

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chromatin remodeling at centromere (GO:0031055) | 5.73523958 |
| 2 | CENP-A containing nucleosome assembly (GO:0034080) | 5.64477216 |
| 3 | DNA strand elongation involved in DNA replication (GO:0006271) | 5.20639715 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.15508564 |
| 5 | telomere maintenance via semi-conservative replication (GO:0032201) | 5.13511406 |
| 6 | DNA replication checkpoint (GO:0000076) | 4.99513830 |
| 7 | DNA strand elongation (GO:0022616) | 4.98332853 |
| 8 | histone exchange (GO:0043486) | 4.63249806 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.55803368 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 4.55803368 |
| 11 | telomere maintenance via recombination (GO:0000722) | 4.44585059 |
| 12 | DNA replication-independent nucleosome organization (GO:0034724) | 4.39153761 |
| 13 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.39153761 |
| 14 | ribosomal small subunit assembly (GO:0000028) | 4.38867433 |
| 15 | viral transcription (GO:0019083) | 4.35631771 |
| 16 | mitotic recombination (GO:0006312) | 4.31636718 |
| 17 | translational termination (GO:0006415) | 4.30362404 |
| 18 | kinetochore organization (GO:0051383) | 4.23834360 |
| 19 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.19871747 |
| 20 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 4.11847192 |
| 21 | maturation of SSU-rRNA (GO:0030490) | 4.08290694 |
| 22 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.97088852 |
| 23 | establishment of integrated proviral latency (GO:0075713) | 3.96984954 |
| 24 | proteasome assembly (GO:0043248) | 3.94197861 |
| 25 | cotranslational protein targeting to membrane (GO:0006613) | 3.93658505 |
| 26 | ribosomal small subunit biogenesis (GO:0042274) | 3.87233173 |
| 27 | protein targeting to ER (GO:0045047) | 3.87048006 |
| 28 | kinetochore assembly (GO:0051382) | 3.76195148 |
| 29 | protein localization to kinetochore (GO:0034501) | 3.73375236 |
| 30 | mitotic sister chromatid segregation (GO:0000070) | 3.71458196 |
| 31 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.70737081 |
| 32 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.70422061 |
| 33 | chaperone-mediated protein transport (GO:0072321) | 3.69619741 |
| 34 | telomere maintenance via telomere lengthening (GO:0010833) | 3.68649813 |
| 35 | DNA ligation (GO:0006266) | 3.68478466 |
| 36 | replication fork processing (GO:0031297) | 3.68453652 |
| 37 | ribosomal large subunit biogenesis (GO:0042273) | 3.64038466 |
| 38 | translational elongation (GO:0006414) | 3.62963157 |
| 39 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.62652049 |
| 40 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.62652049 |
| 41 | protein localization to endoplasmic reticulum (GO:0070972) | 3.59747830 |
| 42 | DNA double-strand break processing (GO:0000729) | 3.57563880 |
| 43 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.54391944 |
| 44 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.53773290 |
| 45 | purine nucleobase biosynthetic process (GO:0009113) | 3.52536544 |
| 46 | DNA replication initiation (GO:0006270) | 3.50429369 |
| 47 | respiratory electron transport chain (GO:0022904) | 3.50377375 |
| 48 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.47993079 |
| 49 | protein K6-linked ubiquitination (GO:0085020) | 3.46613870 |
| 50 | electron transport chain (GO:0022900) | 3.45273372 |
| 51 | DNA unwinding involved in DNA replication (GO:0006268) | 3.41388672 |
| 52 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.41209947 |
| 53 | mitotic metaphase plate congression (GO:0007080) | 3.41169791 |
| 54 | translational initiation (GO:0006413) | 3.40820072 |
| 55 | sister chromatid segregation (GO:0000819) | 3.40218191 |
| 56 | nucleobase biosynthetic process (GO:0046112) | 3.37412429 |
| 57 | cellular protein complex disassembly (GO:0043624) | 3.36439874 |
| 58 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.35363607 |
| 59 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.34812443 |
| 60 | regulation of centriole replication (GO:0046599) | 3.34020199 |
| 61 | spliceosomal snRNP assembly (GO:0000387) | 3.32020343 |
| 62 | protein complex biogenesis (GO:0070271) | 3.31842853 |
| 63 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.31310917 |
| 64 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.30332136 |
| 65 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.27850653 |
| 66 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.27494584 |
| 67 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.27494584 |
| 68 | NADH dehydrogenase complex assembly (GO:0010257) | 3.27494584 |
| 69 | regulation of mitochondrial translation (GO:0070129) | 3.26181747 |
| 70 | viral life cycle (GO:0019058) | 3.23687918 |
| 71 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.22806261 |
| 72 | translation (GO:0006412) | 3.21944549 |
| 73 | chromatin assembly or disassembly (GO:0006333) | 3.21053828 |
| 74 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.20268632 |
| 75 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.17925224 |
| 76 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.17925224 |
| 77 | protein neddylation (GO:0045116) | 3.16796911 |
| 78 | metaphase plate congression (GO:0051310) | 3.16020258 |
| 79 | meiotic chromosome segregation (GO:0045132) | 3.14141813 |
| 80 | recombinational repair (GO:0000725) | 3.14130394 |
| 81 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.14127771 |
| 82 | protein localization to chromosome, centromeric region (GO:0071459) | 3.12805996 |
| 83 | double-strand break repair via homologous recombination (GO:0000724) | 3.10792944 |
| 84 | mitotic chromosome condensation (GO:0007076) | 3.10020768 |
| 85 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.09576232 |
| 86 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.09576232 |
| 87 | negative regulation of ligase activity (GO:0051352) | 3.09017202 |
| 88 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.09017202 |
| 89 | rRNA modification (GO:0000154) | 3.08615179 |
| 90 | termination of RNA polymerase III transcription (GO:0006386) | 3.08420500 |
| 91 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.08420500 |
| 92 | establishment of viral latency (GO:0019043) | 3.03730890 |
| 93 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.01863651 |
| 94 | DNA strand renaturation (GO:0000733) | 3.00271529 |
| 95 | deoxyribonucleotide biosynthetic process (GO:0009263) | 2.99744789 |
| 96 | IMP biosynthetic process (GO:0006188) | 2.97984351 |
| 97 | regulation of DNA endoreduplication (GO:0032875) | 2.97186262 |
| 98 | pseudouridine synthesis (GO:0001522) | 2.96993188 |
| 99 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.95286647 |
| 100 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.95223222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.74687120 |
| 2 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.81066721 |
| 3 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.72205946 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.92726806 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.92590190 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.85071833 |
| 7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.75199874 |
| 8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.43454514 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.39881689 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.10068624 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.90063008 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.89130309 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.79953429 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.78042603 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.62373027 |
| 16 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.61511958 |
| 17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.54702148 |
| 18 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.48314500 |
| 19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.45704306 |
| 20 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.42854986 |
| 21 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.36797536 |
| 22 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.35745923 |
| 23 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.29760671 |
| 24 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.29055949 |
| 25 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.22805784 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.18379495 |
| 27 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.05443702 |
| 28 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.94774902 |
| 29 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.92274549 |
| 30 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.91838783 |
| 31 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.90712205 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.89917691 |
| 33 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.88762616 |
| 34 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.87823555 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.77107595 |
| 36 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.75375778 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.74384147 |
| 38 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.73582560 |
| 39 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.72597142 |
| 40 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.69625547 |
| 41 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.64429295 |
| 42 | EWS_26573619_Chip-Seq_HEK293_Human | 1.62148169 |
| 43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.61299986 |
| 44 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.57577080 |
| 45 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.55071808 |
| 46 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.53487634 |
| 47 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.50386818 |
| 48 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.47360872 |
| 49 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.44934962 |
| 50 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.44723762 |
| 51 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.44090232 |
| 52 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.41029004 |
| 53 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.37079087 |
| 54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.33939518 |
| 55 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.30274689 |
| 56 | VDR_22108803_ChIP-Seq_LS180_Human | 1.27548622 |
| 57 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.23163892 |
| 58 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.21915671 |
| 59 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.21781849 |
| 60 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.20957494 |
| 61 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.18384508 |
| 62 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.16827485 |
| 63 | * POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.16715368 |
| 64 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.14409072 |
| 65 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.14210908 |
| 66 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.11403751 |
| 67 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.11151318 |
| 68 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.07747200 |
| 69 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.01811385 |
| 70 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.93515037 |
| 71 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.93410256 |
| 72 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.91759632 |
| 73 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.90512341 |
| 74 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.84734491 |
| 75 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.84730233 |
| 76 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.83934100 |
| 77 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.82543747 |
| 78 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.81960344 |
| 79 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.79350051 |
| 80 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.79020824 |
| 81 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.77112422 |
| 82 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.73489510 |
| 83 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.72725411 |
| 84 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.72517781 |
| 85 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.72293327 |
| 86 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.70848515 |
| 87 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.70752539 |
| 88 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.69842405 |
| 89 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.69137728 |
| 90 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.68716251 |
| 91 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.68173416 |
| 92 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.67397612 |
| 93 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.65752499 |
| 94 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.63898578 |
| 95 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.59742262 |
| 96 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.59454362 |
| 97 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.58609842 |
| 98 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.58148178 |
| 99 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.58148178 |
| 100 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.58087649 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 5.13934979 |
| 2 | MP0008058_abnormal_DNA_repair | 4.02168974 |
| 3 | MP0003693_abnormal_embryo_hatching | 3.99896640 |
| 4 | MP0003111_abnormal_nucleus_morphology | 3.64640966 |
| 5 | MP0004957_abnormal_blastocyst_morpholog | 3.50506273 |
| 6 | MP0009379_abnormal_foot_pigmentation | 3.46089975 |
| 7 | MP0008057_abnormal_DNA_replication | 3.33191643 |
| 8 | MP0003077_abnormal_cell_cycle | 3.13926618 |
| 9 | MP0006292_abnormal_olfactory_placode | 2.92496492 |
| 10 | MP0008932_abnormal_embryonic_tissue | 2.57729303 |
| 11 | MP0002938_white_spotting | 2.49460453 |
| 12 | MP0003136_yellow_coat_color | 2.38360143 |
| 13 | MP0008007_abnormal_cellular_replicative | 2.32887813 |
| 14 | MP0003718_maternal_effect | 2.27921381 |
| 15 | MP0009697_abnormal_copulation | 2.27409630 |
| 16 | MP0003806_abnormal_nucleotide_metabolis | 2.11921065 |
| 17 | MP0001293_anophthalmia | 2.04977440 |
| 18 | MP0010030_abnormal_orbit_morphology | 2.01356805 |
| 19 | MP0003786_premature_aging | 1.90826280 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.85653020 |
| 21 | MP0008877_abnormal_DNA_methylation | 1.83843409 |
| 22 | MP0000372_irregular_coat_pigmentation | 1.70120302 |
| 23 | MP0001529_abnormal_vocalization | 1.64392630 |
| 24 | MP0003890_abnormal_embryonic-extraembry | 1.54794713 |
| 25 | MP0003941_abnormal_skin_development | 1.45718528 |
| 26 | MP0003937_abnormal_limbs/digits/tail_de | 1.45034241 |
| 27 | MP0004147_increased_porphyrin_level | 1.42872005 |
| 28 | MP0002102_abnormal_ear_morphology | 1.41677729 |
| 29 | MP0003186_abnormal_redox_activity | 1.40294409 |
| 30 | MP0002210_abnormal_sex_determination | 1.36637815 |
| 31 | MP0002160_abnormal_reproductive_system | 1.34907053 |
| 32 | MP0000350_abnormal_cell_proliferation | 1.34802332 |
| 33 | MP0006035_abnormal_mitochondrial_morpho | 1.33702840 |
| 34 | MP0002234_abnormal_pharynx_morphology | 1.29760939 |
| 35 | MP0006036_abnormal_mitochondrial_physio | 1.25880970 |
| 36 | MP0001286_abnormal_eye_development | 1.23088372 |
| 37 | MP0001697_abnormal_embryo_size | 1.21064671 |
| 38 | MP0001929_abnormal_gametogenesis | 1.18489403 |
| 39 | MP0008995_early_reproductive_senescence | 1.13558640 |
| 40 | MP0008789_abnormal_olfactory_epithelium | 1.12577793 |
| 41 | MP0005084_abnormal_gallbladder_morpholo | 1.11895295 |
| 42 | MP0000049_abnormal_middle_ear | 1.10903606 |
| 43 | MP0001145_abnormal_male_reproductive | 1.10122971 |
| 44 | MP0003567_abnormal_fetal_cardiomyocyte | 1.09457981 |
| 45 | MP0003315_abnormal_perineum_morphology | 1.08832388 |
| 46 | MP0002736_abnormal_nociception_after | 1.08771452 |
| 47 | MP0002085_abnormal_embryonic_tissue | 1.06444104 |
| 48 | MP0005389_reproductive_system_phenotype | 1.06441535 |
| 49 | MP0000631_abnormal_neuroendocrine_gland | 1.06134047 |
| 50 | MP0000653_abnormal_sex_gland | 1.05708862 |
| 51 | MP0000566_synostosis | 1.04766416 |
| 52 | MP0001485_abnormal_pinna_reflex | 1.04124777 |
| 53 | MP0010307_abnormal_tumor_latency | 1.04080731 |
| 54 | MP0003119_abnormal_digestive_system | 1.03828137 |
| 55 | MP0005253_abnormal_eye_physiology | 1.03687582 |
| 56 | MP0002697_abnormal_eye_size | 1.01095180 |
| 57 | MP0005380_embryogenesis_phenotype | 0.98389944 |
| 58 | MP0001672_abnormal_embryogenesis/_devel | 0.98389944 |
| 59 | MP0003121_genomic_imprinting | 0.97001024 |
| 60 | MP0002111_abnormal_tail_morphology | 0.95322813 |
| 61 | MP0002095_abnormal_skin_pigmentation | 0.94400398 |
| 62 | MP0000313_abnormal_cell_death | 0.94222863 |
| 63 | MP0001730_embryonic_growth_arrest | 0.94201198 |
| 64 | MP0001346_abnormal_lacrimal_gland | 0.93687398 |
| 65 | MP0002638_abnormal_pupillary_reflex | 0.90415602 |
| 66 | MP0004133_heterotaxia | 0.90097027 |
| 67 | MP0002084_abnormal_developmental_patter | 0.89429464 |
| 68 | MP0002837_dystrophic_cardiac_calcinosis | 0.88745185 |
| 69 | MP0005408_hypopigmentation | 0.88567462 |
| 70 | MP0001119_abnormal_female_reproductive | 0.87877640 |
| 71 | MP0005391_vision/eye_phenotype | 0.87438252 |
| 72 | MP0003698_abnormal_male_reproductive | 0.84943540 |
| 73 | MP0002751_abnormal_autonomic_nervous | 0.84026846 |
| 74 | MP0002396_abnormal_hematopoietic_system | 0.82999031 |
| 75 | MP0005551_abnormal_eye_electrophysiolog | 0.82588503 |
| 76 | MP0008872_abnormal_physiological_respon | 0.82452952 |
| 77 | MP0002233_abnormal_nose_morphology | 0.82159840 |
| 78 | MP0002080_prenatal_lethality | 0.81643171 |
| 79 | MP0009672_abnormal_birth_weight | 0.80330263 |
| 80 | MP0001764_abnormal_homeostasis | 0.80051936 |
| 81 | MP0000358_abnormal_cell_content/ | 0.79950508 |
| 82 | MP0003011_delayed_dark_adaptation | 0.78593821 |
| 83 | MP0001919_abnormal_reproductive_system | 0.78088632 |
| 84 | MP0003984_embryonic_growth_retardation | 0.77778523 |
| 85 | MP0004142_abnormal_muscle_tone | 0.77208927 |
| 86 | MP0002088_abnormal_embryonic_growth/wei | 0.76201006 |
| 87 | MP0000647_abnormal_sebaceous_gland | 0.76121177 |
| 88 | MP0003123_paternal_imprinting | 0.75154990 |
| 89 | MP0005171_absent_coat_pigmentation | 0.74880221 |
| 90 | MP0002653_abnormal_ependyma_morphology | 0.74843023 |
| 91 | MP0002019_abnormal_tumor_incidence | 0.72612219 |
| 92 | MP0003195_calcinosis | 0.72584397 |
| 93 | MP0005075_abnormal_melanosome_morpholog | 0.70852829 |
| 94 | MP0004197_abnormal_fetal_growth/weight/ | 0.70312271 |
| 95 | MP0003938_abnormal_ear_development | 0.69607980 |
| 96 | MP0002282_abnormal_trachea_morphology | 0.68985018 |
| 97 | MP0003755_abnormal_palate_morphology | 0.67249417 |
| 98 | MP0005195_abnormal_posterior_eye | 0.65689882 |
| 99 | MP0008875_abnormal_xenobiotic_pharmacok | 0.64819080 |
| 100 | MP0000427_abnormal_hair_cycle | 0.64769232 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.11537030 |
| 2 | Chromsome breakage (HP:0040012) | 4.76352640 |
| 3 | Reticulocytopenia (HP:0001896) | 4.50128566 |
| 4 | Meckel diverticulum (HP:0002245) | 4.19434574 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.17858573 |
| 6 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 4.09706123 |
| 7 | Abnormality of the ileum (HP:0001549) | 4.00270891 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.75263525 |
| 9 | Acute encephalopathy (HP:0006846) | 3.74160265 |
| 10 | Abnormality of chromosome stability (HP:0003220) | 3.69902919 |
| 11 | Birth length less than 3rd percentile (HP:0003561) | 3.68273066 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.67977103 |
| 13 | Abnormality of the preputium (HP:0100587) | 3.62270105 |
| 14 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.59970920 |
| 15 | Abnormal number of erythroid precursors (HP:0012131) | 3.59018229 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 3.56435727 |
| 17 | Colon cancer (HP:0003003) | 3.43781051 |
| 18 | Increased CSF lactate (HP:0002490) | 3.40806950 |
| 19 | Progressive macrocephaly (HP:0004481) | 3.35171263 |
| 20 | Macrocytic anemia (HP:0001972) | 3.26395538 |
| 21 | Lipid accumulation in hepatocytes (HP:0006561) | 3.23852517 |
| 22 | Hepatocellular necrosis (HP:0001404) | 3.12883025 |
| 23 | Small intestinal stenosis (HP:0012848) | 3.05025346 |
| 24 | Duodenal stenosis (HP:0100867) | 3.05025346 |
| 25 | Hepatic necrosis (HP:0002605) | 2.86271525 |
| 26 | Triphalangeal thumb (HP:0001199) | 2.84933420 |
| 27 | Congenital, generalized hypertrichosis (HP:0004540) | 2.83667324 |
| 28 | Abnormality of the carotid arteries (HP:0005344) | 2.82411861 |
| 29 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.82312457 |
| 30 | Absent thumb (HP:0009777) | 2.80379070 |
| 31 | Cerebral edema (HP:0002181) | 2.79036827 |
| 32 | Abnormality of the labia minora (HP:0012880) | 2.76643813 |
| 33 | Pallor (HP:0000980) | 2.67704299 |
| 34 | Abnormality of the duodenum (HP:0002246) | 2.64784700 |
| 35 | Renal Fanconi syndrome (HP:0001994) | 2.63113451 |
| 36 | Clubbing of toes (HP:0100760) | 2.61449844 |
| 37 | Pancreatic cysts (HP:0001737) | 2.49865899 |
| 38 | Duplicated collecting system (HP:0000081) | 2.39920148 |
| 39 | Increased serum lactate (HP:0002151) | 2.37007777 |
| 40 | Sloping forehead (HP:0000340) | 2.35533125 |
| 41 | Pancreatic fibrosis (HP:0100732) | 2.33751409 |
| 42 | Myelodysplasia (HP:0002863) | 2.31284104 |
| 43 | Abnormality of the renal collecting system (HP:0004742) | 2.27225925 |
| 44 | Ectopic kidney (HP:0000086) | 2.26387246 |
| 45 | 3-Methylglutaconic aciduria (HP:0003535) | 2.21560879 |
| 46 | Lactic acidosis (HP:0003128) | 2.21527608 |
| 47 | Abnormal lung lobation (HP:0002101) | 2.21053734 |
| 48 | Abnormality of alanine metabolism (HP:0010916) | 2.19993888 |
| 49 | Hyperalaninemia (HP:0003348) | 2.19993888 |
| 50 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.19993888 |
| 51 | True hermaphroditism (HP:0010459) | 2.17828340 |
| 52 | Hypoplasia of the pons (HP:0012110) | 2.16574578 |
| 53 | Patellar aplasia (HP:0006443) | 2.14806721 |
| 54 | Molar tooth sign on MRI (HP:0002419) | 2.14304517 |
| 55 | Abnormality of midbrain morphology (HP:0002418) | 2.14304517 |
| 56 | Absent radius (HP:0003974) | 2.14036197 |
| 57 | Pancytopenia (HP:0001876) | 2.13945041 |
| 58 | Exertional dyspnea (HP:0002875) | 2.12994314 |
| 59 | Leukodystrophy (HP:0002415) | 2.11654019 |
| 60 | Absent forearm bone (HP:0003953) | 2.10833894 |
| 61 | Aplasia involving forearm bones (HP:0009822) | 2.10833894 |
| 62 | Abnormality of the pons (HP:0007361) | 2.10005598 |
| 63 | Septo-optic dysplasia (HP:0100842) | 2.09820776 |
| 64 | Increased intramyocellular lipid droplets (HP:0012240) | 2.08888467 |
| 65 | Respiratory failure (HP:0002878) | 2.03853268 |
| 66 | Horseshoe kidney (HP:0000085) | 2.03128180 |
| 67 | Optic disc pallor (HP:0000543) | 2.02884291 |
| 68 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.02199355 |
| 69 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.00574554 |
| 70 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.99863603 |
| 71 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.99863603 |
| 72 | Methylmalonic acidemia (HP:0002912) | 1.97055171 |
| 73 | Short thumb (HP:0009778) | 1.96327007 |
| 74 | Abnormal number of incisors (HP:0011064) | 1.93098545 |
| 75 | Megaloblastic anemia (HP:0001889) | 1.92068434 |
| 76 | Abnormality of methionine metabolism (HP:0010901) | 1.91521873 |
| 77 | Respiratory difficulties (HP:0002880) | 1.90375658 |
| 78 | Abnormality of serum amino acid levels (HP:0003112) | 1.89558667 |
| 79 | Hyperglycinemia (HP:0002154) | 1.88431346 |
| 80 | Exercise intolerance (HP:0003546) | 1.87507578 |
| 81 | Sclerocornea (HP:0000647) | 1.86870881 |
| 82 | Abnormality of DNA repair (HP:0003254) | 1.84287802 |
| 83 | Pendular nystagmus (HP:0012043) | 1.84239655 |
| 84 | Breast hypoplasia (HP:0003187) | 1.81478009 |
| 85 | Hypoplastic pelvis (HP:0008839) | 1.81091994 |
| 86 | Nephronophthisis (HP:0000090) | 1.80629318 |
| 87 | Methylmalonic aciduria (HP:0012120) | 1.77221910 |
| 88 | Abnormality of cochlea (HP:0000375) | 1.75674172 |
| 89 | Type I transferrin isoform profile (HP:0003642) | 1.75625173 |
| 90 | Duplication of thumb phalanx (HP:0009942) | 1.75558577 |
| 91 | Cleft eyelid (HP:0000625) | 1.75362830 |
| 92 | Lethargy (HP:0001254) | 1.74903033 |
| 93 | Tracheoesophageal fistula (HP:0002575) | 1.73838430 |
| 94 | Small hand (HP:0200055) | 1.72635401 |
| 95 | Absent septum pellucidum (HP:0001331) | 1.70436703 |
| 96 | Volvulus (HP:0002580) | 1.70113864 |
| 97 | Aplastic anemia (HP:0001915) | 1.68379843 |
| 98 | Abnormality of renal resorption (HP:0011038) | 1.67830310 |
| 99 | Microvesicular hepatic steatosis (HP:0001414) | 1.67060029 |
| 100 | Bone marrow hypocellularity (HP:0005528) | 1.65131014 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDC7 | 4.72464931 |
| 2 | VRK2 | 4.36255729 |
| 3 | BUB1 | 4.01963021 |
| 4 | ZAK | 3.70296168 |
| 5 | WEE1 | 3.10267359 |
| 6 | PLK4 | 2.94555917 |
| 7 | TTK | 2.72080273 |
| 8 | SRPK1 | 2.65436886 |
| 9 | VRK1 | 2.61570239 |
| 10 | NEK1 | 2.41357335 |
| 11 | BRSK2 | 2.24638080 |
| 12 | STK16 | 2.21005711 |
| 13 | PLK3 | 2.20913365 |
| 14 | PBK | 2.16491685 |
| 15 | TAF1 | 2.08007874 |
| 16 | NUAK1 | 1.94948384 |
| 17 | NME1 | 1.91632434 |
| 18 | MKNK1 | 1.91307278 |
| 19 | TLK1 | 1.85489942 |
| 20 | BMPR1B | 1.83816284 |
| 21 | EIF2AK1 | 1.82135690 |
| 22 | PLK1 | 1.80803171 |
| 23 | MKNK2 | 1.77475442 |
| 24 | MST4 | 1.61505490 |
| 25 | CHEK2 | 1.60256841 |
| 26 | EIF2AK3 | 1.49960073 |
| 27 | TRIM28 | 1.48182428 |
| 28 | WNK3 | 1.48006849 |
| 29 | ATR | 1.47253108 |
| 30 | NEK2 | 1.35778016 |
| 31 | TSSK6 | 1.32849032 |
| 32 | AURKB | 1.32820872 |
| 33 | BRSK1 | 1.28849385 |
| 34 | CCNB1 | 1.26137143 |
| 35 | NME2 | 1.24241374 |
| 36 | TNIK | 1.21148488 |
| 37 | PASK | 1.17391529 |
| 38 | ACVR1B | 1.10548350 |
| 39 | DYRK2 | 1.03769877 |
| 40 | PNCK | 1.02168920 |
| 41 | CDK8 | 0.98078095 |
| 42 | EIF2AK2 | 0.96915209 |
| 43 | CDK7 | 0.91018287 |
| 44 | WNK4 | 0.89752157 |
| 45 | MAP4K2 | 0.89348655 |
| 46 | ADRBK2 | 0.87108877 |
| 47 | DYRK3 | 0.86331447 |
| 48 | TGFBR1 | 0.83767607 |
| 49 | GRK1 | 0.80779112 |
| 50 | AURKA | 0.80603455 |
| 51 | INSRR | 0.76278738 |
| 52 | ATM | 0.75694386 |
| 53 | CHEK1 | 0.74873001 |
| 54 | BCKDK | 0.71380975 |
| 55 | FRK | 0.66907933 |
| 56 | CSNK2A1 | 0.66901040 |
| 57 | STK4 | 0.65516547 |
| 58 | CSNK1G1 | 0.60786453 |
| 59 | CSNK2A2 | 0.60458475 |
| 60 | CSNK1G3 | 0.60433345 |
| 61 | PLK2 | 0.59702497 |
| 62 | RPS6KA5 | 0.57104067 |
| 63 | RPS6KA4 | 0.56147822 |
| 64 | RPS6KB2 | 0.53630052 |
| 65 | STK38L | 0.53492582 |
| 66 | STK3 | 0.50790232 |
| 67 | MAPKAPK5 | 0.50771942 |
| 68 | MELK | 0.50584812 |
| 69 | CDK1 | 0.50184975 |
| 70 | CSNK1G2 | 0.49842151 |
| 71 | CDK3 | 0.48465828 |
| 72 | OXSR1 | 0.46887266 |
| 73 | PDK2 | 0.46548655 |
| 74 | CDK2 | 0.42687638 |
| 75 | STK39 | 0.42618664 |
| 76 | CSNK1A1L | 0.39372488 |
| 77 | BCR | 0.38935882 |
| 78 | CSNK1E | 0.37404445 |
| 79 | CDK19 | 0.34973127 |
| 80 | CDK4 | 0.34845547 |
| 81 | PRKCG | 0.31034160 |
| 82 | PRKDC | 0.30985316 |
| 83 | ALK | 0.29865940 |
| 84 | MAP3K4 | 0.29490200 |
| 85 | MARK3 | 0.29347971 |
| 86 | ERBB3 | 0.27657454 |
| 87 | ADRBK1 | 0.26925205 |
| 88 | MAP3K8 | 0.24476217 |
| 89 | CSNK1A1 | 0.23325886 |
| 90 | PRKCI | 0.23291910 |
| 91 | MUSK | 0.23036683 |
| 92 | DAPK1 | 0.22313996 |
| 93 | CDK11A | 0.19920837 |
| 94 | CDK18 | 0.19680619 |
| 95 | MAP2K7 | 0.19579804 |
| 96 | MAPK13 | 0.19356960 |
| 97 | FGFR1 | 0.18521691 |
| 98 | CDK15 | 0.18499392 |
| 99 | EPHB2 | 0.17648238 |
| 100 | FLT3 | 0.17426991 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 4.56632865 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 4.20820122 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 4.09415077 |
| 4 | Homologous recombination_Homo sapiens_hsa03440 | 3.63715376 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.43724031 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.17123622 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.86224961 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.80176297 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.73098184 |
| 10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.62290099 |
| 11 | Base excision repair_Homo sapiens_hsa03410 | 2.55702294 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.51167906 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.39465800 |
| 14 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.33089515 |
| 15 | Spliceosome_Homo sapiens_hsa03040 | 2.26839085 |
| 16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.22010131 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 2.09842396 |
| 18 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.95788669 |
| 19 | Cell cycle_Homo sapiens_hsa04110 | 1.88576930 |
| 20 | RNA transport_Homo sapiens_hsa03013 | 1.84736892 |
| 21 | Alzheimers disease_Homo sapiens_hsa05010 | 1.78310722 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.73523865 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.61926980 |
| 24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.51640859 |
| 25 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.44617886 |
| 26 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38060071 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.37127024 |
| 28 | Purine metabolism_Homo sapiens_hsa00230 | 1.34663330 |
| 29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.17490162 |
| 30 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.16311481 |
| 31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.13571869 |
| 32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.12871297 |
| 33 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.11885695 |
| 34 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.10973740 |
| 35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.05999138 |
| 36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04574735 |
| 37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.96072111 |
| 38 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.90400639 |
| 39 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.86000457 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.82174517 |
| 41 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.82054649 |
| 42 | Sulfur relay system_Homo sapiens_hsa04122 | 0.81029122 |
| 43 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.78692199 |
| 44 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.77032118 |
| 45 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.73247140 |
| 46 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.71697930 |
| 47 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.70919607 |
| 48 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.70826845 |
| 49 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.68422800 |
| 50 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68017966 |
| 51 | Phototransduction_Homo sapiens_hsa04744 | 0.66709050 |
| 52 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65368485 |
| 53 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.63757193 |
| 54 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.61503323 |
| 55 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.60080942 |
| 56 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.57056262 |
| 57 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.56458050 |
| 58 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.53403727 |
| 59 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.52128244 |
| 60 | Carbon metabolism_Homo sapiens_hsa01200 | 0.51683915 |
| 61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.51070239 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.47688361 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.46873516 |
| 64 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.45105331 |
| 65 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.44898572 |
| 66 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.43831115 |
| 67 | Peroxisome_Homo sapiens_hsa04146 | 0.43278761 |
| 68 | Alcoholism_Homo sapiens_hsa05034 | 0.37318954 |
| 69 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.36650435 |
| 70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.36296832 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.33930047 |
| 72 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.33772388 |
| 73 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.33697555 |
| 74 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.32830253 |
| 75 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.32565041 |
| 76 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.32475422 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.30832304 |
| 78 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.29310851 |
| 79 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.27406304 |
| 80 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.26801336 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.26303407 |
| 82 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.25729301 |
| 83 | Retinol metabolism_Homo sapiens_hsa00830 | 0.24058624 |
| 84 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.23709447 |
| 85 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.23251895 |
| 86 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.22402915 |
| 87 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.20422359 |
| 88 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.20374902 |
| 89 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.19768691 |
| 90 | Olfactory transduction_Homo sapiens_hsa04740 | 0.19592436 |
| 91 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.17392393 |
| 92 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.17217267 |
| 93 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.16736179 |
| 94 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.15575091 |
| 95 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.14909490 |
| 96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.14249498 |
| 97 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.13968684 |
| 98 | Lysine degradation_Homo sapiens_hsa00310 | 0.13475962 |
| 99 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.12949886 |
| 100 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.11856456 |

