

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 4.64322086 |
| 2 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 4.64322086 |
| 3 | chondrocyte proliferation (GO:0035988) | 4.58455037 |
| 4 | sequestering of extracellular ligand from receptor (GO:0035581) | 4.55472631 |
| 5 | collagen fibril organization (GO:0030199) | 4.41724441 |
| 6 | Golgi transport vesicle coating (GO:0048200) | 4.35453971 |
| 7 | COPI coating of Golgi vesicle (GO:0048205) | 4.35453971 |
| 8 | skin morphogenesis (GO:0043589) | 4.11841937 |
| 9 | extracellular fibril organization (GO:0043206) | 4.09452867 |
| 10 | protein heterotrimerization (GO:0070208) | 3.98047385 |
| 11 | paraxial mesoderm development (GO:0048339) | 3.95990258 |
| 12 | negative regulation of stem cell proliferation (GO:2000647) | 3.91515087 |
| 13 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.91052775 |
| 14 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.86544179 |
| 15 | cell adhesion mediated by integrin (GO:0033627) | 3.86242296 |
| 16 | protein retention in ER lumen (GO:0006621) | 3.78617454 |
| 17 | mesenchymal-epithelial cell signaling (GO:0060638) | 3.77360765 |
| 18 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 3.74143807 |
| 19 | glomerulus development (GO:0032835) | 3.73113136 |
| 20 | cell differentiation involved in metanephros development (GO:0072202) | 3.69175644 |
| 21 | extracellular negative regulation of signal transduction (GO:1900116) | 3.65168274 |
| 22 | extracellular regulation of signal transduction (GO:1900115) | 3.65168274 |
| 23 | kidney mesenchyme development (GO:0072074) | 3.64223318 |
| 24 | nuclear pore complex assembly (GO:0051292) | 3.63176536 |
| 25 | glomerular basement membrane development (GO:0032836) | 3.60365144 |
| 26 | neural crest cell development (GO:0014032) | 3.59485413 |
| 27 | fibril organization (GO:0097435) | 3.58779544 |
| 28 | mitotic chromosome condensation (GO:0007076) | 3.58048153 |
| 29 | metanephric mesenchyme development (GO:0072075) | 3.56586494 |
| 30 | bone trabecula formation (GO:0060346) | 3.53353678 |
| 31 | cell migration involved in heart development (GO:0060973) | 3.52303393 |
| 32 | smooth muscle tissue development (GO:0048745) | 3.51526146 |
| 33 | lymph vessel development (GO:0001945) | 3.48160294 |
| 34 | cell proliferation involved in kidney development (GO:0072111) | 3.47545166 |
| 35 | DNA unwinding involved in DNA replication (GO:0006268) | 3.45438834 |
| 36 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.44541090 |
| 37 | dermatan sulfate biosynthetic process (GO:0030208) | 3.42822770 |
| 38 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.39907671 |
| 39 | definitive hemopoiesis (GO:0060216) | 3.39813872 |
| 40 | muscle cell migration (GO:0014812) | 3.38576360 |
| 41 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.36525239 |
| 42 | regulation of transforming growth factor beta2 production (GO:0032909) | 3.28973250 |
| 43 | peptidyl-proline hydroxylation (GO:0019511) | 3.27831774 |
| 44 | hippo signaling (GO:0035329) | 3.27155754 |
| 45 | nuclear pore organization (GO:0006999) | 3.26843967 |
| 46 | keratan sulfate catabolic process (GO:0042340) | 3.24930006 |
| 47 | endothelial cell morphogenesis (GO:0001886) | 3.24542051 |
| 48 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.24190374 |
| 49 | collagen metabolic process (GO:0032963) | 3.23323220 |
| 50 | collagen catabolic process (GO:0030574) | 3.19446265 |
| 51 | lung vasculature development (GO:0060426) | 3.17552389 |
| 52 | positive regulation of smooth muscle cell migration (GO:0014911) | 3.17107042 |
| 53 | COPII vesicle coating (GO:0048208) | 3.16768558 |
| 54 | regulation of interleukin-8 secretion (GO:2000482) | 3.15447410 |
| 55 | dermatan sulfate metabolic process (GO:0030205) | 3.15201870 |
| 56 | mesenchymal cell development (GO:0014031) | 3.14950153 |
| 57 | protein hydroxylation (GO:0018126) | 3.13574177 |
| 58 | notochord development (GO:0030903) | 3.13116335 |
| 59 | basement membrane organization (GO:0071711) | 3.10627191 |
| 60 | type B pancreatic cell proliferation (GO:0044342) | 3.09825079 |
| 61 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 3.07456539 |
| 62 | negative regulation of cartilage development (GO:0061037) | 3.07440650 |
| 63 | mesenchymal cell differentiation (GO:0048762) | 3.07426865 |
| 64 | gonadal mesoderm development (GO:0007506) | 3.06811016 |
| 65 | regulation of male gonad development (GO:2000018) | 3.04858515 |
| 66 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.04821707 |
| 67 | negative regulation of osteoblast proliferation (GO:0033689) | 3.00377895 |
| 68 | mitotic cytokinesis (GO:0000281) | 2.99085993 |
| 69 | mitotic sister chromatid segregation (GO:0000070) | 2.98877527 |
| 70 | chondrocyte development (GO:0002063) | 2.98670880 |
| 71 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 2.97042370 |
| 72 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.96519712 |
| 73 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.95162709 |
| 74 | positive regulation of male gonad development (GO:2000020) | 2.93470731 |
| 75 | protein localization to cell surface (GO:0034394) | 2.92955189 |
| 76 | sister chromatid segregation (GO:0000819) | 2.92570866 |
| 77 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.91133865 |
| 78 | axon extension involved in axon guidance (GO:0048846) | 2.91133865 |
| 79 | wound healing, spreading of epidermal cells (GO:0035313) | 2.91018371 |
| 80 | negative regulation of mast cell activation (GO:0033004) | 2.90126154 |
| 81 | cartilage morphogenesis (GO:0060536) | 2.88447448 |
| 82 | positive regulation of osteoblast proliferation (GO:0033690) | 2.88176538 |
| 83 | multicellular organismal catabolic process (GO:0044243) | 2.87866462 |
| 84 | regulation of establishment of planar polarity (GO:0090175) | 2.87541092 |
| 85 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.87439808 |
| 86 | cochlea morphogenesis (GO:0090103) | 2.86487934 |
| 87 | stem cell development (GO:0048864) | 2.85921233 |
| 88 | blood vessel maturation (GO:0001955) | 2.84804995 |
| 89 | organ induction (GO:0001759) | 2.84698994 |
| 90 | endothelial cell proliferation (GO:0001935) | 2.83949206 |
| 91 | mesonephric tubule development (GO:0072164) | 2.81958855 |
| 92 | multicellular organismal metabolic process (GO:0044236) | 2.81633998 |
| 93 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.80878238 |
| 94 | ureteric bud development (GO:0001657) | 2.78807455 |
| 95 | mesenchymal cell proliferation (GO:0010463) | 2.78664771 |
| 96 | extracellular matrix assembly (GO:0085029) | 2.78070424 |
| 97 | cardiac epithelial to mesenchymal transition (GO:0060317) | 2.77605901 |
| 98 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.77166506 |
| 99 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.76730475 |
| 100 | embryonic cranial skeleton morphogenesis (GO:0048701) | 2.76598130 |
| 101 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.75904510 |
| 102 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.75703109 |
| 103 | regulation of mitotic spindle organization (GO:0060236) | 2.73330327 |
| 104 | substrate-dependent cell migration (GO:0006929) | 2.73312838 |
| 105 | cellular response to vitamin (GO:0071295) | 2.73126821 |
| 106 | embryonic skeletal joint morphogenesis (GO:0060272) | 2.72743956 |
| 107 | mesonephric epithelium development (GO:0072163) | 2.71989751 |
| 108 | cell proliferation involved in metanephros development (GO:0072203) | 2.69943011 |
| 109 | cytoskeleton-dependent cytokinesis (GO:0061640) | 2.68677393 |
| 110 | ventricular cardiac muscle cell development (GO:0055015) | 2.67976324 |
| 111 | desmosome organization (GO:0002934) | 2.67690957 |
| 112 | non-canonical Wnt signaling pathway (GO:0035567) | 2.66699781 |
| 113 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.65709796 |
| 114 | regulation of mesenchymal cell proliferation (GO:0010464) | 2.64961799 |
| 115 | pore complex assembly (GO:0046931) | 2.64835748 |
| 116 | lymphangiogenesis (GO:0001946) | 2.63276867 |
| 117 | outer ear morphogenesis (GO:0042473) | 2.62880468 |
| 118 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.61943268 |
| 119 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.59850060 |
| 120 | facial nerve structural organization (GO:0021612) | 2.59539176 |
| 121 | wound healing, spreading of cells (GO:0044319) | 2.59465859 |
| 122 | ganglion development (GO:0061548) | 2.59005955 |
| 123 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.58536319 |
| 124 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 2.57782311 |
| 125 | cellular response to vitamin D (GO:0071305) | 2.56808946 |
| 126 | regulation of chondrocyte differentiation (GO:0032330) | 2.55589727 |
| 127 | extracellular matrix disassembly (GO:0022617) | 2.55462337 |
| 128 | cell differentiation involved in kidney development (GO:0061005) | 2.55157859 |
| 129 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.53965621 |
| 130 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 2.52768542 |
| 131 | endothelium development (GO:0003158) | 2.52697834 |
| 132 | vesicle coating (GO:0006901) | 2.52658945 |
| 133 | extracellular matrix organization (GO:0030198) | 2.52348406 |
| 134 | extracellular structure organization (GO:0043062) | 2.51257642 |
| 135 | regulation of endothelial cell differentiation (GO:0045601) | 2.51056015 |
| 136 | epithelial to mesenchymal transition (GO:0001837) | 2.50562462 |
| 137 | organ formation (GO:0048645) | 2.50102565 |
| 138 | phagocytosis, engulfment (GO:0006911) | 2.49532796 |
| 139 | mesodermal cell differentiation (GO:0048333) | 2.49311283 |
| 140 | bone remodeling (GO:0046849) | 2.49078148 |
| 141 | endocardial cushion development (GO:0003197) | 2.48791681 |
| 142 | mitotic sister chromatid cohesion (GO:0007064) | 2.48506297 |
| 143 | regulation of pigment cell differentiation (GO:0050932) | 2.46688470 |
| 144 | endodermal cell differentiation (GO:0035987) | 2.46392868 |
| 145 | positive regulation of mesenchymal cell proliferation (GO:0002053) | 2.46323542 |
| 146 | protein localization to chromosome, centromeric region (GO:0071459) | 2.45528158 |
| 147 | positive regulation of cartilage development (GO:0061036) | 2.44654129 |
| 148 | negative regulation of leukocyte chemotaxis (GO:0002689) | 2.44061547 |
| 149 | chromosome condensation (GO:0030261) | 2.43682197 |
| 150 | cell-substrate junction assembly (GO:0007044) | 2.43323347 |
| 151 | detection of molecule of bacterial origin (GO:0032490) | 2.42779196 |
| 152 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 2.42746317 |
| 153 | heterochromatin organization (GO:0070828) | 2.42315563 |
| 154 | craniofacial suture morphogenesis (GO:0097094) | 2.42187604 |
| 155 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.41592517 |
| 156 | regulation of osteoblast proliferation (GO:0033688) | 2.40392192 |
| 157 | protein maturation by protein folding (GO:0022417) | 2.38523654 |
| 158 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.38504887 |
| 159 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 2.38432004 |
| 160 | atrial septum morphogenesis (GO:0060413) | 2.38342843 |
| 161 | protein localization to kinetochore (GO:0034501) | 2.38151560 |
| 162 | regulation of cartilage development (GO:0061035) | 2.38143382 |
| 163 | cellular response to BMP stimulus (GO:0071773) | 2.37813577 |
| 164 | response to BMP (GO:0071772) | 2.37813577 |
| 165 | Notch signaling involved in heart development (GO:0061314) | 2.37311036 |
| 166 | apoptotic cell clearance (GO:0043277) | 2.37274323 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.42384556 |
| 2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.50151049 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.06534028 |
| 4 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 4.03664634 |
| 5 | AR_21909140_ChIP-Seq_LNCAP_Human | 4.01396388 |
| 6 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.57938638 |
| 7 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.11118101 |
| 8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.02034819 |
| 9 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 2.88345761 |
| 10 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.87502981 |
| 11 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.68611984 |
| 12 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.63044582 |
| 13 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.53603184 |
| 14 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.52998533 |
| 15 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.50363515 |
| 16 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.46406585 |
| 17 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.43551743 |
| 18 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.42185171 |
| 19 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.36159703 |
| 20 | * CJUN_26792858_Chip-Seq_BT549_Human | 2.35491627 |
| 21 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.35365741 |
| 22 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.33042828 |
| 23 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.23914865 |
| 24 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.22209210 |
| 25 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.19770828 |
| 26 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.19082554 |
| 27 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.17842062 |
| 28 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.07503817 |
| 29 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.03469784 |
| 30 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.97604327 |
| 31 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.97604327 |
| 32 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.96493346 |
| 33 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.96380485 |
| 34 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.95481093 |
| 35 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.93049847 |
| 36 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.92926088 |
| 37 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.91724727 |
| 38 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.90571628 |
| 39 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.89842939 |
| 40 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.86951878 |
| 41 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.85629770 |
| 42 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.85533143 |
| 43 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.85052027 |
| 44 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.81417014 |
| 45 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.80040062 |
| 46 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.75639542 |
| 47 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.75064210 |
| 48 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.74482109 |
| 49 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.73836750 |
| 50 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.69681057 |
| 51 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.66715090 |
| 52 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.65389526 |
| 53 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.64078300 |
| 54 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.63956164 |
| 55 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.63090089 |
| 56 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.62589926 |
| 57 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.62137728 |
| 58 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.62018523 |
| 59 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.61802182 |
| 60 | EWS_26573619_Chip-Seq_HEK293_Human | 1.60871653 |
| 61 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.60852625 |
| 62 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.60837667 |
| 63 | * BRD4_25478319_ChIP-Seq_HGPS_Human | 1.60782340 |
| 64 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.59438001 |
| 65 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.56965777 |
| 66 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.56372152 |
| 67 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.49633556 |
| 68 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.47339945 |
| 69 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.46888336 |
| 70 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.46607774 |
| 71 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.44621686 |
| 72 | * SOX2_20726797_ChIP-Seq_SW620_Human | 1.44324639 |
| 73 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.43188795 |
| 74 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.41872943 |
| 75 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.41457664 |
| 76 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.40191313 |
| 77 | FUS_26573619_Chip-Seq_HEK293_Human | 1.40125251 |
| 78 | P300_19829295_ChIP-Seq_ESCs_Human | 1.39308838 |
| 79 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.38963416 |
| 80 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.37731275 |
| 81 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.36340301 |
| 82 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.34693484 |
| 83 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.34372270 |
| 84 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.34152968 |
| 85 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.34010743 |
| 86 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.33624249 |
| 87 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.32391882 |
| 88 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.32218890 |
| 89 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.31998326 |
| 90 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.31594537 |
| 91 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.31594537 |
| 92 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.29520052 |
| 93 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.29061936 |
| 94 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.28461861 |
| 95 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.28298885 |
| 96 | TP53_16413492_ChIP-PET_HCT116_Human | 1.28075377 |
| 97 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.27193990 |
| 98 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.26911306 |
| 99 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.26823135 |
| 100 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.26622527 |
| 101 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.24420494 |
| 102 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.24409627 |
| 103 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.22303591 |
| 104 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.22249388 |
| 105 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.21635345 |
| 106 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.21336409 |
| 107 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.20972025 |
| 108 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.20962582 |
| 109 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.19542569 |
| 110 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.19534715 |
| 111 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.18859277 |
| 112 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.18072755 |
| 113 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.17379894 |
| 114 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.17040692 |
| 115 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.16012992 |
| 116 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16012207 |
| 117 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.15820698 |
| 118 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15720165 |
| 119 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.15296867 |
| 120 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.13858110 |
| 121 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.13858110 |
| 122 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13450156 |
| 123 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.13040481 |
| 124 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.12440965 |
| 125 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.11894417 |
| 126 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.10308151 |
| 127 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.09896843 |
| 128 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.09770908 |
| 129 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.09671852 |
| 130 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.09534306 |
| 131 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.08511447 |
| 132 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.08270237 |
| 133 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.08251707 |
| 134 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.07409639 |
| 135 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.06011687 |
| 136 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.03305352 |
| 137 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.03217061 |
| 138 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.02639362 |
| 139 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.02094361 |
| 140 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.01777853 |
| 141 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.00768881 |
| 142 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.98396816 |
| 143 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.97935065 |
| 144 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.97778063 |
| 145 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.97271847 |
| 146 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.96815885 |
| 147 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.96399758 |
| 148 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.95745085 |
| 149 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.95417069 |
| 150 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.95186002 |
| 151 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.95008025 |
| 152 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.95005778 |
| 153 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.94916792 |
| 154 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.94910423 |
| 155 | * JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.94862347 |
| 156 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.94621630 |
| 157 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.94596634 |
| 158 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.94561536 |
| 159 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.94389669 |
| 160 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.94012380 |
| 161 | * FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.92497586 |
| 162 | * TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.92371559 |
| 163 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.92216045 |
| 164 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 0.89014959 |
| 165 | * JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.88284873 |
| 166 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.87419811 |
| 167 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.87415380 |
| 168 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.87282529 |
| 169 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.86535507 |
| 170 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.86535507 |
| 171 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.85237845 |
| 172 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.84926458 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008438_abnormal_cutaneous_collagen | 6.86126206 |
| 2 | MP0005503_abnormal_tendon_morphology | 5.41888014 |
| 3 | MP0005275_abnormal_skin_tensile | 4.07874490 |
| 4 | MP0003279_aneurysm | 3.13015895 |
| 5 | MP0004272_abnormal_basement_membrane | 3.12540027 |
| 6 | MP0001958_emphysema | 2.78028234 |
| 7 | MP0010352_gastrointestinal_tract_polyps | 2.74225675 |
| 8 | MP0002877_abnormal_melanocyte_morpholog | 2.67302602 |
| 9 | MP0010368_abnormal_lymphatic_system | 2.45727752 |
| 10 | MP0005257_abnormal_intraocular_pressure | 2.22780211 |
| 11 | MP0003941_abnormal_skin_development | 2.15268139 |
| 12 | MP0005508_abnormal_skeleton_morphology | 2.14096397 |
| 13 | MP0001879_abnormal_lymphatic_vessel | 2.13544411 |
| 14 | MP0010030_abnormal_orbit_morphology | 2.09946936 |
| 15 | MP0009250_abnormal_appendicular_skeleto | 2.09206441 |
| 16 | MP0002249_abnormal_larynx_morphology | 2.04407525 |
| 17 | MP0006054_spinal_hemorrhage | 1.98390015 |
| 18 | MP0005171_absent_coat_pigmentation | 1.90218665 |
| 19 | MP0000566_synostosis | 1.85002229 |
| 20 | MP0009384_cardiac_valve_regurgitation | 1.81224413 |
| 21 | MP0003385_abnormal_body_wall | 1.76834594 |
| 22 | MP0005623_abnormal_meninges_morphology | 1.75208498 |
| 23 | MP0002282_abnormal_trachea_morphology | 1.74185861 |
| 24 | MP0000767_abnormal_smooth_muscle | 1.70827777 |
| 25 | MP0002060_abnormal_skin_morphology | 1.68791512 |
| 26 | MP0001188_hyperpigmentation | 1.65076633 |
| 27 | MP0002108_abnormal_muscle_morphology | 1.64928935 |
| 28 | MP0001542_abnormal_bone_strength | 1.64376416 |
| 29 | MP0002938_white_spotting | 1.58733025 |
| 30 | MP0009697_abnormal_copulation | 1.57728253 |
| 31 | MP0009379_abnormal_foot_pigmentation | 1.55784544 |
| 32 | MP0003942_abnormal_urinary_system | 1.54475479 |
| 33 | MP0005367_renal/urinary_system_phenotyp | 1.51434880 |
| 34 | MP0000516_abnormal_urinary_system | 1.51434880 |
| 35 | MP0000163_abnormal_cartilage_morphology | 1.47325452 |
| 36 | MP0002295_abnormal_pulmonary_circulatio | 1.46825292 |
| 37 | MP0000049_abnormal_middle_ear | 1.40693686 |
| 38 | MP0001299_abnormal_eye_distance/ | 1.39035443 |
| 39 | MP0002933_joint_inflammation | 1.33891988 |
| 40 | MP0003566_abnormal_cell_adhesion | 1.33467818 |
| 41 | MP0009780_abnormal_chondrocyte_physiolo | 1.31955246 |
| 42 | MP0005390_skeleton_phenotype | 1.30478129 |
| 43 | MP0002009_preneoplasia | 1.27058883 |
| 44 | MP0002115_abnormal_skeleton_extremities | 1.22202019 |
| 45 | MP0005023_abnormal_wound_healing | 1.19967023 |
| 46 | MP0000751_myopathy | 1.16675937 |
| 47 | MP0003828_pulmonary_edema | 1.16413011 |
| 48 | MP0003115_abnormal_respiratory_system | 1.15089143 |
| 49 | MP0002132_abnormal_respiratory_system | 1.13934363 |
| 50 | MP0002113_abnormal_skeleton_development | 1.13358270 |
| 51 | MP0000534_abnormal_ureter_morphology | 1.13094882 |
| 52 | MP0008932_abnormal_embryonic_tissue | 1.12725323 |
| 53 | MP0003705_abnormal_hypodermis_morpholog | 1.10586529 |
| 54 | MP0010094_abnormal_chromosome_stability | 1.10170408 |
| 55 | MP0002896_abnormal_bone_mineralization | 1.09465043 |
| 56 | MP0004957_abnormal_blastocyst_morpholog | 1.08468805 |
| 57 | MP0000013_abnormal_adipose_tissue | 1.07757940 |
| 58 | MP0002109_abnormal_limb_morphology | 1.06455207 |
| 59 | MP0003111_abnormal_nucleus_morphology | 1.05894377 |
| 60 | MP0005076_abnormal_cell_differentiation | 1.05145764 |
| 61 | MP0005408_hypopigmentation | 1.04261654 |
| 62 | MP0004883_abnormal_blood_vessel | 1.03800534 |
| 63 | MP0001175_abnormal_lung_morphology | 1.03441466 |
| 64 | MP0000537_abnormal_urethra_morphology | 1.03114556 |
| 65 | MP0003755_abnormal_palate_morphology | 1.02989136 |
| 66 | MP0004134_abnormal_chest_morphology | 1.02847413 |
| 67 | MP0002133_abnormal_respiratory_system | 1.02700393 |
| 68 | MP0005388_respiratory_system_phenotype | 1.02700393 |
| 69 | MP0004782_abnormal_surfactant_physiolog | 0.99826216 |
| 70 | MP0002932_abnormal_joint_morphology | 0.98043727 |
| 71 | MP0000762_abnormal_tongue_morphology | 0.97380374 |
| 72 | MP0008007_abnormal_cellular_replicative | 0.96795539 |
| 73 | MP0001243_abnormal_dermal_layer | 0.96538311 |
| 74 | MP0000678_abnormal_parathyroid_gland | 0.95760448 |
| 75 | MP0005595_abnormal_vascular_smooth | 0.95738210 |
| 76 | MP0002998_abnormal_bone_remodeling | 0.93795112 |
| 77 | MP0010234_abnormal_vibrissa_follicle | 0.93792616 |
| 78 | MP0002396_abnormal_hematopoietic_system | 0.92961455 |
| 79 | MP0000372_irregular_coat_pigmentation | 0.92185189 |
| 80 | MP0000432_abnormal_head_morphology | 0.92137778 |
| 81 | MP0001177_atelectasis | 0.91467314 |
| 82 | MP0003943_abnormal_hepatobiliary_system | 0.91403975 |
| 83 | MP0003937_abnormal_limbs/digits/tail_de | 0.91081595 |
| 84 | MP0000462_abnormal_digestive_system | 0.90294420 |
| 85 | MP0002697_abnormal_eye_size | 0.90204668 |
| 86 | MP0002177_abnormal_outer_ear | 0.85423700 |
| 87 | MP0003045_fibrosis | 0.85418415 |
| 88 | MP0000681_abnormal_thyroid_gland | 0.85141756 |
| 89 | MP0005409_darkened_coat_color | 0.84371262 |
| 90 | MP0000003_abnormal_adipose_tissue | 0.84160580 |
| 91 | MP0003724_increased_susceptibility_to | 0.83707730 |
| 92 | MP0003950_abnormal_plasma_membrane | 0.83478795 |
| 93 | MP0002168_other_aberrant_phenotype | 0.83405569 |
| 94 | MP0001661_extended_life_span | 0.83320520 |
| 95 | MP0002085_abnormal_embryonic_tissue | 0.83058992 |
| 96 | MP0002116_abnormal_craniofacial_bone | 0.82892897 |
| 97 | MP0001346_abnormal_lacrimal_gland | 0.82759600 |
| 98 | MP0010307_abnormal_tumor_latency | 0.82647745 |
| 99 | MP0000428_abnormal_craniofacial_morphol | 0.82337363 |
| 100 | MP0004233_abnormal_muscle_weight | 0.82192423 |
| 101 | MP0009053_abnormal_anal_canal | 0.82119413 |
| 102 | MP0003935_abnormal_craniofacial_develop | 0.81759253 |
| 103 | MP0005380_embryogenesis_phenotype | 0.81603643 |
| 104 | MP0001672_abnormal_embryogenesis/_devel | 0.81603643 |
| 105 | MP0002092_abnormal_eye_morphology | 0.81338050 |
| 106 | MP0001270_distended_abdomen | 0.81026748 |
| 107 | MP0002084_abnormal_developmental_patter | 0.80695353 |
| 108 | MP0002114_abnormal_axial_skeleton | 0.80477665 |
| 109 | MP0000343_altered_response_to | 0.79713924 |
| 110 | MP0005197_abnormal_uvea_morphology | 0.79510635 |
| 111 | MP0002086_abnormal_extraembryonic_tissu | 0.78958404 |
| 112 | MP0002128_abnormal_blood_circulation | 0.78854077 |
| 113 | MP0005084_abnormal_gallbladder_morpholo | 0.78531527 |
| 114 | MP0005164_abnormal_response_to | 0.77273630 |
| 115 | MP0005248_abnormal_Harderian_gland | 0.76975464 |
| 116 | MP0000350_abnormal_cell_proliferation | 0.76908608 |
| 117 | MP0003077_abnormal_cell_cycle | 0.76805992 |
| 118 | MP0002148_abnormal_hypersensitivity_rea | 0.76731754 |
| 119 | MP0003795_abnormal_bone_structure | 0.75898478 |
| 120 | MP0003984_embryonic_growth_retardation | 0.75691159 |
| 121 | MP0002233_abnormal_nose_morphology | 0.75205606 |
| 122 | MP0000759_abnormal_skeletal_muscle | 0.73602673 |
| 123 | MP0002925_abnormal_cardiovascular_devel | 0.73537567 |
| 124 | MP0008057_abnormal_DNA_replication | 0.73284413 |
| 125 | MP0005193_abnormal_anterior_eye | 0.72893152 |
| 126 | MP0002102_abnormal_ear_morphology | 0.72585300 |
| 127 | MP0000613_abnormal_salivary_gland | 0.72330595 |
| 128 | MP0010386_abnormal_urinary_bladder | 0.72233022 |
| 129 | MP0003122_maternal_imprinting | 0.71715995 |
| 130 | MP0002088_abnormal_embryonic_growth/wei | 0.71653618 |
| 131 | MP0001614_abnormal_blood_vessel | 0.70203568 |
| 132 | MP0000733_abnormal_muscle_development | 0.68813214 |
| 133 | MP0002163_abnormal_gland_morphology | 0.68526295 |
| 134 | MP0003091_abnormal_cell_migration | 0.68503872 |
| 135 | MP0004858_abnormal_nervous_system | 0.68386263 |
| 136 | MP0001286_abnormal_eye_development | 0.68278427 |
| 137 | MP0001533_abnormal_skeleton_physiology | 0.66614816 |
| 138 | MP0001697_abnormal_embryo_size | 0.66375938 |
| 139 | MP0002928_abnormal_bile_duct | 0.66370118 |
| 140 | MP0006138_congestive_heart_failure | 0.66315620 |
| 141 | MP0001348_abnormal_lacrimal_gland | 0.65723139 |
| 142 | MP0003283_abnormal_digestive_organ | 0.65618632 |
| 143 | MP0000249_abnormal_blood_vessel | 0.64176573 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Protrusio acetabuli (HP:0003179) | 5.27744141 |
| 2 | Premature rupture of membranes (HP:0001788) | 5.08918704 |
| 3 | Soft skin (HP:0000977) | 3.81776406 |
| 4 | Follicular hyperkeratosis (HP:0007502) | 3.68601722 |
| 5 | Broad metatarsal (HP:0001783) | 3.52715131 |
| 6 | Aortic dissection (HP:0002647) | 3.51176548 |
| 7 | Mesomelia (HP:0003027) | 3.36564522 |
| 8 | Atrophic scars (HP:0001075) | 3.21649786 |
| 9 | Cervical subluxation (HP:0003308) | 3.11455960 |
| 10 | Bell-shaped thorax (HP:0001591) | 3.11105848 |
| 11 | Abnormality of dentin (HP:0010299) | 2.97458701 |
| 12 | Neonatal short-limb short stature (HP:0008921) | 2.96482131 |
| 13 | Syringomyelia (HP:0003396) | 2.95044784 |
| 14 | Spinal cord lesions (HP:0100561) | 2.95044784 |
| 15 | Aortic aneurysm (HP:0004942) | 2.91233203 |
| 16 | Ankle contracture (HP:0006466) | 2.90440784 |
| 17 | Spinal rigidity (HP:0003306) | 2.89936107 |
| 18 | Pulmonary artery stenosis (HP:0004415) | 2.89587055 |
| 19 | White forelock (HP:0002211) | 2.80350289 |
| 20 | Vertebral compression fractures (HP:0002953) | 2.79930387 |
| 21 | Wormian bones (HP:0002645) | 2.77925011 |
| 22 | Mitral valve prolapse (HP:0001634) | 2.74121721 |
| 23 | Blue sclerae (HP:0000592) | 2.72489647 |
| 24 | Bladder diverticulum (HP:0000015) | 2.70170730 |
| 25 | Fragile skin (HP:0001030) | 2.67239111 |
| 26 | Abnormality of incisor morphology (HP:0011063) | 2.65936734 |
| 27 | Patchy hypopigmentation of hair (HP:0011365) | 2.65576202 |
| 28 | Genu recurvatum (HP:0002816) | 2.65023960 |
| 29 | Prostate neoplasm (HP:0100787) | 2.62672681 |
| 30 | Shallow orbits (HP:0000586) | 2.57662874 |
| 31 | Bowel diverticulosis (HP:0005222) | 2.51621412 |
| 32 | Hyperextensible skin (HP:0000974) | 2.48728047 |
| 33 | Vascular tortuosity (HP:0004948) | 2.44374839 |
| 34 | Delayed closure of the anterior fontanelle (HP:0001476) | 2.37789490 |
| 35 | Ulnar bowing (HP:0003031) | 2.33231549 |
| 36 | Congenital sensorineural hearing impairment (HP:0008527) | 2.31050847 |
| 37 | Peritonitis (HP:0002586) | 2.26224414 |
| 38 | Asymmetry of the thorax (HP:0001555) | 2.21130559 |
| 39 | Mild short stature (HP:0003502) | 2.19261721 |
| 40 | Coronal craniosynostosis (HP:0004440) | 2.18156598 |
| 41 | Wide anterior fontanel (HP:0000260) | 2.15544802 |
| 42 | Biconcave vertebral bodies (HP:0004586) | 2.13153586 |
| 43 | Abnormality of the calcaneus (HP:0008364) | 2.11473364 |
| 44 | Decreased skull ossification (HP:0004331) | 2.05052606 |
| 45 | Renal duplication (HP:0000075) | 1.99644095 |
| 46 | Breech presentation (HP:0001623) | 1.98996215 |
| 47 | Abnormal delivery (HP:0001787) | 1.98814700 |
| 48 | Aortic valve stenosis (HP:0001650) | 1.96869467 |
| 49 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.96470648 |
| 50 | Osteolytic defects of the hand bones (HP:0009699) | 1.96470648 |
| 51 | Type 1 muscle fiber predominance (HP:0003803) | 1.96174584 |
| 52 | Nonimmune hydrops fetalis (HP:0001790) | 1.95373970 |
| 53 | Submucous cleft hard palate (HP:0000176) | 1.94413758 |
| 54 | Arterial tortuosity (HP:0005116) | 1.93285580 |
| 55 | Joint laxity (HP:0001388) | 1.92918475 |
| 56 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.91900628 |
| 57 | Coxa vara (HP:0002812) | 1.91638137 |
| 58 | Calcaneovalgus deformity (HP:0001848) | 1.91476200 |
| 59 | Hematochezia (HP:0002573) | 1.90643116 |
| 60 | Aneurysm (HP:0002617) | 1.90106613 |
| 61 | Increased corneal curvature (HP:0100692) | 1.90002135 |
| 62 | Keratoconus (HP:0000563) | 1.90002135 |
| 63 | Abnormality of skull ossification (HP:0002703) | 1.89343992 |
| 64 | Elbow flexion contracture (HP:0002987) | 1.88617402 |
| 65 | Morphological abnormality of the middle ear (HP:0008609) | 1.88352119 |
| 66 | Deformed tarsal bones (HP:0008119) | 1.88340423 |
| 67 | Disproportionate tall stature (HP:0001519) | 1.88195927 |
| 68 | Flared iliac wings (HP:0002869) | 1.88161303 |
| 69 | Natal tooth (HP:0000695) | 1.87196877 |
| 70 | Deviation of the hallux (HP:0010051) | 1.87163611 |
| 71 | Embryonal renal neoplasm (HP:0011794) | 1.87135032 |
| 72 | Cerebral aneurysm (HP:0004944) | 1.86564579 |
| 73 | Ectopia lentis (HP:0001083) | 1.85517056 |
| 74 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.84414928 |
| 75 | Femoral bowing (HP:0002980) | 1.83041067 |
| 76 | Wrist flexion contracture (HP:0001239) | 1.82710371 |
| 77 | Broad ribs (HP:0000885) | 1.82704715 |
| 78 | Hallux valgus (HP:0001822) | 1.82652349 |
| 79 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.82113861 |
| 80 | Inguinal hernia (HP:0000023) | 1.82055781 |
| 81 | Cupped ribs (HP:0000887) | 1.81510602 |
| 82 | Camptodactyly of toe (HP:0001836) | 1.81292326 |
| 83 | Patent foramen ovale (HP:0001655) | 1.80870515 |
| 84 | Subacute progressive viral hepatitis (HP:0006572) | 1.80761123 |
| 85 | Metaphyseal dysplasia (HP:0100255) | 1.80573596 |
| 86 | Abnormality of carpal bone ossification (HP:0006257) | 1.80285496 |
| 87 | Nasolacrimal duct obstruction (HP:0000579) | 1.79669264 |
| 88 | Abnormality of the nasal septum (HP:0000419) | 1.79421067 |
| 89 | Delayed cranial suture closure (HP:0000270) | 1.79416278 |
| 90 | Abnormality of the acetabulum (HP:0003170) | 1.78924447 |
| 91 | Microglossia (HP:0000171) | 1.78168792 |
| 92 | Mitral regurgitation (HP:0001653) | 1.77799047 |
| 93 | Craniofacial hyperostosis (HP:0004493) | 1.77384014 |
| 94 | Dilatation of the ascending aorta (HP:0005111) | 1.76757484 |
| 95 | Infantile muscular hypotonia (HP:0008947) | 1.76416448 |
| 96 | Thoracolumbar scoliosis (HP:0002944) | 1.75795339 |
| 97 | Micromelia (HP:0002983) | 1.75795278 |
| 98 | Flat cornea (HP:0007720) | 1.75427376 |
| 99 | Redundant skin (HP:0001582) | 1.74048828 |
| 100 | Osteoarthritis (HP:0002758) | 1.73388323 |
| 101 | Broad long bones (HP:0005622) | 1.73327395 |
| 102 | Enlarged kidneys (HP:0000105) | 1.72637417 |
| 103 | Rhizomelia (HP:0008905) | 1.72321381 |
| 104 | Hypoplasia of the iris (HP:0007676) | 1.72146785 |
| 105 | Overgrowth (HP:0001548) | 1.71815933 |
| 106 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.71701609 |
| 107 | Aortic regurgitation (HP:0001659) | 1.71378296 |
| 108 | Abnormality of the nasolacrimal system (HP:0000614) | 1.71370778 |
| 109 | Knee flexion contracture (HP:0006380) | 1.71233267 |
| 110 | Hyperacusis (HP:0010780) | 1.71067328 |
| 111 | Systemic lupus erythematosus (HP:0002725) | 1.70647985 |
| 112 | Abnormality of the lumbar spine (HP:0100712) | 1.69315645 |
| 113 | Slender build (HP:0001533) | 1.67981963 |
| 114 | Joint contractures involving the joints of the feet (HP:0100492) | 1.67854285 |
| 115 | Flexion contracture of toe (HP:0005830) | 1.67854285 |
| 116 | Synostosis involving bones of the lower limbs (HP:0009138) | 1.67473523 |
| 117 | Synostosis involving bones of the feet (HP:0009140) | 1.67473523 |
| 118 | Distal lower limb muscle weakness (HP:0009053) | 1.67467581 |
| 119 | Abnormality of the umbilical cord (HP:0010881) | 1.66871768 |
| 120 | Chromsome breakage (HP:0040012) | 1.66288694 |
| 121 | Disproportionate short-trunk short stature (HP:0003521) | 1.65827750 |
| 122 | Osteomalacia (HP:0002749) | 1.65747766 |
| 123 | Hypothermia (HP:0002045) | 1.65176352 |
| 124 | Cardiovascular calcification (HP:0011915) | 1.65175685 |
| 125 | Absent frontal sinuses (HP:0002688) | 1.63736960 |
| 126 | Spondylolisthesis (HP:0003302) | 1.62666381 |
| 127 | Tarsal synostosis (HP:0008368) | 1.62362118 |
| 128 | Short middle phalanx of the 5th finger (HP:0004220) | 1.61860077 |
| 129 | Short nail (HP:0001799) | 1.61633797 |
| 130 | Platyspondyly (HP:0000926) | 1.61484990 |
| 131 | Protruding ear (HP:0000411) | 1.61386140 |
| 132 | Hypoplastic left heart (HP:0004383) | 1.60854668 |
| 133 | Abnormal ossification of hand bones (HP:0005921) | 1.60568419 |
| 134 | Generalized amyotrophy (HP:0003700) | 1.59934095 |
| 135 | Trismus (HP:0000211) | 1.59846038 |
| 136 | Spontaneous hematomas (HP:0007420) | 1.58384765 |
| 137 | Persistence of primary teeth (HP:0006335) | 1.58261663 |
| 138 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.58165843 |
| 139 | Selective tooth agenesis (HP:0001592) | 1.58157797 |
| 140 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.55207528 |
| 141 | Single umbilical artery (HP:0001195) | 1.55207528 |
| 142 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.55207528 |
| 143 | Mitral stenosis (HP:0001718) | 1.55203729 |
| 144 | Venous abnormality (HP:0002624) | 1.52985085 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 4.17991558 |
| 2 | NEK9 | 2.95041644 |
| 3 | ZAK | 2.92761472 |
| 4 | TGFBR2 | 2.64891087 |
| 5 | TIE1 | 2.64495828 |
| 6 | NUAK1 | 2.64320261 |
| 7 | MST1R | 2.43338618 |
| 8 | BMPR1B | 2.38773721 |
| 9 | DDR2 | 2.37693262 |
| 10 | WEE1 | 2.35746460 |
| 11 | CDK8 | 2.19081714 |
| 12 | TGFBR1 | 2.18483925 |
| 13 | STK38L | 2.08545774 |
| 14 | PTK2 | 2.02716149 |
| 15 | EPHB2 | 1.99366957 |
| 16 | BLK | 1.98131065 |
| 17 | TRPM7 | 1.96050414 |
| 18 | PAK4 | 1.85501899 |
| 19 | IRAK3 | 1.82438159 |
| 20 | CASK | 1.78627385 |
| 21 | LIMK1 | 1.77810265 |
| 22 | EPHA3 | 1.73512232 |
| 23 | ERBB4 | 1.72109254 |
| 24 | LATS1 | 1.70452769 |
| 25 | EIF2AK2 | 1.68997619 |
| 26 | STK16 | 1.65906274 |
| 27 | BUB1 | 1.64901381 |
| 28 | TTK | 1.62510318 |
| 29 | PIM2 | 1.61717261 |
| 30 | MYLK | 1.61097189 |
| 31 | TRIB3 | 1.60100754 |
| 32 | SCYL2 | 1.55142785 |
| 33 | MAP3K14 | 1.55001666 |
| 34 | PDGFRA | 1.49781811 |
| 35 | ERBB3 | 1.49092812 |
| 36 | ICK | 1.47912975 |
| 37 | MKNK1 | 1.47039131 |
| 38 | EIF2AK1 | 1.44856129 |
| 39 | NEK2 | 1.44102603 |
| 40 | TESK1 | 1.41665527 |
| 41 | SIK3 | 1.41388153 |
| 42 | NEK1 | 1.41259313 |
| 43 | SMG1 | 1.40373383 |
| 44 | IRAK4 | 1.38705185 |
| 45 | BRSK2 | 1.33208963 |
| 46 | YES1 | 1.28922496 |
| 47 | NME2 | 1.27482419 |
| 48 | NEK6 | 1.23778670 |
| 49 | RIPK1 | 1.18850396 |
| 50 | MKNK2 | 1.18784768 |
| 51 | TEC | 1.18574265 |
| 52 | VRK2 | 1.17281187 |
| 53 | CDK12 | 1.16768345 |
| 54 | FGFR2 | 1.16156461 |
| 55 | LATS2 | 1.15533454 |
| 56 | MOS | 1.15465140 |
| 57 | PIK3CG | 1.14432406 |
| 58 | STK38 | 1.13904164 |
| 59 | EEF2K | 1.13855970 |
| 60 | CDC7 | 1.13496255 |
| 61 | NTRK1 | 1.06689341 |
| 62 | DMPK | 1.05449814 |
| 63 | MELK | 1.02922252 |
| 64 | TAF1 | 0.99715384 |
| 65 | PIK3CA | 0.94134179 |
| 66 | AKT3 | 0.93342673 |
| 67 | INSRR | 0.93152447 |
| 68 | TXK | 0.92689683 |
| 69 | PRKCE | 0.91497577 |
| 70 | STK3 | 0.91138773 |
| 71 | CHEK2 | 0.90072353 |
| 72 | BMPR2 | 0.89318250 |
| 73 | BRSK1 | 0.87556712 |
| 74 | CDK3 | 0.85983297 |
| 75 | PTK2B | 0.85376793 |
| 76 | FGFR1 | 0.84806668 |
| 77 | VRK1 | 0.84684415 |
| 78 | PLK4 | 0.84287522 |
| 79 | AURKB | 0.83914699 |
| 80 | PNCK | 0.82985420 |
| 81 | PLK2 | 0.82013672 |
| 82 | SRPK1 | 0.81198365 |
| 83 | TTN | 0.81083918 |
| 84 | CDK6 | 0.80589910 |
| 85 | PDGFRB | 0.79717794 |
| 86 | ROCK1 | 0.79649328 |
| 87 | FGFR4 | 0.79146745 |
| 88 | IRAK1 | 0.78813814 |
| 89 | RPS6KA4 | 0.78362353 |
| 90 | ILK | 0.77921691 |
| 91 | PAK2 | 0.76466972 |
| 92 | MTOR | 0.75811617 |
| 93 | MAP3K8 | 0.75318417 |
| 94 | MAPK7 | 0.74086180 |
| 95 | FER | 0.73731888 |
| 96 | PKN2 | 0.72872616 |
| 97 | PLK3 | 0.71215593 |
| 98 | JAK3 | 0.70255812 |
| 99 | CHUK | 0.69171668 |
| 100 | IKBKB | 0.68241376 |
| 101 | PLK1 | 0.68117964 |
| 102 | PDK2 | 0.66168818 |
| 103 | GRK1 | 0.65479813 |
| 104 | TSSK6 | 0.61835505 |
| 105 | CHEK1 | 0.60675723 |
| 106 | ERN1 | 0.59946681 |
| 107 | MET | 0.59691339 |
| 108 | KIT | 0.59468317 |
| 109 | BCR | 0.58965820 |
| 110 | GSK3A | 0.58682686 |
| 111 | ADRBK2 | 0.58073031 |
| 112 | STK10 | 0.58015433 |
| 113 | PRKD2 | 0.57875231 |
| 114 | RPS6KC1 | 0.54545200 |
| 115 | RPS6KL1 | 0.54545200 |
| 116 | MAPK13 | 0.54028239 |
| 117 | ABL2 | 0.51962369 |
| 118 | GRK7 | 0.51715409 |
| 119 | MAPK15 | 0.50235402 |
| 120 | JAK1 | 0.48265639 |
| 121 | MAP3K3 | 0.48018239 |
| 122 | FLT3 | 0.47436315 |
| 123 | PIM1 | 0.46246019 |
| 124 | RPS6KA6 | 0.45840770 |
| 125 | EIF2AK3 | 0.44918713 |
| 126 | CSNK1A1L | 0.44758631 |
| 127 | ATR | 0.44274638 |
| 128 | MAP2K1 | 0.43910132 |
| 129 | MATK | 0.43705854 |
| 130 | PBK | 0.43491980 |
| 131 | PTK6 | 0.42441321 |
| 132 | ROCK2 | 0.42440654 |
| 133 | MAPK11 | 0.42199850 |
| 134 | FGFR3 | 0.41993999 |
| 135 | CDC42BPA | 0.41654664 |
| 136 | SGK2 | 0.41145221 |
| 137 | SIK1 | 0.41120294 |
| 138 | KDR | 0.40852805 |
| 139 | PRKG2 | 0.40738476 |
| 140 | IKBKE | 0.40509687 |
| 141 | CDK7 | 0.40411799 |
| 142 | MAP2K2 | 0.39105098 |
| 143 | STK4 | 0.38657521 |
| 144 | NLK | 0.37993891 |
| 145 | CDK4 | 0.37569029 |
| 146 | INSR | 0.37522066 |
| 147 | ABL1 | 0.36543587 |
| 148 | MARK3 | 0.36535404 |
| 149 | CSF1R | 0.36369915 |
| 150 | IGF1R | 0.36318278 |
| 151 | EPHA2 | 0.36195165 |
| 152 | CAMK1D | 0.35910009 |
| 153 | MUSK | 0.35749039 |
| 154 | RPS6KB2 | 0.35559295 |
| 155 | RPS6KA2 | 0.35529870 |
| 156 | ATM | 0.34957629 |
| 157 | CLK1 | 0.33610922 |
| 158 | MAP3K12 | 0.32676750 |
| 159 | PAK1 | 0.31492781 |
| 160 | CDK9 | 0.31096179 |
| 161 | CDK18 | 0.30225663 |
| 162 | BRD4 | 0.30042983 |
| 163 | CSNK1G1 | 0.29387546 |
| 164 | LYN | 0.28958920 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 3.59151806 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 2.69804031 |
| 3 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.64630180 |
| 4 | Malaria_Homo sapiens_hsa05144 | 2.24842579 |
| 5 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.14352984 |
| 6 | Protein digestion and absorption_Homo sapiens_hsa04974 | 2.13277636 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.12871104 |
| 8 | Focal adhesion_Homo sapiens_hsa04510 | 2.11406843 |
| 9 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 2.06556749 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 1.97687614 |
| 11 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.97283437 |
| 12 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.95520653 |
| 13 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.94208025 |
| 14 | Other glycan degradation_Homo sapiens_hsa00511 | 1.93725455 |
| 15 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.77398223 |
| 16 | Adherens junction_Homo sapiens_hsa04520 | 1.71319379 |
| 17 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.67377664 |
| 18 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.65540215 |
| 19 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.58159159 |
| 20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.58130892 |
| 21 | Bladder cancer_Homo sapiens_hsa05219 | 1.56149211 |
| 22 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.50258172 |
| 23 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.44762920 |
| 24 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.42890643 |
| 25 | Amoebiasis_Homo sapiens_hsa05146 | 1.42765196 |
| 26 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.41399883 |
| 27 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.40040473 |
| 28 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.39556596 |
| 29 | Thyroid cancer_Homo sapiens_hsa05216 | 1.35155502 |
| 30 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.34969363 |
| 31 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.30841429 |
| 32 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.28969531 |
| 33 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.24681351 |
| 34 | Melanoma_Homo sapiens_hsa05218 | 1.22434812 |
| 35 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.21378712 |
| 36 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.21377459 |
| 37 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.20818140 |
| 38 | Viral myocarditis_Homo sapiens_hsa05416 | 1.20420598 |
| 39 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.20248801 |
| 40 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.19965544 |
| 41 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.16849003 |
| 42 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.16607128 |
| 43 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.13993908 |
| 44 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.12098952 |
| 45 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.11225262 |
| 46 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.10812072 |
| 47 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.09921098 |
| 48 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.08031447 |
| 49 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.07010358 |
| 50 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.04774540 |
| 51 | Pathways in cancer_Homo sapiens_hsa05200 | 1.04242201 |
| 52 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.01526192 |
| 53 | Prostate cancer_Homo sapiens_hsa05215 | 0.99938266 |
| 54 | Phagosome_Homo sapiens_hsa04145 | 0.99672206 |
| 55 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.98783760 |
| 56 | Retinol metabolism_Homo sapiens_hsa00830 | 0.98588666 |
| 57 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.96201980 |
| 58 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.95710870 |
| 59 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.94633522 |
| 60 | RNA transport_Homo sapiens_hsa03013 | 0.93612766 |
| 61 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.92934039 |
| 62 | Measles_Homo sapiens_hsa05162 | 0.91112392 |
| 63 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.90574948 |
| 64 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90217856 |
| 65 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.89810644 |
| 66 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.89772374 |
| 67 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.89447262 |
| 68 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.87436664 |
| 69 | Leishmaniasis_Homo sapiens_hsa05140 | 0.86986533 |
| 70 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.86533098 |
| 71 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.86422306 |
| 72 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.85984923 |
| 73 | Homologous recombination_Homo sapiens_hsa03440 | 0.85789176 |
| 74 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.82731286 |
| 75 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.82059981 |
| 76 | RNA degradation_Homo sapiens_hsa03018 | 0.81591146 |
| 77 | Base excision repair_Homo sapiens_hsa03410 | 0.81382521 |
| 78 | Colorectal cancer_Homo sapiens_hsa05210 | 0.81301999 |
| 79 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.79721299 |
| 80 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.79444093 |
| 81 | Tight junction_Homo sapiens_hsa04530 | 0.79317182 |
| 82 | Lysine degradation_Homo sapiens_hsa00310 | 0.79220429 |
| 83 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.77907594 |
| 84 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.77817858 |
| 85 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.77498527 |
| 86 | Platelet activation_Homo sapiens_hsa04611 | 0.77329163 |
| 87 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.77268796 |
| 88 | Melanogenesis_Homo sapiens_hsa04916 | 0.74027943 |
| 89 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.73162388 |
| 90 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.73140750 |
| 91 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.73108783 |
| 92 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.73041209 |
| 93 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.71552893 |
| 94 | Endometrial cancer_Homo sapiens_hsa05213 | 0.71327634 |
| 95 | HTLV-I infection_Homo sapiens_hsa05166 | 0.70671214 |
| 96 | Glioma_Homo sapiens_hsa05214 | 0.70302983 |
| 97 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.69579965 |
| 98 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.68351680 |
| 99 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.67871132 |
| 100 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67061363 |
| 101 | Lysosome_Homo sapiens_hsa04142 | 0.67027066 |
| 102 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.66738524 |
| 103 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.66578907 |
| 104 | Allograft rejection_Homo sapiens_hsa05330 | 0.65609263 |
| 105 | Cell cycle_Homo sapiens_hsa04110 | 0.65154931 |
| 106 | Apoptosis_Homo sapiens_hsa04210 | 0.63372153 |
| 107 | Pertussis_Homo sapiens_hsa05133 | 0.63335172 |
| 108 | Prion diseases_Homo sapiens_hsa05020 | 0.62761466 |
| 109 | Basal transcription factors_Homo sapiens_hsa03022 | 0.61921793 |
| 110 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.61665130 |
| 111 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.61646791 |
| 112 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.61434714 |
| 113 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.61370326 |
| 114 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.61118127 |
| 115 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.60166265 |
| 116 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.60017416 |
| 117 | Carbon metabolism_Homo sapiens_hsa01200 | 0.59458649 |
| 118 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.58431455 |
| 119 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.57960178 |
| 120 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.57871328 |
| 121 | Axon guidance_Homo sapiens_hsa04360 | 0.56475859 |
| 122 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.56220446 |
| 123 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.55912191 |
| 124 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.55303596 |
| 125 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.54795861 |
| 126 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.54678668 |
| 127 | Hepatitis B_Homo sapiens_hsa05161 | 0.54347596 |
| 128 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.53587337 |
| 129 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.52906363 |
| 130 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51494337 |
| 131 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51369981 |
| 132 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.51314914 |
| 133 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.51256157 |
| 134 | Galactose metabolism_Homo sapiens_hsa00052 | 0.51093169 |
| 135 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.50954373 |
| 136 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50259880 |
| 137 | Shigellosis_Homo sapiens_hsa05131 | 0.49545373 |
| 138 | Sulfur relay system_Homo sapiens_hsa04122 | 0.48732799 |
| 139 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.48273586 |
| 140 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.47680118 |
| 141 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.47398047 |
| 142 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.46112573 |
| 143 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.45351077 |
| 144 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.42771512 |
| 145 | Spliceosome_Homo sapiens_hsa03040 | 0.41122458 |
| 146 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.39255662 |
| 147 | Gap junction_Homo sapiens_hsa04540 | 0.38710923 |
| 148 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.36378855 |
| 149 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.34338896 |
| 150 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.32768578 |

