KDM3B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)4.48441069
2nuclear pore complex assembly (GO:0051292)4.42705490
3pre-miRNA processing (GO:0031054)4.35441660
4negative regulation of histone methylation (GO:0031061)4.16641284
5nuclear pore organization (GO:0006999)4.13923015
6regulation of RNA export from nucleus (GO:0046831)3.99448351
7negative regulation of erythrocyte differentiation (GO:0045647)3.84499404
8regulation of NFAT protein import into nucleus (GO:0051532)3.78775976
9histone H3-K4 methylation (GO:0051568)3.76642238
10histone H3-K4 trimethylation (GO:0080182)3.72167310
11regulation of histone H3-K27 methylation (GO:0061085)3.61670207
12regulation of histone H3-K9 methylation (GO:0051570)3.54785930
13embryonic process involved in female pregnancy (GO:0060136)3.53305346
14cytoplasmic mRNA processing body assembly (GO:0033962)3.52696261
15heterochromatin organization (GO:0070828)3.41761647
16pore complex assembly (GO:0046931)3.35844482
17glucocorticoid receptor signaling pathway (GO:0042921)3.30962454
18NLS-bearing protein import into nucleus (GO:0006607)3.23984766
19embryonic camera-type eye morphogenesis (GO:0048596)3.23116076
20DNA unwinding involved in DNA replication (GO:0006268)3.22708876
21dosage compensation (GO:0007549)3.20992662
22protein localization to kinetochore (GO:0034501)3.17826692
23regulation of nucleobase-containing compound transport (GO:0032239)3.17659583
24positive regulation of histone deacetylation (GO:0031065)3.15119099
25peptidyl-lysine trimethylation (GO:0018023)3.14876088
26mRNA stabilization (GO:0048255)3.12959627
27RNA stabilization (GO:0043489)3.12959627
28positive regulation of gene expression, epigenetic (GO:0045815)3.12567383
29DNA duplex unwinding (GO:0032508)3.12208414
30negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.11757225
31peptidyl-threonine phosphorylation (GO:0018107)3.10480863
32DNA geometric change (GO:0032392)3.10417086
33regulation of sister chromatid cohesion (GO:0007063)3.10262171
34histone H3-K9 methylation (GO:0051567)3.08651561
35definitive hemopoiesis (GO:0060216)3.06293995
36peptidyl-threonine modification (GO:0018210)3.04827018
37histone H4-K16 acetylation (GO:0043984)3.03447177
38histone lysine methylation (GO:0034968)3.02959131
39positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.01776257
40positive regulation of mitotic sister chromatid separation (GO:1901970)3.01703069
41positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.01703069
42positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.01703069
43regulation of translational fidelity (GO:0006450)3.01489169
44histone H3-K36 demethylation (GO:0070544)3.01114967
45positive regulation of gamma-delta T cell activation (GO:0046645)3.01062628
46protein demethylation (GO:0006482)2.99328994
47protein dealkylation (GO:0008214)2.99328994
48regulation of DNA endoreduplication (GO:0032875)2.96262748
49peptidyl-lysine dimethylation (GO:0018027)2.95815996
50planar cell polarity pathway involved in neural tube closure (GO:0090179)2.93424220
51cytoskeletal anchoring at plasma membrane (GO:0007016)2.92064869
52mitotic nuclear envelope disassembly (GO:0007077)2.90790780
53histone H3-K9 modification (GO:0061647)2.89386318
54regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.88703972
55positive regulation of SMAD protein import into nucleus (GO:0060391)2.88556513
56histone H3-K9 demethylation (GO:0033169)2.88093638
57regulation of gamma-delta T cell differentiation (GO:0045586)2.86615996
58regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.84479500
59regulation of chromatin binding (GO:0035561)2.83946022
60chromatin assembly (GO:0031497)2.83923185
61sister chromatid segregation (GO:0000819)2.83515323
62corticosteroid receptor signaling pathway (GO:0031958)2.83460435
63nucleosome disassembly (GO:0006337)2.83240818
64protein-DNA complex disassembly (GO:0032986)2.83240818
65regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.82924204
66determination of adult lifespan (GO:0008340)2.82424889
67epithelial cell differentiation involved in prostate gland development (GO:0060742)2.78989092
68paraxial mesoderm development (GO:0048339)2.78949573
69negative regulation of cell killing (GO:0031342)2.77590996
70negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.77590996
71positive regulation of chromosome segregation (GO:0051984)2.77358781
72embryonic eye morphogenesis (GO:0048048)2.77295099
73negative regulation of RNA splicing (GO:0033119)2.76928461
74negative regulation of histone modification (GO:0031057)2.75313642
75response to epidermal growth factor (GO:0070849)2.75074560
76negative regulation of chromatin modification (GO:1903309)2.73996283
77protein export from nucleus (GO:0006611)2.73567982
78intracellular estrogen receptor signaling pathway (GO:0030520)2.73309306
79membrane disassembly (GO:0030397)2.72815711
80nuclear envelope disassembly (GO:0051081)2.72815711
81histone H4-K12 acetylation (GO:0043983)2.71722337
82negative regulation of translation, ncRNA-mediated (GO:0040033)2.70840836
83regulation of translation, ncRNA-mediated (GO:0045974)2.70840836
84negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.70840836
85negative regulation of mRNA processing (GO:0050686)2.69505527
86adherens junction assembly (GO:0034333)2.69504402
87histone H4-K5 acetylation (GO:0043981)2.69120799
88histone H4-K8 acetylation (GO:0043982)2.69120799
89cellular response to epidermal growth factor stimulus (GO:0071364)2.68354402
90mitotic chromosome condensation (GO:0007076)2.67239213
91positive thymic T cell selection (GO:0045059)2.67158958
92histone methylation (GO:0016571)2.66639269
93chromatin silencing (GO:0006342)2.66553911
94negative regulation of granulocyte differentiation (GO:0030853)2.66020298
95protein localization to chromosome, centromeric region (GO:0071459)2.65643905
96regulation of spindle organization (GO:0090224)2.64589748
97negative regulation of gene expression, epigenetic (GO:0045814)2.63358369
98negative regulation of myotube differentiation (GO:0010832)2.61532717
99regulation of mitotic spindle organization (GO:0060236)2.60503818
100cell-substrate adherens junction assembly (GO:0007045)2.60427177
101focal adhesion assembly (GO:0048041)2.60427177
102phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.60031473
103alternative mRNA splicing, via spliceosome (GO:0000380)2.59943136
104regulation of histone methylation (GO:0031060)2.59431267
105histone lysine demethylation (GO:0070076)2.59355504
106histone H2A monoubiquitination (GO:0035518)2.58545867
107negative regulation of mRNA metabolic process (GO:1903312)2.58034449
108regulation of gamma-delta T cell activation (GO:0046643)2.57638661
109peptidyl-lysine methylation (GO:0018022)2.56790424
110regulation of mRNA stability (GO:0043488)2.56292848
111stress granule assembly (GO:0034063)2.55866565
112gene silencing (GO:0016458)2.53941102
113trophectodermal cell differentiation (GO:0001829)2.53684376
114regulation of histone H3-K4 methylation (GO:0051569)2.52114847
115positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.51705814
116histone mRNA catabolic process (GO:0071044)2.50730419
117negative regulation of DNA repair (GO:0045738)2.47950990
118spliceosomal tri-snRNP complex assembly (GO:0000244)2.47741605
119DNA topological change (GO:0006265)2.47587338
120positive regulation by host of viral transcription (GO:0043923)2.46457406
121nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.46366822
122histone demethylation (GO:0016577)2.45891055
123histone H4 acetylation (GO:0043967)2.44902428
124embryonic placenta development (GO:0001892)2.42247098
125cellular hyperosmotic response (GO:0071474)2.41533900
126embryonic retina morphogenesis in camera-type eye (GO:0060059)2.41419870
127mitotic sister chromatid segregation (GO:0000070)2.40657520
1283-UTR-mediated mRNA stabilization (GO:0070935)2.40551198
129DNA conformation change (GO:0071103)2.40461111
130regulation of chromatin silencing (GO:0031935)2.39248540
131regulation of RNA stability (GO:0043487)2.39081453
132eye morphogenesis (GO:0048592)2.35914187
133insulin-like growth factor receptor signaling pathway (GO:0048009)2.35813166
134protein localization to microtubule (GO:0035372)2.32862056
135response to laminar fluid shear stress (GO:0034616)2.29621027
136regulation of ARF protein signal transduction (GO:0032012)2.27619529
137interkinetic nuclear migration (GO:0022027)2.27503763
138coronary vasculature morphogenesis (GO:0060977)2.23552729
139regulation of glucose import in response to insulin stimulus (GO:2001273)2.22792118
140establishment of nucleus localization (GO:0040023)2.19529191
141histone H4 deacetylation (GO:0070933)2.18171671
142response to muramyl dipeptide (GO:0032495)2.17349495
143morphogenesis of an epithelial sheet (GO:0002011)2.16115356
144cellular protein complex localization (GO:0034629)2.14313961
145regulation of stem cell maintenance (GO:2000036)2.14210292
146regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.12872140
147establishment of spindle orientation (GO:0051294)2.11010405
148convergent extension (GO:0060026)2.10912274
149positive regulation of protein import into nucleus, translocation (GO:0033160)2.09708476

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.62600145
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.91071884
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.75767150
4MYC_22102868_ChIP-Seq_BL_Human3.87532052
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.52677836
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.97107597
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.80595917
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.68640944
9VDR_21846776_ChIP-Seq_THP-1_Human2.59726854
10TCF7_22412390_ChIP-Seq_EML_Mouse2.52897350
11KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.18348913
12KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.13332520
13RBPJ_22232070_ChIP-Seq_NCS_Mouse2.12507113
14KDM2B_26808549_Chip-Seq_DND41_Human2.09714243
15SALL1_21062744_ChIP-ChIP_HESCs_Human2.03064549
16KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.97620749
17TP63_19390658_ChIP-ChIP_HaCaT_Human1.97560483
18SCL_19346495_ChIP-Seq_HPC-7_Human1.97307463
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.94543032
20CIITA_25753668_ChIP-Seq_RAJI_Human1.89477732
21CLOCK_20551151_ChIP-Seq_293T_Human1.88504099
22SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.85029733
23KDM2B_26808549_Chip-Seq_SUP-B15_Human1.82574520
24UTX_26944678_Chip-Seq_JUKART_Human1.82417028
25MAF_26560356_Chip-Seq_TH1_Human1.81855233
26FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.76287286
27SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.75323594
28TP63_17297297_ChIP-ChIP_HaCaT_Human1.73550069
29E2F1_21310950_ChIP-Seq_MCF-7_Human1.73190654
30ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.73171555
31GATA1_22025678_ChIP-Seq_K562_Human1.69356891
32MYB_26560356_Chip-Seq_TH1_Human1.69356070
33IRF8_22096565_ChIP-ChIP_GC-B_Human1.65780884
34MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.64755469
35MYB_26560356_Chip-Seq_TH2_Human1.61959436
36STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.60061090
37ZFP281_27345836_Chip-Seq_ESCs_Mouse1.55821148
38SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.54242183
39RUNX_20019798_ChIP-Seq_JUKART_Human1.53535083
40STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.52425328
41* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.50024785
42KDM2B_26808549_Chip-Seq_JURKAT_Human1.48712929
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.47399497
44VDR_24763502_ChIP-Seq_THP-1_Human1.46766731
45TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.44431087
46PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.44066327
47ELK3_25401928_ChIP-Seq_HUVEC_Human1.42151385
48MYB_21317192_ChIP-Seq_ERMYB_Mouse1.42041863
49PKCTHETA_26484144_Chip-Seq_BREAST_Human1.41181492
50BRD4_27068464_Chip-Seq_AML-cells_Mouse1.40123414
51* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.39265201
52ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.37853308
53KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.35923290
54KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.35923290
55KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.35923290
56E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.35476957
57WT1_19549856_ChIP-ChIP_CCG9911_Human1.34389427
58* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.33709256
59ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.32873916
60NCOR1_26117541_ChIP-Seq_K562_Human1.32790395
61SOX9_24532713_ChIP-Seq_HFSC_Mouse1.31073499
62RACK7_27058665_Chip-Seq_MCF-7_Human1.29062577
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.29049291
64SPI1_23127762_ChIP-Seq_K562_Human1.28936518
65SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.28614147
66MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.27509155
67* FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.25359450
68SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.25109597
69STAT6_21828071_ChIP-Seq_BEAS2B_Human1.25017519
70RUNX1_22412390_ChIP-Seq_EML_Mouse1.24963327
71GATA1_19941826_ChIP-Seq_K562_Human1.22857055
72SOX2_27498859_Chip-Seq_STOMACH_Mouse1.22188146
73CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.22008214
74TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.19368289
75TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.19183706
76CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.17938478
77CTNNB1_20460455_ChIP-Seq_HCT116_Human1.16844483
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.16727147
79VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.16641741
80IRF8_27001747_Chip-Seq_BMDM_Mouse1.16573441
81KDM5A_27292631_Chip-Seq_BREAST_Human1.15832725
82TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.14222436
83NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.14035021
84TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13489607
85P300_27058665_Chip-Seq_ZR-75-30cells_Human1.12268326
86NANOG_21062744_ChIP-ChIP_HESCs_Human1.11755556
87KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.11701218
88CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.09163475
89* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09002280
90ISL1_27105846_Chip-Seq_CPCs_Mouse1.08462215
91AR_21909140_ChIP-Seq_LNCAP_Human1.07968548
92KLF4_18555785_ChIP-Seq_MESCs_Mouse1.07156915
93NFIB_24661679_ChIP-Seq_LUNG_Mouse1.07103256
94ZFP281_18757296_ChIP-ChIP_E14_Mouse1.06571208
95GATA1_19941827_ChIP-Seq_MEL_Mouse1.06268325
96EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.06174890
97MYC_19079543_ChIP-ChIP_MESCs_Mouse1.05114723
98MAF_26560356_Chip-Seq_TH2_Human1.04278621
99CHD1_26751641_Chip-Seq_LNCaP_Human1.03813611
100TCF3_18692474_ChIP-Seq_MEFs_Mouse1.03302476
101* SPI1_23547873_ChIP-Seq_NB4_Human1.01048340
102EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.00480278
103SALL4_18804426_ChIP-ChIP_XEN_Mouse0.99742852
104IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.99443436
105ESR2_21235772_ChIP-Seq_MCF-7_Human0.98645369
106GATA2_19941826_ChIP-Seq_K562_Human0.98616880
107TCF3_18692474_ChIP-Seq_MESCs_Mouse0.97344566
108TBX20_22080862_ChIP-Seq_HEART_Mouse0.96134191
109TBX20_22328084_ChIP-Seq_HEART_Mouse0.96134191
110HIF1A_21447827_ChIP-Seq_MCF-7_Human0.94774722
111ESR1_20079471_ChIP-ChIP_T-47D_Human0.93897970
112TFEB_21752829_ChIP-Seq_HELA_Human0.93367191
113KDM2B_26808549_Chip-Seq_K562_Human0.92896527
114NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92746031
115HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.91742644
116WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.91620689
117ESR1_15608294_ChIP-ChIP_MCF-7_Human0.90882831
118FOXO3_23340844_ChIP-Seq_DLD1_Human0.90540854
119RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.89762001
120* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.89593378
121STAT3_1855785_ChIP-Seq_MESCs_Mouse0.89474490
122NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.89275520
123ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.89242926
124SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.89200227
125DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.87575272
126RUNX1_27514584_Chip-Seq_MCF-7_Human0.87405105
127DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87091626
128POU5F1_16518401_ChIP-PET_MESCs_Mouse0.86606602

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005076_abnormal_cell_differentiation3.01891564
2MP0002396_abnormal_hematopoietic_system2.90150480
3MP0010352_gastrointestinal_tract_polyps2.88781781
4MP0000569_abnormal_digit_pigmentation2.83272637
5MP0005409_darkened_coat_color2.77871622
6MP0008057_abnormal_DNA_replication2.55111114
7MP0009278_abnormal_bone_marrow2.45833643
8MP0004808_abnormal_hematopoietic_stem2.41605139
9MP0010094_abnormal_chromosome_stability2.35283801
10MP0003111_abnormal_nucleus_morphology2.31662705
11MP0010307_abnormal_tumor_latency2.22349973
12MP0005451_abnormal_body_composition2.21525744
13MP0003705_abnormal_hypodermis_morpholog2.16048338
14MP0003077_abnormal_cell_cycle2.11511117
15MP0003300_gastrointestinal_ulcer2.10905139
16MP0003303_peritoneal_inflammation1.90285060
17MP0002166_altered_tumor_susceptibility1.78654457
18MP0000350_abnormal_cell_proliferation1.74234071
19MP0000733_abnormal_muscle_development1.64392421
20MP0003693_abnormal_embryo_hatching1.62743386
21MP0004197_abnormal_fetal_growth/weight/1.60448817
22MP0001730_embryonic_growth_arrest1.58952895
23MP0004957_abnormal_blastocyst_morpholog1.57959833
24MP0002086_abnormal_extraembryonic_tissu1.57314726
25MP0001800_abnormal_humoral_immune1.57257519
26MP0003566_abnormal_cell_adhesion1.56492686
27MP0000703_abnormal_thymus_morphology1.56444446
28MP0002398_abnormal_bone_marrow1.56065022
29MP0005397_hematopoietic_system_phenotyp1.53693805
30MP0001545_abnormal_hematopoietic_system1.53693805
31MP0001672_abnormal_embryogenesis/_devel1.52714491
32MP0005380_embryogenesis_phenotype1.52714491
33MP0003984_embryonic_growth_retardation1.52444596
34MP0002088_abnormal_embryonic_growth/wei1.52302318
35MP0003787_abnormal_imprinting1.50683769
36MP0002084_abnormal_developmental_patter1.49551480
37MP0003763_abnormal_thymus_physiology1.48725690
38MP0004233_abnormal_muscle_weight1.48601706
39MP0008058_abnormal_DNA_repair1.47398546
40MP0005666_abnormal_adipose_tissue1.47141178
41MP0000685_abnormal_immune_system1.44568591
42MP0003828_pulmonary_edema1.36890890
43MP0008007_abnormal_cellular_replicative1.34228842
44MP0002085_abnormal_embryonic_tissue1.33642576
45MP0008877_abnormal_DNA_methylation1.32661182
46MP0001835_abnormal_antigen_presentation1.31527552
47MP0001697_abnormal_embryo_size1.31001917
48MP0002722_abnormal_immune_system1.29817802
49MP0000689_abnormal_spleen_morphology1.27359144
50MP0009053_abnormal_anal_canal1.24607643
51MP0002877_abnormal_melanocyte_morpholog1.24112944
52MP0001915_intracranial_hemorrhage1.23612075
53MP0000490_abnormal_crypts_of1.23582878
54MP0009703_decreased_birth_body1.22328715
55MP0002452_abnormal_antigen_presenting1.22258266
56MP0005387_immune_system_phenotype1.22225066
57MP0001790_abnormal_immune_system1.22225066
58MP0002006_tumorigenesis1.22135996
59MP0001849_ear_inflammation1.21218886
60MP0002925_abnormal_cardiovascular_devel1.18488985
61MP0000716_abnormal_immune_system1.18086248
62MP0000465_gastrointestinal_hemorrhage1.17692927
63MP0005023_abnormal_wound_healing1.17176292
64MP0008260_abnormal_autophagy1.14925240
65MP0008961_abnormal_basal_metabolism1.13813768
66MP0001293_anophthalmia1.13628668
67MP0002080_prenatal_lethality1.12112029
68MP0003121_genomic_imprinting1.10740354
69MP0002420_abnormal_adaptive_immunity1.09809191
70MP0003567_abnormal_fetal_cardiomyocyte1.08762654
71MP0005248_abnormal_Harderian_gland1.08317676
72MP0003890_abnormal_embryonic-extraembry1.07662077
73MP0000428_abnormal_craniofacial_morphol1.07658179
74MP0001819_abnormal_immune_cell1.07654665
75MP0004858_abnormal_nervous_system1.06410626
76MP0002429_abnormal_blood_cell1.04564061
77MP0010234_abnormal_vibrissa_follicle1.03537947
78MP0002019_abnormal_tumor_incidence1.03403001
79MP0003045_fibrosis1.01952404
80MP0010630_abnormal_cardiac_muscle1.00764106
81MP0002009_preneoplasia0.99359270
82MP0004087_abnormal_muscle_fiber0.98930998
83MP0002092_abnormal_eye_morphology0.98258725
84MP0000537_abnormal_urethra_morphology0.97821099
85MP0002405_respiratory_system_inflammati0.97123642
86MP0003091_abnormal_cell_migration0.96822394
87MP0003221_abnormal_cardiomyocyte_apopto0.96737501
88MP0009672_abnormal_birth_weight0.96690443
89MP0002723_abnormal_immune_serum0.96598605
90MP0003115_abnormal_respiratory_system0.95930682
91MP0000313_abnormal_cell_death0.94640005
92MP0004264_abnormal_extraembryonic_tissu0.94503288
93MP0005174_abnormal_tail_pigmentation0.94379119
94MP0002249_abnormal_larynx_morphology0.93811357
95MP0005671_abnormal_response_to0.93169257
96MP0010155_abnormal_intestine_physiology0.92842066
97MP0006138_congestive_heart_failure0.91911088
98MP0003935_abnormal_craniofacial_develop0.91707455
99MP0005375_adipose_tissue_phenotype0.90511553
100MP0002796_impaired_skin_barrier0.90134850
101MP0003123_paternal_imprinting0.89927187
102MP0004185_abnormal_adipocyte_glucose0.89828100
103MP0003950_abnormal_plasma_membrane0.89542533
104MP0003943_abnormal_hepatobiliary_system0.89269085
105MP0000371_diluted_coat_color0.87037527
106MP0003448_altered_tumor_morphology0.83391576
107MP0000266_abnormal_heart_morphology0.83278998
108MP0003942_abnormal_urinary_system0.82946800
109MP0001784_abnormal_fluid_regulation0.81792747
110MP0005384_cellular_phenotype0.81478880
111MP0000377_abnormal_hair_follicle0.80919337
112MP0001873_stomach_inflammation0.80187308
113MP0002089_abnormal_postnatal_growth/wei0.79965001
114MP0000747_muscle_weakness0.79942619
115MP0003453_abnormal_keratinocyte_physiol0.79420378
116MP0010030_abnormal_orbit_morphology0.78233554
117MP0005621_abnormal_cell_physiology0.77736380
118MP0000566_synostosis0.77627716
119MP0000432_abnormal_head_morphology0.77613798
120MP0002697_abnormal_eye_size0.77240785
121MP0003656_abnormal_erythrocyte_physiolo0.77085232
122MP0005391_vision/eye_phenotype0.76668385
123MP0010678_abnormal_skin_adnexa0.75532456
124MP0004130_abnormal_muscle_cell0.75051630
125MP0004947_skin_inflammation0.74475084
126MP0003861_abnormal_nervous_system0.70836758
127MP0001851_eye_inflammation0.70120544
128MP0004381_abnormal_hair_follicle0.69613565
129MP0003172_abnormal_lysosome_physiology0.67381515
130MP0000477_abnormal_intestine_morphology0.66920986
131MP0000462_abnormal_digestive_system0.66807615
132MP0001614_abnormal_blood_vessel0.66057816
133MP0003315_abnormal_perineum_morphology0.64700790

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.37491296
2Volvulus (HP:0002580)3.40251937
3Long eyelashes (HP:0000527)3.17029897
4Short 4th metacarpal (HP:0010044)2.99587832
5Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.99587832
6Ependymoma (HP:0002888)2.79287986
7Ankyloglossia (HP:0010296)2.77919898
8Abnormality of the distal phalanx of the thumb (HP:0009617)2.68853826
9Increased nuchal translucency (HP:0010880)2.68486939
10Broad face (HP:0000283)2.66899215
11Flat acetabular roof (HP:0003180)2.60659394
12Trigonocephaly (HP:0000243)2.59635233
13Papillary thyroid carcinoma (HP:0002895)2.58713594
14Heterotopia (HP:0002282)2.57751969
15Hyperacusis (HP:0010780)2.57035376
16Astrocytoma (HP:0009592)2.53155481
17Abnormality of the astrocytes (HP:0100707)2.53155481
18Macroorchidism (HP:0000053)2.49976125
19Urethral obstruction (HP:0000796)2.47417380
20Dysmetric saccades (HP:0000641)2.43212153
21Metaphyseal cupping (HP:0003021)2.38274750
22Cerebral aneurysm (HP:0004944)2.36852644
23Recurrent viral infections (HP:0004429)2.34440228
24Prominent nose (HP:0000448)2.34077423
25Narrow palate (HP:0000189)2.29293801
26Germ cell neoplasia (HP:0100728)2.27444260
27Anal stenosis (HP:0002025)2.25723058
28Asymmetry of the thorax (HP:0001555)2.24228058
29Abnormality of oral frenula (HP:0000190)2.23074784
30Proximal placement of thumb (HP:0009623)2.22142632
31Neonatal hypoglycemia (HP:0001998)2.20554690
32Abnormality of the 4th metacarpal (HP:0010012)2.20142549
33Cutis marmorata (HP:0000965)2.19405358
34Deviation of the thumb (HP:0009603)2.19372651
35Obstructive sleep apnea (HP:0002870)2.15698276
36Glioma (HP:0009733)2.15551021
37Spinal cord lesions (HP:0100561)2.15425439
38Syringomyelia (HP:0003396)2.15425439
39Neoplasm of the oral cavity (HP:0100649)2.12113612
40Difficulty running (HP:0009046)2.10623426
41Ulnar bowing (HP:0003031)2.10052367
42High anterior hairline (HP:0009890)2.07048611
43Congenital stationary night blindness (HP:0007642)2.06936571
44Broad thumb (HP:0011304)2.06287192
45Arterial tortuosity (HP:0005116)2.05702789
46Subaortic stenosis (HP:0001682)2.05007683
47Abnormality of the left ventricular outflow tract (HP:0011103)2.05007683
48Medulloblastoma (HP:0002885)2.04743570
49Ectopic kidney (HP:0000086)2.03961930
50Absent frontal sinuses (HP:0002688)2.02528042
51Disproportionate tall stature (HP:0001519)2.02190517
52Malignant gastrointestinal tract tumors (HP:0006749)2.01797316
53Gastrointestinal carcinoma (HP:0002672)2.01797316
54Supernumerary ribs (HP:0005815)2.00717271
55Pseudobulbar signs (HP:0002200)2.00714075
56Abnormality of the calcaneus (HP:0008364)1.99934499
57Missing ribs (HP:0000921)1.99255500
58Eczematoid dermatitis (HP:0000976)1.99057807
59Obsessive-compulsive behavior (HP:0000722)1.96720512
60Mitral valve prolapse (HP:0001634)1.96330696
61Skin tags (HP:0010609)1.95195670
62Shallow orbits (HP:0000586)1.94829630
63Colitis (HP:0002583)1.94604188
64Low anterior hairline (HP:0000294)1.94403244
65Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.94058531
66Deep philtrum (HP:0002002)1.93268652
67Truncal obesity (HP:0001956)1.92751678
68Cellulitis (HP:0100658)1.92392706
69Acute myeloid leukemia (HP:0004808)1.92176747
70Lip pit (HP:0100267)1.91998195
71Elfin facies (HP:0004428)1.90192075
72Renal duplication (HP:0000075)1.89400863
73Hematochezia (HP:0002573)1.88960777
74Basal cell carcinoma (HP:0002671)1.88577082
75Limited elbow extension (HP:0001377)1.88528248
76Bladder neoplasm (HP:0009725)1.87959511
77Hepatoblastoma (HP:0002884)1.87921320
78Aortic aneurysm (HP:0004942)1.87549874
79Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.87207263
80Arnold-Chiari malformation (HP:0002308)1.87170928
81Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.86554827
82Short 1st metacarpal (HP:0010034)1.86554827
83Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.86434441
84Recurrent fungal infections (HP:0002841)1.86420226
85Sandal gap (HP:0001852)1.85684975
86Deep palmar crease (HP:0006191)1.85199202
87Increased density of long bones (HP:0006392)1.84022883
88Renovascular hypertension (HP:0100817)1.81298489
89Termporal pattern (HP:0011008)1.80722789
90Insidious onset (HP:0003587)1.80722789
91Selective tooth agenesis (HP:0001592)1.79851613
92Centrally nucleated skeletal muscle fibers (HP:0003687)1.79809069
93Abnormal vertebral ossification (HP:0100569)1.79792159
94Abnormality of chromosome segregation (HP:0002916)1.78950134
95Colon cancer (HP:0003003)1.76887477
96Dislocated radial head (HP:0003083)1.76784621
97Abnormal number of incisors (HP:0011064)1.76620193
98Abnormality of the nasal septum (HP:0000419)1.76323197
99Acute lymphatic leukemia (HP:0006721)1.75693060
100Bony spicule pigmentary retinopathy (HP:0007737)1.74863325
101Large earlobe (HP:0009748)1.74525427
102Transitional cell carcinoma of the bladder (HP:0006740)1.73761589
103Short phalanx of the thumb (HP:0009660)1.73419686
104Broad palm (HP:0001169)1.73056042
105Supernumerary bones of the axial skeleton (HP:0009144)1.72745471
106Neoplasm of striated muscle (HP:0009728)1.72724909
107T lymphocytopenia (HP:0005403)1.72697793
108Agammaglobulinemia (HP:0004432)1.72689851
109Panhypogammaglobulinemia (HP:0003139)1.72689577
110Thyroiditis (HP:0100646)1.72666921
111Leiomyosarcoma (HP:0100243)1.71473902
112Uterine leiomyosarcoma (HP:0002891)1.71473902
113Abnormal delayed hypersensitivity skin test (HP:0002963)1.71354463
114Thick eyebrow (HP:0000574)1.70601310
115Relative macrocephaly (HP:0004482)1.70522348
116Vertebral arch anomaly (HP:0008438)1.69600271
117High pitched voice (HP:0001620)1.68865852
118Sparse lateral eyebrow (HP:0005338)1.68502981
119Depressed nasal tip (HP:0000437)1.68129251
120Vascular tortuosity (HP:0004948)1.67544164
121Osteolytic defects of the hand bones (HP:0009699)1.67410106
122Osteolytic defects of the phalanges of the hand (HP:0009771)1.67410106
123Bowel incontinence (HP:0002607)1.66918129
124Abnormality of the salivary glands (HP:0010286)1.66848310
125Intestinal fistula (HP:0100819)1.66494299
126Subacute progressive viral hepatitis (HP:0006572)1.65921754
127Skull defect (HP:0001362)1.65783591
128Overgrowth (HP:0001548)1.65712846
129Broad phalanges of the hand (HP:0009768)1.65609657
130Abnormality of the intervertebral disk (HP:0005108)1.65184464
131Cubitus valgus (HP:0002967)1.64206225
132Viral hepatitis (HP:0006562)1.63694140
133IgM deficiency (HP:0002850)1.63067605
134Bicuspid aortic valve (HP:0001647)1.62631714
135Spontaneous hematomas (HP:0007420)1.62568098
136Advanced eruption of teeth (HP:0006288)1.62324779
137Abnormality of the radial head (HP:0003995)1.61450677
138Turricephaly (HP:0000262)1.60070940
139Abnormal foot bone ossification (HP:0010675)1.58976066
140Preauricular skin tag (HP:0000384)1.58778138
141Gastrointestinal inflammation (HP:0004386)1.58560444
142Long palpebral fissure (HP:0000637)1.58348069
143Inflammation of the large intestine (HP:0002037)1.56466500
144Papilloma (HP:0012740)1.56303018
145Verrucae (HP:0200043)1.56303018
146Nephroblastoma (Wilms tumor) (HP:0002667)1.56194428
147Abnormality of T cell number (HP:0011839)1.55201455
148Pendular nystagmus (HP:0012043)1.55001684
149Bladder carcinoma (HP:0002862)1.54813379
150Abnormality of the parietal bone (HP:0002696)1.54618499
151Curly hair (HP:0002212)1.53581397
152Persistence of primary teeth (HP:0006335)1.53119566
153Renal cell carcinoma (HP:0005584)1.53106004
154Abnormality of the thoracic spine (HP:0100711)1.52222793
155Thin ribs (HP:0000883)1.48767907
156Increased connective tissue (HP:0009025)1.47804433
157Abnormal large intestine physiology (HP:0012700)1.47778184
158Pointed chin (HP:0000307)1.45517156
159Dilatation of the ascending aorta (HP:0005111)1.44018477
160Precocious puberty (HP:0000826)1.43825992

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.12763746
2EEF2K3.56470580
3MAP3K103.51872017
4SMG13.11706933
5BRD43.03909600
6MAP4K12.57089819
7PRPF4B2.53293363
8NEK22.40499073
9CAMK1D2.21851502
10CAMK1G2.19933405
11CDC71.97394198
12TRIB31.92042610
13PKN21.90760193
14STK101.88881526
15CDK61.80957764
16ICK1.58372689
17RIPK41.52503652
18SIK21.52143674
19MTOR1.48600621
20CDK41.41131023
21CSF1R1.39304251
22FGFR31.37724019
23KSR21.37083342
24TTN1.36359832
25PTK61.35612678
26YES11.35424138
27RPS6KB21.34933107
28ALK1.29972603
29MAP3K131.21967859
30DMPK1.21949452
31WNK11.17440028
32ATR1.17251331
33GRK61.16299491
34STK41.15960154
35TYK21.12129979
36LATS11.12083290
37STK31.11914695
38RET1.10513132
39LATS21.06555862
40CDK91.06042626
41TTK1.04821469
42SGK21.03387316
43SIK11.02457091
44SCYL21.02391645
45RPS6KA41.00876889
46PAK40.99381958
47MAP3K20.98952799
48NLK0.97163711
49TGFBR20.96588717
50RIPK10.96485720
51CHEK10.95801365
52JAK10.94103097
53PIM10.93635053
54CHUK0.92774030
55CDK70.92085802
56SGK30.91245597
57MAP3K60.88241573
58ERN10.88134212
59PDGFRA0.87902959
60JAK30.87166297
61HCK0.85091568
62LRRK20.84864528
63EPHB10.82061114
64BTK0.81917911
65MELK0.81658305
66PDGFRB0.81077042
67KSR10.80761722
68FGFR20.78985813
69CDK20.78376174
70CSK0.78244199
71ATM0.77921497
72PASK0.77268891
73MAP3K70.76075408
74KIT0.73915618
75MAP3K140.72636753
76MAP3K80.72627573
77PNCK0.71501826
78ZAP700.70842629
79ERBB30.69662581
80HIPK20.69620480
81TYRO30.69153133
82TAF10.66286650
83NEK10.65822656
84FLT30.65534135
85BMX0.64992377
86PAK20.63748540
87MKNK10.62783852
88SGK4940.62542554
89SGK2230.62542554
90MAP3K10.62434301
91RPS6KC10.62245402
92RPS6KL10.62245402
93CDC42BPA0.61966182
94CSNK1D0.61563013
95AKT30.61552080
96MAPK100.59947675
97NEK90.59816493
98STK240.58587325
99TSSK60.58473112
100MAP2K30.58467236
101CLK10.57822018
102CHEK20.56795441
103FGFR40.56769714
104ITK0.56652925
105MAPK140.56215262
106CAMK40.55543152
107FGR0.54984723
108FGFR10.53429084
109BLK0.53125285
110MAPK10.52788949
111NUAK10.52323183
112RPS6KB10.52277643
113RPS6KA20.52209641
114TAOK10.51860874
115CDK10.50669421
116NTRK10.49865000
117LCK0.49856259
118MAPK70.49614395
119FES0.48322557
120JAK20.46810770
121AURKB0.46737717
122TRPM70.46575962
123TNK20.46332903
124PRKD20.46283108
125SYK0.45491063
126MATK0.44126691
127IRAK20.44013675
128PRKDC0.43562588
129TGFBR10.42873840
130DYRK1B0.42766017
131TXK0.42761458
132PLK10.42088279
133MARK20.41999972
134MKNK20.41564485
135GSK3B0.41437207
136RAF10.40316496
137PDPK10.38836723
138IRAK10.38615712
139MAP2K20.38024622

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.15247927
2Lysine degradation_Homo sapiens_hsa003101.99535899
3B cell receptor signaling pathway_Homo sapiens_hsa046621.99199178
4Chronic myeloid leukemia_Homo sapiens_hsa052201.88801182
5Primary immunodeficiency_Homo sapiens_hsa053401.80659202
6Notch signaling pathway_Homo sapiens_hsa043301.76679828
7Phototransduction_Homo sapiens_hsa047441.69775001
8Non-homologous end-joining_Homo sapiens_hsa034501.65187485
9mTOR signaling pathway_Homo sapiens_hsa041501.63188094
10mRNA surveillance pathway_Homo sapiens_hsa030151.62185012
11MicroRNAs in cancer_Homo sapiens_hsa052061.53878900
12Small cell lung cancer_Homo sapiens_hsa052221.52176400
13ErbB signaling pathway_Homo sapiens_hsa040121.51205250
14Cell cycle_Homo sapiens_hsa041101.46986307
15Transcriptional misregulation in cancer_Homo sapiens_hsa052021.45518958
16Adherens junction_Homo sapiens_hsa045201.43953679
17Acute myeloid leukemia_Homo sapiens_hsa052211.41105607
18Thyroid hormone signaling pathway_Homo sapiens_hsa049191.39962991
19Non-small cell lung cancer_Homo sapiens_hsa052231.38265735
20Herpes simplex infection_Homo sapiens_hsa051681.37083414
21Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.36534206
22NF-kappa B signaling pathway_Homo sapiens_hsa040641.35584951
23Mismatch repair_Homo sapiens_hsa034301.32783806
24Colorectal cancer_Homo sapiens_hsa052101.31285451
25Osteoclast differentiation_Homo sapiens_hsa043801.30849483
26DNA replication_Homo sapiens_hsa030301.29516140
27RNA transport_Homo sapiens_hsa030131.28942942
28Base excision repair_Homo sapiens_hsa034101.25848299
29Antigen processing and presentation_Homo sapiens_hsa046121.25569631
30Spliceosome_Homo sapiens_hsa030401.25097027
31Viral myocarditis_Homo sapiens_hsa054161.24869561
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.23908957
33Pancreatic cancer_Homo sapiens_hsa052121.21303840
34HTLV-I infection_Homo sapiens_hsa051661.20663087
35T cell receptor signaling pathway_Homo sapiens_hsa046601.18324289
36Endometrial cancer_Homo sapiens_hsa052131.15768761
37Proteoglycans in cancer_Homo sapiens_hsa052051.15607376
38Viral carcinogenesis_Homo sapiens_hsa052031.15040883
39Leishmaniasis_Homo sapiens_hsa051401.13946699
40Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.11757306
41Measles_Homo sapiens_hsa051621.09123859
42Dorso-ventral axis formation_Homo sapiens_hsa043201.08378748
43Toxoplasmosis_Homo sapiens_hsa051451.07259266
44Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.06935498
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.06810273
46Neurotrophin signaling pathway_Homo sapiens_hsa047221.04787475
47Estrogen signaling pathway_Homo sapiens_hsa049151.04243085
48Hepatitis B_Homo sapiens_hsa051611.03897799
49Prostate cancer_Homo sapiens_hsa052151.01125100
50Long-term potentiation_Homo sapiens_hsa047200.98256779
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.97631040
52p53 signaling pathway_Homo sapiens_hsa041150.95936354
53Basal cell carcinoma_Homo sapiens_hsa052170.95620946
54Bladder cancer_Homo sapiens_hsa052190.94767903
55Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.94552942
56Platelet activation_Homo sapiens_hsa046110.93792428
57GnRH signaling pathway_Homo sapiens_hsa049120.92841722
58Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92610741
59FoxO signaling pathway_Homo sapiens_hsa040680.91197299
60Hepatitis C_Homo sapiens_hsa051600.90737216
61Insulin resistance_Homo sapiens_hsa049310.90488542
62Influenza A_Homo sapiens_hsa051640.90472821
63Amoebiasis_Homo sapiens_hsa051460.90445320
64Pathways in cancer_Homo sapiens_hsa052000.90190245
65Focal adhesion_Homo sapiens_hsa045100.89658327
66Apoptosis_Homo sapiens_hsa042100.89363957
67Hippo signaling pathway_Homo sapiens_hsa043900.88181921
68Glioma_Homo sapiens_hsa052140.87919035
69Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.87439109
70Chemokine signaling pathway_Homo sapiens_hsa040620.86773173
71Jak-STAT signaling pathway_Homo sapiens_hsa046300.86197463
72Longevity regulating pathway - mammal_Homo sapiens_hsa042110.85405506
73One carbon pool by folate_Homo sapiens_hsa006700.84945695
74Renal cell carcinoma_Homo sapiens_hsa052110.84925135
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.84554831
76TGF-beta signaling pathway_Homo sapiens_hsa043500.83729011
77Hematopoietic cell lineage_Homo sapiens_hsa046400.83558538
78Intestinal immune network for IgA production_Homo sapiens_hsa046720.83178153
79Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.83137971
80Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81008047
81Epstein-Barr virus infection_Homo sapiens_hsa051690.80944919
82Regulation of actin cytoskeleton_Homo sapiens_hsa048100.80652028
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.79420534
84Central carbon metabolism in cancer_Homo sapiens_hsa052300.76907236
85Toll-like receptor signaling pathway_Homo sapiens_hsa046200.76504774
86Fanconi anemia pathway_Homo sapiens_hsa034600.76021776
87Tight junction_Homo sapiens_hsa045300.74534170
88Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.73446559
89Melanogenesis_Homo sapiens_hsa049160.71015718
90Thyroid cancer_Homo sapiens_hsa052160.70977559
91NOD-like receptor signaling pathway_Homo sapiens_hsa046210.69390213
92Inositol phosphate metabolism_Homo sapiens_hsa005620.68792350
93VEGF signaling pathway_Homo sapiens_hsa043700.68220170
94TNF signaling pathway_Homo sapiens_hsa046680.67620337
95Melanoma_Homo sapiens_hsa052180.67398520
96Wnt signaling pathway_Homo sapiens_hsa043100.66638244
97MAPK signaling pathway_Homo sapiens_hsa040100.66445559
98Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.66030549
99AMPK signaling pathway_Homo sapiens_hsa041520.65951393
100Gap junction_Homo sapiens_hsa045400.65529150
101Type II diabetes mellitus_Homo sapiens_hsa049300.65484372
102RNA degradation_Homo sapiens_hsa030180.65477524
103Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.65472991
104HIF-1 signaling pathway_Homo sapiens_hsa040660.65373028
105Prolactin signaling pathway_Homo sapiens_hsa049170.65132867
106Fatty acid biosynthesis_Homo sapiens_hsa000610.63566659
107Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.62613819
108Adipocytokine signaling pathway_Homo sapiens_hsa049200.62085072
109Choline metabolism in cancer_Homo sapiens_hsa052310.60369396
110Homologous recombination_Homo sapiens_hsa034400.60293140
111Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60176142
112Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.58845479
113Hedgehog signaling pathway_Homo sapiens_hsa043400.57486861
114Insulin signaling pathway_Homo sapiens_hsa049100.56418216
115Rap1 signaling pathway_Homo sapiens_hsa040150.56148658
116Shigellosis_Homo sapiens_hsa051310.56126569
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.56100282
118RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.55399580
119Glucagon signaling pathway_Homo sapiens_hsa049220.55074430
120Thyroid hormone synthesis_Homo sapiens_hsa049180.54577437
121Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54467271
122Other glycan degradation_Homo sapiens_hsa005110.54110754
123Tuberculosis_Homo sapiens_hsa051520.53897379
124Long-term depression_Homo sapiens_hsa047300.52460929
125cGMP-PKG signaling pathway_Homo sapiens_hsa040220.51261104
126Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.50850231

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