KIAA0825

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cilium or flagellum-dependent cell motility (GO:0001539)9.33836846
2epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.15526068
3cilium movement (GO:0003341)6.74961278
4axoneme assembly (GO:0035082)6.57880437
5retinal cone cell development (GO:0046549)6.35233646
6epithelial cilium movement (GO:0003351)6.01212140
7axonemal dynein complex assembly (GO:0070286)5.61615332
8retinal rod cell development (GO:0046548)5.41681747
9protein K11-linked deubiquitination (GO:0035871)4.95917865
10motile cilium assembly (GO:0044458)4.73082984
11neural tube formation (GO:0001841)4.51021853
12photoreceptor cell maintenance (GO:0045494)4.48780284
13regulation of cilium movement (GO:0003352)4.39397738
14establishment of protein localization to Golgi (GO:0072600)4.32953497
15indolalkylamine metabolic process (GO:0006586)3.90828269
16indole-containing compound catabolic process (GO:0042436)3.86675651
17indolalkylamine catabolic process (GO:0046218)3.86675651
18tryptophan catabolic process (GO:0006569)3.86675651
19ventricular system development (GO:0021591)3.76675752
20cilium organization (GO:0044782)3.69072108
21protein targeting to Golgi (GO:0000042)3.67817267
22response to pheromone (GO:0019236)3.62900190
23tryptophan metabolic process (GO:0006568)3.59384490
24cilium assembly (GO:0042384)3.41824617
25fucose catabolic process (GO:0019317)3.39870156
26L-fucose metabolic process (GO:0042354)3.39870156
27L-fucose catabolic process (GO:0042355)3.39870156
28retrograde transport, vesicle recycling within Golgi (GO:0000301)3.35200656
29detection of light stimulus involved in sensory perception (GO:0050962)3.32379405
30detection of light stimulus involved in visual perception (GO:0050908)3.32379405
31cilium morphogenesis (GO:0060271)3.30895183
32protein polyglutamylation (GO:0018095)3.23456318
33photoreceptor cell development (GO:0042461)3.20430147
34prenylation (GO:0097354)3.13572375
35protein prenylation (GO:0018342)3.13572375
36eye photoreceptor cell development (GO:0042462)3.13417773
37interkinetic nuclear migration (GO:0022027)3.09004640
38microtubule bundle formation (GO:0001578)3.05214001
39adaptation of signaling pathway (GO:0023058)3.04175479
40detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.04148201
41regulation of B cell receptor signaling pathway (GO:0050855)3.02360618
42negative regulation of translation, ncRNA-mediated (GO:0040033)3.00775930
43regulation of translation, ncRNA-mediated (GO:0045974)3.00775930
44negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.00775930
45snRNA transcription (GO:0009301)2.97560445
46cellular component assembly involved in morphogenesis (GO:0010927)2.95304025
47left/right axis specification (GO:0070986)2.93483615
48negative regulation of mast cell activation (GO:0033004)2.91022957
49phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.89821216
50cAMP catabolic process (GO:0006198)2.88511006
51protein localization to Golgi apparatus (GO:0034067)2.87791223
52kynurenine metabolic process (GO:0070189)2.85970336
53negative regulation of complement activation (GO:0045916)2.84643075
54intraciliary transport (GO:0042073)2.84198203
55dopamine transport (GO:0015872)2.82226149
56monoubiquitinated protein deubiquitination (GO:0035520)2.78899019
57brain morphogenesis (GO:0048854)2.77913112
58rRNA catabolic process (GO:0016075)2.77748934
59cell wall macromolecule catabolic process (GO:0016998)2.72973405
60negative regulation of cytosolic calcium ion concentration (GO:0051481)2.72134565
61nonmotile primary cilium assembly (GO:0035058)2.72022615
62piRNA metabolic process (GO:0034587)2.71804454
63cyclic nucleotide catabolic process (GO:0009214)2.71613330
64sperm motility (GO:0030317)2.70914504
65indole-containing compound metabolic process (GO:0042430)2.68653576
66histone mRNA catabolic process (GO:0071044)2.66949143
67centriole replication (GO:0007099)2.64750807
68reflex (GO:0060004)2.63737299
69interleukin-6-mediated signaling pathway (GO:0070102)2.61301389
70protein localization to cilium (GO:0061512)2.61262073
71positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.59550813
72oxidative demethylation (GO:0070989)2.57797817
73protein K48-linked deubiquitination (GO:0071108)2.56942052
74microtubule anchoring (GO:0034453)2.52506750
75synapsis (GO:0007129)2.48632974
76negative regulation of protein activation cascade (GO:2000258)2.45231029
77DNA methylation involved in gamete generation (GO:0043046)2.44753575
78protein K63-linked deubiquitination (GO:0070536)2.44335599
79thyroid hormone metabolic process (GO:0042403)2.44135006
80tachykinin receptor signaling pathway (GO:0007217)2.41608110
81ubiquinone biosynthetic process (GO:0006744)2.40208169
82cell wall macromolecule metabolic process (GO:0044036)2.39992359
83interferon-gamma production (GO:0032609)2.39700821
84signal peptide processing (GO:0006465)2.37373014
85sulfation (GO:0051923)2.37018641
86regulation of MHC class II biosynthetic process (GO:0045346)2.36715677
87multicellular organism reproduction (GO:0032504)2.36434423
88phosphorelay signal transduction system (GO:0000160)2.35982143
89NAD biosynthetic process (GO:0009435)2.34454076
90benzene-containing compound metabolic process (GO:0042537)2.33868434
91tyrosine phosphorylation of STAT protein (GO:0007260)2.32023530
92double-strand break repair via homologous recombination (GO:0000724)2.29360750
93cell projection assembly (GO:0030031)2.29317584
94acrosome reaction (GO:0007340)2.28858887
95recombinational repair (GO:0000725)2.28428937
96hepatocyte apoptotic process (GO:0097284)2.27332719
97negative regulation of humoral immune response (GO:0002921)2.27273870
98embryonic epithelial tube formation (GO:0001838)2.25876374
99phospholipid translocation (GO:0045332)2.25841621
100lipid translocation (GO:0034204)2.25841621

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.41987261
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.11445696
3POU3F2_20337985_ChIP-ChIP_501MEL_Human2.80448897
4IGF1R_20145208_ChIP-Seq_DFB_Human2.73912686
5CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.70348650
6ZNF274_21170338_ChIP-Seq_K562_Hela2.58600362
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.55906884
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.54317767
9BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.53693582
10VDR_22108803_ChIP-Seq_LS180_Human2.53102889
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.45225550
12TAF15_26573619_Chip-Seq_HEK293_Human2.33874206
13GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.30032776
14FUS_26573619_Chip-Seq_HEK293_Human2.23735618
15AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.22783308
16SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.14090924
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.11294519
18CTBP2_25329375_ChIP-Seq_LNCAP_Human2.07374181
19P300_19829295_ChIP-Seq_ESCs_Human2.00813965
20SMAD_19615063_ChIP-ChIP_OVARY_Human1.99796643
21PCGF2_27294783_Chip-Seq_ESCs_Mouse1.98404652
22SMAD4_21799915_ChIP-Seq_A2780_Human1.97112578
23ER_23166858_ChIP-Seq_MCF-7_Human1.96307453
24STAT3_23295773_ChIP-Seq_U87_Human1.89202004
25EWS_26573619_Chip-Seq_HEK293_Human1.86562787
26AR_21572438_ChIP-Seq_LNCaP_Human1.85256502
27PIAS1_25552417_ChIP-Seq_VCAP_Human1.84104803
28CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81486615
29PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.77289850
30IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.69052477
31CBP_20019798_ChIP-Seq_JUKART_Human1.69052477
32UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.68935652
33SUZ12_27294783_Chip-Seq_NPCs_Mouse1.66973298
34EZH2_27294783_Chip-Seq_NPCs_Mouse1.66668166
35TCF4_23295773_ChIP-Seq_U87_Human1.63823772
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.60269186
37NFE2_27457419_Chip-Seq_LIVER_Mouse1.59080861
38MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.54392050
39BCAT_22108803_ChIP-Seq_LS180_Human1.53140093
40NR3C1_21868756_ChIP-Seq_MCF10A_Human1.48141117
41SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.45285101
42SMAD3_21741376_ChIP-Seq_EPCs_Human1.45122055
43AR_25329375_ChIP-Seq_VCAP_Human1.44395574
44SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43327133
45TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42700709
46PCGF2_27294783_Chip-Seq_NPCs_Mouse1.41091959
47OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40831143
48CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.40432490
49STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.39595015
50FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.38669759
51TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.38187148
52NANOG_18555785_Chip-Seq_ESCs_Mouse1.38079553
53TP53_16413492_ChIP-PET_HCT116_Human1.36981154
54TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.33926509
55TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32688172
56POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.32688172
57CRX_20693478_ChIP-Seq_RETINA_Mouse1.31572039
58TCF4_22108803_ChIP-Seq_LS180_Human1.30238066
59EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.29950106
60FOXM1_26456572_ChIP-Seq_MCF-7_Human1.29418414
61RUNX2_22187159_ChIP-Seq_PCA_Human1.29061558
62FLI1_21867929_ChIP-Seq_TH2_Mouse1.28913669
63PRDM14_20953172_ChIP-Seq_ESCs_Human1.28181974
64TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26308710
65KLF5_20875108_ChIP-Seq_MESCs_Mouse1.25398922
66NANOG_19829295_ChIP-Seq_ESCs_Human1.24163548
67SOX2_19829295_ChIP-Seq_ESCs_Human1.24163548
68TP53_22573176_ChIP-Seq_HFKS_Human1.23924055
69ARNT_22903824_ChIP-Seq_MCF-7_Human1.23124757
70CDX2_19796622_ChIP-Seq_MESCs_Mouse1.23080622
71P53_22387025_ChIP-Seq_ESCs_Mouse1.22895672
72OCT4_21477851_ChIP-Seq_ESCs_Mouse1.21820045
73ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.21298520
74E2F1_18555785_Chip-Seq_ESCs_Mouse1.20511168
75RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19188536
76CDX2_22108803_ChIP-Seq_LS180_Human1.18393058
77AHR_22903824_ChIP-Seq_MCF-7_Human1.18027080
78EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.15718703
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14437348
80SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.13778250
81FOXA1_21572438_ChIP-Seq_LNCaP_Human1.13593043
82MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.13555116
83SMAD4_21741376_ChIP-Seq_EPCs_Human1.13550739
84IRF8_22096565_ChIP-ChIP_GC-B_Human1.12239025
85SUZ12_18555785_Chip-Seq_ESCs_Mouse1.11846791
86TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11243070
87CMYC_18555785_Chip-Seq_ESCs_Mouse1.10860923
88EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.07858942
89STAT3_18555785_Chip-Seq_ESCs_Mouse1.07547061
90ZNF217_24962896_ChIP-Seq_MCF-7_Human1.06200074
91P300_18555785_Chip-Seq_ESCs_Mouse1.05942307
92IRF1_19129219_ChIP-ChIP_H3396_Human1.05610707
93TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.05380191
94CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.05207093
95SOX2_21211035_ChIP-Seq_LN229_Gbm1.03846591
96KDM2B_26808549_Chip-Seq_REH_Human1.03608412
97FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03329636
98EGR1_23403033_ChIP-Seq_LIVER_Mouse1.01227655
99FOXA1_25329375_ChIP-Seq_VCAP_Human0.98887951
100FOXA1_27270436_Chip-Seq_PROSTATE_Human0.98887951

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation5.25118065
2MP0008057_abnormal_DNA_replication3.66307136
3MP0003195_calcinosis3.53032183
4MP0008877_abnormal_DNA_methylation3.48240458
5MP0005551_abnormal_eye_electrophysiolog2.90329019
6MP0005253_abnormal_eye_physiology2.70493970
7MP0000427_abnormal_hair_cycle2.20796155
8MP0000383_abnormal_hair_follicle2.19022267
9MP0001984_abnormal_olfaction2.08288203
10MP0009046_muscle_twitch2.07156099
11MP0006072_abnormal_retinal_apoptosis1.89128657
12MP0003880_abnormal_central_pattern1.85414537
13MP0003646_muscle_fatigue1.77006827
14MP0002653_abnormal_ependyma_morphology1.67926706
15MP0003787_abnormal_imprinting1.67275689
16MP0005310_abnormal_salivary_gland1.64247315
17MP0003724_increased_susceptibility_to1.61478174
18MP0006276_abnormal_autonomic_nervous1.60537891
19MP0010678_abnormal_skin_adnexa1.57568471
20MP0006054_spinal_hemorrhage1.56352249
21MP0004142_abnormal_muscle_tone1.54245748
22MP0001486_abnormal_startle_reflex1.54160265
23MP0004043_abnormal_pH_regulation1.53573985
24MP0001968_abnormal_touch/_nociception1.52392750
25MP0001501_abnormal_sleep_pattern1.51868034
26MP0003045_fibrosis1.45382040
27MP0002102_abnormal_ear_morphology1.41249957
28MP0003183_abnormal_peptide_metabolism1.37437827
29MP0005174_abnormal_tail_pigmentation1.37417907
30MP0000015_abnormal_ear_pigmentation1.34873573
31MP0002876_abnormal_thyroid_physiology1.31772879
32MP0005410_abnormal_fertilization1.30746627
33MP0002736_abnormal_nociception_after1.27829976
34MP0010386_abnormal_urinary_bladder1.27132882
35MP0004484_altered_response_of1.22106574
36MP0002168_other_aberrant_phenotype1.19878898
37MP0009745_abnormal_behavioral_response1.19471785
38MP0003950_abnormal_plasma_membrane1.18975727
39MP0005645_abnormal_hypothalamus_physiol1.17644567
40MP0000372_irregular_coat_pigmentation1.15452967
41MP0005389_reproductive_system_phenotype1.13961840
42MP0001929_abnormal_gametogenesis1.13212690
43MP0002229_neurodegeneration1.11934752
44MP0003698_abnormal_male_reproductive1.11346386
45MP0008995_early_reproductive_senescence1.09855554
46MP0002160_abnormal_reproductive_system1.09751376
47MP0008872_abnormal_physiological_respon1.09014073
48MP0002009_preneoplasia1.08025007
49MP0002272_abnormal_nervous_system1.05443958
50MP0000631_abnormal_neuroendocrine_gland1.05232722
51MP0003656_abnormal_erythrocyte_physiolo1.05184929
52MP0005167_abnormal_blood-brain_barrier1.04135454
53MP0008875_abnormal_xenobiotic_pharmacok1.01376456
54MP0000647_abnormal_sebaceous_gland1.00539917
55MP0001324_abnormal_eye_pigmentation0.99517743
56MP0001970_abnormal_pain_threshold0.96501728
57MP0005395_other_phenotype0.96315489
58MP0004134_abnormal_chest_morphology0.96196671
59MP0009697_abnormal_copulation0.94821788
60MP0005195_abnormal_posterior_eye0.94257006
61MP0004215_abnormal_myocardial_fiber0.93956128
62MP0005386_behavior/neurological_phenoty0.93172347
63MP0004924_abnormal_behavior0.93172347
64MP0003718_maternal_effect0.91574677
65MP0001986_abnormal_taste_sensitivity0.91346722
66MP0002572_abnormal_emotion/affect_behav0.88127967
67MP0000230_abnormal_systemic_arterial0.86742112
68MP0002067_abnormal_sensory_capabilities0.86367702
69MP0005379_endocrine/exocrine_gland_phen0.86249899
70MP0002735_abnormal_chemical_nociception0.85684953
71MP0006082_CNS_inflammation0.84751080
72MP0002928_abnormal_bile_duct0.84111041
73MP0005075_abnormal_melanosome_morpholog0.83140950
74MP0005391_vision/eye_phenotype0.83004573
75MP0002163_abnormal_gland_morphology0.82563124
76MP0002277_abnormal_respiratory_mucosa0.81880198
77MP0002909_abnormal_adrenal_gland0.81833533
78MP0003633_abnormal_nervous_system0.81107583
79MP0001800_abnormal_humoral_immune0.80354238
80MP0005377_hearing/vestibular/ear_phenot0.79888471
81MP0003878_abnormal_ear_physiology0.79888471
82MP0003011_delayed_dark_adaptation0.79840962
83MP0001485_abnormal_pinna_reflex0.77678886
84MP0002557_abnormal_social/conspecific_i0.76944709
85MP0004145_abnormal_muscle_electrophysio0.76544945
86MP0000653_abnormal_sex_gland0.76235702
87MP0005266_abnormal_metabolism0.74746893
88MP0002166_altered_tumor_susceptibility0.71817717
89MP0003252_abnormal_bile_duct0.71071383
90MP0004381_abnormal_hair_follicle0.70542979
91MP0004147_increased_porphyrin_level0.70367292
92MP0005085_abnormal_gallbladder_physiolo0.70053342
93MP0002095_abnormal_skin_pigmentation0.68567664
94MP0005671_abnormal_response_to0.67826720
95MP0000465_gastrointestinal_hemorrhage0.67241696
96MP0001835_abnormal_antigen_presentation0.66987563
97MP0002210_abnormal_sex_determination0.66931600
98MP0003763_abnormal_thymus_physiology0.66511914
99MP0010329_abnormal_lipoprotein_level0.65450555
100MP0001919_abnormal_reproductive_system0.64937977

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)7.23858939
2Absent/shortened dynein arms (HP:0200106)7.23858939
3Abnormal ciliary motility (HP:0012262)5.48549351
4Respiratory insufficiency due to defective ciliary clearance (HP:0200073)5.29537727
5Chronic hepatic failure (HP:0100626)5.10647501
6Absent rod-and cone-mediated responses on ERG (HP:0007688)4.95827180
7Abnormal respiratory motile cilium physiology (HP:0012261)4.84833561
8Abnormal respiratory epithelium morphology (HP:0012253)4.73535656
9Abnormal respiratory motile cilium morphology (HP:0005938)4.73535656
10Tubulointerstitial nephritis (HP:0001970)3.97500575
11Abnormal rod and cone electroretinograms (HP:0008323)3.96107669
12Pancreatic cysts (HP:0001737)3.87013332
13Pancreatic fibrosis (HP:0100732)3.71612759
14True hermaphroditism (HP:0010459)3.68581579
15Molar tooth sign on MRI (HP:0002419)3.67331528
16Abnormality of midbrain morphology (HP:0002418)3.67331528
17Rhinitis (HP:0012384)3.55705582
18Nephronophthisis (HP:0000090)3.50992600
19Bony spicule pigmentary retinopathy (HP:0007737)3.34848905
20Medial flaring of the eyebrow (HP:0010747)3.21657452
21Chronic bronchitis (HP:0004469)3.11596258
22Abnormality of the renal medulla (HP:0100957)3.10232629
23Bronchiectasis (HP:0002110)3.09773579
24Constricted visual fields (HP:0001133)2.95196897
25Cerebellar dysplasia (HP:0007033)2.94215701
26Gaze-evoked nystagmus (HP:0000640)2.90995075
27Abnormality of the renal cortex (HP:0011035)2.84808378
28Attenuation of retinal blood vessels (HP:0007843)2.77038861
29Congenital primary aphakia (HP:0007707)2.74340859
30Gait imbalance (HP:0002141)2.67615457
31Type II lissencephaly (HP:0007260)2.53534403
32Nephrogenic diabetes insipidus (HP:0009806)2.45084204
33Bronchitis (HP:0012387)2.42048912
34Tubular atrophy (HP:0000092)2.39059263
35Occipital encephalocele (HP:0002085)2.37057988
36Genetic anticipation (HP:0003743)2.33467629
37Cystic liver disease (HP:0006706)2.32022898
38Hyperventilation (HP:0002883)2.30933055
39Polydipsia (HP:0001959)2.30037210
40Abnormal drinking behavior (HP:0030082)2.30037210
41Febrile seizures (HP:0002373)2.27767917
42Poor coordination (HP:0002370)2.24723213
43Genital tract atresia (HP:0001827)2.20827739
44Aplasia/Hypoplasia of the tibia (HP:0005772)2.18436930
45Aplasia/Hypoplasia of the tongue (HP:0010295)2.14879818
46Congenital stationary night blindness (HP:0007642)2.14588726
47Cone-rod dystrophy (HP:0000548)2.14457494
48Decreased circulating renin level (HP:0003351)2.11870883
49Progressive cerebellar ataxia (HP:0002073)2.10227461
50Tubulointerstitial abnormality (HP:0001969)2.08190155
51Vaginal atresia (HP:0000148)2.07583058
52Absent speech (HP:0001344)2.04376315
53Congenital hepatic fibrosis (HP:0002612)2.03843216
54Abolished electroretinogram (ERG) (HP:0000550)2.02899064
55Stomatitis (HP:0010280)1.99200201
56Recurrent sinusitis (HP:0011108)1.98395287
57Decreased central vision (HP:0007663)1.97325312
58Renal cortical cysts (HP:0000803)1.96096711
59Postaxial foot polydactyly (HP:0001830)1.94754076
60Stomach cancer (HP:0012126)1.94659255
61Recurrent bronchitis (HP:0002837)1.94235113
62Male pseudohermaphroditism (HP:0000037)1.90555029
63Fair hair (HP:0002286)1.90075716
64Abnormality of macular pigmentation (HP:0008002)1.87876842
65Lissencephaly (HP:0001339)1.86720864
66Partial agenesis of the corpus callosum (HP:0001338)1.85792359
67Widely spaced teeth (HP:0000687)1.84591290
68Progressive inability to walk (HP:0002505)1.84234886
69Hypothermia (HP:0002045)1.83312306
70Anencephaly (HP:0002323)1.80067399
71Retinitis pigmentosa (HP:0000510)1.78883562
72Furrowed tongue (HP:0000221)1.78073116
73Metaphyseal dysplasia (HP:0100255)1.77858348
74Protruding tongue (HP:0010808)1.76306267
75Menstrual irregularities (HP:0000858)1.75470852
76Inability to walk (HP:0002540)1.74698233
77Bile duct proliferation (HP:0001408)1.73753674
78Abnormal biliary tract physiology (HP:0012439)1.73753674
79Postaxial hand polydactyly (HP:0001162)1.73337361
80Astigmatism (HP:0000483)1.71859575
81Portal hypertension (HP:0001409)1.71306752
82Thyroiditis (HP:0100646)1.69634359
83Large for gestational age (HP:0001520)1.67521488
84Hyperkalemia (HP:0002153)1.66363899
85Nasal polyposis (HP:0100582)1.62985636
86Polyuria (HP:0000103)1.62684129
87Prominent nasal bridge (HP:0000426)1.61429536
88Facial diplegia (HP:0001349)1.60907799
89Hypokalemic alkalosis (HP:0001949)1.58415064
90Chronic sinusitis (HP:0011109)1.58367915
91Congenital sensorineural hearing impairment (HP:0008527)1.56861758
92Oculomotor apraxia (HP:0000657)1.55947003
93Macular degeneration (HP:0000608)1.55611497
94Growth hormone deficiency (HP:0000824)1.55443979
95Short foot (HP:0001773)1.53559219
96Photophobia (HP:0000613)1.53339590
97Generalized hypopigmentation of hair (HP:0011358)1.52742565
98Truncal obesity (HP:0001956)1.50229040
99Abnormality of the hepatic vasculature (HP:0006707)1.48700661
100Hip dysplasia (HP:0001385)1.46852119

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK7.53853532
2MAP4K22.83492856
3WNK32.45021162
4TAOK32.31819417
5MST42.21233624
6ACVR1B2.03509527
7BMPR1B2.01361577
8STK38L1.87861688
9IRAK11.84424240
10NUAK11.81969985
11ADRBK21.78784903
12OXSR11.69639752
13MAP3K41.62559429
14STK391.62404132
15TEC1.59497061
16AKT31.58279404
17PINK11.56583724
18PIK3CG1.55098509
19INSRR1.49317210
20PAK31.45004118
21MAPK131.44811013
22ZAK1.40662621
23FER1.35755223
24TXK1.35415396
25GRK11.32744616
26WNK41.30012489
27BRSK21.20895182
28PDK21.18245911
29CAMKK21.18106422
30PTK2B1.08828270
31ERBB31.08364964
32SGK21.07888120
33TRIM281.07438707
34BLK1.01295077
35PLK20.98949949
36BCR0.93789276
37BRD40.86319409
38TNK20.84415031
39PRKCE0.84166113
40CASK0.80710838
41ADRBK10.80390524
42ITK0.80120565
43MAP2K70.79689042
44LATS10.79562981
45WNK10.78830005
46TNIK0.71120571
47STK30.70938112
48NLK0.69576311
49EIF2AK30.68777662
50EPHA30.66075138
51TYK20.65567867
52PIK3CA0.65483309
53STK380.64404590
54FGFR20.64384477
55BTK0.63849924
56STK110.62620873
57CSNK1A1L0.62346560
58MAPK150.59524303
59YES10.58750445
60IKBKB0.56970855
61TRPM70.56920998
62MAP2K40.56740946
63PLK40.56672795
64ERBB20.56226815
65NTRK30.55811684
66IKBKE0.55284562
67MAP3K20.55225036
68MAP3K70.54655458
69NEK60.52572692
70MUSK0.51310832
71MKNK20.50712199
72CAMK2A0.50400264
73CSNK1G10.49182907
74GRK50.48883394
75DAPK20.48801881
76PRKAA20.47899760
77GRK70.46994928
78JAK10.46916829
79PRKCQ0.45831295
80SGK2230.45494961
81SGK4940.45494961
82KIT0.44861204
83SRPK10.44706471
84HCK0.43177045
85CSNK1G20.41703769
86RPS6KA50.41672498
87CAMK1G0.39842404
88TGFBR10.39280342
89FES0.37817714
90ATM0.37794244
91IRAK40.37757025
92LYN0.37516191
93PRKG10.37408552
94ABL10.36696856
95SGK30.35919528
96MKNK10.35723418
97CAMK40.35683307
98BMPR20.35264781
99PRKAA10.35082886
100SYK0.34805497

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.76601288
2Nitrogen metabolism_Homo sapiens_hsa009102.58056007
3Neuroactive ligand-receptor interaction_Homo sapiens_hsa040802.17103380
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.16248013
5Nicotine addiction_Homo sapiens_hsa050332.15988567
6ABC transporters_Homo sapiens_hsa020102.11391449
7Butanoate metabolism_Homo sapiens_hsa006502.09120013
8Linoleic acid metabolism_Homo sapiens_hsa005912.06954153
9Dorso-ventral axis formation_Homo sapiens_hsa043202.06559510
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.03723077
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.99394645
12Selenocompound metabolism_Homo sapiens_hsa004501.86169556
13Phototransduction_Homo sapiens_hsa047441.85219612
14Basal transcription factors_Homo sapiens_hsa030221.84943200
15Circadian rhythm_Homo sapiens_hsa047101.75534139
16Fanconi anemia pathway_Homo sapiens_hsa034601.73734041
17Taste transduction_Homo sapiens_hsa047421.72319714
18Tryptophan metabolism_Homo sapiens_hsa003801.70378581
19Primary bile acid biosynthesis_Homo sapiens_hsa001201.69194864
20Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.68730777
21Ether lipid metabolism_Homo sapiens_hsa005651.55874285
22Olfactory transduction_Homo sapiens_hsa047401.53784587
23Morphine addiction_Homo sapiens_hsa050321.52735999
24Steroid hormone biosynthesis_Homo sapiens_hsa001401.42025663
25Primary immunodeficiency_Homo sapiens_hsa053401.39637943
26Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.39174211
27Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.32945409
28Non-homologous end-joining_Homo sapiens_hsa034501.31015385
29Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.29430574
30Regulation of autophagy_Homo sapiens_hsa041401.28261335
31Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.26034070
32Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.25808992
33Propanoate metabolism_Homo sapiens_hsa006401.24578531
34Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.23818208
35Homologous recombination_Homo sapiens_hsa034401.23583876
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.18791614
37Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.15867361
38Salivary secretion_Homo sapiens_hsa049701.11850447
39Chemical carcinogenesis_Homo sapiens_hsa052041.09910328
40Retinol metabolism_Homo sapiens_hsa008301.08589300
41GABAergic synapse_Homo sapiens_hsa047271.07845890
42Serotonergic synapse_Homo sapiens_hsa047261.07213056
43Ovarian steroidogenesis_Homo sapiens_hsa049131.06090479
44Glutamatergic synapse_Homo sapiens_hsa047241.03002276
45NOD-like receptor signaling pathway_Homo sapiens_hsa046211.00015632
46Peroxisome_Homo sapiens_hsa041460.97496272
47Calcium signaling pathway_Homo sapiens_hsa040200.97412852
48Hematopoietic cell lineage_Homo sapiens_hsa046400.97387585
49Jak-STAT signaling pathway_Homo sapiens_hsa046300.97119795
50Circadian entrainment_Homo sapiens_hsa047130.96782291
51One carbon pool by folate_Homo sapiens_hsa006700.94574720
52Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.93301704
53Arachidonic acid metabolism_Homo sapiens_hsa005900.92949752
54Glycerolipid metabolism_Homo sapiens_hsa005610.89586196
55Histidine metabolism_Homo sapiens_hsa003400.84675442
56Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84472441
57Fatty acid biosynthesis_Homo sapiens_hsa000610.80900151
58Lysine degradation_Homo sapiens_hsa003100.80582325
59Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.80489207
60Caffeine metabolism_Homo sapiens_hsa002320.74134598
61cAMP signaling pathway_Homo sapiens_hsa040240.73776771
62RNA degradation_Homo sapiens_hsa030180.72610290
63Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.71120605
64Platelet activation_Homo sapiens_hsa046110.70881391
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.70361881
66Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68922943
67Long-term depression_Homo sapiens_hsa047300.68516653
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.63519205
69Huntingtons disease_Homo sapiens_hsa050160.60186801
70RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.59915956
71Glycerophospholipid metabolism_Homo sapiens_hsa005640.58226757
72Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.55477236
73Renin secretion_Homo sapiens_hsa049240.54943418
74Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.50784999
75beta-Alanine metabolism_Homo sapiens_hsa004100.50772018
76Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.50561077
77Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.50041219
78Maturity onset diabetes of the young_Homo sapiens_hsa049500.48223916
79Insulin secretion_Homo sapiens_hsa049110.47867904
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.47366915
81Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47312371
82Vitamin digestion and absorption_Homo sapiens_hsa049770.46879894
83Dopaminergic synapse_Homo sapiens_hsa047280.45621274
84Intestinal immune network for IgA production_Homo sapiens_hsa046720.45365607
85Measles_Homo sapiens_hsa051620.44715584
86T cell receptor signaling pathway_Homo sapiens_hsa046600.44691574
87Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43620668
88Amphetamine addiction_Homo sapiens_hsa050310.42674220
89Protein export_Homo sapiens_hsa030600.41470624
90Purine metabolism_Homo sapiens_hsa002300.38833064
91Fatty acid degradation_Homo sapiens_hsa000710.38761621
92Inositol phosphate metabolism_Homo sapiens_hsa005620.37481436
93Cholinergic synapse_Homo sapiens_hsa047250.35893279
94SNARE interactions in vesicular transport_Homo sapiens_hsa041300.35657533
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.34193171
96Oxytocin signaling pathway_Homo sapiens_hsa049210.33523871
97Glycosaminoglycan degradation_Homo sapiens_hsa005310.32956273
98Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.31362375
99Sphingolipid metabolism_Homo sapiens_hsa006000.31306667
100Aldosterone synthesis and secretion_Homo sapiens_hsa049250.31115632

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »