KIF13A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)6.65289303
2cardiac myofibril assembly (GO:0055003)6.58566588
3myofibril assembly (GO:0030239)6.01481152
4negative regulation of potassium ion transmembrane transporter activity (GO:1901017)5.92785846
5actin-myosin filament sliding (GO:0033275)5.78194135
6muscle filament sliding (GO:0030049)5.78194135
7negative regulation of potassium ion transmembrane transport (GO:1901380)5.27853679
8plasma membrane repair (GO:0001778)5.25200898
9regulation of skeletal muscle contraction (GO:0014819)5.19882620
10actin-mediated cell contraction (GO:0070252)4.93265131
11positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)4.84009012
12actomyosin structure organization (GO:0031032)4.76015958
13cardiac muscle contraction (GO:0060048)4.69190134
14regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO4.64096545
15bundle of His cell to Purkinje myocyte communication (GO:0086069)4.64036226
16regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)4.57078646
17cardiac muscle cell development (GO:0055013)4.54487323
18regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.32442281
19ventricular cardiac muscle cell action potential (GO:0086005)4.32038983
20cardiac cell development (GO:0055006)4.30795073
21regulation of actin filament-based movement (GO:1903115)4.29254737
22carnitine shuttle (GO:0006853)4.22019297
23cardiac muscle tissue morphogenesis (GO:0055008)4.21710351
24ventricular cardiac muscle tissue morphogenesis (GO:0055010)4.08523309
25actin filament-based movement (GO:0030048)4.07881084
26adult heart development (GO:0007512)4.02184882
27regulation of sarcomere organization (GO:0060297)4.02164115
28regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)3.98549977
29negative regulation of protein localization to cell surface (GO:2000009)3.97866031
30regulation of cardioblast differentiation (GO:0051890)3.95361967
31heart trabecula formation (GO:0060347)3.95294736
32striated muscle contraction (GO:0006941)3.94990169
33cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.89783354
34creatine metabolic process (GO:0006600)3.89643575
35muscle tissue morphogenesis (GO:0060415)3.88169177
36cardiac muscle hypertrophy (GO:0003300)3.88069791
37cell communication involved in cardiac conduction (GO:0086065)3.86118001
38sarcoplasmic reticulum calcium ion transport (GO:0070296)3.83311666
39regulation of relaxation of muscle (GO:1901077)3.77747983
40fatty acid transmembrane transport (GO:1902001)3.77722380
41striated muscle hypertrophy (GO:0014897)3.73643605
42regulation of membrane repolarization (GO:0060306)3.63348568
43regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)3.62064117
44tricarboxylic acid cycle (GO:0006099)3.54530970
45regulation of cell communication by electrical coupling (GO:0010649)3.53523154
46regulation of striated muscle contraction (GO:0006942)3.51321628
47hemidesmosome assembly (GO:0031581)3.42098229
48cell communication by electrical coupling (GO:0010644)3.35573638
49regulation of the force of heart contraction (GO:0002026)3.27656537
50muscle hypertrophy (GO:0014896)3.22214827
51cardiac muscle cell action potential (GO:0086001)3.20573322
52cardiac muscle cell action potential involved in contraction (GO:0086002)3.17772642
53desmosome organization (GO:0002934)3.16667176
54regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.15855523
55carnitine transmembrane transport (GO:1902603)3.12917425
56response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.06443645
57cytoskeletal anchoring at plasma membrane (GO:0007016)3.05117732
58regulation of p38MAPK cascade (GO:1900744)3.03063774
59focal adhesion assembly (GO:0048041)3.01225513
60cell-substrate adherens junction assembly (GO:0007045)3.01225513
61positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.98285521
62regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.97893203
63regulation of cardiac muscle cell contraction (GO:0086004)2.97057056
64regulation of heart rate by cardiac conduction (GO:0086091)2.97007518
65macroautophagy (GO:0016236)2.95497319
66cardiac conduction (GO:0061337)2.95050695
67membrane tubulation (GO:0097320)2.94070426
68hypotonic response (GO:0006971)2.93157104
69muscle contraction (GO:0006936)2.92481919
70negative regulation of cytosolic calcium ion concentration (GO:0051481)2.91739183
71skeletal muscle contraction (GO:0003009)2.90759580
72relaxation of cardiac muscle (GO:0055119)2.90632124
73skeletal muscle adaptation (GO:0043501)2.87916646
74skin morphogenesis (GO:0043589)2.85020613
75adherens junction assembly (GO:0034333)2.84886751
76carnitine transport (GO:0015879)2.83287657
77amino-acid betaine transport (GO:0015838)2.83287657
78regulation of heart rate (GO:0002027)2.82619427
79cardiac muscle hypertrophy in response to stress (GO:0014898)2.82030340
80muscle hypertrophy in response to stress (GO:0003299)2.82030340
81cardiac muscle adaptation (GO:0014887)2.82030340
82response to muscle activity (GO:0014850)2.80592513
83trabecula formation (GO:0060343)2.79646212
84cell adhesion mediated by integrin (GO:0033627)2.79084096
85response to inactivity (GO:0014854)2.79079041
86epithelial cell-cell adhesion (GO:0090136)2.78565752
87regulation of cardiac muscle contraction (GO:0055117)2.78055745
88endodermal cell differentiation (GO:0035987)2.73539844
89negative regulation of fatty acid transport (GO:2000192)2.73195870
90striated muscle adaptation (GO:0014888)2.71550197
91muscle system process (GO:0003012)2.70031116
92potassium ion import (GO:0010107)2.69104821
93striated muscle cell development (GO:0055002)2.68478691
94insulin-like growth factor receptor signaling pathway (GO:0048009)2.67697787
95cellular response to epinephrine stimulus (GO:0071872)2.66351404
96cell-substrate junction assembly (GO:0007044)2.65767621
97heart process (GO:0003015)2.65548997
98heart contraction (GO:0060047)2.65548997
99regulation of acyl-CoA biosynthetic process (GO:0050812)2.64948282
100negative regulation of striated muscle cell apoptotic process (GO:0010664)2.63792556
101gap junction assembly (GO:0016264)2.63572285
102glomerular filtration (GO:0003094)2.62631961
103regulation of calcium ion transmembrane transporter activity (GO:1901019)2.62614132
104regulation of calcium ion transmembrane transport (GO:1903169)2.62614132
105negative regulation of potassium ion transport (GO:0043267)2.62582596
106protein localization to endosome (GO:0036010)2.62463673
107renal filtration (GO:0097205)2.61778598
108regulation of sequestering of triglyceride (GO:0010889)2.59704406
109regulation of heart contraction (GO:0008016)2.57878800
110negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.57716101
111basement membrane organization (GO:0071711)2.57381614
112heart morphogenesis (GO:0003007)2.55013417
113positive regulation of receptor recycling (GO:0001921)2.53794255
114intracellular lipid transport (GO:0032365)2.51106679
115import into cell (GO:0098657)2.50343419
116outflow tract septum morphogenesis (GO:0003148)2.47510583
117positive regulation of cation channel activity (GO:2001259)2.45911694
118response to epinephrine (GO:0071871)2.44072085
119glycogen catabolic process (GO:0005980)2.42468885
120iron ion import (GO:0097286)2.42299272
121cell migration involved in heart development (GO:0060973)2.41363690
122endocardial cushion development (GO:0003197)2.39704384
123positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.39537832
124striated muscle atrophy (GO:0014891)2.39355508
125glucan catabolic process (GO:0009251)2.39175170
126sequestering of extracellular ligand from receptor (GO:0035581)2.37795127
127myoblast fusion (GO:0007520)2.36612618
128paraxial mesoderm development (GO:0048339)2.33468860
129cellular polysaccharide catabolic process (GO:0044247)2.33088273
130regulation of transforming growth factor beta2 production (GO:0032909)2.31834333
131surfactant homeostasis (GO:0043129)2.31151702
132retina vasculature morphogenesis in camera-type eye (GO:0061299)2.29141888
133atrioventricular valve morphogenesis (GO:0003181)2.28753416
134collagen fibril organization (GO:0030199)2.27750029
135syncytium formation by plasma membrane fusion (GO:0000768)2.24829063
136regulation of tight junction assembly (GO:2000810)2.24151505
137positive regulation of myotube differentiation (GO:0010831)2.23436607
138skeletal muscle tissue development (GO:0007519)2.20387988
139positive regulation of osteoblast proliferation (GO:0033690)2.20065958
140negative regulation of vascular permeability (GO:0043116)2.18445911
141negative regulation of complement activation (GO:0045916)2.17933230
142chemical homeostasis within a tissue (GO:0048875)2.17320711
143skeletal muscle fiber development (GO:0048741)2.15478795
144extracellular matrix assembly (GO:0085029)2.15258798
145regulation of skeletal muscle cell differentiation (GO:2001014)2.14656437

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.63428386
2EP300_21415370_ChIP-Seq_HL-1_Mouse3.33003855
3TP63_17297297_ChIP-ChIP_HaCaT_Human2.87647929
4TBX20_22328084_ChIP-Seq_HEART_Mouse2.66961139
5TBX20_22080862_ChIP-Seq_HEART_Mouse2.66961139
6TRIM28_21343339_ChIP-Seq_HEK293_Human2.52634837
7ESR1_20079471_ChIP-ChIP_T-47D_Human2.49670318
8ZNF263_19887448_ChIP-Seq_K562_Human2.34342121
9EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.31090462
10ESR2_21235772_ChIP-Seq_MCF-7_Human2.15680335
11CLOCK_20551151_ChIP-Seq_293T_Human2.11890364
12CDX2_19796622_ChIP-Seq_MESCs_Mouse2.10542359
13RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.07500146
14RARG_19884340_ChIP-ChIP_MEFs_Mouse2.00963357
15SMAD_19615063_ChIP-ChIP_OVARY_Human2.00357020
16NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.99581582
17CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.98852917
18ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.94159347
19SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.91673624
20TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.77607526
21TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73492749
22SOX9_24532713_ChIP-Seq_HFSC_Mouse1.67156260
23DROSHA_22980978_ChIP-Seq_HELA_Human1.64380541
24NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.63857282
25ISL1_27105846_Chip-Seq_CPCs_Mouse1.57036552
26CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.56891090
27PPAR_26484153_Chip-Seq_NCI-H1993_Human1.55205527
28FOXO3_23340844_ChIP-Seq_DLD1_Human1.55167844
29Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.55134562
30TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.54830022
31MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.54601038
32ESR1_21235772_ChIP-Seq_MCF-7_Human1.53403095
33KDM2B_26808549_Chip-Seq_SUP-B15_Human1.53296670
34WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.51344367
35ZNF217_24962896_ChIP-Seq_MCF-7_Human1.50338682
36TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.50284461
37BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.46280415
38BRD4_25478319_ChIP-Seq_HGPS_Human1.44622304
39CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.42993708
40PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.41454308
41KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.40492293
42GATA2_21666600_ChIP-Seq_HMVEC_Human1.39819694
43* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.38493572
44TP53_16413492_ChIP-PET_HCT116_Human1.38033687
45STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.37476376
46HIF1A_21447827_ChIP-Seq_MCF-7_Human1.35398166
47KDM2B_26808549_Chip-Seq_K562_Human1.34228277
48* FOXA2_19822575_ChIP-Seq_HepG2_Human1.31614662
49KDM2B_26808549_Chip-Seq_DND41_Human1.31206339
50AHR_22903824_ChIP-Seq_MCF-7_Human1.31123940
51CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.28579658
52RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.28378548
53* CJUN_26792858_Chip-Seq_BT549_Human1.28286679
54STAT6_21828071_ChIP-Seq_BEAS2B_Human1.26521639
55ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24912173
56P300_27058665_Chip-Seq_ZR-75-30cells_Human1.24677303
57CTNNB1_20460455_ChIP-Seq_HCT116_Human1.23187897
58ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.21483638
59SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.20711237
60* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.19306098
61* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.18119337
62RACK7_27058665_Chip-Seq_MCF-7_Human1.17459870
63LXR_22158963_ChIP-Seq_LIVER_Mouse1.16877350
64ZFP281_18757296_ChIP-ChIP_E14_Mouse1.15988640
65SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.15306000
66RUNX1_27514584_Chip-Seq_MCF-7_Human1.13905194
67PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.12287493
68SOX2_27498859_Chip-Seq_STOMACH_Mouse1.12003810
69SMAD3_21741376_ChIP-Seq_HESCs_Human1.11838021
70* TP63_23658742_ChIP-Seq_EP156T_Human1.11355704
71AR_21572438_ChIP-Seq_LNCaP_Human1.10176404
72RNF2_18974828_ChIP-Seq_MESCs_Mouse1.09797075
73EZH2_18974828_ChIP-Seq_MESCs_Mouse1.09797075
74SALL4_18804426_ChIP-ChIP_XEN_Mouse1.09222321
75ARNT_22903824_ChIP-Seq_MCF-7_Human1.07997238
76ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.07971902
77THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.07469389
78P63_26484246_Chip-Seq_KERATINOCYTES_Human1.06703378
79PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.05888105
80NFIB_24661679_ChIP-Seq_LUNG_Mouse1.04812325
81NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.04362726
82FOXM1_26456572_ChIP-Seq_MCF-7_Human1.04065976
83ELK3_25401928_ChIP-Seq_HUVEC_Human1.03817942
84* GATA1_19941826_ChIP-Seq_K562_Human1.03354177
85TCF4_18268006_ChIP-ChIP_LS174T_Human1.03236628
86NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.02849699
87UBF1/2_26484160_Chip-Seq_HMECs_Human1.01841279
88TP53_18474530_ChIP-ChIP_U2OS_Human1.01738757
89WT1_19549856_ChIP-ChIP_CCG9911_Human1.01634732
90* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.01398606
91MTF2_20144788_ChIP-Seq_MESCs_Mouse1.01335292
92RXR_22158963_ChIP-Seq_LIVER_Mouse1.01146252
93NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.99577274
94NRF2_20460467_ChIP-Seq_MEFs_Mouse0.99577274
95CDX2_20551321_ChIP-Seq_CACO-2_Human0.99288249
96FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.98906179
97YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98519764
98BP1_19119308_ChIP-ChIP_Hs578T_Human0.98458453
99PIAS1_25552417_ChIP-Seq_VCAP_Human0.98070983
100SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.97703837
101* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96745160
102SOX2_20726797_ChIP-Seq_SW620_Human0.96407686
103GATA4_21415370_ChIP-Seq_HL-1_Mouse0.95535354
104KDM2B_26808549_Chip-Seq_JURKAT_Human0.95515413
105SMAD4_21741376_ChIP-Seq_HESCs_Human0.95493739
106ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.95380581
107PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.94053432
108ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.93906498
109SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92860877
110GATA1_22025678_ChIP-Seq_K562_Human0.92286709
111ZFP281_27345836_Chip-Seq_ESCs_Mouse0.91864715
112CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.90717928
113* SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.90277472
114ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.88774873
115SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.88551904
116* TP53_23651856_ChIP-Seq_MEFs_Mouse0.88320105
117FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.88013481
118SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.86778355
119SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.86778355
120* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.85370192
121* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.85220014
122FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.84999839
123AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.84165315
124MYB_21317192_ChIP-Seq_ERMYB_Mouse0.82763177
125* GATA2_19941826_ChIP-Seq_K562_Human0.81383399
126FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.81335097

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004084_abnormal_cardiac_muscle4.76332514
2MP0002837_dystrophic_cardiac_calcinosis4.67934043
3MP0000751_myopathy4.57810002
4MP0004036_abnormal_muscle_relaxation3.82663286
5MP0004215_abnormal_myocardial_fiber3.54085248
6MP0000749_muscle_degeneration3.48960277
7MP0003646_muscle_fatigue3.44653511
8MP0005330_cardiomyopathy3.10938289
9MP0003950_abnormal_plasma_membrane3.01969289
10MP0004087_abnormal_muscle_fiber2.96753343
11MP0004145_abnormal_muscle_electrophysio2.74116656
12MP0008775_abnormal_heart_ventricle2.60186585
13MP0002972_abnormal_cardiac_muscle2.55253877
14MP0010630_abnormal_cardiac_muscle2.42531735
15MP0005620_abnormal_muscle_contractility2.41968571
16MP0000750_abnormal_muscle_regeneration2.37810224
17MP0004130_abnormal_muscle_cell2.33319973
18MP0002106_abnormal_muscle_physiology2.30898828
19MP0003137_abnormal_impulse_conducting2.27599013
20MP0003705_abnormal_hypodermis_morpholog2.17344948
21MP0006138_congestive_heart_failure2.13369894
22MP0000747_muscle_weakness2.12129013
23MP0001544_abnormal_cardiovascular_syste2.10464709
24MP0005385_cardiovascular_system_phenoty2.10464709
25MP0002269_muscular_atrophy2.00238308
26MP0000759_abnormal_skeletal_muscle1.95882516
27MP0005369_muscle_phenotype1.95548232
28MP0004272_abnormal_basement_membrane1.94779686
29MP0003828_pulmonary_edema1.92320318
30MP0008438_abnormal_cutaneous_collagen1.91579412
31MP0005451_abnormal_body_composition1.90822580
32MP0010368_abnormal_lymphatic_system1.89155475
33MP0005409_darkened_coat_color1.84653883
34MP0004233_abnormal_muscle_weight1.77586138
35MP0004484_altered_response_of1.77467717
36MP0005503_abnormal_tendon_morphology1.69470940
37MP0004085_abnormal_heartbeat1.65315258
38MP0005666_abnormal_adipose_tissue1.65118585
39MP0004185_abnormal_adipocyte_glucose1.61125107
40MP0005257_abnormal_intraocular_pressure1.56328880
41MP0003566_abnormal_cell_adhesion1.54427634
42MP0000733_abnormal_muscle_development1.53384161
43MP0005623_abnormal_meninges_morphology1.51558082
44MP0003221_abnormal_cardiomyocyte_apopto1.47580712
45MP0005023_abnormal_wound_healing1.42599630
46MP0005275_abnormal_skin_tensile1.42052274
47MP0005375_adipose_tissue_phenotype1.34525808
48MP0002896_abnormal_bone_mineralization1.32632351
49MP0003191_abnormal_cellular_cholesterol1.31039738
50MP0003279_aneurysm1.29551567
51MP0003453_abnormal_keratinocyte_physiol1.27910370
52MP0002108_abnormal_muscle_morphology1.27892884
53MP0003567_abnormal_fetal_cardiomyocyte1.24493796
54MP0002796_impaired_skin_barrier1.22711246
55MP0002127_abnormal_cardiovascular_syste1.18637840
56MP0005670_abnormal_white_adipose1.16280644
57MP0002234_abnormal_pharynx_morphology1.14631285
58MP0002332_abnormal_exercise_endurance1.12119519
59MP0004510_myositis1.10840866
60MP0000266_abnormal_heart_morphology1.09869882
61MP0001879_abnormal_lymphatic_vessel1.08239810
62MP0000003_abnormal_adipose_tissue1.06222978
63MP0001958_emphysema1.05061606
64MP0005076_abnormal_cell_differentiation1.02098109
65MP0001661_extended_life_span1.00426131
66MP0009384_cardiac_valve_regurgitation0.99651515
67MP0000537_abnormal_urethra_morphology0.97476377
68MP0005248_abnormal_Harderian_gland0.96034808
69MP0006054_spinal_hemorrhage0.93412895
70MP0010678_abnormal_skin_adnexa0.93407492
71MP0000569_abnormal_digit_pigmentation0.92502210
72MP0002128_abnormal_blood_circulation0.89118752
73MP0000920_abnormal_myelination0.86544886
74MP0005595_abnormal_vascular_smooth0.85085246
75MP0005171_absent_coat_pigmentation0.83485197
76MP0000343_altered_response_to0.82585454
77MP0004858_abnormal_nervous_system0.82352251
78MP0003300_gastrointestinal_ulcer0.82015241
79MP0002925_abnormal_cardiovascular_devel0.81139715
80MP0010030_abnormal_orbit_morphology0.80596783
81MP0000428_abnormal_craniofacial_morphol0.77206727
82MP0000383_abnormal_hair_follicle0.76879472
83MP0000767_abnormal_smooth_muscle0.75979916
84MP0001915_intracranial_hemorrhage0.75081467
85MP0009840_abnormal_foam_cell0.74206425
86MP0000762_abnormal_tongue_morphology0.73680654
87MP0005058_abnormal_lysosome_morphology0.72786740
88MP0002998_abnormal_bone_remodeling0.71826365
89MP0001849_ear_inflammation0.70415292
90MP0008260_abnormal_autophagy0.69598160
91MP0005164_abnormal_response_to0.69564787
92MP0001299_abnormal_eye_distance/0.69507516
93MP0005165_increased_susceptibility_to0.69127068
94MP0001542_abnormal_bone_strength0.69020367
95MP0002133_abnormal_respiratory_system0.68782548
96MP0005388_respiratory_system_phenotype0.68782548
97MP0000462_abnormal_digestive_system0.67823642
98MP0003941_abnormal_skin_development0.67764070
99MP0002090_abnormal_vision0.66593692
100MP0001614_abnormal_blood_vessel0.65861656
101MP0000534_abnormal_ureter_morphology0.64926014
102MP0003045_fibrosis0.64407680
103MP0002168_other_aberrant_phenotype0.64248381
104MP0005551_abnormal_eye_electrophysiolog0.64175548
105MP0008961_abnormal_basal_metabolism0.64066591
106MP0005187_abnormal_penis_morphology0.63146352
107MP0009780_abnormal_chondrocyte_physiolo0.63053669
108MP0000579_abnormal_nail_morphology0.62258341
109MP0005167_abnormal_blood-brain_barrier0.59598983
110MP0004043_abnormal_pH_regulation0.59461190
111MP0010234_abnormal_vibrissa_follicle0.56955472
112MP0010352_gastrointestinal_tract_polyps0.56164491
113MP0003011_delayed_dark_adaptation0.56064894
114MP0006072_abnormal_retinal_apoptosis0.55810482
115MP0003690_abnormal_glial_cell0.55804341
116MP0002971_abnormal_brown_adipose0.54950856
117MP0001784_abnormal_fluid_regulation0.53974387
118MP0006036_abnormal_mitochondrial_physio0.53596251
119MP0000013_abnormal_adipose_tissue0.52761006
120MP0003091_abnormal_cell_migration0.52488918
121MP0002877_abnormal_melanocyte_morpholog0.52236154
122MP0003935_abnormal_craniofacial_develop0.52087732
123MP0000230_abnormal_systemic_arterial0.51854158
124MP0000467_abnormal_esophagus_morphology0.51443997
125MP0002060_abnormal_skin_morphology0.51261543
126MP0002295_abnormal_pulmonary_circulatio0.50227345
127MP0003634_abnormal_glial_cell0.49893259

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)6.36260749
2Exercise-induced muscle cramps (HP:0003710)5.64838002
3Muscle fiber splitting (HP:0003555)5.55904149
4Ventricular tachycardia (HP:0004756)5.49084295
5Hyporeflexia of lower limbs (HP:0002600)5.43738107
6Exercise-induced myalgia (HP:0003738)5.40408601
7Calf muscle hypertrophy (HP:0008981)5.14255989
8Right ventricular cardiomyopathy (HP:0011663)4.99929230
9Muscle hypertrophy of the lower extremities (HP:0008968)4.94735112
10Atrial fibrillation (HP:0005110)4.73336434
11Abnormality of the calf musculature (HP:0001430)4.68289597
12Primary atrial arrhythmia (HP:0001692)4.34434832
13Difficulty running (HP:0009046)4.32072946
14Abnormality of the left ventricular outflow tract (HP:0011103)4.28883142
15Subaortic stenosis (HP:0001682)4.28883142
16Lipoatrophy (HP:0100578)4.23006493
17Increased connective tissue (HP:0009025)4.20045391
18Supraventricular tachycardia (HP:0004755)4.13717084
19Supraventricular arrhythmia (HP:0005115)4.11396390
20Myoglobinuria (HP:0002913)3.96189657
21EMG: myopathic abnormalities (HP:0003458)3.94671685
22Type 1 muscle fiber predominance (HP:0003803)3.85021160
23Protrusio acetabuli (HP:0003179)3.80032708
24Syncope (HP:0001279)3.79567328
25Prolonged QT interval (HP:0001657)3.65326668
26Muscle fiber inclusion bodies (HP:0100299)3.60672543
27Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)3.54444765
28Dilated cardiomyopathy (HP:0001644)3.52495316
29Ventricular arrhythmia (HP:0004308)3.44559278
30Broad metatarsal (HP:0001783)3.35341213
31Bundle branch block (HP:0011710)3.27956682
32Premature rupture of membranes (HP:0001788)3.13404726
33Asymmetric septal hypertrophy (HP:0001670)3.11687045
34Aortic aneurysm (HP:0004942)3.11022201
35Ventricular fibrillation (HP:0001663)3.08980514
36Increased variability in muscle fiber diameter (HP:0003557)3.05433936
37Palpitations (HP:0001962)2.98799644
38Nemaline bodies (HP:0003798)2.95418584
39Scapular winging (HP:0003691)2.92414893
40Arterial tortuosity (HP:0005116)2.88856443
41Vascular tortuosity (HP:0004948)2.88346750
42Myotonia (HP:0002486)2.84963366
43Abnormality of skeletal muscle fiber size (HP:0012084)2.81406992
44Heart block (HP:0012722)2.74516431
45Rhabdomyolysis (HP:0003201)2.73629642
46Difficulty climbing stairs (HP:0003551)2.70690883
47Ulnar deviation of the wrist (HP:0003049)2.68754148
48Central scotoma (HP:0000603)2.67700811
49Atrioventricular block (HP:0001678)2.66869239
50Abnormal atrioventricular conduction (HP:0005150)2.64329516
51Mildly elevated creatine phosphokinase (HP:0008180)2.59858810
52Aortic dissection (HP:0002647)2.58913884
53Neck muscle weakness (HP:0000467)2.57402949
54Muscle stiffness (HP:0003552)2.56294991
55Hypoplastic ischia (HP:0003175)2.44932289
56Abnormal EKG (HP:0003115)2.42529751
57Abnormality of the foot musculature (HP:0001436)2.35368546
58Osteolytic defects of the phalanges of the hand (HP:0009771)2.35161409
59Osteolytic defects of the hand bones (HP:0009699)2.35161409
60Round ear (HP:0100830)2.29815184
61Foot dorsiflexor weakness (HP:0009027)2.25947730
62Distal lower limb muscle weakness (HP:0009053)2.24122088
63Fragile skin (HP:0001030)2.22830106
64Shallow orbits (HP:0000586)2.20199767
65Gowers sign (HP:0003391)2.19446739
66Limb-girdle muscle atrophy (HP:0003797)2.14656518
67Centrally nucleated skeletal muscle fibers (HP:0003687)2.13664075
68Mitral stenosis (HP:0001718)2.12873190
69Spinal rigidity (HP:0003306)2.12483376
70Abnormality of the ischium (HP:0003174)2.12196119
71Cerebral aneurysm (HP:0004944)2.10767271
72Palmoplantar keratoderma (HP:0000982)2.08281563
73Wormian bones (HP:0002645)2.06814894
74Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.06547969
75Slender build (HP:0001533)2.05796258
76Distal lower limb amyotrophy (HP:0008944)2.04591379
77Overgrowth (HP:0001548)2.03886846
78Calcaneovalgus deformity (HP:0001848)2.01928089
79Cervical subluxation (HP:0003308)2.00600541
80Limited hip movement (HP:0008800)2.00093036
81Scotoma (HP:0000575)1.97293235
82Lymphangioma (HP:0100764)1.97095280
83Proximal amyotrophy (HP:0007126)1.96525310
84Muscular dystrophy (HP:0003560)1.95541059
85Vertebral compression fractures (HP:0002953)1.92287132
86Frequent falls (HP:0002359)1.90594834
87Hamartoma of the eye (HP:0010568)1.90460519
88Mitral valve prolapse (HP:0001634)1.89535525
89Sudden cardiac death (HP:0001645)1.89084801
90Dilatation of the ascending aorta (HP:0005111)1.87489754
91Dysmetric saccades (HP:0000641)1.86247376
92Lower limb amyotrophy (HP:0007210)1.85788488
93Abnormality of the salivary glands (HP:0010286)1.84903274
94Peritonitis (HP:0002586)1.84412173
95Distal arthrogryposis (HP:0005684)1.83925477
96Rimmed vacuoles (HP:0003805)1.83553283
97EMG: neuropathic changes (HP:0003445)1.83325652
98Bladder diverticulum (HP:0000015)1.81541174
99Hip contracture (HP:0003273)1.78963531
100Advanced eruption of teeth (HP:0006288)1.77253773
101Myopathic facies (HP:0002058)1.77114602
102Deformed tarsal bones (HP:0008119)1.76027852
103Cardiovascular calcification (HP:0011915)1.75656588
104Abnormality of the calcaneus (HP:0008364)1.73473273
105Hypoplasia of the iris (HP:0007676)1.73228831
106Left ventricular hypertrophy (HP:0001712)1.72042617
107Limb-girdle muscle weakness (HP:0003325)1.70718337
108Natal tooth (HP:0000695)1.69390353
109Abnormality of the shoulder girdle musculature (HP:0001435)1.69387101
110Aneurysm (HP:0002617)1.68888067
111Pulmonary artery stenosis (HP:0004415)1.67796059
112Milia (HP:0001056)1.66903992
113Ankle contracture (HP:0006466)1.64952690
114Ketoacidosis (HP:0001993)1.64589958
115Visceral angiomatosis (HP:0100761)1.63724099
116Generalized muscle weakness (HP:0003324)1.61218842
117Rectal prolapse (HP:0002035)1.59757162
118Mitral regurgitation (HP:0001653)1.59657268
119Vertebral arch anomaly (HP:0008438)1.59605474
120Soft skin (HP:0000977)1.59496161
121Atrophic scars (HP:0001075)1.58928869
122Congestive heart failure (HP:0001635)1.55842437
123Hemangiomatosis (HP:0007461)1.55319934
124Rapidly progressive (HP:0003678)1.54772245
125Ankyloglossia (HP:0010296)1.54632404
126Achilles tendon contracture (HP:0001771)1.54587634
127Insidious onset (HP:0003587)1.54269199
128Termporal pattern (HP:0011008)1.54269199
129Flat acetabular roof (HP:0003180)1.52941800
130Conjunctival hamartoma (HP:0100780)1.52006121
131Pigmentary retinal degeneration (HP:0001146)1.50517771
132Facial diplegia (HP:0001349)1.50423146
133Hypoglycemic coma (HP:0001325)1.48688962
134Areflexia of lower limbs (HP:0002522)1.48661505
135Steppage gait (HP:0003376)1.48235825

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.93774883
2OBSCN4.10841068
3DMPK3.29742400
4PHKG23.26009187
5PHKG13.26009187
6LMTK23.19504035
7PKN22.64081995
8TRIB32.52918562
9EPHB12.32776445
10RIPK12.28803783
11MYLK2.11423415
12STK391.86347952
13PIK3CA1.84459768
14TIE11.81049967
15NEK11.80135103
16NEK91.76029742
17AKT31.69580534
18LATS11.65717063
19CAMK1D1.60946406
20PDK31.52804137
21PDK41.52804137
22MAP3K21.47034355
23CAMK1G1.41129521
24FGFR21.37370115
25PTK61.35302683
26STK241.34536927
27PRKD11.32475680
28MET1.30936962
29ICK1.24656976
30MAP3K71.23301293
31CDK121.22863742
32ILK1.22485186
33TRPM71.20716712
34MAP3K61.20613562
35PAK31.16481713
36PDGFRA1.15206768
37WNK11.12634634
38PDK21.10205985
39CAMK2D1.09073303
40NTRK11.06509043
41PKN11.06241623
42FGFR31.04884922
43MAPK71.04316255
44ERN11.03599883
45MOS1.03206072
46ROCK21.02676159
47SGK31.02326365
48ROCK11.02317920
49SIK11.01700038
50FGFR40.97683120
51PBK0.96949142
52PINK10.95856916
53WNK40.93395284
54MUSK0.93282167
55MAP3K100.89853720
56CDC42BPA0.88772657
57FER0.87994420
58PRKAA20.86726585
59BCKDK0.84835929
60TGFBR20.84031928
61MAP3K10.82711771
62INSRR0.80490002
63PRPF4B0.76826020
64LIMK10.75553367
65LRRK20.75123924
66EPHA30.74630640
67MTOR0.72696163
68PRKAA10.72408604
69DDR20.72243138
70PAK60.72220401
71BMX0.71918362
72EPHB20.71731620
73MAPK120.70562962
74SGK20.70462307
75MAP2K30.70365414
76PAK20.68605589
77MAP2K10.67709500
78PDGFRB0.66799935
79EEF2K0.65863231
80PAK40.64369576
81PRKD20.64030332
82MAP3K30.62721760
83MAP2K40.60899748
84FGFR10.58313224
85CAMK40.56036565
86ERBB20.55573761
87JAK10.53831025
88DYRK1B0.52194560
89MAPKAPK30.51538952
90ZAP700.50157673
91EPHA20.50067454
92RET0.49190286
93RAF10.49060274
94PRKG20.48732348
95PTK2B0.48629251
96GSK3A0.48483130
97PRKACB0.48438981
98PRKD30.45612234
99PTK20.45542505
100STK40.45398917
101KSR10.45228973
102SGK2230.44914057
103SGK4940.44914057
104OXSR10.43789918
105AKT20.43500864
106RPS6KA20.42946005
107IRAK30.42681016
108STK30.40093835
109TGFBR10.40086131
110STK38L0.39050973
111RPS6KC10.37923774
112RPS6KL10.37923774
113MELK0.37729507
114MARK20.37585555
115MAPK100.37327320
116CAMK2G0.37250733
117PDPK10.36561089
118SCYL20.36051191
119STK380.35970584
120RPS6KB10.35816836
121PRKCH0.35353693
122LATS20.34893205
123MST1R0.34856427
124DAPK30.34296945
125MAPK40.32819710
126KSR20.32281258
127PRKCE0.32005854
128CSNK1D0.31695342
129PIK3CG0.31068940
130RPS6KB20.30571402
131RPS6KA60.30400034
132PRKG10.29896235

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.70020204
2Dilated cardiomyopathy_Homo sapiens_hsa054143.64781654
3Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.55399375
42-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.97144050
5Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.96668134
6Cardiac muscle contraction_Homo sapiens_hsa042602.89896256
7Propanoate metabolism_Homo sapiens_hsa006402.24390785
8Fatty acid degradation_Homo sapiens_hsa000712.13935982
9Fatty acid metabolism_Homo sapiens_hsa012121.86736511
10ECM-receptor interaction_Homo sapiens_hsa045121.79148783
11Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.73991043
12Focal adhesion_Homo sapiens_hsa045101.65859482
13Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.63815150
14Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.62853384
15Viral myocarditis_Homo sapiens_hsa054161.60734166
16Carbon metabolism_Homo sapiens_hsa012001.60070054
17Tight junction_Homo sapiens_hsa045301.58291234
18Nitrogen metabolism_Homo sapiens_hsa009101.51495522
19Insulin resistance_Homo sapiens_hsa049311.31369056
20Adherens junction_Homo sapiens_hsa045201.27876177
21Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.26205298
22PPAR signaling pathway_Homo sapiens_hsa033201.22239592
23cGMP-PKG signaling pathway_Homo sapiens_hsa040221.21763732
24Fatty acid elongation_Homo sapiens_hsa000621.18285495
25Fatty acid biosynthesis_Homo sapiens_hsa000611.17585956
26Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.15128529
27Endometrial cancer_Homo sapiens_hsa052131.14542760
28Lysine degradation_Homo sapiens_hsa003101.12949504
29Adipocytokine signaling pathway_Homo sapiens_hsa049201.11123959
30Proteoglycans in cancer_Homo sapiens_hsa052051.09258301
31Amoebiasis_Homo sapiens_hsa051461.06300077
32AMPK signaling pathway_Homo sapiens_hsa041521.01246541
33Thyroid cancer_Homo sapiens_hsa052161.00779395
34Glioma_Homo sapiens_hsa052140.99502709
35Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.98788192
36Other glycan degradation_Homo sapiens_hsa005110.96527040
37Oxytocin signaling pathway_Homo sapiens_hsa049210.94838280
38Pancreatic cancer_Homo sapiens_hsa052120.93528050
39Insulin signaling pathway_Homo sapiens_hsa049100.93399799
40Vascular smooth muscle contraction_Homo sapiens_hsa042700.92272354
41Renal cell carcinoma_Homo sapiens_hsa052110.91650901
42ErbB signaling pathway_Homo sapiens_hsa040120.91640799
43Starch and sucrose metabolism_Homo sapiens_hsa005000.90524346
44Bladder cancer_Homo sapiens_hsa052190.90247121
45Central carbon metabolism in cancer_Homo sapiens_hsa052300.89641330
46Pyruvate metabolism_Homo sapiens_hsa006200.89230989
47Complement and coagulation cascades_Homo sapiens_hsa046100.88854995
48Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.87875276
49Non-small cell lung cancer_Homo sapiens_hsa052230.87814689
50FoxO signaling pathway_Homo sapiens_hsa040680.86080391
51Butanoate metabolism_Homo sapiens_hsa006500.86027691
52Inositol phosphate metabolism_Homo sapiens_hsa005620.85236029
53Leukocyte transendothelial migration_Homo sapiens_hsa046700.83990508
54Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83857614
55Gastric acid secretion_Homo sapiens_hsa049710.83172246
56Estrogen signaling pathway_Homo sapiens_hsa049150.82575038
57Renin secretion_Homo sapiens_hsa049240.82323227
58Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.82199115
59Thyroid hormone signaling pathway_Homo sapiens_hsa049190.81605140
60Small cell lung cancer_Homo sapiens_hsa052220.79955975
61Regulation of actin cytoskeleton_Homo sapiens_hsa048100.79773582
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.79674741
63Glycosaminoglycan degradation_Homo sapiens_hsa005310.79278477
64Protein digestion and absorption_Homo sapiens_hsa049740.79240007
65Glucagon signaling pathway_Homo sapiens_hsa049220.79195713
66Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.77304767
67Type II diabetes mellitus_Homo sapiens_hsa049300.76929387
68Hippo signaling pathway_Homo sapiens_hsa043900.75760790
69Prolactin signaling pathway_Homo sapiens_hsa049170.75724850
70Phototransduction_Homo sapiens_hsa047440.75289743
71Acute myeloid leukemia_Homo sapiens_hsa052210.74585630
72Biosynthesis of amino acids_Homo sapiens_hsa012300.72828195
73Basal cell carcinoma_Homo sapiens_hsa052170.71837842
74Parkinsons disease_Homo sapiens_hsa050120.71659822
75HIF-1 signaling pathway_Homo sapiens_hsa040660.71225239
76Dorso-ventral axis formation_Homo sapiens_hsa043200.70943833
77Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.70763964
78Choline metabolism in cancer_Homo sapiens_hsa052310.70660950
79Prostate cancer_Homo sapiens_hsa052150.69450471
80Axon guidance_Homo sapiens_hsa043600.69094279
81Bile secretion_Homo sapiens_hsa049760.68578294
82Melanoma_Homo sapiens_hsa052180.67624575
83Prion diseases_Homo sapiens_hsa050200.67544565
84Long-term potentiation_Homo sapiens_hsa047200.67385888
85Arginine biosynthesis_Homo sapiens_hsa002200.67132352
86Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64258339
87Alzheimers disease_Homo sapiens_hsa050100.63568042
88Gap junction_Homo sapiens_hsa045400.63343419
89Longevity regulating pathway - mammal_Homo sapiens_hsa042110.63191040
90Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63093330
91Malaria_Homo sapiens_hsa051440.62385004
92Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.61910839
93Histidine metabolism_Homo sapiens_hsa003400.61502747
94TGF-beta signaling pathway_Homo sapiens_hsa043500.60851804
95Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.60548493
96Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.60530025
97Notch signaling pathway_Homo sapiens_hsa043300.60499838
98Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.58993957
99cAMP signaling pathway_Homo sapiens_hsa040240.58448475
100Platelet activation_Homo sapiens_hsa046110.58113906
101mTOR signaling pathway_Homo sapiens_hsa041500.57036756
102Pentose phosphate pathway_Homo sapiens_hsa000300.56914515
103Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.54518424
104MAPK signaling pathway_Homo sapiens_hsa040100.53825547
105Calcium signaling pathway_Homo sapiens_hsa040200.53802449
106AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.52174386
107Arginine and proline metabolism_Homo sapiens_hsa003300.52004520
108Fat digestion and absorption_Homo sapiens_hsa049750.50923482
109PI3K-Akt signaling pathway_Homo sapiens_hsa041510.50712926
110Toxoplasmosis_Homo sapiens_hsa051450.50170383
111Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.49670793
112Long-term depression_Homo sapiens_hsa047300.49634016
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.49558419
114Sphingolipid signaling pathway_Homo sapiens_hsa040710.49213419
115Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.48786552
116Rap1 signaling pathway_Homo sapiens_hsa040150.47925084
117GnRH signaling pathway_Homo sapiens_hsa049120.47892217
118Circadian rhythm_Homo sapiens_hsa047100.47620926
119VEGF signaling pathway_Homo sapiens_hsa043700.47341470
120Salivary secretion_Homo sapiens_hsa049700.46495861
121Pathways in cancer_Homo sapiens_hsa052000.46016954
122Melanogenesis_Homo sapiens_hsa049160.45485943
123MicroRNAs in cancer_Homo sapiens_hsa052060.44816144
124Ovarian steroidogenesis_Homo sapiens_hsa049130.44796521
125beta-Alanine metabolism_Homo sapiens_hsa004100.44132062
126Mineral absorption_Homo sapiens_hsa049780.43864422
127Aldosterone synthesis and secretion_Homo sapiens_hsa049250.43645783
128Circadian entrainment_Homo sapiens_hsa047130.42145665
129Hedgehog signaling pathway_Homo sapiens_hsa043400.40973422
130Cholinergic synapse_Homo sapiens_hsa047250.40518511
131Tryptophan metabolism_Homo sapiens_hsa003800.40493917
132Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.39036041
133Galactose metabolism_Homo sapiens_hsa000520.37825939
134Chronic myeloid leukemia_Homo sapiens_hsa052200.37500634

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