ARCHS4

Functional Annotation Prediction

Predicted biological processes (GO)

Rank	Gene Set	Z-score
1	replication fork processing (GO:0031297)	5.68445915
2	kinetochore organization (GO:0051383)	5.51193220
3	meiotic chromosome segregation (GO:0045132)	5.29568530
4	maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)	5.27384805
5	kinetochore assembly (GO:0051382)	5.25517478
6	mitotic sister chromatid segregation (GO:0000070)	5.19309178
7	sister chromatid segregation (GO:0000819)	4.77132723
8	positive regulation of mitotic metaphase/anaphase transition (GO:0045842)	4.72817349
9	positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)	4.72817349
10	positive regulation of mitotic sister chromatid separation (GO:1901970)	4.72817349
11	DNA strand renaturation (GO:0000733)	4.56120898
12	regulation of centriole replication (GO:0046599)	4.55588530
13	chromosome condensation (GO:0030261)	4.49222686
14	protein localization to kinetochore (GO:0034501)	4.36924424
15	somatic hypermutation of immunoglobulin genes (GO:0016446)	4.31414600
16	somatic diversification of immune receptors via somatic mutation (GO:0002566)	4.31414600
17	telomere maintenance via semi-conservative replication (GO:0032201)	4.27110805
18	proline biosynthetic process (GO:0006561)	4.22730376
19	histone exchange (GO:0043486)	4.22480800
20	mitotic metaphase plate congression (GO:0007080)	4.20576607
21	positive regulation of chromosome segregation (GO:0051984)	4.20140218
22	regulation of sister chromatid cohesion (GO:0007063)	4.15195496
23	DNA topological change (GO:0006265)	4.07782488
24	mitotic chromosome condensation (GO:0007076)	4.04177871
25	protein localization to chromosome, centromeric region (GO:0071459)	4.00937178
26	DNA packaging (GO:0006323)	3.97033551
27	telomere maintenance via recombination (GO:0000722)	3.96604500
28	DNA strand elongation involved in DNA replication (GO:0006271)	3.93249235
29	nuclear pore complex assembly (GO:0051292)	3.93230493
30	nuclear pore organization (GO:0006999)	3.91962898
31	embryonic process involved in female pregnancy (GO:0060136)	3.90738921
32	mitotic recombination (GO:0006312)	3.84803891
33	dosage compensation (GO:0007549)	3.84105866
34	nucleotide-excision repair, DNA gap filling (GO:0006297)	3.83124886
35	metaphase plate congression (GO:0051310)	3.82900769
36	regulation of double-strand break repair via homologous recombination (GO:0010569)	3.78483017
37	DNA strand elongation (GO:0022616)	3.76968498
38	mitotic nuclear envelope disassembly (GO:0007077)	3.74985752
39	regulation of DNA endoreduplication (GO:0032875)	3.71511870
40	transcription from mitochondrial promoter (GO:0006390)	3.70734268
41	regulation of centrosome duplication (GO:0010824)	3.68362813
42	attachment of spindle microtubules to kinetochore (GO:0008608)	3.65846185
43	DNA ligation (GO:0006266)	3.63738965
44	chromosome segregation (GO:0007059)	3.63080728
45	establishment of chromosome localization (GO:0051303)	3.59396183
46	DNA double-strand break processing (GO:0000729)	3.58420823
47	regulation of double-strand break repair (GO:2000779)	3.56814122
48	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla	3.49809910
49	base-excision repair (GO:0006284)	3.48149393
50	telomere maintenance via telomere lengthening (GO:0010833)	3.47514375
51	protein K6-linked ubiquitination (GO:0085020)	3.45853531
52	negative regulation of chromosome segregation (GO:0051985)	3.45072021
53	establishment of integrated proviral latency (GO:0075713)	3.43971755
54	DNA conformation change (GO:0071103)	3.43484212
55	nuclear envelope disassembly (GO:0051081)	3.43298282
56	membrane disassembly (GO:0030397)	3.43298282
57	DNA replication checkpoint (GO:0000076)	3.41937267
58	mitotic G2/M transition checkpoint (GO:0044818)	3.41556374
59	mitotic sister chromatid cohesion (GO:0007064)	3.41229020
60	spindle assembly involved in mitosis (GO:0090307)	3.39578857
61	ATP-dependent chromatin remodeling (GO:0043044)	3.37026237
62	regulation of RNA export from nucleus (GO:0046831)	3.36269924
63	regulation of attachment of spindle microtubules to kinetochore (GO:0051988)	3.35458714
64	regulation of mitotic metaphase/anaphase transition (GO:0030071)	3.32852057
65	mitotic spindle organization (GO:0007052)	3.32788342
66	regulation of spindle organization (GO:0090224)	3.32681003
67	negative regulation of mitosis (GO:0045839)	3.31597940
68	chromatin remodeling at centromere (GO:0031055)	3.31525498
69	DNA replication initiation (GO:0006270)	3.31030867
70	viral mRNA export from host cell nucleus (GO:0046784)	3.29408126
71	regulation of chromosome segregation (GO:0051983)	3.28702860
72	mitotic cell cycle (GO:0000278)	3.27626908
73	regulation of metaphase/anaphase transition of cell cycle (GO:1902099)	3.27598114
74	histone-serine phosphorylation (GO:0035404)	3.27143265
75	spindle checkpoint (GO:0031577)	3.27138605
76	regulation of sister chromatid segregation (GO:0033045)	3.27090822
77	regulation of mitotic sister chromatid separation (GO:0010965)	3.27090822
78	regulation of mitotic sister chromatid segregation (GO:0033047)	3.27090822
79	CENP-A containing nucleosome assembly (GO:0034080)	3.26792590
80	DNA unwinding involved in DNA replication (GO:0006268)	3.26193320
81	chromatin assembly or disassembly (GO:0006333)	3.25695314
82	regulation of centrosome cycle (GO:0046605)	3.25606979
83	maturation of 5.8S rRNA (GO:0000460)	3.25080772
84	microtubule depolymerization (GO:0007019)	3.24641925
85	mitotic cytokinesis (GO:0000281)	3.23728992
86	centriole replication (GO:0007099)	3.22144815
87	DNA damage response, signal transduction resulting in transcription (GO:0042772)	3.20341850
88	poly(A)+ mRNA export from nucleus (GO:0016973)	3.18534364
89	resolution of meiotic recombination intermediates (GO:0000712)	3.18499580
90	nuclear envelope organization (GO:0006998)	3.16597705
91	regulation of spindle checkpoint (GO:0090231)	3.14381920
92	mismatch repair (GO:0006298)	3.13815992
93	DNA replication-dependent nucleosome assembly (GO:0006335)	3.13127374
94	DNA replication-dependent nucleosome organization (GO:0034723)	3.13127374
95	regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)	3.12972397
96	spindle assembly checkpoint (GO:0071173)	3.12103318
97	chromosome organization (GO:0051276)	3.12083672
98	regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)	3.11085296
99	regulation of mitotic spindle checkpoint (GO:1903504)	3.11085296
100	mitochondrial DNA metabolic process (GO:0032042)	3.10628050
101	negative regulation of DNA-dependent DNA replication (GO:2000104)	3.10060613
102	DNA integration (GO:0015074)	3.09325957
103	DNA geometric change (GO:0032392)	3.09149043
104	DNA duplex unwinding (GO:0032508)	3.07906863
105	DNA deamination (GO:0045006)	3.07250041
106	DNA replication-independent nucleosome organization (GO:0034724)	3.07054247
107	DNA replication-independent nucleosome assembly (GO:0006336)	3.07054247
108	non-recombinational repair (GO:0000726)	3.06189806
109	double-strand break repair via nonhomologous end joining (GO:0006303)	3.06189806
110	negative regulation of mRNA splicing, via spliceosome (GO:0048025)	3.06089333
111	DNA synthesis involved in DNA repair (GO:0000731)	3.04943426
112	pore complex assembly (GO:0046931)	3.04924704
113	regulation of mitotic spindle organization (GO:0060236)	3.02555915
114	spindle organization (GO:0007051)	3.01698281
115	mitotic nuclear division (GO:0007067)	3.01675957
116	regulation of histone H3-K9 methylation (GO:0051570)	3.01182175
117	negative regulation of mitotic sister chromatid segregation (GO:0033048)	3.00620563
118	negative regulation of mitotic metaphase/anaphase transition (GO:0045841)	3.00620563
119	negative regulation of sister chromatid segregation (GO:0033046)	3.00620563
120	negative regulation of mitotic sister chromatid separation (GO:2000816)	3.00620563
121	mitotic spindle checkpoint (GO:0071174)	3.00300453
122	mitotic spindle assembly checkpoint (GO:0007094)	2.99310171
123	protein localization to chromosome (GO:0034502)	2.97893042
124	regulation of nuclear cell cycle DNA replication (GO:0033262)	2.96830804
125	histone H4-K12 acetylation (GO:0043983)	2.95830123
126	negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)	2.94769328

Predicted upstream transcription factors (ChEA)

Rank	Gene Set	Z-score
1	* FOXM1_23109430_ChIP-Seq_U2OS_Human	6.58845732
2	E2F4_17652178_ChIP-ChIP_JURKAT_Human	4.57296957
3	* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human	4.24203878
4	MYC_18555785_ChIP-Seq_MESCs_Mouse	3.29778223
5	SMAD1_18555785_ChIP-Seq_MESCs_Mouse	2.62587022
6	E2F1_21310950_ChIP-Seq_MCF-7_Human	2.45412352
7	MYC_19079543_ChIP-ChIP_MESCs_Mouse	2.40896642
8	* KDM5B_21448134_ChIP-Seq_MESCs_Mouse	2.36547347
9	MYC_19030024_ChIP-ChIP_MESCs_Mouse	2.34389477
10	SALL1_21062744_ChIP-ChIP_HESCs_Human	2.28691162
11	MYCN_21190229_ChIP-Seq_SHEP-21N_Human	2.24487638
12	MYBL2_22936984_ChIP-ChIP_MESCs_Mouse	2.20640300
13	KLF2_18264089_ChIP-ChIP_MESCs_Mouse	2.15393840
14	KLF5_18264089_ChIP-ChIP_MESCs_Mouse	2.15393840
15	KLF4_18264089_ChIP-ChIP_MESCs_Mouse	2.15393840
16	EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse	2.11382033
17	TP63_19390658_ChIP-ChIP_HaCaT_Human	2.08148573
18	MYC_18358816_ChIP-ChIP_MESCs_Mouse	2.07802297
19	E2F7_22180533_ChIP-Seq_HELA_Human	10.0757080
20	NELFA_20434984_ChIP-Seq_ESCs_Mouse	1.97025743
21	MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse	1.96966171
22	CHD1_19587682_ChIP-ChIP_MESCs_Mouse	1.89307412
23	AR_21909140_ChIP-Seq_LNCAP_Human	1.88862075
24	NANOG_18555785_ChIP-Seq_MESCs_Mouse	1.81334943
25	MYCN_18555785_ChIP-Seq_MESCs_Mouse	1.80912323
26	EGR1_19374776_ChIP-ChIP_THP-1_Human	1.73925191
27	PADI4_21655091_ChIP-ChIP_MCF-7_Human	1.72811776
28	ZFP281_18358816_ChIP-ChIP_MESCs_Mouse	1.67543498
29	RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse	1.66530506
30	EST1_17652178_ChIP-ChIP_JURKAT_Human	1.64889484
31	NANOG_18700969_ChIP-ChIP_MESCs_Mouse	1.54305423
32	* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human	1.53724989
33	TCF3_18692474_ChIP-Seq_MESCs_Mouse	1.51370152
34	POU5F1_18555785_ChIP-Seq_MESCs_Mouse	1.51314024
35	POU5F1_18358816_ChIP-ChIP_MESCs_Mouse	1.48673349
36	MYC_22102868_ChIP-Seq_BL_Human	1.48328441
37	XRN2_22483619_ChIP-Seq_HELA_Human	1.47903551
38	JARID1A_20064375_ChIP-Seq_MESCs_Mouse	1.47663941
39	E2F1_18555785_ChIP-Seq_MESCs_Mouse	1.47563939
40	TTF2_22483619_ChIP-Seq_HELA_Human	1.47081438
41	NANOG_21062744_ChIP-ChIP_HESCs_Human	1.45846974
42	DACH1_20351289_ChIP-Seq_MDA-MB-231_Human	1.45112714
43	VDR_21846776_ChIP-Seq_THP-1_Human	1.43804433
44	THAP11_20581084_ChIP-Seq_MESCs_Mouse	1.43419402
45	SOX2_18555785_ChIP-Seq_MESCs_Mouse	1.42021871
46	SOX2_18358816_ChIP-ChIP_MESCs_Mouse	1.41461458
47	VDR_23849224_ChIP-Seq_CD4+_Human	1.41224194
48	HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human	1.40600899
49	KDM5A_27292631_Chip-Seq_BREAST_Human	1.39972710
50	ETS1_20019798_ChIP-Seq_JURKAT_Human	1.39238159
51	SALL4_18804426_ChIP-ChIP_MESCs_Mouse	1.34897381
52	DCP1A_22483619_ChIP-Seq_HELA_Human	1.32736154
53	HCFC1_20581084_ChIP-Seq_MESCs_Mouse	1.30315241
54	NACC1_18358816_ChIP-ChIP_MESCs_Mouse	1.29998840
55	KLF4_18358816_ChIP-ChIP_MESCs_Mouse	1.29871004
56	PRDM5_23873026_ChIP-Seq_MEFs_Mouse	1.29359147
57	YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse	1.28427831
58	POU5F1_16518401_ChIP-PET_MESCs_Mouse	1.26440169
59	MYC_18940864_ChIP-ChIP_HL60_Human	1.26145619
60	ELK1_19687146_ChIP-ChIP_HELA_Human	1.26020493
61	GABP_19822575_ChIP-Seq_HepG2_Human	1.25147633
62	SMAD3_22036565_ChIP-Seq_ESCs_Mouse	1.24986608
63	KLF4_18555785_ChIP-Seq_MESCs_Mouse	1.23216601
64	HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse	1.22930153
65	STAT3_1855785_ChIP-Seq_MESCs_Mouse	1.20635739
66	CCND1_20090754_ChIP-ChIP_RETINA_Mouse	1.19869776
67	POU5F1_18700969_ChIP-ChIP_MESCs_Mouse	1.19365751
68	NANOG_18358816_ChIP-ChIP_MESCs_Mouse	1.19149818
69	ZFP42_18358816_ChIP-ChIP_MESCs_Mouse	1.18006648
70	* FOXP3_21729870_ChIP-Seq_TREG_Human	1.16647961
71	CREB1_15753290_ChIP-ChIP_HEK293T_Human	1.16491580
72	YY1_21170310_ChIP-Seq_MESCs_Mouse	1.16478158
73	SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse	1.16343962
74	EWS_26573619_Chip-Seq_HEK293_Human	1.15710567
75	GABP_17652178_ChIP-ChIP_JURKAT_Human	1.13578332
76	PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse	1.12432562
77	NANOG_18347094_ChIP-ChIP_MESCs_Mouse	1.12396195
78	TCF3_18692474_ChIP-Seq_MEFs_Mouse	1.09854650
79	RBPJ_22232070_ChIP-Seq_NCS_Mouse	1.09829833
80	NOTCH1_17114293_ChIP-ChIP_T-ALL_Human	1.09605839
81	ESR1_15608294_ChIP-ChIP_MCF-7_Human	1.09403989
82	ZIC3_20872845_ChIP-ChIP_MESCs_Mouse	1.05853909
83	ZFX_18555785_ChIP-Seq_MESCs_Mouse	1.04702064
84	E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse	1.04153277
85	ASH2L_23239880_ChIP-Seq_MESCs_Mouse	1.03498288
86	HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse	1.03235490
87	ASXL1_24218140_ChIP-Seq_BMDM_Mouse	1.01943173
88	SOX2_16153702_ChIP-ChIP_HESCs_Human	1.00097556
89	FUS_26573619_Chip-Seq_HEK293_Human	0.99993320
90	CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse	0.99460304
91	HOXB4_20404135_ChIP-ChIP_EML_Mouse	0.98850356
92	CNOT3_19339689_ChIP-ChIP_MESCs_Mouse	0.96976407
93	TAL1_20887958_ChIP-Seq_HPC-7_Mouse	0.96973350
94	SOX2_19030024_ChIP-ChIP_MESCs_Mouse	0.96879751
95	SOX2_18692474_ChIP-Seq_MESCs_Mouse	0.96516581
96	NANOG_16153702_ChIP-ChIP_HESCs_Human	0.96332145
97	BCL3_23251550_ChIP-Seq_MUSCLE_Mouse	0.95661863
98	FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse	0.94044792
99	SOX17_20123909_ChIP-Seq_XEN_Mouse	0.93613492
100	FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse	0.93515965
101	KLF4_19030024_ChIP-ChIP_MESCs_Mouse	0.92954059
102	* POU5F1_18692474_ChIP-Seq_MESCs_Mouse	0.90515679
103	CIITA_25753668_ChIP-Seq_RAJI_Human	0.89836607
104	ERG_20887958_ChIP-Seq_HPC-7_Mouse	0.89574912
105	CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat	0.89411774
106	NANOG_18692474_ChIP-Seq_MESCs_Mouse	0.89270519
107	TFEB_21752829_ChIP-Seq_HELA_Human	0.88116952
108	SRF_21415370_ChIP-Seq_HL-1_Mouse	0.88036637
109	SPI1_22096565_ChIP-ChIP_GC-B_Mouse	0.86990749
110	PKCTHETA_26484144_Chip-Seq_BREAST_Human	0.86205684
111	* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human	0.83965650
112	SFPI1_20887958_ChIP-Seq_HPC-7_Mouse	0.83756513
113	POU5F1_16153702_ChIP-ChIP_HESCs_Human	0.83086174
114	DMRT1_21621532_ChIP-ChIP_FETAL_Ovary	0.82509569
115	* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse	0.82257295
116	TCF3_18347094_ChIP-ChIP_MESCs_Mouse	0.80206430
117	FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human	0.77272267
118	* CHD1_26751641_Chip-Seq_LNCaP_Human	0.73740495
119	SMAD4_19686287_ChIP-ChIP_HaCaT_Human	0.70431730
120	ELF1_17652178_ChIP-ChIP_JURKAT_Human	0.70237885
121	PDX1_19855005_ChIP-ChIP_MIN6_Mouse	0.66943567
122	CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human	0.66870379
123	WT1_19549856_ChIP-ChIP_CCG9911_Human	0.64133812
124	NOTCH1_21737748_ChIP-Seq_TLL_Human	0.62573599
125	TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse	0.61233654
126	TRIM28_19339689_ChIP-ChIP_MESCs_Mouse	0.60974244
127	IRF1_19129219_ChIP-ChIP_H3396_Human	0.60719854
128	POU3F2_20337985_ChIP-ChIP_501MEL_Human	0.60126374
129	SOX9_26525672_Chip-Seq_HEART_Mouse	0.59329853

Predicted mouse phenotypes (MGI)

Rank	Gene Set	Z-score
1	MP0008057_abnormal_DNA_replication	5.51692359
2	MP0010094_abnormal_chromosome_stability	4.54725754
3	MP0003111_abnormal_nucleus_morphology	3.94712501
4	MP0003693_abnormal_embryo_hatching	3.87543875
5	MP0003077_abnormal_cell_cycle	3.26893431
6	MP0004957_abnormal_blastocyst_morpholog	3.23716965
7	MP0008058_abnormal_DNA_repair	3.03290947
8	MP0008877_abnormal_DNA_methylation	2.89126953
9	MP0009697_abnormal_copulation	2.54182684
10	MP0008932_abnormal_embryonic_tissue	2.36802655
11	MP0010030_abnormal_orbit_morphology	2.34528034
12	MP0005171_absent_coat_pigmentation	2.32453401
13	MP0009278_abnormal_bone_marrow	2.31502949
14	MP0003786_premature_aging	2.16522058
15	MP0003890_abnormal_embryonic-extraembry	2.02859157
16	MP0010307_abnormal_tumor_latency	1.95807253
17	MP0008007_abnormal_cellular_replicative	1.95486468
18	MP0002009_preneoplasia	1.94522148
19	MP0000350_abnormal_cell_proliferation	1.93391353
20	MP0001730_embryonic_growth_arrest	1.70496158
21	MP0005076_abnormal_cell_differentiation	1.70424093
22	MP0003718_maternal_effect	1.68726792
23	MP0002396_abnormal_hematopoietic_system	1.68119332
24	MP0001672_abnormal_embryogenesis/_devel	1.67771537
25	MP0005380_embryogenesis_phenotype	1.67771537
26	MP0001697_abnormal_embryo_size	1.67560798
27	MP0008995_early_reproductive_senescence	1.65911719
28	MP0000490_abnormal_crypts_of	1.65719256
29	MP0002085_abnormal_embryonic_tissue	1.65333703
30	MP0002084_abnormal_developmental_patter	1.64029487
31	MP0001545_abnormal_hematopoietic_system	1.63444839
32	MP0005397_hematopoietic_system_phenotyp	1.63444839
33	MP0002086_abnormal_extraembryonic_tissu	1.56671856
34	MP0010352_gastrointestinal_tract_polyps	1.56448628
35	MP0005174_abnormal_tail_pigmentation	1.51621049
36	MP0004197_abnormal_fetal_growth/weight/	1.43869499
37	MP0000015_abnormal_ear_pigmentation	1.43120132
38	MP0003941_abnormal_skin_development	1.40385325
39	MP0002877_abnormal_melanocyte_morpholog	1.40143009
40	MP0001293_anophthalmia	1.39696104
41	MP0003984_embryonic_growth_retardation	1.36440387
42	MP0003567_abnormal_fetal_cardiomyocyte	1.33362360
43	MP0009672_abnormal_birth_weight	1.31848787
44	MP0002088_abnormal_embryonic_growth/wei	1.31598425
45	MP0003121_genomic_imprinting	1.31103638
46	MP0003787_abnormal_imprinting	1.31071006
47	MP0002019_abnormal_tumor_incidence	1.29146820
48	MP0000372_irregular_coat_pigmentation	1.26784043
49	MP0002249_abnormal_larynx_morphology	1.26663412
50	MP0004233_abnormal_muscle_weight	1.24509069
51	MP0002653_abnormal_ependyma_morphology	1.21530808
52	MP0000313_abnormal_cell_death	1.21197639
53	MP0002080_prenatal_lethality	1.20702284
54	MP0002210_abnormal_sex_determination	1.19125670
55	MP0003119_abnormal_digestive_system	1.17621840
56	MP0006292_abnormal_olfactory_placode	1.16382326
57	MP0003123_paternal_imprinting	1.08996233
58	MP0001119_abnormal_female_reproductive	1.07887630
59	MP0001145_abnormal_male_reproductive	1.06015914
60	MP0000579_abnormal_nail_morphology	1.04699885
61	MP0000428_abnormal_craniofacial_morphol	1.03721919
62	MP0001929_abnormal_gametogenesis	1.00184613
63	MP0000653_abnormal_sex_gland	0.99068789
64	MP0003755_abnormal_palate_morphology	0.97955632
65	MP0002111_abnormal_tail_morphology	0.96782468
66	MP0000358_abnormal_cell_content/	0.96294119
67	MP0000566_synostosis	0.95443090
68	MP0000537_abnormal_urethra_morphology	0.95064110
69	MP0000432_abnormal_head_morphology	0.94975273
70	MP0005408_hypopigmentation	0.94381656
71	MP0002092_abnormal_eye_morphology	0.93732894
72	MP0006072_abnormal_retinal_apoptosis	0.92593495
73	MP0006035_abnormal_mitochondrial_morpho	0.92553457
74	MP0003937_abnormal_limbs/digits/tail_de	0.91975357
75	MP0002233_abnormal_nose_morphology	0.91665918
76	MP0003950_abnormal_plasma_membrane	0.91532854
77	MP0002234_abnormal_pharynx_morphology	0.90364605
78	MP0003453_abnormal_keratinocyte_physiol	0.89949456
79	MP0004133_heterotaxia	0.89723166
80	MP0002075_abnormal_coat/hair_pigmentati	0.89690078
81	MP0003806_abnormal_nucleotide_metabolis	0.89301220
82	MP0002282_abnormal_trachea_morphology	0.88780106
83	MP0004808_abnormal_hematopoietic_stem	0.88735584
84	MP0003935_abnormal_craniofacial_develop	0.87016386
85	MP0004264_abnormal_extraembryonic_tissu	0.86143840
86	MP0001186_pigmentation_phenotype	0.85606336
87	MP0003136_yellow_coat_color	0.84775524
88	MP0000371_diluted_coat_color	0.84119963
89	MP0000703_abnormal_thymus_morphology	0.84051102
90	MP0003705_abnormal_hypodermis_morpholog	0.83601431
91	MP0000647_abnormal_sebaceous_gland	0.83319502
92	MP0003861_abnormal_nervous_system	0.82599958
93	MP0003699_abnormal_female_reproductive	0.79736241
94	MP0000470_abnormal_stomach_morphology	0.79197395
95	MP0000569_abnormal_digit_pigmentation	0.78177492
96	MP0003763_abnormal_thymus_physiology	0.77830235
97	MP0005075_abnormal_melanosome_morpholog	0.76648340
98	MP0003385_abnormal_body_wall	0.76338192
99	MP0003315_abnormal_perineum_morphology	0.75762543
100	MP0002114_abnormal_axial_skeleton	0.75343044
101	MP0002398_abnormal_bone_marrow	0.74969304
102	MP0002932_abnormal_joint_morphology	0.74403322
103	MP0001346_abnormal_lacrimal_gland	0.73799754
104	MP0002116_abnormal_craniofacial_bone	0.73492270
105	MP0002938_white_spotting	0.72963323
106	MP0003943_abnormal_hepatobiliary_system	0.72848384
107	MP0009053_abnormal_anal_canal	0.71928482
108	MP0004147_increased_porphyrin_level	0.71614811
109	MP0000689_abnormal_spleen_morphology	0.70697727
110	MP0001286_abnormal_eye_development	0.70397573
111	MP0002095_abnormal_skin_pigmentation	0.70201224
112	MP0005391_vision/eye_phenotype	0.69512899
113	MP0005395_other_phenotype	0.69362655
114	MP0003698_abnormal_male_reproductive	0.69249194
115	MP0000427_abnormal_hair_cycle	0.68814225
116	MP0005384_cellular_phenotype	0.67616555
117	MP0009703_decreased_birth_body	0.67420318
118	MP0000462_abnormal_digestive_system	0.66968484
119	MP0009333_abnormal_splenocyte_physiolog	0.66112342
120	MP0002163_abnormal_gland_morphology	0.65498607
121	MP0004185_abnormal_adipocyte_glucose	0.65176394
122	MP0002722_abnormal_immune_system	0.64830218
123	MP0002697_abnormal_eye_size	0.64754959
124	MP0002160_abnormal_reproductive_system	0.64739347
125	MP0003221_abnormal_cardiomyocyte_apopto	0.63568309
126	MP0002006_tumorigenesis	0.63401417
127	MP0002161_abnormal_fertility/fecundity	0.62320498
128	MP0001915_intracranial_hemorrhage	0.61969975
129	MP0001299_abnormal_eye_distance/	0.61444039
130	MP0000762_abnormal_tongue_morphology	0.61293740
131	MP0003566_abnormal_cell_adhesion	0.61174147
132	MP0005621_abnormal_cell_physiology	0.61152830
133	MP0000049_abnormal_middle_ear	0.60733546
134	MP0001661_extended_life_span	0.59684101
135	MP0002102_abnormal_ear_morphology	0.59384821
136	MP0002177_abnormal_outer_ear	0.58645386

Predicted human phenotypes

Rank	Gene Set	Z-score
1	Chromsome breakage (HP:0040012)	5.14201694
2	Chromosomal breakage induced by crosslinking agents (HP:0003221)	5.12127965
3	Facial hemangioma (HP:0000329)	4.11304275
4	Increased nuchal translucency (HP:0010880)	4.05532003
5	Rib fusion (HP:0000902)	3.96175729
6	Volvulus (HP:0002580)	3.93541798
7	Patellar aplasia (HP:0006443)	3.69080190
8	Abnormal lung lobation (HP:0002101)	3.68834425
9	Absent radius (HP:0003974)	3.60668209
10	Cortical dysplasia (HP:0002539)	3.58421045
11	Abnormality of the labia minora (HP:0012880)	3.55893338
12	Abnormality of the ileum (HP:0001549)	3.54564244
13	Hypochromic microcytic anemia (HP:0004840)	3.48173613
14	Aplasia/Hypoplasia of the patella (HP:0006498)	3.41043712
15	Aplasia involving forearm bones (HP:0009822)	3.36740098
16	Absent forearm bone (HP:0003953)	3.36740098
17	Abnormality of chromosome stability (HP:0003220)	3.26315073
18	Aplasia/Hypoplasia of the uvula (HP:0010293)	3.23720848
19	Intestinal fistula (HP:0100819)	3.20382008
20	Rectal fistula (HP:0100590)	3.20062736
21	Rectovaginal fistula (HP:0000143)	3.20062736
22	Ectopic kidney (HP:0000086)	3.08064818
23	Meckel diverticulum (HP:0002245)	3.07628375
24	Poikiloderma (HP:0001029)	3.02703519
25	Absent thumb (HP:0009777)	3.01891568
26	Abnormality of the preputium (HP:0100587)	2.96848370
27	Aplasia/Hypoplasia involving the carpal bones (HP:0006502)	2.96266164
28	Impulsivity (HP:0100710)	2.87884587
29	Birth length less than 3rd percentile (HP:0003561)	2.85186859
30	Aplasia/Hypoplasia of the sacrum (HP:0008517)	2.79394362
31	Concave nail (HP:0001598)	2.76240313
32	Aplasia/hypoplasia of the humerus (HP:0006507)	2.66817615
33	Short thumb (HP:0009778)	2.64473288
34	Short humerus (HP:0005792)	2.63191726
35	Nephroblastoma (Wilms tumor) (HP:0002667)	2.61257315
36	Duplicated collecting system (HP:0000081)	2.60427458
37	Selective tooth agenesis (HP:0001592)	2.60369589
38	Intestinal atresia (HP:0011100)	2.60102227
39	Myelodysplasia (HP:0002863)	2.59588043
40	Squamous cell carcinoma (HP:0002860)	2.57932131
41	Basal cell carcinoma (HP:0002671)	2.50345640
42	Breast hypoplasia (HP:0003187)	2.50038439
43	Premature graying of hair (HP:0002216)	2.49681262
44	Small intestinal stenosis (HP:0012848)	2.49107049
45	Duodenal stenosis (HP:0100867)	2.49107049
46	Neoplasm of the oral cavity (HP:0100649)	2.47989638
47	Rhabdomyosarcoma (HP:0002859)	2.47728701
48	Vaginal fistula (HP:0004320)	2.46961474
49	Medulloblastoma (HP:0002885)	2.45500328
50	Capillary hemangiomas (HP:0005306)	2.45139962
51	Embryonal renal neoplasm (HP:0011794)	2.42195420
52	Pustule (HP:0200039)	2.41129900
53	Abnormality of male internal genitalia (HP:0000022)	2.35989099
54	Abnormality of the renal collecting system (HP:0004742)	2.34110465
55	Overlapping toe (HP:0001845)	2.33611560
56	Embryonal neoplasm (HP:0002898)	2.33109486
57	Neoplasm of the colon (HP:0100273)	2.31212750
58	Colon cancer (HP:0003003)	2.28250510
59	Ulnar bowing (HP:0003031)	2.27085920
60	Prostate neoplasm (HP:0100787)	2.26306611
61	Increased number of teeth (HP:0011069)	2.24627002
62	Acute lymphatic leukemia (HP:0006721)	2.24204729
63	Abnormal number of incisors (HP:0011064)	2.23693280
64	Clubbing of toes (HP:0100760)	2.22115631
65	Aplasia/Hypoplasia of the sternum (HP:0006714)	2.19532998
66	Annular pancreas (HP:0001734)	2.18926287
67	Arteriovenous malformation (HP:0100026)	2.17946826
68	Abnormality of the fingertips (HP:0001211)	2.17629751
69	Lip pit (HP:0100267)	2.17145591
70	Choanal atresia (HP:0000453)	2.13195280
71	Shawl scrotum (HP:0000049)	2.11026553
72	Missing ribs (HP:0000921)	2.10809435
73	Astrocytoma (HP:0009592)	2.09058108
74	Abnormality of the astrocytes (HP:0100707)	2.09058108
75	Abnormality of the carotid arteries (HP:0005344)	2.08051981
76	Increased IgM level (HP:0003496)	2.05012844
77	Proximal placement of thumb (HP:0009623)	2.04946914
78	Abnormality of the duodenum (HP:0002246)	2.04644869
79	Supernumerary spleens (HP:0009799)	2.02924529
80	Ependymoma (HP:0002888)	2.01902857
81	Sloping forehead (HP:0000340)	2.01490028
82	Tongue fasciculations (HP:0001308)	1.99671230
83	Deviation of the thumb (HP:0009603)	1.98390036
84	Orthostatic hypotension (HP:0001278)	1.97693938
85	Cafe-au-lait spot (HP:0000957)	1.97384236
86	11 pairs of ribs (HP:0000878)	1.96530748
87	Hypochromic anemia (HP:0001931)	1.96460088
88	Broad alveolar ridges (HP:0000187)	1.96442644
89	Male infertility (HP:0003251)	1.96003101
90	Abdominal situs inversus (HP:0003363)	1.90563713
91	Abnormality of abdominal situs (HP:0011620)	1.90563713
92	Abnormality of cochlea (HP:0000375)	1.89106908
93	Glioma (HP:0009733)	1.88107773
94	Gastrointestinal atresia (HP:0002589)	1.87226260
95	Prominent nose (HP:0000448)	1.84091796
96	Duplication of thumb phalanx (HP:0009942)	1.83728214
97	Bone marrow hypocellularity (HP:0005528)	1.83493942
98	Sandal gap (HP:0001852)	1.82903847
99	Abnormal auditory evoked potentials (HP:0006958)	1.82369583
100	Abnormality of chromosome segregation (HP:0002916)	1.82254111
101	Broad thumb (HP:0011304)	1.81558748
102	Neoplasm of striated muscle (HP:0009728)	1.80253449
103	Agnosia (HP:0010524)	1.79974573
104	Small hand (HP:0200055)	1.79769754
105	High pitched voice (HP:0001620)	1.78124873
106	Reticulocytopenia (HP:0001896)	1.77779542
107	Hypotelorism (HP:0000601)	1.77716766
108	Abnormality of DNA repair (HP:0003254)	1.77227290
109	High anterior hairline (HP:0009890)	1.75567678
110	Tracheoesophageal fistula (HP:0002575)	1.73530545
111	Pancreatic islet-cell hyperplasia (HP:0004510)	1.71881301
112	Deep philtrum (HP:0002002)	1.70271660
113	Hypoplasia of the radius (HP:0002984)	1.69440101
114	Abnormality of the aortic arch (HP:0012303)	1.68875730
115	Degeneration of anterior horn cells (HP:0002398)	1.68392764
116	Abnormality of the anterior horn cell (HP:0006802)	1.68392764
117	Triphalangeal thumb (HP:0001199)	1.67336375
118	Hemivertebrae (HP:0002937)	1.67254636
119	Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)	1.67203451
120	Short 4th metacarpal (HP:0010044)	1.67203451
121	Congenital hip dislocation (HP:0001374)	1.67100728
122	Long clavicles (HP:0000890)	1.67029132
123	Horseshoe kidney (HP:0000085)	1.66763208
124	Acute myeloid leukemia (HP:0004808)	1.64171246
125	Ovarian neoplasm (HP:0100615)	1.63472994
126	Atresia of the external auditory canal (HP:0000413)	1.61937390
127	Hypopigmentation of the fundus (HP:0007894)	1.61355078
128	Multiple enchondromatosis (HP:0005701)	1.60355943
129	Hypoplasia of the pons (HP:0012110)	1.59424660
130	Abnormality of the pons (HP:0007361)	1.59400157
131	Astigmatism (HP:0000483)	1.54034836
132	Aplasia/Hypoplasia of the earlobes (HP:0009906)	1.53826463
133	Microvesicular hepatic steatosis (HP:0001414)	1.53364853
134	Abnormality of glycolysis (HP:0004366)	1.52424616
135	Hypoplastic pelvis (HP:0008839)	1.51479326
136	Progressive external ophthalmoplegia (HP:0000590)	1.50402212
137	Cerebellar dysplasia (HP:0007033)	1.49841457
138	Short middle phalanx of the 5th finger (HP:0004220)	1.49562205
139	Combined immunodeficiency (HP:0005387)	1.49291669
140	Abnormality of the septum pellucidum (HP:0007375)	1.49211923
141	Abnormal umbilical cord blood vessels (HP:0011403)	1.49208492
142	Single umbilical artery (HP:0001195)	1.49208492
143	Abnormality of the fetal cardiovascular system (HP:0010948)	1.49208492
144	Dandy-Walker malformation (HP:0001305)	1.49027629
145	Facial cleft (HP:0002006)	1.47543421
146	Partial agenesis of the corpus callosum (HP:0001338)	1.47469675
147	Obsessive-compulsive behavior (HP:0000722)	1.46815226

Predicted kinase interactions (KEA)

Rank	Gene Set	Z-score
1	CDC7	4.08195835
2	MAP3K6	3.33561358
3	ICK	3.33223821
4	CDK12	3.27843888
5	PBK	2.78536207
6	NEK2	2.77125659
7	DDR2	2.55592628
8	CHEK2	2.35681784
9	TTK	2.31476874
10	CDK7	2.30756150
11	TSSK6	2.28180316
12	WEE1	2.25592506
13	PLK1	2.24878943
14	BUB1	1.98272078
15	MAPK15	1.94198599
16	SRPK1	1.92620910
17	LATS1	1.88237271
18	YES1	1.85451763
19	MATK	1.81488286
20	PLK4	1.78460717
21	FGR	1.77771132
22	ATR	1.76446628
23	BRSK2	1.75569322
24	MAP3K11	1.70319147
25	AURKB	1.67887797
26	PNCK	1.66813618
27	TRPM7	1.63002574
28	EIF2AK3	1.59692618
29	PIM1	1.55354568
30	STK38L	1.54482490
31	CDK6	1.49706685
32	STK3	1.45396200
33	LATS2	1.44895252
34	STK4	1.44820490
35	TAF1	1.41178814
36	CHEK1	1.39012446
37	AKT3	1.38517983
38	STK10	1.36232833
39	MKNK2	1.32370859
40	PRKD2	1.26111286
41	ZAK	1.24507680
42	PINK1	1.24414826
43	TYRO3	1.24330205
44	ATM	1.22828419
45	UHMK1	1.22555723
46	MKNK1	1.22417350
47	TLK1	1.20839679
48	EIF2AK1	1.20814416
49	RPS6KB2	1.20703944
50	CSK	1.17696752
51	PLK3	1.17686009
52	CDK4	1.16538712
53	DAPK1	1.16469720
54	VRK2	1.13318832
55	AURKA	1.13038356
56	BMX	1.09322762
57	MELK	1.08516308
58	SCYL2	1.08502086
59	CDK8	1.07423121
60	NUAK1	1.06195034
61	ACVR1B	1.06031515
62	VRK1	1.05790244
63	BRD4	1.04896251
64	CDK2	1.03285208
65	BRSK1	1.02191036
66	MAP3K8	0.99665807
67	MST4	0.98044753
68	NEK1	0.94894881
69	DYRK3	0.92458785
70	MST1R	0.88179450
71	BMPR1B	0.87385513
72	DYRK1B	0.86559416
73	TRIM28	0.85121874
74	CDK1	0.84352197
75	PIM2	0.83683555
76	EPHA2	0.78031929
77	PDGFRA	0.77272312
78	RPS6KC1	0.77045219
79	RPS6KL1	0.77045219
80	MAPK11	0.73763807
81	EEF2K	0.68899779
82	PRPF4B	0.68127661
83	MTOR	0.66681003
84	MET	0.66365240
85	RPS6KA6	0.64963666
86	ERBB4	0.63854062
87	CSNK2A1	0.61673015
88	TAOK2	0.59655508
89	MAPK14	0.59543648
90	PLK2	0.58140454
91	MAP3K10	0.56682557
92	CDC42BPA	0.53793724
93	CDK9	0.53728637
94	ALK	0.52596903
95	CCNB1	0.51831145
96	CLK1	0.50818974
97	RPS6KA4	0.47745296
98	SMG1	0.46831230
99	CAMK1G	0.46693050
100	AKT1	0.45496196
101	EIF2AK2	0.44663788
102	PDK2	0.44376442
103	CSNK2A2	0.44148723
104	NME1	0.43255067
105	WNK3	0.42921244
106	CHUK	0.42563791
107	MAPK1	0.42299911
108	RPS6KB1	0.41420819
109	PASK	0.41357960
110	PRKAA1	0.40886867
111	RPS6KA1	0.40066767
112	BCR	0.39711161
113	MARK3	0.39615546
114	STK16	0.38172110
115	CDK3	0.37915281
116	CSNK1E	0.37104659
117	ERBB3	0.36595276
118	PRKDC	0.36303746
119	RAF1	0.35939876
120	TGFBR1	0.35917981
121	GSK3B	0.35031131
122	FGFR1	0.34413714
123	CAMK1D	0.34245233
124	LYN	0.34173767
125	RPS6KA5	0.33820451
126	PAK4	0.33479349
127	MAPK10	0.29283278
128	BRAF	0.29155889
129	PAK1	0.28293283
130	CDK18	0.27494244
131	WNK4	0.27305117
132	CSNK1D	0.26876246
133	KSR1	0.26326455
134	MAPK3	0.26274323
135	STK39	0.26039280
136	TNIK	0.25735311
137	AKT2	0.24749654
138	CDK15	0.24728347
139	PRKCI	0.24393875
140	CDK11A	0.23068269
141	NME2	0.22725358
142	FLT3	0.22355482

Predicted pathways (KEGG)

Rank	Gene Set	Z-score
1	Mismatch repair_Homo sapiens_hsa03430	4.78369245
2	DNA replication_Homo sapiens_hsa03030	4.49292079
3	Base excision repair_Homo sapiens_hsa03410	3.84774519
4	Homologous recombination_Homo sapiens_hsa03440	3.43244068
5	Fanconi anemia pathway_Homo sapiens_hsa03460	3.30202926
6	Cell cycle_Homo sapiens_hsa04110	3.12154701
7	Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008	2.94433224
8	Nucleotide excision repair_Homo sapiens_hsa03420	2.80080310
9	RNA transport_Homo sapiens_hsa03013	2.70859051
10	Spliceosome_Homo sapiens_hsa03040	2.64488154
11	mRNA surveillance pathway_Homo sapiens_hsa03015	2.14423238
12	p53 signaling pathway_Homo sapiens_hsa04115	2.09054255
13	Non-homologous end-joining_Homo sapiens_hsa03450	2.08536921
14	Basal transcription factors_Homo sapiens_hsa03022	1.97251177
15	One carbon pool by folate_Homo sapiens_hsa00670	1.92985658
16	RNA polymerase_Homo sapiens_hsa03020	1.78025302
17	RNA degradation_Homo sapiens_hsa03018	1.77436675
18	Fatty acid biosynthesis_Homo sapiens_hsa00061	1.57238194
19	Systemic lupus erythematosus_Homo sapiens_hsa05322	1.56419924
20	Protein export_Homo sapiens_hsa03060	1.35402165
21	Cysteine and methionine metabolism_Homo sapiens_hsa00270	1.32418664
22	Pyrimidine metabolism_Homo sapiens_hsa00240	1.32291610
23	MicroRNAs in cancer_Homo sapiens_hsa05206	1.29521756
24	Transcriptional misregulation in cancer_Homo sapiens_hsa05202	1.28496530
25	Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970	1.26238775
26	Oocyte meiosis_Homo sapiens_hsa04114	1.25491051
27	Ubiquitin mediated proteolysis_Homo sapiens_hsa04120	1.21362719
28	Notch signaling pathway_Homo sapiens_hsa04330	1.20355513
29	Terpenoid backbone biosynthesis_Homo sapiens_hsa00900	1.16876629
30	Viral carcinogenesis_Homo sapiens_hsa05203	1.16572119
31	Hippo signaling pathway_Homo sapiens_hsa04390	1.14701211
32	Adherens junction_Homo sapiens_hsa04520	1.13172466
33	Herpes simplex infection_Homo sapiens_hsa05168	1.11517802
34	Citrate cycle (TCA cycle)_Homo sapiens_hsa00020	1.10916501
35	TGF-beta signaling pathway_Homo sapiens_hsa04350	1.07085414
36	Steroid biosynthesis_Homo sapiens_hsa00100	1.06440539
37	Pyruvate metabolism_Homo sapiens_hsa00620	1.06144858
38	Ribosome_Homo sapiens_hsa03010	1.01855865
39	Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130	0.97481530
40	Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914	0.95189957
41	Epstein-Barr virus infection_Homo sapiens_hsa05169	0.94060905
42	Hedgehog signaling pathway_Homo sapiens_hsa04340	0.93701718
43	Basal cell carcinoma_Homo sapiens_hsa05217	0.93472568
44	mTOR signaling pathway_Homo sapiens_hsa04150	0.92229303
45	Primary immunodeficiency_Homo sapiens_hsa05340	0.90652073
46	Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550	0.89154750
47	Colorectal cancer_Homo sapiens_hsa05210	0.88040190
48	HTLV-I infection_Homo sapiens_hsa05166	0.86126648
49	Small cell lung cancer_Homo sapiens_hsa05222	0.85875389
50	Lysine degradation_Homo sapiens_hsa00310	0.80265069
51	Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630	0.78814778
52	Propanoate metabolism_Homo sapiens_hsa00640	0.77728215
53	Thyroid cancer_Homo sapiens_hsa05216	0.76922388
54	Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770	0.74811317
55	Bladder cancer_Homo sapiens_hsa05219	0.73901355
56	Wnt signaling pathway_Homo sapiens_hsa04310	0.73459883
57	Chronic myeloid leukemia_Homo sapiens_hsa05220	0.73071513
58	Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520	0.71120135
59	Carbon metabolism_Homo sapiens_hsa01200	0.69175745
60	Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141	0.67972072
61	Shigellosis_Homo sapiens_hsa05131	0.67821090
62	2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210	0.67771430
63	Circadian rhythm_Homo sapiens_hsa04710	0.65374551
64	Hepatitis B_Homo sapiens_hsa05161	0.63836178
65	Alcoholism_Homo sapiens_hsa05034	0.60773654
66	Proteasome_Homo sapiens_hsa03050	0.60688434
67	Measles_Homo sapiens_hsa05162	0.60361715
68	Folate biosynthesis_Homo sapiens_hsa00790	0.60196224
69	Pancreatic cancer_Homo sapiens_hsa05212	0.60156344
70	Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623	0.59776536
71	Viral myocarditis_Homo sapiens_hsa05416	0.58989749
72	Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072	0.58571817
73	Huntingtons disease_Homo sapiens_hsa05016	0.57052098
74	N-Glycan biosynthesis_Homo sapiens_hsa00510	0.56900398
75	Purine metabolism_Homo sapiens_hsa00230	0.56288984
76	Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533	0.55217247
77	Prostate cancer_Homo sapiens_hsa05215	0.54414669
78	Legionellosis_Homo sapiens_hsa05134	0.54179604
79	Apoptosis_Homo sapiens_hsa04210	0.53260298
80	Fc epsilon RI signaling pathway_Homo sapiens_hsa04664	0.53249930
81	Regulation of actin cytoskeleton_Homo sapiens_hsa04810	0.52876510
82	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563	0.47686673
83	Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010	0.47054767
84	Glycine, serine and threonine metabolism_Homo sapiens_hsa00260	0.47023984
85	Melanoma_Homo sapiens_hsa05218	0.46962063
86	Endometrial cancer_Homo sapiens_hsa05213	0.46464054
87	Pathways in cancer_Homo sapiens_hsa05200	0.45984689
88	NF-kappa B signaling pathway_Homo sapiens_hsa04064	0.45772306
89	Longevity regulating pathway - mammal_Homo sapiens_hsa04211	0.45218860
90	Intestinal immune network for IgA production_Homo sapiens_hsa04672	0.45077571
91	Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250	0.44652187
92	FoxO signaling pathway_Homo sapiens_hsa04068	0.42503856
93	Central carbon metabolism in cancer_Homo sapiens_hsa05230	0.41616764
94	Pentose phosphate pathway_Homo sapiens_hsa00030	0.40541407
95	Acute myeloid leukemia_Homo sapiens_hsa05221	0.39673906
96	Hematopoietic cell lineage_Homo sapiens_hsa04640	0.38204300
97	Antigen processing and presentation_Homo sapiens_hsa04612	0.37584882
98	Non-small cell lung cancer_Homo sapiens_hsa05223	0.36906877
99	Bacterial invasion of epithelial cells_Homo sapiens_hsa05100	0.35667726
100	Parkinsons disease_Homo sapiens_hsa05012	0.35273473
101	Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860	0.33065832
102	Tight junction_Homo sapiens_hsa04530	0.32970254
103	Glutathione metabolism_Homo sapiens_hsa00480	0.32583484
104	VEGF signaling pathway_Homo sapiens_hsa04370	0.30679649
105	Dorso-ventral axis formation_Homo sapiens_hsa04320	0.30612009
106	Vitamin B6 metabolism_Homo sapiens_hsa00750	0.30522580
107	Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666	0.30222963
108	PI3K-Akt signaling pathway_Homo sapiens_hsa04151	0.27851980
109	Influenza A_Homo sapiens_hsa05164	0.27776618
110	Choline metabolism in cancer_Homo sapiens_hsa05231	0.27716187
111	Proteoglycans in cancer_Homo sapiens_hsa05205	0.27237090
112	B cell receptor signaling pathway_Homo sapiens_hsa04662	0.27228007
113	Metabolic pathways_Homo sapiens_hsa01100	0.26814759
114	Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650	0.26809267
115	Arginine and proline metabolism_Homo sapiens_hsa00330	0.25858764
116	Pathogenic Escherichia coli infection_Homo sapiens_hsa05130	0.25223928
117	RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622	0.23880702
118	Graft-versus-host disease_Homo sapiens_hsa05332	0.23587607
119	NOD-like receptor signaling pathway_Homo sapiens_hsa04621	0.23009676
120	Autoimmune thyroid disease_Homo sapiens_hsa05320	0.22535484
121	Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040	0.22519234
122	Allograft rejection_Homo sapiens_hsa05330	0.22406195
123	Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280	0.22118982
124	Fatty acid elongation_Homo sapiens_hsa00062	0.21826640
125	Jak-STAT signaling pathway_Homo sapiens_hsa04630	0.21717540
126	Biosynthesis of amino acids_Homo sapiens_hsa01230	0.21659347
127	Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400	0.21315274
128	ErbB signaling pathway_Homo sapiens_hsa04012	0.21191900
129	Selenocompound metabolism_Homo sapiens_hsa00450	0.19676255
130	Thyroid hormone signaling pathway_Homo sapiens_hsa04919	0.19658735
131	Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512	0.18033120
132	Fatty acid metabolism_Homo sapiens_hsa01212	0.17543081
133	Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534	0.17300249
134	Oxidative phosphorylation_Homo sapiens_hsa00190	0.16837636
135	Glioma_Homo sapiens_hsa05214	0.13595359
136	Longevity regulating pathway - multiple species_Homo sapiens_hsa04213	0.11101174
137	Cyanoamino acid metabolism_Homo sapiens_hsa00460	0.07013843

KIF14

Functional Annotation Prediction

Predicted biological processes (GO)

Predicted upstream transcription factors (ChEA)

Predicted mouse phenotypes (MGI)

Predicted human phenotypes

Predicted kinase interactions (KEA)

Predicted pathways (KEGG)

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