Rank | Gene Set | Z-score |
---|---|---|
1 | cilium movement (GO:0003341) | 8.78235329 |
2 | motile cilium assembly (GO:0044458) | 8.51596327 |
3 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 7.54177398 |
4 | epithelial cilium movement (GO:0003351) | 7.21294493 |
5 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 6.36399709 |
6 | axoneme assembly (GO:0035082) | 5.84942263 |
7 | synaptic vesicle maturation (GO:0016188) | 5.69028283 |
8 | glutamate secretion (GO:0014047) | 5.47731813 |
9 | left/right pattern formation (GO:0060972) | 5.25761004 |
10 | synaptic vesicle exocytosis (GO:0016079) | 5.05782034 |
11 | primary alcohol catabolic process (GO:0034310) | 4.78563099 |
12 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.78528987 |
13 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.64035609 |
14 | vitamin transmembrane transport (GO:0035461) | 4.34949075 |
15 | microtubule bundle formation (GO:0001578) | 4.24204704 |
16 | regulation of cilium movement (GO:0003352) | 4.15591170 |
17 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 4.14813911 |
18 | cellular potassium ion homeostasis (GO:0030007) | 4.14802937 |
19 | ventricular system development (GO:0021591) | 4.10116121 |
20 | neurotransmitter secretion (GO:0007269) | 4.09191818 |
21 | ethanol metabolic process (GO:0006067) | 4.05242255 |
22 | lung epithelium development (GO:0060428) | 3.94098591 |
23 | cerebellar granule cell differentiation (GO:0021707) | 3.90996925 |
24 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.89438673 |
25 | sodium ion export (GO:0071436) | 3.88556916 |
26 | regulation of synaptic vesicle transport (GO:1902803) | 3.85406295 |
27 | one-carbon compound transport (GO:0019755) | 3.81743178 |
28 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.77945669 |
29 | diterpenoid biosynthetic process (GO:0016102) | 3.74536356 |
30 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.64538452 |
31 | regulation of ARF protein signal transduction (GO:0032012) | 3.64276704 |
32 | negative regulation of inclusion body assembly (GO:0090084) | 3.61525422 |
33 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.59829811 |
34 | L-amino acid import (GO:0043092) | 3.55414895 |
35 | left/right axis specification (GO:0070986) | 3.54841686 |
36 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.53631833 |
37 | vocalization behavior (GO:0071625) | 3.52138996 |
38 | sperm capacitation (GO:0048240) | 3.44473285 |
39 | potassium ion homeostasis (GO:0055075) | 3.43024550 |
40 | locomotory exploration behavior (GO:0035641) | 3.35565115 |
41 | protein localization to cilium (GO:0061512) | 3.31196318 |
42 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.30972336 |
43 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.27129293 |
44 | positive regulation of synapse maturation (GO:0090129) | 3.25983381 |
45 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.22870046 |
46 | neurotransmitter transport (GO:0006836) | 3.20282312 |
47 | ethanol oxidation (GO:0006069) | 3.20214466 |
48 | regulation of neurotransmitter levels (GO:0001505) | 3.16217573 |
49 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.14483682 |
50 | regulation of interleukin-5 production (GO:0032674) | 3.10029235 |
51 | regulation of microtubule-based movement (GO:0060632) | 3.09673016 |
52 | amino acid import (GO:0043090) | 3.08901027 |
53 | microtubule-based movement (GO:0007018) | 3.07596096 |
54 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.04149854 |
55 | cilium organization (GO:0044782) | 3.03591549 |
56 | regulation of interleukin-13 production (GO:0032656) | 3.03006500 |
57 | apical protein localization (GO:0045176) | 3.02410805 |
58 | regulation of synaptic plasticity (GO:0048167) | 3.01266782 |
59 | intraciliary transport (GO:0042073) | 3.01050742 |
60 | negative regulation of B cell mediated immunity (GO:0002713) | 3.00427913 |
61 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.00427913 |
62 | cilium assembly (GO:0042384) | 2.97410688 |
63 | exploration behavior (GO:0035640) | 2.95498947 |
64 | sodium ion homeostasis (GO:0055078) | 2.89313665 |
65 | synaptic transmission, glutamatergic (GO:0035249) | 2.88078483 |
66 | positive regulation of membrane potential (GO:0045838) | 2.79640061 |
67 | cellular sodium ion homeostasis (GO:0006883) | 2.78855418 |
68 | neuronal ion channel clustering (GO:0045161) | 2.77618051 |
69 | regulation of vesicle fusion (GO:0031338) | 2.76807352 |
70 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.76580909 |
71 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.71174271 |
72 | regulation of germinal center formation (GO:0002634) | 2.70337158 |
73 | establishment of apical/basal cell polarity (GO:0035089) | 2.68774750 |
74 | chemosensory behavior (GO:0007635) | 2.68471723 |
75 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.68220825 |
76 | positive regulation of neurotransmitter secretion (GO:0001956) | 2.66449812 |
77 | regulation of neurotransmitter secretion (GO:0046928) | 2.65170110 |
78 | regulation of cell communication by electrical coupling (GO:0010649) | 2.63949837 |
79 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 2.63472911 |
80 | cytoplasmic microtubule organization (GO:0031122) | 2.59783625 |
81 | positive regulation of neurotransmitter transport (GO:0051590) | 2.59670565 |
82 | potassium ion import (GO:0010107) | 2.58152137 |
83 | response to xenobiotic stimulus (GO:0009410) | 2.57744097 |
84 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.57214420 |
85 | tolerance induction (GO:0002507) | 2.54979235 |
86 | detection of calcium ion (GO:0005513) | 2.53775225 |
87 | cellular component assembly involved in morphogenesis (GO:0010927) | 2.52836627 |
88 | neuromuscular process controlling balance (GO:0050885) | 2.52366525 |
89 | positive regulation of vesicle fusion (GO:0031340) | 2.52216285 |
90 | neuron-neuron synaptic transmission (GO:0007270) | 2.51585028 |
91 | regulation of synapse maturation (GO:0090128) | 2.51276074 |
92 | regulation of synapse structural plasticity (GO:0051823) | 2.51256771 |
93 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.51143875 |
94 | glomerular epithelial cell development (GO:0072310) | 2.50438114 |
95 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 2.49555070 |
96 | dendritic spine morphogenesis (GO:0060997) | 2.48439763 |
97 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.47912067 |
98 | dendritic spine organization (GO:0097061) | 2.47820607 |
99 | axonemal dynein complex assembly (GO:0070286) | 12.3987897 |
100 | cilium or flagellum-dependent cell motility (GO:0001539) | 10.1965121 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DROSHA_22980978_ChIP-Seq_HELA_Human | 3.78349379 |
2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.17991441 |
3 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.47633039 |
4 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 2.33558109 |
5 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.21048750 |
6 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.20304326 |
7 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.17240584 |
8 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.16548880 |
9 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.08514720 |
10 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.06643444 |
11 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.00700053 |
12 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.99236032 |
13 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.96527110 |
14 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.93689392 |
15 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.93609355 |
16 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.92770761 |
17 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.89421786 |
18 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.88964992 |
19 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.87949009 |
20 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.85449934 |
21 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.80052357 |
22 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.65556088 |
23 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.65165373 |
24 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.63763899 |
25 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.57321940 |
26 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.57321940 |
27 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.57089232 |
28 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.56419870 |
29 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.55456344 |
30 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.55262065 |
31 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.55038895 |
32 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.52773781 |
33 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.51593808 |
34 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.48489210 |
35 | KDM2B_26808549_Chip-Seq_K562_Human | 1.45507539 |
36 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.43834857 |
37 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.42841240 |
38 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.41435657 |
39 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.40933571 |
40 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.40503968 |
41 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.38242356 |
42 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.37879917 |
43 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.36738320 |
44 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.36133183 |
45 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.31255266 |
46 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.28260289 |
47 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.28160947 |
48 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.27345774 |
49 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.27159864 |
50 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.24864724 |
51 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.24612675 |
52 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.21768797 |
53 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.19848488 |
54 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.19327913 |
55 | P68_20966046_ChIP-Seq_HELA_Human | 1.17326220 |
56 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.16077089 |
57 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.15359239 |
58 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.14706438 |
59 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.14066589 |
60 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.13583400 |
61 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.12041904 |
62 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.11551205 |
63 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.10532736 |
64 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.09141144 |
65 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.07853175 |
66 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.07208459 |
67 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.06922266 |
68 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.03843617 |
69 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.03822217 |
70 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.02709340 |
71 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.02654775 |
72 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.95873371 |
73 | AR_19668381_ChIP-Seq_PC3_Human | 0.95634667 |
74 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95022159 |
75 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.95008147 |
76 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.94277834 |
77 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.93960844 |
78 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.93047345 |
79 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.92233503 |
80 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.92208136 |
81 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90430319 |
82 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.89009530 |
83 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.88451578 |
84 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.88234135 |
85 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.88210904 |
86 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.87145545 |
87 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.87105157 |
88 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.86770087 |
89 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.86700004 |
90 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.84867335 |
91 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.84001634 |
92 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.83260127 |
93 | GATA1_19941826_ChIP-Seq_K562_Human | 0.83123827 |
94 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.82802953 |
95 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.82516573 |
96 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.82472403 |
97 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.81241516 |
98 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.81029916 |
99 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.80943891 |
100 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.80448526 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 5.70508106 |
2 | MP0009780_abnormal_chondrocyte_physiolo | 4.41879628 |
3 | MP0003880_abnormal_central_pattern | 3.92876059 |
4 | MP0004270_analgesia | 3.73357264 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 3.33377281 |
6 | MP0003635_abnormal_synaptic_transmissio | 3.12960475 |
7 | MP0002064_seizures | 3.09374846 |
8 | MP0002653_abnormal_ependyma_morphology | 2.80268704 |
9 | MP0002734_abnormal_mechanical_nocicepti | 2.79821456 |
10 | MP0009745_abnormal_behavioral_response | 2.79649593 |
11 | MP0009046_muscle_twitch | 2.71251697 |
12 | MP0001984_abnormal_olfaction | 2.58524858 |
13 | MP0002063_abnormal_learning/memory/cond | 2.53948619 |
14 | MP0005423_abnormal_somatic_nervous | 2.43704446 |
15 | MP0010234_abnormal_vibrissa_follicle | 2.38633279 |
16 | MP0001486_abnormal_startle_reflex | 2.38503105 |
17 | MP0004043_abnormal_pH_regulation | 2.37174973 |
18 | MP0002272_abnormal_nervous_system | 2.34746459 |
19 | MP0003879_abnormal_hair_cell | 2.26783198 |
20 | MP0002572_abnormal_emotion/affect_behav | 2.22230042 |
21 | MP0001501_abnormal_sleep_pattern | 2.15831042 |
22 | MP0005623_abnormal_meninges_morphology | 1.97696692 |
23 | MP0001968_abnormal_touch/_nociception | 1.97629155 |
24 | MP0003329_amyloid_beta_deposits | 1.95751974 |
25 | MP0002735_abnormal_chemical_nociception | 1.94965782 |
26 | MP0008569_lethality_at_weaning | 1.71772263 |
27 | MP0001970_abnormal_pain_threshold | 1.70760865 |
28 | MP0002132_abnormal_respiratory_system | 1.67503908 |
29 | MP0000566_synostosis | 1.67051868 |
30 | MP0002909_abnormal_adrenal_gland | 1.64324001 |
31 | MP0001765_abnormal_ion_homeostasis | 1.58832339 |
32 | MP0003075_altered_response_to | 1.58517669 |
33 | MP0001346_abnormal_lacrimal_gland | 1.55671583 |
34 | MP0001502_abnormal_circadian_rhythm | 1.50612143 |
35 | MP0003633_abnormal_nervous_system | 1.47132373 |
36 | MP0005646_abnormal_pituitary_gland | 1.45320680 |
37 | MP0004133_heterotaxia | 1.39810263 |
38 | MP0003690_abnormal_glial_cell | 1.37466071 |
39 | MP0010678_abnormal_skin_adnexa | 1.31386421 |
40 | MP0004885_abnormal_endolymph | 1.26572923 |
41 | MP0002733_abnormal_thermal_nociception | 1.25562102 |
42 | MP0004811_abnormal_neuron_physiology | 1.22648324 |
43 | MP0002557_abnormal_social/conspecific_i | 1.22430903 |
44 | MP0002277_abnormal_respiratory_mucosa | 1.21869252 |
45 | MP0002736_abnormal_nociception_after | 1.21198630 |
46 | MP0002067_abnormal_sensory_capabilities | 1.20652803 |
47 | MP0005409_darkened_coat_color | 1.19612281 |
48 | MP0003631_nervous_system_phenotype | 1.18501765 |
49 | MP0000920_abnormal_myelination | 1.17715088 |
50 | MP0002066_abnormal_motor_capabilities/c | 1.17714689 |
51 | MP0001485_abnormal_pinna_reflex | 1.16262648 |
52 | MP0001440_abnormal_grooming_behavior | 1.14095341 |
53 | MP0004019_abnormal_vitamin_homeostasis | 1.13735868 |
54 | MP0000383_abnormal_hair_follicle | 1.12532778 |
55 | MP0003634_abnormal_glial_cell | 1.11881802 |
56 | MP0003878_abnormal_ear_physiology | 1.10736016 |
57 | MP0005377_hearing/vestibular/ear_phenot | 1.10736016 |
58 | MP0002229_neurodegeneration | 1.10653643 |
59 | MP0000678_abnormal_parathyroid_gland | 1.06857825 |
60 | MP0002882_abnormal_neuron_morphology | 1.04842043 |
61 | MP0002822_catalepsy | 0.96999139 |
62 | MP0002168_other_aberrant_phenotype | 0.95740621 |
63 | MP0008789_abnormal_olfactory_epithelium | 0.95559555 |
64 | MP0005499_abnormal_olfactory_system | 0.93349114 |
65 | MP0005394_taste/olfaction_phenotype | 0.93349114 |
66 | MP0000955_abnormal_spinal_cord | 0.92488258 |
67 | MP0005165_increased_susceptibility_to | 0.90653825 |
68 | MP0005166_decreased_susceptibility_to | 0.90462731 |
69 | MP0002249_abnormal_larynx_morphology | 0.89646268 |
70 | MP0001963_abnormal_hearing_physiology | 0.88832128 |
71 | MP0003183_abnormal_peptide_metabolism | 0.88025718 |
72 | MP0003123_paternal_imprinting | 0.87875139 |
73 | MP0001905_abnormal_dopamine_level | 0.86935493 |
74 | MP0003045_fibrosis | 0.85505005 |
75 | MP0008874_decreased_physiological_sensi | 0.85278664 |
76 | MP0003172_abnormal_lysosome_physiology | 0.82615055 |
77 | MP0000681_abnormal_thyroid_gland | 0.81936808 |
78 | MP0004924_abnormal_behavior | 0.80149802 |
79 | MP0005386_behavior/neurological_phenoty | 0.80149802 |
80 | MP0002876_abnormal_thyroid_physiology | 0.79237167 |
81 | MP0003632_abnormal_nervous_system | 0.78318625 |
82 | MP0003787_abnormal_imprinting | 0.78205941 |
83 | MP0000604_amyloidosis | 0.78193769 |
84 | MP0008872_abnormal_physiological_respon | 0.77510940 |
85 | MP0002638_abnormal_pupillary_reflex | 0.76976736 |
86 | MP0001177_atelectasis | 0.75613966 |
87 | MP0002152_abnormal_brain_morphology | 0.72205515 |
88 | MP0002160_abnormal_reproductive_system | 0.72022701 |
89 | MP0005636_abnormal_mineral_homeostasis | 0.71352737 |
90 | MP0001664_abnormal_digestion | 0.71210266 |
91 | MP0001849_ear_inflammation | 0.69337941 |
92 | MP0004742_abnormal_vestibular_system | 0.65525833 |
93 | MP0001188_hyperpigmentation | 0.63977944 |
94 | MP0005535_abnormal_body_temperature | 0.58581094 |
95 | MP0005551_abnormal_eye_electrophysiolog | 0.58129704 |
96 | MP0005388_respiratory_system_phenotype | 0.58016014 |
97 | MP0002133_abnormal_respiratory_system | 0.58016014 |
98 | MP0002069_abnormal_eating/drinking_beha | 0.57798334 |
99 | MP0003303_peritoneal_inflammation | 0.57042849 |
100 | MP0002184_abnormal_innervation | 0.55247267 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormal respiratory epithelium morphology (HP:0012253) | 9.61841029 |
2 | Abnormal respiratory motile cilium morphology (HP:0005938) | 9.61841029 |
3 | Abnormal respiratory motile cilium physiology (HP:0012261) | 9.41071683 |
4 | Absent/shortened dynein arms (HP:0200106) | 9.37491173 |
5 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 9.37491173 |
6 | Abnormal ciliary motility (HP:0012262) | 9.21802003 |
7 | Rhinitis (HP:0012384) | 8.71754955 |
8 | Chronic bronchitis (HP:0004469) | 6.89781080 |
9 | Bronchiectasis (HP:0002110) | 6.33014721 |
10 | Nasal polyposis (HP:0100582) | 6.04299811 |
11 | Abnormality of the nasal mucosa (HP:0000433) | 5.13732136 |
12 | Infertility (HP:0000789) | 3.76206569 |
13 | Male infertility (HP:0003251) | 3.65693095 |
14 | Bronchitis (HP:0012387) | 3.64547793 |
15 | Recurrent sinusitis (HP:0011108) | 3.61834264 |
16 | Myokymia (HP:0002411) | 3.60218673 |
17 | Recurrent otitis media (HP:0000403) | 3.46410348 |
18 | Chronic sinusitis (HP:0011109) | 3.30093958 |
19 | Hyperactive renin-angiotensin system (HP:0000841) | 3.24006300 |
20 | Atelectasis (HP:0100750) | 3.02800672 |
21 | Obstructive sleep apnea (HP:0002870) | 2.99129509 |
22 | Focal motor seizures (HP:0011153) | 2.96505399 |
23 | Occipital encephalocele (HP:0002085) | 2.75811871 |
24 | Focal seizures (HP:0007359) | 2.58635272 |
25 | Chronic otitis media (HP:0000389) | 2.53214399 |
26 | Epileptic encephalopathy (HP:0200134) | 2.49649216 |
27 | Ankle clonus (HP:0011448) | 2.45400248 |
28 | Supranuclear gaze palsy (HP:0000605) | 2.33832303 |
29 | Cystic liver disease (HP:0006706) | 2.27066331 |
30 | Action tremor (HP:0002345) | 2.24799582 |
31 | Pancreatic fibrosis (HP:0100732) | 2.18491369 |
32 | Febrile seizures (HP:0002373) | 2.16881572 |
33 | Torticollis (HP:0000473) | 2.16523522 |
34 | True hermaphroditism (HP:0010459) | 2.16377558 |
35 | Renal salt wasting (HP:0000127) | 2.12515584 |
36 | Papilledema (HP:0001085) | 2.10284726 |
37 | Bell-shaped thorax (HP:0001591) | 2.07482450 |
38 | Ventricular fibrillation (HP:0001663) | 2.03630960 |
39 | Neurofibrillary tangles (HP:0002185) | 2.00087783 |
40 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 10.8547474 |
41 | Visual hallucinations (HP:0002367) | 1.99746672 |
42 | Hand muscle atrophy (HP:0009130) | 1.94532349 |
43 | Hyperaldosteronism (HP:0000859) | 1.93280450 |
44 | Atonic seizures (HP:0010819) | 1.91535833 |
45 | Abnormality of renin-angiotensin system (HP:0000847) | 1.86927745 |
46 | Decreased circulating renin level (HP:0003351) | 1.85785384 |
47 | Hyperkalemia (HP:0002153) | 1.84630981 |
48 | Diplopia (HP:0000651) | 1.82103254 |
49 | Abnormality of binocular vision (HP:0011514) | 1.82103254 |
50 | Nephronophthisis (HP:0000090) | 1.81112393 |
51 | Depression (HP:0000716) | 1.77521912 |
52 | Postural instability (HP:0002172) | 1.76582883 |
53 | Sleep apnea (HP:0010535) | 1.75138250 |
54 | Upper limb amyotrophy (HP:0009129) | 1.74429153 |
55 | Distal upper limb amyotrophy (HP:0007149) | 1.74429153 |
56 | Focal dystonia (HP:0004373) | 1.72837385 |
57 | Fetal akinesia sequence (HP:0001989) | 1.68626726 |
58 | Neuronal loss in central nervous system (HP:0002529) | 1.66683024 |
59 | Craniofacial dystonia (HP:0012179) | 1.64467259 |
60 | Tubulointerstitial nephritis (HP:0001970) | 1.64386278 |
61 | Molar tooth sign on MRI (HP:0002419) | 1.64268453 |
62 | Abnormality of midbrain morphology (HP:0002418) | 1.64268453 |
63 | Spastic gait (HP:0002064) | 1.62617422 |
64 | Abnormality of chloride homeostasis (HP:0011422) | 1.61282724 |
65 | Absent frontal sinuses (HP:0002688) | 1.60247498 |
66 | Annular pancreas (HP:0001734) | 1.58486592 |
67 | Spinal cord compression (HP:0002176) | 1.53162376 |
68 | Hypokalemic alkalosis (HP:0001949) | 1.52717993 |
69 | Postaxial foot polydactyly (HP:0001830) | 1.51837590 |
70 | Urinary urgency (HP:0000012) | 1.51019546 |
71 | Truncal ataxia (HP:0002078) | 1.48926305 |
72 | Cerebral inclusion bodies (HP:0100314) | 1.48836539 |
73 | Stridor (HP:0010307) | 1.48560970 |
74 | Generalized tonic-clonic seizures (HP:0002069) | 1.47919206 |
75 | Pancreatic cysts (HP:0001737) | 1.47330237 |
76 | Intention tremor (HP:0002080) | 1.46942063 |
77 | Tetraplegia (HP:0002445) | 1.46501987 |
78 | Abnormality of permanent molar morphology (HP:0011071) | 1.45916092 |
79 | Abnormality of the dental root (HP:0006486) | 1.45916092 |
80 | Taurodontia (HP:0000679) | 1.45916092 |
81 | Absent speech (HP:0001344) | 1.45075282 |
82 | Dysmetria (HP:0001310) | 1.44846816 |
83 | Glucose intolerance (HP:0000833) | 1.43319090 |
84 | Nephropathy (HP:0000112) | 1.42935059 |
85 | Akinesia (HP:0002304) | 1.42676420 |
86 | Gait imbalance (HP:0002141) | 1.41915841 |
87 | Recurrent bronchitis (HP:0002837) | 1.40949908 |
88 | Absence seizures (HP:0002121) | 1.40376112 |
89 | Chronic hepatic failure (HP:0100626) | 1.39997357 |
90 | Progressive cerebellar ataxia (HP:0002073) | 1.39470360 |
91 | Adrenal overactivity (HP:0002717) | 1.39346892 |
92 | Abnormality of the renal medulla (HP:0100957) | 1.35175151 |
93 | Abnormal eating behavior (HP:0100738) | 1.33942524 |
94 | Abnormality of molar (HP:0011077) | 1.32594000 |
95 | Abnormality of molar morphology (HP:0011070) | 1.32594000 |
96 | Distal lower limb muscle weakness (HP:0009053) | 1.31862243 |
97 | Dialeptic seizures (HP:0011146) | 1.31576534 |
98 | Asplenia (HP:0001746) | 1.30366185 |
99 | Lower limb asymmetry (HP:0100559) | 1.29442837 |
100 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.29263593 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAPK15 | 5.96991656 |
2 | EPHA4 | 4.82759558 |
3 | EPHA2 | 3.28921219 |
4 | NTRK3 | 3.10168048 |
5 | PAK6 | 2.90623416 |
6 | DAPK2 | 2.71446800 |
7 | CAMKK1 | 2.46644186 |
8 | RIPK4 | 2.37832396 |
9 | MST4 | 2.34709738 |
10 | MAP3K2 | 2.28006869 |
11 | PRKD3 | 1.96486508 |
12 | RIPK1 | 1.96302733 |
13 | UHMK1 | 1.91963755 |
14 | MAP3K9 | 1.76804569 |
15 | NEK6 | 1.69762381 |
16 | MINK1 | 1.54977388 |
17 | NTRK1 | 1.45949919 |
18 | MARK2 | 1.44210464 |
19 | STK38 | 1.42502284 |
20 | TESK1 | 1.30100088 |
21 | ARAF | 1.28620679 |
22 | MARK1 | 1.22817088 |
23 | MAPKAPK3 | 1.20414517 |
24 | KSR2 | 1.19432227 |
25 | MST1R | 1.18770698 |
26 | NME1 | 1.18134714 |
27 | SMG1 | 1.14121760 |
28 | NTRK2 | 1.12624853 |
29 | LATS2 | 1.11659763 |
30 | DAPK1 | 1.11443274 |
31 | CDK5 | 1.09019623 |
32 | GRK5 | 1.07293474 |
33 | MAP3K12 | 1.04143681 |
34 | TRIB3 | 1.03000352 |
35 | BMPR2 | 1.02640924 |
36 | CAMK1 | 0.99863654 |
37 | PTK2B | 0.98656145 |
38 | SGK223 | 0.93308053 |
39 | SGK494 | 0.93308053 |
40 | PRKCH | 0.92702763 |
41 | CAMK2G | 0.91113328 |
42 | PDPK1 | 0.90600589 |
43 | LMTK2 | 0.90399733 |
44 | CDK19 | 0.86107762 |
45 | OXSR1 | 0.85295182 |
46 | MAP3K13 | 0.82950727 |
47 | SGK1 | 0.82176981 |
48 | EEF2K | 0.80329996 |
49 | CAMK2B | 0.79864277 |
50 | PHKG2 | 0.76928386 |
51 | PHKG1 | 0.76928386 |
52 | PDK1 | 0.75236950 |
53 | SGK3 | 0.74801127 |
54 | PLK2 | 0.74230474 |
55 | STK24 | 0.73789373 |
56 | STK11 | 0.73054794 |
57 | SGK2 | 0.72659799 |
58 | SIK2 | 0.72078447 |
59 | PAK3 | 0.71625709 |
60 | PRPF4B | 0.71415798 |
61 | CAMK2A | 0.71408914 |
62 | MAP3K3 | 0.70636428 |
63 | MAP3K7 | 0.69653532 |
64 | ERBB2 | 0.67066311 |
65 | PRKCI | 0.65647503 |
66 | ICK | 0.65426605 |
67 | CAMKK2 | 0.64531359 |
68 | MAP3K1 | 0.64050166 |
69 | DYRK1A | 0.62783887 |
70 | MAPK12 | 0.62342138 |
71 | PRKCG | 0.59868828 |
72 | ALK | 0.59484111 |
73 | MAP3K11 | 0.58428453 |
74 | PNCK | 0.58246583 |
75 | EPHB1 | 0.58201458 |
76 | MAPK13 | 0.57226417 |
77 | MAPK10 | 0.55759547 |
78 | RET | 0.51367678 |
79 | PINK1 | 0.50788375 |
80 | ROCK2 | 0.50066782 |
81 | FER | 0.47053295 |
82 | CDK15 | 0.45622772 |
83 | MET | 0.44647603 |
84 | MAP2K4 | 0.43950739 |
85 | ROCK1 | 0.43531529 |
86 | FGFR3 | 0.43177732 |
87 | FYN | 0.43076707 |
88 | PRKCZ | 0.42625518 |
89 | MAP2K6 | 0.42405352 |
90 | CDK18 | 0.42060316 |
91 | PTK2 | 0.41041517 |
92 | RPS6KA3 | 0.41010488 |
93 | CASK | 0.40920384 |
94 | PRKG2 | 0.39752303 |
95 | PRKCA | 0.38954490 |
96 | CDC42BPA | 0.38854781 |
97 | CDK11A | 0.37871042 |
98 | TRPM7 | 0.37760860 |
99 | LRRK2 | 0.37103477 |
100 | TNK2 | 0.36346521 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.27144497 |
2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.95109513 |
3 | Histidine metabolism_Homo sapiens_hsa00340 | 2.70581757 |
4 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 2.64001442 |
5 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.38141693 |
6 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 2.31355516 |
7 | Long-term potentiation_Homo sapiens_hsa04720 | 2.24393022 |
8 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.13102508 |
9 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 2.12952690 |
10 | Insulin secretion_Homo sapiens_hsa04911 | 2.08063780 |
11 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 2.06427268 |
12 | Circadian entrainment_Homo sapiens_hsa04713 | 1.93998848 |
13 | Salivary secretion_Homo sapiens_hsa04970 | 1.93484696 |
14 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.80060720 |
15 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.76730220 |
16 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.70804031 |
17 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.68996720 |
18 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.66895340 |
19 | Cocaine addiction_Homo sapiens_hsa05030 | 1.65915744 |
20 | GABAergic synapse_Homo sapiens_hsa04727 | 1.64734861 |
21 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.61778186 |
22 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.60780410 |
23 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.58686827 |
24 | Morphine addiction_Homo sapiens_hsa05032 | 1.53295804 |
25 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.52838626 |
26 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.51921834 |
27 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.50253053 |
28 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.28843296 |
29 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.26672633 |
30 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.26410638 |
31 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.26187265 |
32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.22236558 |
33 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.19286120 |
34 | Renin secretion_Homo sapiens_hsa04924 | 1.19049834 |
35 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.18410577 |
36 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.17312074 |
37 | Taste transduction_Homo sapiens_hsa04742 | 1.13541281 |
38 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.12126034 |
39 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.12031091 |
40 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.03112208 |
41 | Tight junction_Homo sapiens_hsa04530 | 0.98476444 |
42 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.95587109 |
43 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.94566147 |
44 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.93794866 |
45 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.91043891 |
46 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.88816227 |
47 | Circadian rhythm_Homo sapiens_hsa04710 | 0.88245640 |
48 | Bile secretion_Homo sapiens_hsa04976 | 0.88193926 |
49 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.86835306 |
50 | Olfactory transduction_Homo sapiens_hsa04740 | 0.86801109 |
51 | Melanogenesis_Homo sapiens_hsa04916 | 0.86250584 |
52 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.80583343 |
53 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.78526826 |
54 | Glioma_Homo sapiens_hsa05214 | 0.77446331 |
55 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.77388752 |
56 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.74806008 |
57 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.73542892 |
58 | Long-term depression_Homo sapiens_hsa04730 | 0.73048585 |
59 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.71440149 |
60 | Gap junction_Homo sapiens_hsa04540 | 0.69252183 |
61 | ABC transporters_Homo sapiens_hsa02010 | 0.68024686 |
62 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.65312955 |
63 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.64886141 |
64 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.64822145 |
65 | Endocytosis_Homo sapiens_hsa04144 | 0.64001506 |
66 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.61565303 |
67 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.61356663 |
68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.60680691 |
69 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.56258735 |
70 | Axon guidance_Homo sapiens_hsa04360 | 0.56193177 |
71 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.54728343 |
72 | Mineral absorption_Homo sapiens_hsa04978 | 0.52298011 |
73 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.51954762 |
74 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.50772128 |
75 | Retinol metabolism_Homo sapiens_hsa00830 | 0.48697228 |
76 | Huntingtons disease_Homo sapiens_hsa05016 | 0.48550241 |
77 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.48464753 |
78 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.47920211 |
79 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.47853817 |
80 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46980733 |
81 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.46705021 |
82 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.46426312 |
83 | Prion diseases_Homo sapiens_hsa05020 | 0.46417805 |
84 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.45486845 |
85 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.44035371 |
86 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.43762222 |
87 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.42981533 |
88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.42790152 |
89 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.42248225 |
90 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.41905273 |
91 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.40674558 |
92 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.39516049 |
93 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.39170091 |
94 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.37908968 |
95 | Phototransduction_Homo sapiens_hsa04744 | 0.35594006 |
96 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.35238339 |
97 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.35201487 |
98 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.34865958 |
99 | Amoebiasis_Homo sapiens_hsa05146 | 0.34535239 |
100 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.33676248 |