

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.97527884 |
| 2 | negative regulation of cell killing (GO:0031342) | 5.67740293 |
| 3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.67740293 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.65459967 |
| 5 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 5.46794024 |
| 6 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.21120879 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.19159120 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.19159120 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.19159120 |
| 10 | positive regulation by symbiont of host defense response (GO:0052509) | 5.19159120 |
| 11 | modulation by symbiont of host defense response (GO:0052031) | 5.19159120 |
| 12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.19159120 |
| 13 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.07671949 |
| 14 | macrophage activation involved in immune response (GO:0002281) | 4.71304712 |
| 15 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.54693837 |
| 16 | detection of other organism (GO:0098543) | 4.49747192 |
| 17 | regulation of gamma-delta T cell activation (GO:0046643) | 4.30716967 |
| 18 | cellular response to type I interferon (GO:0071357) | 4.28352993 |
| 19 | type I interferon signaling pathway (GO:0060337) | 4.28352993 |
| 20 | detection of bacterium (GO:0016045) | 4.27169285 |
| 21 | response to type I interferon (GO:0034340) | 4.27122493 |
| 22 | neutrophil activation involved in immune response (GO:0002283) | 4.21186485 |
| 23 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.14215196 |
| 24 | response to peptidoglycan (GO:0032494) | 4.12463493 |
| 25 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.08097327 |
| 26 | detection of molecule of bacterial origin (GO:0032490) | 4.06143445 |
| 27 | negative regulation of interleukin-12 production (GO:0032695) | 4.05204780 |
| 28 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.00054112 |
| 29 | detection of external biotic stimulus (GO:0098581) | 3.96554134 |
| 30 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.84200072 |
| 31 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.76758546 |
| 32 | cellular extravasation (GO:0045123) | 3.76170298 |
| 33 | leukocyte aggregation (GO:0070486) | 3.75671047 |
| 34 | B cell receptor signaling pathway (GO:0050853) | 3.74299780 |
| 35 | immunoglobulin mediated immune response (GO:0016064) | 3.73924746 |
| 36 | response to interleukin-15 (GO:0070672) | 3.68108537 |
| 37 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.63488362 |
| 38 | response to host immune response (GO:0052572) | 3.63488362 |
| 39 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.56918072 |
| 40 | germinal center formation (GO:0002467) | 3.51895354 |
| 41 | negative regulation of T cell mediated immunity (GO:0002710) | 3.51412505 |
| 42 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.45082855 |
| 43 | cellular response to interleukin-15 (GO:0071350) | 3.41600211 |
| 44 | microglial cell activation (GO:0001774) | 3.41007101 |
| 45 | detection of biotic stimulus (GO:0009595) | 3.39473453 |
| 46 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.37828839 |
| 47 | response to host (GO:0075136) | 3.37828839 |
| 48 | response to host defenses (GO:0052200) | 3.37828839 |
| 49 | regulation of T cell tolerance induction (GO:0002664) | 3.32327707 |
| 50 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.31026262 |
| 51 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.29867733 |
| 52 | macrophage activation (GO:0042116) | 3.29771265 |
| 53 | defense response to protozoan (GO:0042832) | 3.28626189 |
| 54 | myeloid cell activation involved in immune response (GO:0002275) | 3.28268741 |
| 55 | neutrophil activation (GO:0042119) | 3.27665695 |
| 56 | T cell migration (GO:0072678) | 3.23818358 |
| 57 | respiratory burst (GO:0045730) | 3.22153812 |
| 58 | negative thymic T cell selection (GO:0045060) | 3.20851531 |
| 59 | regulation of tolerance induction (GO:0002643) | 3.16087412 |
| 60 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.15408423 |
| 61 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.12809571 |
| 62 | negative T cell selection (GO:0043383) | 3.12650167 |
| 63 | positive regulation of interferon-alpha production (GO:0032727) | 3.10558499 |
| 64 | positive regulation of type 2 immune response (GO:0002830) | 3.10537579 |
| 65 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.09355915 |
| 66 | positive thymic T cell selection (GO:0045059) | 3.05711824 |
| 67 | granulocyte activation (GO:0036230) | 3.05618837 |
| 68 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.05176383 |
| 69 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.03109823 |
| 70 | regulation of B cell differentiation (GO:0045577) | 3.02480135 |
| 71 | regulation of interferon-alpha production (GO:0032647) | 3.01185109 |
| 72 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.99817876 |
| 73 | T cell selection (GO:0045058) | 2.97559935 |
| 74 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.97546051 |
| 75 | response to protozoan (GO:0001562) | 2.97469358 |
| 76 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.96500188 |
| 77 | response to interferon-alpha (GO:0035455) | 2.96352945 |
| 78 | B cell mediated immunity (GO:0019724) | 2.95557602 |
| 79 | response to muramyl dipeptide (GO:0032495) | 2.93622663 |
| 80 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.93305037 |
| 81 | positive regulation of B cell differentiation (GO:0045579) | 2.91198845 |
| 82 | regulation of regulatory T cell differentiation (GO:0045589) | 2.91183409 |
| 83 | thymic T cell selection (GO:0045061) | 2.90330288 |
| 84 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.88234716 |
| 85 | regulation of mast cell degranulation (GO:0043304) | 2.87334268 |
| 86 | regulation of necroptotic process (GO:0060544) | 2.86962686 |
| 87 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.85750571 |
| 88 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.85750571 |
| 89 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.84157476 |
| 90 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.83746751 |
| 91 | neutrophil mediated immunity (GO:0002446) | 2.81654646 |
| 92 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.81056322 |
| 93 | regulation of type 2 immune response (GO:0002828) | 2.81003264 |
| 94 | regulation of antigen processing and presentation (GO:0002577) | 2.80587585 |
| 95 | dendritic cell chemotaxis (GO:0002407) | 2.79916083 |
| 96 | positive regulation of tolerance induction (GO:0002645) | 2.78539657 |
| 97 | NIK/NF-kappaB signaling (GO:0038061) | 2.77111706 |
| 98 | negative regulation of innate immune response (GO:0045824) | 2.76596078 |
| 99 | negative regulation of type 2 immune response (GO:0002829) | 2.76041832 |
| 100 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.74378327 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.05106624 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.24617498 |
| 3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.00227069 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.86046601 |
| 5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.64982258 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.39635412 |
| 7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.17746695 |
| 8 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.96405443 |
| 9 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.94221100 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.93947019 |
| 11 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.71385228 |
| 12 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.62442696 |
| 13 | * RUNX_20019798_ChIP-Seq_JUKART_Human | 2.60208160 |
| 14 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.53847955 |
| 15 | MYB_26560356_Chip-Seq_TH2_Human | 2.32682358 |
| 16 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.31929317 |
| 17 | MAF_26560356_Chip-Seq_TH1_Human | 2.31824999 |
| 18 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.29031669 |
| 19 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.27013400 |
| 20 | MYC_22102868_ChIP-Seq_BL_Human | 2.25318269 |
| 21 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.25174987 |
| 22 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.24314953 |
| 23 | * VDR_24763502_ChIP-Seq_THP-1_Human | 2.24017399 |
| 24 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.23040961 |
| 25 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.21159035 |
| 26 | * SPI1_23127762_ChIP-Seq_K562_Human | 2.20941715 |
| 27 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.20645428 |
| 28 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.18610311 |
| 29 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.14241635 |
| 30 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.10186803 |
| 31 | * MYB_26560356_Chip-Seq_TH1_Human | 2.04406650 |
| 32 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.01198102 |
| 33 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.98200685 |
| 34 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.95446624 |
| 35 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.94782512 |
| 36 | UTX_26944678_Chip-Seq_JUKART_Human | 1.94749418 |
| 37 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.92162653 |
| 38 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.90966391 |
| 39 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.90505457 |
| 40 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.81308220 |
| 41 | MAF_26560356_Chip-Seq_TH2_Human | 1.73270110 |
| 42 | GATA1_22025678_ChIP-Seq_K562_Human | 1.72177526 |
| 43 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.72121373 |
| 44 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.64988751 |
| 45 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.61478137 |
| 46 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.55924257 |
| 47 | * VDR_24787735_ChIP-Seq_THP-1_Human | 1.55621469 |
| 48 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.49155361 |
| 49 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.45899929 |
| 50 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.40312276 |
| 51 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.39669794 |
| 52 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.39209937 |
| 53 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38945456 |
| 54 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.35880359 |
| 55 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.31735646 |
| 56 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.29116946 |
| 57 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.27862495 |
| 58 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.24820287 |
| 59 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.23373626 |
| 60 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.22213475 |
| 61 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.22186133 |
| 62 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.22120442 |
| 63 | GATA3_26560356_Chip-Seq_TH2_Human | 1.16050572 |
| 64 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.14550807 |
| 65 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.13900984 |
| 66 | GATA1_19941826_ChIP-Seq_K562_Human | 1.13853216 |
| 67 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.13641291 |
| 68 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.13003213 |
| 69 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.12556747 |
| 70 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.11457669 |
| 71 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.10128110 |
| 72 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.06335924 |
| 73 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.04742658 |
| 74 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04547196 |
| 75 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.04099156 |
| 76 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.03842241 |
| 77 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03647312 |
| 78 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03479670 |
| 79 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.03385801 |
| 80 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02531822 |
| 81 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.01583125 |
| 82 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.01504219 |
| 83 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01466069 |
| 84 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.01283129 |
| 85 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00278192 |
| 86 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.00250144 |
| 87 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.98769227 |
| 88 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.96636945 |
| 89 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95519198 |
| 90 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.93720660 |
| 91 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.93161341 |
| 92 | GATA2_19941826_ChIP-Seq_K562_Human | 0.92378728 |
| 93 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.91676173 |
| 94 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.89283629 |
| 95 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.86980985 |
| 96 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.86249657 |
| 97 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.85036011 |
| 98 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.84378264 |
| 99 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.84240035 |
| 100 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.83126785 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.51984704 |
| 2 | MP0003303_peritoneal_inflammation | 3.82502616 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.66887950 |
| 4 | MP0003436_decreased_susceptibility_to | 3.56778743 |
| 5 | MP0005387_immune_system_phenotype | 2.98739498 |
| 6 | MP0001790_abnormal_immune_system | 2.98739498 |
| 7 | MP0009785_altered_susceptibility_to | 2.93177302 |
| 8 | MP0001800_abnormal_humoral_immune | 2.92449710 |
| 9 | MP0000685_abnormal_immune_system | 2.78862069 |
| 10 | MP0005671_abnormal_response_to | 2.77802863 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.77613389 |
| 12 | MP0002419_abnormal_innate_immunity | 2.75789612 |
| 13 | MP0005025_abnormal_response_to | 2.69813039 |
| 14 | MP0003763_abnormal_thymus_physiology | 2.58197053 |
| 15 | MP0003300_gastrointestinal_ulcer | 2.50706714 |
| 16 | MP0002723_abnormal_immune_serum | 2.48944016 |
| 17 | MP0002452_abnormal_antigen_presenting | 2.48257625 |
| 18 | MP0002420_abnormal_adaptive_immunity | 2.38059362 |
| 19 | MP0001819_abnormal_immune_cell | 2.35858948 |
| 20 | MP0002148_abnormal_hypersensitivity_rea | 2.31610088 |
| 21 | MP0006082_CNS_inflammation | 2.31562903 |
| 22 | MP0005451_abnormal_body_composition | 2.09621946 |
| 23 | MP0003191_abnormal_cellular_cholesterol | 2.02162953 |
| 24 | MP0002405_respiratory_system_inflammati | 1.96876770 |
| 25 | MP0001533_abnormal_skeleton_physiology | 1.93838120 |
| 26 | MP0004947_skin_inflammation | 1.91101893 |
| 27 | MP0010155_abnormal_intestine_physiology | 1.88442573 |
| 28 | MP0002398_abnormal_bone_marrow | 1.83653475 |
| 29 | MP0000716_abnormal_immune_system | 1.82003494 |
| 30 | MP0002132_abnormal_respiratory_system | 1.76049593 |
| 31 | MP0001845_abnormal_inflammatory_respons | 1.75004028 |
| 32 | MP0008260_abnormal_autophagy | 1.72537054 |
| 33 | MP0003828_pulmonary_edema | 1.64763530 |
| 34 | MP0009333_abnormal_splenocyte_physiolog | 1.63177051 |
| 35 | MP0004381_abnormal_hair_follicle | 1.62823474 |
| 36 | MP0004510_myositis | 1.55054664 |
| 37 | MP0005464_abnormal_platelet_physiology | 1.54650695 |
| 38 | MP0002722_abnormal_immune_system | 1.48775578 |
| 39 | MP0000689_abnormal_spleen_morphology | 1.48592177 |
| 40 | MP0002166_altered_tumor_susceptibility | 1.48150791 |
| 41 | MP0002429_abnormal_blood_cell | 1.42322718 |
| 42 | MP0000858_altered_metastatic_potential | 1.40576038 |
| 43 | MP0004883_abnormal_blood_vessel | 1.40426827 |
| 44 | MP0005310_abnormal_salivary_gland | 1.39840357 |
| 45 | MP0008469_abnormal_protein_level | 1.39731005 |
| 46 | MP0009278_abnormal_bone_marrow | 1.38106749 |
| 47 | MP0002998_abnormal_bone_remodeling | 1.37549070 |
| 48 | MP0000703_abnormal_thymus_morphology | 1.36998457 |
| 49 | MP0000465_gastrointestinal_hemorrhage | 1.35407651 |
| 50 | MP0003866_abnormal_defecation | 1.32360401 |
| 51 | MP0001545_abnormal_hematopoietic_system | 1.30494723 |
| 52 | MP0005397_hematopoietic_system_phenotyp | 1.30494723 |
| 53 | MP0003183_abnormal_peptide_metabolism | 1.27681753 |
| 54 | MP0009764_decreased_sensitivity_to | 1.27516455 |
| 55 | MP0003172_abnormal_lysosome_physiology | 1.27361327 |
| 56 | MP0002138_abnormal_hepatobiliary_system | 1.24440662 |
| 57 | MP0005164_abnormal_response_to | 1.23792075 |
| 58 | MP0003075_altered_response_to | 1.21882584 |
| 59 | MP0001853_heart_inflammation | 1.21524861 |
| 60 | MP0005166_decreased_susceptibility_to | 1.21296908 |
| 61 | MP0001851_eye_inflammation | 1.19821891 |
| 62 | MP0008004_abnormal_stomach_pH | 1.18122027 |
| 63 | MP0002396_abnormal_hematopoietic_system | 1.12822536 |
| 64 | MP0001873_stomach_inflammation | 1.12457840 |
| 65 | MP0003453_abnormal_keratinocyte_physiol | 1.06222794 |
| 66 | MP0002277_abnormal_respiratory_mucosa | 1.04248825 |
| 67 | MP0003091_abnormal_cell_migration | 1.03596730 |
| 68 | MP0005058_abnormal_lysosome_morphology | 1.03480432 |
| 69 | MP0003045_fibrosis | 1.02063139 |
| 70 | MP0003448_altered_tumor_morphology | 0.98642740 |
| 71 | MP0000343_altered_response_to | 0.98031746 |
| 72 | MP0003690_abnormal_glial_cell | 0.97079819 |
| 73 | MP0002006_tumorigenesis | 0.91417839 |
| 74 | MP0002933_joint_inflammation | 0.90211836 |
| 75 | MP0004264_abnormal_extraembryonic_tissu | 0.89556954 |
| 76 | MP0009840_abnormal_foam_cell | 0.86180094 |
| 77 | MP0004808_abnormal_hematopoietic_stem | 0.83566501 |
| 78 | MP0000249_abnormal_blood_vessel | 0.79105496 |
| 79 | MP0009763_increased_sensitivity_to | 0.78045154 |
| 80 | MP0005390_skeleton_phenotype | 0.76783601 |
| 81 | MP0005666_abnormal_adipose_tissue | 0.75961916 |
| 82 | MP0003656_abnormal_erythrocyte_physiolo | 0.74797917 |
| 83 | MP0004185_abnormal_adipocyte_glucose | 0.73282433 |
| 84 | MP0002332_abnormal_exercise_endurance | 0.71671185 |
| 85 | MP0010234_abnormal_vibrissa_follicle | 0.71324428 |
| 86 | MP0003806_abnormal_nucleotide_metabolis | 0.70681746 |
| 87 | MP0009115_abnormal_fat_cell | 0.69736309 |
| 88 | MP0001663_abnormal_digestive_system | 0.69632406 |
| 89 | MP0003795_abnormal_bone_structure | 0.68775765 |
| 90 | MP0003566_abnormal_cell_adhesion | 0.67543188 |
| 91 | MP0000490_abnormal_crypts_of | 0.65687896 |
| 92 | MP0000604_amyloidosis | 0.64689228 |
| 93 | MP0003221_abnormal_cardiomyocyte_apopto | 0.64369102 |
| 94 | MP0008874_decreased_physiological_sensi | 0.63794318 |
| 95 | MP0001849_ear_inflammation | 0.59999904 |
| 96 | MP0005075_abnormal_melanosome_morpholog | 0.59105933 |
| 97 | MP0005076_abnormal_cell_differentiation | 0.59100630 |
| 98 | MP0004484_altered_response_of | 0.56864301 |
| 99 | MP0005023_abnormal_wound_healing | 0.56495876 |
| 100 | MP0002009_preneoplasia | 0.55836172 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 5.99076274 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 5.22940211 |
| 3 | Recurrent abscess formation (HP:0002722) | 5.11529522 |
| 4 | Myositis (HP:0100614) | 5.00499138 |
| 5 | Orchitis (HP:0100796) | 4.92434443 |
| 6 | Retrobulbar optic neuritis (HP:0100654) | 4.70579512 |
| 7 | Optic neuritis (HP:0100653) | 4.70579512 |
| 8 | Abnormality of macrophages (HP:0004311) | 4.66651850 |
| 9 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.10802596 |
| 10 | Mediastinal lymphadenopathy (HP:0100721) | 3.92091010 |
| 11 | Gastrointestinal infarctions (HP:0005244) | 3.89452356 |
| 12 | Recurrent fungal infections (HP:0002841) | 3.85061170 |
| 13 | Meningitis (HP:0001287) | 3.82444751 |
| 14 | Stomatitis (HP:0010280) | 3.78079655 |
| 15 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.77621054 |
| 16 | Vasculitis (HP:0002633) | 3.66620979 |
| 17 | Keratoconjunctivitis sicca (HP:0001097) | 3.65491714 |
| 18 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.53617214 |
| 19 | T lymphocytopenia (HP:0005403) | 3.47352513 |
| 20 | Recurrent skin infections (HP:0001581) | 3.47012196 |
| 21 | Spontaneous hematomas (HP:0007420) | 3.44458192 |
| 22 | Chronic obstructive pulmonary disease (HP:0006510) | 3.40460708 |
| 23 | Obstructive lung disease (HP:0006536) | 3.40460708 |
| 24 | Gingivitis (HP:0000230) | 3.39379153 |
| 25 | Increased IgE level (HP:0003212) | 3.36122321 |
| 26 | Abnormality of T cell number (HP:0011839) | 3.31758433 |
| 27 | Keratoconjunctivitis (HP:0001096) | 3.31546749 |
| 28 | Recurrent viral infections (HP:0004429) | 3.26496469 |
| 29 | Cellulitis (HP:0100658) | 3.23983435 |
| 30 | Colitis (HP:0002583) | 3.20480557 |
| 31 | Encephalitis (HP:0002383) | 3.18465338 |
| 32 | Inflammation of the large intestine (HP:0002037) | 3.17300789 |
| 33 | Recurrent cutaneous fungal infections (HP:0011370) | 3.12337052 |
| 34 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.12337052 |
| 35 | Gastrointestinal inflammation (HP:0004386) | 3.06282964 |
| 36 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.98546339 |
| 37 | Urticaria (HP:0001025) | 2.92583273 |
| 38 | Pulmonary infiltrates (HP:0002113) | 2.88900161 |
| 39 | Hemoptysis (HP:0002105) | 2.85038624 |
| 40 | Chest pain (HP:0100749) | 2.77180791 |
| 41 | Prolonged bleeding time (HP:0003010) | 2.75892067 |
| 42 | Recurrent bronchitis (HP:0002837) | 2.73779683 |
| 43 | Abnormality of T cells (HP:0002843) | 2.69369501 |
| 44 | Arterial thrombosis (HP:0004420) | 2.67443052 |
| 45 | Granulocytopenia (HP:0001913) | 2.63463905 |
| 46 | Osteomyelitis (HP:0002754) | 2.63145164 |
| 47 | Gastrointestinal stroma tumor (HP:0100723) | 2.62356077 |
| 48 | Leukocytosis (HP:0001974) | 2.60005796 |
| 49 | Panhypogammaglobulinemia (HP:0003139) | 2.55888191 |
| 50 | Gingival bleeding (HP:0000225) | 2.52864450 |
| 51 | Pustule (HP:0200039) | 2.52531477 |
| 52 | Lymphopenia (HP:0001888) | 2.49990818 |
| 53 | Agammaglobulinemia (HP:0004432) | 2.47335164 |
| 54 | Pulmonary embolism (HP:0002204) | 2.45420500 |
| 55 | Increased IgM level (HP:0003496) | 2.44777314 |
| 56 | Anorexia (HP:0002039) | 2.40170830 |
| 57 | Autoimmune hemolytic anemia (HP:0001890) | 2.39514521 |
| 58 | Hypochromic microcytic anemia (HP:0004840) | 2.39188801 |
| 59 | Hypochromic anemia (HP:0001931) | 2.39158677 |
| 60 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.39133192 |
| 61 | Interstitial pulmonary disease (HP:0006530) | 2.38298062 |
| 62 | Epistaxis (HP:0000421) | 2.38128886 |
| 63 | Eosinophilia (HP:0001880) | 2.37296769 |
| 64 | Papilledema (HP:0001085) | 2.30371113 |
| 65 | Gangrene (HP:0100758) | 2.28757097 |
| 66 | Sepsis (HP:0100806) | 2.26324438 |
| 67 | Hypergammaglobulinemia (HP:0010702) | 2.18082867 |
| 68 | IgM deficiency (HP:0002850) | 2.17584062 |
| 69 | Skin ulcer (HP:0200042) | 2.16235449 |
| 70 | Abnormality of T cell physiology (HP:0011840) | 2.15735439 |
| 71 | Abnormality of the pleura (HP:0002103) | 2.15453951 |
| 72 | Acute hepatic failure (HP:0006554) | 2.14768959 |
| 73 | Episodic fever (HP:0001954) | 2.13736542 |
| 74 | Amyloidosis (HP:0011034) | 2.13413524 |
| 75 | Peritonitis (HP:0002586) | 2.12895171 |
| 76 | Premature loss of primary teeth (HP:0006323) | 2.11071658 |
| 77 | Papilloma (HP:0012740) | 2.09720551 |
| 78 | Verrucae (HP:0200043) | 2.09720551 |
| 79 | Slow saccadic eye movements (HP:0000514) | 2.08736264 |
| 80 | Nasal polyposis (HP:0100582) | 2.05818732 |
| 81 | Chronic otitis media (HP:0000389) | 2.05185297 |
| 82 | Viral hepatitis (HP:0006562) | 2.00807958 |
| 83 | Restrictive lung disease (HP:0002091) | 2.00073048 |
| 84 | Recurrent sinusitis (HP:0011108) | 1.98738911 |
| 85 | Abnormality of the endocardium (HP:0004306) | 1.98647605 |
| 86 | Petechiae (HP:0000967) | 1.98431470 |
| 87 | Abnormality of the peritoneum (HP:0002585) | 1.98366060 |
| 88 | Joint swelling (HP:0001386) | 1.95568268 |
| 89 | Glomerulopathy (HP:0100820) | 1.93664465 |
| 90 | Abnormality of the nasal mucosa (HP:0000433) | 1.93289809 |
| 91 | Microcytic anemia (HP:0001935) | 1.89572721 |
| 92 | Loss of speech (HP:0002371) | 1.89384905 |
| 93 | Systemic lupus erythematosus (HP:0002725) | 1.89355075 |
| 94 | Skin rash (HP:0000988) | 1.89178094 |
| 95 | Polyneuropathy (HP:0001271) | 1.89145123 |
| 96 | Autoimmune thrombocytopenia (HP:0001973) | 1.89143429 |
| 97 | Purpura (HP:0000979) | 1.88946235 |
| 98 | Abnormality of glycolipid metabolism (HP:0010969) | 1.88784034 |
| 99 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.88784034 |
| 100 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.88784034 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.39047532 |
| 2 | MAP4K1 | 3.83677952 |
| 3 | ERN1 | 3.19436675 |
| 4 | BLK | 3.07383933 |
| 5 | IRAK4 | 2.91789998 |
| 6 | TYK2 | 2.90314740 |
| 7 | PRPF4B | 2.72572404 |
| 8 | CSK | 2.52208847 |
| 9 | MAP2K3 | 2.25822918 |
| 10 | EPHB1 | 2.15154623 |
| 11 | ZAP70 | 2.02752673 |
| 12 | JAK3 | 1.98133766 |
| 13 | MAP3K14 | 1.91214540 |
| 14 | BTK | 1.89667956 |
| 15 | MAP3K13 | 1.85536336 |
| 16 | IKBKE | 1.85098378 |
| 17 | FES | 1.83453259 |
| 18 | GRK6 | 1.77819601 |
| 19 | JAK1 | 1.74104203 |
| 20 | MAP3K3 | 1.69641936 |
| 21 | TXK | 1.63537285 |
| 22 | TNK2 | 1.62420650 |
| 23 | TAOK1 | 1.51313463 |
| 24 | SYK | 1.50980684 |
| 25 | MAP3K1 | 1.50599735 |
| 26 | HCK | 1.49765297 |
| 27 | FGFR4 | 1.48804255 |
| 28 | TBK1 | 1.46778536 |
| 29 | TRIB3 | 1.45263921 |
| 30 | MARK3 | 1.42701634 |
| 31 | FGR | 1.42386208 |
| 32 | JAK2 | 1.33086072 |
| 33 | SIK3 | 1.24535904 |
| 34 | LYN | 1.18111799 |
| 35 | FGFR3 | 1.17452661 |
| 36 | KSR2 | 1.16156629 |
| 37 | NLK | 1.13141856 |
| 38 | ITK | 1.11073954 |
| 39 | LCK | 1.05867077 |
| 40 | MAP3K11 | 1.03979123 |
| 41 | BMPR2 | 1.02949708 |
| 42 | YES1 | 1.02347151 |
| 43 | CSF1R | 1.01815789 |
| 44 | IRAK1 | 1.01209896 |
| 45 | RIPK1 | 1.00489394 |
| 46 | TGFBR2 | 0.95305531 |
| 47 | IKBKB | 0.94298328 |
| 48 | SIK1 | 0.94274344 |
| 49 | STK10 | 0.94162066 |
| 50 | MARK2 | 0.93723643 |
| 51 | LRRK2 | 0.90680545 |
| 52 | CDC42BPA | 0.89404430 |
| 53 | IRAK2 | 0.88719558 |
| 54 | MAP3K2 | 0.86812781 |
| 55 | PDK1 | 0.85306715 |
| 56 | TAOK3 | 0.83713148 |
| 57 | MATK | 0.83645967 |
| 58 | CDK12 | 0.81511773 |
| 59 | KIT | 0.81047947 |
| 60 | PDPK1 | 0.80813339 |
| 61 | TAOK2 | 0.80352297 |
| 62 | MAP3K10 | 0.79449541 |
| 63 | TEC | 0.77063489 |
| 64 | HIPK2 | 0.75374212 |
| 65 | EPHA3 | 0.74449146 |
| 66 | PIK3CG | 0.74188651 |
| 67 | SMG1 | 0.70419925 |
| 68 | MAPK12 | 0.69988713 |
| 69 | PTK6 | 0.67006174 |
| 70 | SGK3 | 0.65623988 |
| 71 | MAP3K6 | 0.62983481 |
| 72 | NME2 | 0.62797354 |
| 73 | PRKD2 | 0.62216385 |
| 74 | PRKCQ | 0.58186511 |
| 75 | IRAK3 | 0.55445533 |
| 76 | STK38 | 0.53001441 |
| 77 | SGK2 | 0.52789177 |
| 78 | MAPK7 | 0.52714251 |
| 79 | MAP3K7 | 0.51989910 |
| 80 | RET | 0.50369150 |
| 81 | FYN | 0.47602717 |
| 82 | MAP3K5 | 0.46787844 |
| 83 | RPS6KL1 | 0.45550285 |
| 84 | RPS6KC1 | 0.45550285 |
| 85 | MAPKAPK2 | 0.42907616 |
| 86 | PIM1 | 0.42201017 |
| 87 | GRK7 | 0.41786527 |
| 88 | SIK2 | 0.41506821 |
| 89 | CDK4 | 0.40968490 |
| 90 | MOS | 0.39229514 |
| 91 | CHUK | 0.38218340 |
| 92 | PTK2B | 0.37963428 |
| 93 | PKN2 | 0.37314299 |
| 94 | MAPK11 | 0.36699018 |
| 95 | PDGFRB | 0.35514443 |
| 96 | RPS6KA6 | 0.34182885 |
| 97 | MAP2K6 | 0.32218691 |
| 98 | MST1R | 0.31312962 |
| 99 | DYRK1B | 0.31226858 |
| 100 | MELK | 0.29441671 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.77868365 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.71384574 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 2.61440770 |
| 4 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.53575022 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.51074948 |
| 6 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.50388452 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.43708381 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.17889764 |
| 9 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.16758953 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.09345177 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.01964356 |
| 12 | Tuberculosis_Homo sapiens_hsa05152 | 1.99315745 |
| 13 | Measles_Homo sapiens_hsa05162 | 1.98058259 |
| 14 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.97197353 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.87821227 |
| 16 | Malaria_Homo sapiens_hsa05144 | 1.86005431 |
| 17 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.77727153 |
| 18 | Influenza A_Homo sapiens_hsa05164 | 1.77386118 |
| 19 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.75033215 |
| 20 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.72200104 |
| 21 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.70761578 |
| 22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.64806388 |
| 23 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.64573135 |
| 24 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.62537500 |
| 25 | Viral myocarditis_Homo sapiens_hsa05416 | 1.62384048 |
| 26 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.60744875 |
| 27 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.58671188 |
| 28 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.53811347 |
| 29 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.52770982 |
| 30 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.52551759 |
| 31 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.49587418 |
| 32 | Asthma_Homo sapiens_hsa05310 | 1.48614925 |
| 33 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.46389964 |
| 34 | Hepatitis C_Homo sapiens_hsa05160 | 1.35460653 |
| 35 | Legionellosis_Homo sapiens_hsa05134 | 1.34010733 |
| 36 | Hepatitis B_Homo sapiens_hsa05161 | 1.28355260 |
| 37 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.28172982 |
| 38 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.28101664 |
| 39 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.24562338 |
| 40 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.16964069 |
| 41 | Phagosome_Homo sapiens_hsa04145 | 1.15995006 |
| 42 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.13893404 |
| 43 | Pertussis_Homo sapiens_hsa05133 | 1.13138945 |
| 44 | Other glycan degradation_Homo sapiens_hsa00511 | 1.08258865 |
| 45 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.04548173 |
| 46 | Apoptosis_Homo sapiens_hsa04210 | 1.03319988 |
| 47 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.00170185 |
| 48 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.97946951 |
| 49 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.96930444 |
| 50 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.95652101 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.95534736 |
| 52 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.94774664 |
| 53 | Platelet activation_Homo sapiens_hsa04611 | 0.94321124 |
| 54 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.91527437 |
| 55 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.90877612 |
| 56 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.88222821 |
| 57 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.78704113 |
| 58 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.78009206 |
| 59 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.77401490 |
| 60 | Endometrial cancer_Homo sapiens_hsa05213 | 0.77228660 |
| 61 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.74185724 |
| 62 | Salmonella infection_Homo sapiens_hsa05132 | 0.72658716 |
| 63 | Shigellosis_Homo sapiens_hsa05131 | 0.72455823 |
| 64 | Insulin resistance_Homo sapiens_hsa04931 | 0.72006614 |
| 65 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.72003472 |
| 66 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.71593084 |
| 67 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.69544604 |
| 68 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.69375924 |
| 69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.68732640 |
| 70 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.68508117 |
| 71 | HTLV-I infection_Homo sapiens_hsa05166 | 0.64154637 |
| 72 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.63701288 |
| 73 | Endocytosis_Homo sapiens_hsa04144 | 0.63641730 |
| 74 | Amoebiasis_Homo sapiens_hsa05146 | 0.62992892 |
| 75 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.62606971 |
| 76 | Prostate cancer_Homo sapiens_hsa05215 | 0.59933565 |
| 77 | Lysosome_Homo sapiens_hsa04142 | 0.59809998 |
| 78 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.58052850 |
| 79 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.55025070 |
| 80 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.53655806 |
| 81 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.53155909 |
| 82 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.51335488 |
| 83 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.50266289 |
| 84 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.50233235 |
| 85 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.48917177 |
| 86 | Thyroid cancer_Homo sapiens_hsa05216 | 0.48747930 |
| 87 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.48734550 |
| 88 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.47536015 |
| 89 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.44448314 |
| 90 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.44024631 |
| 91 | Colorectal cancer_Homo sapiens_hsa05210 | 0.43585559 |
| 92 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.42121513 |
| 93 | Glioma_Homo sapiens_hsa05214 | 0.41800070 |
| 94 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.40405740 |
| 95 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.36844920 |
| 96 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.36696479 |
| 97 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.34907741 |
| 98 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.34068316 |
| 99 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.33485287 |
| 100 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.31429853 |

