KCTD9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane repair (GO:0001778)6.20051906
2negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.55799193
3sarcomere organization (GO:0045214)5.35988250
4muscle filament sliding (GO:0030049)5.28203628
5actin-myosin filament sliding (GO:0033275)5.28203628
6regulation of skeletal muscle contraction (GO:0014819)4.64766071
7actin-mediated cell contraction (GO:0070252)4.59278482
8desmosome organization (GO:0002934)4.52880449
9bundle of His cell to Purkinje myocyte communication (GO:0086069)4.47991083
10negative regulation of potassium ion transmembrane transport (GO:1901380)4.45647932
11positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.45205838
12cell adhesion mediated by integrin (GO:0033627)4.28776499
13myofibril assembly (GO:0030239)4.18637262
14cardiac myofibril assembly (GO:0055003)4.11599419
15mitotic sister chromatid segregation (GO:0000070)3.95667679
16cardiac muscle cell development (GO:0055013)3.86964022
17sister chromatid segregation (GO:0000819)3.81244095
18actin filament-based movement (GO:0030048)3.72417388
19regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.65257396
20cardiac cell development (GO:0055006)3.60594487
21regulation of cardioblast differentiation (GO:0051890)3.49574141
22COPII vesicle coating (GO:0048208)3.48487016
23regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.45191948
24pore complex assembly (GO:0046931)3.43472266
25ventricular cardiac muscle cell development (GO:0055015)3.40345767
26actomyosin structure organization (GO:0031032)3.39650068
27sarcoplasmic reticulum calcium ion transport (GO:0070296)3.39638290
28mitotic metaphase plate congression (GO:0007080)3.37719400
29protein hydroxylation (GO:0018126)3.36750011
30tricarboxylic acid cycle (GO:0006099)3.28405521
31mammary gland epithelial cell proliferation (GO:0033598)3.26135851
32regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.25200324
33hemidesmosome assembly (GO:0031581)3.20937203
34carnitine shuttle (GO:0006853)3.18660602
35COPI coating of Golgi vesicle (GO:0048205)3.17739795
36Golgi transport vesicle coating (GO:0048200)3.17739795
37sequestering of extracellular ligand from receptor (GO:0035581)3.14524743
38negative regulation of DNA repair (GO:0045738)3.10574286
39cardiac muscle tissue morphogenesis (GO:0055008)3.10269129
40cardiac muscle contraction (GO:0060048)3.09662707
41NLS-bearing protein import into nucleus (GO:0006607)3.09637896
42regulation of transforming growth factor beta2 production (GO:0032909)3.08225022
43skeletal muscle adaptation (GO:0043501)3.05162449
44UDP-N-acetylglucosamine metabolic process (GO:0006047)3.04212490
45skeletal muscle contraction (GO:0003009)3.04019349
46regulation of spindle organization (GO:0090224)3.02311116
47regulation of relaxation of muscle (GO:1901077)3.02031254
48nucleobase-containing small molecule interconversion (GO:0015949)3.00642701
49cellular response to vitamin D (GO:0071305)2.99082534
50epithelial cell-cell adhesion (GO:0090136)2.97327201
51regulation of mitotic spindle organization (GO:0060236)2.97049493
52mitotic chromosome condensation (GO:0007076)2.93191735
53striated muscle contraction (GO:0006941)2.92847809
54muscle tissue morphogenesis (GO:0060415)2.92530161
55regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.91965754
56mitotic cytokinesis (GO:0000281)2.91307928
57peptidyl-proline hydroxylation (GO:0019511)2.90324026
58iron ion import (GO:0097286)2.89155241
59regulation of tight junction assembly (GO:2000810)2.88715827
60regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.87356963
61cell-substrate junction assembly (GO:0007044)2.87018862
62nuclear pore complex assembly (GO:0051292)2.85856756
63ribosome assembly (GO:0042255)2.84264228
64carnitine transmembrane transport (GO:1902603)2.82769448
65mesodermal cell differentiation (GO:0048333)2.81998034
66establishment of chromosome localization (GO:0051303)2.81805280
67cellular response to vitamin (GO:0071295)2.80023963
68metaphase plate congression (GO:0051310)2.79419948
69skin morphogenesis (GO:0043589)2.79412857
70ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.77063484
71type B pancreatic cell proliferation (GO:0044342)2.76317482
72fatty acid transmembrane transport (GO:1902001)2.75836212
73mesenchymal-epithelial cell signaling (GO:0060638)2.73431005
74protein localization to chromosome, centromeric region (GO:0071459)2.73155789
75cytoskeleton-dependent cytokinesis (GO:0061640)2.72682940
76regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.71801418
77nucleotide-sugar biosynthetic process (GO:0009226)2.69986072
78regulation of cell communication by electrical coupling (GO:0010649)2.69429320
79regulation of cofactor metabolic process (GO:0051193)2.69165025
80regulation of coenzyme metabolic process (GO:0051196)2.69165025
81heart trabecula formation (GO:0060347)2.68719849
82protein localization to endosome (GO:0036010)2.67782754
83histone-serine phosphorylation (GO:0035404)2.67164876
84ventricular cardiac muscle cell action potential (GO:0086005)2.67102258
85positive regulation of chromosome segregation (GO:0051984)2.66804320
86regulation of p38MAPK cascade (GO:1900744)2.66711406
87kidney mesenchyme development (GO:0072074)2.65932588
88DNA unwinding involved in DNA replication (GO:0006268)2.65203670
89regulation of transforming growth factor beta1 production (GO:0032908)2.63410089
90collagen fibril organization (GO:0030199)2.63384869
91cellular protein complex localization (GO:0034629)2.63162770
92amino-acid betaine transport (GO:0015838)2.61887775
93carnitine transport (GO:0015879)2.61887775
94negative regulation of protein localization to plasma membrane (GO:1903077)2.61833923
95creatine metabolic process (GO:0006600)2.61821868
96hippo signaling (GO:0035329)2.61344768
97cytoplasmic mRNA processing body assembly (GO:0033962)2.61042586
98heart process (GO:0003015)2.57726435
99heart contraction (GO:0060047)2.57726435
100chromosome condensation (GO:0030261)2.57658978
101regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.57013528
102cellular response to zinc ion (GO:0071294)2.56386924
103protein localization to kinetochore (GO:0034501)2.56345533
104kinetochore organization (GO:0051383)2.55967997
105positive regulation of myotube differentiation (GO:0010831)2.55155464
106regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.55096352
107chondrocyte proliferation (GO:0035988)2.54268381
108fusion of sperm to egg plasma membrane (GO:0007342)2.53458801
109AMP metabolic process (GO:0046033)2.53066110
110regulation of early endosome to late endosome transport (GO:2000641)2.52148324
111skeletal muscle tissue regeneration (GO:0043403)2.52059838
112keratinocyte proliferation (GO:0043616)2.50646860
113negative regulation of anoikis (GO:2000811)2.50420303
114mitotic nuclear envelope disassembly (GO:0007077)2.50252694
115positive regulation of p38MAPK cascade (GO:1900745)2.49743774
116fibroblast migration (GO:0010761)2.49463119
1174-hydroxyproline metabolic process (GO:0019471)2.48864607
118nuclear pore organization (GO:0006999)2.48479798
119hepatocyte differentiation (GO:0070365)2.48373688
120muscle contraction (GO:0006936)2.48194172
121nuclear envelope disassembly (GO:0051081)2.47298630
122membrane disassembly (GO:0030397)2.47298630
123regulation of metalloenzyme activity (GO:0048552)2.45889919
124cellular response to arsenic-containing substance (GO:0071243)2.45729625
125DNA packaging (GO:0006323)2.45346658
126negative regulation of keratinocyte proliferation (GO:0010839)2.44987007
127positive regulation of macrophage activation (GO:0043032)2.44704790
128endodermal cell differentiation (GO:0035987)2.44375440
129striated muscle atrophy (GO:0014891)2.44061188
130regulation of actin filament-based movement (GO:1903115)2.44026138
131striated muscle cell development (GO:0055002)2.43107450
132regulation of sequestering of triglyceride (GO:0010889)2.42487927
133cardiac muscle hypertrophy (GO:0003300)2.42103485
134positive regulation of endothelial cell apoptotic process (GO:2000353)2.41394598
135regulation of DNA endoreduplication (GO:0032875)2.41358019
136striated muscle hypertrophy (GO:0014897)2.40548745
137vesicle coating (GO:0006901)2.40199989
138mitotic sister chromatid cohesion (GO:0007064)2.39973904
139atrioventricular valve morphogenesis (GO:0003181)2.39855513
140negative regulation of heart growth (GO:0061117)2.39684618
141negative regulation of cardiac muscle tissue growth (GO:0055022)2.39684618
142regulation of integrin-mediated signaling pathway (GO:2001044)2.39541852
143cell-substrate adherens junction assembly (GO:0007045)2.37409011
144focal adhesion assembly (GO:0048041)2.37409011
145response to muscle activity (GO:0014850)2.36983601
146muscle cell migration (GO:0014812)2.36649173
147substrate-dependent cell migration (GO:0006929)2.36288964
148positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.35873057
149regulation of acyl-CoA biosynthetic process (GO:0050812)2.35431817
150paraxial mesoderm development (GO:0048339)2.35420653
151ER overload response (GO:0006983)2.35388051
152endocardial cushion development (GO:0003197)2.35348948
153regulation of striated muscle contraction (GO:0006942)2.35034906
154cellular response to osmotic stress (GO:0071470)2.34468939
155attachment of spindle microtubules to kinetochore (GO:0008608)2.34422550
156regulation of translational termination (GO:0006449)2.34344804
157negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.33535195
158sprouting angiogenesis (GO:0002040)2.33133689
159hypotonic response (GO:0006971)2.32436100
160positive regulation of protein import into nucleus, translocation (GO:0033160)2.31232874
161dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.31067115
162positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.30075563
163positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.30075563
164positive regulation of mitotic sister chromatid separation (GO:1901970)2.30075563
165metanephric mesenchyme development (GO:0072075)2.29970422
166negative regulation of chondrocyte differentiation (GO:0032331)2.29806488
167membrane raft organization (GO:0031579)2.29699271
168protein heterotetramerization (GO:0051290)2.27954115
169muscle system process (GO:0003012)2.26940952
170wound healing, spreading of epidermal cells (GO:0035313)2.25867556
171regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.25815721
172regulation of protein export from nucleus (GO:0046825)2.25799362

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.87684236
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.19814394
3TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.11009801
4E2F7_22180533_ChIP-Seq_HELA_Human3.63269795
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.27819028
6RARG_19884340_ChIP-ChIP_MEFs_Mouse2.88027018
7TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.68154647
8ZNF263_19887448_ChIP-Seq_K562_Human2.68007004
9PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.65686812
10SMAD_19615063_ChIP-ChIP_OVARY_Human2.63586697
11TRIM28_21343339_ChIP-Seq_HEK293_Human2.48135001
12SALL1_21062744_ChIP-ChIP_HESCs_Human2.46225470
13SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.44012351
14FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.41648202
15AR_21909140_ChIP-Seq_LNCAP_Human2.40802654
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.24313845
17HIF1A_21447827_ChIP-Seq_MCF-7_Human2.23304427
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.16010558
19TBX20_22328084_ChIP-Seq_HEART_Mouse2.06375350
20TBX20_22080862_ChIP-Seq_HEART_Mouse2.06375350
21KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human2.00181191
22ATF3_27146783_Chip-Seq_COLON_Human1.97576399
23SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.95589928
24SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.95589928
25RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.89640910
26TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.85743303
27* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.81465867
28EP300_21415370_ChIP-Seq_HL-1_Mouse1.81004691
29* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.79811268
30PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.76076809
31CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.75252570
32ELK1_19687146_ChIP-ChIP_HELA_Human1.70023338
33RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.69900354
34PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65122258
35* SALL4_18804426_ChIP-ChIP_XEN_Mouse1.64499443
36KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.64436712
37MYB_21317192_ChIP-Seq_ERMYB_Mouse1.62478459
38NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.58300915
39FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.54991413
40PPAR_26484153_Chip-Seq_NCI-H1993_Human1.54662708
41MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.54595301
42CJUN_26792858_Chip-Seq_BT549_Human1.51147052
43FOXO3_23340844_ChIP-Seq_DLD1_Human1.46092801
44CLOCK_20551151_ChIP-Seq_293T_Human1.45577568
45ELK3_25401928_ChIP-Seq_HUVEC_Human1.45503401
46* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.44929989
47ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.44241137
48UBF1/2_26484160_Chip-Seq_HMECs_Human1.42640651
49BRD4_27068464_Chip-Seq_AML-cells_Mouse1.42148755
50CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.40664456
51ESR1_21235772_ChIP-Seq_MCF-7_Human1.36493491
52BRD4_25478319_ChIP-Seq_HGPS_Human1.35798343
53RACK7_27058665_Chip-Seq_MCF-7_Human1.34312050
54GATA6_25053715_ChIP-Seq_YYC3_Human1.34000541
55NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.33304630
56NRF2_20460467_ChIP-Seq_MEFs_Mouse1.33304630
57ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.33190678
58P300_27058665_Chip-Seq_ZR-75-30cells_Human1.32594622
59FOXM1_26456572_ChIP-Seq_MCF-7_Human1.31911260
60JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.30929881
61ESR2_21235772_ChIP-Seq_MCF-7_Human1.26346848
62ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.24949158
63RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.21993029
64SOX9_24532713_ChIP-Seq_HFSC_Mouse1.21992085
65NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.21214025
66* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20472150
67* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.19519585
68TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19412713
69P63_26484246_Chip-Seq_KERATINOCYTES_Human1.19382835
70STAT3_1855785_ChIP-Seq_MESCs_Mouse1.19307113
71HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.19023054
72JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.18947568
73GATA4_21415370_ChIP-Seq_HL-1_Mouse1.18947256
74ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18663864
75Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.18363364
76NELFA_20434984_ChIP-Seq_ESCs_Mouse1.12319942
77RBPJ_22232070_ChIP-Seq_NCS_Mouse1.11015491
78* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.10446506
79E2F4_17652178_ChIP-ChIP_JURKAT_Human1.10278333
80ESR1_20079471_ChIP-ChIP_T-47D_Human1.09357500
81PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.09060924
82ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.08344448
83CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.08316508
84TP53_16413492_ChIP-PET_HCT116_Human1.07678090
85TP53_18474530_ChIP-ChIP_U2OS_Human1.06730351
86PPARG_20887899_ChIP-Seq_3T3-L1_Mouse1.05445670
87STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.04793597
88SOX17_20123909_ChIP-Seq_XEN_Mouse1.04647240
89KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.04525515
90MYC_18555785_ChIP-Seq_MESCs_Mouse1.03368581
91GATA3_24758297_ChIP-Seq_MCF-7_Human1.02885202
92* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.02667876
93TP53_22127205_ChIP-Seq_IMR90_Human1.02196627
94PADI4_21655091_ChIP-ChIP_MCF-7_Human1.02094264
95GATA2_21666600_ChIP-Seq_HMVEC_Human0.99806950
96TFEB_21752829_ChIP-Seq_HELA_Human0.99202411
97ZFX_18555785_ChIP-Seq_MESCs_Mouse0.98624213
98NCOR1_26117541_ChIP-Seq_K562_Human0.98407415
99KDM2B_26808549_Chip-Seq_DND41_Human0.97989534
100DCP1A_22483619_ChIP-Seq_HELA_Human0.96697143
101HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.96670802
102MAF_26560356_Chip-Seq_TH1_Human0.96435249
103WT1_19549856_ChIP-ChIP_CCG9911_Human0.95159821
104* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.94664704
105TCF7_22412390_ChIP-Seq_EML_Mouse0.94522856
106CHD1_26751641_Chip-Seq_LNCaP_Human0.93573506
107GATA4_25053715_ChIP-Seq_YYC3_Human0.91031750
108FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.90616637
109RUNX1_27514584_Chip-Seq_MCF-7_Human0.90351443
110KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.90321534
111* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.89993834
112CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.89902538
113EZH2_27294783_Chip-Seq_NPCs_Mouse0.88610058
114TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.87930158
115STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.87835503
116FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.86562953
117STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.86488390
118SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.84475257
119CDX2_22108803_ChIP-Seq_LS180_Human0.83923479
120SOX2_20726797_ChIP-Seq_SW620_Human0.83550543
121* NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.83547309
122KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.82814715
123CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.81079154
124E2F1_21310950_ChIP-Seq_MCF-7_Human0.80931571
125SOX2_27498859_Chip-Seq_STOMACH_Mouse0.80710289
126DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80624964
127CDX2_19796622_ChIP-Seq_MESCs_Mouse0.80425465
128MYB_26560356_Chip-Seq_TH1_Human0.77873561
129STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.76853986
130TP63_23658742_ChIP-Seq_EP156T_Human0.75353927
131* GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.75039315
132PPARA_22158963_ChIP-Seq_LIVER_Mouse0.74154825
133AUTS2_25519132_ChIP-Seq_293T-REX_Human0.74133091

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog3.99456080
2MP0003646_muscle_fatigue3.54397959
3MP0004084_abnormal_cardiac_muscle3.35212533
4MP0000751_myopathy3.09714101
5MP0000749_muscle_degeneration2.95343448
6MP0010352_gastrointestinal_tract_polyps2.93142140
7MP0002837_dystrophic_cardiac_calcinosis2.87994193
8MP0005275_abnormal_skin_tensile2.69989675
9MP0008438_abnormal_cutaneous_collagen2.68099636
10MP0004036_abnormal_muscle_relaxation2.46051172
11MP0004087_abnormal_muscle_fiber2.35880583
12MP0000750_abnormal_muscle_regeneration2.29511323
13MP0005330_cardiomyopathy2.27555130
14MP0005623_abnormal_meninges_morphology2.15739786
15MP0003566_abnormal_cell_adhesion2.09422267
16MP0004215_abnormal_myocardial_fiber2.05595117
17MP0008775_abnormal_heart_ventricle1.97450897
18MP0010630_abnormal_cardiac_muscle1.96292380
19MP0002877_abnormal_melanocyte_morpholog1.94014073
20MP0009697_abnormal_copulation1.91869123
21MP0002106_abnormal_muscle_physiology1.91852506
22MP0000747_muscle_weakness1.86139577
23MP0002972_abnormal_cardiac_muscle1.78283804
24MP0002269_muscular_atrophy1.75211063
25MP0002060_abnormal_skin_morphology1.68553353
26MP0002796_impaired_skin_barrier1.68530998
27MP0003828_pulmonary_edema1.63042797
28MP0005620_abnormal_muscle_contractility1.62608226
29MP0000759_abnormal_skeletal_muscle1.61997790
30MP0005369_muscle_phenotype1.59241588
31MP0001958_emphysema1.58797294
32MP0004272_abnormal_basement_membrane1.57024982
33MP0001544_abnormal_cardiovascular_syste1.55173943
34MP0005385_cardiovascular_system_phenoty1.55173943
35MP0003279_aneurysm1.55004937
36MP0008057_abnormal_DNA_replication1.50989454
37MP0003221_abnormal_cardiomyocyte_apopto1.49570153
38MP0005257_abnormal_intraocular_pressure1.49532916
39MP0004145_abnormal_muscle_electrophysio1.49457882
40MP0003567_abnormal_fetal_cardiomyocyte1.48670192
41MP0005503_abnormal_tendon_morphology1.48145218
42MP0004130_abnormal_muscle_cell1.45794933
43MP0004484_altered_response_of1.39474232
44MP0003950_abnormal_plasma_membrane1.35506828
45MP0000733_abnormal_muscle_development1.34969955
46MP0010234_abnormal_vibrissa_follicle1.30130075
47MP0004185_abnormal_adipocyte_glucose1.25234265
48MP0010094_abnormal_chromosome_stability1.24833396
49MP0003941_abnormal_skin_development1.24043054
50MP0006138_congestive_heart_failure1.23914850
51MP0005023_abnormal_wound_healing1.22035411
52MP0002332_abnormal_exercise_endurance1.18949170
53MP0009384_cardiac_valve_regurgitation1.18156488
54MP0000003_abnormal_adipose_tissue1.12557848
55MP0003693_abnormal_embryo_hatching1.12132872
56MP0005408_hypopigmentation1.12111875
57MP0001542_abnormal_bone_strength1.11934308
58MP0005076_abnormal_cell_differentiation1.11614809
59MP0004233_abnormal_muscle_weight1.11338952
60MP0000762_abnormal_tongue_morphology1.09181487
61MP0005501_abnormal_skin_physiology1.09153674
62MP0001661_extended_life_span1.08910514
63MP0005666_abnormal_adipose_tissue1.08332927
64MP0003300_gastrointestinal_ulcer1.05608637
65MP0005375_adipose_tissue_phenotype1.04555780
66MP0000013_abnormal_adipose_tissue1.02099061
67MP0005410_abnormal_fertilization1.01973090
68MP0000767_abnormal_smooth_muscle1.01511135
69MP0008932_abnormal_embryonic_tissue0.99846022
70MP0005164_abnormal_response_to0.99235143
71MP0010678_abnormal_skin_adnexa0.97567297
72MP0002108_abnormal_muscle_morphology0.97542798
73MP0000266_abnormal_heart_morphology0.97439312
74MP0010368_abnormal_lymphatic_system0.97172757
75MP0006054_spinal_hemorrhage0.97134736
76MP0000350_abnormal_cell_proliferation0.96298394
77MP0008007_abnormal_cellular_replicative0.94053107
78MP0002009_preneoplasia0.93958047
79MP0005409_darkened_coat_color0.93912125
80MP0003045_fibrosis0.93775371
81MP0001216_abnormal_epidermal_layer0.92902646
82MP0003984_embryonic_growth_retardation0.91993837
83MP0003091_abnormal_cell_migration0.91432352
84MP0002088_abnormal_embryonic_growth/wei0.91256647
85MP0000343_altered_response_to0.88167656
86MP0009053_abnormal_anal_canal0.88029878
87MP0010307_abnormal_tumor_latency0.87340350
88MP0003656_abnormal_erythrocyte_physiolo0.86876127
89MP0001849_ear_inflammation0.85143600
90MP0000627_abnormal_mammary_gland0.84914393
91MP0003191_abnormal_cellular_cholesterol0.84899051
92MP0001879_abnormal_lymphatic_vessel0.84415782
93MP0006036_abnormal_mitochondrial_physio0.83902722
94MP0003453_abnormal_keratinocyte_physiol0.83333645
95MP0004947_skin_inflammation0.83112705
96MP0004957_abnormal_blastocyst_morpholog0.82821153
97MP0005451_abnormal_body_composition0.82649092
98MP0002128_abnormal_blood_circulation0.82582230
99MP0004808_abnormal_hematopoietic_stem0.82443222
100MP0003137_abnormal_impulse_conducting0.81981254
101MP0001299_abnormal_eye_distance/0.81231698
102MP0005380_embryogenesis_phenotype0.79713854
103MP0001672_abnormal_embryogenesis/_devel0.79713854
104MP0005621_abnormal_cell_physiology0.79649434
105MP0004510_myositis0.79579565
106MP0004197_abnormal_fetal_growth/weight/0.78473369
107MP0001730_embryonic_growth_arrest0.78431353
108MP0000427_abnormal_hair_cycle0.76802094
109MP0002295_abnormal_pulmonary_circulatio0.76179245
110MP0003806_abnormal_nucleotide_metabolis0.75809671
111MP0003786_premature_aging0.75539229
112MP0003111_abnormal_nucleus_morphology0.75477778
113MP0005165_increased_susceptibility_to0.75358745
114MP0002166_altered_tumor_susceptibility0.74219856
115MP0000858_altered_metastatic_potential0.73874232
116MP0004134_abnormal_chest_morphology0.73204247
117MP0000579_abnormal_nail_morphology0.73191326
118MP0009278_abnormal_bone_marrow0.72523035
119MP0002925_abnormal_cardiovascular_devel0.72262255
120MP0001243_abnormal_dermal_layer0.71980977
121MP0002006_tumorigenesis0.70428099
122MP0002086_abnormal_extraembryonic_tissu0.70065280
123MP0001881_abnormal_mammary_gland0.68554203
124MP0002396_abnormal_hematopoietic_system0.67845978
125MP0001697_abnormal_embryo_size0.66659757
126MP0002896_abnormal_bone_mineralization0.65646121
127MP0005266_abnormal_metabolism0.63023713
128MP0002971_abnormal_brown_adipose0.62573353
129MP0005508_abnormal_skeleton_morphology0.62502536
130MP0010771_integument_phenotype0.61766163
131MP0003077_abnormal_cell_cycle0.61556316

Predicted human phenotypes

RankGene SetZ-score
1Hyporeflexia of lower limbs (HP:0002600)6.03393653
2Exercise-induced muscle cramps (HP:0003710)5.68507681
3Muscle fiber splitting (HP:0003555)5.23382302
4Increased connective tissue (HP:0009025)5.02368479
5Right ventricular cardiomyopathy (HP:0011663)4.98479469
6Ventricular tachycardia (HP:0004756)4.72001380
7Sudden death (HP:0001699)4.52139025
8Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.51964671
9Muscle fiber inclusion bodies (HP:0100299)4.46705493
10Exercise-induced myalgia (HP:0003738)4.33660127
11Follicular hyperkeratosis (HP:0007502)4.05177010
12Difficulty running (HP:0009046)4.02329638
13Type 1 muscle fiber predominance (HP:0003803)4.00683300
14Nemaline bodies (HP:0003798)3.98406311
15Calf muscle hypertrophy (HP:0008981)3.97589065
16Myoglobinuria (HP:0002913)3.88736561
17Distal lower limb muscle weakness (HP:0009053)3.79067885
18Difficulty climbing stairs (HP:0003551)3.77275424
19Muscle hypertrophy of the lower extremities (HP:0008968)3.75736532
20Premature rupture of membranes (HP:0001788)3.73651847
21Rhabdomyolysis (HP:0003201)3.48898164
22Abnormality of the calf musculature (HP:0001430)3.39597800
23EMG: myopathic abnormalities (HP:0003458)3.35121200
24Lipoatrophy (HP:0100578)3.29820433
25Distal arthrogryposis (HP:0005684)3.15811244
26Subaortic stenosis (HP:0001682)3.13769602
27Abnormality of the left ventricular outflow tract (HP:0011103)3.13769602
28Vascular tortuosity (HP:0004948)3.10974993
29Protrusio acetabuli (HP:0003179)3.07916865
30Areflexia of lower limbs (HP:0002522)2.98213726
31Hypoplastic ischia (HP:0003175)2.98192374
32Ulnar deviation of the wrist (HP:0003049)2.92326517
33Atrial fibrillation (HP:0005110)2.91768778
34Distal lower limb amyotrophy (HP:0008944)2.90036984
35Muscle stiffness (HP:0003552)2.87292200
36Bundle branch block (HP:0011710)2.83994118
37Arterial tortuosity (HP:0005116)2.80433212
38Abnormality of skeletal muscle fiber size (HP:0012084)2.74557541
39Dilated cardiomyopathy (HP:0001644)2.74468114
40Spinal rigidity (HP:0003306)2.68500669
41Soft skin (HP:0000977)2.63951071
42Primary atrial arrhythmia (HP:0001692)2.60822132
43Wormian bones (HP:0002645)2.59819545
44Abnormality of the ischium (HP:0003174)2.59523884
45Reduced subcutaneous adipose tissue (HP:0003758)2.58907668
46Increased variability in muscle fiber diameter (HP:0003557)2.58695702
47Osteolytic defects of the phalanges of the hand (HP:0009771)2.56777202
48Osteolytic defects of the hand bones (HP:0009699)2.56777202
49Ankyloglossia (HP:0010296)2.50217998
50Vertebral compression fractures (HP:0002953)2.47446725
51Abnormality of the calcaneus (HP:0008364)2.46981595
52Spondylolisthesis (HP:0003302)2.46970844
53Supraventricular tachycardia (HP:0004755)2.44604216
54Supraventricular arrhythmia (HP:0005115)2.44448824
55Facial diplegia (HP:0001349)2.43419883
56Round ear (HP:0100830)2.42893921
57Ankle contracture (HP:0006466)2.40847141
58Dilatation of the ascending aorta (HP:0005111)2.40146373
59Bladder diverticulum (HP:0000015)2.39341790
60Overgrowth (HP:0001548)2.39189754
61Cardiovascular calcification (HP:0011915)2.36265285
62Alopecia of scalp (HP:0002293)2.34635007
63Scapular winging (HP:0003691)2.33470408
64Cervical subluxation (HP:0003308)2.32954196
65Foot dorsiflexor weakness (HP:0009027)2.32704741
66Frequent falls (HP:0002359)2.32593621
67Syringomyelia (HP:0003396)2.32513654
68Spinal cord lesions (HP:0100561)2.32513654
69Natal tooth (HP:0000695)2.31942858
70Ventricular arrhythmia (HP:0004308)2.30627468
71Myotonia (HP:0002486)2.30111588
72Abnormal atrioventricular conduction (HP:0005150)2.29892044
73Asymmetric septal hypertrophy (HP:0001670)2.28358821
74Abnormality of oral frenula (HP:0000190)2.28220181
75Mildly elevated creatine phosphokinase (HP:0008180)2.27957694
76Absent phalangeal crease (HP:0006109)2.24478104
77Elbow flexion contracture (HP:0002987)2.22108126
78Palpitations (HP:0001962)2.21722195
79Abnormality of nail color (HP:0100643)2.21109614
80Cerebral aneurysm (HP:0004944)2.20555259
81Abnormality of the foot musculature (HP:0001436)2.18999504
82Limb-girdle muscle atrophy (HP:0003797)2.18618656
83Neck muscle weakness (HP:0000467)2.16254622
84Onycholysis (HP:0001806)2.14948204
85Short middle phalanx of the 5th finger (HP:0004220)2.14015169
86Calcaneovalgus deformity (HP:0001848)2.13851980
87Metaphyseal cupping (HP:0003021)2.12804745
88Microglossia (HP:0000171)2.12531125
89Generalized amyotrophy (HP:0003700)2.12011293
90Atrophic scars (HP:0001075)2.11172336
91Myopathic facies (HP:0002058)2.10381166
92Heart block (HP:0012722)2.09927704
93Mitral stenosis (HP:0001718)2.09329576
94Chromsome breakage (HP:0040012)2.09265370
95Entropion (HP:0000621)2.08622437
96Relative macrocephaly (HP:0004482)2.08045018
97EMG: neuropathic changes (HP:0003445)2.04969460
98Lower limb amyotrophy (HP:0007210)2.02795879
99Glucose intolerance (HP:0000833)2.02572824
100Delayed closure of the anterior fontanelle (HP:0001476)1.99808382
101Deformed tarsal bones (HP:0008119)1.99250984
102Generalized muscle weakness (HP:0003324)1.99182161
103Fragile skin (HP:0001030)1.99049234
104Proximal amyotrophy (HP:0007126)1.96941079
105Deep philtrum (HP:0002002)1.94687378
106Syncope (HP:0001279)1.94403902
107Chromosomal breakage induced by crosslinking agents (HP:0003221)1.94078798
108Thick nail (HP:0001805)1.93878806
109Ventricular fibrillation (HP:0001663)1.91785631
110Abnormality of the umbilical cord (HP:0010881)1.91594643
111Hip contracture (HP:0003273)1.90405088
112Abnormal finger flexion creases (HP:0006143)1.88684670
113Tetraparesis (HP:0002273)1.88244277
114Mitral valve prolapse (HP:0001634)1.87906596
115Atrioventricular block (HP:0001678)1.87757867
116Short nail (HP:0001799)1.87462123
117Muscular dystrophy (HP:0003560)1.87412155
118Abnormality of the acetabulum (HP:0003170)1.86412078
119Curly hair (HP:0002212)1.85621891
120Blue sclerae (HP:0000592)1.83146512
121Gowers sign (HP:0003391)1.82132005
122Cupped ribs (HP:0000887)1.81880005
123Rectal prolapse (HP:0002035)1.81507526
124Conjunctival hamartoma (HP:0100780)1.81445014
125Malignant hyperthermia (HP:0002047)1.79348386
126Peritonitis (HP:0002586)1.78334276
127Abnormality of the distal phalanges of the toes (HP:0010182)1.78275245
128Vascular calcification (HP:0004934)1.78037090
129Abnormal delivery (HP:0001787)1.77074477
130Palmoplantar keratoderma (HP:0000982)1.76600149
131Myocardial infarction (HP:0001658)1.75364329
132Achilles tendon contracture (HP:0001771)1.75288137
133Aortic regurgitation (HP:0001659)1.75025651
134Breech presentation (HP:0001623)1.74221864
135Selective tooth agenesis (HP:0001592)1.74124577
136Aortic dissection (HP:0002647)1.72848382
137Neonatal short-limb short stature (HP:0008921)1.72537743
138Joint laxity (HP:0001388)1.71071120
139Wrist flexion contracture (HP:0001239)1.70661788
140Milia (HP:0001056)1.70205279
141Progressive muscle weakness (HP:0003323)1.70042807
142Delayed cranial suture closure (HP:0000270)1.69594840
143Ureteral duplication (HP:0000073)1.68755648
144Limb-girdle muscle weakness (HP:0003325)1.66845149
145Cubitus valgus (HP:0002967)1.66207575
146Aneurysm (HP:0002617)1.66052600
147Genu recurvatum (HP:0002816)1.65944783
148Aortic aneurysm (HP:0004942)1.65706310
149Slender build (HP:0001533)1.65692567
150Knee flexion contracture (HP:0006380)1.63617647
151Acute myeloid leukemia (HP:0004808)1.63415922
152Mesomelia (HP:0003027)1.63315583
153Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.62725108
154Biconcave vertebral bodies (HP:0004586)1.61863378
155Toxemia of pregnancy (HP:0100603)1.61818886
156Neoplasm of the rectum (HP:0100743)1.60943400
157Abnormality of the intrinsic pathway (HP:0010989)1.60482421
158Vertebral arch anomaly (HP:0008438)1.60440803
159Abnormality of the tricuspid valve (HP:0001702)1.59759010
160Plantar hyperkeratosis (HP:0007556)1.59130705

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.81994458
2PDK33.43265565
3PDK43.43265565
4TRIB32.90243922
5PDK22.47965188
6OBSCN2.41255017
7MAP3K32.30338321
8PKN22.29914311
9BUB12.22732246
10NEK12.15185879
11TRPM72.12165923
12EIF2AK32.08130038
13MET2.00735533
14MAPKAPK32.00534965
15NEK91.95647999
16PBK1.84549961
17PHKG21.81673365
18PHKG11.81673365
19LATS11.80495335
20NEK21.69599821
21AKT31.66966171
22WNK11.59358806
23DMPK1.53501176
24LMTK21.52041430
25STK31.50972491
26CDK121.50177543
27PIK3CG1.47901598
28LRRK21.46154279
29RPS6KA41.43751830
30STK101.35539029
31MAP3K121.34467207
32IRAK31.33322150
33MAP2K31.31554888
34STK241.29557485
35SCYL21.29149799
36BMPR21.27829080
37TGFBR21.26318653
38STK38L1.24750143
39EIF2AK11.24638292
40PTK61.20112327
41STK41.19012819
42EEF2K1.18729578
43ERBB41.15604931
44FLT31.11935839
45RPS6KB21.11260994
46LATS21.10129068
47MOS1.09659525
48PIK3CA1.08842645
49BRSK21.07084529
50NME21.06264188
51PDGFRA1.00647542
52TTK1.00039713
53DDR20.95522275
54PLK30.92764134
55TESK10.92501006
56ZAK0.91495292
57PLK40.91438334
58BRD40.91375626
59RIPK10.90110187
60MAP3K100.88774900
61WNK40.87081744
62FRK0.85971035
63CLK10.83753838
64BRAF0.82807635
65CDK60.82719778
66MARK30.81092387
67EIF2AK20.80944043
68MAP3K60.78998479
69MAP3K110.76945387
70ILK0.76221812
71TAF10.75341477
72FER0.73517228
73CDK40.73296678
74MELK0.71270642
75CHEK20.70782021
76CDK80.70238449
77JAK30.68936101
78BRSK10.68746151
79LIMK10.68686993
80MTOR0.68610648
81AURKB0.68420869
82MYLK0.66221161
83MAP3K80.66193204
84JAK10.64116172
85EPHA20.63328872
86MAP3K130.61253429
87CDK90.60411362
88MAP3K140.58452448
89CDK70.57953604
90MAP3K50.57913185
91MKNK20.57341525
92ERN10.57258112
93STK160.55436943
94FGFR10.54695895
95CDC70.54584433
96PAK30.53506778
97PRKD10.52874021
98NLK0.51828048
99KSR20.50641312
100MAP3K20.50428834
101PTK2B0.49876511
102PRKAA20.49723009
103PTK20.49112609
104RAF10.48859698
105TBK10.48546898
106CCNB10.47363888
107CHEK10.47103170
108PIM20.46489466
109PRKG20.45482496
110BCR0.45279739
111ICK0.44916560
112MKNK10.44756207
113WEE10.44747188
114KSR10.44618390
115PRKAA10.44500336
116MAPKAPK20.44062673
117MST1R0.43250395
118SRPK10.43047132
119PLK10.42918336
120PAK20.42723455
121ALK0.41128848
122STK380.41091985
123ROCK10.40934298
124PINK10.40657566
125PIM10.39744735
126MST40.37936613
127BMX0.37592285
128EPHB20.37035838
129PDGFRB0.36931521
130AKT20.35816231
131PAK40.34257518
132EPHB10.34218656
133STK390.33158812
134RPS6KC10.33115831
135RPS6KL10.33115831
136FGFR30.33012059
137ERBB30.32364282
138MAP3K70.31757852
139RET0.30520357
140DYRK30.29896797

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.56010409
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.86586198
3Dilated cardiomyopathy_Homo sapiens_hsa054142.53044016
4Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.35111499
5Propanoate metabolism_Homo sapiens_hsa006401.96982084
6ECM-receptor interaction_Homo sapiens_hsa045121.94695514
7Viral myocarditis_Homo sapiens_hsa054161.89827193
8Cardiac muscle contraction_Homo sapiens_hsa042601.89250549
92-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.85708841
10Sulfur metabolism_Homo sapiens_hsa009201.78761577
11Focal adhesion_Homo sapiens_hsa045101.78020966
12Adherens junction_Homo sapiens_hsa045201.77161371
13Carbon metabolism_Homo sapiens_hsa012001.74066873
14Nucleotide excision repair_Homo sapiens_hsa034201.71251035
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.68234456
16Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.62410014
17Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.59374072
18Circadian rhythm_Homo sapiens_hsa047101.58584451
19Small cell lung cancer_Homo sapiens_hsa052221.58192439
20DNA replication_Homo sapiens_hsa030301.57151360
21Amoebiasis_Homo sapiens_hsa051461.56645783
22Insulin resistance_Homo sapiens_hsa049311.54727155
23Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.54448565
24Proteoglycans in cancer_Homo sapiens_hsa052051.47528543
25Fatty acid degradation_Homo sapiens_hsa000711.45321947
26Leukocyte transendothelial migration_Homo sapiens_hsa046701.41644567
27Insulin signaling pathway_Homo sapiens_hsa049101.30605824
28Legionellosis_Homo sapiens_hsa051341.29551466
29p53 signaling pathway_Homo sapiens_hsa041151.28007232
30Adipocytokine signaling pathway_Homo sapiens_hsa049201.27821490
31Dorso-ventral axis formation_Homo sapiens_hsa043201.22968550
32One carbon pool by folate_Homo sapiens_hsa006701.22636508
33Glucagon signaling pathway_Homo sapiens_hsa049221.20250436
34Pyruvate metabolism_Homo sapiens_hsa006201.18821687
35Tight junction_Homo sapiens_hsa045301.17845433
36Chronic myeloid leukemia_Homo sapiens_hsa052201.16494337
37Central carbon metabolism in cancer_Homo sapiens_hsa052301.15265030
38Toxoplasmosis_Homo sapiens_hsa051451.15095303
39Non-homologous end-joining_Homo sapiens_hsa034501.11965032
40HIF-1 signaling pathway_Homo sapiens_hsa040661.11633515
41Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.10471120
42TGF-beta signaling pathway_Homo sapiens_hsa043501.09717852
43Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.08913719
44mTOR signaling pathway_Homo sapiens_hsa041501.08009235
45Mismatch repair_Homo sapiens_hsa034301.06485408
46Starch and sucrose metabolism_Homo sapiens_hsa005001.05274207
47Basal transcription factors_Homo sapiens_hsa030221.05150681
48Cell cycle_Homo sapiens_hsa041101.04947818
49MicroRNAs in cancer_Homo sapiens_hsa052061.03967823
50AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.03668660
51AMPK signaling pathway_Homo sapiens_hsa041521.02154741
52Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.98044220
53Protein export_Homo sapiens_hsa030600.97899488
54Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.97181327
55Antigen processing and presentation_Homo sapiens_hsa046120.96850479
56Graft-versus-host disease_Homo sapiens_hsa053320.91015379
57Regulation of actin cytoskeleton_Homo sapiens_hsa048100.90496029
58Fatty acid metabolism_Homo sapiens_hsa012120.90157904
59Non-small cell lung cancer_Homo sapiens_hsa052230.88839474
60Thyroid cancer_Homo sapiens_hsa052160.88300169
61Apoptosis_Homo sapiens_hsa042100.88125572
62Salmonella infection_Homo sapiens_hsa051320.83449474
63FoxO signaling pathway_Homo sapiens_hsa040680.83332295
64Leishmaniasis_Homo sapiens_hsa051400.79451358
65Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.79435822
66Proteasome_Homo sapiens_hsa030500.78655169
67Platelet activation_Homo sapiens_hsa046110.77557017
68Acute myeloid leukemia_Homo sapiens_hsa052210.76883867
69Pancreatic cancer_Homo sapiens_hsa052120.76712119
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.76412990
71Hippo signaling pathway_Homo sapiens_hsa043900.75533706
72Fanconi anemia pathway_Homo sapiens_hsa034600.75222327
73RNA degradation_Homo sapiens_hsa030180.74016787
74Sphingolipid metabolism_Homo sapiens_hsa006000.73902550
75mRNA surveillance pathway_Homo sapiens_hsa030150.73449248
76Bladder cancer_Homo sapiens_hsa052190.73348500
77Hepatitis B_Homo sapiens_hsa051610.73324130
78VEGF signaling pathway_Homo sapiens_hsa043700.72215012
79Viral carcinogenesis_Homo sapiens_hsa052030.71675303
80N-Glycan biosynthesis_Homo sapiens_hsa005100.71251538
81Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.69990794
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69472030
83Lysine degradation_Homo sapiens_hsa003100.68686741
84Mineral absorption_Homo sapiens_hsa049780.68492245
85Prostate cancer_Homo sapiens_hsa052150.67572544
86Osteoclast differentiation_Homo sapiens_hsa043800.67320007
87Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.67137319
88RNA transport_Homo sapiens_hsa030130.66064979
89Pentose phosphate pathway_Homo sapiens_hsa000300.65476805
90TNF signaling pathway_Homo sapiens_hsa046680.64921989
91Malaria_Homo sapiens_hsa051440.64880641
92Glioma_Homo sapiens_hsa052140.63693665
93PPAR signaling pathway_Homo sapiens_hsa033200.63421947
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.63192591
95Glutathione metabolism_Homo sapiens_hsa004800.63105316
96Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.62875260
97HTLV-I infection_Homo sapiens_hsa051660.62515915
98Endometrial cancer_Homo sapiens_hsa052130.62359326
99Biosynthesis of amino acids_Homo sapiens_hsa012300.62034735
100PI3K-Akt signaling pathway_Homo sapiens_hsa041510.60716453
101Pyrimidine metabolism_Homo sapiens_hsa002400.60332840
102Oocyte meiosis_Homo sapiens_hsa041140.60170460
103Folate biosynthesis_Homo sapiens_hsa007900.59605610
104NOD-like receptor signaling pathway_Homo sapiens_hsa046210.58934176
105Parkinsons disease_Homo sapiens_hsa050120.57765338
106Shigellosis_Homo sapiens_hsa051310.57539115
107Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57145600
108Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55594592
109Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.55094172
110Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.54820204
111Renal cell carcinoma_Homo sapiens_hsa052110.54220146
112Renin-angiotensin system_Homo sapiens_hsa046140.53041127
113Fatty acid biosynthesis_Homo sapiens_hsa000610.52796579
114Selenocompound metabolism_Homo sapiens_hsa004500.52677093
115Melanoma_Homo sapiens_hsa052180.50295857
116Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.49883371
117Tuberculosis_Homo sapiens_hsa051520.49538757
118Fructose and mannose metabolism_Homo sapiens_hsa000510.47641869
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47482524
120Protein digestion and absorption_Homo sapiens_hsa049740.47440118
121Homologous recombination_Homo sapiens_hsa034400.46943755
122Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46123055
123Hepatitis C_Homo sapiens_hsa051600.45883624
124RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45415291
125Epstein-Barr virus infection_Homo sapiens_hsa051690.43551125
126Galactose metabolism_Homo sapiens_hsa000520.42329635
127Inositol phosphate metabolism_Homo sapiens_hsa005620.42038602
128Arginine and proline metabolism_Homo sapiens_hsa003300.41880743
129Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.41623000
130Phagosome_Homo sapiens_hsa041450.41442549
131Pathways in cancer_Homo sapiens_hsa052000.41412984
132Hematopoietic cell lineage_Homo sapiens_hsa046400.41189147
133Neurotrophin signaling pathway_Homo sapiens_hsa047220.40740648
134SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37794304

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