

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of RIG-I signaling pathway (GO:0039535) | 5.76242882 |
| 2 | regulation of necroptotic process (GO:0060544) | 5.71642465 |
| 3 | regulation of female gonad development (GO:2000194) | 5.66504620 |
| 4 | regulation of protein polyubiquitination (GO:1902914) | 5.55734480 |
| 5 | NIK/NF-kappaB signaling (GO:0038061) | 5.39073088 |
| 6 | necroptotic process (GO:0070266) | 4.92614934 |
| 7 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 4.83117802 |
| 8 | regulation of hypersensitivity (GO:0002883) | 4.75504291 |
| 9 | interkinetic nuclear migration (GO:0022027) | 4.66667227 |
| 10 | negative regulation of necroptotic process (GO:0060546) | 4.62092697 |
| 11 | programmed necrotic cell death (GO:0097300) | 4.40633235 |
| 12 | necrotic cell death (GO:0070265) | 4.30736024 |
| 13 | negative regulation of peptidyl-serine phosphorylation (GO:0033137) | 4.26012585 |
| 14 | positive regulation of granulocyte differentiation (GO:0030854) | 4.16963840 |
| 15 | centriole replication (GO:0007099) | 4.09608673 |
| 16 | phagocytosis, engulfment (GO:0006911) | 4.09024627 |
| 17 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.01046982 |
| 18 | regulation of necrotic cell death (GO:0010939) | 3.96079607 |
| 19 | fat-soluble vitamin biosynthetic process (GO:0042362) | 3.89398378 |
| 20 | negative regulation of interleukin-17 production (GO:0032700) | 3.88336283 |
| 21 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.83603616 |
| 22 | neutrophil activation involved in immune response (GO:0002283) | 3.83564209 |
| 23 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.83231749 |
| 24 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 3.77459808 |
| 25 | negative regulation of necrotic cell death (GO:0060547) | 3.74550219 |
| 26 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.70004629 |
| 27 | chemokine-mediated signaling pathway (GO:0070098) | 3.68361658 |
| 28 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.67336122 |
| 29 | positive regulation of mast cell degranulation (GO:0043306) | 3.61250881 |
| 30 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.61250881 |
| 31 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.60951664 |
| 32 | proteasome assembly (GO:0043248) | 3.56799071 |
| 33 | positive regulation of mast cell activation (GO:0033005) | 3.56178701 |
| 34 | regulation of interleukin-17 production (GO:0032660) | 3.52268995 |
| 35 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.47910935 |
| 36 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.47910935 |
| 37 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.47679765 |
| 38 | protein localization to Golgi apparatus (GO:0034067) | 3.45263325 |
| 39 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.43018979 |
| 40 | regulation of mast cell activation (GO:0033003) | 3.35086662 |
| 41 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.33442169 |
| 42 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.27649046 |
| 43 | mast cell activation (GO:0045576) | 3.24861140 |
| 44 | mature B cell differentiation involved in immune response (GO:0002313) | 3.21109303 |
| 45 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 3.20672301 |
| 46 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.18988948 |
| 47 | positive regulation of B cell mediated immunity (GO:0002714) | 3.18988948 |
| 48 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.18939780 |
| 49 | immunoglobulin mediated immune response (GO:0016064) | 3.18869160 |
| 50 | ribosomal small subunit assembly (GO:0000028) | 3.18602479 |
| 51 | I-kappaB phosphorylation (GO:0007252) | 3.18282949 |
| 52 | positive regulation of isotype switching (GO:0045830) | 3.17820602 |
| 53 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.16264585 |
| 54 | detection of other organism (GO:0098543) | 3.14762277 |
| 55 | microglial cell activation (GO:0001774) | 3.13389724 |
| 56 | regulation of mast cell degranulation (GO:0043304) | 3.13091738 |
| 57 | protein localization to peroxisome (GO:0072662) | 3.12812866 |
| 58 | protein targeting to peroxisome (GO:0006625) | 3.12812866 |
| 59 | establishment of protein localization to peroxisome (GO:0072663) | 3.12812866 |
| 60 | detection of bacterium (GO:0016045) | 3.10355577 |
| 61 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.09326976 |
| 62 | peroxisome fission (GO:0016559) | 3.08504475 |
| 63 | response to pheromone (GO:0019236) | 3.06284555 |
| 64 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.03834111 |
| 65 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.02089418 |
| 66 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 3.00878646 |
| 67 | adenosine metabolic process (GO:0046085) | 3.00045569 |
| 68 | detection of molecule of bacterial origin (GO:0032490) | 2.99469660 |
| 69 | purine nucleotide salvage (GO:0032261) | 2.98775118 |
| 70 | response to xenobiotic stimulus (GO:0009410) | 2.98566897 |
| 71 | membrane invagination (GO:0010324) | 2.98555224 |
| 72 | purine-containing compound salvage (GO:0043101) | 2.96227185 |
| 73 | detection of external biotic stimulus (GO:0098581) | 2.94930628 |
| 74 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.94401714 |
| 75 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.92244190 |
| 76 | positive regulation of interleukin-17 production (GO:0032740) | 2.84001180 |
| 77 | B cell mediated immunity (GO:0019724) | 2.83673221 |
| 78 | hepatocyte apoptotic process (GO:0097284) | 2.82731261 |
| 79 | positive regulation of DNA recombination (GO:0045911) | 2.82330490 |
| 80 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.81589595 |
| 81 | mast cell activation involved in immune response (GO:0002279) | 2.78234511 |
| 82 | mast cell degranulation (GO:0043303) | 2.78234511 |
| 83 | parental behavior (GO:0060746) | 2.77509763 |
| 84 | peroxisomal transport (GO:0043574) | 2.77437500 |
| 85 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 2.76646712 |
| 86 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.75216352 |
| 87 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.75216352 |
| 88 | positive regulation of T cell cytokine production (GO:0002726) | 2.74435382 |
| 89 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.73520235 |
| 90 | Peyers patch development (GO:0048541) | 2.73520235 |
| 91 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 2.71261187 |
| 92 | negative regulation of mast cell activation (GO:0033004) | 2.70298156 |
| 93 | positive regulation of interleukin-1 beta production (GO:0032731) | 2.69888747 |
| 94 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.68970053 |
| 95 | hepatocyte differentiation (GO:0070365) | 2.66216924 |
| 96 | mature B cell differentiation (GO:0002335) | 2.63744202 |
| 97 | monoamine transport (GO:0015844) | 2.62604850 |
| 98 | intracellular protein transmembrane import (GO:0044743) | 2.62162204 |
| 99 | regulation of immunoglobulin mediated immune response (GO:0002889) | 2.61487997 |
| 100 | regulation of B cell mediated immunity (GO:0002712) | 2.60102651 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 5.38001143 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.37016243 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.74529183 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.59533651 |
| 5 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.26193157 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.12818655 |
| 7 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.06787962 |
| 8 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.57989793 |
| 9 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.52937369 |
| 10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.49830972 |
| 11 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.48756254 |
| 12 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.30271053 |
| 13 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.24056559 |
| 14 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.18673850 |
| 15 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.03384361 |
| 16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.98525165 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.97993019 |
| 18 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.97414733 |
| 19 | MYB_26560356_Chip-Seq_TH2_Human | 1.93236675 |
| 20 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.88643920 |
| 21 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.80328367 |
| 22 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.74924469 |
| 23 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.74512180 |
| 24 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.72294991 |
| 25 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.71065744 |
| 26 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.70441445 |
| 27 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.68685802 |
| 28 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.63745786 |
| 29 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.62415582 |
| 30 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.60249560 |
| 31 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.59135428 |
| 32 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.57439831 |
| 33 | SPI1_23127762_ChIP-Seq_K562_Human | 1.56826040 |
| 34 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.55765628 |
| 35 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.55534556 |
| 36 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.54368082 |
| 37 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.52563906 |
| 38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.51540793 |
| 39 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.47836863 |
| 40 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.44053702 |
| 41 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.42437878 |
| 42 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.40754538 |
| 43 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.36870529 |
| 44 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.35833292 |
| 45 | GATA3_26560356_Chip-Seq_TH2_Human | 1.34199069 |
| 46 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.33772049 |
| 47 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.33106231 |
| 48 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.32663800 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.29788642 |
| 50 | GATA3_26560356_Chip-Seq_TH1_Human | 1.29401296 |
| 51 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.28645735 |
| 52 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.24685520 |
| 53 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.22369478 |
| 54 | AR_25329375_ChIP-Seq_VCAP_Human | 1.21979553 |
| 55 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.21296411 |
| 56 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.21013741 |
| 57 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.20376132 |
| 58 | MYB_26560356_Chip-Seq_TH1_Human | 1.19804589 |
| 59 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.17641334 |
| 60 | GATA1_22025678_ChIP-Seq_K562_Human | 1.17525813 |
| 61 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17324927 |
| 62 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.16913522 |
| 63 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.16834659 |
| 64 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.16642022 |
| 65 | VDR_22108803_ChIP-Seq_LS180_Human | 1.14661162 |
| 66 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.14567901 |
| 67 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.13339392 |
| 68 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.12410935 |
| 69 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.10762480 |
| 70 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.08730652 |
| 71 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.08697843 |
| 72 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.07430630 |
| 73 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.07282366 |
| 74 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.06051629 |
| 75 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.05244734 |
| 76 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03572715 |
| 77 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02327591 |
| 78 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.01443542 |
| 79 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99977603 |
| 80 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.99833194 |
| 81 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98321807 |
| 82 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.98186273 |
| 83 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.96318431 |
| 84 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.94297968 |
| 85 | GATA1_19941826_ChIP-Seq_K562_Human | 0.93445280 |
| 86 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.92156970 |
| 87 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.91096456 |
| 88 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.90564481 |
| 89 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90266444 |
| 90 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.90133640 |
| 91 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.89154582 |
| 92 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.89068447 |
| 93 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.88946776 |
| 94 | AR_20517297_ChIP-Seq_VCAP_Human | 0.88786993 |
| 95 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.88785092 |
| 96 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.88622694 |
| 97 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.88527033 |
| 98 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88210212 |
| 99 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.87812751 |
| 100 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.87648307 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.53990861 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.85469066 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.62221619 |
| 4 | MP0003806_abnormal_nucleotide_metabolis | 3.28401148 |
| 5 | MP0003724_increased_susceptibility_to | 3.09938649 |
| 6 | MP0004147_increased_porphyrin_level | 2.60233190 |
| 7 | MP0003787_abnormal_imprinting | 2.28899642 |
| 8 | MP0009785_altered_susceptibility_to | 2.28284361 |
| 9 | MP0010155_abnormal_intestine_physiology | 2.24710468 |
| 10 | MP0005075_abnormal_melanosome_morpholog | 2.21938189 |
| 11 | MP0001188_hyperpigmentation | 2.21901590 |
| 12 | MP0001545_abnormal_hematopoietic_system | 2.19717292 |
| 13 | MP0005397_hematopoietic_system_phenotyp | 2.19717292 |
| 14 | MP0008260_abnormal_autophagy | 2.09805018 |
| 15 | MP0003646_muscle_fatigue | 2.00912313 |
| 16 | MP0002396_abnormal_hematopoietic_system | 2.00430322 |
| 17 | MP0009697_abnormal_copulation | 1.98651228 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.92204383 |
| 19 | MP0005671_abnormal_response_to | 1.92180187 |
| 20 | MP0003866_abnormal_defecation | 1.91913115 |
| 21 | MP0002148_abnormal_hypersensitivity_rea | 1.87493959 |
| 22 | MP0001800_abnormal_humoral_immune | 1.83637078 |
| 23 | MP0001764_abnormal_homeostasis | 1.75695436 |
| 24 | MP0002419_abnormal_innate_immunity | 1.74206471 |
| 25 | MP0005025_abnormal_response_to | 1.70482769 |
| 26 | MP0002723_abnormal_immune_serum | 1.66392149 |
| 27 | MP0009764_decreased_sensitivity_to | 1.62937088 |
| 28 | MP0002420_abnormal_adaptive_immunity | 1.62607701 |
| 29 | MP0002452_abnormal_antigen_presenting | 1.59912655 |
| 30 | MP0002398_abnormal_bone_marrow | 1.59438359 |
| 31 | MP0003183_abnormal_peptide_metabolism | 1.59051378 |
| 32 | MP0001819_abnormal_immune_cell | 1.58648762 |
| 33 | MP0005410_abnormal_fertilization | 1.57299406 |
| 34 | MP0008057_abnormal_DNA_replication | 1.52856242 |
| 35 | MP0005000_abnormal_immune_tolerance | 1.44496737 |
| 36 | MP0001790_abnormal_immune_system | 1.44225597 |
| 37 | MP0005387_immune_system_phenotype | 1.44225597 |
| 38 | MP0005464_abnormal_platelet_physiology | 1.43106229 |
| 39 | MP0000716_abnormal_immune_system | 1.42030165 |
| 40 | MP0005084_abnormal_gallbladder_morpholo | 1.41719845 |
| 41 | MP0002166_altered_tumor_susceptibility | 1.39852920 |
| 42 | MP0002722_abnormal_immune_system | 1.39761850 |
| 43 | MP0004883_abnormal_blood_vessel | 1.38305647 |
| 44 | MP0003436_decreased_susceptibility_to | 1.37055426 |
| 45 | MP0000703_abnormal_thymus_morphology | 1.36579194 |
| 46 | MP0005174_abnormal_tail_pigmentation | 1.35248309 |
| 47 | MP0000689_abnormal_spleen_morphology | 1.34884736 |
| 48 | MP0006036_abnormal_mitochondrial_physio | 1.34854896 |
| 49 | MP0003656_abnormal_erythrocyte_physiolo | 1.31857476 |
| 50 | MP0004142_abnormal_muscle_tone | 1.30239158 |
| 51 | MP0004130_abnormal_muscle_cell | 1.29901719 |
| 52 | MP0003448_altered_tumor_morphology | 1.29246241 |
| 53 | MP0002132_abnormal_respiratory_system | 1.26243666 |
| 54 | MP0000685_abnormal_immune_system | 1.25536050 |
| 55 | MP0000858_altered_metastatic_potential | 1.24109211 |
| 56 | MP0003763_abnormal_thymus_physiology | 1.23525157 |
| 57 | MP0005376_homeostasis/metabolism_phenot | 1.21773348 |
| 58 | MP0005266_abnormal_metabolism | 1.20900154 |
| 59 | MP0003878_abnormal_ear_physiology | 1.20796598 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 1.20796598 |
| 61 | MP0001845_abnormal_inflammatory_respons | 1.20617070 |
| 62 | MP0002429_abnormal_blood_cell | 1.18961676 |
| 63 | MP0002837_dystrophic_cardiac_calcinosis | 1.17703182 |
| 64 | MP0000465_gastrointestinal_hemorrhage | 1.14323028 |
| 65 | MP0009333_abnormal_splenocyte_physiolog | 1.13298266 |
| 66 | MP0000681_abnormal_thyroid_gland | 1.09563587 |
| 67 | MP0001986_abnormal_taste_sensitivity | 1.08230247 |
| 68 | MP0003172_abnormal_lysosome_physiology | 1.07804756 |
| 69 | MP0002006_tumorigenesis | 1.06122121 |
| 70 | MP0001191_abnormal_skin_condition | 1.05010531 |
| 71 | MP0005360_urolithiasis | 1.04606471 |
| 72 | MP0004084_abnormal_cardiac_muscle | 1.01878667 |
| 73 | MP0006082_CNS_inflammation | 0.99099829 |
| 74 | MP0001177_atelectasis | 0.98391291 |
| 75 | MP0005164_abnormal_response_to | 0.96079150 |
| 76 | MP0004381_abnormal_hair_follicle | 0.94396943 |
| 77 | MP0002876_abnormal_thyroid_physiology | 0.93786914 |
| 78 | MP0002332_abnormal_exercise_endurance | 0.93448541 |
| 79 | MP0004145_abnormal_muscle_electrophysio | 0.92076643 |
| 80 | MP0005166_decreased_susceptibility_to | 0.91949944 |
| 81 | MP0001664_abnormal_digestion | 0.91001082 |
| 82 | MP0008469_abnormal_protein_level | 0.90919304 |
| 83 | MP0004043_abnormal_pH_regulation | 0.89166822 |
| 84 | MP0000249_abnormal_blood_vessel | 0.88787798 |
| 85 | MP0005535_abnormal_body_temperature | 0.86252248 |
| 86 | MP0004808_abnormal_hematopoietic_stem | 0.84645542 |
| 87 | MP0002405_respiratory_system_inflammati | 0.84205847 |
| 88 | MP0000516_abnormal_urinary_system | 0.82103038 |
| 89 | MP0005367_renal/urinary_system_phenotyp | 0.82103038 |
| 90 | MP0009278_abnormal_bone_marrow | 0.81640446 |
| 91 | MP0002019_abnormal_tumor_incidence | 0.80970739 |
| 92 | MP0005645_abnormal_hypothalamus_physiol | 0.80468667 |
| 93 | MP0002127_abnormal_cardiovascular_syste | 0.76077326 |
| 94 | MP0003300_gastrointestinal_ulcer | 0.75188474 |
| 95 | MP0009763_increased_sensitivity_to | 0.73756690 |
| 96 | MP0001853_heart_inflammation | 0.69860066 |
| 97 | MP0004036_abnormal_muscle_relaxation | 0.68808736 |
| 98 | MP0001756_abnormal_urination | 0.66197781 |
| 99 | MP0005448_abnormal_energy_balance | 0.64484193 |
| 100 | MP0002234_abnormal_pharynx_morphology | 0.63720184 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 4.15078487 |
| 2 | Metaphyseal dysplasia (HP:0100255) | 4.14335776 |
| 3 | Enlarged epiphyses (HP:0010580) | 4.01648033 |
| 4 | Thrombocytosis (HP:0001894) | 3.94496625 |
| 5 | Papilledema (HP:0001085) | 3.89876243 |
| 6 | Limb hypertonia (HP:0002509) | 3.57964191 |
| 7 | Brushfield spots (HP:0001088) | 3.39127978 |
| 8 | Neonatal respiratory distress (HP:0002643) | 3.38733897 |
| 9 | Partial agenesis of the corpus callosum (HP:0001338) | 3.34094663 |
| 10 | Global brain atrophy (HP:0002283) | 3.33602257 |
| 11 | Progressive microcephaly (HP:0000253) | 3.30851436 |
| 12 | Short tibia (HP:0005736) | 3.27258226 |
| 13 | Autoimmune hemolytic anemia (HP:0001890) | 3.19081720 |
| 14 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 3.12230728 |
| 15 | Acute hepatic failure (HP:0006554) | 3.06441989 |
| 16 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 3.05548012 |
| 17 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.95735834 |
| 18 | Abnormality of B cell number (HP:0010975) | 2.92761505 |
| 19 | Syringomyelia (HP:0003396) | 2.92209808 |
| 20 | Spinal cord lesions (HP:0100561) | 2.92209808 |
| 21 | Severe global developmental delay (HP:0011344) | 2.87501074 |
| 22 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.75780469 |
| 23 | Recurrent cutaneous fungal infections (HP:0011370) | 2.74394925 |
| 24 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.74394925 |
| 25 | Thin bony cortex (HP:0002753) | 2.73007652 |
| 26 | Gingival bleeding (HP:0000225) | 2.72986673 |
| 27 | Abnormality of the costochondral junction (HP:0000919) | 2.71922856 |
| 28 | Fibular aplasia (HP:0002990) | 2.68732982 |
| 29 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.63442653 |
| 30 | Abnormality of lateral ventricle (HP:0030047) | 2.63236322 |
| 31 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.61929091 |
| 32 | Abnormality of T cell number (HP:0011839) | 2.61448214 |
| 33 | T lymphocytopenia (HP:0005403) | 2.51040914 |
| 34 | Alveolar cell carcinoma (HP:0006519) | 2.49275521 |
| 35 | Autoimmune thrombocytopenia (HP:0001973) | 2.49004391 |
| 36 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.45965665 |
| 37 | Female pseudohermaphroditism (HP:0010458) | 2.41382891 |
| 38 | B lymphocytopenia (HP:0010976) | 2.40625953 |
| 39 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.39529691 |
| 40 | Conjunctival telangiectasia (HP:0000524) | 2.37371861 |
| 41 | Degeneration of anterior horn cells (HP:0002398) | 2.35232942 |
| 42 | Abnormality of the anterior horn cell (HP:0006802) | 2.35232942 |
| 43 | Deep philtrum (HP:0002002) | 2.31508844 |
| 44 | Papillary thyroid carcinoma (HP:0002895) | 2.31164470 |
| 45 | Recurrent fungal infections (HP:0002841) | 2.29420857 |
| 46 | Abnormality of the 2nd finger (HP:0004100) | 2.28902086 |
| 47 | Glossoptosis (HP:0000162) | 2.27889701 |
| 48 | Spontaneous abortion (HP:0005268) | 2.26826833 |
| 49 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.26009816 |
| 50 | Obstructive lung disease (HP:0006536) | 2.25016270 |
| 51 | Chronic obstructive pulmonary disease (HP:0006510) | 2.25016270 |
| 52 | Peritonitis (HP:0002586) | 2.24263698 |
| 53 | Abnormality of the prostate (HP:0008775) | 2.23175691 |
| 54 | Abnormal epiphyseal ossification (HP:0010656) | 2.22722507 |
| 55 | Recurrent viral infections (HP:0004429) | 2.18467376 |
| 56 | Short middle phalanx of the 5th finger (HP:0004220) | 2.17856420 |
| 57 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.17424451 |
| 58 | Reticulocytopenia (HP:0001896) | 2.16617143 |
| 59 | Epistaxis (HP:0000421) | 2.15849919 |
| 60 | Ankyloglossia (HP:0010296) | 2.15055226 |
| 61 | Metaphyseal irregularity (HP:0003025) | 2.11982591 |
| 62 | Optic neuritis (HP:0100653) | 2.11243056 |
| 63 | Retrobulbar optic neuritis (HP:0100654) | 2.11243056 |
| 64 | Tinnitus (HP:0000360) | 2.09626852 |
| 65 | Reduced antithrombin III activity (HP:0001976) | 2.08375540 |
| 66 | Delayed epiphyseal ossification (HP:0002663) | 2.08266479 |
| 67 | Urticaria (HP:0001025) | 2.06001565 |
| 68 | Hyperglycinemia (HP:0002154) | 2.05219055 |
| 69 | Porencephaly (HP:0002132) | 2.02928048 |
| 70 | Abnormality of dental color (HP:0011073) | 1.99900332 |
| 71 | Death in infancy (HP:0001522) | 1.99870528 |
| 72 | Abnormality of the periventricular white matter (HP:0002518) | 1.98217877 |
| 73 | Epiphyseal stippling (HP:0010655) | 1.97699103 |
| 74 | Submucous cleft hard palate (HP:0000176) | 1.97160532 |
| 75 | Keratoconjunctivitis (HP:0001096) | 1.95820700 |
| 76 | Keratoconjunctivitis sicca (HP:0001097) | 1.91769559 |
| 77 | Abnormality of T cells (HP:0002843) | 1.90448333 |
| 78 | Acute myeloid leukemia (HP:0004808) | 1.90027579 |
| 79 | Acute lymphatic leukemia (HP:0006721) | 1.88633367 |
| 80 | Thyroid carcinoma (HP:0002890) | 1.88612112 |
| 81 | Vasculitis (HP:0002633) | 1.88533592 |
| 82 | Inflammation of the large intestine (HP:0002037) | 1.87917281 |
| 83 | Thickened calvaria (HP:0002684) | 1.86590019 |
| 84 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.86270331 |
| 85 | Beaking of vertebral bodies (HP:0004568) | 1.86021561 |
| 86 | Recurrent skin infections (HP:0001581) | 1.84743119 |
| 87 | Recurrent bacterial skin infections (HP:0005406) | 1.84677404 |
| 88 | Polyneuropathy (HP:0001271) | 1.83824832 |
| 89 | Leukocytosis (HP:0001974) | 1.82278776 |
| 90 | Thickened nuchal skin fold (HP:0000474) | 1.82266064 |
| 91 | Spondylolisthesis (HP:0003302) | 1.81853692 |
| 92 | Myositis (HP:0100614) | 1.81658142 |
| 93 | Recurrent abscess formation (HP:0002722) | 1.80833105 |
| 94 | Lip pit (HP:0100267) | 1.80683986 |
| 95 | Central scotoma (HP:0000603) | 1.80476131 |
| 96 | Hypoplastic iliac wings (HP:0002866) | 1.78900800 |
| 97 | Gastrointestinal infarctions (HP:0005244) | 1.78492836 |
| 98 | Median cleft lip (HP:0000161) | 1.77540409 |
| 99 | Primary adrenal insufficiency (HP:0008207) | 1.76032635 |
| 100 | Aplastic anemia (HP:0001915) | 1.75707709 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.13368625 |
| 2 | AKT3 | 4.11761406 |
| 3 | RIPK4 | 3.76870948 |
| 4 | CDC7 | 3.65740605 |
| 5 | MAP3K12 | 3.53058052 |
| 6 | CDK19 | 2.92532169 |
| 7 | FLT3 | 2.48595874 |
| 8 | KIT | 2.42306362 |
| 9 | FES | 2.36529454 |
| 10 | BMPR2 | 2.32134289 |
| 11 | MAP3K2 | 2.16600790 |
| 12 | PIK3CG | 2.13387384 |
| 13 | TEC | 2.09492631 |
| 14 | TAOK3 | 2.02377133 |
| 15 | CSF1R | 1.98095020 |
| 16 | GRK6 | 1.96752851 |
| 17 | CLK1 | 1.72241446 |
| 18 | JAK3 | 1.69225515 |
| 19 | ADRBK2 | 1.68624377 |
| 20 | PASK | 1.61057070 |
| 21 | BLK | 1.56932929 |
| 22 | MAP3K7 | 1.46674821 |
| 23 | MYLK | 1.44540707 |
| 24 | SYK | 1.32661553 |
| 25 | TLK1 | 1.24270905 |
| 26 | TNIK | 1.23812270 |
| 27 | NLK | 1.18719856 |
| 28 | PDK2 | 1.15897879 |
| 29 | MAP2K3 | 1.13539475 |
| 30 | MATK | 1.07610937 |
| 31 | TRPM7 | 1.06211729 |
| 32 | PRKD3 | 1.05608078 |
| 33 | STK24 | 1.05323276 |
| 34 | OXSR1 | 1.04616157 |
| 35 | HCK | 1.04210797 |
| 36 | TNK2 | 1.02153230 |
| 37 | DYRK1B | 1.01956946 |
| 38 | ZAK | 0.97546837 |
| 39 | IKBKE | 0.97292044 |
| 40 | SRPK1 | 0.95767347 |
| 41 | JAK1 | 0.94245967 |
| 42 | LCK | 0.92983803 |
| 43 | BRAF | 0.91645990 |
| 44 | LYN | 0.90280427 |
| 45 | JAK2 | 0.89370543 |
| 46 | BTK | 0.89121811 |
| 47 | SGK2 | 0.88299528 |
| 48 | ICK | 0.87392784 |
| 49 | MAP4K1 | 0.86878305 |
| 50 | PTK2B | 0.84502812 |
| 51 | MAP3K13 | 0.83219119 |
| 52 | IKBKB | 0.75605288 |
| 53 | FGR | 0.73758105 |
| 54 | CSK | 0.73411474 |
| 55 | ITK | 0.73057929 |
| 56 | FRK | 0.69618405 |
| 57 | RPS6KA5 | 0.69098648 |
| 58 | ADRBK1 | 0.68963639 |
| 59 | ERBB2 | 0.66878003 |
| 60 | MAP3K1 | 0.62370723 |
| 61 | PRKCQ | 0.60221751 |
| 62 | MAP4K2 | 0.56794896 |
| 63 | TYK2 | 0.52345608 |
| 64 | PRKG1 | 0.51912645 |
| 65 | DAPK3 | 0.51804837 |
| 66 | CAMK1 | 0.49658505 |
| 67 | PIM1 | 0.47591387 |
| 68 | IRAK1 | 0.46901651 |
| 69 | STK4 | 0.45596653 |
| 70 | PBK | 0.45571231 |
| 71 | GRK5 | 0.44935664 |
| 72 | SCYL2 | 0.44515585 |
| 73 | PTK6 | 0.43854435 |
| 74 | MAP3K11 | 0.43439282 |
| 75 | GRK7 | 0.42863740 |
| 76 | PRKAA2 | 0.41842353 |
| 77 | SGK3 | 0.40959884 |
| 78 | IGF1R | 0.40753964 |
| 79 | IRAK4 | 0.39778879 |
| 80 | DAPK1 | 0.39035607 |
| 81 | SGK1 | 0.39002664 |
| 82 | OBSCN | 0.37261711 |
| 83 | MAP2K2 | 0.36964021 |
| 84 | PKN1 | 0.36261596 |
| 85 | ILK | 0.35849680 |
| 86 | ZAP70 | 0.34809028 |
| 87 | ABL1 | 0.33965341 |
| 88 | TGFBR2 | 0.33644311 |
| 89 | CSNK2A2 | 0.32052986 |
| 90 | AURKB | 0.31115125 |
| 91 | INSRR | 0.30539084 |
| 92 | CDK6 | 0.30248381 |
| 93 | EIF2AK3 | 0.29667044 |
| 94 | MAP2K4 | 0.29559785 |
| 95 | EGFR | 0.28394169 |
| 96 | PAK1 | 0.27684939 |
| 97 | MARK3 | 0.26853577 |
| 98 | PRKACA | 0.25838001 |
| 99 | PRKCD | 0.25693234 |
| 100 | PRKCB | 0.25687617 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 6.01006560 |
| 2 | Asthma_Homo sapiens_hsa05310 | 4.70755340 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.18759075 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.13368469 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.09057838 |
| 6 | Leishmaniasis_Homo sapiens_hsa05140 | 2.85244355 |
| 7 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.77771243 |
| 8 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.59056757 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.50303723 |
| 10 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.47609323 |
| 11 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.32601625 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.01301345 |
| 13 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.87276963 |
| 14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.83643190 |
| 15 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.80629495 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.76894270 |
| 17 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.70849396 |
| 18 | Ribosome_Homo sapiens_hsa03010 | 1.67668118 |
| 19 | Viral myocarditis_Homo sapiens_hsa05416 | 1.38911553 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.36554219 |
| 21 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.36069682 |
| 22 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.34247838 |
| 23 | Tuberculosis_Homo sapiens_hsa05152 | 1.28815756 |
| 24 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.23836139 |
| 25 | Olfactory transduction_Homo sapiens_hsa04740 | 1.19630802 |
| 26 | Platelet activation_Homo sapiens_hsa04611 | 1.14536945 |
| 27 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.10978142 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 1.06466525 |
| 29 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.03476046 |
| 30 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.02540069 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.00229242 |
| 32 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.97696753 |
| 33 | Influenza A_Homo sapiens_hsa05164 | 0.97151536 |
| 34 | Morphine addiction_Homo sapiens_hsa05032 | 0.96417651 |
| 35 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.91626058 |
| 36 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.91427990 |
| 37 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.91016972 |
| 38 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.90039069 |
| 39 | Malaria_Homo sapiens_hsa05144 | 0.89861279 |
| 40 | Parkinsons disease_Homo sapiens_hsa05012 | 0.88072165 |
| 41 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.85418526 |
| 42 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.83819064 |
| 43 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.83383242 |
| 44 | Alcoholism_Homo sapiens_hsa05034 | 0.81399908 |
| 45 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.80604492 |
| 46 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.77147469 |
| 47 | Legionellosis_Homo sapiens_hsa05134 | 0.75821046 |
| 48 | Thyroid cancer_Homo sapiens_hsa05216 | 0.75658955 |
| 49 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.64761776 |
| 50 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.62186167 |
| 51 | Protein export_Homo sapiens_hsa03060 | 0.62160282 |
| 52 | Phototransduction_Homo sapiens_hsa04744 | 0.61861483 |
| 53 | Salmonella infection_Homo sapiens_hsa05132 | 0.57780291 |
| 54 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.57743657 |
| 55 | Huntingtons disease_Homo sapiens_hsa05016 | 0.57663628 |
| 56 | RNA polymerase_Homo sapiens_hsa03020 | 0.57616508 |
| 57 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.57113298 |
| 58 | Measles_Homo sapiens_hsa05162 | 0.56964770 |
| 59 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.55608561 |
| 60 | Circadian entrainment_Homo sapiens_hsa04713 | 0.55046155 |
| 61 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.53549795 |
| 62 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.52957366 |
| 63 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.52386111 |
| 64 | GABAergic synapse_Homo sapiens_hsa04727 | 0.52230698 |
| 65 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.51655512 |
| 66 | Phagosome_Homo sapiens_hsa04145 | 0.49884176 |
| 67 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.49383770 |
| 68 | Base excision repair_Homo sapiens_hsa03410 | 0.48530857 |
| 69 | Basal transcription factors_Homo sapiens_hsa03022 | 0.48284672 |
| 70 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.47803791 |
| 71 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.46219506 |
| 72 | Alzheimers disease_Homo sapiens_hsa05010 | 0.46096701 |
| 73 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.45678592 |
| 74 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45160901 |
| 75 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.44091023 |
| 76 | Proteasome_Homo sapiens_hsa03050 | 0.42146456 |
| 77 | Long-term potentiation_Homo sapiens_hsa04720 | 0.40694902 |
| 78 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.39243879 |
| 79 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.39122781 |
| 80 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.37478021 |
| 81 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.36691541 |
| 82 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.35557742 |
| 83 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.35460390 |
| 84 | Renin secretion_Homo sapiens_hsa04924 | 0.32937650 |
| 85 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.31124546 |
| 86 | Purine metabolism_Homo sapiens_hsa00230 | 0.30890969 |
| 87 | Shigellosis_Homo sapiens_hsa05131 | 0.30518782 |
| 88 | Salivary secretion_Homo sapiens_hsa04970 | 0.26499206 |
| 89 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.25432760 |
| 90 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.24384894 |
| 91 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.24339731 |
| 92 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.23260325 |
| 93 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.22533692 |
| 94 | Bladder cancer_Homo sapiens_hsa05219 | 0.22292158 |
| 95 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.22191028 |
| 96 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.21580043 |
| 97 | Pertussis_Homo sapiens_hsa05133 | 0.21280705 |
| 98 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.19154640 |
| 99 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.18416495 |
| 100 | DNA replication_Homo sapiens_hsa03030 | 0.16962568 |

