Rank | Gene Set | Z-score |
---|---|---|
1 | cytoplasmic mRNA processing body assembly (GO:0033962) | 4.40192554 |
2 | negative regulation of erythrocyte differentiation (GO:0045647) | 4.17891135 |
3 | histone H3-K4 trimethylation (GO:0080182) | 4.00768103 |
4 | mitotic sister chromatid cohesion (GO:0007064) | 3.91666962 |
5 | response to muramyl dipeptide (GO:0032495) | 3.80518207 |
6 | pre-miRNA processing (GO:0031054) | 3.77213611 |
7 | positive regulation of histone deacetylation (GO:0031065) | 3.75846019 |
8 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.72596056 |
9 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.72596056 |
10 | modulation by symbiont of host immune response (GO:0052553) | 3.72596056 |
11 | positive regulation by symbiont of host defense response (GO:0052509) | 3.72596056 |
12 | modulation by symbiont of host defense response (GO:0052031) | 3.72596056 |
13 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.72596056 |
14 | nuclear pore complex assembly (GO:0051292) | 3.67694292 |
15 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.65677109 |
16 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.59267621 |
17 | detection of other organism (GO:0098543) | 3.50824602 |
18 | detection of bacterium (GO:0016045) | 3.44766511 |
19 | macrophage activation involved in immune response (GO:0002281) | 3.41857691 |
20 | leukocyte aggregation (GO:0070486) | 3.36335747 |
21 | mannose metabolic process (GO:0006013) | 3.35676847 |
22 | histone H3-K4 methylation (GO:0051568) | 3.33254965 |
23 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.32676184 |
24 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.25587821 |
25 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.25587821 |
26 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.25587821 |
27 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.22600483 |
28 | regulation of histone H3-K27 methylation (GO:0061085) | 3.21687530 |
29 | germinal center formation (GO:0002467) | 3.19111350 |
30 | positive thymic T cell selection (GO:0045059) | 3.19065540 |
31 | tolerance induction (GO:0002507) | 3.14902676 |
32 | response to peptidoglycan (GO:0032494) | 3.14170601 |
33 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.07157496 |
34 | nuclear pore organization (GO:0006999) | 3.06798629 |
35 | histone H3-K9 demethylation (GO:0033169) | 3.03258796 |
36 | growth hormone receptor signaling pathway (GO:0060396) | 3.02552488 |
37 | peptidyl-lysine trimethylation (GO:0018023) | 3.01801675 |
38 | regulation of gamma-delta T cell activation (GO:0046643) | 2.97657313 |
39 | negative regulation of T cell mediated immunity (GO:0002710) | 2.97060389 |
40 | cellular extravasation (GO:0045123) | 2.96379854 |
41 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.95775260 |
42 | response to laminar fluid shear stress (GO:0034616) | 2.95610972 |
43 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.95019016 |
44 | response to interleukin-15 (GO:0070672) | 2.94217461 |
45 | response to type I interferon (GO:0034340) | 2.93283383 |
46 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.91997963 |
47 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.91294145 |
48 | detection of external biotic stimulus (GO:0098581) | 2.90232360 |
49 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.88717936 |
50 | cellular response to type I interferon (GO:0071357) | 2.88483584 |
51 | type I interferon signaling pathway (GO:0060337) | 2.88483584 |
52 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.85938463 |
53 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.85938463 |
54 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.82603600 |
55 | embryonic camera-type eye morphogenesis (GO:0048596) | 2.81891453 |
56 | pore complex assembly (GO:0046931) | 2.80696640 |
57 | NLS-bearing protein import into nucleus (GO:0006607) | 2.80283814 |
58 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.78008106 |
59 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.77997492 |
60 | histone lysine methylation (GO:0034968) | 2.77616441 |
61 | positive T cell selection (GO:0043368) | 2.77154408 |
62 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.76241770 |
63 | thymic T cell selection (GO:0045061) | 2.74892003 |
64 | embryonic process involved in female pregnancy (GO:0060136) | 2.74826907 |
65 | negative T cell selection (GO:0043383) | 2.74236517 |
66 | T cell migration (GO:0072678) | 2.73320261 |
67 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.72678881 |
68 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.71673368 |
69 | negative thymic T cell selection (GO:0045060) | 2.71235458 |
70 | negative regulation of histone methylation (GO:0031061) | 2.71108371 |
71 | NIK/NF-kappaB signaling (GO:0038061) | 2.69695375 |
72 | negative regulation of granulocyte differentiation (GO:0030853) | 2.69625890 |
73 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.69622983 |
74 | positive regulation of mRNA catabolic process (GO:0061014) | 2.68207298 |
75 | cellular response to growth hormone stimulus (GO:0071378) | 2.67705999 |
76 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.66985319 |
77 | regulation of RNA export from nucleus (GO:0046831) | 2.64488871 |
78 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.63964330 |
79 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.63964330 |
80 | definitive hemopoiesis (GO:0060216) | 2.63384749 |
81 | detection of molecule of bacterial origin (GO:0032490) | 2.62979089 |
82 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.61690342 |
83 | regulation of necroptotic process (GO:0060544) | 2.60981282 |
84 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.60830159 |
85 | positive regulation of Rap GTPase activity (GO:0032854) | 2.60201739 |
86 | regulation of ARF protein signal transduction (GO:0032012) | 2.59997750 |
87 | negative regulation of interleukin-12 production (GO:0032695) | 2.59477308 |
88 | neutrophil activation involved in immune response (GO:0002283) | 2.59344197 |
89 | T cell selection (GO:0045058) | 2.59144883 |
90 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.58716895 |
91 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.58716895 |
92 | regulation of DNA endoreduplication (GO:0032875) | 2.58390478 |
93 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.57940164 |
94 | response to host (GO:0075136) | 2.57940164 |
95 | response to host defenses (GO:0052200) | 2.57940164 |
96 | regulation of T cell tolerance induction (GO:0002664) | 2.57198293 |
97 | mRNA stabilization (GO:0048255) | 2.57049604 |
98 | RNA stabilization (GO:0043489) | 2.57049604 |
99 | detection of biotic stimulus (GO:0009595) | 2.56879728 |
100 | positive regulation of granulocyte differentiation (GO:0030854) | 2.56859535 |
101 | B cell homeostasis (GO:0001782) | 2.56617205 |
102 | regulation of mRNA catabolic process (GO:0061013) | 2.56180814 |
103 | germ cell migration (GO:0008354) | 2.55829828 |
104 | regulation of B cell differentiation (GO:0045577) | 2.55274844 |
105 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.55166028 |
106 | corticosteroid receptor signaling pathway (GO:0031958) | 2.54464751 |
107 | regulation of tolerance induction (GO:0002643) | 2.53785895 |
108 | positive regulation of protein deacetylation (GO:0090312) | 2.53481483 |
109 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.53223053 |
110 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.53057033 |
111 | positive regulation of B cell differentiation (GO:0045579) | 2.51857102 |
112 | * histone H3-K36 demethylation (GO:0070544) | 2.51252608 |
113 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.49585143 |
114 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.49294652 |
115 | regulation of histone deacetylation (GO:0031063) | 2.47529595 |
116 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.47178120 |
117 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.45999808 |
118 | response to host immune response (GO:0052572) | 2.45999808 |
119 | regulation of leukocyte degranulation (GO:0043300) | 2.43305187 |
120 | defense response to protozoan (GO:0042832) | 2.43127188 |
121 | histone H3-K9 methylation (GO:0051567) | 2.41823594 |
122 | histone H3-K9 modification (GO:0061647) | 2.41224384 |
123 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.39828880 |
124 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.39595830 |
125 | cellular response to interleukin-15 (GO:0071350) | 2.39186464 |
126 | peptidyl-lysine methylation (GO:0018022) | 2.38923761 |
127 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.38440069 |
128 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.37771892 |
129 | positive regulation of tolerance induction (GO:0002645) | 2.36409872 |
130 | signal complex assembly (GO:0007172) | 2.36270092 |
131 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.36246573 |
132 | cellular response to virus (GO:0098586) | 2.34447911 |
133 | regulation of protein polyubiquitination (GO:1902914) | 2.34117681 |
134 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.33279915 |
135 | response to protozoan (GO:0001562) | 2.33271442 |
136 | * histone lysine demethylation (GO:0070076) | 2.31969786 |
137 | B cell receptor signaling pathway (GO:0050853) | 2.31822727 |
138 | peptidyl-lysine dimethylation (GO:0018027) | 2.31517055 |
139 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.30949599 |
140 | macrophage activation (GO:0042116) | 2.30431874 |
141 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.30298889 |
142 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.28087420 |
143 | embryonic eye morphogenesis (GO:0048048) | 2.27651631 |
144 | heart morphogenesis (GO:0003007) | 2.25321607 |
145 | interkinetic nuclear migration (GO:0022027) | 2.20363712 |
146 | * histone demethylation (GO:0016577) | 2.20100432 |
147 | embryonic hemopoiesis (GO:0035162) | 2.19872495 |
148 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.19220380 |
149 | hepatocyte apoptotic process (GO:0097284) | 2.18747061 |
150 | coronary vasculature morphogenesis (GO:0060977) | 2.15999841 |
151 | histone mRNA catabolic process (GO:0071044) | 2.13635873 |
152 | regulation of histone H3-K9 methylation (GO:0051570) | 2.13128728 |
153 | regulation of protein deacetylation (GO:0090311) | 2.09849621 |
154 | hippo signaling (GO:0035329) | 2.09551556 |
155 | histone H4-K16 acetylation (GO:0043984) | 2.09314576 |
156 | stress granule assembly (GO:0034063) | 2.09156636 |
157 | negative regulation of stress fiber assembly (GO:0051497) | 2.08297136 |
158 | negative regulation of cell killing (GO:0031342) | 2.08209296 |
159 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.08209296 |
160 | cell-substrate junction assembly (GO:0007044) | 2.06277761 |
161 | regulation of histone methylation (GO:0031060) | 2.05023511 |
162 | histone methylation (GO:0016571) | 2.03561420 |
163 | fibroblast migration (GO:0010761) | 2.03302738 |
164 | megakaryocyte development (GO:0035855) | 2.01190619 |
165 | negative regulation of phagocytosis (GO:0050765) | 1.99877987 |
166 | positive regulation of hormone biosynthetic process (GO:0046886) | 1.99758561 |
167 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 1.98787618 |
168 | negative regulation of fatty acid transport (GO:2000192) | 1.98638258 |
169 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 1.98444382 |
170 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 1.98444382 |
171 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 1.98444382 |
172 | hemidesmosome assembly (GO:0031581) | 1.98317948 |
173 | regulation of mRNA stability (GO:0043488) | 1.98154997 |
174 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 1.98144157 |
175 | regulation of B cell receptor signaling pathway (GO:0050855) | 1.97969810 |
176 | face morphogenesis (GO:0060325) | 1.96886622 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 4.53094824 |
2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.12527866 |
3 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.79374965 |
4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.70974547 |
5 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.83822834 |
6 | MYC_22102868_ChIP-Seq_BL_Human | 2.74852957 |
7 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.52082139 |
8 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.38396195 |
9 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.34198099 |
10 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.33020462 |
11 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.28805170 |
12 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.16942666 |
13 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.15897513 |
14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.14561971 |
15 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.14214330 |
16 | * KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.08431079 |
17 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.05403174 |
18 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.99551552 |
19 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.93046867 |
20 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.90545020 |
21 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.89443762 |
22 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.84336302 |
23 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.77492502 |
24 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.77369237 |
25 | * MAF_26560356_Chip-Seq_TH2_Human | 1.76585023 |
26 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.74427440 |
27 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.73892231 |
28 | MAF_26560356_Chip-Seq_TH1_Human | 1.71715247 |
29 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.70193196 |
30 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.68740880 |
31 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.67090060 |
32 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.66084138 |
33 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.64492122 |
34 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.64443632 |
35 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.63965257 |
36 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.61144369 |
37 | MYB_26560356_Chip-Seq_TH1_Human | 1.60915171 |
38 | UTX_26944678_Chip-Seq_JUKART_Human | 1.59125591 |
39 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.58671196 |
40 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.58637789 |
41 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.58420396 |
42 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.56205281 |
43 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.56141949 |
44 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.55277434 |
45 | MYB_26560356_Chip-Seq_TH2_Human | 1.55233106 |
46 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.54863168 |
47 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.52095729 |
48 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.50914728 |
49 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.50547021 |
50 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.47953069 |
51 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.47941398 |
52 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.47486884 |
53 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.46693731 |
54 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.45607573 |
55 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.44639421 |
56 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40376722 |
57 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.39962215 |
58 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.39501682 |
59 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.38251405 |
60 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.37928568 |
61 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.36986144 |
62 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.35779170 |
63 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.35714417 |
64 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.35411046 |
65 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.34793941 |
66 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.34694504 |
67 | TP53_16413492_ChIP-PET_HCT116_Human | 1.34565766 |
68 | * ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.33625931 |
69 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.32935615 |
70 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.30085478 |
71 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.29838600 |
72 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.28946560 |
73 | SPI1_23127762_ChIP-Seq_K562_Human | 1.27693491 |
74 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.26033514 |
75 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.25462603 |
76 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.25238736 |
77 | GATA1_22025678_ChIP-Seq_K562_Human | 1.25219501 |
78 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.24466117 |
79 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.22817378 |
80 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.22808889 |
81 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.22017037 |
82 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.20784388 |
83 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.20704590 |
84 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.16209707 |
85 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.16209707 |
86 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.14692377 |
87 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.14675500 |
88 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.14618067 |
89 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.14583654 |
90 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.14316777 |
91 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.14254431 |
92 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.13435260 |
93 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.13302141 |
94 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.12994406 |
95 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.12721455 |
96 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.12452761 |
97 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.12428282 |
98 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.12180806 |
99 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.11899486 |
100 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.11230128 |
101 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.11018688 |
102 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.10852878 |
103 | KDM2B_26808549_Chip-Seq_K562_Human | 1.10822182 |
104 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.10398845 |
105 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.10339968 |
106 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.09232870 |
107 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09143862 |
108 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.08581643 |
109 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.08578404 |
110 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.08557601 |
111 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.07516992 |
112 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.07058156 |
113 | * PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.07030198 |
114 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.06609560 |
115 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.06160441 |
116 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.05628548 |
117 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.05319066 |
118 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.04680848 |
119 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.03648779 |
120 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.03080283 |
121 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.02894052 |
122 | * SMC4_20622854_ChIP-Seq_HELA_Human | 1.02618582 |
123 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.01943006 |
124 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.01279210 |
125 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.01214515 |
126 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.00351177 |
127 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.99460194 |
128 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.98777033 |
129 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.98483142 |
130 | GATA1_19941826_ChIP-Seq_K562_Human | 0.98039941 |
131 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.97490608 |
132 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.96682119 |
133 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.95458227 |
134 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.94079918 |
135 | * PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.92427832 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000569_abnormal_digit_pigmentation | 3.47425694 |
2 | MP0003300_gastrointestinal_ulcer | 2.97005188 |
3 | MP0010352_gastrointestinal_tract_polyps | 2.79197170 |
4 | MP0005076_abnormal_cell_differentiation | 2.71881970 |
5 | MP0002166_altered_tumor_susceptibility | 2.55459218 |
6 | MP0005451_abnormal_body_composition | 2.44784052 |
7 | MP0003724_increased_susceptibility_to | 2.37741806 |
8 | MP0004808_abnormal_hematopoietic_stem | 2.31655750 |
9 | MP0003705_abnormal_hypodermis_morpholog | 2.27495584 |
10 | MP0005000_abnormal_immune_tolerance | 2.18770494 |
11 | MP0008260_abnormal_autophagy | 2.06547849 |
12 | MP0005025_abnormal_response_to | 2.04408988 |
13 | MP0002419_abnormal_innate_immunity | 2.03788058 |
14 | MP0002009_preneoplasia | 2.02005519 |
15 | MP0003045_fibrosis | 1.99837853 |
16 | MP0009278_abnormal_bone_marrow | 1.96203941 |
17 | MP0002006_tumorigenesis | 1.89413980 |
18 | MP0004381_abnormal_hair_follicle | 1.84309879 |
19 | MP0003191_abnormal_cellular_cholesterol | 1.84076279 |
20 | MP0002877_abnormal_melanocyte_morpholog | 1.83727486 |
21 | MP0002396_abnormal_hematopoietic_system | 1.82025030 |
22 | MP0003566_abnormal_cell_adhesion | 1.79276808 |
23 | MP0003172_abnormal_lysosome_physiology | 1.77357069 |
24 | MP0009333_abnormal_splenocyte_physiolog | 1.70442436 |
25 | MP0008438_abnormal_cutaneous_collagen | 1.69827364 |
26 | MP0000733_abnormal_muscle_development | 1.65991040 |
27 | MP0008961_abnormal_basal_metabolism | 1.65849822 |
28 | MP0001790_abnormal_immune_system | 1.62942905 |
29 | MP0005387_immune_system_phenotype | 1.62942905 |
30 | MP0003787_abnormal_imprinting | 1.61538546 |
31 | MP0010234_abnormal_vibrissa_follicle | 1.59329529 |
32 | MP0001835_abnormal_antigen_presentation | 1.59318773 |
33 | MP0005310_abnormal_salivary_gland | 1.59037101 |
34 | MP0003763_abnormal_thymus_physiology | 1.55958172 |
35 | MP0003303_peritoneal_inflammation | 1.55134785 |
36 | MP0010307_abnormal_tumor_latency | 1.54973635 |
37 | MP0001800_abnormal_humoral_immune | 1.54101563 |
38 | MP0000685_abnormal_immune_system | 1.52057939 |
39 | MP0001533_abnormal_skeleton_physiology | 1.49219220 |
40 | MP0009785_altered_susceptibility_to | 1.48179614 |
41 | MP0005409_darkened_coat_color | 1.47980580 |
42 | MP0001851_eye_inflammation | 1.44302534 |
43 | MP0003091_abnormal_cell_migration | 1.41465858 |
44 | MP0000858_altered_metastatic_potential | 1.40050203 |
45 | MP0002796_impaired_skin_barrier | 1.37251683 |
46 | MP0003866_abnormal_defecation | 1.35652988 |
47 | MP0004185_abnormal_adipocyte_glucose | 1.34453017 |
48 | MP0005248_abnormal_Harderian_gland | 1.33872006 |
49 | MP0004264_abnormal_extraembryonic_tissu | 1.32243254 |
50 | MP0005464_abnormal_platelet_physiology | 1.31875726 |
51 | MP0005503_abnormal_tendon_morphology | 1.31659400 |
52 | MP0000703_abnormal_thymus_morphology | 1.29020878 |
53 | MP0005023_abnormal_wound_healing | 1.28879301 |
54 | MP0005275_abnormal_skin_tensile | 1.25515311 |
55 | MP0001348_abnormal_lacrimal_gland | 1.25412577 |
56 | MP0002398_abnormal_bone_marrow | 1.25350263 |
57 | MP0004197_abnormal_fetal_growth/weight/ | 1.23071861 |
58 | MP0002060_abnormal_skin_morphology | 1.21567261 |
59 | MP0009703_decreased_birth_body | 1.21564758 |
60 | MP0005058_abnormal_lysosome_morphology | 1.21561302 |
61 | MP0001845_abnormal_inflammatory_respons | 1.20974907 |
62 | MP0002452_abnormal_antigen_presenting | 1.20159142 |
63 | MP0002148_abnormal_hypersensitivity_rea | 1.19964639 |
64 | MP0001873_stomach_inflammation | 1.19629740 |
65 | MP0000767_abnormal_smooth_muscle | 1.18497923 |
66 | MP0001545_abnormal_hematopoietic_system | 1.17122487 |
67 | MP0005397_hematopoietic_system_phenotyp | 1.17122487 |
68 | MP0005671_abnormal_response_to | 1.17097346 |
69 | MP0003935_abnormal_craniofacial_develop | 1.16625989 |
70 | MP0010155_abnormal_intestine_physiology | 1.16162761 |
71 | MP0006082_CNS_inflammation | 1.15988753 |
72 | MP0003252_abnormal_bile_duct | 1.12679535 |
73 | MP0002925_abnormal_cardiovascular_devel | 1.12242705 |
74 | MP0003828_pulmonary_edema | 1.11528369 |
75 | MP0004947_skin_inflammation | 1.11195110 |
76 | MP0010678_abnormal_skin_adnexa | 1.10215686 |
77 | MP0001853_heart_inflammation | 1.09162515 |
78 | MP0000428_abnormal_craniofacial_morphol | 1.08376981 |
79 | MP0005666_abnormal_adipose_tissue | 1.08319936 |
80 | MP0000383_abnormal_hair_follicle | 1.08186760 |
81 | MP0000465_gastrointestinal_hemorrhage | 1.06939671 |
82 | MP0001849_ear_inflammation | 1.06426606 |
83 | MP0005375_adipose_tissue_phenotype | 1.05249519 |
84 | MP0002420_abnormal_adaptive_immunity | 1.05201188 |
85 | MP0002928_abnormal_bile_duct | 1.04635215 |
86 | MP0010630_abnormal_cardiac_muscle | 1.02685119 |
87 | MP0001819_abnormal_immune_cell | 1.02647444 |
88 | MP0003453_abnormal_keratinocyte_physiol | 1.02633352 |
89 | MP0003115_abnormal_respiratory_system | 1.01244102 |
90 | MP0004510_myositis | 1.01047390 |
91 | MP0001879_abnormal_lymphatic_vessel | 1.00990870 |
92 | MP0006054_spinal_hemorrhage | 1.00295122 |
93 | MP0000716_abnormal_immune_system | 1.00273540 |
94 | MP0002254_reproductive_system_inflammat | 0.99375595 |
95 | MP0002933_joint_inflammation | 0.99300926 |
96 | MP0003567_abnormal_fetal_cardiomyocyte | 0.98774444 |
97 | MP0009672_abnormal_birth_weight | 0.97908696 |
98 | MP0003183_abnormal_peptide_metabolism | 0.97112971 |
99 | MP0003121_genomic_imprinting | 0.96104641 |
100 | MP0003279_aneurysm | 0.95885907 |
101 | MP0002722_abnormal_immune_system | 0.95564712 |
102 | MP0004883_abnormal_blood_vessel | 0.94718976 |
103 | MP0000003_abnormal_adipose_tissue | 0.94100294 |
104 | MP0002168_other_aberrant_phenotype | 0.93213588 |
105 | MP0002723_abnormal_immune_serum | 0.93037595 |
106 | MP0001915_intracranial_hemorrhage | 0.92997556 |
107 | MP0002138_abnormal_hepatobiliary_system | 0.92712318 |
108 | MP0005623_abnormal_meninges_morphology | 0.91449713 |
109 | MP0002086_abnormal_extraembryonic_tissu | 0.91000784 |
110 | MP0003436_decreased_susceptibility_to | 0.90391345 |
111 | MP0003943_abnormal_hepatobiliary_system | 0.90325318 |
112 | MP0009053_abnormal_anal_canal | 0.89938280 |
113 | MP0002405_respiratory_system_inflammati | 0.89060684 |
114 | MP0000689_abnormal_spleen_morphology | 0.88782803 |
115 | MP0003385_abnormal_body_wall | 0.87438687 |
116 | MP0005174_abnormal_tail_pigmentation | 0.87060887 |
117 | MP0008469_abnormal_protein_level | 0.86904283 |
118 | MP0000432_abnormal_head_morphology | 0.85599718 |
119 | MP0005621_abnormal_cell_physiology | 0.85336038 |
120 | MP0002697_abnormal_eye_size | 0.84334099 |
121 | MP0001216_abnormal_epidermal_layer | 0.83804835 |
122 | MP0002088_abnormal_embryonic_growth/wei | 0.82534448 |
123 | MP0002092_abnormal_eye_morphology | 0.79917132 |
124 | MP0003984_embryonic_growth_retardation | 0.79795401 |
125 | MP0001784_abnormal_fluid_regulation | 0.79443439 |
126 | MP0002998_abnormal_bone_remodeling | 0.79309281 |
127 | MP0009840_abnormal_foam_cell | 0.79090269 |
128 | MP0008057_abnormal_DNA_replication | 0.79050037 |
129 | MP0000266_abnormal_heart_morphology | 0.78277930 |
130 | MP0009115_abnormal_fat_cell | 0.77677835 |
131 | MP0002429_abnormal_blood_cell | 0.77487932 |
132 | MP0003448_altered_tumor_morphology | 0.77260219 |
133 | MP0002132_abnormal_respiratory_system | 0.77187424 |
134 | MP0002128_abnormal_blood_circulation | 0.76925970 |
135 | MP0009931_abnormal_skin_appearance | 0.75530374 |
136 | MP0003656_abnormal_erythrocyte_physiolo | 0.74911575 |
137 | MP0005164_abnormal_response_to | 0.72196821 |
138 | MP0000249_abnormal_blood_vessel | 0.71902238 |
139 | MP0004130_abnormal_muscle_cell | 0.68584694 |
140 | MP0003795_abnormal_bone_structure | 0.67915414 |
141 | MP0005390_skeleton_phenotype | 0.67397160 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Eczematoid dermatitis (HP:0000976) | 4.60929120 |
2 | Abnormality of the fingertips (HP:0001211) | 4.50975826 |
3 | Recurrent bacterial skin infections (HP:0005406) | 3.35760581 |
4 | Recurrent abscess formation (HP:0002722) | 3.15539252 |
5 | Myositis (HP:0100614) | 3.04438337 |
6 | Macroorchidism (HP:0000053) | 2.88226607 |
7 | Broad face (HP:0000283) | 2.86835565 |
8 | Obstructive sleep apnea (HP:0002870) | 2.85533510 |
9 | Abnormality of macrophages (HP:0004311) | 2.80281401 |
10 | Orchitis (HP:0100796) | 2.79672783 |
11 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.78609976 |
12 | Short 4th metacarpal (HP:0010044) | 2.78609976 |
13 | Volvulus (HP:0002580) | 2.74118911 |
14 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.70955252 |
15 | Recurrent cutaneous fungal infections (HP:0011370) | 2.70955252 |
16 | Long eyelashes (HP:0000527) | 2.69041020 |
17 | Meningitis (HP:0001287) | 2.64469129 |
18 | Gingivitis (HP:0000230) | 2.60342909 |
19 | Hematochezia (HP:0002573) | 2.59578618 |
20 | Gastrointestinal infarctions (HP:0005244) | 2.58906850 |
21 | Retrobulbar optic neuritis (HP:0100654) | 2.58446944 |
22 | Optic neuritis (HP:0100653) | 2.58446944 |
23 | Narrow palate (HP:0000189) | 2.58424572 |
24 | Absent frontal sinuses (HP:0002688) | 2.58002941 |
25 | Pustule (HP:0200039) | 2.56247601 |
26 | Abnormality of the nasal septum (HP:0000419) | 2.53308559 |
27 | Shallow orbits (HP:0000586) | 2.51166606 |
28 | Subacute progressive viral hepatitis (HP:0006572) | 2.48747718 |
29 | Recurrent skin infections (HP:0001581) | 2.48467407 |
30 | Vasculitis (HP:0002633) | 2.44980187 |
31 | Urethral obstruction (HP:0000796) | 2.44960908 |
32 | Mediastinal lymphadenopathy (HP:0100721) | 2.44241797 |
33 | Cerebral aneurysm (HP:0004944) | 2.43415284 |
34 | Hyperacusis (HP:0010780) | 2.41860255 |
35 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.40095573 |
36 | Aortic aneurysm (HP:0004942) | 2.36336272 |
37 | Panhypogammaglobulinemia (HP:0003139) | 2.31642254 |
38 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.28841474 |
39 | Flat acetabular roof (HP:0003180) | 2.27393590 |
40 | Slow saccadic eye movements (HP:0000514) | 2.25442871 |
41 | Syringomyelia (HP:0003396) | 2.24117132 |
42 | Spinal cord lesions (HP:0100561) | 2.24117132 |
43 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.17669247 |
44 | Gastrointestinal stroma tumor (HP:0100723) | 2.16495531 |
45 | Lip pit (HP:0100267) | 2.14153873 |
46 | Chest pain (HP:0100749) | 2.12386482 |
47 | Agammaglobulinemia (HP:0004432) | 2.07650575 |
48 | Asymmetry of the thorax (HP:0001555) | 2.06573721 |
49 | Prolonged bleeding time (HP:0003010) | 2.06083050 |
50 | Rectal prolapse (HP:0002035) | 2.05240094 |
51 | Verrucae (HP:0200043) | 2.05023654 |
52 | Papilloma (HP:0012740) | 2.05023654 |
53 | Broad metatarsal (HP:0001783) | 2.03957694 |
54 | Abnormality of the 4th metacarpal (HP:0010012) | 2.02336218 |
55 | Elfin facies (HP:0004428) | 2.02242219 |
56 | Mitral valve prolapse (HP:0001634) | 2.00400992 |
57 | Enlarged penis (HP:0000040) | 1.98090687 |
58 | Interstitial pulmonary disease (HP:0006530) | 1.97169292 |
59 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.96139154 |
60 | Viral hepatitis (HP:0006562) | 1.96051258 |
61 | Obstructive lung disease (HP:0006536) | 1.95996123 |
62 | Chronic obstructive pulmonary disease (HP:0006510) | 1.95996123 |
63 | Trigonocephaly (HP:0000243) | 1.95871486 |
64 | Recurrent viral infections (HP:0004429) | 1.95519854 |
65 | Keratoconjunctivitis sicca (HP:0001097) | 1.95179519 |
66 | Arterial thrombosis (HP:0004420) | 1.95044470 |
67 | Encephalitis (HP:0002383) | 1.94470160 |
68 | Renovascular hypertension (HP:0100817) | 1.92802055 |
69 | Spondylolisthesis (HP:0003302) | 1.89746338 |
70 | Emphysema (HP:0002097) | 1.89519655 |
71 | Deep philtrum (HP:0002002) | 1.89466015 |
72 | Limited elbow extension (HP:0001377) | 1.89192258 |
73 | Neoplasm of the adrenal cortex (HP:0100641) | 1.88808340 |
74 | Osteomyelitis (HP:0002754) | 1.88513928 |
75 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.88493521 |
76 | Abnormality of T cells (HP:0002843) | 1.88301894 |
77 | Cellulitis (HP:0100658) | 1.87817825 |
78 | Pulmonary infiltrates (HP:0002113) | 1.87789655 |
79 | Truncal obesity (HP:0001956) | 1.87752871 |
80 | Obsessive-compulsive behavior (HP:0000722) | 1.87196098 |
81 | Aneurysm (HP:0002617) | 1.87138580 |
82 | Hemoptysis (HP:0002105) | 1.86965953 |
83 | Sparse lateral eyebrow (HP:0005338) | 1.86719042 |
84 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.86677606 |
85 | Recurrent bronchitis (HP:0002837) | 1.85729816 |
86 | Gastrointestinal carcinoma (HP:0002672) | 1.84487190 |
87 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.84487190 |
88 | Thick eyebrow (HP:0000574) | 1.84342257 |
89 | Protrusio acetabuli (HP:0003179) | 1.83678580 |
90 | Thin bony cortex (HP:0002753) | 1.83361974 |
91 | Colitis (HP:0002583) | 1.82944254 |
92 | Papilledema (HP:0001085) | 1.82759631 |
93 | Bowel diverticulosis (HP:0005222) | 1.82640546 |
94 | Stomatitis (HP:0010280) | 1.81623694 |
95 | Inflammation of the large intestine (HP:0002037) | 1.81564127 |
96 | Epistaxis (HP:0000421) | 1.81545557 |
97 | Gastrointestinal inflammation (HP:0004386) | 1.81415362 |
98 | Broad thumb (HP:0011304) | 1.80023679 |
99 | Persistence of primary teeth (HP:0006335) | 1.79613977 |
100 | Dislocated radial head (HP:0003083) | 1.79589171 |
101 | Supernumerary ribs (HP:0005815) | 1.79447438 |
102 | Lymphopenia (HP:0001888) | 1.79143112 |
103 | Increased density of long bones (HP:0006392) | 1.79067582 |
104 | Neonatal hypoglycemia (HP:0001998) | 1.78633080 |
105 | Dysmetric saccades (HP:0000641) | 1.78257304 |
106 | Urticaria (HP:0001025) | 1.78055977 |
107 | Milia (HP:0001056) | 1.77919000 |
108 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.77901837 |
109 | Distal lower limb amyotrophy (HP:0008944) | 1.77687536 |
110 | Heterotopia (HP:0002282) | 1.77683188 |
111 | Acute myeloid leukemia (HP:0004808) | 1.77511880 |
112 | Ankle contracture (HP:0006466) | 1.77368755 |
113 | Recurrent fungal infections (HP:0002841) | 1.77339240 |
114 | T lymphocytopenia (HP:0005403) | 1.76567052 |
115 | Vertebral arch anomaly (HP:0008438) | 1.76480079 |
116 | Autoimmune hemolytic anemia (HP:0001890) | 1.76273083 |
117 | Smooth philtrum (HP:0000319) | 1.76017915 |
118 | Restrictive lung disease (HP:0002091) | 1.75216387 |
119 | Leiomyosarcoma (HP:0100243) | 1.74714914 |
120 | Uterine leiomyosarcoma (HP:0002891) | 1.74714914 |
121 | Fatigue (HP:0012378) | 1.74298075 |
122 | Metaphyseal cupping (HP:0003021) | 1.74017920 |
123 | Granulocytopenia (HP:0001913) | 1.73628025 |
124 | Increased nuchal translucency (HP:0010880) | 1.73401096 |
125 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.73250043 |
126 | Abnormality of the columella (HP:0009929) | 1.73124590 |
127 | Germ cell neoplasia (HP:0100728) | 1.72590593 |
128 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.72221511 |
129 | Bladder carcinoma (HP:0002862) | 1.72092925 |
130 | Bladder neoplasm (HP:0009725) | 1.72092925 |
131 | Hereditary nonpolyposis colorectal carcinoma (HP:0006716) | 1.71457445 |
132 | Aortic dissection (HP:0002647) | 1.69443484 |
133 | Ulnar bowing (HP:0003031) | 1.69411805 |
134 | Keratoconjunctivitis (HP:0001096) | 1.69335609 |
135 | Polygenic inheritance (HP:0010982) | 1.69202592 |
136 | Skin ulcer (HP:0200042) | 1.68874890 |
137 | Abnormality of the radial head (HP:0003995) | 1.68296177 |
138 | Gingival bleeding (HP:0000225) | 1.67942500 |
139 | Increased connective tissue (HP:0009025) | 1.67588105 |
140 | Spontaneous hematomas (HP:0007420) | 1.67436589 |
141 | Abnormality of T cell number (HP:0011839) | 1.67407480 |
142 | Abnormality of the peritoneum (HP:0002585) | 1.67217650 |
143 | Periodontitis (HP:0000704) | 1.66882359 |
144 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.66469539 |
145 | Osteolytic defects of the hand bones (HP:0009699) | 1.66469539 |
146 | Dilatation of the ascending aorta (HP:0005111) | 1.66114356 |
147 | Hypoplastic ischia (HP:0003175) | 1.65852884 |
148 | Abnormality of the thoracic spine (HP:0100711) | 1.65609422 |
149 | Atrophic scars (HP:0001075) | 1.64369748 |
150 | Ureteral obstruction (HP:0006000) | 1.63952156 |
151 | Cutis marmorata (HP:0000965) | 1.61702166 |
152 | Broad palm (HP:0001169) | 1.61432372 |
153 | Bladder diverticulum (HP:0000015) | 1.61038565 |
154 | Low anterior hairline (HP:0000294) | 1.60760850 |
155 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.60016358 |
156 | Disproportionate tall stature (HP:0001519) | 1.57685874 |
157 | Pseudobulbar signs (HP:0002200) | 1.57359193 |
158 | Thyroiditis (HP:0100646) | 1.57273124 |
159 | Exostoses (HP:0100777) | 1.56952694 |
160 | Renal duplication (HP:0000075) | 1.56898148 |
161 | Abnormality of the parietal bone (HP:0002696) | 1.55890064 |
162 | Myocardial infarction (HP:0001658) | 1.54432224 |
163 | Abnormality of the frontal sinuses (HP:0002687) | 1.54286554 |
164 | Ureteral stenosis (HP:0000071) | 1.52905072 |
165 | Abnormality of the intervertebral disk (HP:0005108) | 1.51540241 |
166 | Increased IgE level (HP:0003212) | 1.51414707 |
167 | Autoimmune thrombocytopenia (HP:0001973) | 1.51202542 |
168 | Hypoplasia of the maxilla (HP:0000327) | 1.50739549 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDK12 | 4.35433252 |
2 | PRPF4B | 3.72928322 |
3 | BRD4 | 2.65705964 |
4 | RIPK4 | 2.59031798 |
5 | FGFR3 | 2.33670381 |
6 | SMG1 | 2.31630138 |
7 | CAMK1D | 2.28805707 |
8 | CAMK1G | 2.20026615 |
9 | MAP3K10 | 2.17788538 |
10 | LATS1 | 2.15985841 |
11 | SIK1 | 2.13612466 |
12 | EEF2K | 2.10086889 |
13 | TRIB3 | 1.98556235 |
14 | MAP3K13 | 1.93420113 |
15 | MAP4K1 | 1.88329864 |
16 | STK10 | 1.77694272 |
17 | PTK6 | 1.73048413 |
18 | PKN2 | 1.71107327 |
19 | EPHA3 | 1.66404702 |
20 | BLK | 1.64894474 |
21 | FRK | 1.64059870 |
22 | IRAK4 | 1.57669026 |
23 | JAK1 | 1.57083547 |
24 | RIPK1 | 1.54422491 |
25 | TTN | 1.53593298 |
26 | FGFR4 | 1.52655229 |
27 | DMPK | 1.51693713 |
28 | SIK3 | 1.43691135 |
29 | FGFR2 | 1.42322685 |
30 | SIK2 | 1.34951810 |
31 | CDK6 | 1.34326984 |
32 | SGK3 | 1.33266344 |
33 | ERN1 | 1.32202257 |
34 | EPHB1 | 1.31531298 |
35 | TAOK1 | 1.31148310 |
36 | STK3 | 1.31013383 |
37 | TGFBR2 | 1.28973000 |
38 | INSRR | 1.28823742 |
39 | MTOR | 1.26512808 |
40 | TAOK3 | 1.23169573 |
41 | TYK2 | 1.22617674 |
42 | PDGFRA | 1.21957830 |
43 | CHUK | 1.21851486 |
44 | MAP3K3 | 1.20253550 |
45 | JAK3 | 1.12321270 |
46 | TBK1 | 1.10095280 |
47 | MAP3K7 | 1.05763539 |
48 | MAP3K1 | 1.05523137 |
49 | FES | 1.05496000 |
50 | NUAK1 | 1.05320752 |
51 | PDGFRB | 1.05270834 |
52 | ALK | 1.04921893 |
53 | CDK9 | 1.04550098 |
54 | WNK1 | 1.00007369 |
55 | CLK1 | 0.97967380 |
56 | HCK | 0.93646555 |
57 | SGK2 | 0.92469614 |
58 | KSR2 | 0.92234715 |
59 | ITK | 0.91915103 |
60 | MAP2K3 | 0.90881252 |
61 | CSF1R | 0.89901346 |
62 | HIPK2 | 0.89774362 |
63 | BMX | 0.89527254 |
64 | MAP3K14 | 0.89261858 |
65 | PRKCH | 0.88024347 |
66 | TRPM7 | 0.87011769 |
67 | BTK | 0.83881065 |
68 | PRKD2 | 0.83453976 |
69 | DYRK1B | 0.82547646 |
70 | LRRK2 | 0.81554119 |
71 | PIM1 | 0.80490982 |
72 | SYK | 0.80397466 |
73 | IRAK3 | 0.79511940 |
74 | PDPK1 | 0.79509732 |
75 | CSK | 0.78934541 |
76 | PDK1 | 0.78872155 |
77 | IRAK1 | 0.78133472 |
78 | MARK3 | 0.77720600 |
79 | MAP3K2 | 0.74353104 |
80 | MARK2 | 0.73800519 |
81 | IKBKE | 0.73248681 |
82 | TAOK2 | 0.73164982 |
83 | YES1 | 0.72101056 |
84 | STK4 | 0.71327999 |
85 | CAMKK1 | 0.71086161 |
86 | MAPK12 | 0.70499086 |
87 | CDC42BPA | 0.70260814 |
88 | RPS6KA4 | 0.69685689 |
89 | CDK4 | 0.69684370 |
90 | NEK9 | 0.69364377 |
91 | PAK2 | 0.69319628 |
92 | IRAK2 | 0.68439615 |
93 | MAPK11 | 0.68036072 |
94 | FGR | 0.67841338 |
95 | TXK | 0.63638187 |
96 | KIT | 0.62007925 |
97 | STK38 | 0.61122535 |
98 | ICK | 0.60900847 |
99 | MAPK7 | 0.60814521 |
100 | ZAP70 | 0.60362038 |
101 | EPHA2 | 0.60073061 |
102 | FGFR1 | 0.59902907 |
103 | MELK | 0.59216369 |
104 | MAP2K2 | 0.58268432 |
105 | PASK | 0.57730926 |
106 | ATR | 0.57440323 |
107 | MAP3K6 | 0.56978703 |
108 | NLK | 0.56962063 |
109 | PTK2 | 0.56614564 |
110 | LCK | 0.56028460 |
111 | FLT3 | 0.55462547 |
112 | RPS6KB2 | 0.54627448 |
113 | JAK2 | 0.54436901 |
114 | ATM | 0.54321665 |
115 | NEK2 | 0.54299537 |
116 | LYN | 0.53507631 |
117 | RET | 0.53262134 |
118 | RPS6KC1 | 0.53106123 |
119 | RPS6KL1 | 0.53106123 |
120 | IKBKB | 0.52689345 |
121 | PRKAA2 | 0.52319306 |
122 | RPS6KA2 | 0.52084734 |
123 | TNK2 | 0.50526572 |
124 | CHEK1 | 0.48993026 |
125 | CAMK4 | 0.47708659 |
126 | MAPK1 | 0.45620504 |
127 | MAPK14 | 0.45377683 |
128 | GRK6 | 0.45274883 |
129 | PRKD1 | 0.45072736 |
130 | DDR2 | 0.43437741 |
131 | MAPK8 | 0.42849743 |
132 | ZAK | 0.41664254 |
133 | AKT1 | 0.41415846 |
134 | CSNK1D | 0.40429444 |
135 | RPS6KA6 | 0.39500330 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Lysine degradation_Homo sapiens_hsa00310 | 2.29336530 |
2 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.01151131 |
3 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.83321336 |
4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.79893634 |
5 | Adherens junction_Homo sapiens_hsa04520 | 1.57591269 |
6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.56963580 |
7 | Other glycan degradation_Homo sapiens_hsa00511 | 1.51539837 |
8 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.50400708 |
9 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.47695779 |
10 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.44374356 |
11 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.44127813 |
12 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.36834433 |
13 | Allograft rejection_Homo sapiens_hsa05330 | 1.36531847 |
14 | Endometrial cancer_Homo sapiens_hsa05213 | 1.35377107 |
15 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.34648764 |
16 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.33357146 |
17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.32545021 |
18 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.29859490 |
19 | Focal adhesion_Homo sapiens_hsa04510 | 1.29762919 |
20 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.29751850 |
21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.27750480 |
22 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.26763632 |
23 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.26245337 |
24 | Prostate cancer_Homo sapiens_hsa05215 | 1.26244081 |
25 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.24066345 |
26 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.22911925 |
27 | Leishmaniasis_Homo sapiens_hsa05140 | 1.22542121 |
28 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.21626301 |
29 | Measles_Homo sapiens_hsa05162 | 1.20082607 |
30 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.19674914 |
31 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.16393349 |
32 | Insulin resistance_Homo sapiens_hsa04931 | 1.15724860 |
33 | Viral myocarditis_Homo sapiens_hsa05416 | 1.15708656 |
34 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.13843572 |
35 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.13651747 |
36 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.12773019 |
37 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.12757491 |
38 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.10367824 |
39 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.10249641 |
40 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.09974907 |
41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.08520898 |
42 | Platelet activation_Homo sapiens_hsa04611 | 1.06422708 |
43 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.05342523 |
44 | HTLV-I infection_Homo sapiens_hsa05166 | 1.05212329 |
45 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.05055744 |
46 | Hepatitis B_Homo sapiens_hsa05161 | 1.04262732 |
47 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.03813450 |
48 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.02361455 |
49 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.01982734 |
50 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.01175094 |
51 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.00990860 |
52 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.00826923 |
53 | Glioma_Homo sapiens_hsa05214 | 1.00637697 |
54 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.99887424 |
55 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.99605412 |
56 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.99589737 |
57 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.98296849 |
58 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.96953858 |
59 | Colorectal cancer_Homo sapiens_hsa05210 | 0.95656147 |
60 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.95050205 |
61 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.94529028 |
62 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.94010627 |
63 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.93873382 |
64 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.93018262 |
65 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.92827239 |
66 | Malaria_Homo sapiens_hsa05144 | 0.92621587 |
67 | Pathways in cancer_Homo sapiens_hsa05200 | 0.86910347 |
68 | Influenza A_Homo sapiens_hsa05164 | 0.85346874 |
69 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.84424488 |
70 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.83866917 |
71 | Amoebiasis_Homo sapiens_hsa05146 | 0.83467015 |
72 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.83431392 |
73 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.82806562 |
74 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.82340069 |
75 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.82274171 |
76 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.80208548 |
77 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.79018851 |
78 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.78687803 |
79 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.77807583 |
80 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.76265882 |
81 | Apoptosis_Homo sapiens_hsa04210 | 0.75960162 |
82 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.75034139 |
83 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.74733738 |
84 | Hepatitis C_Homo sapiens_hsa05160 | 0.74453704 |
85 | Legionellosis_Homo sapiens_hsa05134 | 0.73523924 |
86 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.72642172 |
87 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.71351397 |
88 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.71186140 |
89 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.69301148 |
90 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.69168187 |
91 | Endocytosis_Homo sapiens_hsa04144 | 0.67080739 |
92 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.65633377 |
93 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.64783700 |
94 | Long-term potentiation_Homo sapiens_hsa04720 | 0.63827320 |
95 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.63600416 |
96 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.63048333 |
97 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.63005238 |
98 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.62557217 |
99 | Melanoma_Homo sapiens_hsa05218 | 0.62045782 |
100 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.61745242 |
101 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.61630097 |
102 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.61391461 |
103 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.61214505 |
104 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.60903478 |
105 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.59349084 |
106 | Pertussis_Homo sapiens_hsa05133 | 0.58828153 |
107 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.58122523 |
108 | Thyroid cancer_Homo sapiens_hsa05216 | 0.57825877 |
109 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.57671093 |
110 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.56096964 |
111 | ABC transporters_Homo sapiens_hsa02010 | 0.55996742 |
112 | Bladder cancer_Homo sapiens_hsa05219 | 0.55944148 |
113 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.55161518 |
114 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.54896114 |
115 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.54401121 |
116 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.54328807 |
117 | Shigellosis_Homo sapiens_hsa05131 | 0.52142935 |
118 | Tuberculosis_Homo sapiens_hsa05152 | 0.51806207 |