KIAA1191

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)4.41743828
2nucleobase catabolic process (GO:0046113)3.66150954
3paraxial mesoderm development (GO:0048339)3.43996873
4protein retention in ER lumen (GO:0006621)2.93665398
5cell migration in hindbrain (GO:0021535)2.93510837
6postsynaptic membrane organization (GO:0001941)2.92748569
7neuron recognition (GO:0008038)2.72839604
8maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.68025503
9regulation of short-term neuronal synaptic plasticity (GO:0048172)2.63608633
10positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.63473959
11axonal fasciculation (GO:0007413)2.63391509
12synaptic vesicle docking involved in exocytosis (GO:0016081)2.60851593
13axon extension (GO:0048675)2.59654932
14synaptic vesicle maturation (GO:0016188)2.58994054
15presynaptic membrane assembly (GO:0097105)2.51800973
16glutamate secretion (GO:0014047)2.50222229
17layer formation in cerebral cortex (GO:0021819)2.48089527
18substrate-independent telencephalic tangential migration (GO:0021826)2.46827389
19substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.46827389
20L-serine metabolic process (GO:0006563)2.43238560
21establishment of mitochondrion localization (GO:0051654)2.41832222
22vocalization behavior (GO:0071625)2.39699375
23cerebral cortex radially oriented cell migration (GO:0021799)2.37625731
24neuron cell-cell adhesion (GO:0007158)2.33790986
25neuron projection extension involved in neuron projection guidance (GO:1902284)2.33130410
26axon extension involved in axon guidance (GO:0048846)2.33130410
27positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.31623359
28ganglion development (GO:0061548)2.29338142
29presynaptic membrane organization (GO:0097090)2.29257332
30neuron projection extension (GO:1990138)2.26231901
31cellular protein complex localization (GO:0034629)2.25938352
32histone arginine methylation (GO:0034969)2.24829267
33mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.24239630
34COPI coating of Golgi vesicle (GO:0048205)2.22714927
35Golgi transport vesicle coating (GO:0048200)2.22714927
36cholesterol biosynthetic process (GO:0006695)2.19377575
37synaptic vesicle exocytosis (GO:0016079)2.17436573
38regulation of synaptic vesicle exocytosis (GO:2000300)2.14918222
39protein localization to synapse (GO:0035418)2.14736433
40positive regulation of synapse assembly (GO:0051965)2.10751807
41gamma-aminobutyric acid transport (GO:0015812)2.10500459
42negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.10285737
43positive regulation of dendritic spine morphogenesis (GO:0061003)2.07185745
44protein complex localization (GO:0031503)2.04501886
45sterol biosynthetic process (GO:0016126)2.03804683
46vitamin transmembrane transport (GO:0035461)2.02281406
47peptidyl-arginine omega-N-methylation (GO:0035247)2.00728849
48protein neddylation (GO:0045116)2.00388808
49ventricular cardiac muscle cell development (GO:0055015)2.00279755
50hippocampus development (GO:0021766)1.98479196
51behavioral response to nicotine (GO:0035095)1.97863465
52notochord development (GO:0030903)1.97733960
53hippo signaling (GO:0035329)1.97272841
54establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)1.97178237
55regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act1.96083792
56planar cell polarity pathway involved in neural tube closure (GO:0090179)1.95414116
57ephrin receptor signaling pathway (GO:0048013)1.94237617
58regulation of synaptic vesicle transport (GO:1902803)1.93300279
59cell communication by electrical coupling (GO:0010644)1.93070171
60neuronal ion channel clustering (GO:0045161)1.91885859
61spinal cord development (GO:0021510)1.91047172
62G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071991.90467924
63regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)1.90183759
64negative chemotaxis (GO:0050919)1.89362154
65synaptic vesicle endocytosis (GO:0048488)1.89247759
66dendritic spine organization (GO:0097061)1.88969092
67establishment of monopolar cell polarity (GO:0061162)1.88372711
68establishment or maintenance of monopolar cell polarity (GO:0061339)1.88372711
69negative regulation of microtubule polymerization (GO:0031115)1.88271514
70neurotransmitter-gated ion channel clustering (GO:0072578)1.88000723
71sequestering of actin monomers (GO:0042989)1.87060335
72apical protein localization (GO:0045176)1.86591620
73calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)1.86518130
74negative regulation of chondrocyte differentiation (GO:0032331)1.85752114
75synapse assembly (GO:0007416)1.85388061
76limb bud formation (GO:0060174)1.84888788
77cerebral cortex cell migration (GO:0021795)1.84749104
78dendrite morphogenesis (GO:0048813)1.84687567
79positive regulation of mitochondrial fission (GO:0090141)1.84226614
80negative regulation of synaptic transmission, GABAergic (GO:0032229)1.83850220
81negative regulation of catenin import into nucleus (GO:0035414)1.83553331
82neurotransmitter secretion (GO:0007269)1.83473483
83establishment or maintenance of apical/basal cell polarity (GO:0035088)1.83373323
84establishment or maintenance of bipolar cell polarity (GO:0061245)1.83373323
85ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043161.83341103
86peptidyl-cysteine modification (GO:0018198)1.82900813
87regulation of synapse assembly (GO:0051963)1.82020873
88nonmotile primary cilium assembly (GO:0035058)1.81740917
89regulation of retinoic acid receptor signaling pathway (GO:0048385)1.81069829
90L-serine transport (GO:0015825)1.80621922
91developmental cell growth (GO:0048588)1.80018706
92asymmetric protein localization (GO:0008105)1.79914365
93neuronal action potential propagation (GO:0019227)1.79439131
94regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)1.77579283
95convergent extension (GO:0060026)1.77172307
96protein insertion into membrane (GO:0051205)1.76800326
97olfactory bulb development (GO:0021772)1.76178140
98Wnt signaling pathway, planar cell polarity pathway (GO:0060071)1.75637135
99cell communication involved in cardiac conduction (GO:0086065)1.75302479
100sodium ion export (GO:0071436)1.74457005

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.62737171
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.00335956
3CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.35396226
4EZH2_22144423_ChIP-Seq_EOC_Human2.31350068
5NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.19645457
6ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.06195440
7ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.90077980
8TRIM28_21343339_ChIP-Seq_HEK293_Human1.82883777
9EED_16625203_ChIP-ChIP_MESCs_Mouse1.74281296
10EZH2_27304074_Chip-Seq_ESCs_Mouse1.72362398
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.64294289
12EZH2_18974828_ChIP-Seq_MESCs_Mouse1.64163205
13RNF2_18974828_ChIP-Seq_MESCs_Mouse1.64163205
14ZFP281_18757296_ChIP-ChIP_E14_Mouse1.61155316
15THAP11_20581084_ChIP-Seq_MESCs_Mouse1.57373861
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.52909569
17PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.52906878
18SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.49904930
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.46308186
20POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.46236893
21WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.46186089
22AR_21909140_ChIP-Seq_LNCAP_Human1.45763982
23WT1_19549856_ChIP-ChIP_CCG9911_Human1.40393398
24REST_18959480_ChIP-ChIP_MESCs_Mouse1.38323101
25SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.36301494
26JARID2_20064375_ChIP-Seq_MESCs_Mouse1.35287906
27SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.34270910
28SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.31481209
29SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.29908582
30EZH2_27294783_Chip-Seq_ESCs_Mouse1.28384554
31OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.25417495
32CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.23478907
33REST_21632747_ChIP-Seq_MESCs_Mouse1.22921091
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.22547965
35JARID2_20075857_ChIP-Seq_MESCs_Mouse1.22546850
36RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.22348352
37SOX2_18555785_ChIP-Seq_MESCs_Mouse1.20947800
38TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.18913772
39ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.18473516
40CLOCK_20551151_ChIP-Seq_293T_Human1.18321441
41TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16679615
42CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.16412733
43SUZ12_27294783_Chip-Seq_ESCs_Mouse1.12637245
44XRN2_22483619_ChIP-Seq_HELA_Human1.12558681
45SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.12386351
46PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.12080644
47TP53_20018659_ChIP-ChIP_R1E_Mouse1.11306747
48RNF2_27304074_Chip-Seq_NSC_Mouse1.10920817
49RNF2_27304074_Chip-Seq_ESCs_Mouse1.10404443
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.10019494
51POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.08537713
52ERG_21242973_ChIP-ChIP_JURKAT_Human1.07980909
53RARB_27405468_Chip-Seq_BRAIN_Mouse1.07413550
54BMI1_23680149_ChIP-Seq_NPCS_Mouse1.06998026
55SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.06357808
56GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.05523954
57TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.05036754
58NANOG_21062744_ChIP-ChIP_HESCs_Human1.04668324
59HIF1A_21447827_ChIP-Seq_MCF-7_Human1.04483816
60GATA1_26923725_Chip-Seq_HPCs_Mouse1.04099672
61CREB1_15753290_ChIP-ChIP_HEK293T_Human1.04064409
62SOX2_16153702_ChIP-ChIP_HESCs_Human1.02459065
63SRY_22984422_ChIP-ChIP_TESTIS_Rat1.01778116
64RBPJ_22232070_ChIP-Seq_NCS_Mouse1.01295683
65MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.00758999
66TET1_21490601_ChIP-Seq_MESCs_Mouse0.98739031
67GBX2_23144817_ChIP-Seq_PC3_Human0.98375095
68MTF2_20144788_ChIP-Seq_MESCs_Mouse0.98021734
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97264730
70SALL1_21062744_ChIP-ChIP_HESCs_Human0.96479570
71REST_19997604_ChIP-ChIP_NEURONS_Mouse0.96401174
72KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.95316730
73EOMES_21245162_ChIP-Seq_HESCs_Human0.95305975
74RING1B_27294783_Chip-Seq_NPCs_Mouse0.94531385
75CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93639366
76MYC_18555785_ChIP-Seq_MESCs_Mouse0.92355484
77ISL1_27105846_Chip-Seq_CPCs_Mouse0.91387181
78ZNF263_19887448_ChIP-Seq_K562_Human0.90336538
79EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.87741509
80POU5F1_16153702_ChIP-ChIP_HESCs_Human0.87688787
81POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.87586285
82RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.87273886
83NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.86987582
84FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.86209615
85RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.85480107
86NANOG_16153702_ChIP-ChIP_HESCs_Human0.85353210
87EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.85311235
88ZFX_18555785_ChIP-Seq_MESCs_Mouse0.84373155
89KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.84333256
90SOX9_26525672_Chip-Seq_HEART_Mouse0.83534352
91TTF2_22483619_ChIP-Seq_HELA_Human0.83469328
92SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.81439738
93ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.81427762
94SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.81254171
95TBX3_20139965_ChIP-Seq_MESCs_Mouse0.80136197
96TBX3_20139965_ChIP-Seq_ESCs_Mouse0.79918980
97POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.79226299
98SOX17_20123909_ChIP-Seq_XEN_Mouse0.77834860
99TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.77683767
100KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.77665327

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting2.37479143
2MP0004859_abnormal_synaptic_plasticity2.23268460
3MP0001529_abnormal_vocalization2.21448511
4MP0004270_analgesia2.05922073
5MP0010030_abnormal_orbit_morphology2.05058100
6MP0002653_abnormal_ependyma_morphology2.03873213
7MP0005499_abnormal_olfactory_system1.94783136
8MP0005394_taste/olfaction_phenotype1.94783136
9MP0002102_abnormal_ear_morphology1.91710720
10MP0000778_abnormal_nervous_system1.90666530
11MP0004272_abnormal_basement_membrane1.81197624
12MP0003880_abnormal_central_pattern1.80407956
13MP0005623_abnormal_meninges_morphology1.80242737
14MP0003123_paternal_imprinting1.79358995
15MP0008789_abnormal_olfactory_epithelium1.77284302
16MP0001984_abnormal_olfaction1.65034328
17MP0009780_abnormal_chondrocyte_physiolo1.62295360
18MP0000537_abnormal_urethra_morphology1.56094861
19MP0001299_abnormal_eye_distance/1.51933001
20MP0003385_abnormal_body_wall1.47387409
21MP0000049_abnormal_middle_ear1.45440109
22MP0002822_catalepsy1.44717877
23MP0000534_abnormal_ureter_morphology1.42436752
24MP0003942_abnormal_urinary_system1.42303790
25MP0003941_abnormal_skin_development1.41463302
26MP0006292_abnormal_olfactory_placode1.41335085
27MP0005257_abnormal_intraocular_pressure1.39822802
28MP0002233_abnormal_nose_morphology1.39443550
29MP0000566_synostosis1.35781805
30MP0003755_abnormal_palate_morphology1.34544937
31MP0002697_abnormal_eye_size1.30592481
32MP0003937_abnormal_limbs/digits/tail_de1.28755978
33MP0001293_anophthalmia1.28602635
34MP0003635_abnormal_synaptic_transmissio1.28456302
35MP0005409_darkened_coat_color1.26155800
36MP0003136_yellow_coat_color1.24832283
37MP0009053_abnormal_anal_canal1.19945348
38MP0003119_abnormal_digestive_system1.18441618
39MP0003861_abnormal_nervous_system1.18345717
40MP0006276_abnormal_autonomic_nervous1.17105019
41MP0002234_abnormal_pharynx_morphology1.16105518
42MP0002063_abnormal_learning/memory/cond1.15451033
43MP0005423_abnormal_somatic_nervous1.13768744
44MP0005187_abnormal_penis_morphology1.12590979
45MP0003121_genomic_imprinting1.12279349
46MP0000955_abnormal_spinal_cord1.12124494
47MP0003890_abnormal_embryonic-extraembry1.11790025
48MP0002938_white_spotting1.10959854
49MP0002734_abnormal_mechanical_nocicepti1.09785413
50MP0004811_abnormal_neuron_physiology1.08887376
51MP0001286_abnormal_eye_development1.05925621
52MP0001188_hyperpigmentation1.03980218
53MP0000579_abnormal_nail_morphology1.02503781
54MP0002184_abnormal_innervation1.01460023
55MP0005248_abnormal_Harderian_gland1.00242201
56MP0003315_abnormal_perineum_morphology0.99861105
57MP0000762_abnormal_tongue_morphology0.99651896
58MP0003705_abnormal_hypodermis_morpholog0.98970732
59MP0003329_amyloid_beta_deposits0.96441655
60MP0000751_myopathy0.95717927
61MP0002152_abnormal_brain_morphology0.95246629
62MP0002557_abnormal_social/conspecific_i0.94668975
63MP0002572_abnormal_emotion/affect_behav0.94598184
64MP0003938_abnormal_ear_development0.94157434
65MP0003935_abnormal_craniofacial_develop0.93419002
66MP0002882_abnormal_neuron_morphology0.92360467
67MP0003879_abnormal_hair_cell0.92194724
68MP0008932_abnormal_embryonic_tissue0.90534274
69MP0008438_abnormal_cutaneous_collagen0.90479412
70MP0002272_abnormal_nervous_system0.90298056
71MP0002249_abnormal_larynx_morphology0.88128908
72MP0002909_abnormal_adrenal_gland0.87648380
73MP0004133_heterotaxia0.87329295
74MP0004233_abnormal_muscle_weight0.85774345
75MP0002084_abnormal_developmental_patter0.85679407
76MP0002081_perinatal_lethality0.85389769
77MP0001346_abnormal_lacrimal_gland0.84882895
78MP0002064_seizures0.84701148
79MP0002092_abnormal_eye_morphology0.83706505
80MP0009745_abnormal_behavioral_response0.83365281
81MP0001502_abnormal_circadian_rhythm0.81199941
82MP0010368_abnormal_lymphatic_system0.81066538
83MP0009250_abnormal_appendicular_skeleto0.80710772
84MP0002752_abnormal_somatic_nervous0.79215547
85MP0002085_abnormal_embryonic_tissue0.78860613
86MP0002116_abnormal_craniofacial_bone0.78802942
87MP0009672_abnormal_birth_weight0.77584283
88MP0009384_cardiac_valve_regurgitation0.77517612
89MP0005197_abnormal_uvea_morphology0.76203571
90MP0002160_abnormal_reproductive_system0.73999940
91MP0000647_abnormal_sebaceous_gland0.73638757
92MP0001270_distended_abdomen0.73118934
93MP0001968_abnormal_touch/_nociception0.71540866
94MP0000026_abnormal_inner_ear0.70848592
95MP0004924_abnormal_behavior0.70801496
96MP0005386_behavior/neurological_phenoty0.70801496
97MP0000462_abnormal_digestive_system0.66739953
98MP0001340_abnormal_eyelid_morphology0.66525582
99MP0005391_vision/eye_phenotype0.65925326
100MP0002066_abnormal_motor_capabilities/c0.65722426

Predicted human phenotypes

RankGene SetZ-score
1Cortical dysplasia (HP:0002539)2.90961424
2Abnormality of glycolysis (HP:0004366)2.68002067
3Hepatoblastoma (HP:0002884)2.48563405
4Myokymia (HP:0002411)2.40039414
5Increased serum pyruvate (HP:0003542)2.36452567
6Split foot (HP:0001839)2.23215615
7Drooling (HP:0002307)2.04455940
8Gait imbalance (HP:0002141)2.03855864
9Pheochromocytoma (HP:0002666)2.00698161
10Retinal dysplasia (HP:0007973)1.99580443
11Vaginal atresia (HP:0000148)1.94954597
12Anophthalmia (HP:0000528)1.88568123
13Limb dystonia (HP:0002451)1.87262316
14Nephrogenic diabetes insipidus (HP:0009806)1.83596904
15Adrenal hypoplasia (HP:0000835)1.82022332
16High anterior hairline (HP:0009890)1.81912850
17Congenital primary aphakia (HP:0007707)1.81407920
18Genital tract atresia (HP:0001827)1.80359504
19Premature rupture of membranes (HP:0001788)1.77403114
20Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.75005089
21Choanal stenosis (HP:0000452)1.73712901
22Shallow orbits (HP:0000586)1.73567581
23Lissencephaly (HP:0001339)1.73166640
24Aplasia/Hypoplasia of the brainstem (HP:0007362)1.71375060
25Hypoplasia of the brainstem (HP:0002365)1.71375060
26Neuroendocrine neoplasm (HP:0100634)1.70473557
27Hypoglycemic seizures (HP:0002173)1.69928773
28Excessive salivation (HP:0003781)1.68531703
29Delayed CNS myelination (HP:0002188)1.67530183
30Hand muscle atrophy (HP:0009130)1.64689104
31Occipital encephalocele (HP:0002085)1.62916137
32Spastic diplegia (HP:0001264)1.62886946
33Upper limb muscle weakness (HP:0003484)1.62226300
34Amblyopia (HP:0000646)1.62002536
35Polyphagia (HP:0002591)1.59552122
36Myelomeningocele (HP:0002475)1.59389074
37Spastic tetraplegia (HP:0002510)1.59306894
38Exercise-induced muscle cramps (HP:0003710)1.57886120
39Spinal rigidity (HP:0003306)1.55594010
40Protrusio acetabuli (HP:0003179)1.55214287
41Dental crowding (HP:0000678)1.53862663
42Hydroureter (HP:0000072)1.53284561
43Poor coordination (HP:0002370)1.52538015
44Renal hypoplasia (HP:0000089)1.52372670
45Focal motor seizures (HP:0011153)1.51964346
46Abnormality of dentin (HP:0010299)1.51728334
47Bifid tongue (HP:0010297)1.50630949
48Absent eyebrow (HP:0002223)1.48572886
49Neoplasm of the peripheral nervous system (HP:0100007)1.47998307
50Medial flaring of the eyebrow (HP:0010747)1.45208664
51Focal seizures (HP:0007359)1.44478364
52Coronal craniosynostosis (HP:0004440)1.44440633
53Renal dysplasia (HP:0000110)1.42502010
54Partial duplication of thumb phalanx (HP:0009944)1.41735951
55Abnormality of the labia minora (HP:0012880)1.41659534
56Mutism (HP:0002300)1.39468539
57Labial hypoplasia (HP:0000066)1.39439145
58Generalized hypotonia (HP:0001290)1.39356675
59Micropenis (HP:0000054)1.39282689
60Exotropia (HP:0000577)1.38968251
61Abnormality of the aortic arch (HP:0012303)1.37781520
62Hypercalciuria (HP:0002150)1.37242393
63Scrotal hypoplasia (HP:0000046)1.36679389
64Hypoventilation (HP:0002791)1.36563610
65Generalized tonic-clonic seizures (HP:0002069)1.35977231
66Hypoplastic female external genitalia (HP:0012815)1.35896850
67Specific learning disability (HP:0001328)1.35621763
68Poor suck (HP:0002033)1.35611517
69Hypoplastic pelvis (HP:0008839)1.34075627
70Morphological abnormality of the middle ear (HP:0008609)1.33891093
71Abnormality of the lower motor neuron (HP:0002366)1.33874062
72Abnormal lung lobation (HP:0002101)1.33606146
73Missing ribs (HP:0000921)1.33508689
74Urinary urgency (HP:0000012)1.33427586
75Sleep apnea (HP:0010535)1.32322273
76Diastasis recti (HP:0001540)1.31898566
77Abnormality of magnesium homeostasis (HP:0004921)1.31087019
78Cutaneous finger syndactyly (HP:0010554)1.30587685
79Upper limb amyotrophy (HP:0009129)1.30506787
80Distal upper limb amyotrophy (HP:0007149)1.30506787
81Septo-optic dysplasia (HP:0100842)1.29360161
82Stenosis of the external auditory canal (HP:0000402)1.29224875
83Bicornuate uterus (HP:0000813)1.29080491
84Absent eyelashes (HP:0000561)1.28508885
85Limb-girdle muscle weakness (HP:0003325)1.27690818
86Congenital malformation of the right heart (HP:0011723)1.27419965
87Double outlet right ventricle (HP:0001719)1.27419965
88Pterygium (HP:0001059)1.27141720
89Insidious onset (HP:0003587)1.27133054
90Termporal pattern (HP:0011008)1.27133054
91Pachygyria (HP:0001302)1.26896679
92Failure to thrive in infancy (HP:0001531)1.26695649
93Midline defect of the nose (HP:0004122)1.26659638
94Aplasia/Hypoplasia of the sternum (HP:0006714)1.25543812
95Optic nerve hypoplasia (HP:0000609)1.25217076
96Torticollis (HP:0000473)1.24855198
97Rimmed vacuoles (HP:0003805)1.23412782
98Cutaneous syndactyly (HP:0012725)1.22685981
99Arnold-Chiari malformation (HP:0002308)1.22614973
100Meningocele (HP:0002435)1.22421131

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.48235285
2CASK2.28511055
3BCR2.26011627
4TRIM282.20920047
5LATS22.12551868
6MAP2K72.08228583
7EPHA42.07700126
8EPHB22.03259120
9WNK31.91036551
10NTRK11.87732024
11MAP3K41.75589082
12PRKD31.75478205
13LIMK11.70140902
14LATS11.67395716
15SRPK11.62809649
16TYRO31.57682660
17DYRK21.56678707
18CSNK1G31.55068789
19MINK11.52150093
20CSNK1A1L1.50864663
21EPHA21.41449623
22PAK61.41388680
23PDGFRA1.34698846
24CSNK1G21.30187489
25NTRK31.28463311
26STK38L1.26054705
27CSNK1G11.25476851
28TESK11.22458969
29STK161.21915943
30NTRK21.20914640
31PHKG21.15995887
32PHKG11.15995887
33MAP3K91.10729802
34ARAF1.10001554
35BUB11.09829604
36MET1.08372832
37ICK1.07754596
38PTK21.06226025
39LMTK21.04868078
40DYRK1B1.01837235
41PLK30.99192466
42ERBB30.97568321
43MYLK0.93967314
44CDK140.93430599
45PLK20.91299810
46PRKCG0.89672904
47CLK10.89049239
48PINK10.88577791
49UHMK10.87822395
50NEK10.87346564
51STK30.87189600
52CDK180.86153503
53ERBB40.84291087
54PAK30.82352072
55STK380.81351914
56FGFR20.81129558
57CDK150.80632881
58VRK20.80061585
59TNIK0.79941676
60BRSK10.79273747
61WEE10.77904112
62CDK11A0.75763046
63EIF2AK10.74606666
64BCKDK0.74594473
65KSR10.74036480
66SGK4940.73699631
67SGK2230.73699631
68TSSK60.72303832
69CDK80.71673596
70TTK0.69925606
71EIF2AK30.67868457
72CDK50.67233105
73DYRK30.65584770
74MAPK130.63602767
75RIPK10.62403237
76WNK40.60167910
77EEF2K0.59324787
78PAK40.56318518
79BMPR1B0.56268831
80DMPK0.53234922
81ROCK20.52497084
82PLK10.52298232
83BRAF0.52269294
84PAK20.52160491
85PNCK0.51176751
86DYRK1A0.50594437
87AKT20.48124113
88CSNK1E0.47472574
89PBK0.47405939
90CAMK2B0.46397322
91ABL20.43782222
92ILK0.42939724
93PRKCE0.42052833
94CSNK1A10.41942024
95CAMK2A0.41722727
96PKN10.40120000
97PKN20.39925947
98MAP2K40.39805470
99CHEK20.39513750
100CAMK2G0.39506527

Predicted pathways (KEGG)

RankGene SetZ-score
1Steroid biosynthesis_Homo sapiens_hsa001002.24963269
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.96805939
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.79452243
4Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.61819429
5Hippo signaling pathway_Homo sapiens_hsa043901.61015935
6Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.59602631
7Synaptic vesicle cycle_Homo sapiens_hsa047211.54326895
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.54136221
9Sulfur relay system_Homo sapiens_hsa041221.49948830
10Biosynthesis of amino acids_Homo sapiens_hsa012301.49838699
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.49324828
12Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.48999850
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.48844166
14Axon guidance_Homo sapiens_hsa043601.38285116
15Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.37558326
16Nicotine addiction_Homo sapiens_hsa050331.36730660
17Hedgehog signaling pathway_Homo sapiens_hsa043401.31749038
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.31648161
19Vibrio cholerae infection_Homo sapiens_hsa051101.31593355
20Basal cell carcinoma_Homo sapiens_hsa052171.25673583
21Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.24198583
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.21896617
23Arginine and proline metabolism_Homo sapiens_hsa003301.20705258
24GABAergic synapse_Homo sapiens_hsa047271.18260128
25Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.13757475
26Fatty acid elongation_Homo sapiens_hsa000621.10039193
27Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.07924108
28Pyruvate metabolism_Homo sapiens_hsa006201.06840913
29Vitamin B6 metabolism_Homo sapiens_hsa007501.06281220
30Tight junction_Homo sapiens_hsa045301.04586488
31Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.03565215
32Adherens junction_Homo sapiens_hsa045201.03304878
33Dopaminergic synapse_Homo sapiens_hsa047281.02933305
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.01298944
35Wnt signaling pathway_Homo sapiens_hsa043100.98209827
36Cocaine addiction_Homo sapiens_hsa050300.95153438
37Cardiac muscle contraction_Homo sapiens_hsa042600.94573962
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.93504605
39Carbon metabolism_Homo sapiens_hsa012000.93093570
40Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91421369
41Butanoate metabolism_Homo sapiens_hsa006500.91102830
42Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.89758126
43Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.89614909
44Gap junction_Homo sapiens_hsa045400.89172050
45Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.89131367
46Melanogenesis_Homo sapiens_hsa049160.88637796
47ECM-receptor interaction_Homo sapiens_hsa045120.88157174
48Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.87332431
49Glutamatergic synapse_Homo sapiens_hsa047240.87281909
50Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.86041927
51Arginine biosynthesis_Homo sapiens_hsa002200.82824810
52Folate biosynthesis_Homo sapiens_hsa007900.81897098
53Circadian rhythm_Homo sapiens_hsa047100.77935148
54Cyanoamino acid metabolism_Homo sapiens_hsa004600.76517645
55Propanoate metabolism_Homo sapiens_hsa006400.76309068
56Dilated cardiomyopathy_Homo sapiens_hsa054140.73572987
57Fatty acid metabolism_Homo sapiens_hsa012120.73109001
58Phenylalanine metabolism_Homo sapiens_hsa003600.72322999
59Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.71196690
60beta-Alanine metabolism_Homo sapiens_hsa004100.70571173
61Amphetamine addiction_Homo sapiens_hsa050310.69969833
62Basal transcription factors_Homo sapiens_hsa030220.68301419
63Protein export_Homo sapiens_hsa030600.66951642
64Insulin secretion_Homo sapiens_hsa049110.66240327
65Circadian entrainment_Homo sapiens_hsa047130.65621936
66Oocyte meiosis_Homo sapiens_hsa041140.64967297
67Sulfur metabolism_Homo sapiens_hsa009200.63071694
68Selenocompound metabolism_Homo sapiens_hsa004500.62993094
69Fatty acid degradation_Homo sapiens_hsa000710.62947261
70AMPK signaling pathway_Homo sapiens_hsa041520.60382139
71Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.58952789
72Parkinsons disease_Homo sapiens_hsa050120.57536810
73Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.56270427
74Morphine addiction_Homo sapiens_hsa050320.56235284
75Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.56123698
76Huntingtons disease_Homo sapiens_hsa050160.56116375
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54542647
78Starch and sucrose metabolism_Homo sapiens_hsa005000.54452256
79Fat digestion and absorption_Homo sapiens_hsa049750.53896963
80Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53062742
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.52532538
82Bile secretion_Homo sapiens_hsa049760.52369111
83mRNA surveillance pathway_Homo sapiens_hsa030150.52354845
84Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50411213
85Protein digestion and absorption_Homo sapiens_hsa049740.49662353
86Glucagon signaling pathway_Homo sapiens_hsa049220.49422451
87TGF-beta signaling pathway_Homo sapiens_hsa043500.48898551
88Collecting duct acid secretion_Homo sapiens_hsa049660.48753330
89Fructose and mannose metabolism_Homo sapiens_hsa000510.47370237
90Galactose metabolism_Homo sapiens_hsa000520.47297274
91Serotonergic synapse_Homo sapiens_hsa047260.47119347
92Central carbon metabolism in cancer_Homo sapiens_hsa052300.46919789
93Long-term depression_Homo sapiens_hsa047300.46904362
94Oxidative phosphorylation_Homo sapiens_hsa001900.45976830
95Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.45774944
96Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.45192218
97RNA polymerase_Homo sapiens_hsa030200.45143889
98Cholinergic synapse_Homo sapiens_hsa047250.43553242
99Alzheimers disease_Homo sapiens_hsa050100.42932641
100Metabolic pathways_Homo sapiens_hsa011000.42301736

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »