KHDRBS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.18204408
2presynaptic membrane assembly (GO:0097105)4.88505108
3startle response (GO:0001964)4.84804387
4nucleobase catabolic process (GO:0046113)4.83000987
5presynaptic membrane organization (GO:0097090)4.41736099
6ionotropic glutamate receptor signaling pathway (GO:0035235)4.16563251
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.15114494
8righting reflex (GO:0060013)4.12109889
9vocalization behavior (GO:0071625)4.11798972
10postsynaptic membrane organization (GO:0001941)4.11025536
11glutamate receptor signaling pathway (GO:0007215)4.04858162
12regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.75559816
13G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.65690595
14positive regulation of synapse assembly (GO:0051965)3.62710922
15neuron recognition (GO:0008038)3.61866969
16gamma-aminobutyric acid transport (GO:0015812)3.58725135
17behavioral response to nicotine (GO:0035095)3.50881883
18establishment of mitochondrion localization (GO:0051654)3.49783052
19protein localization to synapse (GO:0035418)3.49034097
20regulation of glutamate receptor signaling pathway (GO:1900449)3.43454353
21synaptic transmission, glutamatergic (GO:0035249)3.42078178
22negative regulation of synaptic transmission, GABAergic (GO:0032229)3.36139234
23opioid receptor signaling pathway (GO:0038003)3.35148496
24neurotransmitter-gated ion channel clustering (GO:0072578)3.34815147
25neuron-neuron synaptic transmission (GO:0007270)3.32491888
26central nervous system projection neuron axonogenesis (GO:0021952)3.30845692
27regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.30284438
28protein polyglutamylation (GO:0018095)3.29768886
29cerebral cortex radially oriented cell migration (GO:0021799)3.29041998
30regulation of synapse assembly (GO:0051963)3.27415092
31serotonin receptor signaling pathway (GO:0007210)3.21228002
32forebrain neuron differentiation (GO:0021879)3.19018427
33gamma-aminobutyric acid signaling pathway (GO:0007214)3.18948748
34protein localization to cilium (GO:0061512)3.18596632
35hindbrain development (GO:0030902)3.17724183
36negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.17449185
37axonal fasciculation (GO:0007413)3.15305842
38glycosphingolipid biosynthetic process (GO:0006688)3.14191542
39positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.13230236
40DNA double-strand break processing (GO:0000729)3.11116250
41somite development (GO:0061053)3.08308823
42regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.05445590
43regulation of respiratory system process (GO:0044065)3.03478449
44epithelial cilium movement (GO:0003351)3.02985432
45inner ear receptor stereocilium organization (GO:0060122)2.96806629
46positive regulation of action potential (GO:0045760)2.94177740
47retinal ganglion cell axon guidance (GO:0031290)2.94120134
48regulation of respiratory gaseous exchange (GO:0043576)2.90546965
49regulation of synaptic transmission, glutamatergic (GO:0051966)2.88727861
50positive regulation of protein homodimerization activity (GO:0090073)2.88617327
51spinal cord association neuron differentiation (GO:0021527)2.87936379
52superoxide anion generation (GO:0042554)2.87569806
53response to histamine (GO:0034776)2.87050012
54sequestering of actin monomers (GO:0042989)2.85941953
55heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.83917888
56intraciliary transport (GO:0042073)2.83603060
57positive regulation of synaptic transmission, GABAergic (GO:0032230)2.83583000
58regulation of collateral sprouting (GO:0048670)2.83305799
59neural tube formation (GO:0001841)2.82981011
60regulation of glutamate secretion (GO:0014048)2.82266428
61transmission of nerve impulse (GO:0019226)2.81149844
62negative regulation of dendrite development (GO:2000171)2.81141146
63positive regulation of oligodendrocyte differentiation (GO:0048714)2.80634914
64neuronal action potential (GO:0019228)2.78219746
65reflex (GO:0060004)2.78208061
66nonmotile primary cilium assembly (GO:0035058)2.77521729
67regulation of short-term neuronal synaptic plasticity (GO:0048172)2.77046637
68negative regulation of translation, ncRNA-mediated (GO:0040033)2.75356341
69regulation of translation, ncRNA-mediated (GO:0045974)2.75356341
70negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.75356341
71regulation of cilium movement (GO:0003352)2.75321642
72water-soluble vitamin biosynthetic process (GO:0042364)2.73597661
73adult walking behavior (GO:0007628)2.72763028
74regulation of timing of cell differentiation (GO:0048505)2.72759219
75photoreceptor cell maintenance (GO:0045494)2.70699093
76calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.70531106
77sialylation (GO:0097503)2.70095765
78cilium morphogenesis (GO:0060271)2.69723714
79central nervous system neuron axonogenesis (GO:0021955)2.69347170
80drinking behavior (GO:0042756)2.67735132
81positive regulation of mitochondrial fission (GO:0090141)2.67500685
82limb bud formation (GO:0060174)2.65713317
83cullin deneddylation (GO:0010388)2.65611685
84synaptic vesicle maturation (GO:0016188)2.62787905
85positive regulation of uterine smooth muscle contraction (GO:0070474)2.62320334
86G-protein coupled receptor internalization (GO:0002031)2.61849154
87dendrite development (GO:0016358)2.61842211
88auditory receptor cell stereocilium organization (GO:0060088)2.61680468
89cardiac ventricle formation (GO:0003211)2.61405840
90synapse assembly (GO:0007416)2.61110911
91epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.60462360
92cranial nerve structural organization (GO:0021604)2.58540860
93otic vesicle formation (GO:0030916)2.57783216
94olfactory bulb development (GO:0021772)2.57688726
95hippocampus development (GO:0021766)2.56892670
96regulation of feeding behavior (GO:0060259)2.56672032
97regulation of excitatory postsynaptic membrane potential (GO:0060079)2.56513267
98regulation of synaptic transmission, GABAergic (GO:0032228)2.56463460
99regulation of synapse structural plasticity (GO:0051823)2.56271407
100cranial nerve morphogenesis (GO:0021602)2.55878376
101negative regulation of transcription regulatory region DNA binding (GO:2000678)2.55848545
102positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.55562065
103mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.55562065
104positive regulation of neurotransmitter secretion (GO:0001956)2.55113413
105establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.54838416
106mitochondrion transport along microtubule (GO:0047497)2.54838416
107cell migration in hindbrain (GO:0021535)2.54413716
108regulation of postsynaptic membrane potential (GO:0060078)2.53764537
109negative regulation of astrocyte differentiation (GO:0048712)2.51873598
110facial nerve structural organization (GO:0021612)2.51288294
111long-term synaptic potentiation (GO:0060291)2.49958912
112mechanosensory behavior (GO:0007638)2.49145929
113dendritic spine morphogenesis (GO:0060997)2.48647274
114extracellular negative regulation of signal transduction (GO:1900116)2.48428186
115extracellular regulation of signal transduction (GO:1900115)2.48428186
116cilium assembly (GO:0042384)2.48180256
117pyrimidine nucleobase catabolic process (GO:0006208)2.47416087
118regulation of synapse organization (GO:0050807)2.47375984
119cilium organization (GO:0044782)2.46847113
120ganglion development (GO:0061548)2.46524152
121response to auditory stimulus (GO:0010996)2.46472666
122regulation of synapse maturation (GO:0090128)2.46421057
123cardiac chamber formation (GO:0003207)2.46266761
124spinal cord development (GO:0021510)2.45979201
125membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.45658274
126dentate gyrus development (GO:0021542)2.44505280
127learning (GO:0007612)2.43584349
128regulation of Rac GTPase activity (GO:0032314)2.43244723
129detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.42955463
130cAMP-mediated signaling (GO:0019933)2.42460052
131developmental pigmentation (GO:0048066)2.42263865
132regulation of development, heterochronic (GO:0040034)2.42237515
133auditory behavior (GO:0031223)2.41214982
134mesenchymal cell differentiation involved in renal system development (GO:2001012)2.40729801
135mesenchymal cell differentiation involved in kidney development (GO:0072161)2.40729801
136kidney morphogenesis (GO:0060993)2.40393279
137negative regulation of dendrite morphogenesis (GO:0050774)2.40238694
138L-fucose metabolic process (GO:0042354)2.38553943
139cell differentiation involved in kidney development (GO:0061005)2.38524864
140long-term memory (GO:0007616)2.38393124
141cAMP catabolic process (GO:0006198)2.38139776
142adult behavior (GO:0030534)2.37847680
143retina layer formation (GO:0010842)2.37682663
144response to pheromone (GO:0019236)2.35250062
145membrane hyperpolarization (GO:0060081)2.32191821
146behavioral fear response (GO:0001662)2.31413433
147behavioral defense response (GO:0002209)2.31413433
148neuron remodeling (GO:0016322)2.30916569
149regulation of pigment cell differentiation (GO:0050932)2.30698671
150behavioral response to ethanol (GO:0048149)2.30386921
151urinary tract smooth muscle contraction (GO:0014848)2.29719729
152forebrain neuron development (GO:0021884)2.29346666

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.95238373
2GBX2_23144817_ChIP-Seq_PC3_Human4.44307524
3ZNF274_21170338_ChIP-Seq_K562_Hela2.93293207
4* ZFP57_27257070_Chip-Seq_ESCs_Mouse2.85126360
5TAF15_26573619_Chip-Seq_HEK293_Human2.72119817
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.68398459
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.55539625
8TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.51935313
9SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.50125198
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.46214712
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.42783938
12BMI1_23680149_ChIP-Seq_NPCS_Mouse2.42054045
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.38324385
14CBX2_27304074_Chip-Seq_ESCs_Mouse2.37261417
15SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.32091236
16* IGF1R_20145208_ChIP-Seq_DFB_Human2.32074269
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26977878
18* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.23246151
19* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.22420589
20SALL1_21062744_ChIP-ChIP_HESCs_Human2.14073992
21CTBP2_25329375_ChIP-Seq_LNCAP_Human2.11168749
22* P300_19829295_ChIP-Seq_ESCs_Human2.03577025
23JARID2_20075857_ChIP-Seq_MESCs_Mouse2.03399138
24RNF2_18974828_ChIP-Seq_MESCs_Mouse1.99763935
25EZH2_18974828_ChIP-Seq_MESCs_Mouse1.99763935
26PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.99011632
27SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.97493859
28* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.91960868
29CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.88715660
30RNF2_27304074_Chip-Seq_NSC_Mouse1.88530160
31* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.88527911
32FUS_26573619_Chip-Seq_HEK293_Human1.87732703
33VDR_22108803_ChIP-Seq_LS180_Human1.82340756
34* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.78822736
35PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.78557453
36RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.74337360
37* EZH2_27294783_Chip-Seq_ESCs_Mouse1.74003482
38MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.72784357
39RNF2_27304074_Chip-Seq_ESCs_Mouse1.72319309
40* FLI1_27457419_Chip-Seq_LIVER_Mouse1.72252276
41* SMAD4_21799915_ChIP-Seq_A2780_Human1.69231625
42* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.67612600
43* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.65302181
44* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.64677523
45* NANOG_18555785_Chip-Seq_ESCs_Mouse1.63819574
46REST_21632747_ChIP-Seq_MESCs_Mouse1.63804911
47* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.62280519
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.61227959
49HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.60556969
50* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.58990615
51* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.58379592
52CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57126042
53* SMAD3_21741376_ChIP-Seq_EPCs_Human1.56400541
54PCGF2_27294783_Chip-Seq_NPCs_Mouse1.55744713
55EWS_26573619_Chip-Seq_HEK293_Human1.54903601
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.54490954
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.52910789
58POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.52519190
59TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.52519190
60CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.50204763
61* E2F1_18555785_Chip-Seq_ESCs_Mouse1.50033421
62* P53_22387025_ChIP-Seq_ESCs_Mouse1.48014836
63* NFE2_27457419_Chip-Seq_LIVER_Mouse1.47564167
64HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.45911625
65* ER_23166858_ChIP-Seq_MCF-7_Human1.44001580
66IRF1_19129219_ChIP-ChIP_H3396_Human1.42967823
67* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.42952747
68MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.42215093
69BP1_19119308_ChIP-ChIP_Hs578T_Human1.38293213
70* CMYC_18555785_Chip-Seq_ESCs_Mouse1.38276797
71NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.38255800
72REST_18959480_ChIP-ChIP_MESCs_Mouse1.35146424
73* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34959646
74AR_25329375_ChIP-Seq_VCAP_Human1.34847894
75* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.34587150
76* EZH2_27294783_Chip-Seq_NPCs_Mouse1.33871278
77POU5F1_16153702_ChIP-ChIP_HESCs_Human1.33474875
78* STAT3_18555785_Chip-Seq_ESCs_Mouse1.33421352
79UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.33239653
80* AR_21572438_ChIP-Seq_LNCaP_Human1.33070780
81ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.32824103
82FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.32487994
83DROSHA_22980978_ChIP-Seq_HELA_Human1.30858824
84IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30636240
85CBP_20019798_ChIP-Seq_JUKART_Human1.30636240
86* P300_18555785_Chip-Seq_ESCs_Mouse1.30582614
87KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.29859239
88SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29101320
89* NMYC_18555785_Chip-Seq_ESCs_Mouse1.29030211
90STAT3_23295773_ChIP-Seq_U87_Human1.25892829
91AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.23995438
92RUNX2_22187159_ChIP-Seq_PCA_Human1.23773251
93NR3C1_21868756_ChIP-Seq_MCF10A_Human1.23481810
94* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23292517
95BCAT_22108803_ChIP-Seq_LS180_Human1.23028265
96BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.22920843
97* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.21022358
98* SOX2_18555785_Chip-Seq_ESCs_Mouse1.20895209
99TCF4_23295773_ChIP-Seq_U87_Human1.20802543
100CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19287553
101CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.18852712
102KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17967847
103TAL1_26923725_Chip-Seq_HPCs_Mouse1.17581085
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.17112789
105* KDM2B_26808549_Chip-Seq_REH_Human1.16647815
106TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16551541
107* SOX2_21211035_ChIP-Seq_LN229_Gbm1.15391045
108TP53_18474530_ChIP-ChIP_U2OS_Human1.14346620
109IKZF1_21737484_ChIP-ChIP_HCT116_Human1.14242879
110* OCT4_18555785_Chip-Seq_ESCs_Mouse1.13933822
111GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.13621114
112TP53_22573176_ChIP-Seq_HFKS_Human1.12983861
113E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.12561432
114MYC_18940864_ChIP-ChIP_HL60_Human1.12546623
115PRDM14_20953172_ChIP-Seq_ESCs_Human1.12225336
116SOX9_26525672_Chip-Seq_HEART_Mouse1.11749774
117* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11632872
118RBPJ_22232070_ChIP-Seq_NCS_Mouse1.10462061
119* PU1_27457419_Chip-Seq_LIVER_Mouse1.10280814
120* JUN_21703547_ChIP-Seq_K562_Human1.09830215
121* ZFX_18555785_Chip-Seq_ESCs_Mouse1.09206704
122* KLF4_18555785_Chip-Seq_ESCs_Mouse1.08511770
123TCF4_22108803_ChIP-Seq_LS180_Human1.04725615
124EST1_17652178_ChIP-ChIP_JURKAT_Human1.04296876
125NANOG_19829295_ChIP-Seq_ESCs_Human1.01904129
126SOX2_19829295_ChIP-Seq_ESCs_Human1.01904129
127SOX2_16153702_ChIP-ChIP_HESCs_Human0.99759786
128FLI1_21867929_ChIP-Seq_TH2_Mouse0.99460868
129EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.98745447
130GABP_17652178_ChIP-ChIP_JURKAT_Human0.98389048
131STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.96803038

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.62179497
2MP0001188_hyperpigmentation3.55864871
3MP0005645_abnormal_hypothalamus_physiol2.98231732
4MP0006276_abnormal_autonomic_nervous2.86769612
5MP0006292_abnormal_olfactory_placode2.75505045
6MP0005646_abnormal_pituitary_gland2.60545444
7MP0002735_abnormal_chemical_nociception2.51457590
8MP0004859_abnormal_synaptic_plasticity2.50625057
9MP0005423_abnormal_somatic_nervous2.49169550
10MP0009745_abnormal_behavioral_response2.44938355
11MP0001968_abnormal_touch/_nociception2.43601942
12MP0003635_abnormal_synaptic_transmissio2.39985131
13MP0001529_abnormal_vocalization2.37864111
14MP0001486_abnormal_startle_reflex2.35948320
15MP0002736_abnormal_nociception_after2.33231505
16MP0002102_abnormal_ear_morphology2.30532040
17MP0002572_abnormal_emotion/affect_behav2.23338500
18MP0002063_abnormal_learning/memory/cond2.21861324
19MP0004742_abnormal_vestibular_system2.14341330
20MP0000778_abnormal_nervous_system2.13644109
21MP0003787_abnormal_imprinting2.13178601
22MP0008877_abnormal_DNA_methylation1.96415696
23MP0005171_absent_coat_pigmentation1.92900254
24MP0002064_seizures1.87560059
25MP0002184_abnormal_innervation1.86964945
26MP0002734_abnormal_mechanical_nocicepti1.86076561
27MP0005409_darkened_coat_color1.85411222
28MP0001984_abnormal_olfaction1.84968729
29MP0002067_abnormal_sensory_capabilities1.82964373
30MP0000566_synostosis1.77024060
31MP0002272_abnormal_nervous_system1.73923406
32MP0004270_analgesia1.73479245
33MP0002557_abnormal_social/conspecific_i1.72978459
34MP0009046_muscle_twitch1.70503495
35MP0001440_abnormal_grooming_behavior1.68401630
36MP0003011_delayed_dark_adaptation1.68356971
37MP0004133_heterotaxia1.67749618
38MP0001501_abnormal_sleep_pattern1.65415691
39MP0002638_abnormal_pupillary_reflex1.61452656
40MP0005187_abnormal_penis_morphology1.59045116
41MP0003136_yellow_coat_color1.58833699
42MP0010386_abnormal_urinary_bladder1.58728768
43MP0003122_maternal_imprinting1.56909844
44MP0001502_abnormal_circadian_rhythm1.56755413
45MP0002234_abnormal_pharynx_morphology1.56533612
46MP0000015_abnormal_ear_pigmentation1.54968008
47MP0004142_abnormal_muscle_tone1.51697334
48MP0000631_abnormal_neuroendocrine_gland1.49705461
49MP0000569_abnormal_digit_pigmentation1.49478242
50MP0003119_abnormal_digestive_system1.47330481
51MP0002876_abnormal_thyroid_physiology1.46698159
52MP0002277_abnormal_respiratory_mucosa1.46072822
53MP0000026_abnormal_inner_ear1.45821029
54MP0005386_behavior/neurological_phenoty1.41685496
55MP0004924_abnormal_behavior1.41685496
56MP0001905_abnormal_dopamine_level1.41521813
57MP0001293_anophthalmia1.40133184
58MP0001970_abnormal_pain_threshold1.34361687
59MP0001986_abnormal_taste_sensitivity1.28459441
60MP0003938_abnormal_ear_development1.27263026
61MP0005551_abnormal_eye_electrophysiolog1.27120407
62MP0002733_abnormal_thermal_nociception1.26885505
63MP0009379_abnormal_foot_pigmentation1.26419855
64MP0001963_abnormal_hearing_physiology1.24224756
65MP0002163_abnormal_gland_morphology1.19856417
66MP0003121_genomic_imprinting1.15620357
67MP0005084_abnormal_gallbladder_morpholo1.12159601
68MP0002938_white_spotting1.08413853
69MP0002882_abnormal_neuron_morphology1.07187257
70MP0005379_endocrine/exocrine_gland_phen1.06988157
71MP0003941_abnormal_skin_development1.06661297
72MP0003567_abnormal_fetal_cardiomyocyte1.06388457
73MP0002233_abnormal_nose_morphology1.04280425
74MP0002752_abnormal_somatic_nervous1.03316862
75MP0000647_abnormal_sebaceous_gland1.02927068
76MP0002751_abnormal_autonomic_nervous1.02849316
77MP0008058_abnormal_DNA_repair1.00541433
78MP0004885_abnormal_endolymph1.00378915
79MP0001346_abnormal_lacrimal_gland0.98714192
80MP0000049_abnormal_middle_ear0.98708497
81MP0005391_vision/eye_phenotype0.98336070
82MP0005253_abnormal_eye_physiology0.98140329
83MP0006072_abnormal_retinal_apoptosis0.95939393
84MP0005499_abnormal_olfactory_system0.95312417
85MP0005394_taste/olfaction_phenotype0.95312417
86MP0004043_abnormal_pH_regulation0.94634178
87MP0003890_abnormal_embryonic-extraembry0.91985687
88MP0005248_abnormal_Harderian_gland0.91140248
89MP0000681_abnormal_thyroid_gland0.90798778
90MP0005174_abnormal_tail_pigmentation0.90553476
91MP0001764_abnormal_homeostasis0.89690697
92MP0008789_abnormal_olfactory_epithelium0.89471377
93MP0003879_abnormal_hair_cell0.89077273
94MP0002066_abnormal_motor_capabilities/c0.87388730
95MP0000955_abnormal_spinal_cord0.86797482
96MP0004145_abnormal_muscle_electrophysio0.84948406
97MP0003937_abnormal_limbs/digits/tail_de0.84859446
98MP0002653_abnormal_ependyma_morphology0.83581553
99MP0002152_abnormal_brain_morphology0.82868668
100MP0002177_abnormal_outer_ear0.81364018
101MP0004811_abnormal_neuron_physiology0.81154366
102MP0002928_abnormal_bile_duct0.79579514
103MP0003315_abnormal_perineum_morphology0.78246044
104MP0008872_abnormal_physiological_respon0.77676016
105MP0001286_abnormal_eye_development0.76607956
106MP0009250_abnormal_appendicular_skeleto0.76109704
107MP0002229_neurodegeneration0.75962130
108MP0000372_irregular_coat_pigmentation0.74298399
109MP0002095_abnormal_skin_pigmentation0.73182747
110MP0008569_lethality_at_weaning0.72156329
111MP0002822_catalepsy0.72041195
112MP0002009_preneoplasia0.68251696
113MP0003385_abnormal_body_wall0.67353765
114MP0003137_abnormal_impulse_conducting0.67033854
115MP0004381_abnormal_hair_follicle0.66236407
116MP0002249_abnormal_larynx_morphology0.65337889
117MP0005257_abnormal_intraocular_pressure0.63936646
118MP0002069_abnormal_eating/drinking_beha0.63046915
119MP0001177_atelectasis0.62287044
120MP0001485_abnormal_pinna_reflex0.62075490
121MP0008995_early_reproductive_senescence0.60792064
122MP0000538_abnormal_urinary_bladder0.59614114
123MP0003861_abnormal_nervous_system0.58994010
124MP0005195_abnormal_posterior_eye0.57755367
125MP0009697_abnormal_copulation0.57261033

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.30771778
2Febrile seizures (HP:0002373)4.78492358
3Protruding tongue (HP:0010808)3.59524994
4Hyperventilation (HP:0002883)3.57144247
5Epileptic encephalopathy (HP:0200134)3.22276850
6Atonic seizures (HP:0010819)3.00270766
7Chromosomal breakage induced by crosslinking agents (HP:0003221)2.99566214
8Focal seizures (HP:0007359)2.99097351
9Myokymia (HP:0002411)2.95604773
10Abnormal hair whorl (HP:0010721)2.94124545
11Septo-optic dysplasia (HP:0100842)2.93224001
12Colon cancer (HP:0003003)2.92041201
13Fair hair (HP:0002286)2.91155407
14Medial flaring of the eyebrow (HP:0010747)2.89530690
15Hyperglycinemia (HP:0002154)2.83879401
16Amyotrophic lateral sclerosis (HP:0007354)2.82463542
17Absent speech (HP:0001344)2.78568400
18Broad-based gait (HP:0002136)2.75723864
19Hypothermia (HP:0002045)2.70014700
20Gait imbalance (HP:0002141)2.68770406
21Nephrogenic diabetes insipidus (HP:0009806)2.57632936
22Generalized hypopigmentation of hair (HP:0011358)2.56363483
23Prostate neoplasm (HP:0100787)2.53893437
24Methylmalonic acidemia (HP:0002912)2.53534560
25Congenital sensorineural hearing impairment (HP:0008527)2.52138630
26Limb dystonia (HP:0002451)2.47934478
27Chromsome breakage (HP:0040012)2.47866478
28Congenital primary aphakia (HP:0007707)2.45695902
29Absence seizures (HP:0002121)2.43273165
30Abnormality of the corticospinal tract (HP:0002492)2.39239699
31Thyroid-stimulating hormone excess (HP:0002925)2.37338024
32Optic nerve hypoplasia (HP:0000609)2.36690841
33Lissencephaly (HP:0001339)2.36566609
34Atrophy/Degeneration involving motor neurons (HP:0007373)2.30255339
35Blue irides (HP:0000635)2.29428396
36Abnormality of the labia minora (HP:0012880)2.28720825
37Excessive salivation (HP:0003781)2.27621903
38Drooling (HP:0002307)2.27621903
39Abnormality of the renal medulla (HP:0100957)2.27549336
40Stomach cancer (HP:0012126)2.25264584
41Dialeptic seizures (HP:0011146)2.24860163
42Postaxial hand polydactyly (HP:0001162)2.22445836
43Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.21824247
44Degeneration of the lateral corticospinal tracts (HP:0002314)2.21824247
45Hemiparesis (HP:0001269)2.19865069
46Abnormality of incisor morphology (HP:0011063)2.19659507
47Absent/shortened dynein arms (HP:0200106)2.19392946
48Dynein arm defect of respiratory motile cilia (HP:0012255)2.19392946
49Congenital stationary night blindness (HP:0007642)2.19391778
50Broad foot (HP:0001769)2.19077576
51Anencephaly (HP:0002323)2.17663372
52True hermaphroditism (HP:0010459)2.17589498
53Growth hormone deficiency (HP:0000824)2.16829387
54Exotropia (HP:0000577)2.13365196
55White forelock (HP:0002211)2.12632524
56Narrow nasal bridge (HP:0000446)2.12540495
57Abnormal ciliary motility (HP:0012262)2.11519547
58Tubulointerstitial nephritis (HP:0001970)2.11112770
59Intestinal atresia (HP:0011100)2.10919699
60Generalized tonic-clonic seizures (HP:0002069)2.08837356
61Aplasia/Hypoplasia of the lens (HP:0008063)2.08692027
62Chronic hepatic failure (HP:0100626)2.08656125
63Volvulus (HP:0002580)2.06810699
64Progressive cerebellar ataxia (HP:0002073)2.06571726
65Sclerocornea (HP:0000647)2.06236058
66Polyphagia (HP:0002591)2.05857244
67Fetal akinesia sequence (HP:0001989)2.04834216
68Abolished electroretinogram (ERG) (HP:0000550)2.04307357
69Aplasia/Hypoplasia of the tongue (HP:0010295)2.02486031
70Inability to walk (HP:0002540)2.01742159
71Postaxial foot polydactyly (HP:0001830)2.00203355
72Midline defect of the nose (HP:0004122)1.99326164
73Aplasia cutis congenita (HP:0001057)1.99211182
74Preaxial hand polydactyly (HP:0001177)1.98272418
75Absent septum pellucidum (HP:0001331)1.98092014
76Acute necrotizing encephalopathy (HP:0006965)1.97431142
77Cystic liver disease (HP:0006706)1.96847779
78Genital tract atresia (HP:0001827)1.96010798
79Abnormality of the septum pellucidum (HP:0007375)1.95650337
80Anophthalmia (HP:0000528)1.95553967
81Pachygyria (HP:0001302)1.95273609
82Methylmalonic aciduria (HP:0012120)1.94883134
83Patchy hypopigmentation of hair (HP:0011365)1.94660667
84Abnormality of salivation (HP:0100755)1.94309965
85Severe visual impairment (HP:0001141)1.93736855
86Vaginal atresia (HP:0000148)1.93480209
87Hepatoblastoma (HP:0002884)1.92036225
88Astrocytoma (HP:0009592)1.91816708
89Abnormality of the astrocytes (HP:0100707)1.91816708
90Pancreatic fibrosis (HP:0100732)1.91161731
91Decreased central vision (HP:0007663)1.90990454
92Absent eyebrow (HP:0002223)1.90138243
93Poor coordination (HP:0002370)1.88647923
94Decreased testicular size (HP:0008734)1.85825546
95Abnormality of the lower motor neuron (HP:0002366)1.85753784
96Epileptiform EEG discharges (HP:0011182)1.85733164
97Renal hypoplasia (HP:0000089)1.85690864
98Abnormality of midbrain morphology (HP:0002418)1.85469574
99Molar tooth sign on MRI (HP:0002419)1.85469574
100Gonadotropin excess (HP:0000837)1.84638532
101Hypsarrhythmia (HP:0002521)1.84591667
102Esotropia (HP:0000565)1.84412293
103Tented upper lip vermilion (HP:0010804)1.84118438
104Short tibia (HP:0005736)1.83552676
105Cupped ear (HP:0000378)1.83471369
106Increased IgM level (HP:0003496)1.82862336
107Ependymoma (HP:0002888)1.82579489
108Progressive macrocephaly (HP:0004481)1.81394162
109Morphological abnormality of the pyramidal tract (HP:0002062)1.81066652
110Gastroesophageal reflux (HP:0002020)1.80881770
111Sleep apnea (HP:0010535)1.80760347
112Abnormal respiratory motile cilium morphology (HP:0005938)1.80553329
113Abnormal respiratory epithelium morphology (HP:0012253)1.80553329
1143-Methylglutaconic aciduria (HP:0003535)1.80240754
115Nephronophthisis (HP:0000090)1.79608035
116Abnormality of serine family amino acid metabolism (HP:0010894)1.79358881
117Abnormality of glycine metabolism (HP:0010895)1.79358881
118EEG with generalized epileptiform discharges (HP:0011198)1.78860162
119Aplasia/Hypoplasia of the tibia (HP:0005772)1.78721454
120Pendular nystagmus (HP:0012043)1.78582444
121Optic neuritis (HP:0100653)1.78334878
122Retrobulbar optic neuritis (HP:0100654)1.78334878
123Morphological abnormality of the middle ear (HP:0008609)1.77325248
124Progressive inability to walk (HP:0002505)1.77276046
125Cutaneous finger syndactyly (HP:0010554)1.76331683
126Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.76309858
127Spastic tetraplegia (HP:0002510)1.75107924
128Stenosis of the external auditory canal (HP:0000402)1.74907948
129Genetic anticipation (HP:0003743)1.74629812
130Abnormal eating behavior (HP:0100738)1.74563795
131Aplasia/Hypoplasia of the fovea (HP:0008060)1.74402626
132Hypoplasia of the fovea (HP:0007750)1.74402626
133Short foot (HP:0001773)1.74278286
134Retinal dysplasia (HP:0007973)1.72618179
135Heterochromia iridis (HP:0001100)1.71972547
136Type II lissencephaly (HP:0007260)1.70761552
137Renal cortical cysts (HP:0000803)1.70674798
138Pancreatic cysts (HP:0001737)1.70035954
139Narrow forehead (HP:0000341)1.69706056
140Scrotal hypoplasia (HP:0000046)1.69140478
141Decreased lacrimation (HP:0000633)1.67363543
142Gaze-evoked nystagmus (HP:0000640)1.67185501
143Abnormality of the renal collecting system (HP:0004742)1.66995314
144Specific learning disability (HP:0001328)1.66349489
145Palpebral edema (HP:0100540)1.65672684
146Chorioretinal coloboma (HP:0000567)1.65025464
147Hip dysplasia (HP:0001385)1.64398960
148Abnormality of the nasolacrimal system (HP:0000614)1.64389555
149Male pseudohermaphroditism (HP:0000037)1.64241482
150Parakeratosis (HP:0001036)1.64012963
151Conical tooth (HP:0000698)1.63716602
152Oligodactyly (hands) (HP:0001180)1.63487646

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.42447246
2MAP4K23.73026558
3NTRK32.89529789
4TNIK2.63288100
5EPHA42.60140105
6MAP2K72.59515371
7SIK32.57918552
8MARK12.55674499
9MAPK132.36170816
10MAP3K122.31355329
11PRPF4B2.17370054
12BCKDK2.01060251
13BMPR1B1.96297707
14YES11.92183869
15STK161.91777278
16ADRBK21.82955486
17TRIM281.81259871
18FRK1.80000130
19CSNK1G21.70152198
20BMPR21.61953043
21GRK71.55934638
22CSNK1G31.50796233
23MKNK21.49318414
24SGK21.45519528
25ERBB31.45350127
26CSNK1A1L1.43396486
27NTRK21.41035630
28INSRR1.40707932
29SIK21.38533129
30MAP3K41.37410779
31CSNK1G11.37200497
32EIF2AK21.36077093
33ZAK1.34320399
34CDK31.34163871
35TXK1.32364239
36BCR1.31975797
37AKT31.25721215
38MUSK1.24499122
39PLK21.22772826
40IRAK41.22080593
41RIPK41.21764132
42SRPK11.17681919
43DYRK21.14922432
44PINK11.11930686
45PAK31.06783696
46EPHA31.06401305
47SGK4940.99239912
48SGK2230.99239912
49DYRK30.98486022
50MAP3K140.97653343
51CDK80.95852281
52VRK10.95527248
53MKNK10.94080339
54FGFR20.91424611
55CAMK2A0.89410933
56MINK10.88086167
57FES0.87357500
58PRKCE0.86641475
59WNK40.84335482
60CCNB10.83969268
61TNK20.83668501
62CAMK2B0.82509359
63PNCK0.81425036
64WNK30.79946145
65PAK60.79419308
66TIE10.77893101
67PKN10.75720668
68KSR10.75245016
69BRD40.74027672
70IRAK20.73880045
71DYRK1A0.73239135
72PRKD30.71978523
73GRK10.69970920
74DAPK20.69370330
75PRKCG0.68560196
76SGK10.67953651
77SGK30.66002616
78RPS6KA40.65791218
79EPHB20.64934473
80STK390.63759321
81PHKG10.63343782
82PHKG20.63343782
83MAP2K40.62446174
84IRAK10.61041322
85NEK60.60838390
86UHMK10.60321324
87CDK50.59614083
88CAMKK20.59592208
89FGR0.59548515
90TAOK30.58643204
91NUAK10.57950054
92IRAK30.57720857
93CAMK1G0.57520784
94GRK50.54660353
95EIF2AK30.52426079
96CAMK10.52301608
97CAMK2D0.52212123
98CDC70.51370457
99ADRBK10.48763580
100PLK10.48516670
101CDK140.48036405
102DAPK10.47835822
103CSNK1A10.46344612
104PRKG10.45819205
105OXSR10.44636554
106CAMK40.44285978
107MAPK70.43241073
108NME10.43171325
109BRAF0.41785702
110TAOK20.41577185
111PRKACA0.41504921
112TGFBR10.41037947
113RPS6KA50.40396141
114PLK30.40216271
115CDK180.38229512
116CSNK1D0.36110573
117PLK40.35071989
118CAMK2G0.34934494
119OBSCN0.34474150
120TSSK60.34327339
121ATM0.34222763
122CDK150.33842883
123PRKACB0.32992586
124CDK11A0.32810594
125LYN0.32664351
126BLK0.32633454
127PRKCB0.30955495
128MAP3K60.30714556
129CSNK1E0.29415463
130FLT30.27897174
131TLK10.27878283
132SYK0.27866949
133PRKCZ0.27640846
134WEE10.27359318
135NEK10.27141528
136ACVR1B0.26912405
137PRKDC0.26705598
138CDK190.25298295
139RPS6KA20.25252800
140IKBKE0.25210788
141RPS6KB10.24490708

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.39833809
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.70237887
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.52206083
4Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.34982577
5Steroid biosynthesis_Homo sapiens_hsa001002.34783693
6Morphine addiction_Homo sapiens_hsa050322.33819686
7Taste transduction_Homo sapiens_hsa047422.20660580
8Serotonergic synapse_Homo sapiens_hsa047262.16087962
9Glutamatergic synapse_Homo sapiens_hsa047242.15831975
10Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.09317073
11Phototransduction_Homo sapiens_hsa047442.06003262
12Circadian entrainment_Homo sapiens_hsa047131.98149727
13GABAergic synapse_Homo sapiens_hsa047271.90588264
14Olfactory transduction_Homo sapiens_hsa047401.90043008
15Propanoate metabolism_Homo sapiens_hsa006401.86887090
16Protein export_Homo sapiens_hsa030601.85425167
17Synaptic vesicle cycle_Homo sapiens_hsa047211.83067326
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.70303173
19Amphetamine addiction_Homo sapiens_hsa050311.67760970
20Butanoate metabolism_Homo sapiens_hsa006501.65077325
21Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.64612331
22Non-homologous end-joining_Homo sapiens_hsa034501.58429238
23Collecting duct acid secretion_Homo sapiens_hsa049661.57127536
24Axon guidance_Homo sapiens_hsa043601.52091808
25Long-term depression_Homo sapiens_hsa047301.51708587
26Dopaminergic synapse_Homo sapiens_hsa047281.50572773
27Calcium signaling pathway_Homo sapiens_hsa040201.44492254
28Long-term potentiation_Homo sapiens_hsa047201.43843895
29Cocaine addiction_Homo sapiens_hsa050301.42892555
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.41690421
31Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.39843334
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.36346125
33Autoimmune thyroid disease_Homo sapiens_hsa053201.34037652
34Renin secretion_Homo sapiens_hsa049241.32819988
35Cholinergic synapse_Homo sapiens_hsa047251.30202061
36Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.28720673
37Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.27724086
38Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.27175598
39Salivary secretion_Homo sapiens_hsa049701.23974930
40Rheumatoid arthritis_Homo sapiens_hsa053231.23613552
41Graft-versus-host disease_Homo sapiens_hsa053321.23323896
42Insulin secretion_Homo sapiens_hsa049111.20066768
43Oxidative phosphorylation_Homo sapiens_hsa001901.18183153
44Allograft rejection_Homo sapiens_hsa053301.16172572
45Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.15168692
46Linoleic acid metabolism_Homo sapiens_hsa005911.14318146
47alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.14177273
48Nitrogen metabolism_Homo sapiens_hsa009101.09962412
49RNA polymerase_Homo sapiens_hsa030201.09592034
50Fanconi anemia pathway_Homo sapiens_hsa034601.09268077
51Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.07221289
52Mismatch repair_Homo sapiens_hsa034301.03860573
53African trypanosomiasis_Homo sapiens_hsa051431.03588939
54Peroxisome_Homo sapiens_hsa041461.02760928
55Oxytocin signaling pathway_Homo sapiens_hsa049211.02293231
56Type I diabetes mellitus_Homo sapiens_hsa049401.02216839
57Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.00372341
58Aldosterone synthesis and secretion_Homo sapiens_hsa049250.95776343
59Fatty acid elongation_Homo sapiens_hsa000620.95277398
60Homologous recombination_Homo sapiens_hsa034400.93345199
61Alzheimers disease_Homo sapiens_hsa050100.91561312
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.90337886
63cAMP signaling pathway_Homo sapiens_hsa040240.88517034
64Wnt signaling pathway_Homo sapiens_hsa043100.88155255
65Primary bile acid biosynthesis_Homo sapiens_hsa001200.87056335
66Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.85365739
67Asthma_Homo sapiens_hsa053100.84617236
68GnRH signaling pathway_Homo sapiens_hsa049120.84129352
69Vibrio cholerae infection_Homo sapiens_hsa051100.83651387
70Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.78909876
71Intestinal immune network for IgA production_Homo sapiens_hsa046720.77074731
72Phagosome_Homo sapiens_hsa041450.77003097
73Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.76970665
74Melanogenesis_Homo sapiens_hsa049160.75539726
75Tryptophan metabolism_Homo sapiens_hsa003800.75102622
76Gap junction_Homo sapiens_hsa045400.74961656
77Ether lipid metabolism_Homo sapiens_hsa005650.74382366
78Ovarian steroidogenesis_Homo sapiens_hsa049130.73918765
79ErbB signaling pathway_Homo sapiens_hsa040120.73360237
80Nucleotide excision repair_Homo sapiens_hsa034200.73115353
81Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.72934395
82Parkinsons disease_Homo sapiens_hsa050120.72228237
83Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.71974087
84Gastric acid secretion_Homo sapiens_hsa049710.71476741
85Huntingtons disease_Homo sapiens_hsa050160.70868958
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.69862078
87Alcoholism_Homo sapiens_hsa050340.69813980
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.69153807
89Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.67779751
90beta-Alanine metabolism_Homo sapiens_hsa004100.67038708
91Sphingolipid metabolism_Homo sapiens_hsa006000.66295481
92Pyruvate metabolism_Homo sapiens_hsa006200.66219209
93Selenocompound metabolism_Homo sapiens_hsa004500.66030643
94Base excision repair_Homo sapiens_hsa034100.64903539
95MAPK signaling pathway_Homo sapiens_hsa040100.64591354
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64195864
97Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.63632302
98Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.60297377
99Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60234776
100Circadian rhythm_Homo sapiens_hsa047100.59802998
101Fatty acid metabolism_Homo sapiens_hsa012120.58654855
102Ras signaling pathway_Homo sapiens_hsa040140.57898267
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57778126
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.57158362
105Oocyte meiosis_Homo sapiens_hsa041140.56533379
106Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56346102
107Basal cell carcinoma_Homo sapiens_hsa052170.56102922
108Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.56021894
109Cardiac muscle contraction_Homo sapiens_hsa042600.55963050
110Steroid hormone biosynthesis_Homo sapiens_hsa001400.55177169
111cGMP-PKG signaling pathway_Homo sapiens_hsa040220.54934326
112Metabolic pathways_Homo sapiens_hsa011000.52900733
113Choline metabolism in cancer_Homo sapiens_hsa052310.52536264
114Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.51853375
115Cysteine and methionine metabolism_Homo sapiens_hsa002700.51694707
116Chemokine signaling pathway_Homo sapiens_hsa040620.51429357
117NF-kappa B signaling pathway_Homo sapiens_hsa040640.51126809
118Retinol metabolism_Homo sapiens_hsa008300.51085649
119Purine metabolism_Homo sapiens_hsa002300.50881758
120Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.49811257
121RNA transport_Homo sapiens_hsa030130.49388917
122Hematopoietic cell lineage_Homo sapiens_hsa046400.49367701
123Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49343411
124Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.48655909
125Hedgehog signaling pathway_Homo sapiens_hsa043400.47921690
126Caffeine metabolism_Homo sapiens_hsa002320.47630083
127Hippo signaling pathway_Homo sapiens_hsa043900.46425832
128Toll-like receptor signaling pathway_Homo sapiens_hsa046200.45037163
129Spliceosome_Homo sapiens_hsa030400.44717778
130Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44563735
131Chemical carcinogenesis_Homo sapiens_hsa052040.43936066
132Measles_Homo sapiens_hsa051620.43575897
133Arginine and proline metabolism_Homo sapiens_hsa003300.43540365
134RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.42084697
135Dilated cardiomyopathy_Homo sapiens_hsa054140.41567466
136Arachidonic acid metabolism_Homo sapiens_hsa005900.41250701
137Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41197908
138Melanoma_Homo sapiens_hsa052180.40571807
139Folate biosynthesis_Homo sapiens_hsa007900.38094342
140Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36637678
141Regulation of autophagy_Homo sapiens_hsa041400.36496112
142Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.35406120
143Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.35200335
144Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.34425522
145Basal transcription factors_Homo sapiens_hsa030220.33299478
146RNA degradation_Homo sapiens_hsa030180.32663106
147Inositol phosphate metabolism_Homo sapiens_hsa005620.32343667
148Type II diabetes mellitus_Homo sapiens_hsa049300.32098754
149NOD-like receptor signaling pathway_Homo sapiens_hsa046210.30769046
150Tuberculosis_Homo sapiens_hsa051520.28778684

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