

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 6.69863806 |
| 2 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 6.56028463 |
| 3 | negative regulation of cell killing (GO:0031342) | 6.56028463 |
| 4 | regulation of B cell receptor signaling pathway (GO:0050855) | 6.04235735 |
| 5 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.00558496 |
| 6 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.62891794 |
| 7 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.62891794 |
| 8 | modulation by symbiont of host immune response (GO:0052553) | 5.62891794 |
| 9 | positive regulation by symbiont of host defense response (GO:0052509) | 5.62891794 |
| 10 | modulation by symbiont of host defense response (GO:0052031) | 5.62891794 |
| 11 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.62891794 |
| 12 | detection of molecule of bacterial origin (GO:0032490) | 5.39154723 |
| 13 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.29828329 |
| 14 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.06830115 |
| 15 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.92797760 |
| 16 | regulation of gamma-delta T cell activation (GO:0046643) | 4.88720468 |
| 17 | response to interleukin-15 (GO:0070672) | 4.84588752 |
| 18 | negative T cell selection (GO:0043383) | 4.83328514 |
| 19 | cellular response to interleukin-15 (GO:0071350) | 4.66840521 |
| 20 | negative thymic T cell selection (GO:0045060) | 4.59584676 |
| 21 | microglial cell activation (GO:0001774) | 4.56948487 |
| 22 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.52701817 |
| 23 | macrophage activation involved in immune response (GO:0002281) | 4.46785484 |
| 24 | detection of external biotic stimulus (GO:0098581) | 4.35206674 |
| 25 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.34378078 |
| 26 | cellular extravasation (GO:0045123) | 4.33060565 |
| 27 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.33003538 |
| 28 | detection of other organism (GO:0098543) | 4.27978330 |
| 29 | positive T cell selection (GO:0043368) | 4.21680589 |
| 30 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 4.17341639 |
| 31 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.15602817 |
| 32 | negative regulation of T cell mediated immunity (GO:0002710) | 4.14599204 |
| 33 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.09116251 |
| 34 | neutrophil activation involved in immune response (GO:0002283) | 4.01980989 |
| 35 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.99123553 |
| 36 | B cell receptor signaling pathway (GO:0050853) | 3.96796025 |
| 37 | positive thymic T cell selection (GO:0045059) | 3.92994836 |
| 38 | neutrophil mediated immunity (GO:0002446) | 3.90922334 |
| 39 | response to host immune response (GO:0052572) | 3.85806528 |
| 40 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.85806528 |
| 41 | detection of biotic stimulus (GO:0009595) | 3.82082286 |
| 42 | macrophage activation (GO:0042116) | 3.80988459 |
| 43 | leukocyte aggregation (GO:0070486) | 3.76477213 |
| 44 | regulation of B cell differentiation (GO:0045577) | 3.75223623 |
| 45 | activated T cell proliferation (GO:0050798) | 3.73800308 |
| 46 | negative regulation of interleukin-12 production (GO:0032695) | 3.66699819 |
| 47 | neutrophil activation (GO:0042119) | 3.64655307 |
| 48 | detection of bacterium (GO:0016045) | 3.63180020 |
| 49 | T cell migration (GO:0072678) | 3.57038499 |
| 50 | myeloid leukocyte mediated immunity (GO:0002444) | 3.55750345 |
| 51 | dendritic cell migration (GO:0036336) | 3.53804225 |
| 52 | hepatocyte apoptotic process (GO:0097284) | 3.53784032 |
| 53 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.52875425 |
| 54 | response to host (GO:0075136) | 3.52196761 |
| 55 | response to host defenses (GO:0052200) | 3.52196761 |
| 56 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.52196761 |
| 57 | T cell selection (GO:0045058) | 3.52007383 |
| 58 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.51704297 |
| 59 | myeloid cell activation involved in immune response (GO:0002275) | 3.46282259 |
| 60 | respiratory burst (GO:0045730) | 3.45988740 |
| 61 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.44633327 |
| 62 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.42282368 |
| 63 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.39363863 |
| 64 | positive regulation of granulocyte differentiation (GO:0030854) | 3.39074590 |
| 65 | positive regulation of B cell differentiation (GO:0045579) | 3.36805662 |
| 66 | negative regulation of B cell proliferation (GO:0030889) | 3.36111625 |
| 67 | interferon-gamma production (GO:0032609) | 3.31798481 |
| 68 | dendritic cell chemotaxis (GO:0002407) | 3.29266265 |
| 69 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.27206846 |
| 70 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.26631956 |
| 71 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.24935224 |
| 72 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.24066257 |
| 73 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.23507901 |
| 74 | regulation of regulatory T cell differentiation (GO:0045589) | 3.22505906 |
| 75 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.20690809 |
| 76 | positive regulation of interferon-alpha production (GO:0032727) | 3.19214338 |
| 77 | granulocyte activation (GO:0036230) | 3.18958879 |
| 78 | response to peptidoglycan (GO:0032494) | 3.18895832 |
| 79 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.14491861 |
| 80 | thymic T cell selection (GO:0045061) | 3.13223594 |
| 81 | tolerance induction (GO:0002507) | 3.07837804 |
| 82 | negative regulation of adaptive immune response (GO:0002820) | 3.04526458 |
| 83 | histone H3-K36 demethylation (GO:0070544) | 3.03507045 |
| 84 | mast cell activation (GO:0045576) | 3.00830032 |
| 85 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.00281289 |
| 86 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.00281289 |
| 87 | leukocyte degranulation (GO:0043299) | 2.93183522 |
| 88 | regulation of interferon-alpha production (GO:0032647) | 2.92311983 |
| 89 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.91055402 |
| 90 | type I interferon signaling pathway (GO:0060337) | 2.90469530 |
| 91 | cellular response to type I interferon (GO:0071357) | 2.90469530 |
| 92 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.88675228 |
| 93 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.88668275 |
| 94 | response to type I interferon (GO:0034340) | 2.88579985 |
| 95 | regulation of tolerance induction (GO:0002643) | 2.87669584 |
| 96 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.86078646 |
| 97 | defense response to protozoan (GO:0042832) | 2.83214359 |
| 98 | regulation of necroptotic process (GO:0060544) | 2.82851694 |
| 99 | negative regulation of B cell mediated immunity (GO:0002713) | 2.79364409 |
| 100 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.79364409 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.01091024 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.12895712 |
| 3 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.08180536 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.82113373 |
| 5 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.50629490 |
| 6 | RUNX_20019798_ChIP-Seq_JUKART_Human | 3.50398806 |
| 7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.42643965 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.14396946 |
| 9 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.03267686 |
| 10 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.02942102 |
| 11 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.99763015 |
| 12 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.96541166 |
| 13 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.95299241 |
| 14 | MYB_26560356_Chip-Seq_TH2_Human | 2.88169451 |
| 15 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.82229782 |
| 16 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.77693370 |
| 17 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.48461315 |
| 18 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.42734389 |
| 19 | MYB_26560356_Chip-Seq_TH1_Human | 2.33633905 |
| 20 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.30731934 |
| 21 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.30583868 |
| 22 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.19111962 |
| 23 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.16812499 |
| 24 | GATA3_27048872_Chip-Seq_THYMUS_Human | 2.10741808 |
| 25 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.94768139 |
| 26 | SPI1_23127762_ChIP-Seq_K562_Human | 1.94206206 |
| 27 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.91540335 |
| 28 | GATA3_26560356_Chip-Seq_TH2_Human | 1.80862480 |
| 29 | MAF_26560356_Chip-Seq_TH1_Human | 1.78106861 |
| 30 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.77296135 |
| 31 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.75049734 |
| 32 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.74223754 |
| 33 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.72659326 |
| 34 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.70088439 |
| 35 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.62965682 |
| 36 | GATA1_22025678_ChIP-Seq_K562_Human | 1.61055255 |
| 37 | UTX_26944678_Chip-Seq_JUKART_Human | 1.56320033 |
| 38 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.56189582 |
| 39 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.55423675 |
| 40 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.55421207 |
| 41 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.53442606 |
| 42 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.51487914 |
| 43 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.50899095 |
| 44 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.50204393 |
| 45 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.50139027 |
| 46 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.45496057 |
| 47 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.43138452 |
| 48 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.40124738 |
| 49 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.35521382 |
| 50 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.28247053 |
| 51 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.19451942 |
| 52 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.16348398 |
| 53 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15648969 |
| 54 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.14331873 |
| 55 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.14182578 |
| 56 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.12549232 |
| 57 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.11729390 |
| 58 | MYC_22102868_ChIP-Seq_BL_Human | 1.09708587 |
| 59 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09183925 |
| 60 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.07472668 |
| 61 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.05879406 |
| 62 | MAF_26560356_Chip-Seq_TH2_Human | 1.03489230 |
| 63 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.01023772 |
| 64 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.00916564 |
| 65 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.98607934 |
| 66 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.98472218 |
| 67 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.97764397 |
| 68 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.97702921 |
| 69 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.95956333 |
| 70 | GATA2_19941826_ChIP-Seq_K562_Human | 0.93599497 |
| 71 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.91349668 |
| 72 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.89953373 |
| 73 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.89277123 |
| 74 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88712492 |
| 75 | GATA3_26560356_Chip-Seq_TH1_Human | 0.88203128 |
| 76 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.88182956 |
| 77 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.87694184 |
| 78 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.85841730 |
| 79 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.85797928 |
| 80 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.85007524 |
| 81 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84670896 |
| 82 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.84339149 |
| 83 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.83594570 |
| 84 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83059282 |
| 85 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.82765734 |
| 86 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.82543187 |
| 87 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.82044410 |
| 88 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.81819697 |
| 89 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.81052879 |
| 90 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.80998327 |
| 91 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.80464379 |
| 92 | GATA1_19941826_ChIP-Seq_K562_Human | 0.79876155 |
| 93 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.79084677 |
| 94 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.78727632 |
| 95 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.77727151 |
| 96 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.75053372 |
| 97 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.74636290 |
| 98 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.72111450 |
| 99 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.70883653 |
| 100 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.70810690 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 5.16942215 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.70835135 |
| 3 | MP0003763_abnormal_thymus_physiology | 3.28727761 |
| 4 | MP0003436_decreased_susceptibility_to | 3.25084553 |
| 5 | MP0000569_abnormal_digit_pigmentation | 3.18293905 |
| 6 | MP0005671_abnormal_response_to | 3.16637458 |
| 7 | MP0001800_abnormal_humoral_immune | 3.06921259 |
| 8 | MP0008260_abnormal_autophagy | 2.79767414 |
| 9 | MP0003303_peritoneal_inflammation | 2.70861997 |
| 10 | MP0000685_abnormal_immune_system | 2.62396203 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.58666943 |
| 12 | MP0002419_abnormal_innate_immunity | 2.57433926 |
| 13 | MP0002723_abnormal_immune_serum | 2.52895023 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.47358205 |
| 15 | MP0009785_altered_susceptibility_to | 2.46619402 |
| 16 | MP0001819_abnormal_immune_cell | 2.44745380 |
| 17 | MP0005025_abnormal_response_to | 2.41411272 |
| 18 | MP0002452_abnormal_antigen_presenting | 2.41380336 |
| 19 | MP0004381_abnormal_hair_follicle | 2.30541710 |
| 20 | MP0005387_immune_system_phenotype | 2.24332590 |
| 21 | MP0001790_abnormal_immune_system | 2.24332590 |
| 22 | MP0008057_abnormal_DNA_replication | 2.20229872 |
| 23 | MP0002398_abnormal_bone_marrow | 2.17894298 |
| 24 | MP0002166_altered_tumor_susceptibility | 2.10712586 |
| 25 | MP0003787_abnormal_imprinting | 2.05157066 |
| 26 | MP0000716_abnormal_immune_system | 2.01461003 |
| 27 | MP0002396_abnormal_hematopoietic_system | 2.00837896 |
| 28 | MP0003300_gastrointestinal_ulcer | 1.98338668 |
| 29 | MP0002405_respiratory_system_inflammati | 1.94156693 |
| 30 | MP0000465_gastrointestinal_hemorrhage | 1.93160091 |
| 31 | MP0000703_abnormal_thymus_morphology | 1.91712019 |
| 32 | MP0003828_pulmonary_edema | 1.91551676 |
| 33 | MP0000689_abnormal_spleen_morphology | 1.85743721 |
| 34 | MP0002722_abnormal_immune_system | 1.81835017 |
| 35 | MP0002148_abnormal_hypersensitivity_rea | 1.78706965 |
| 36 | MP0005451_abnormal_body_composition | 1.75562527 |
| 37 | MP0008877_abnormal_DNA_methylation | 1.74731801 |
| 38 | MP0006082_CNS_inflammation | 1.72222223 |
| 39 | MP0004883_abnormal_blood_vessel | 1.70876535 |
| 40 | MP0005464_abnormal_platelet_physiology | 1.67705823 |
| 41 | MP0005075_abnormal_melanosome_morpholog | 1.61528451 |
| 42 | MP0003191_abnormal_cellular_cholesterol | 1.60280768 |
| 43 | MP0003866_abnormal_defecation | 1.59599291 |
| 44 | MP0002429_abnormal_blood_cell | 1.59031509 |
| 45 | MP0010155_abnormal_intestine_physiology | 1.56520705 |
| 46 | MP0003172_abnormal_lysosome_physiology | 1.56465619 |
| 47 | MP0002009_preneoplasia | 1.56116649 |
| 48 | MP0001845_abnormal_inflammatory_respons | 1.55480182 |
| 49 | MP0001533_abnormal_skeleton_physiology | 1.52834954 |
| 50 | MP0009333_abnormal_splenocyte_physiolog | 1.50219060 |
| 51 | MP0002277_abnormal_respiratory_mucosa | 1.49971438 |
| 52 | MP0004947_skin_inflammation | 1.45969624 |
| 53 | MP0002006_tumorigenesis | 1.44936527 |
| 54 | MP0003221_abnormal_cardiomyocyte_apopto | 1.41852808 |
| 55 | MP0002132_abnormal_respiratory_system | 1.41441133 |
| 56 | MP0003656_abnormal_erythrocyte_physiolo | 1.40293524 |
| 57 | MP0005310_abnormal_salivary_gland | 1.37575136 |
| 58 | MP0000015_abnormal_ear_pigmentation | 1.26904832 |
| 59 | MP0009764_decreased_sensitivity_to | 1.26167436 |
| 60 | MP0003183_abnormal_peptide_metabolism | 1.22375433 |
| 61 | MP0000858_altered_metastatic_potential | 1.20867101 |
| 62 | MP0001851_eye_inflammation | 1.20475960 |
| 63 | MP0005164_abnormal_response_to | 1.20073450 |
| 64 | MP0005397_hematopoietic_system_phenotyp | 1.13987807 |
| 65 | MP0001545_abnormal_hematopoietic_system | 1.13987807 |
| 66 | MP0009278_abnormal_bone_marrow | 1.10014949 |
| 67 | MP0006054_spinal_hemorrhage | 1.08511530 |
| 68 | MP0008469_abnormal_protein_level | 1.06293364 |
| 69 | MP0004808_abnormal_hematopoietic_stem | 0.98825997 |
| 70 | MP0005174_abnormal_tail_pigmentation | 0.98645335 |
| 71 | MP0002998_abnormal_bone_remodeling | 0.91596593 |
| 72 | MP0003690_abnormal_glial_cell | 0.91422085 |
| 73 | MP0004484_altered_response_of | 0.91054720 |
| 74 | MP0003448_altered_tumor_morphology | 0.88285564 |
| 75 | MP0001853_heart_inflammation | 0.80977730 |
| 76 | MP0002138_abnormal_hepatobiliary_system | 0.78408525 |
| 77 | MP0004130_abnormal_muscle_cell | 0.78113557 |
| 78 | MP0004264_abnormal_extraembryonic_tissu | 0.77306680 |
| 79 | MP0002019_abnormal_tumor_incidence | 0.75893548 |
| 80 | MP0009763_increased_sensitivity_to | 0.70653802 |
| 81 | MP0000604_amyloidosis | 0.67382384 |
| 82 | MP0000249_abnormal_blood_vessel | 0.64282899 |
| 83 | MP0002133_abnormal_respiratory_system | 0.64279674 |
| 84 | MP0005388_respiratory_system_phenotype | 0.64279674 |
| 85 | MP0002933_joint_inflammation | 0.61398652 |
| 86 | MP0000371_diluted_coat_color | 0.61154093 |
| 87 | MP0003252_abnormal_bile_duct | 0.59886639 |
| 88 | MP0009765_abnormal_xenobiotic_induced | 0.59224978 |
| 89 | MP0005376_homeostasis/metabolism_phenot | 0.58417330 |
| 90 | MP0008004_abnormal_stomach_pH | 0.55627235 |
| 91 | MP0001873_stomach_inflammation | 0.53745584 |
| 92 | MP0002332_abnormal_exercise_endurance | 0.53422270 |
| 93 | MP0003091_abnormal_cell_migration | 0.53355219 |
| 94 | MP0005166_decreased_susceptibility_to | 0.53337253 |
| 95 | MP0003121_genomic_imprinting | 0.53095552 |
| 96 | MP0003045_fibrosis | 0.53085919 |
| 97 | MP0002928_abnormal_bile_duct | 0.51520572 |
| 98 | MP0005076_abnormal_cell_differentiation | 0.50798779 |
| 99 | MP0005621_abnormal_cell_physiology | 0.49117396 |
| 100 | MP0001663_abnormal_digestive_system | 0.48627857 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 6.13926929 |
| 2 | Eczematoid dermatitis (HP:0000976) | 5.86711509 |
| 3 | Abnormality of T cell number (HP:0011839) | 5.70422213 |
| 4 | Recurrent bacterial skin infections (HP:0005406) | 5.56573027 |
| 5 | Recurrent abscess formation (HP:0002722) | 5.17839204 |
| 6 | Retrobulbar optic neuritis (HP:0100654) | 5.16618560 |
| 7 | Optic neuritis (HP:0100653) | 5.16618560 |
| 8 | Myositis (HP:0100614) | 5.02273787 |
| 9 | Orchitis (HP:0100796) | 5.01636843 |
| 10 | Stomatitis (HP:0010280) | 4.58377156 |
| 11 | Recurrent fungal infections (HP:0002841) | 4.50254359 |
| 12 | Gastrointestinal infarctions (HP:0005244) | 4.39775742 |
| 13 | Abnormality of T cells (HP:0002843) | 3.95490861 |
| 14 | Keratoconjunctivitis sicca (HP:0001097) | 3.94458474 |
| 15 | Spontaneous hematomas (HP:0007420) | 3.93586414 |
| 16 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.90460394 |
| 17 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 3.88583255 |
| 18 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.87331604 |
| 19 | Recurrent cutaneous fungal infections (HP:0011370) | 3.87331604 |
| 20 | Recurrent skin infections (HP:0001581) | 3.83054346 |
| 21 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.82456582 |
| 22 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.74321204 |
| 23 | Keratoconjunctivitis (HP:0001096) | 3.67625869 |
| 24 | Encephalitis (HP:0002383) | 3.66381436 |
| 25 | Mediastinal lymphadenopathy (HP:0100721) | 3.56158850 |
| 26 | Abnormality of macrophages (HP:0004311) | 3.52574614 |
| 27 | Meningitis (HP:0001287) | 3.49797655 |
| 28 | Gingivitis (HP:0000230) | 3.49073088 |
| 29 | Leukocytosis (HP:0001974) | 3.39143993 |
| 30 | Vasculitis (HP:0002633) | 3.32105707 |
| 31 | Recurrent viral infections (HP:0004429) | 3.26926578 |
| 32 | Chest pain (HP:0100749) | 3.16604700 |
| 33 | Arterial thrombosis (HP:0004420) | 3.16263397 |
| 34 | Subacute progressive viral hepatitis (HP:0006572) | 3.09216978 |
| 35 | Hemoptysis (HP:0002105) | 3.07978993 |
| 36 | Gingival bleeding (HP:0000225) | 3.07152948 |
| 37 | Eosinophilia (HP:0001880) | 2.92730945 |
| 38 | Pulmonary infiltrates (HP:0002113) | 2.91221556 |
| 39 | Abnormality of eosinophils (HP:0001879) | 2.89932666 |
| 40 | Obstructive lung disease (HP:0006536) | 2.88408916 |
| 41 | Chronic obstructive pulmonary disease (HP:0006510) | 2.88408916 |
| 42 | Recurrent bronchitis (HP:0002837) | 2.85315698 |
| 43 | Peritonitis (HP:0002586) | 2.84372181 |
| 44 | Urticaria (HP:0001025) | 2.83959939 |
| 45 | Autoimmune hemolytic anemia (HP:0001890) | 2.82758552 |
| 46 | Hypochromic microcytic anemia (HP:0004840) | 2.81885914 |
| 47 | Granulocytopenia (HP:0001913) | 2.76711122 |
| 48 | IgG deficiency (HP:0004315) | 2.70037085 |
| 49 | IgM deficiency (HP:0002850) | 2.65533542 |
| 50 | Panhypogammaglobulinemia (HP:0003139) | 2.65440476 |
| 51 | Pulmonary embolism (HP:0002204) | 2.62453417 |
| 52 | Severe combined immunodeficiency (HP:0004430) | 2.61547212 |
| 53 | Anorexia (HP:0002039) | 2.59687727 |
| 54 | Lymphopenia (HP:0001888) | 2.58932345 |
| 55 | Stomach cancer (HP:0012126) | 2.57890035 |
| 56 | Viral hepatitis (HP:0006562) | 2.57260905 |
| 57 | Pustule (HP:0200039) | 2.54910134 |
| 58 | Thyroiditis (HP:0100646) | 2.53482049 |
| 59 | Inflammation of the large intestine (HP:0002037) | 2.52892978 |
| 60 | Abnormality of T cell physiology (HP:0011840) | 2.52209085 |
| 61 | Cellulitis (HP:0100658) | 2.49291129 |
| 62 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.45583747 |
| 63 | Epistaxis (HP:0000421) | 2.39874556 |
| 64 | Osteomyelitis (HP:0002754) | 2.39329300 |
| 65 | Gangrene (HP:0100758) | 2.37104750 |
| 66 | Chronic diarrhea (HP:0002028) | 2.36793891 |
| 67 | Gastrointestinal inflammation (HP:0004386) | 2.35032737 |
| 68 | Prolonged bleeding time (HP:0003010) | 2.32921519 |
| 69 | Hypochromic anemia (HP:0001931) | 2.31188230 |
| 70 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.26391099 |
| 71 | Increased IgM level (HP:0003496) | 2.24829670 |
| 72 | Slow saccadic eye movements (HP:0000514) | 2.24687405 |
| 73 | Increased IgE level (HP:0003212) | 2.22190262 |
| 74 | Microcytic anemia (HP:0001935) | 2.22013954 |
| 75 | Sepsis (HP:0100806) | 2.15993860 |
| 76 | Acute hepatic failure (HP:0006554) | 2.15087871 |
| 77 | Papillary thyroid carcinoma (HP:0002895) | 2.14542892 |
| 78 | Colitis (HP:0002583) | 2.13399850 |
| 79 | Keratitis (HP:0000491) | 2.13064608 |
| 80 | Abnormality of the peritoneum (HP:0002585) | 2.11567373 |
| 81 | Combined immunodeficiency (HP:0005387) | 2.11083841 |
| 82 | Episodic fever (HP:0001954) | 2.10953785 |
| 83 | Hypoplasia of the thymus (HP:0000778) | 2.08345266 |
| 84 | Abnormality of the endocardium (HP:0004306) | 2.04517373 |
| 85 | Abnormality of the pleura (HP:0002103) | 2.02081223 |
| 86 | Periodontitis (HP:0000704) | 2.01946027 |
| 87 | Abnormality of the fingertips (HP:0001211) | 2.01202817 |
| 88 | Papilloma (HP:0012740) | 2.00918494 |
| 89 | Verrucae (HP:0200043) | 2.00918494 |
| 90 | Hematochezia (HP:0002573) | 1.97663097 |
| 91 | IgA deficiency (HP:0002720) | 1.94857566 |
| 92 | Agammaglobulinemia (HP:0004432) | 1.94704938 |
| 93 | Amaurosis fugax (HP:0100576) | 1.94692590 |
| 94 | Abnormality of B cell number (HP:0010975) | 1.93283917 |
| 95 | Alveolar cell carcinoma (HP:0006519) | 1.93091267 |
| 96 | Thrombophlebitis (HP:0004418) | 1.91904149 |
| 97 | Glomerulopathy (HP:0100820) | 1.84602662 |
| 98 | Lymphoma (HP:0002665) | 1.83044180 |
| 99 | Autoimmune thrombocytopenia (HP:0001973) | 1.82315271 |
| 100 | Cheilitis (HP:0100825) | 1.79543665 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 3.96615203 |
| 2 | MAP4K1 | 3.18342889 |
| 3 | TXK | 2.96952539 |
| 4 | BLK | 2.96564616 |
| 5 | IRAK4 | 2.81620608 |
| 6 | CSK | 2.70651348 |
| 7 | TAOK3 | 2.56158787 |
| 8 | TYK2 | 2.52427197 |
| 9 | GRK6 | 2.46986495 |
| 10 | FES | 2.44232717 |
| 11 | MAP3K14 | 2.15363164 |
| 12 | IKBKE | 2.04975765 |
| 13 | MAP2K3 | 2.00910499 |
| 14 | JAK3 | 1.98117456 |
| 15 | BTK | 1.94261960 |
| 16 | JAK1 | 1.91471333 |
| 17 | FGR | 1.90283112 |
| 18 | ZAP70 | 1.85148155 |
| 19 | SYK | 1.73692081 |
| 20 | NLK | 1.71947924 |
| 21 | TEC | 1.70769566 |
| 22 | YES1 | 1.64009862 |
| 23 | HCK | 1.61107215 |
| 24 | MAP3K2 | 1.60898430 |
| 25 | ITK | 1.54866654 |
| 26 | FGFR3 | 1.51661558 |
| 27 | IRAK1 | 1.45833270 |
| 28 | JAK2 | 1.42153516 |
| 29 | ACVR1B | 1.40536578 |
| 30 | EPHB1 | 1.40256897 |
| 31 | MAP3K13 | 1.37019831 |
| 32 | LYN | 1.36182333 |
| 33 | PIK3CG | 1.35808278 |
| 34 | BMPR2 | 1.31135175 |
| 35 | PRPF4B | 1.25988871 |
| 36 | LCK | 1.25084181 |
| 37 | FRK | 1.12352551 |
| 38 | STK10 | 1.09681027 |
| 39 | IRAK2 | 1.09410923 |
| 40 | MARK3 | 1.08277290 |
| 41 | CAMKK2 | 1.05737145 |
| 42 | SIK3 | 1.04511245 |
| 43 | MAP3K6 | 1.03804200 |
| 44 | MAP3K1 | 1.02616422 |
| 45 | MATK | 1.00814802 |
| 46 | TNK2 | 0.99358485 |
| 47 | WNK1 | 0.99005586 |
| 48 | KSR2 | 0.98628831 |
| 49 | PIM1 | 0.97620266 |
| 50 | SGK2 | 0.97450759 |
| 51 | MAP3K10 | 0.90361742 |
| 52 | FGFR4 | 0.88823088 |
| 53 | STK4 | 0.87586178 |
| 54 | LRRK2 | 0.87316572 |
| 55 | RAF1 | 0.82833786 |
| 56 | MARK2 | 0.82242475 |
| 57 | CSF1R | 0.79167327 |
| 58 | SGK3 | 0.78283039 |
| 59 | KSR1 | 0.78004128 |
| 60 | TGFBR2 | 0.77736421 |
| 61 | BRD4 | 0.77292966 |
| 62 | KIT | 0.74894800 |
| 63 | TBK1 | 0.72423764 |
| 64 | PRKCQ | 0.71780619 |
| 65 | CDK19 | 0.71756200 |
| 66 | PTK2B | 0.71650709 |
| 67 | IKBKB | 0.70465676 |
| 68 | MAP3K3 | 0.69101616 |
| 69 | EPHA3 | 0.68956486 |
| 70 | NUAK1 | 0.68696892 |
| 71 | MAP3K7 | 0.67210098 |
| 72 | MAP3K5 | 0.65027963 |
| 73 | PDK1 | 0.63434662 |
| 74 | ERN1 | 0.61033310 |
| 75 | DYRK3 | 0.59389420 |
| 76 | NEK6 | 0.58479790 |
| 77 | STK11 | 0.57527823 |
| 78 | EGFR | 0.55186936 |
| 79 | TAOK1 | 0.54788997 |
| 80 | MELK | 0.54371114 |
| 81 | CDK6 | 0.53743777 |
| 82 | MAP2K4 | 0.50532102 |
| 83 | FYN | 0.49536934 |
| 84 | DYRK1B | 0.48353767 |
| 85 | CAMK4 | 0.48010736 |
| 86 | ERBB2 | 0.46582956 |
| 87 | CLK1 | 0.46024201 |
| 88 | RET | 0.45579168 |
| 89 | DYRK1A | 0.44294973 |
| 90 | STK38 | 0.44024980 |
| 91 | CDK4 | 0.43966639 |
| 92 | GRK5 | 0.43242451 |
| 93 | MST4 | 0.42089497 |
| 94 | CDK12 | 0.40497981 |
| 95 | CAMKK1 | 0.38114497 |
| 96 | MAPK7 | 0.37461972 |
| 97 | SGK223 | 0.37286978 |
| 98 | SGK494 | 0.37286978 |
| 99 | PTK6 | 0.37097492 |
| 100 | SGK1 | 0.37001857 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.79031976 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.67757783 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.58047584 |
| 4 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.56048377 |
| 5 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.45827983 |
| 6 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.34855876 |
| 7 | Measles_Homo sapiens_hsa05162 | 2.21265567 |
| 8 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.13332483 |
| 9 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.07441989 |
| 10 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.04600083 |
| 11 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.01591584 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.00127004 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.96205193 |
| 14 | Tuberculosis_Homo sapiens_hsa05152 | 1.90188964 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.88557172 |
| 16 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.87709162 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.85394417 |
| 18 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.79915278 |
| 19 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.76969784 |
| 20 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.68537890 |
| 21 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.67675205 |
| 22 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.66637589 |
| 23 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.65510247 |
| 24 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.59487150 |
| 25 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.58558038 |
| 26 | Legionellosis_Homo sapiens_hsa05134 | 1.51583284 |
| 27 | Influenza A_Homo sapiens_hsa05164 | 1.50327530 |
| 28 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.49550248 |
| 29 | Hepatitis B_Homo sapiens_hsa05161 | 1.45870964 |
| 30 | Malaria_Homo sapiens_hsa05144 | 1.45629049 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.44163469 |
| 32 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.35346936 |
| 33 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.34081408 |
| 34 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.34069457 |
| 35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.27405544 |
| 36 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.27286611 |
| 37 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.24639510 |
| 38 | Platelet activation_Homo sapiens_hsa04611 | 1.20612363 |
| 39 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.15461975 |
| 40 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.14839243 |
| 41 | Viral myocarditis_Homo sapiens_hsa05416 | 1.14288374 |
| 42 | Hepatitis C_Homo sapiens_hsa05160 | 1.13231695 |
| 43 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.12994505 |
| 44 | FoxO signaling pathway_Homo sapiens_hsa04068 | 1.11106331 |
| 45 | Apoptosis_Homo sapiens_hsa04210 | 1.10114115 |
| 46 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.08438171 |
| 47 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.04097054 |
| 48 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.95756846 |
| 49 | Endometrial cancer_Homo sapiens_hsa05213 | 0.95309977 |
| 50 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.94732736 |
| 51 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.91765372 |
| 52 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.89291912 |
| 53 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.85997671 |
| 54 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.85232127 |
| 55 | Colorectal cancer_Homo sapiens_hsa05210 | 0.84744685 |
| 56 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.83274522 |
| 57 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.83014297 |
| 58 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.81541434 |
| 59 | Shigellosis_Homo sapiens_hsa05131 | 0.80183894 |
| 60 | Asthma_Homo sapiens_hsa05310 | 0.80179351 |
| 61 | Phagosome_Homo sapiens_hsa04145 | 0.80167771 |
| 62 | Prostate cancer_Homo sapiens_hsa05215 | 0.76694188 |
| 63 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.76124124 |
| 64 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.74620761 |
| 65 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.72133080 |
| 66 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.71606331 |
| 67 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.70063009 |
| 68 | Thyroid cancer_Homo sapiens_hsa05216 | 0.69267330 |
| 69 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67546289 |
| 70 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.65552545 |
| 71 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.65016802 |
| 72 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.64424936 |
| 73 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64046355 |
| 74 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.62733852 |
| 75 | Pertussis_Homo sapiens_hsa05133 | 0.61942504 |
| 76 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.59436213 |
| 77 | HTLV-I infection_Homo sapiens_hsa05166 | 0.57739978 |
| 78 | Endocytosis_Homo sapiens_hsa04144 | 0.56938499 |
| 79 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.55191676 |
| 80 | Salmonella infection_Homo sapiens_hsa05132 | 0.53788410 |
| 81 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.53593363 |
| 82 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.52976826 |
| 83 | Insulin resistance_Homo sapiens_hsa04931 | 0.52212154 |
| 84 | Glioma_Homo sapiens_hsa05214 | 0.51281975 |
| 85 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.50340283 |
| 86 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.50053402 |
| 87 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.48689931 |
| 88 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.45667696 |
| 89 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.45538776 |
| 90 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.43226312 |
| 91 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42571142 |
| 92 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.42327471 |
| 93 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.41169560 |
| 94 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.40609334 |
| 95 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.39660592 |
| 96 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.39643706 |
| 97 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.39281573 |
| 98 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.39235464 |
| 99 | Long-term potentiation_Homo sapiens_hsa04720 | 0.38787574 |
| 100 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.38469697 |

