KIDINS220

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane assembly (GO:0097105)5.32009280
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.28727862
3nucleobase catabolic process (GO:0046113)5.22715525
4locomotory exploration behavior (GO:0035641)5.21500523
5synaptic vesicle maturation (GO:0016188)5.11499917
6presynaptic membrane organization (GO:0097090)4.95754571
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.78535375
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.59833793
9layer formation in cerebral cortex (GO:0021819)4.55512142
10vocalization behavior (GO:0071625)4.45696926
11regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.39215498
12synaptic vesicle exocytosis (GO:0016079)4.26457173
13regulation of glutamate receptor signaling pathway (GO:1900449)4.18829549
14regulation of synaptic vesicle exocytosis (GO:2000300)4.10794586
15exploration behavior (GO:0035640)4.01905545
16glutamate secretion (GO:0014047)4.00406054
17ionotropic glutamate receptor signaling pathway (GO:0035235)3.98361307
18neuron cell-cell adhesion (GO:0007158)3.94909007
19protein localization to synapse (GO:0035418)3.94798335
20regulation of synapse structural plasticity (GO:0051823)3.91116684
21synaptic vesicle docking involved in exocytosis (GO:0016081)3.88320892
22dendritic spine morphogenesis (GO:0060997)3.85825941
23proline transport (GO:0015824)3.79830054
24* dendrite morphogenesis (GO:0048813)3.76273197
25cellular potassium ion homeostasis (GO:0030007)3.74030841
26sodium ion export (GO:0071436)3.73729881
27central nervous system neuron axonogenesis (GO:0021955)3.72429009
28neurotransmitter secretion (GO:0007269)3.71803436
29establishment of mitochondrion localization (GO:0051654)3.67375771
30gamma-aminobutyric acid transport (GO:0015812)3.64670694
31axonal fasciculation (GO:0007413)3.58972691
32neurotransmitter-gated ion channel clustering (GO:0072578)3.58833647
33regulation of synaptic vesicle transport (GO:1902803)3.58685732
34neuron recognition (GO:0008038)3.57019816
35regulation of neuronal synaptic plasticity (GO:0048168)3.55936993
36positive regulation of synapse assembly (GO:0051965)3.53690793
37regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.53390650
38glutamate receptor signaling pathway (GO:0007215)3.52958836
39membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.52499510
40regulation of long-term neuronal synaptic plasticity (GO:0048169)3.47259448
41synaptic transmission, glutamatergic (GO:0035249)3.45796314
42activation of protein kinase A activity (GO:0034199)3.42483651
43cerebral cortex radially oriented cell migration (GO:0021799)3.32740712
44cell communication by electrical coupling (GO:0010644)3.30807611
45cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.26875679
46negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.26485978
47calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.25307235
48long-term memory (GO:0007616)3.25260752
49regulation of synapse assembly (GO:0051963)3.23995052
50cerebellar Purkinje cell differentiation (GO:0021702)3.22366800
51positive regulation of synapse maturation (GO:0090129)3.22127558
52cell migration in hindbrain (GO:0021535)3.21420469
53regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.19551662
54neuromuscular process controlling balance (GO:0050885)3.17631842
55neuron-neuron synaptic transmission (GO:0007270)3.16939853
56regulation of dendritic spine morphogenesis (GO:0061001)3.12862418
57regulation of ARF protein signal transduction (GO:0032012)3.10890846
58axon extension (GO:0048675)3.09237940
59prepulse inhibition (GO:0060134)3.08289741
60positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.08071622
61vesicle transport along microtubule (GO:0047496)3.06472135
62central nervous system projection neuron axonogenesis (GO:0021952)3.05653101
63mechanosensory behavior (GO:0007638)3.05566578
64regulation of excitatory postsynaptic membrane potential (GO:0060079)3.04968362
65membrane assembly (GO:0071709)3.03675685
66limb bud formation (GO:0060174)3.02730556
67establishment of nucleus localization (GO:0040023)3.00434486
68positive regulation of membrane potential (GO:0045838)2.99980834
69establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.98921078
70mitochondrion transport along microtubule (GO:0047497)2.98921078
71neuronal action potential propagation (GO:0019227)2.98103071
72transmission of nerve impulse (GO:0019226)2.96288302
73response to auditory stimulus (GO:0010996)2.96068388
74positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.95988092
75regulation of axon guidance (GO:1902667)2.95350550
76pyrimidine nucleobase catabolic process (GO:0006208)2.95266794
77neurotransmitter transport (GO:0006836)2.95014188
78negative regulation of dendrite development (GO:2000171)2.94761520
79regulation of postsynaptic membrane potential (GO:0060078)2.93684159
80clathrin coat assembly (GO:0048268)2.92343553
81auditory behavior (GO:0031223)2.92258583
82heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.90012721
83startle response (GO:0001964)2.89668920
84organelle transport along microtubule (GO:0072384)2.89648116
85innervation (GO:0060384)2.88982370
86alanine transport (GO:0032328)2.87273516
87synaptic vesicle endocytosis (GO:0048488)2.87120426
88axonogenesis (GO:0007409)2.86089085
89regulation of synaptic transmission, glutamatergic (GO:0051966)2.84070434
90membrane depolarization during action potential (GO:0086010)2.83251002
91glycosphingolipid biosynthetic process (GO:0006688)2.82781711
92positive regulation of synaptic transmission, GABAergic (GO:0032230)2.82686529
93postsynaptic membrane organization (GO:0001941)2.82641142
94neuronal ion channel clustering (GO:0045161)2.82476556
95neural tube formation (GO:0001841)2.82318979
96retinal ganglion cell axon guidance (GO:0031290)2.82175528
97dendrite development (GO:0016358)2.81575031
98cerebellar granule cell differentiation (GO:0021707)2.80540029
99regulation of synaptic plasticity (GO:0048167)2.78671503
100cerebellar Purkinje cell layer development (GO:0021680)2.78477552
101regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.78409005
102potassium ion import (GO:0010107)2.77317391
103synapse assembly (GO:0007416)2.76709474
104regulation of synapse organization (GO:0050807)2.75579298
105cellular sodium ion homeostasis (GO:0006883)2.74958884
106glycine transport (GO:0015816)2.74653760
107regulation of neurotransmitter secretion (GO:0046928)2.73349208
108negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.72396478
109negative regulation of translation, ncRNA-mediated (GO:0040033)2.72396478
110regulation of translation, ncRNA-mediated (GO:0045974)2.72396478
111regulation of neurotransmitter levels (GO:0001505)2.72355722
112cardiac ventricle formation (GO:0003211)2.72209805
113G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.71227333
114neurofilament cytoskeleton organization (GO:0060052)2.71211760
115regulation of axon extension involved in axon guidance (GO:0048841)2.69700793
116epithelial cell differentiation involved in kidney development (GO:0035850)2.69567331
117regulation of vesicle fusion (GO:0031338)2.67912880
118synapse organization (GO:0050808)2.67509535
119positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.67213716
120negative regulation of cytosolic calcium ion concentration (GO:0051481)2.67011393
121neuronal action potential (GO:0019228)2.66146339
122hippocampus development (GO:0021766)2.65831414
123regulation of dendritic spine development (GO:0060998)2.65643903
124positive regulation of potassium ion transmembrane transport (GO:1901381)2.64616209
125mating behavior (GO:0007617)2.64571806
126positive regulation of dendritic spine development (GO:0060999)2.64177113
127neuron projection extension (GO:1990138)2.64115896
128membrane hyperpolarization (GO:0060081)2.63128233
129potassium ion homeostasis (GO:0055075)2.62633046
130negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.62435578
131long-term synaptic potentiation (GO:0060291)2.61983371
132dopamine receptor signaling pathway (GO:0007212)2.61158253
133membrane depolarization (GO:0051899)2.61068288
134positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.60921852
135cell communication involved in cardiac conduction (GO:0086065)2.60185937
136cardiac chamber formation (GO:0003207)2.59687548
137axon cargo transport (GO:0008088)2.59614280
138cerebral cortex cell migration (GO:0021795)2.59301977
139dendritic spine organization (GO:0097061)2.58861188
140G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.58822333
141positive regulation of dendritic spine morphogenesis (GO:0061003)2.56819580
142neuron migration (GO:0001764)2.56799455
143adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.55432482
144adult walking behavior (GO:0007628)2.55336251

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.94638774
2GBX2_23144817_ChIP-Seq_PC3_Human3.06468779
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.70810787
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.67891729
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.56155703
6DROSHA_22980978_ChIP-Seq_HELA_Human2.54839341
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.40261508
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.40261508
9MTF2_20144788_ChIP-Seq_MESCs_Mouse2.29305013
10REST_21632747_ChIP-Seq_MESCs_Mouse2.29024271
11SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.26705810
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.25198241
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.25003281
14RARB_27405468_Chip-Seq_BRAIN_Mouse2.24263321
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.22058884
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.20017467
17SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.19291778
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.14610422
19ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.07320182
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.01955551
21SUZ12_27294783_Chip-Seq_ESCs_Mouse1.98489851
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.97394217
23AR_21572438_ChIP-Seq_LNCaP_Human1.95394345
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.95089005
25EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.93202909
26EED_16625203_ChIP-ChIP_MESCs_Mouse1.91027297
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.82524706
28REST_18959480_ChIP-ChIP_MESCs_Mouse1.81752055
29TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.75152437
30SALL1_21062744_ChIP-ChIP_HESCs_Human1.73259392
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.69579798
32FUS_26573619_Chip-Seq_HEK293_Human1.69320084
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.64674338
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.62675065
35MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.60911047
36RNF2_27304074_Chip-Seq_NSC_Mouse1.60283709
37* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56441843
38IKZF1_21737484_ChIP-ChIP_HCT116_Human1.55990783
39CTBP2_25329375_ChIP-Seq_LNCAP_Human1.55412972
40PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.52180771
41TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.50865883
42POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.50865883
43* SMAD4_21799915_ChIP-Seq_A2780_Human1.49946600
44ZNF274_21170338_ChIP-Seq_K562_Hela1.44892510
45ZNF217_24962896_ChIP-Seq_MCF-7_Human1.43359090
46CDX2_19796622_ChIP-Seq_MESCs_Mouse1.43025916
47BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39942280
48SOX2_21211035_ChIP-Seq_LN229_Gbm1.38273250
49GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36886257
50TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.36018607
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.34521745
52WT1_25993318_ChIP-Seq_PODOCYTE_Human1.33375175
53NR3C1_23031785_ChIP-Seq_PC12_Mouse1.32367339
54AHR_22903824_ChIP-Seq_MCF-7_Human1.31240160
55SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.29907030
56ARNT_22903824_ChIP-Seq_MCF-7_Human1.29821386
57TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.28750978
58WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.28243850
59NANOG_18555785_Chip-Seq_ESCs_Mouse1.28181895
60* AR_19668381_ChIP-Seq_PC3_Human1.27583825
61ERG_21242973_ChIP-ChIP_JURKAT_Human1.27429929
62KDM2B_26808549_Chip-Seq_K562_Human1.26185089
63EWS_26573619_Chip-Seq_HEK293_Human1.25174569
64* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.25087876
65TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.24901693
66RING1B_27294783_Chip-Seq_ESCs_Mouse1.24884645
67STAT3_23295773_ChIP-Seq_U87_Human1.24251739
68VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.24176900
69PIAS1_25552417_ChIP-Seq_VCAP_Human1.23979182
70SMAD_19615063_ChIP-ChIP_OVARY_Human1.22690070
71LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21490018
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.19928399
73AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.19374579
74STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.19345443
75RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.17923356
76* AR_25329375_ChIP-Seq_VCAP_Human1.17124401
77ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.16844073
78IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.16454225
79CBP_20019798_ChIP-Seq_JUKART_Human1.16454225
80KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.16161467
81TCF4_18268006_ChIP-ChIP_LS174T_Human1.15800395
82TP53_16413492_ChIP-PET_HCT116_Human1.15604844
83CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.14688288
84P300_19829295_ChIP-Seq_ESCs_Human1.14482327
85YAP1_20516196_ChIP-Seq_MESCs_Mouse1.14472456
86* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14100625
87TAF15_26573619_Chip-Seq_HEK293_Human1.14043743
88WT1_19549856_ChIP-ChIP_CCG9911_Human1.13849664
89NRF2_20460467_ChIP-Seq_MEFs_Mouse1.13403257
90NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.13403257
91* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12618627
92ER_23166858_ChIP-Seq_MCF-7_Human1.12315123
93DNAJC2_21179169_ChIP-ChIP_NT2_Human1.12056400
94RING1B_27294783_Chip-Seq_NPCs_Mouse1.11964069
95VDR_22108803_ChIP-Seq_LS180_Human1.11957879
96KDM2B_26808549_Chip-Seq_REH_Human1.11579956
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10580301
98PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.09527834
99TOP2B_26459242_ChIP-Seq_MCF-7_Human1.08484007
100P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08298913
101EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.06691865
102SMAD4_21741376_ChIP-Seq_HESCs_Human1.06289500
103TCF4_23295773_ChIP-Seq_U87_Human1.06271397
104ZFP57_27257070_Chip-Seq_ESCs_Mouse1.03581069
105ZFP281_18757296_ChIP-ChIP_E14_Mouse1.02447417
106NR3C1_21868756_ChIP-Seq_MCF10A_Human1.00719241
107RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.99116845
108SMAD3_21741376_ChIP-Seq_ESCs_Human0.98847783
109DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.98401747
110* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96579490
111BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.95689188
112SMAD3_21741376_ChIP-Seq_HESCs_Human0.95568115
113CTNNB1_20460455_ChIP-Seq_HCT116_Human0.95425979
114RXR_22108803_ChIP-Seq_LS180_Human0.94715424
115GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94674895
116CBX2_27304074_Chip-Seq_ESCs_Mouse0.94320397
117MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93649076
118IGF1R_20145208_ChIP-Seq_DFB_Human0.93607192
119BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.93204714
120EP300_21415370_ChIP-Seq_HL-1_Mouse0.92690144
121RUNX2_22187159_ChIP-Seq_PCA_Human0.92610806
122EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.92372902
123POU3F2_20337985_ChIP-ChIP_501MEL_Human0.89717778
124TP53_18474530_ChIP-ChIP_U2OS_Human0.89049738
125ZFP281_27345836_Chip-Seq_ESCs_Mouse0.88338561
126BCAT_22108803_ChIP-Seq_LS180_Human0.88183014
127TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88086690

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.15871717
2MP0003635_abnormal_synaptic_transmissio3.86392498
3MP0004270_analgesia3.74352725
4MP0003880_abnormal_central_pattern3.62832468
5MP0002063_abnormal_learning/memory/cond3.10046144
6MP0005423_abnormal_somatic_nervous2.94674664
7MP0009745_abnormal_behavioral_response2.91963508
8MP0009780_abnormal_chondrocyte_physiolo2.82746800
9MP0009046_muscle_twitch2.77689395
10MP0002064_seizures2.75332021
11MP0000569_abnormal_digit_pigmentation2.60103973
12MP0002734_abnormal_mechanical_nocicepti2.54022195
13MP0002572_abnormal_emotion/affect_behav2.46380438
14MP0001968_abnormal_touch/_nociception2.44790389
15MP0001486_abnormal_startle_reflex2.31301490
16MP0002909_abnormal_adrenal_gland2.30218289
17MP0000778_abnormal_nervous_system2.20447416
18MP0004858_abnormal_nervous_system2.14633560
19MP0002822_catalepsy2.13442189
20MP0002272_abnormal_nervous_system2.09084924
21MP0003329_amyloid_beta_deposits2.00676706
22MP0002733_abnormal_thermal_nociception1.96042886
23MP0002735_abnormal_chemical_nociception1.94967346
24MP0001440_abnormal_grooming_behavior1.91902975
25MP0004885_abnormal_endolymph1.89986724
26MP0008569_lethality_at_weaning1.88577910
27MP0002184_abnormal_innervation1.88194315
28MP0004811_abnormal_neuron_physiology1.83736264
29MP0002067_abnormal_sensory_capabilities1.80700339
30MP0001970_abnormal_pain_threshold1.74773975
31MP0001501_abnormal_sleep_pattern1.74645101
32MP0005386_behavior/neurological_phenoty1.70563087
33MP0004924_abnormal_behavior1.70563087
34MP0002736_abnormal_nociception_after1.69056276
35MP0000955_abnormal_spinal_cord1.68979825
36MP0002557_abnormal_social/conspecific_i1.68977359
37MP0003121_genomic_imprinting1.67061231
38MP0003787_abnormal_imprinting1.66605652
39MP0005646_abnormal_pituitary_gland1.54521202
40MP0001188_hyperpigmentation1.49227151
41MP0001984_abnormal_olfaction1.46763604
42* MP0002882_abnormal_neuron_morphology1.46019724
43MP0002102_abnormal_ear_morphology1.45667259
44MP0003633_abnormal_nervous_system1.37965215
45MP0002638_abnormal_pupillary_reflex1.34862126
46MP0002066_abnormal_motor_capabilities/c1.34083125
47MP0005645_abnormal_hypothalamus_physiol1.33662366
48MP0003283_abnormal_digestive_organ1.32878158
49MP0002751_abnormal_autonomic_nervous1.32339116
50MP0006276_abnormal_autonomic_nervous1.29448657
51MP0008961_abnormal_basal_metabolism1.28466269
52MP0001502_abnormal_circadian_rhythm1.25423461
53MP0001299_abnormal_eye_distance/1.25208803
54MP0003690_abnormal_glial_cell1.23718250
55MP0002152_abnormal_brain_morphology1.19209424
56MP0003879_abnormal_hair_cell1.18737192
57MP0003634_abnormal_glial_cell1.16213943
58MP0003631_nervous_system_phenotype1.16005429
59MP0000751_myopathy1.15322060
60MP0003890_abnormal_embryonic-extraembry1.08364951
61MP0005248_abnormal_Harderian_gland1.07539438
62MP0003122_maternal_imprinting1.05400980
63MP0003172_abnormal_lysosome_physiology1.05149253
64MP0000604_amyloidosis1.04146465
65MP0002229_neurodegeneration1.02642021
66MP0005187_abnormal_penis_morphology1.02488910
67MP0005253_abnormal_eye_physiology1.01716099
68MP0008789_abnormal_olfactory_epithelium1.01447695
69MP0005551_abnormal_eye_electrophysiolog0.99071176
70MP0001177_atelectasis0.98986988
71MP0000013_abnormal_adipose_tissue0.98145089
72MP0003632_abnormal_nervous_system0.96960053
73MP0002090_abnormal_vision0.95356556
74MP0004130_abnormal_muscle_cell0.95348637
75MP0004133_heterotaxia0.95210435
76MP0002069_abnormal_eating/drinking_beha0.94130284
77MP0004233_abnormal_muscle_weight0.92514244
78MP0005409_darkened_coat_color0.92150218
79MP0003385_abnormal_body_wall0.91007464
80MP0004085_abnormal_heartbeat0.89459550
81MP0000920_abnormal_myelination0.87723500
82MP0004043_abnormal_pH_regulation0.87368635
83MP0010386_abnormal_urinary_bladder0.86879753
84MP0000631_abnormal_neuroendocrine_gland0.86473632
85MP0004742_abnormal_vestibular_system0.84367511
86MP0002081_perinatal_lethality0.83586697
87MP0003119_abnormal_digestive_system0.83581723
88MP0010234_abnormal_vibrissa_follicle0.81563187
89MP0002233_abnormal_nose_morphology0.81477472
90MP0001905_abnormal_dopamine_level0.79962190
91MP0004145_abnormal_muscle_electrophysio0.79066931
92MP0005535_abnormal_body_temperature0.77978086
93MP0004142_abnormal_muscle_tone0.77022042
94MP0003045_fibrosis0.75457119
95MP0003137_abnormal_impulse_conducting0.74858098
96MP0003075_altered_response_to0.72068310
97MP0000049_abnormal_middle_ear0.71898489
98MP0002752_abnormal_somatic_nervous0.71107266
99MP0003183_abnormal_peptide_metabolism0.70613417
100MP0003221_abnormal_cardiomyocyte_apopto0.70547839
101MP0010768_mortality/aging0.70393716
102MP0003938_abnormal_ear_development0.70164300
103MP0003935_abnormal_craniofacial_develop0.69812880
104MP0000462_abnormal_digestive_system0.69806250
105MP0004215_abnormal_myocardial_fiber0.68866491
106MP0003937_abnormal_limbs/digits/tail_de0.67722478
107MP0005195_abnormal_posterior_eye0.67132640
108MP0000026_abnormal_inner_ear0.66724939
109MP0003861_abnormal_nervous_system0.65747457
110MP0008874_decreased_physiological_sensi0.65290739
111MP0008877_abnormal_DNA_methylation0.65240215
112MP0002089_abnormal_postnatal_growth/wei0.63683863
113MP0006072_abnormal_retinal_apoptosis0.63326211
114MP0005623_abnormal_meninges_morphology0.62744959
115MP0002837_dystrophic_cardiac_calcinosis0.61327069
116MP0001963_abnormal_hearing_physiology0.60069729
117MP0002234_abnormal_pharynx_morphology0.59712016
118MP0001943_abnormal_respiration0.58054531
119MP0005394_taste/olfaction_phenotype0.58017237
120MP0005499_abnormal_olfactory_system0.58017237
121MP0010769_abnormal_survival0.57339489
122MP0000534_abnormal_ureter_morphology0.56486346
123MP0010770_preweaning_lethality0.55773525
124MP0002082_postnatal_lethality0.55773525
125MP0001529_abnormal_vocalization0.55117826
126MP0001348_abnormal_lacrimal_gland0.54453710

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.01561147
2Myokymia (HP:0002411)4.98170955
3Focal seizures (HP:0007359)4.54928269
4Visual hallucinations (HP:0002367)4.04980633
5Supranuclear gaze palsy (HP:0000605)3.76910758
6Action tremor (HP:0002345)3.75335779
7Progressive cerebellar ataxia (HP:0002073)3.66576650
8Epileptic encephalopathy (HP:0200134)3.66356147
9Ankle clonus (HP:0011448)3.28722456
10Febrile seizures (HP:0002373)3.14508623
11Mutism (HP:0002300)3.10673491
12Absence seizures (HP:0002121)3.08558271
13Atonic seizures (HP:0010819)3.08403022
14Papilledema (HP:0001085)3.04980835
15Drooling (HP:0002307)2.99021665
16Excessive salivation (HP:0003781)2.99021665
17Genetic anticipation (HP:0003743)2.95677594
18Cortical dysplasia (HP:0002539)2.92801440
19Urinary bladder sphincter dysfunction (HP:0002839)2.91103461
20Protruding tongue (HP:0010808)2.90857219
21Generalized tonic-clonic seizures (HP:0002069)2.90611528
22Papillary thyroid carcinoma (HP:0002895)2.89032864
23Neurofibrillary tangles (HP:0002185)2.87253956
24Broad-based gait (HP:0002136)2.86107231
25Truncal ataxia (HP:0002078)2.83950397
26Depression (HP:0000716)2.81043411
27Megalencephaly (HP:0001355)2.80842324
28Impaired vibration sensation in the lower limbs (HP:0002166)2.80008219
29Poor eye contact (HP:0000817)2.78218207
30Impaired social interactions (HP:0000735)2.76072772
31Abnormal social behavior (HP:0012433)2.76072772
32Cerebral inclusion bodies (HP:0100314)2.75468988
33Dialeptic seizures (HP:0011146)2.73927602
34Macroorchidism (HP:0000053)2.68206939
35Urinary urgency (HP:0000012)2.67973498
36Hepatoblastoma (HP:0002884)2.66979000
37Insidious onset (HP:0003587)2.66669537
38Termporal pattern (HP:0011008)2.66669537
39Abnormality of the corticospinal tract (HP:0002492)2.66585681
40Dysdiadochokinesis (HP:0002075)2.61959515
41Abnormal eating behavior (HP:0100738)2.61883867
42Lissencephaly (HP:0001339)2.58188842
43Hemiparesis (HP:0001269)2.56937875
44Pachygyria (HP:0001302)2.56568605
45Postural instability (HP:0002172)2.54732925
46Progressive inability to walk (HP:0002505)2.51352387
47Spastic gait (HP:0002064)2.48737076
48Abnormality of the lower motor neuron (HP:0002366)2.48170913
49Agitation (HP:0000713)2.47317448
50Abnormality of binocular vision (HP:0011514)2.47053468
51Diplopia (HP:0000651)2.47053468
52Intention tremor (HP:0002080)2.44249225
53Dysmetria (HP:0001310)2.43926994
54Gaze-evoked nystagmus (HP:0000640)2.43905896
55Hypoplasia of the brainstem (HP:0002365)2.43599741
56Hemiplegia (HP:0002301)2.42723167
57Gait imbalance (HP:0002141)2.42540686
58Vitreoretinal degeneration (HP:0000655)2.36140145
59Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.34637999
60Degeneration of the lateral corticospinal tracts (HP:0002314)2.34637999
61Hyperventilation (HP:0002883)2.33557074
62Anxiety (HP:0000739)2.33242121
63EEG with generalized epileptiform discharges (HP:0011198)2.31394085
64Epileptiform EEG discharges (HP:0011182)2.30122102
65Torticollis (HP:0000473)2.27193334
66Inappropriate behavior (HP:0000719)2.26398256
67Hypsarrhythmia (HP:0002521)2.25162494
68Stereotypic behavior (HP:0000733)2.24998200
69Impaired smooth pursuit (HP:0007772)2.24827576
70Lower limb muscle weakness (HP:0007340)2.24503136
71Insomnia (HP:0100785)2.24025702
72Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.23194051
73Scanning speech (HP:0002168)2.22371164
74Amyotrophic lateral sclerosis (HP:0007354)2.16612684
75Hypoplasia of the corpus callosum (HP:0002079)2.13042382
76Polyphagia (HP:0002591)2.12799525
77Dysmetric saccades (HP:0000641)2.12656566
78Ulnar claw (HP:0001178)2.11163750
79Inability to walk (HP:0002540)2.10499865
80Spastic tetraplegia (HP:0002510)2.08956940
81Aqueductal stenosis (HP:0002410)2.08813334
82Pheochromocytoma (HP:0002666)2.07465118
83Neuronal loss in central nervous system (HP:0002529)2.07296051
84Blue irides (HP:0000635)2.07189848
85Amblyopia (HP:0000646)2.06577715
86Abnormality of ocular smooth pursuit (HP:0000617)2.05691094
87Failure to thrive in infancy (HP:0001531)2.03011266
88Intellectual disability, severe (HP:0010864)2.01038187
89Hip dysplasia (HP:0001385)1.99994948
90Limb dystonia (HP:0002451)1.98230411
91Pointed chin (HP:0000307)1.97835423
92Morphological abnormality of the pyramidal tract (HP:0002062)1.96655095
93Open mouth (HP:0000194)1.96248277
94Apathy (HP:0000741)1.93719030
95Thyroid carcinoma (HP:0002890)1.92921960
96Specific learning disability (HP:0001328)1.91276827
97Bradykinesia (HP:0002067)1.91245203
98Focal dystonia (HP:0004373)1.90932386
99Akinesia (HP:0002304)1.90708094
100Cutaneous finger syndactyly (HP:0010554)1.90470644
101Lower limb amyotrophy (HP:0007210)1.90038466
102Abnormality of the astrocytes (HP:0100707)1.89388563
103Astrocytoma (HP:0009592)1.89388563
104Abnormality of salivation (HP:0100755)1.89293937
105Lower limb asymmetry (HP:0100559)1.88600060
106Clonus (HP:0002169)1.87898427
107Hyperacusis (HP:0010780)1.84532236
108Sleep apnea (HP:0010535)1.84182586
109Genital tract atresia (HP:0001827)1.83105744
110Increased circulating renin level (HP:0000848)1.81075936
111Ventricular fibrillation (HP:0001663)1.80981572
112Volvulus (HP:0002580)1.80590215
113Elfin facies (HP:0004428)1.80501849
114Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.80072110
115Vaginal atresia (HP:0000148)1.79450277
116Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.79378042
117Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.78662735
118Short 4th metacarpal (HP:0010044)1.78662735
119Heterotopia (HP:0002282)1.78501366
120Exotropia (HP:0000577)1.77951607
121Impaired vibratory sensation (HP:0002495)1.77928800
122Status epilepticus (HP:0002133)1.76482538
123Aplasia involving bones of the extremities (HP:0009825)1.75771474
124Aplasia involving bones of the upper limbs (HP:0009823)1.75771474
125Aplasia of the phalanges of the hand (HP:0009802)1.75771474
126Congenital primary aphakia (HP:0007707)1.75769110
127Prolonged QT interval (HP:0001657)1.75232417
128Postural tremor (HP:0002174)1.74288172
129Obstructive sleep apnea (HP:0002870)1.74037311
130Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.73927119
131Nephrogenic diabetes insipidus (HP:0009806)1.73683324
132Craniofacial dystonia (HP:0012179)1.73518156
133Absent speech (HP:0001344)1.73227768
134Widely spaced teeth (HP:0000687)1.72440332
135Neoplasm of the heart (HP:0100544)1.71867904
136Fetal akinesia sequence (HP:0001989)1.70920305
137Hammertoe (HP:0001765)1.70920266
138Aplasia/Hypoplasia of the brainstem (HP:0007362)1.67981595
139Medial flaring of the eyebrow (HP:0010747)1.67025670
140Gastroesophageal reflux (HP:0002020)1.65462535
141Tented upper lip vermilion (HP:0010804)1.64136263
142Esotropia (HP:0000565)1.63951614
143Large earlobe (HP:0009748)1.63931267
144Chorioretinal atrophy (HP:0000533)1.63418947
145Broad ribs (HP:0000885)1.62018768

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.96812837
2NTRK33.66112661
3MAP3K93.50517873
4EPHA43.22601620
5MAP3K42.67604707
6MINK12.33750097
7NTRK22.33442067
8EPHA32.16836736
9BCR2.14265836
10PRKD32.07145310
11PAK62.06198672
12DAPK22.01001101
13CAMKK11.81005337
14NTRK11.79650240
15MAP2K71.78052323
16SIK21.71393319
17PHKG21.69460528
18PHKG11.69460528
19KSR21.61014613
20FRK1.58773484
21MAPK131.58651404
22MAP2K41.52228137
23KSR11.51837011
24TNIK1.50168861
25CDK51.49521763
26CAMK1G1.28935791
27MAP3K21.26431001
28TYRO31.25147571
29RET1.24039023
30UHMK11.17001274
31AKT31.16310006
32PRKCH1.14673228
33LMTK21.13839196
34STK381.13512327
35TRIM281.13009219
36SGK4941.12746656
37SGK2231.12746656
38CCNB11.10890432
39RIPK11.09186780
40PAK31.08095259
41PINK11.07093882
42SGK31.06826799
43CAMKK21.05188180
44FGFR21.04680581
45MAP4K21.03135749
46PRPF4B1.01414258
47SGK21.00421787
48TRIB30.98439714
49MARK20.98077552
50FES0.95937291
51CSNK1G20.93056682
52STK110.92144367
53PRKCG0.91450257
54ERBB30.91286012
55WNK30.88797452
56TAOK10.87609843
57SCYL20.86883879
58RIPK40.86714269
59PDGFRA0.85758728
60EPHB20.82884554
61CSNK1G10.82310714
62LATS20.82303126
63CSNK1G30.82035986
64PNCK0.79759464
65ALK0.77310127
66DYRK1A0.77242308
67SGK10.76946611
68PLK20.76298331
69CDC42BPA0.74907356
70CASK0.74887735
71DAPK10.73833937
72CAMK2A0.72383667
73WNK10.70375745
74CDK150.68219994
75OXSR10.67912059
76CDK180.67275140
77CAMK1D0.66833155
78PRKCZ0.65225410
79CDK140.65001739
80STK38L0.63715169
81CAMK10.61890111
82DMPK0.60639242
83BRD40.60620771
84PKN10.60415268
85FYN0.60097544
86GRK50.59489120
87ICK0.59238419
88ERBB20.57833202
89MAP3K70.57825095
90YES10.57438232
91MAP3K50.57405498
92MAP3K120.56908142
93RPS6KA20.56492202
94FER0.56437793
95PDK10.56123601
96CAMK2B0.55977852
97DYRK30.55772025
98PDPK10.55667413
99RPS6KA30.55511058
100INSRR0.55348279
101MAP3K130.54863275
102CDK11A0.54062690
103PDGFRB0.52863117
104PRKCE0.52445732
105CSNK1A1L0.49703586
106DYRK1B0.49520920
107DDR20.49220389
108PKN20.48412517
109PRKACB0.47903636
110MAPK100.47734735
111FGFR30.46117039
112CSNK1D0.44849444
113DYRK20.44617938
114WNK40.44405425
115PRKAA10.43997814
116MAP3K60.43158153
117ROCK10.42767838
118MUSK0.42701261
119CAMK40.41532860
120BMPR1B0.40263110
121RPS6KB10.39608643
122PRKG10.39352952
123RPS6KA40.38734625
124PTK20.38273824
125HIPK20.38065169
126CSNK1E0.35772458
127MAPK90.34685106
128LATS10.32422198
129CDK30.31918443
130MAPK80.31665925
131PRKACA0.29728624
132ADRBK20.29265830
133GSK3B0.29189443

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.79937820
2Synaptic vesicle cycle_Homo sapiens_hsa047212.50912521
3GABAergic synapse_Homo sapiens_hsa047272.35548022
4Circadian entrainment_Homo sapiens_hsa047132.30644764
5Olfactory transduction_Homo sapiens_hsa047402.20490917
6Glutamatergic synapse_Homo sapiens_hsa047242.18961480
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.13512889
8Long-term potentiation_Homo sapiens_hsa047202.11827576
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.11096660
10Morphine addiction_Homo sapiens_hsa050322.08809396
11Insulin secretion_Homo sapiens_hsa049111.90365745
12Dopaminergic synapse_Homo sapiens_hsa047281.87209000
13Amphetamine addiction_Homo sapiens_hsa050311.85573637
14Cholinergic synapse_Homo sapiens_hsa047251.79481945
15Salivary secretion_Homo sapiens_hsa049701.78514668
16Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.67750718
17Gastric acid secretion_Homo sapiens_hsa049711.67244720
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.63914147
19Type II diabetes mellitus_Homo sapiens_hsa049301.59528648
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.56950417
21Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.55540305
22Cocaine addiction_Homo sapiens_hsa050301.53651802
23Renin secretion_Homo sapiens_hsa049241.49513609
24Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.48143671
25Taste transduction_Homo sapiens_hsa047421.41879316
26Oxytocin signaling pathway_Homo sapiens_hsa049211.40721667
27Long-term depression_Homo sapiens_hsa047301.39729387
28Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.37844414
29Axon guidance_Homo sapiens_hsa043601.32676317
30GnRH signaling pathway_Homo sapiens_hsa049121.32038644
31Serotonergic synapse_Homo sapiens_hsa047261.30211571
32Gap junction_Homo sapiens_hsa045401.27532010
33Nitrogen metabolism_Homo sapiens_hsa009101.22635594
34Glioma_Homo sapiens_hsa052141.21387129
35Calcium signaling pathway_Homo sapiens_hsa040201.20185473
36Estrogen signaling pathway_Homo sapiens_hsa049151.19929069
37Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.18078453
38cAMP signaling pathway_Homo sapiens_hsa040241.17055001
39Phosphatidylinositol signaling system_Homo sapiens_hsa040701.13611442
40ErbB signaling pathway_Homo sapiens_hsa040121.12211272
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.11840064
42Dorso-ventral axis formation_Homo sapiens_hsa043201.06833480
43Carbohydrate digestion and absorption_Homo sapiens_hsa049731.03937717
44cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01683623
45Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.00730636
46Endometrial cancer_Homo sapiens_hsa052130.93908844
47Phospholipase D signaling pathway_Homo sapiens_hsa040720.93125038
48Melanogenesis_Homo sapiens_hsa049160.92679865
49Dilated cardiomyopathy_Homo sapiens_hsa054140.90150477
50mTOR signaling pathway_Homo sapiens_hsa041500.85960502
51Pancreatic secretion_Homo sapiens_hsa049720.84869502
52Ether lipid metabolism_Homo sapiens_hsa005650.84230101
53Hedgehog signaling pathway_Homo sapiens_hsa043400.82311845
54Thyroid hormone synthesis_Homo sapiens_hsa049180.81266796
55Choline metabolism in cancer_Homo sapiens_hsa052310.81123184
56Collecting duct acid secretion_Homo sapiens_hsa049660.80646810
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.80308999
58Thyroid hormone signaling pathway_Homo sapiens_hsa049190.79568996
59Steroid biosynthesis_Homo sapiens_hsa001000.76950534
60* Neurotrophin signaling pathway_Homo sapiens_hsa047220.74694721
61Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.74190957
62Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.73919401
63Bile secretion_Homo sapiens_hsa049760.72746794
64Renal cell carcinoma_Homo sapiens_hsa052110.72170104
65MAPK signaling pathway_Homo sapiens_hsa040100.71222807
66Hippo signaling pathway_Homo sapiens_hsa043900.71007358
67Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.69868047
68Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.68833208
69Regulation of autophagy_Homo sapiens_hsa041400.67954846
70Non-small cell lung cancer_Homo sapiens_hsa052230.67844629
71VEGF signaling pathway_Homo sapiens_hsa043700.67363942
72Insulin signaling pathway_Homo sapiens_hsa049100.66728112
73Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64575997
74Phototransduction_Homo sapiens_hsa047440.63101705
75Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.62946415
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.62722562
77Glucagon signaling pathway_Homo sapiens_hsa049220.62696885
78Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.62506668
79Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.61999268
80Rap1 signaling pathway_Homo sapiens_hsa040150.60758667
81Vibrio cholerae infection_Homo sapiens_hsa051100.60420114
82Colorectal cancer_Homo sapiens_hsa052100.59320626
83Ras signaling pathway_Homo sapiens_hsa040140.58776991
84Sphingolipid signaling pathway_Homo sapiens_hsa040710.58443326
85Endocytosis_Homo sapiens_hsa041440.57622562
86Tight junction_Homo sapiens_hsa045300.56666466
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.55999300
88FoxO signaling pathway_Homo sapiens_hsa040680.55477514
89Inositol phosphate metabolism_Homo sapiens_hsa005620.54897614
90Circadian rhythm_Homo sapiens_hsa047100.54067036
91Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51488514
92Adherens junction_Homo sapiens_hsa045200.50287669
93Butanoate metabolism_Homo sapiens_hsa006500.50010232
94Oocyte meiosis_Homo sapiens_hsa041140.49145355
95Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.48447291
96Insulin resistance_Homo sapiens_hsa049310.47706301
97Prolactin signaling pathway_Homo sapiens_hsa049170.47482872
98Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.47338202
99Basal cell carcinoma_Homo sapiens_hsa052170.47219333
100Cardiac muscle contraction_Homo sapiens_hsa042600.46117707
101Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.45113321
102Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44392782
103Chemokine signaling pathway_Homo sapiens_hsa040620.43812759
104Fatty acid biosynthesis_Homo sapiens_hsa000610.43593432
105Prion diseases_Homo sapiens_hsa050200.43552177
106Wnt signaling pathway_Homo sapiens_hsa043100.43488337
107Melanoma_Homo sapiens_hsa052180.43148393
108Alcoholism_Homo sapiens_hsa050340.41825350
109Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.41229418
110AMPK signaling pathway_Homo sapiens_hsa041520.40897636
111Ovarian steroidogenesis_Homo sapiens_hsa049130.39369148
112Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38768395
113Focal adhesion_Homo sapiens_hsa045100.38372680
114Central carbon metabolism in cancer_Homo sapiens_hsa052300.37827074
115Proteoglycans in cancer_Homo sapiens_hsa052050.36893136

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