KEL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1heme metabolic process (GO:0042168)9.91531936
2erythrocyte maturation (GO:0043249)9.52859323
3hemoglobin metabolic process (GO:0020027)7.47765652
4erythrocyte development (GO:0048821)6.95280206
5response to methylmercury (GO:0051597)6.60963744
6tetrapyrrole metabolic process (GO:0033013)6.51838503
7negative regulation of erythrocyte differentiation (GO:0045647)6.08348534
8pigment biosynthetic process (GO:0046148)5.95951424
9response to lead ion (GO:0010288)5.85609785
10response to insecticide (GO:0017085)5.63095476
11DNA topological change (GO:0006265)5.24358217
12erythrocyte differentiation (GO:0030218)5.21476242
13one-carbon compound transport (GO:0019755)5.02807993
14pigment metabolic process (GO:0042440)4.94383173
15myeloid cell development (GO:0061515)4.52168258
16regulation of response to osmotic stress (GO:0047484)4.18089138
17DNA replication initiation (GO:0006270)4.16813190
18iron ion import (GO:0097286)4.15240615
19regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.12155609
20positive regulation of megakaryocyte differentiation (GO:0045654)4.04304325
21response to arsenic-containing substance (GO:0046685)4.01976066
22bicarbonate transport (GO:0015701)3.90821041
23DNA strand elongation involved in DNA replication (GO:0006271)3.90659909
24megakaryocyte development (GO:0035855)3.88173822
25gas transport (GO:0015669)3.83953298
26antibacterial humoral response (GO:0019731)3.83940899
27nuclear pore complex assembly (GO:0051292)3.83578351
28innate immune response in mucosa (GO:0002227)3.82789932
29telomere maintenance via semi-conservative replication (GO:0032201)3.81571791
30DNA replication checkpoint (GO:0000076)3.80115663
31mitotic sister chromatid segregation (GO:0000070)3.75619095
32DNA strand elongation (GO:0022616)3.73569830
33embryonic hemopoiesis (GO:0035162)3.70572928
34regulation of RNA export from nucleus (GO:0046831)3.67146576
35positive regulation of granulocyte differentiation (GO:0030854)3.65615634
36protein localization to chromosome, centromeric region (GO:0071459)3.59364670
37DNA unwinding involved in DNA replication (GO:0006268)3.59139729
38positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)3.54422413
39cofactor biosynthetic process (GO:0051188)3.50699531
40very-low-density lipoprotein particle assembly (GO:0034379)3.50245545
41regulation of histone H3-K4 methylation (GO:0051569)3.49675539
42folic acid-containing compound biosynthetic process (GO:0009396)3.47569561
43ribosomal small subunit assembly (GO:0000028)3.47079906
44antimicrobial humoral response (GO:0019730)3.46435452
45glycine transport (GO:0015816)3.44444000
46kinetochore organization (GO:0051383)3.44043787
47sister chromatid segregation (GO:0000819)3.42480229
48mitotic chromosome condensation (GO:0007076)3.38107682
49cellular response to thyroid hormone stimulus (GO:0097067)3.30318540
50DNA replication-dependent nucleosome assembly (GO:0006335)3.29820909
51DNA replication-dependent nucleosome organization (GO:0034723)3.29820909
52nuclear pore organization (GO:0006999)3.28580765
53protein localization to kinetochore (GO:0034501)3.28536730
54hematopoietic stem cell differentiation (GO:0060218)3.25621303
55platelet formation (GO:0030220)3.25458080
56protein autoprocessing (GO:0016540)3.22463893
57proline biosynthetic process (GO:0006561)3.22053099
58negative regulation of viral entry into host cell (GO:0046597)3.18016007
59potassium ion export (GO:0071435)3.17611884
60L-alpha-amino acid transmembrane transport (GO:1902475)3.17310432
61positive regulation of B cell differentiation (GO:0045579)3.15271347
62viral transcription (GO:0019083)3.14330646
63telomere maintenance via recombination (GO:0000722)3.14196797
64CENP-A containing nucleosome assembly (GO:0034080)3.13719134
65granulocyte differentiation (GO:0030851)3.13222268
66protein-cofactor linkage (GO:0018065)3.11515073
67attachment of spindle microtubules to kinetochore (GO:0008608)3.04713177
68regulation of cytokine secretion involved in immune response (GO:0002739)3.02501836
69translational termination (GO:0006415)3.02098824
70heme transport (GO:0015886)3.00667262
71deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.00647413
72regulation of nucleobase-containing compound transport (GO:0032239)2.98811001
73mucosal immune response (GO:0002385)2.98045404
74response to thyroid hormone (GO:0097066)2.97163656
75positive regulation of chromosome segregation (GO:0051984)2.96991359
76nucleosome assembly (GO:0006334)2.96015418
77mitotic recombination (GO:0006312)2.94846761
78chromatin remodeling at centromere (GO:0031055)2.94115090
79DNA replication-independent nucleosome organization (GO:0034724)2.92160015
80DNA replication-independent nucleosome assembly (GO:0006336)2.92160015
81kinetochore assembly (GO:0051382)2.91716606
82regulation of DNA endoreduplication (GO:0032875)2.91030897
83positive regulation of erythrocyte differentiation (GO:0045648)2.89675112
84plasma lipoprotein particle assembly (GO:0034377)2.87057424
85negative regulation of histone methylation (GO:0031061)2.86722634
86actin filament capping (GO:0051693)2.85354895
87pore complex assembly (GO:0046931)2.84373613
88disruption of cells of other organism (GO:0044364)2.84189219
89killing of cells of other organism (GO:0031640)2.84189219
90regulation of erythrocyte differentiation (GO:0045646)2.82991831
91defense response to fungus (GO:0050832)2.82500060
92negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.82137882
93regulation of histone H3-K9 methylation (GO:0051570)2.81346867
94translational elongation (GO:0006414)2.80281651
95DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.78313437
96chromatin assembly or disassembly (GO:0006333)2.78195322
97meiotic chromosome segregation (GO:0045132)2.72964047
98regulation of translational fidelity (GO:0006450)2.70633455
99mitotic nuclear envelope disassembly (GO:0007077)2.70528015
100organ or tissue specific immune response (GO:0002251)2.69501158
101intracellular estrogen receptor signaling pathway (GO:0030520)2.69397311
102purine-containing compound salvage (GO:0043101)2.64879405
103chromosome segregation (GO:0007059)2.63407214
104Peyers patch development (GO:0048541)2.63301536
105mucosal-associated lymphoid tissue development (GO:0048537)2.63301536
106microtubule depolymerization (GO:0007019)2.63198017
107hemopoiesis (GO:0030097)2.62026241
108water-soluble vitamin biosynthetic process (GO:0042364)2.61875110
109regulation of histone H3-K27 methylation (GO:0061085)2.61775951
110protein-DNA complex assembly (GO:0065004)2.61539435
111nucleosome organization (GO:0034728)2.60201300
112homocysteine metabolic process (GO:0050667)2.59126892
113deoxyribonucleotide biosynthetic process (GO:0009263)2.58857701
114definitive hemopoiesis (GO:0060216)2.56854058
115telomere maintenance via telomere lengthening (GO:0010833)2.56577248
116positive regulation of histone methylation (GO:0031062)2.55811894
117DNA damage response, signal transduction resulting in transcription (GO:0042772)2.54513794
118regulation of histone methylation (GO:0031060)2.54489890
119SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.53192034
120regulation of natural killer cell differentiation (GO:0032823)2.51939668
121IMP biosynthetic process (GO:0006188)2.51497650
122membrane disassembly (GO:0030397)2.51244615
123nuclear envelope disassembly (GO:0051081)2.51244615
124regulation of exit from mitosis (GO:0007096)2.50053792
125nucleotide-excision repair, DNA gap filling (GO:0006297)2.49226678
126hydrogen peroxide catabolic process (GO:0042744)2.48294302
127poly(A)+ mRNA export from nucleus (GO:0016973)2.48229565
128cellular protein complex disassembly (GO:0043624)2.47659271
129cotranslational protein targeting to membrane (GO:0006613)2.47311478
130protein targeting to ER (GO:0045047)2.47076150
131histone exchange (GO:0043486)2.46893095
1323-UTR-mediated mRNA stabilization (GO:0070935)2.46798854
133iron ion homeostasis (GO:0055072)2.46121785
134translational initiation (GO:0006413)2.45606296
135translesion synthesis (GO:0019985)2.44750886
136nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.44672154
137DNA ligation (GO:0006266)2.42661195
138negative regulation of bone mineralization (GO:0030502)2.42343008
139negative regulation of fatty acid biosynthetic process (GO:0045717)2.40891373
140negative regulation of potassium ion transmembrane transport (GO:1901380)2.39764001
141protein export from nucleus (GO:0006611)2.39665615
142protoporphyrinogen IX metabolic process (GO:0046501)18.6354088
143protoporphyrinogen IX biosynthetic process (GO:0006782)17.6298068
144porphyrin-containing compound biosynthetic process (GO:0006779)12.6421760
145heme biosynthetic process (GO:0006783)12.6090031
146tetrapyrrole biosynthetic process (GO:0033014)11.2869273
147oxygen transport (GO:0015671)10.9422095
148porphyrin-containing compound metabolic process (GO:0006778)10.0448318

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.78003210
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse6.18851137
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.86389961
4GATA1_22025678_ChIP-Seq_K562_Human4.63171665
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.71602619
6* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse3.35086388
7* GATA1_19941826_ChIP-Seq_K562_Human3.31376547
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.96770676
9* GATA1_19941827_ChIP-Seq_MEL_Mouse2.95682339
10* KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse2.92748266
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.92639080
12MYC_18555785_ChIP-Seq_MESCs_Mouse2.74318063
13SCL_19346495_ChIP-Seq_HPC-7_Human2.59103293
14GATA1_22383799_ChIP-Seq_G1ME_Mouse2.35336080
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.04436738
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.02378686
17E2F1_21310950_ChIP-Seq_MCF-7_Human1.97869923
18CREB1_15753290_ChIP-ChIP_HEK293T_Human1.93383581
19TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.91289945
20EST1_17652178_ChIP-ChIP_JURKAT_Human1.89856640
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.88000786
22ETS1_20019798_ChIP-Seq_JURKAT_Human1.85718056
23MYC_19030024_ChIP-ChIP_MESCs_Mouse1.85568927
24AR_21909140_ChIP-Seq_LNCAP_Human1.84917818
25* GATA2_19941826_ChIP-Seq_K562_Human1.79071350
26ELF1_17652178_ChIP-ChIP_JURKAT_Human1.75419500
27VDR_23849224_ChIP-Seq_CD4+_Human1.72472983
28NELFA_20434984_ChIP-Seq_ESCs_Mouse1.70308122
29MYC_19079543_ChIP-ChIP_MESCs_Mouse1.68515043
30MYC_22102868_ChIP-Seq_BL_Human1.67304565
31SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.65467199
32THAP11_20581084_ChIP-Seq_MESCs_Mouse1.64583967
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.60547321
34XRN2_22483619_ChIP-Seq_HELA_Human1.60273060
35GABP_17652178_ChIP-ChIP_JURKAT_Human1.56865809
36ZNF263_19887448_ChIP-Seq_K562_Human1.54589947
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.52221281
38HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.49858792
39HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.47102460
40VDR_21846776_ChIP-Seq_THP-1_Human1.46664170
41ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.43033911
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.42179427
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.41411756
44FOXP3_21729870_ChIP-Seq_TREG_Human1.41319003
45DCP1A_22483619_ChIP-Seq_HELA_Human1.40330941
46E2F1_18555785_ChIP-Seq_MESCs_Mouse1.39836521
47ERG_20887958_ChIP-Seq_HPC-7_Mouse1.39496426
48NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.39483155
49SRF_21415370_ChIP-Seq_HL-1_Mouse1.35933885
50MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.35452699
51CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.32031680
52HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.27774420
53TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25964764
54* SPI1_23127762_ChIP-Seq_K562_Human1.25809224
55CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.24955123
56CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.24487652
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.23553971
58GATA2_22383799_ChIP-Seq_G1ME_Mouse1.22563550
59* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21967341
60GABP_19822575_ChIP-Seq_HepG2_Human1.21634379
61PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.20856650
62POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.19730861
63PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.19611771
64KDM5A_27292631_Chip-Seq_BREAST_Human1.19272583
65FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.19187615
66ZFX_18555785_ChIP-Seq_MESCs_Mouse1.16387139
67E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.13836333
68MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13192740
69TTF2_22483619_ChIP-Seq_HELA_Human1.12959938
70CIITA_25753668_ChIP-Seq_RAJI_Human1.12945331
71ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10952722
72CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.09641641
73CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.08091774
74ELK1_19687146_ChIP-ChIP_HELA_Human1.05805125
75GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.05727385
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.04961839
77CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.04436620
78NCOR1_26117541_ChIP-Seq_K562_Human1.04070790
79ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.03269810
80KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.02932214
81SPI1_23547873_ChIP-Seq_NB4_Human1.02130503
82PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02062556
83EGR1_19374776_ChIP-ChIP_THP-1_Human1.01559368
84SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00756337
85MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.99029525
86FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.98617875
87TFEB_21752829_ChIP-Seq_HELA_Human0.98581061
88PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.98468627
89SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.98313035
90LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.97252009
91CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95841698
92SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.95052805
93EGR1_23403033_ChIP-Seq_LIVER_Mouse0.94553875
94MYB_21317192_ChIP-Seq_ERMYB_Mouse0.94234904
95SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.94205052
96CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.94200503
97KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.93777043
98UTX_26944678_Chip-Seq_JUKART_Human0.92825926
99MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.91895245
100RUNX1_22412390_ChIP-Seq_EML_Mouse0.91419444
101RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.90811064
102LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.90703012
103CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.90226785
104HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.87222012
105ELF1_20517297_ChIP-Seq_JURKAT_Human0.86913755
106CTCF_27219007_Chip-Seq_ERYTHROID_Human0.86799087
107YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.86650241
108ETS1_22383799_ChIP-Seq_G1ME_Mouse0.86411819
109TCF7_22412390_ChIP-Seq_EML_Mouse0.86073893
110PADI4_21655091_ChIP-ChIP_MCF-7_Human0.84751410
111YY1_21170310_ChIP-Seq_MESCs_Mouse0.83836211
112BRD4_27068464_Chip-Seq_AML-cells_Mouse0.83582859
113MAF_26560356_Chip-Seq_TH1_Human0.82764652
114KLF4_18555785_ChIP-Seq_MESCs_Mouse0.82743089
115HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.82728743
116STAT3_1855785_ChIP-Seq_MESCs_Mouse0.82689648
117BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.81939992
118DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.81922547
119NANOG_18555785_ChIP-Seq_MESCs_Mouse0.81333500
120SOX2_16153702_ChIP-ChIP_HESCs_Human0.80879891

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003111_abnormal_nucleus_morphology3.59690608
2MP0008995_early_reproductive_senescence2.93248924
3MP0010094_abnormal_chromosome_stability2.81417155
4MP0001545_abnormal_hematopoietic_system2.78100796
5MP0005397_hematopoietic_system_phenotyp2.78100796
6MP0005083_abnormal_biliary_tract2.68102165
7MP0003693_abnormal_embryo_hatching2.62863709
8MP0009278_abnormal_bone_marrow2.55248327
9MP0003077_abnormal_cell_cycle2.38068003
10MP0008057_abnormal_DNA_replication2.16932621
11MP0005636_abnormal_mineral_homeostasis2.15604479
12MP0004957_abnormal_blastocyst_morpholog2.03467011
13MP0002396_abnormal_hematopoietic_system2.02123112
14MP0003656_abnormal_erythrocyte_physiolo11.6161639
15MP0004147_increased_porphyrin_level11.0172215
16MP0006054_spinal_hemorrhage1.89836927
17MP0005451_abnormal_body_composition1.70728421
18MP0003806_abnormal_nucleotide_metabolis1.65105438
19MP0006036_abnormal_mitochondrial_physio1.56205245
20MP0000490_abnormal_crypts_of1.52485733
21MP0009697_abnormal_copulation1.49876512
22MP0004145_abnormal_muscle_electrophysio1.47379778
23MP0008058_abnormal_DNA_repair1.46834663
24MP0003186_abnormal_redox_activity1.40732982
25MP0000372_irregular_coat_pigmentation1.38613383
26MP0002398_abnormal_bone_marrow1.38128709
27MP0010307_abnormal_tumor_latency1.36869338
28MP0003303_peritoneal_inflammation1.36680883
29MP0002132_abnormal_respiratory_system1.36089556
30MP0008775_abnormal_heart_ventricle1.32030705
31MP0008872_abnormal_physiological_respon1.24439972
32MP0005464_abnormal_platelet_physiology1.22588302
33MP0000350_abnormal_cell_proliferation1.20567754
34MP0002722_abnormal_immune_system1.19126101
35MP0000689_abnormal_spleen_morphology1.16798378
36MP0003172_abnormal_lysosome_physiology1.12281223
37MP0009333_abnormal_splenocyte_physiolog1.11974511
38MP0000313_abnormal_cell_death1.07297167
39MP0002429_abnormal_blood_cell1.04469027
40MP0008007_abnormal_cellular_replicative1.04258183
41MP0005075_abnormal_melanosome_morpholog1.03021849
42MP0000685_abnormal_immune_system0.99918582
43MP0009931_abnormal_skin_appearance0.99543765
44MP0005501_abnormal_skin_physiology0.97488399
45MP0000015_abnormal_ear_pigmentation0.96185794
46MP0001730_embryonic_growth_arrest0.96000958
47MP0002019_abnormal_tumor_incidence0.95892529
48MP0004808_abnormal_hematopoietic_stem0.94206336
49MP0008932_abnormal_embryonic_tissue0.92546862
50MP0008770_decreased_survivor_rate0.91534747
51MP0004215_abnormal_myocardial_fiber0.88647151
52MP0001529_abnormal_vocalization0.86682894
53MP0003718_maternal_effect0.85734981
54MP0002080_prenatal_lethality0.85283077
55MP0000749_muscle_degeneration0.79850181
56MP0002139_abnormal_hepatobiliary_system0.79680886
57MP0003191_abnormal_cellular_cholesterol0.77000934
58MP0000703_abnormal_thymus_morphology0.74668471
59MP0000609_abnormal_liver_physiology0.74500995
60MP0005671_abnormal_response_to0.73309503
61MP0003123_paternal_imprinting0.72871378
62MP0002086_abnormal_extraembryonic_tissu0.72827659
63MP0003890_abnormal_embryonic-extraembry0.72784459
64MP0002877_abnormal_melanocyte_morpholog0.72234247
65MP0008260_abnormal_autophagy0.71964353
66MP0001697_abnormal_embryo_size0.69032135
67MP0002095_abnormal_skin_pigmentation0.67590815
68MP0003221_abnormal_cardiomyocyte_apopto0.66910336
69MP0002009_preneoplasia0.64871453
70MP0000598_abnormal_liver_morphology0.64735530
71MP0009765_abnormal_xenobiotic_induced0.64728044
72MP0009764_decreased_sensitivity_to0.64689159
73MP0001873_stomach_inflammation0.63042356
74MP0001661_extended_life_span0.62481682
75MP0001727_abnormal_embryo_implantation0.62278118
76MP0001764_abnormal_homeostasis0.62128663
77MP0010352_gastrointestinal_tract_polyps0.61860331
78MP0003567_abnormal_fetal_cardiomyocyte0.61287614
79MP0005220_abnormal_exocrine_pancreas0.60889439
80MP0005025_abnormal_response_to0.60170808
81MP0000358_abnormal_cell_content/0.59668791
82MP0003786_premature_aging0.58402706
83MP0001672_abnormal_embryogenesis/_devel0.56738631
84MP0005380_embryogenesis_phenotype0.56738631
85MP0005085_abnormal_gallbladder_physiolo0.55561931
86MP0000678_abnormal_parathyroid_gland0.55076111
87MP0003984_embryonic_growth_retardation0.54732663
88MP0009763_increased_sensitivity_to0.54395073
89MP0008789_abnormal_olfactory_epithelium0.53680042
90MP0005384_cellular_phenotype0.53627612
91MP0008877_abnormal_DNA_methylation0.53109201
92MP0006035_abnormal_mitochondrial_morpho0.53079404
93MP0005058_abnormal_lysosome_morphology0.52341242
94MP0005621_abnormal_cell_physiology0.52036698
95MP0002210_abnormal_sex_determination0.52004206
96MP0005076_abnormal_cell_differentiation0.51918891
97MP0002088_abnormal_embryonic_growth/wei0.51440517
98MP0003698_abnormal_male_reproductive0.50867809
99MP0000716_abnormal_immune_system0.50827641
100MP0004197_abnormal_fetal_growth/weight/0.50467955
101MP0005647_abnormal_sex_gland0.49191144
102MP0002405_respiratory_system_inflammati0.47983349
103MP0001881_abnormal_mammary_gland0.46619734
104MP0009643_abnormal_urine_homeostasis0.45705202
105MP0002084_abnormal_developmental_patter0.45287376
106MP0005499_abnormal_olfactory_system0.45158571
107MP0005394_taste/olfaction_phenotype0.45158571
108MP0005584_abnormal_enzyme/coenzyme_acti0.44261637
109MP0002083_premature_death0.43602102
110MP0002419_abnormal_innate_immunity0.43441468
111MP0009703_decreased_birth_body0.42984751
112MP0001243_abnormal_dermal_layer0.42125462
113MP0005319_abnormal_enzyme/_coenzyme0.41875576
114MP0001784_abnormal_fluid_regulation0.40680710
115MP0003699_abnormal_female_reproductive0.40266708
116MP0002085_abnormal_embryonic_tissue0.39027634
117MP0000858_altered_metastatic_potential0.38775702
118MP0001145_abnormal_male_reproductive0.38741910
119MP0000266_abnormal_heart_morphology0.38169708
120MP0002166_altered_tumor_susceptibility0.37303215
121MP0001663_abnormal_digestive_system0.36104663
122MP0005376_homeostasis/metabolism_phenot0.35416186
123MP0005266_abnormal_metabolism0.35316392
124MP0004264_abnormal_extraembryonic_tissu0.34934080
125MP0009053_abnormal_anal_canal0.34868335
126MP0002970_abnormal_white_adipose0.34844123
127MP0002138_abnormal_hepatobiliary_system0.34682082
128MP0008873_increased_physiological_sensi0.33233211
129MP0008469_abnormal_protein_level0.32806866
130MP0001929_abnormal_gametogenesis0.31585447
131MP0000477_abnormal_intestine_morphology0.31541761
132MP0010771_integument_phenotype0.31513322
133MP0001191_abnormal_skin_condition0.30929333
134MP0000465_gastrointestinal_hemorrhage0.30825239
135MP0005360_urolithiasis0.30732399

Predicted human phenotypes

RankGene SetZ-score
1Acanthocytosis (HP:0001927)9.48185338
2Reticulocytosis (HP:0001923)8.49523084
3Hypochromic microcytic anemia (HP:0004840)8.37603860
4Abnormal hemoglobin (HP:0011902)6.58669410
5Diaphragmatic weakness (HP:0009113)6.45492914
6Abnormality of reticulocytes (HP:0004312)6.21364579
7Cholelithiasis (HP:0001081)6.21227517
8Paralysis (HP:0003470)5.98340958
9Abnormal number of erythroid precursors (HP:0012131)5.80052720
10Hyperbilirubinemia (HP:0002904)5.72731339
11Abnormal gallbladder morphology (HP:0012437)5.59333156
12Abnormality of cells of the erythroid lineage (HP:0012130)5.46267633
13Insomnia (HP:0100785)4.99740009
14Osteomalacia (HP:0002749)4.79333254
15Hypochromic anemia (HP:0001931)4.33638295
16Microcytic anemia (HP:0001935)4.17135990
17Cutaneous photosensitivity (HP:0000992)4.14864608
18Ileus (HP:0002595)3.96813211
19Abnormality of the gallbladder (HP:0005264)3.86566207
20Abnormal gallbladder physiology (HP:0012438)3.83966355
21Cholecystitis (HP:0001082)3.83966355
22Polycythemia (HP:0001901)3.66833459
23Birth length less than 3rd percentile (HP:0003561)3.56628505
24Increased serum ferritin (HP:0003281)3.38682214
25Truncus arteriosus (HP:0001660)3.35365827
26Petechiae (HP:0000967)3.16901304
27Abnormality of iron homeostasis (HP:0011031)3.03742892
28Hepatocellular carcinoma (HP:0001402)2.94751747
29Hyperthyroidism (HP:0000836)2.91887303
30Hyponatremia (HP:0002902)2.84735789
31Abnormality of transition element cation homeostasis (HP:0011030)2.79411428
32Hypoparathyroidism (HP:0000829)2.76939513
33Nausea (HP:0002018)2.75662103
34Macrocytic anemia (HP:0001972)2.72630931
35Homocystinuria (HP:0002156)2.71660809
36Abnormality of homocysteine metabolism (HP:0010919)2.71660809
37Pallor (HP:0000980)2.69047508
38Abnormality of the fingertips (HP:0001211)2.67637525
39Prolonged bleeding time (HP:0003010)2.66640956
40Abnormality of sodium homeostasis (HP:0010931)2.55563520
41Aplasia/Hypoplasia of the earlobes (HP:0009906)2.45915272
42Short middle phalanx of the 5th finger (HP:0004220)2.43858079
43Toxemia of pregnancy (HP:0100603)2.29064232
44Bowel incontinence (HP:0002607)2.23737672
45Global brain atrophy (HP:0002283)2.23331357
46Reticulocytopenia (HP:0001896)2.15749459
47Onycholysis (HP:0001806)2.15501455
48Abnormal large intestine physiology (HP:0012700)2.12826271
49Delusions (HP:0000746)2.12635565
50Confusion (HP:0001289)2.12227243
51Pustule (HP:0200039)2.08356166
52Urticaria (HP:0001025)2.07259176
53Nonimmune hydrops fetalis (HP:0001790)2.06416342
54Peripheral hypomyelination (HP:0007182)2.03711854
55Epistaxis (HP:0000421)2.00868894
56Acute myeloid leukemia (HP:0004808)2.00859715
57Abnormality of the heme biosynthetic pathway (HP:0010472)15.6065873
58Poikilocytosis (HP:0004447)12.8026178
59Cerebral palsy (HP:0100021)1.98403936
60Generalized hyperpigmentation (HP:0007440)1.97357005
61Orthostatic hypotension (HP:0001278)1.97039844
62Renal tubular acidosis (HP:0001947)1.92583506
63Hypertensive crisis (HP:0100735)1.90235444
64Hypoplasia of the capital femoral epiphysis (HP:0003090)1.85052709
65Pathologic fracture (HP:0002756)1.82238219
66Ventricular fibrillation (HP:0001663)1.80430120
67Chronic obstructive pulmonary disease (HP:0006510)1.79917209
68Obstructive lung disease (HP:0006536)1.79917209
69Ankyloglossia (HP:0010296)1.78474296
70Cortical dysplasia (HP:0002539)1.73417722
71Albinism (HP:0001022)1.73203784
72Lower limb hyperreflexia (HP:0002395)1.71707632
73Abnormality of cochlea (HP:0000375)1.70457742
74Gonadal dysgenesis (HP:0000133)1.69730482
75Breast hypoplasia (HP:0003187)1.61760324
76Basal cell carcinoma (HP:0002671)1.61757886
77Broad palm (HP:0001169)1.61010086
78Abnormal blistering of the skin (HP:0008066)1.60484196
79Neoplasm of head and neck (HP:0012288)1.56589089
80Esophageal neoplasm (HP:0100751)1.56589089
81Purpura (HP:0000979)1.54700402
82Aplastic anemia (HP:0001915)1.54307987
83Abnormal platelet function (HP:0011869)1.53579116
84Impaired platelet aggregation (HP:0003540)1.53579116
85Limb hypertonia (HP:0002509)1.51054020
86Gastrointestinal infarctions (HP:0005244)1.50675281
87Cafe-au-lait spot (HP:0000957)1.49773741
88Atelectasis (HP:0100750)1.49318415
89Abnormality of the tricuspid valve (HP:0001702)1.48935392
90Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.47168922
91Metaphyseal cupping (HP:0003021)1.45334733
92Duplicated collecting system (HP:0000081)1.45145578
93Multiple enchondromatosis (HP:0005701)1.44729351
94Bone marrow hypocellularity (HP:0005528)1.44373186
95Neoplasm of the liver (HP:0002896)1.43675011
96Small intestinal stenosis (HP:0012848)1.42773314
97Duodenal stenosis (HP:0100867)1.42773314
98Osteomyelitis (HP:0002754)1.42730565
99Myelodysplasia (HP:0002863)1.42624952
100Depression (HP:0000716)1.42530579
101Aplasia/Hypoplasia of the thymus (HP:0010515)1.41885199
102Absent epiphyses (HP:0010577)1.41794195
103Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.41794195
104Hypopigmented skin patches (HP:0001053)1.41461154
105Cortical visual impairment (HP:0100704)1.40157455
106Metabolic acidosis (HP:0001942)1.38212455
107Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.37399132
108Chromsome breakage (HP:0040012)1.36643330
109Abnormally folded helix (HP:0008544)1.35484436
110Autoimmune thrombocytopenia (HP:0001973)1.35044112
111Abnormality of chromosome stability (HP:0003220)1.34789216
112Progressive microcephaly (HP:0000253)1.34310008
113Splenomegaly (HP:0001744)1.34302249
114Pancreatic islet-cell hyperplasia (HP:0004510)1.33425575
115Upper limb muscle weakness (HP:0003484)1.33004426
116Irregular epiphyses (HP:0010582)1.32803508
117Hypertriglyceridemia (HP:0002155)1.31321142
118Skin rash (HP:0000988)1.30835373
119Tinnitus (HP:0000360)1.30580019
120Chromosomal breakage induced by crosslinking agents (HP:0003221)1.30368262
121Decreased activity of mitochondrial respiratory chain (HP:0008972)1.30315337
122Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.30315337
123Renal tubular dysfunction (HP:0000124)1.30130891
124Abnormality of nail color (HP:0100643)1.29442917
125Abnormality of dental color (HP:0011073)1.29293674
126Seborrheic dermatitis (HP:0001051)1.27633884
127High pitched voice (HP:0001620)1.26680088
128Granulocytopenia (HP:0001913)1.25103243
129Gastrointestinal dysmotility (HP:0002579)1.24935370
130Short 5th finger (HP:0009237)1.24500418
131Patellar aplasia (HP:0006443)1.24275705
132Prominent nose (HP:0000448)1.24045485
133Palpitations (HP:0001962)1.23135050
134Oral leukoplakia (HP:0002745)1.22549815
135Increased mean platelet volume (HP:0011877)1.22375803
136Abnormal platelet volume (HP:0011876)1.22232630
137Sandal gap (HP:0001852)1.22025088
138Abnormality of sulfur amino acid metabolism (HP:0004339)1.21965358
139Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.21818477
140Thin skin (HP:0000963)1.20190107
141Childhood onset (HP:0011463)1.18724164
142Increased serum lactate (HP:0002151)1.18114862
143Anxiety (HP:0000739)1.17349035

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK17.77355648
2CDC74.13672656
3TLK13.57839598
4RIPK43.36112593
5NME23.27273422
6PRPF4B2.90108313
7BRSK12.78816525
8STK42.67701325
9BUB12.49632297
10VRK12.28825971
11WEE12.27556331
12SCYL22.24078663
13NEK22.19786286
14DYRK32.17187985
15RAF12.10665228
16EEF2K1.99904465
17TAOK21.99238017
18KSR21.98496055
19BMX1.84167983
20STK101.83421766
21ZAK1.81396871
22BRSK21.80419516
23CDK121.78101358
24PIM11.53625841
25AURKB1.51016605
26MAPK111.41799262
27NEK11.40561235
28AURKA1.40206195
29TTK1.34923280
30MAP3K101.30136083
31MAP3K81.29542524
32KSR11.24851792
33PLK11.24263440
34CDK41.23762976
35MAP3K111.20910138
36MAPKAPK31.20511132
37RPS6KB21.20000712
38CHEK21.19862251
39MAPKAPK51.19198904
40RPS6KA51.08208737
41BMPR21.07591252
42ATR1.07174737
43BRAF1.04447149
44MAP3K21.04365826
45TRPM71.04223103
46GRK61.04014329
47STK161.02827315
48SYK1.00194971
49MARK30.99189315
50TEC0.99123249
51PBK0.98775442
52TAOK30.95727217
53NUAK10.95552549
54CHEK10.94637499
55BTK0.90451270
56JAK20.88395021
57CDK60.87901523
58NTRK30.86716224
59ATM0.84435078
60WNK10.84161356
61JAK30.83436146
62CDK70.81803157
63MAP2K30.81598442
64PIM20.78494116
65SRPK10.76917864
66ABL20.76734005
67MST40.76232385
68MATK0.74893228
69MAP3K10.72912632
70TGFBR20.72204265
71FLT30.71706205
72MELK0.71310310
73MAP4K10.69852305
74BRD40.69732895
75PDK20.69385497
76CLK10.69362284
77PKN20.69081831
78ERBB20.67013814
79MAP3K60.65441906
80TAOK10.65245331
81LRRK20.64494696
82KDR0.61734433
83GRK50.61704044
84LYN0.61693343
85ACVR1B0.61378130
86MAP2K20.59064739
87TRIB30.57805641
88CDK20.56329002
89MAP3K50.55979438
90EIF2AK20.53120172
91EIF2AK30.52981697
92PLK30.51691784
93CDK10.49285983
94ICK0.48708525
95CSNK2A10.47363154
96HIPK20.47213489
97MAPKAPK20.46228578
98MKNK10.46188602
99MAPK30.46049816
100SMG10.43972377
101NME10.43127168
102CDK190.42763054
103RET0.42476928
104PRKAA10.42354747
105CDK90.42257311
106RPS6KL10.41358026
107RPS6KC10.41358026
108CSNK2A20.40611964
109PLK40.39222828
110CDC42BPA0.39052741
111CCNB10.39000135
112ERN10.38961622
113TYK20.38938104
114CSNK1D0.38517942
115SGK10.38234695
116CDK11A0.36588020
117PRKDC0.36528339
118AKT30.35672346
119TSSK60.35521300
120GRK70.35291856
121DYRK1B0.35067207
122PRKAA20.34748336
123PTK2B0.34709950
124STK30.34247024
125CDK150.33934663
126MTOR0.33689455
127ALK0.33135507
128TNK20.32644197
129RPS6KA40.31597031
130MAP2K10.28877057
131DAPK20.27791105
132CDK180.27702489
133PRKACG0.26619129
134DAPK10.24682087
135IKBKB0.23369608
136AKT10.23060646
137AKT20.21937828
138PAK10.21918916
139TBK10.21800497
140MAPK140.21435923
141MAPK120.21287816

Predicted pathways (KEGG)

RankGene SetZ-score
1Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008608.18975857
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005245.32147731
3Vitamin B6 metabolism_Homo sapiens_hsa007504.69964123
4DNA replication_Homo sapiens_hsa030304.69718492
5Systemic lupus erythematosus_Homo sapiens_hsa053224.20556326
6Ribosome_Homo sapiens_hsa030102.84339865
7Mismatch repair_Homo sapiens_hsa034302.79026275
8Cell cycle_Homo sapiens_hsa041102.74586380
9One carbon pool by folate_Homo sapiens_hsa006702.21715316
10Alcoholism_Homo sapiens_hsa050342.15567553
11Nucleotide excision repair_Homo sapiens_hsa034202.09780108
12Base excision repair_Homo sapiens_hsa034102.06107015
13Homologous recombination_Homo sapiens_hsa034401.98524432
14Sulfur relay system_Homo sapiens_hsa041221.94941483
15Spliceosome_Homo sapiens_hsa030401.87543584
16Pyrimidine metabolism_Homo sapiens_hsa002401.73472280
17Proteasome_Homo sapiens_hsa030501.69121477
18RNA transport_Homo sapiens_hsa030131.59244174
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.57172502
20Fanconi anemia pathway_Homo sapiens_hsa034601.55987309
21Hematopoietic cell lineage_Homo sapiens_hsa046401.40267432
22ABC transporters_Homo sapiens_hsa020101.39314986
23Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.36748991
24p53 signaling pathway_Homo sapiens_hsa041151.36257005
25Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.32641800
26Viral carcinogenesis_Homo sapiens_hsa052031.26655272
27RNA polymerase_Homo sapiens_hsa030201.26222532
28Selenocompound metabolism_Homo sapiens_hsa004501.23725589
29African trypanosomiasis_Homo sapiens_hsa051431.21242701
30Non-homologous end-joining_Homo sapiens_hsa034501.18234864
31Fructose and mannose metabolism_Homo sapiens_hsa000511.03213882
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.97556930
33Steroid biosynthesis_Homo sapiens_hsa001000.95877330
34Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.94662534
35Bladder cancer_Homo sapiens_hsa052190.93742530
36Fatty acid elongation_Homo sapiens_hsa000620.93318402
37Cysteine and methionine metabolism_Homo sapiens_hsa002700.93273349
38Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.92827252
39RNA degradation_Homo sapiens_hsa030180.92500593
40Parkinsons disease_Homo sapiens_hsa050120.91694428
41Malaria_Homo sapiens_hsa051440.90878346
42Glutathione metabolism_Homo sapiens_hsa004800.90385760
43Herpes simplex infection_Homo sapiens_hsa051680.89582057
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.86824708
45Type II diabetes mellitus_Homo sapiens_hsa049300.84715949
46Folate biosynthesis_Homo sapiens_hsa007900.81291875
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.80812668
48Fatty acid metabolism_Homo sapiens_hsa012120.80621507
49Purine metabolism_Homo sapiens_hsa002300.79666936
50mRNA surveillance pathway_Homo sapiens_hsa030150.76676444
51Pentose phosphate pathway_Homo sapiens_hsa000300.74067753
52HIF-1 signaling pathway_Homo sapiens_hsa040660.73385271
53Central carbon metabolism in cancer_Homo sapiens_hsa052300.70035845
54Basal transcription factors_Homo sapiens_hsa030220.69942014
55Oocyte meiosis_Homo sapiens_hsa041140.69435553
56Other glycan degradation_Homo sapiens_hsa005110.69133923
57Olfactory transduction_Homo sapiens_hsa047400.66832134
58Apoptosis_Homo sapiens_hsa042100.65030258
59Non-small cell lung cancer_Homo sapiens_hsa052230.64458227
60Collecting duct acid secretion_Homo sapiens_hsa049660.63519745
61mTOR signaling pathway_Homo sapiens_hsa041500.63085254
62Pyruvate metabolism_Homo sapiens_hsa006200.62127118
63Small cell lung cancer_Homo sapiens_hsa052220.62001976
64Chronic myeloid leukemia_Homo sapiens_hsa052200.61782924
65Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.61329961
66Huntingtons disease_Homo sapiens_hsa050160.61220015
67Glycerophospholipid metabolism_Homo sapiens_hsa005640.58941679
68Caffeine metabolism_Homo sapiens_hsa002320.57003353
69Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.56240601
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.55724534
71Biosynthesis of amino acids_Homo sapiens_hsa012300.55583203
72Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.55068889
73Carbohydrate digestion and absorption_Homo sapiens_hsa049730.54588103
74Butanoate metabolism_Homo sapiens_hsa006500.53405456
75Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.51998786
76Propanoate metabolism_Homo sapiens_hsa006400.49537851
77Jak-STAT signaling pathway_Homo sapiens_hsa046300.48513034
78B cell receptor signaling pathway_Homo sapiens_hsa046620.47510725
79Carbon metabolism_Homo sapiens_hsa012000.47109454
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.46841341
81Epstein-Barr virus infection_Homo sapiens_hsa051690.45899934
82Oxidative phosphorylation_Homo sapiens_hsa001900.44779013
83Renal cell carcinoma_Homo sapiens_hsa052110.44691151
84Hepatitis B_Homo sapiens_hsa051610.42648464
85Drug metabolism - other enzymes_Homo sapiens_hsa009830.41284063
86Thyroid cancer_Homo sapiens_hsa052160.39593092
87Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.39451901
88Metabolic pathways_Homo sapiens_hsa011000.39365396
89Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.38462278
90Insulin signaling pathway_Homo sapiens_hsa049100.37433356
91Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.36532994
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36202257
93SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34461420
94Measles_Homo sapiens_hsa051620.33444505
95Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.32059807
96HTLV-I infection_Homo sapiens_hsa051660.31846122
97Antigen processing and presentation_Homo sapiens_hsa046120.31346191
98Prolactin signaling pathway_Homo sapiens_hsa049170.30853100
99Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.29090022
100VEGF signaling pathway_Homo sapiens_hsa043700.27857797
101Asthma_Homo sapiens_hsa053100.26853106
102Pancreatic cancer_Homo sapiens_hsa052120.25020553
103Alzheimers disease_Homo sapiens_hsa050100.22592733
104Cyanoamino acid metabolism_Homo sapiens_hsa004600.22103999
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21413008
1062-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.18667861
107AMPK signaling pathway_Homo sapiens_hsa041520.18610074
108Complement and coagulation cascades_Homo sapiens_hsa046100.15564613
109Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.15273532
110MicroRNAs in cancer_Homo sapiens_hsa052060.14536171
111Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.14276943
112Protein export_Homo sapiens_hsa030600.13643513
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.12718940
114Influenza A_Homo sapiens_hsa051640.11579472
115Lysine degradation_Homo sapiens_hsa003100.11541907
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.11123265
117beta-Alanine metabolism_Homo sapiens_hsa004100.10027009
118Platelet activation_Homo sapiens_hsa046110.08154132
119Prostate cancer_Homo sapiens_hsa052150.07328530
120Nitrogen metabolism_Homo sapiens_hsa009100.05537119
121FoxO signaling pathway_Homo sapiens_hsa040680.03873190
122Glioma_Homo sapiens_hsa052140.03531349
123Acute myeloid leukemia_Homo sapiens_hsa052210.03268803
124Fatty acid degradation_Homo sapiens_hsa000710.02967804
125Maturity onset diabetes of the young_Homo sapiens_hsa049500.02222058
126N-Glycan biosynthesis_Homo sapiens_hsa005100.01741313
127Fat digestion and absorption_Homo sapiens_hsa049750.01470743

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