927610
91Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73220198
92N-Glycan biosynthesis_Homo sapiens_hsa005100.72208328
93Choline metabolism in cancer_Homo sapiens_hsa052310.71795897
94AMPK signaling pathway_Homo sapiens_hsa041520.70714924
95Estrogen signaling pathway_Homo sapiens_hsa049150.70101142
96NOD-like receptor signaling pathway_Homo sapiens_hsa046210.69692397
97Measles_Homo sapiens_hsa051620.69677112
98Pertussis_Homo sapiens_hsa051330.68796111
99Phosphatidylinositol signaling system_Homo sapiens_hsa040700.68448225
100Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68023600
101Complement and coagulation cascades_Homo sapiens_hsa046100.67552598
102Influenza A_Homo sapiens_hsa051640.66131596
103Notch signaling pathway_Homo sapiens_hsa043300.65682765
104Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65511110
105Inositol phosphate metabolism_Homo sapiens_hsa005620.64330504
106Renal cell carcinoma_Homo sapiens_hsa052110.64308874
107Melanoma_Homo sapiens_hsa052180.64164817
108Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63909529
109Glycosaminoglycan degradation_Homo sapiens_hsa005310.63687042
110PI3K-Akt signaling pathway_Homo sapiens_hsa041510.63523336
111RNA degradation_Homo sapiens_hsa030180.60728178
112Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.60079857
113Tuberculosis_Homo sapiens_hsa051520.59789884
114Endocytosis_Homo sapiens_hsa041440.58566098
115Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.58219525
116Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57492639
117Carbon metabolism_Homo sapiens_hsa012000.56658646
118Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.56540409
119GnRH signaling pathway_Homo sapiens_hsa049120.56447687
120Primary immunodeficiency_Homo sapiens_hsa053400.55635144
121Proteasome_Homo sapiens_hsa030500.55434302
122Prolactin signaling pathway_Homo sapiens_hsa049170.54778176
123Alcoholism_Homo sapiens_hsa050340.53798209
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53262921
125Dorso-ventral axis formation_Homo sapiens_hsa043200.52818847
126Hippo signaling pathway_Homo sapiens_hsa043900.51963090
127Gap junction_Homo sapiens_hsa045400.51758288
128Chemokine signaling pathway_Homo sapiens_hsa040620.51432940
129SNARE interactions in vesicular transport_Homo sapiens_hsa041300.50308797
130Pathways in cancer_Homo sapiens_hsa052000.50167782
131Non-homologous end-joining_Homo sapiens_hsa034500.49635489
132Glucagon signaling pathway_Homo sapiens_hsa049220.49428671
133Staphylococcus aureus infection_Homo sapiens_hsa051500.49247226
134Prostate cancer_Homo sapiens_hsa052150.48783249
135T cell receptor signaling pathway_Homo sapiens_hsa046600.48223236
136Amoebiasis_Homo sapiens_hsa051460.46636535

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