Rank | Gene Set | Z-score |
---|---|---|
1 | detection of molecule of bacterial origin (GO:0032490) | 5.19814752 |
2 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.80746785 |
3 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.79044513 |
4 | cellular response to ethanol (GO:0071361) | 4.73394824 |
5 | cellular extravasation (GO:0045123) | 4.17548723 |
6 | positive regulation by symbiont of host defense response (GO:0052509) | 4.09804286 |
7 | modulation by symbiont of host defense response (GO:0052031) | 4.09804286 |
8 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.09804286 |
9 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.09804286 |
10 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.09804286 |
11 | modulation by symbiont of host immune response (GO:0052553) | 4.09804286 |
12 | neutrophil activation involved in immune response (GO:0002283) | 4.05672419 |
13 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.03069993 |
14 | detection of external biotic stimulus (GO:0098581) | 4.02925050 |
15 | detection of other organism (GO:0098543) | 4.02853168 |
16 | macrophage activation involved in immune response (GO:0002281) | 4.01170607 |
17 | response to peptidoglycan (GO:0032494) | 3.94605146 |
18 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.93675206 |
19 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.87367309 |
20 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.85583219 |
21 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.83010701 |
22 | microglial cell activation (GO:0001774) | 3.72558332 |
23 | B cell receptor signaling pathway (GO:0050853) | 3.65876968 |
24 | negative regulation of interleukin-12 production (GO:0032695) | 3.59530495 |
25 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.58962880 |
26 | positive regulation of interferon-alpha production (GO:0032727) | 3.58574367 |
27 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.58116925 |
28 | macrophage activation (GO:0042116) | 3.55060435 |
29 | detection of biotic stimulus (GO:0009595) | 3.49572324 |
30 | regulation of interferon-alpha production (GO:0032647) | 3.46425070 |
31 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.43692032 |
32 | iron ion import (GO:0097286) | 3.27075663 |
33 | detection of bacterium (GO:0016045) | 3.26481135 |
34 | negative regulation of cell killing (GO:0031342) | 3.21547670 |
35 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.21547670 |
36 | response to host immune response (GO:0052572) | 3.17436324 |
37 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.17436324 |
38 | T-helper 1 type immune response (GO:0042088) | 3.13731574 |
39 | regulation of gamma-delta T cell activation (GO:0046643) | 3.13228158 |
40 | neutrophil mediated immunity (GO:0002446) | 3.11917047 |
41 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.09413739 |
42 | immunoglobulin mediated immune response (GO:0016064) | 3.09275554 |
43 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.08310466 |
44 | positive regulation of interferon-beta production (GO:0032728) | 3.06362102 |
45 | negative regulation of B cell proliferation (GO:0030889) | 3.01009657 |
46 | response to hydroperoxide (GO:0033194) | 2.99849373 |
47 | hepatocyte apoptotic process (GO:0097284) | 2.98955391 |
48 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.98762287 |
49 | response to host (GO:0075136) | 2.98762287 |
50 | response to host defenses (GO:0052200) | 2.98762287 |
51 | regulation of macrophage cytokine production (GO:0010935) | 2.96748340 |
52 | myeloid cell activation involved in immune response (GO:0002275) | 2.95330670 |
53 | positive regulation of macrophage cytokine production (GO:0060907) | 2.93818039 |
54 | B cell proliferation (GO:0042100) | 2.91317718 |
55 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.87375051 |
56 | positive regulation of B cell differentiation (GO:0045579) | 2.80906733 |
57 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.77845907 |
58 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.76379854 |
59 | I-kappaB phosphorylation (GO:0007252) | 2.75591031 |
60 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 2.73236657 |
61 | regulation of mast cell activation (GO:0033003) | 2.72790806 |
62 | response to muramyl dipeptide (GO:0032495) | 2.72081810 |
63 | B cell mediated immunity (GO:0019724) | 2.71855646 |
64 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.70094663 |
65 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.68909197 |
66 | myeloid leukocyte mediated immunity (GO:0002444) | 2.68527419 |
67 | histone H3-K36 demethylation (GO:0070544) | 2.67452435 |
68 | negative regulation of T cell mediated immunity (GO:0002710) | 2.67150990 |
69 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.66408975 |
70 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.65168948 |
71 | neutrophil activation (GO:0042119) | 2.64064425 |
72 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.63619712 |
73 | positive regulation of mast cell activation (GO:0033005) | 2.62464040 |
74 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.62225563 |
75 | cellular response to type I interferon (GO:0071357) | 2.61836854 |
76 | type I interferon signaling pathway (GO:0060337) | 2.61836854 |
77 | response to type I interferon (GO:0034340) | 2.60572134 |
78 | germinal center formation (GO:0002467) | 2.59474148 |
79 | interleukin-6-mediated signaling pathway (GO:0070102) | 2.59388473 |
80 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.57658124 |
81 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.57658124 |
82 | regulation of B cell differentiation (GO:0045577) | 2.57008561 |
83 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.56287884 |
84 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.53216231 |
85 | nuclear pore complex assembly (GO:0051292) | 2.52455720 |
86 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.52010929 |
87 | respiratory burst (GO:0045730) | 2.51809947 |
88 | regulation of interferon-beta production (GO:0032648) | 2.51038890 |
89 | histone mRNA catabolic process (GO:0071044) | 2.49814870 |
90 | dendritic cell migration (GO:0036336) | 2.49571180 |
91 | adaptive immune response (GO:0002250) | 2.48687645 |
92 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.48540436 |
93 | response to interferon-alpha (GO:0035455) | 2.48113782 |
94 | negative regulation of interleukin-17 production (GO:0032700) | 2.47198918 |
95 | positive regulation of leukocyte degranulation (GO:0043302) | 2.45143973 |
96 | T cell migration (GO:0072678) | 2.44195515 |
97 | myeloid leukocyte activation (GO:0002274) | 2.44036559 |
98 | protein targeting to lysosome (GO:0006622) | 2.43127168 |
99 | establishment of protein localization to vacuole (GO:0072666) | 2.43127168 |
100 | protein targeting to vacuole (GO:0006623) | 2.43127168 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.70698650 |
2 | * IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.24998843 |
3 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.61353979 |
4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.98540159 |
5 | GATA1_22025678_ChIP-Seq_K562_Human | 2.97412527 |
6 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.84225040 |
7 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.71913836 |
8 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.68403648 |
9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.67463335 |
10 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.62084418 |
11 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.56612753 |
12 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.54588138 |
13 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.53394351 |
14 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.45239189 |
15 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.24701943 |
16 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.19910294 |
17 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.17704190 |
18 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.09315718 |
19 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.08967071 |
20 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.08292405 |
21 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.91137846 |
22 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.88862704 |
23 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.84255813 |
24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.78057757 |
25 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.75576232 |
26 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.66718871 |
27 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.65528193 |
28 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.62662109 |
29 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.60833777 |
30 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.60042266 |
31 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.59270369 |
32 | MYB_26560356_Chip-Seq_TH2_Human | 1.56604263 |
33 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.56365152 |
34 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.54154769 |
35 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.51846336 |
36 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.47882100 |
37 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.46351554 |
38 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.42143492 |
39 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.40456323 |
40 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.38985284 |
41 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.37985426 |
42 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.32229147 |
43 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.31860634 |
44 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.28537617 |
45 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.28537617 |
46 | MYB_26560356_Chip-Seq_TH1_Human | 1.27449219 |
47 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.25907298 |
48 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.25717805 |
49 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.23803785 |
50 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.22450248 |
51 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.22402794 |
52 | GATA3_26560356_Chip-Seq_TH2_Human | 1.21899906 |
53 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.21683323 |
54 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.21368690 |
55 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.18325692 |
56 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.18158272 |
57 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.17540515 |
58 | CJUN_26792858_Chip-Seq_BT549_Human | 1.16854612 |
59 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.16729898 |
60 | * RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.16515337 |
61 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.16149886 |
62 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.15207202 |
63 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.15150829 |
64 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.14918957 |
65 | * FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.13757067 |
66 | SPI1_23127762_ChIP-Seq_K562_Human | 1.12863485 |
67 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.12339706 |
68 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.12167329 |
69 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.11156534 |
70 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.10981165 |
71 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.09970911 |
72 | TP53_16413492_ChIP-PET_HCT116_Human | 1.09875044 |
73 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.09160830 |
74 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.08731438 |
75 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.08632597 |
76 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.08411916 |
77 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.07951086 |
78 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.04561231 |
79 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.04353204 |
80 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.04285351 |
81 | P300_19829295_ChIP-Seq_ESCs_Human | 1.03613954 |
82 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.02983752 |
83 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.02861903 |
84 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.02363116 |
85 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.01859755 |
86 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.01859755 |
87 | EWS_26573619_Chip-Seq_HEK293_Human | 1.01798572 |
88 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.01793067 |
89 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.01252299 |
90 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.00852406 |
91 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.00791594 |
92 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.00401962 |
93 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.00030603 |
94 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.99889004 |
95 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.97391678 |
96 | STAT3_23295773_ChIP-Seq_U87_Human | 0.96019165 |
97 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.95847322 |
98 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.95671662 |
99 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.95369061 |
100 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.94700190 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 3.58527304 |
2 | MP0003724_increased_susceptibility_to | 3.56070814 |
3 | MP0000569_abnormal_digit_pigmentation | 3.37006118 |
4 | MP0006054_spinal_hemorrhage | 3.14796761 |
5 | MP0003303_peritoneal_inflammation | 2.97387433 |
6 | MP0003300_gastrointestinal_ulcer | 2.46814000 |
7 | MP0002166_altered_tumor_susceptibility | 2.42686230 |
8 | MP0008057_abnormal_DNA_replication | 2.42054932 |
9 | MP0008260_abnormal_autophagy | 2.30456586 |
10 | MP0002419_abnormal_innate_immunity | 2.21651364 |
11 | MP0009785_altered_susceptibility_to | 2.17895241 |
12 | MP0001800_abnormal_humoral_immune | 2.14278642 |
13 | MP0010352_gastrointestinal_tract_polyps | 2.10492338 |
14 | MP0003828_pulmonary_edema | 2.09666515 |
15 | MP0000685_abnormal_immune_system | 2.07650225 |
16 | MP0010234_abnormal_vibrissa_follicle | 2.01067626 |
17 | MP0006082_CNS_inflammation | 1.95545106 |
18 | MP0005000_abnormal_immune_tolerance | 1.93672872 |
19 | MP0003191_abnormal_cellular_cholesterol | 1.92425361 |
20 | MP0002452_abnormal_antigen_presenting | 1.91686011 |
21 | MP0003436_decreased_susceptibility_to | 1.88863256 |
22 | MP0001790_abnormal_immune_system | 1.87879373 |
23 | MP0005387_immune_system_phenotype | 1.87879373 |
24 | MP0002009_preneoplasia | 1.79565985 |
25 | MP0002006_tumorigenesis | 1.76058846 |
26 | MP0002148_abnormal_hypersensitivity_rea | 1.75950428 |
27 | MP0002723_abnormal_immune_serum | 1.74851408 |
28 | MP0004883_abnormal_blood_vessel | 1.72347403 |
29 | MP0003172_abnormal_lysosome_physiology | 1.72042977 |
30 | MP0005025_abnormal_response_to | 1.65017396 |
31 | MP0002420_abnormal_adaptive_immunity | 1.62759082 |
32 | MP0003091_abnormal_cell_migration | 1.61590970 |
33 | MP0003763_abnormal_thymus_physiology | 1.61155268 |
34 | MP0001819_abnormal_immune_cell | 1.60979515 |
35 | MP0002396_abnormal_hematopoietic_system | 1.59730039 |
36 | MP0000465_gastrointestinal_hemorrhage | 1.59717905 |
37 | MP0005671_abnormal_response_to | 1.58974498 |
38 | MP0005464_abnormal_platelet_physiology | 1.58959117 |
39 | MP0003656_abnormal_erythrocyte_physiolo | 1.51379829 |
40 | MP0001545_abnormal_hematopoietic_system | 1.47736319 |
41 | MP0005397_hematopoietic_system_phenotyp | 1.47736319 |
42 | MP0004808_abnormal_hematopoietic_stem | 1.45531266 |
43 | MP0005164_abnormal_response_to | 1.41531099 |
44 | MP0005451_abnormal_body_composition | 1.39254534 |
45 | MP0002405_respiratory_system_inflammati | 1.38934504 |
46 | MP0004947_skin_inflammation | 1.38467028 |
47 | MP0003950_abnormal_plasma_membrane | 1.37664139 |
48 | MP0002398_abnormal_bone_marrow | 1.31820216 |
49 | MP0002138_abnormal_hepatobiliary_system | 1.29513337 |
50 | MP0001845_abnormal_inflammatory_respons | 1.27482127 |
51 | MP0000716_abnormal_immune_system | 1.26227503 |
52 | MP0010155_abnormal_intestine_physiology | 1.25805126 |
53 | MP0003221_abnormal_cardiomyocyte_apopto | 1.25562526 |
54 | MP0001533_abnormal_skeleton_physiology | 1.21863490 |
55 | MP0002998_abnormal_bone_remodeling | 1.20135872 |
56 | MP0001853_heart_inflammation | 1.19282647 |
57 | MP0001851_eye_inflammation | 1.19132555 |
58 | MP0000689_abnormal_spleen_morphology | 1.18948260 |
59 | MP0009764_decreased_sensitivity_to | 1.16974121 |
60 | MP0003448_altered_tumor_morphology | 1.14345489 |
61 | MP0000015_abnormal_ear_pigmentation | 1.14291843 |
62 | MP0003252_abnormal_bile_duct | 1.14084292 |
63 | MP0003183_abnormal_peptide_metabolism | 1.09044416 |
64 | MP0005310_abnormal_salivary_gland | 1.08832784 |
65 | MP0004484_altered_response_of | 1.07341262 |
66 | MP0010678_abnormal_skin_adnexa | 1.07338566 |
67 | MP0001915_intracranial_hemorrhage | 1.06935697 |
68 | MP0002722_abnormal_immune_system | 1.06305363 |
69 | MP0002877_abnormal_melanocyte_morpholog | 1.04395094 |
70 | MP0003690_abnormal_glial_cell | 1.04192505 |
71 | MP0000371_diluted_coat_color | 1.04091051 |
72 | MP0005058_abnormal_lysosome_morphology | 1.01364295 |
73 | MP0008469_abnormal_protein_level | 1.00635669 |
74 | MP0003566_abnormal_cell_adhesion | 0.99555772 |
75 | MP0000604_amyloidosis | 0.97626555 |
76 | MP0002429_abnormal_blood_cell | 0.96500122 |
77 | MP0009278_abnormal_bone_marrow | 0.96316748 |
78 | MP0002332_abnormal_exercise_endurance | 0.94905799 |
79 | MP0000858_altered_metastatic_potential | 0.94609722 |
80 | MP0003045_fibrosis | 0.90813850 |
81 | MP0000249_abnormal_blood_vessel | 0.86545380 |
82 | MP0008004_abnormal_stomach_pH | 0.86052012 |
83 | MP0003868_abnormal_feces_composition | 0.85235055 |
84 | MP0005174_abnormal_tail_pigmentation | 0.84817999 |
85 | MP0003075_altered_response_to | 0.83208715 |
86 | MP0008438_abnormal_cutaneous_collagen | 0.82886895 |
87 | MP0002132_abnormal_respiratory_system | 0.82011152 |
88 | MP0002254_reproductive_system_inflammat | 0.80941881 |
89 | MP0003195_calcinosis | 0.80404500 |
90 | MP0004084_abnormal_cardiac_muscle | 0.80238954 |
91 | MP0003787_abnormal_imprinting | 0.79702945 |
92 | MP0000343_altered_response_to | 0.79311650 |
93 | MP0005075_abnormal_melanosome_morpholog | 0.78724784 |
94 | MP0002133_abnormal_respiratory_system | 0.76539193 |
95 | MP0005388_respiratory_system_phenotype | 0.76539193 |
96 | MP0008877_abnormal_DNA_methylation | 0.76079417 |
97 | MP0005621_abnormal_cell_physiology | 0.74161575 |
98 | MP0000703_abnormal_thymus_morphology | 0.73139752 |
99 | MP0010307_abnormal_tumor_latency | 0.71387578 |
100 | MP0001958_emphysema | 0.70203031 |
Rank | Gene Set | Z-score |
---|---|---|
1 | T lymphocytopenia (HP:0005403) | 5.19203321 |
2 | Abnormality of T cell number (HP:0011839) | 4.74282346 |
3 | Recurrent bacterial skin infections (HP:0005406) | 4.61048378 |
4 | Recurrent abscess formation (HP:0002722) | 4.06722542 |
5 | Hematochezia (HP:0002573) | 3.85572021 |
6 | Eczematoid dermatitis (HP:0000976) | 3.78261364 |
7 | Retrobulbar optic neuritis (HP:0100654) | 3.65592894 |
8 | Optic neuritis (HP:0100653) | 3.65592894 |
9 | Spontaneous hematomas (HP:0007420) | 3.57229541 |
10 | Orchitis (HP:0100796) | 3.42108448 |
11 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.41013844 |
12 | Recurrent fungal infections (HP:0002841) | 3.36767328 |
13 | Myositis (HP:0100614) | 3.32190016 |
14 | Papillary thyroid carcinoma (HP:0002895) | 3.30359069 |
15 | Recurrent viral infections (HP:0004429) | 3.27446424 |
16 | Abnormality of macrophages (HP:0004311) | 3.18174315 |
17 | Thyroiditis (HP:0100646) | 3.17525654 |
18 | Recurrent skin infections (HP:0001581) | 3.06355901 |
19 | Abnormality of B cell number (HP:0010975) | 3.04830748 |
20 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.97968136 |
21 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.97968136 |
22 | Abnormality of glycolipid metabolism (HP:0010969) | 2.97968136 |
23 | B lymphocytopenia (HP:0010976) | 2.92795848 |
24 | Hypoplasia of the thymus (HP:0000778) | 2.91499773 |
25 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.89523365 |
26 | Recurrent cutaneous fungal infections (HP:0011370) | 2.86821597 |
27 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.86821597 |
28 | Myocardial infarction (HP:0001658) | 2.77056447 |
29 | Keratoconjunctivitis sicca (HP:0001097) | 2.75895741 |
30 | Meningitis (HP:0001287) | 2.75201510 |
31 | Gingival bleeding (HP:0000225) | 2.71722424 |
32 | Gastrointestinal infarctions (HP:0005244) | 2.71185096 |
33 | Gingivitis (HP:0000230) | 2.65856276 |
34 | Panhypogammaglobulinemia (HP:0003139) | 2.65260973 |
35 | Conjunctival telangiectasia (HP:0000524) | 2.64066129 |
36 | Abnormality of T cells (HP:0002843) | 2.61094865 |
37 | Arterial thrombosis (HP:0004420) | 2.59790961 |
38 | Hemoptysis (HP:0002105) | 2.59445135 |
39 | Osteomyelitis (HP:0002754) | 2.58383439 |
40 | Subacute progressive viral hepatitis (HP:0006572) | 2.57362263 |
41 | Mediastinal lymphadenopathy (HP:0100721) | 2.57024868 |
42 | Stomatitis (HP:0010280) | 2.56468870 |
43 | Eosinophilia (HP:0001880) | 2.52235382 |
44 | Pulmonary infiltrates (HP:0002113) | 2.49440915 |
45 | Keratoconjunctivitis (HP:0001096) | 2.48500508 |
46 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.42791837 |
47 | Leukocytosis (HP:0001974) | 2.42600229 |
48 | Peritonitis (HP:0002586) | 2.40649468 |
49 | Vasculitis (HP:0002633) | 2.40079075 |
50 | Cellulitis (HP:0100658) | 2.37827836 |
51 | Recurrent bronchitis (HP:0002837) | 2.36559346 |
52 | Periodontitis (HP:0000704) | 2.34401434 |
53 | Thyroid carcinoma (HP:0002890) | 2.33141823 |
54 | Chronic diarrhea (HP:0002028) | 2.32591996 |
55 | Chest pain (HP:0100749) | 2.32082037 |
56 | Absent frontal sinuses (HP:0002688) | 2.28867284 |
57 | Fatigue (HP:0012378) | 2.28010108 |
58 | Autoimmune hemolytic anemia (HP:0001890) | 2.25449569 |
59 | Disinhibition (HP:0000734) | 2.21369516 |
60 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.20428349 |
61 | Granulocytopenia (HP:0001913) | 2.15483023 |
62 | Viral hepatitis (HP:0006562) | 2.14994259 |
63 | Pulmonary embolism (HP:0002204) | 2.14373775 |
64 | Spondylolisthesis (HP:0003302) | 2.11439595 |
65 | Mucosal telangiectasiae (HP:0100579) | 2.09169476 |
66 | Urticaria (HP:0001025) | 2.09166236 |
67 | Lower limb hyperreflexia (HP:0002395) | 2.08503105 |
68 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.03224794 |
69 | Amaurosis fugax (HP:0100576) | 2.01494415 |
70 | Acute myeloid leukemia (HP:0004808) | 2.00568454 |
71 | Encephalitis (HP:0002383) | 1.97803877 |
72 | Agammaglobulinemia (HP:0004432) | 1.96368568 |
73 | Abnormality of eosinophils (HP:0001879) | 1.95826858 |
74 | Loss of speech (HP:0002371) | 1.95434057 |
75 | Spinal cord lesions (HP:0100561) | 1.93448563 |
76 | Syringomyelia (HP:0003396) | 1.93448563 |
77 | Epistaxis (HP:0000421) | 1.93253827 |
78 | Thickened calvaria (HP:0002684) | 1.92326721 |
79 | Increased CSF protein (HP:0002922) | 1.91082513 |
80 | Combined immunodeficiency (HP:0005387) | 1.88730928 |
81 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.86433895 |
82 | Severe combined immunodeficiency (HP:0004430) | 1.86329859 |
83 | Inflammation of the large intestine (HP:0002037) | 1.83080894 |
84 | Albinism (HP:0001022) | 1.82656768 |
85 | Thrombocytosis (HP:0001894) | 1.82649673 |
86 | Sepsis (HP:0100806) | 1.82062792 |
87 | Stomach cancer (HP:0012126) | 1.81378242 |
88 | Hypoproteinemia (HP:0003075) | 1.81018271 |
89 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.80005309 |
90 | Osteolytic defects of the hand bones (HP:0009699) | 1.80005309 |
91 | Recurrent pneumonia (HP:0006532) | 1.79881838 |
92 | Esophageal varix (HP:0002040) | 1.79191122 |
93 | Colitis (HP:0002583) | 1.78704815 |
94 | Gangrene (HP:0100758) | 1.78332896 |
95 | Scanning speech (HP:0002168) | 1.78016606 |
96 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.77203511 |
97 | Abnormal platelet volume (HP:0011876) | 1.76092111 |
98 | Curly hair (HP:0002212) | 1.76038076 |
99 | IgA deficiency (HP:0002720) | 1.75891992 |
100 | IgM deficiency (HP:0002850) | 1.73476946 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 2.97907542 |
2 | BLK | 2.97288202 |
3 | MAP3K14 | 2.89058613 |
4 | TYK2 | 2.59687089 |
5 | PIK3CG | 2.38029115 |
6 | ACVR1B | 2.21859873 |
7 | EIF2AK3 | 2.21533975 |
8 | BMPR2 | 2.17110562 |
9 | TEC | 2.16677491 |
10 | JAK1 | 2.16116977 |
11 | TAOK3 | 2.05983880 |
12 | TGFBR2 | 1.97328712 |
13 | JAK3 | 1.95971627 |
14 | MAP2K3 | 1.95432188 |
15 | IRAK4 | 1.91364768 |
16 | CSK | 1.90299229 |
17 | RIPK4 | 1.85259860 |
18 | NEK9 | 1.76857825 |
19 | TRPM7 | 1.72241831 |
20 | FGFR3 | 1.67896264 |
21 | IKBKE | 1.59347273 |
22 | STK24 | 1.57633826 |
23 | FES | 1.57143397 |
24 | MAP3K13 | 1.56908076 |
25 | CDK6 | 1.55295578 |
26 | KIT | 1.54815341 |
27 | YES1 | 1.51940015 |
28 | BTK | 1.49999622 |
29 | ZAP70 | 1.42484730 |
30 | FGR | 1.42077745 |
31 | STK38L | 1.36599004 |
32 | SYK | 1.35653512 |
33 | NLK | 1.34286159 |
34 | TIE1 | 1.34079125 |
35 | MAP3K6 | 1.30086448 |
36 | BRD4 | 1.29953143 |
37 | HCK | 1.24633641 |
38 | ERBB3 | 1.23431754 |
39 | MAP3K2 | 1.18198704 |
40 | IRAK1 | 1.17443561 |
41 | JAK2 | 1.13060334 |
42 | LYN | 1.09897767 |
43 | MAP4K1 | 1.07066130 |
44 | CSF1R | 1.06820441 |
45 | ITK | 1.01758841 |
46 | STK10 | 1.00887787 |
47 | SGK2 | 0.97947079 |
48 | AKT3 | 0.96017213 |
49 | LCK | 0.94904657 |
50 | SGK3 | 0.94535421 |
51 | CAMKK2 | 0.92101246 |
52 | EGFR | 0.91758657 |
53 | TXK | 0.89808490 |
54 | MAP3K10 | 0.89408712 |
55 | TBK1 | 0.88646487 |
56 | SCYL2 | 0.86270704 |
57 | MELK | 0.85101768 |
58 | PBK | 0.84460860 |
59 | STK3 | 0.83843870 |
60 | MST4 | 0.80921855 |
61 | TGFBR1 | 0.79623981 |
62 | BMPR1B | 0.77922443 |
63 | IKBKB | 0.76710941 |
64 | FER | 0.74527297 |
65 | MAP3K5 | 0.73715766 |
66 | IRAK2 | 0.72083525 |
67 | MATK | 0.71013163 |
68 | NEK6 | 0.67287442 |
69 | MAPK7 | 0.67174127 |
70 | PLK2 | 0.67118936 |
71 | GRK7 | 0.66762314 |
72 | LATS1 | 0.66136227 |
73 | MARK3 | 0.65701246 |
74 | PTK2B | 0.60865641 |
75 | MAP3K3 | 0.59838371 |
76 | BRSK2 | 0.57550890 |
77 | WNK1 | 0.57316844 |
78 | NUAK1 | 0.56046435 |
79 | PDGFRB | 0.55620422 |
80 | ABL1 | 0.55492277 |
81 | KSR1 | 0.55064712 |
82 | OXSR1 | 0.51943670 |
83 | IGF1R | 0.50728207 |
84 | MAP3K1 | 0.49544428 |
85 | CAMK1G | 0.47555880 |
86 | GRK6 | 0.46266454 |
87 | PIM1 | 0.46187529 |
88 | RAF1 | 0.43764922 |
89 | PDK1 | 0.43704724 |
90 | PRPF4B | 0.43699529 |
91 | RPS6KB1 | 0.43284627 |
92 | FGFR2 | 0.42294879 |
93 | MOS | 0.42246626 |
94 | MAP3K12 | 0.38545704 |
95 | CHUK | 0.38424625 |
96 | INSR | 0.38108584 |
97 | CDK12 | 0.34890214 |
98 | CLK1 | 0.32724581 |
99 | PRKCQ | 0.31614382 |
100 | KSR2 | 0.31445212 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.84668575 |
2 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.37535600 |
3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.21823320 |
4 | Allograft rejection_Homo sapiens_hsa05330 | 2.13865688 |
5 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.11428861 |
6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.10089403 |
7 | Tuberculosis_Homo sapiens_hsa05152 | 2.02238057 |
8 | Asthma_Homo sapiens_hsa05310 | 2.01297021 |
9 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.98991475 |
10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.93065700 |
11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.91313015 |
12 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.87435291 |
13 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.85103596 |
14 | Legionellosis_Homo sapiens_hsa05134 | 1.76559924 |
15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.76380376 |
16 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.69691167 |
17 | Influenza A_Homo sapiens_hsa05164 | 1.68997404 |
18 | Measles_Homo sapiens_hsa05162 | 1.68478941 |
19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.65307352 |
20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.58654810 |
21 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.58389654 |
22 | Malaria_Homo sapiens_hsa05144 | 1.45633213 |
23 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.38813872 |
24 | Viral myocarditis_Homo sapiens_hsa05416 | 1.37836302 |
25 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.34665883 |
26 | Phagosome_Homo sapiens_hsa04145 | 1.31128394 |
27 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.30823945 |
28 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.29776114 |
29 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.29098884 |
30 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.28459471 |
31 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.27570400 |
32 | Platelet activation_Homo sapiens_hsa04611 | 1.27542143 |
33 | Lysosome_Homo sapiens_hsa04142 | 1.26474008 |
34 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.24294873 |
35 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.21534350 |
36 | Hepatitis B_Homo sapiens_hsa05161 | 1.21390767 |
37 | Other glycan degradation_Homo sapiens_hsa00511 | 1.19194733 |
38 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.18342536 |
39 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.17849209 |
40 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.17172036 |
41 | Pertussis_Homo sapiens_hsa05133 | 1.14898282 |
42 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.14797562 |
43 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.11385906 |
44 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.10767788 |
45 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.09965758 |
46 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.03792019 |
47 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.03572919 |
48 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.03268884 |
49 | Hepatitis C_Homo sapiens_hsa05160 | 1.02911975 |
50 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.02022126 |
51 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.99652715 |
52 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.98606278 |
53 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.97332158 |
54 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.96145884 |
55 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.94212790 |
56 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.93401776 |
57 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.91203738 |
58 | Shigellosis_Homo sapiens_hsa05131 | 0.89096286 |
59 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.88286500 |
60 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.84357890 |
61 | Amoebiasis_Homo sapiens_hsa05146 | 0.81330099 |
62 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.76680223 |
63 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.76426946 |
64 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.75983359 |
65 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.71030059 |
66 | Apoptosis_Homo sapiens_hsa04210 | 0.70837524 |
67 | Salmonella infection_Homo sapiens_hsa05132 | 0.69932563 |
68 | Prostate cancer_Homo sapiens_hsa05215 | 0.68294098 |
69 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.67168702 |
70 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.66183625 |
71 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.65424090 |
72 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.65382983 |
73 | Adherens junction_Homo sapiens_hsa04520 | 0.65338163 |
74 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.62889408 |
75 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.61281814 |
76 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.60631764 |
77 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.59420290 |
78 | Focal adhesion_Homo sapiens_hsa04510 | 0.59077058 |
79 | Endometrial cancer_Homo sapiens_hsa05213 | 0.57394008 |
80 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.55952825 |
81 | Colorectal cancer_Homo sapiens_hsa05210 | 0.55286087 |
82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.54438214 |
83 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.52724541 |
84 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.52701000 |
85 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.52478199 |
86 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.51041052 |
87 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.50641500 |
88 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.48609392 |
89 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.48359382 |
90 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.47601776 |
91 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.47235577 |
92 | HTLV-I infection_Homo sapiens_hsa05166 | 0.47148644 |
93 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.46974168 |
94 | Insulin resistance_Homo sapiens_hsa04931 | 0.45513522 |
95 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.43857803 |
96 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.42375077 |
97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.40354103 |
98 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.35745724 |
99 | Glioma_Homo sapiens_hsa05214 | 0.34849226 |
100 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.34223039 |