KIF17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1acrosome reaction (GO:0007340)9.92086893
2fusion of sperm to egg plasma membrane (GO:0007342)9.90409831
3multicellular organism reproduction (GO:0032504)8.95596262
4cell wall macromolecule catabolic process (GO:0016998)8.94746310
5cell wall macromolecule metabolic process (GO:0044036)8.94746310
6sperm-egg recognition (GO:0035036)8.90315861
7axonemal dynein complex assembly (GO:0070286)8.36456140
8acrosome assembly (GO:0001675)8.36126626
9binding of sperm to zona pellucida (GO:0007339)8.17000628
10epithelial cilium movement (GO:0003351)8.14195036
11cell-cell recognition (GO:0009988)7.96753976
12regulation of cilium movement (GO:0003352)7.87485834
13spermatid development (GO:0007286)7.80270564
14plasma membrane fusion (GO:0045026)7.78874373
15piRNA metabolic process (GO:0034587)7.74049573
16motile cilium assembly (GO:0044458)7.73353861
17cilium or flagellum-dependent cell motility (GO:0001539)7.40962652
18reproduction (GO:0000003)7.40570845
19cilium movement (GO:0003341)6.89137712
20male meiosis (GO:0007140)6.75329142
21epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.36957387
22single fertilization (GO:0007338)6.28365229
23synaptonemal complex organization (GO:0070193)6.09502013
24synaptonemal complex assembly (GO:0007130)5.94302268
25negative regulation of inclusion body assembly (GO:0090084)5.87098802
26sperm capacitation (GO:0048240)5.69279044
27microtubule severing (GO:0051013)5.68153813
28spermatogenesis (GO:0007283)5.64565455
29male gamete generation (GO:0048232)5.62739761
30calcium ion-dependent exocytosis (GO:0017156)5.53027335
31fertilization (GO:0009566)5.47221459
32gamete generation (GO:0007276)5.32717899
33microtubule depolymerization (GO:0007019)5.32516395
34organic cation transport (GO:0015695)4.88950989
35synaptic vesicle exocytosis (GO:0016079)4.86232206
36DNA methylation involved in gamete generation (GO:0043046)4.77890783
37regulation of inclusion body assembly (GO:0090083)4.73354889
38male meiosis I (GO:0007141)4.66839859
39regulation of microtubule-based movement (GO:0060632)4.60987176
40germ cell development (GO:0007281)4.57767976
41cellular process involved in reproduction in multicellular organism (GO:0022412)4.56970950
42synaptic vesicle maturation (GO:0016188)4.53813883
43synaptic vesicle docking involved in exocytosis (GO:0016081)4.51976236
44ventricular system development (GO:0021591)4.48348723
45protein polyglutamylation (GO:0018095)4.37276060
46regulation of synaptic vesicle exocytosis (GO:2000300)4.22667896
47cell recognition (GO:0008037)4.22256921
48multicellular organismal reproductive process (GO:0048609)4.20095853
49glutamate secretion (GO:0014047)4.04746772
50chromosome condensation (GO:0030261)3.97502017
51meiotic nuclear division (GO:0007126)3.96475878
52left/right pattern formation (GO:0060972)3.89818011
53DNA packaging (GO:0006323)3.86125825
54chromosome organization involved in meiosis (GO:0070192)3.85406928
55meiosis I (GO:0007127)3.83599236
56seminiferous tubule development (GO:0072520)3.81860121
57meiotic cell cycle (GO:0051321)3.77451374
58regulation of synaptic vesicle transport (GO:1902803)3.74888530
59dendritic spine morphogenesis (GO:0060997)3.66329256
60regulation of synapse structural plasticity (GO:0051823)3.64660877
61monoubiquitinated protein deubiquitination (GO:0035520)3.63668039
62postsynaptic membrane organization (GO:0001941)3.58571094
63vocalization behavior (GO:0071625)3.57882552
64protein localization to cilium (GO:0061512)3.55550554
65dendritic spine organization (GO:0097061)3.50362623
66rRNA methylation (GO:0031167)3.41151050
67glycerol ether metabolic process (GO:0006662)3.40436138
68regulation of acrosome reaction (GO:0060046)3.35407252
69spermatid nucleus differentiation (GO:0007289)3.31470915
70melanin biosynthetic process (GO:0042438)3.30594663
71positive regulation of membrane potential (GO:0045838)3.26065220
72RNA destabilization (GO:0050779)3.24104580
73neurofilament cytoskeleton organization (GO:0060052)3.22783146
74multicellular organismal development (GO:0007275)3.21707604
75regulation of neuronal synaptic plasticity (GO:0048168)3.20095696
76neuronal ion channel clustering (GO:0045161)3.18570573
77regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.17693249
78rRNA modification (GO:0000154)3.17381753
79positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.17299009
80regulation of meiosis I (GO:0060631)3.16952117
81regulation of spindle checkpoint (GO:0090231)3.14942373
82ether metabolic process (GO:0018904)3.14074023
83regulation of cilium assembly (GO:1902017)3.10496667
84G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.09639844
85negative regulation of organelle assembly (GO:1902116)3.07080997
86positive regulation of dendritic spine development (GO:0060999)3.06326227
87neurotransmitter secretion (GO:0007269)3.05727826
88histone arginine methylation (GO:0034969)3.05639593
89neurotransmitter-gated ion channel clustering (GO:0072578)3.04509566
90microtubule polymerization or depolymerization (GO:0031109)3.04031979
91regulation of protein kinase A signaling (GO:0010738)3.01398545
92response to dietary excess (GO:0002021)3.00486459
93synaptic transmission, glutamatergic (GO:0035249)2.99281545
94membrane depolarization during action potential (GO:0086010)2.98575778
95synaptic vesicle endocytosis (GO:0048488)2.97385911
96cilium organization (GO:0044782)2.97227594
97regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.96609898
98response to pheromone (GO:0019236)2.95527805
99peptidyl-arginine omega-N-methylation (GO:0035247)2.95042593
100regulation of long-term neuronal synaptic plasticity (GO:0048169)2.95037868
101cilium assembly (GO:0042384)2.92271879
102mitotic sister chromatid cohesion (GO:0007064)2.91563542
103centriole replication (GO:0007099)2.90352667
104exploration behavior (GO:0035640)2.89914327
105polyol catabolic process (GO:0046174)2.88553129
106calcium ion import (GO:0070509)2.88046901
107short-term memory (GO:0007614)2.87390440
108meiotic cell cycle process (GO:1903046)2.87259407
109single strand break repair (GO:0000012)2.85316037
110ionotropic glutamate receptor signaling pathway (GO:0035235)2.83821552
111regulation of excitatory postsynaptic membrane potential (GO:0060079)2.81084333
112glutamate receptor signaling pathway (GO:0007215)2.77014039
113protein K11-linked deubiquitination (GO:0035871)2.76915111
114sexual reproduction (GO:0019953)2.76216145
115melanin metabolic process (GO:0006582)2.76084843
116gene silencing by RNA (GO:0031047)2.75003512
117* microtubule-based movement (GO:0007018)2.74783805
118intraciliary transport (GO:0042073)2.74600345
119secondary metabolite biosynthetic process (GO:0044550)2.73476306
120neuron-neuron synaptic transmission (GO:0007270)2.69846249
121cilium morphogenesis (GO:0060271)2.67099231
122mitochondrion degradation (GO:0000422)2.66636462
123regulation of postsynaptic membrane potential (GO:0060078)2.66267745
124sodium ion export (GO:0071436)2.66057179
125centriole assembly (GO:0098534)2.65438991
126mitochondrial fission (GO:0000266)2.64752690
127pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.63547834
128negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.63185894
129acidic amino acid transport (GO:0015800)2.62834705
130membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.62696982
131chemosensory behavior (GO:0007635)2.62490145
132left/right axis specification (GO:0070986)2.61405858
133cerebral cortex neuron differentiation (GO:0021895)2.60821613
134cellular biogenic amine biosynthetic process (GO:0042401)2.60399899
135cellular component assembly involved in morphogenesis (GO:0010927)2.59873567
136positive regulation of mitochondrial fission (GO:0090141)2.59609475
137neurotransmitter transport (GO:0006836)2.59260305
138transmission of nerve impulse (GO:0019226)2.58850551
139locomotory exploration behavior (GO:0035641)2.58810585
140C4-dicarboxylate transport (GO:0015740)2.58404132
141regulation of neurotransmitter secretion (GO:0046928)2.57935651
142membrane depolarization (GO:0051899)2.57228750
143positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.56686154
144phosphatidylglycerol biosynthetic process (GO:0006655)2.56642303
145regulation of glutamate receptor signaling pathway (GO:1900449)2.55099226
146primary amino compound metabolic process (GO:1901160)2.54432374
147phosphatidylethanolamine biosynthetic process (GO:0006646)2.54195660
148axoneme assembly (GO:0035082)2.53096795
149regulation of meiosis (GO:0040020)2.52701605
150nucleus organization (GO:0006997)2.51995772
151lactate metabolic process (GO:0006089)2.46597923
152protein refolding (GO:0042026)2.46478608
153protein localization to synapse (GO:0035418)2.43650328
154RNA localization (GO:0006403)2.43108688
155polyamine biosynthetic process (GO:0006596)2.42720634
156glycolytic process (GO:0006096)2.42706507
157regulation of short-term neuronal synaptic plasticity (GO:0048172)2.41463605
158response to acidic pH (GO:0010447)2.38862684
159sequestering of actin monomers (GO:0042989)2.36129078
160female gamete generation (GO:0007292)2.35488309
161sperm motility (GO:0030317)10.7168991

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.17343818
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse5.86457366
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.25340376
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.97014245
5PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.80252834
6GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.79616318
7BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.56487720
8GATA1_26923725_Chip-Seq_HPCs_Mouse2.24004933
9REST_21632747_ChIP-Seq_MESCs_Mouse2.17778578
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.03157854
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.02743292
12EZH2_27304074_Chip-Seq_ESCs_Mouse1.97511329
13ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.96990873
14* CTCF_27219007_Chip-Seq_Bcells_Human1.92245824
15JARID2_20075857_ChIP-Seq_MESCs_Mouse1.89864674
16MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.89355295
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.89041608
18VDR_22108803_ChIP-Seq_LS180_Human1.88979382
19EED_16625203_ChIP-ChIP_MESCs_Mouse1.85686822
20STAT6_21828071_ChIP-Seq_BEAS2B_Human1.80398256
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.80136588
22SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.78321513
23JARID2_20064375_ChIP-Seq_MESCs_Mouse1.74515547
24CTBP2_25329375_ChIP-Seq_LNCAP_Human1.74422897
25* EZH2_18974828_ChIP-Seq_MESCs_Mouse1.73876027
26* RNF2_18974828_ChIP-Seq_MESCs_Mouse1.73876027
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.73789663
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.69960383
29* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.69553340
30SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.68675266
31TAF15_26573619_Chip-Seq_HEK293_Human1.66323496
32SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.64497411
33ELK4_26923725_Chip-Seq_MESODERM_Mouse1.61288833
34MTF2_20144788_ChIP-Seq_MESCs_Mouse1.58974206
35CTCF_20526341_ChIP-Seq_ESCs_Human1.58896980
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.55392666
37KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.53615546
38GBX2_23144817_ChIP-Seq_PC3_Human1.52721882
39ZNF274_21170338_ChIP-Seq_K562_Hela1.52036478
40TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.51713640
41ELF1_20517297_ChIP-Seq_JURKAT_Human1.48857917
42P68_20966046_ChIP-Seq_HELA_Human1.48854099
43RNF2_27304074_Chip-Seq_NSC_Mouse1.41484228
44EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.41268124
45STAT1_17558387_ChIP-Seq_HELA_Human1.39813285
46EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.39660588
47KDM2B_26808549_Chip-Seq_REH_Human1.39227715
48WDR5_24793694_ChIP-Seq_LNCAP_Human1.38802159
49FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37935508
50SMC4_20622854_ChIP-Seq_HELA_Human1.37658681
51CBP_20019798_ChIP-Seq_JUKART_Human1.37628435
52IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37628435
53RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.36174203
54KAP1_22055183_ChIP-Seq_ESCs_Mouse1.35852477
55TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34312645
56POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.34312645
57* TET1_21490601_ChIP-Seq_MESCs_Mouse1.33961704
58SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.33560169
59SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.33087185
60SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.32882545
61TET1_21451524_ChIP-Seq_MESCs_Mouse1.32734463
62TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.32608257
63ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.32588499
64REST_18959480_ChIP-ChIP_MESCs_Mouse1.31163400
65TAL1_26923725_Chip-Seq_HPCs_Mouse1.31100024
66SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.29418677
67RUNX1_26923725_Chip-Seq_HPCs_Mouse1.29235272
68ZFP57_27257070_Chip-Seq_ESCs_Mouse1.27083049
69* RARB_27405468_Chip-Seq_BRAIN_Mouse1.26777480
70PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26123034
71SUZ12_27294783_Chip-Seq_ESCs_Mouse1.25961607
72BCL6_27268052_Chip-Seq_Bcells_Human1.25659393
73RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.25276232
74NANOG_18555785_Chip-Seq_ESCs_Mouse1.24858679
75FLI1_21867929_ChIP-Seq_TH2_Mouse1.22727022
76* ERA_21632823_ChIP-Seq_H3396_Human1.22529824
77PHF8_20622854_ChIP-Seq_HELA_Human1.22211613
78FUS_26573619_Chip-Seq_HEK293_Human1.21691344
79SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.21503809
80SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20291321
81GATA3_21867929_ChIP-Seq_TH1_Mouse1.19849417
82VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.19517523
83SMAD4_21799915_ChIP-Seq_A2780_Human1.19489240
84* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.19353474
85* SA1_27219007_Chip-Seq_Bcells_Human1.18103036
86BMI1_23680149_ChIP-Seq_NPCS_Mouse1.17909914
87GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.17769748
88E2F1_20622854_ChIP-Seq_HELA_Human1.17734583
89GATA3_21867929_ChIP-Seq_CD8_Mouse1.17153316
90TAF2_19829295_ChIP-Seq_ESCs_Human1.17030718
91NFE2_27457419_Chip-Seq_LIVER_Mouse1.16994442
92CBX2_27304074_Chip-Seq_ESCs_Mouse1.16770720
93DNAJC2_21179169_ChIP-ChIP_NT2_Human1.16736005
94RAC3_21632823_ChIP-Seq_H3396_Human1.16673319
95IKZF1_21737484_ChIP-ChIP_HCT116_Human1.16451556
96YY1_22570637_ChIP-Seq_MALME-3M_Human1.16448823
97* LXR_22292898_ChIP-Seq_THP-1_Human1.16115984
98RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.15508486
99MYC_19829295_ChIP-Seq_ESCs_Human1.15061383
100CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.13748408
101FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12330732
102SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.12078745
103OCT4_20526341_ChIP-Seq_ESCs_Human1.11353056
104RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.10893228
105SUZ12_27294783_Chip-Seq_NPCs_Mouse1.10358328
106MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.09594092
107SOX2_22085726_ChIP-Seq_NPCs_Mouse1.08779712
108ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.08681977
109AUTS2_25519132_ChIP-Seq_293T-REX_Human1.08574025
110GF1_26923725_Chip-Seq_HPCs_Mouse1.07710813
111CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07476277
112OCT4_19829295_ChIP-Seq_ESCs_Human1.06799411
113IRF1_19129219_ChIP-ChIP_H3396_Human1.05985735
114EZH2_27294783_Chip-Seq_ESCs_Mouse1.05602675
115MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05156941
116TCF4_23295773_ChIP-Seq_U87_Human1.05120877
117P53_22387025_ChIP-Seq_ESCs_Mouse1.05120366
118CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04940211
119ZFP281_18757296_ChIP-ChIP_E14_Mouse1.04323902
120CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04215511
121TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01691270
122SMAD3_21741376_ChIP-Seq_ESCs_Human1.00916919
123RING1B_27294783_Chip-Seq_ESCs_Mouse1.00904098
124CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00115288
125TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.99900320
126RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99862590
127EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.99731693
128EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.99474668
129CMYC_18555785_Chip-Seq_ESCs_Mouse0.98466994
130SMAD3_21741376_ChIP-Seq_EPCs_Human0.97600746
131* EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.96884560
132ERG_21242973_ChIP-ChIP_JURKAT_Human0.96772324
133MYC_27129775_Chip-Seq_CORNEA_Mouse0.96385481
134AR_25329375_ChIP-Seq_VCAP_Human0.95967639
135SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.95773534
136OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.95687472
137MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.95483273
138SMAD4_21741376_ChIP-Seq_EPCs_Human0.95306172
139* SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.94941639
140CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.94804579
141SA1_27219007_Chip-Seq_ERYTHROID_Human0.94418959
142FOXP1_21924763_ChIP-Seq_HESCs_Human0.94393508
143OCT4_18555785_Chip-Seq_ESCs_Mouse0.94270245
144YY1_21170310_ChIP-Seq_MESCs_Mouse0.94135897
145BCOR_27268052_Chip-Seq_Bcells_Human0.94008733
146STAT3_18555785_Chip-Seq_ESCs_Mouse0.93159822
147* TP63_22573176_ChIP-Seq_HFKS_Human0.92725843
148KLF4_18555785_Chip-Seq_ESCs_Mouse0.92551197
149PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.92105040
150LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.91543112
151UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91502638
152RNF2_27304074_Chip-Seq_ESCs_Mouse0.90581255
153SOX9_26525672_Chip-Seq_HEART_Mouse0.90390671
154STAT3_23295773_ChIP-Seq_U87_Human0.90122783
155ERG_20517297_ChIP-Seq_VCAP_Human0.89854331
156SOX2_18555785_Chip-Seq_ESCs_Mouse0.89852459
157CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.89634011
158P53_21459846_ChIP-Seq_SAOS-2_Human0.89520255
159EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.89511055
160* TBL1_22424771_ChIP-Seq_293T_Human0.89089655
161EZH2_27294783_Chip-Seq_NPCs_Mouse0.88828399
162* DROSHA_22980978_ChIP-Seq_HELA_Human0.88584871

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive4.55853533
2MP0001929_abnormal_gametogenesis4.38364227
3MP0008877_abnormal_DNA_methylation3.94641076
4MP0004859_abnormal_synaptic_plasticity3.47306552
5MP0003646_muscle_fatigue2.94394082
6MP0002822_catalepsy2.89774450
7MP0003880_abnormal_central_pattern2.89473223
8MP0002653_abnormal_ependyma_morphology2.79042595
9MP0002210_abnormal_sex_determination2.76175776
10MP0002161_abnormal_fertility/fecundity2.74303791
11MP0003635_abnormal_synaptic_transmissio2.33921389
12MP0005171_absent_coat_pigmentation2.30274092
13MP0003878_abnormal_ear_physiology2.29923493
14MP0005377_hearing/vestibular/ear_phenot2.29923493
15MP0001145_abnormal_male_reproductive2.24784393
16MP0001529_abnormal_vocalization2.23243766
17MP0000653_abnormal_sex_gland2.22388940
18MP0009046_muscle_twitch2.20929706
19MP0004270_analgesia2.12498495
20MP0003136_yellow_coat_color2.10339742
21MP0003787_abnormal_imprinting2.07869399
22MP0005410_abnormal_fertilization11.2772131
23MP0002063_abnormal_learning/memory/cond1.99081870
24MP0001968_abnormal_touch/_nociception1.93799284
25MP0005646_abnormal_pituitary_gland1.93087417
26MP0009745_abnormal_behavioral_response1.92716596
27MP0002736_abnormal_nociception_after1.80820896
28MP0002572_abnormal_emotion/affect_behav1.77221123
29MP0001984_abnormal_olfaction1.70062566
30MP0002064_seizures1.50920565
31MP0003879_abnormal_hair_cell1.49278917
32MP0005423_abnormal_somatic_nervous1.48288368
33MP0002272_abnormal_nervous_system1.47818327
34MP0002160_abnormal_reproductive_system1.45601295
35MP0005670_abnormal_white_adipose1.44549927
36MP0002734_abnormal_mechanical_nocicepti1.44465401
37MP0001486_abnormal_startle_reflex1.43124714
38MP0000372_irregular_coat_pigmentation1.41475913
39MP0002102_abnormal_ear_morphology1.29967224
40MP0004133_heterotaxia1.27553328
41MP0001485_abnormal_pinna_reflex1.27367466
42MP0001905_abnormal_dopamine_level1.24098473
43MP0001501_abnormal_sleep_pattern1.21177743
44MP0001440_abnormal_grooming_behavior1.20816100
45MP0003329_amyloid_beta_deposits1.15232179
46MP0006292_abnormal_olfactory_placode1.11697868
47MP0005253_abnormal_eye_physiology1.07807762
48MP0003699_abnormal_female_reproductive1.05572943
49MP0002067_abnormal_sensory_capabilities1.04306019
50MP0005386_behavior/neurological_phenoty1.01957171
51MP0004924_abnormal_behavior1.01957171
52MP0002557_abnormal_social/conspecific_i1.00602535
53MP0004811_abnormal_neuron_physiology0.99248312
54MP0002735_abnormal_chemical_nociception0.98155492
55MP0006276_abnormal_autonomic_nervous0.97676677
56MP0001765_abnormal_ion_homeostasis0.97492174
57MP0004233_abnormal_muscle_weight0.97487101
58MP0001502_abnormal_circadian_rhythm0.97163934
59MP0003718_maternal_effect0.95000424
60MP0003137_abnormal_impulse_conducting0.94870652
61MP0008569_lethality_at_weaning0.92650782
62MP0000026_abnormal_inner_ear0.92367817
63MP0001970_abnormal_pain_threshold0.91936762
64MP0002733_abnormal_thermal_nociception0.88724003
65MP0001299_abnormal_eye_distance/0.86941399
66MP0010094_abnormal_chromosome_stability0.84962808
67MP0000049_abnormal_middle_ear0.83978681
68MP0002751_abnormal_autonomic_nervous0.83652159
69MP0003122_maternal_imprinting0.80249339
70MP0001119_abnormal_female_reproductive0.80072305
71MP0005389_reproductive_system_phenotype0.79227239
72MP0000569_abnormal_digit_pigmentation0.78122401
73MP0003111_abnormal_nucleus_morphology0.75399022
74MP0002249_abnormal_larynx_morphology0.75325763
75MP0000955_abnormal_spinal_cord0.74963509
76MP0009697_abnormal_copulation0.74360619
77MP0006035_abnormal_mitochondrial_morpho0.74291579
78MP0002909_abnormal_adrenal_gland0.73859273
79MP0002066_abnormal_motor_capabilities/c0.73594318
80MP0004885_abnormal_endolymph0.73266389
81MP0002152_abnormal_brain_morphology0.73166711
82MP0002184_abnormal_innervation0.72110746
83MP0009278_abnormal_bone_marrow0.71745514
84MP0001348_abnormal_lacrimal_gland0.70595024
85MP0005499_abnormal_olfactory_system0.69900538
86MP0005394_taste/olfaction_phenotype0.69900538
87MP0008932_abnormal_embryonic_tissue0.69641300
88MP0003121_genomic_imprinting0.69541966
89MP0002882_abnormal_neuron_morphology0.69418006
90MP0002234_abnormal_pharynx_morphology0.68541427
91MP0005551_abnormal_eye_electrophysiolog0.67919532
92MP0010386_abnormal_urinary_bladder0.66747887
93MP0005084_abnormal_gallbladder_morpholo0.66391632
94MP0003283_abnormal_digestive_organ0.66231434
95MP0000631_abnormal_neuroendocrine_gland0.65325236
96MP0008872_abnormal_physiological_respon0.64219949
97MP0008995_early_reproductive_senescence0.64007972
98MP0003631_nervous_system_phenotype0.63724549
99MP0002638_abnormal_pupillary_reflex0.63382019
100MP0003633_abnormal_nervous_system0.61926242
101MP0001293_anophthalmia0.61725564
102MP0004145_abnormal_muscle_electrophysio0.58968392
103MP0005645_abnormal_hypothalamus_physiol0.58375925
104MP0002229_neurodegeneration0.56399214
105MP0005623_abnormal_meninges_morphology0.54008339
106MP0005451_abnormal_body_composition0.52951836
107MP0008058_abnormal_DNA_repair0.52596607
108MP0008874_decreased_physiological_sensi0.52467467
109MP0005310_abnormal_salivary_gland0.51464142
110MP0003861_abnormal_nervous_system0.49100060
111MP0001986_abnormal_taste_sensitivity0.48227879
112MP0000778_abnormal_nervous_system0.47041229
113MP0002876_abnormal_thyroid_physiology0.45646726
114MP0008961_abnormal_basal_metabolism0.45269122
115MP0002069_abnormal_eating/drinking_beha0.44477110
116MP0005397_hematopoietic_system_phenotyp0.44141180
117MP0001545_abnormal_hematopoietic_system0.44141180
118MP0001963_abnormal_hearing_physiology0.43523416
119MP0003123_paternal_imprinting0.42828524
120MP0003632_abnormal_nervous_system0.41992208
121MP0002752_abnormal_somatic_nervous0.41088635
122MP0001188_hyperpigmentation0.40030510
123MP0000751_myopathy0.39680431
124MP0002282_abnormal_trachea_morphology0.39523697
125MP0005535_abnormal_body_temperature0.39013584
126MP0004142_abnormal_muscle_tone0.37870249
127MP0006072_abnormal_retinal_apoptosis0.37293614
128MP0004742_abnormal_vestibular_system0.36132722

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.07631361
2Abnormal respiratory motile cilium morphology (HP:0005938)7.54022257
3Abnormal respiratory epithelium morphology (HP:0012253)7.54022257
4Infertility (HP:0000789)6.86310268
5Rhinitis (HP:0012384)6.49790474
6Abnormal ciliary motility (HP:0012262)6.35177602
7Chronic bronchitis (HP:0004469)6.12191743
8Male infertility (HP:0003251)5.59673652
9Nasal polyposis (HP:0100582)4.84862461
10Nephronophthisis (HP:0000090)4.19980602
11Bronchiectasis (HP:0002110)4.11672696
12Abnormality of the nasal mucosa (HP:0000433)3.84381653
13Bronchitis (HP:0012387)3.81967979
14Focal motor seizures (HP:0011153)3.21062675
15Abnormal spermatogenesis (HP:0008669)3.16754761
16Abnormality of the renal medulla (HP:0100957)3.10758747
17Abnormality of midbrain morphology (HP:0002418)3.06453356
18Molar tooth sign on MRI (HP:0002419)3.06453356
19Limb dystonia (HP:0002451)3.02368742
20Chronic hepatic failure (HP:0100626)2.98809339
21Amblyopia (HP:0000646)2.92060728
22Myokymia (HP:0002411)2.91920029
23Medial flaring of the eyebrow (HP:0010747)2.87723400
24Supernumerary spleens (HP:0009799)2.83422995
25Recurrent otitis media (HP:0000403)2.74050813
26Occipital encephalocele (HP:0002085)2.61687073
27Abnormal gallbladder physiology (HP:0012438)2.59560291
28Cholecystitis (HP:0001082)2.59560291
29Impulsivity (HP:0100710)2.46530829
30Cerebral hypomyelination (HP:0006808)2.34030815
31Tubulointerstitial nephritis (HP:0001970)2.32542316
32Ankle clonus (HP:0011448)2.29969130
33Recurrent sinusitis (HP:0011108)2.29351173
34Recurrent bronchitis (HP:0002837)2.28485470
35Dialeptic seizures (HP:0011146)2.24539038
36Bony spicule pigmentary retinopathy (HP:0007737)2.22925526
37Anterior segment dysgenesis (HP:0007700)2.22387983
38Delusions (HP:0000746)2.17051647
39Focal seizures (HP:0007359)2.12979001
40Hand muscle atrophy (HP:0009130)2.11495397
41Pancreatic fibrosis (HP:0100732)2.11102893
42Progressive cerebellar ataxia (HP:0002073)2.10373962
43Severe visual impairment (HP:0001141)2.10355201
44Epileptic encephalopathy (HP:0200134)2.06732548
45Gait imbalance (HP:0002141)2.06554173
46Hypoplasia of the capital femoral epiphysis (HP:0003090)2.05257968
47Impaired vibration sensation in the lower limbs (HP:0002166)2.04803300
48Respiratory insufficiency due to defective ciliary clearance (HP:0200073)11.0857357
49Absent/shortened dynein arms (HP:0200106)10.8226510
50Dynein arm defect of respiratory motile cilia (HP:0012255)10.8226510
51Azoospermia (HP:0000027)1.99879836
52Congenital primary aphakia (HP:0007707)1.98394113
53Spastic tetraparesis (HP:0001285)1.97245212
54Failure to thrive in infancy (HP:0001531)1.96748531
55Absence seizures (HP:0002121)1.96451555
56Insulin-resistant diabetes mellitus (HP:0000831)1.94893981
57Tubulointerstitial abnormality (HP:0001969)1.93739086
58Gaze-evoked nystagmus (HP:0000640)1.93018788
59Annular pancreas (HP:0001734)1.90313897
60Hyperventilation (HP:0002883)1.88874851
61Decreased central vision (HP:0007663)1.87900657
62Postaxial foot polydactyly (HP:0001830)1.87711796
63Atelectasis (HP:0100750)1.86972987
64Turricephaly (HP:0000262)1.86510065
65Abnormality of binocular vision (HP:0011514)1.86356396
66Diplopia (HP:0000651)1.86356396
67Sclerocornea (HP:0000647)1.86106698
68Dyschromatopsia (HP:0007641)1.84575648
69Abnormal rod and cone electroretinograms (HP:0008323)1.83289317
70Spastic gait (HP:0002064)1.82461543
71Renal Fanconi syndrome (HP:0001994)1.82402583
72Gonadotropin excess (HP:0000837)1.82357212
73Hemiparesis (HP:0001269)1.81651360
74Neurofibrillary tangles (HP:0002185)1.81534697
75Anencephaly (HP:0002323)1.81077938
76Choroideremia (HP:0001139)1.81036491
77Oculomotor apraxia (HP:0000657)1.80743166
78Nephrogenic diabetes insipidus (HP:0009806)1.80164543
79Aplasia/Hypoplasia of the macula (HP:0008059)1.78943108
80Transposition of the great arteries (HP:0001669)1.78708993
81Abnormal connection of the cardiac segments (HP:0011545)1.78708993
82Abnormal ventriculo-arterial connection (HP:0011563)1.78708993
83Hypoplastic left heart (HP:0004383)1.78212024
84Bell-shaped thorax (HP:0001591)1.77986657
85Hypoplasia of the thymus (HP:0000778)1.77426494
86Generalized tonic-clonic seizures (HP:0002069)1.77308291
87Visual hallucinations (HP:0002367)1.77305645
88Tubular atrophy (HP:0000092)1.77005166
89Aplasia/Hypoplasia of the lens (HP:0008063)1.75890389
90Optic nerve hypoplasia (HP:0000609)1.74466453
91Abnormality of ocular smooth pursuit (HP:0000617)1.74296816
92Aplasia/Hypoplasia of the spleen (HP:0010451)1.74191712
93Abnormality of the lower motor neuron (HP:0002366)1.73051520
94Atonic seizures (HP:0010819)1.72798345
95Amyotrophic lateral sclerosis (HP:0007354)1.71568302
96Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.71372572
97Asplenia (HP:0001746)1.70685774
98Spastic paraparesis (HP:0002313)1.69942051
99Abnormality of the parathyroid morphology (HP:0011766)1.69939462
100Impaired smooth pursuit (HP:0007772)1.69363321
101Torticollis (HP:0000473)1.67649307
102Dysmetria (HP:0001310)1.67617336
103Aplasia/Hypoplasia affecting the retina (HP:0008061)1.67161433
104Upper limb amyotrophy (HP:0009129)1.66818903
105Distal upper limb amyotrophy (HP:0007149)1.66818903
106Postaxial hand polydactyly (HP:0001162)1.66051536
107Poor coordination (HP:0002370)1.65263884
108Ependymoma (HP:0002888)1.65138612
109Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.64656553
110Action tremor (HP:0002345)1.64549411
111Resting tremor (HP:0002322)1.64419273
112Retinal dysplasia (HP:0007973)1.64390260
113Bradykinesia (HP:0002067)1.63754127
114Attenuation of retinal blood vessels (HP:0007843)1.62075525
115Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.60708713
116Absent epiphyses (HP:0010577)1.60708713
117Abnormal drinking behavior (HP:0030082)1.60191521
118Polydipsia (HP:0001959)1.60191521
119Unsteady gait (HP:0002317)1.60011743
120Urinary bladder sphincter dysfunction (HP:0002839)1.59593929
121Polyphagia (HP:0002591)1.59572354
122Decreased electroretinogram (ERG) amplitude (HP:0000654)1.58425797
123Febrile seizures (HP:0002373)1.57630140
124True hermaphroditism (HP:0010459)1.56878088
125Heterotopia (HP:0002282)1.56581704
126Genital tract atresia (HP:0001827)1.56479391
127Congenital hepatic fibrosis (HP:0002612)1.56462962
128Focal dystonia (HP:0004373)1.55748592
129Postural instability (HP:0002172)1.55125666
130Cystic liver disease (HP:0006706)1.54384877
131Bile duct proliferation (HP:0001408)1.52232138
132Abnormal biliary tract physiology (HP:0012439)1.52232138
133Abnormality of saccadic eye movements (HP:0000570)1.50949472
134Aplasia/Hypoplasia of the tongue (HP:0010295)1.46849062
135Vaginal atresia (HP:0000148)1.46638367
136Impaired vibratory sensation (HP:0002495)1.45523797
137Tubulointerstitial fibrosis (HP:0005576)1.45321553
138Abnormal eating behavior (HP:0100738)1.44800383
139Papillary thyroid carcinoma (HP:0002895)1.44765960
140Lissencephaly (HP:0001339)1.44156461
141Stage 5 chronic kidney disease (HP:0003774)1.44075932
142Bundle branch block (HP:0011710)1.43652636
143Supranuclear gaze palsy (HP:0000605)1.42963615
144Short femoral neck (HP:0100864)1.42018944
145Type II lissencephaly (HP:0007260)1.39347395
146Cerebral inclusion bodies (HP:0100314)1.39039432
147Pancreatic cysts (HP:0001737)1.37274318
148Renal dysplasia (HP:0000110)1.36438801
149Neuronal loss in central nervous system (HP:0002529)1.36172080
150Chronic sinusitis (HP:0011109)1.34079824
151Dysmetric saccades (HP:0000641)1.33828817
152Peripheral hypomyelination (HP:0007182)1.33573355
153Microglossia (HP:0000171)1.33134693
154Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.32898541

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRKD36.31112581
2PDK44.92232033
3PDK34.92232033
4TESK14.88746005
5ICK2.94351664
6PDK22.90010019
7EPHA42.73796355
8MAPK152.59460037
9TSSK62.49868874
10STK382.47985413
11MAP3K92.23029591
12RIPK42.05889858
13TIE12.02658462
14PTK2B1.98955447
15PNCK1.80905667
16NTRK31.78334899
17MAP3K41.77057891
18MUSK1.76627465
19MAP3K61.76063698
20ARAF1.71384313
21MAP4K21.70180966
22UHMK11.69374202
23KSR21.69357429
24TESK21.58353434
25MAP2K71.55569734
26BRAF1.53944484
27BMPR21.48381234
28DYRK21.45609240
29TAOK11.45347527
30EEF2K1.44835641
31NTRK21.42568482
32INSRR1.40839462
33MAP3K131.38002368
34GRK51.30192063
35TYRO31.27551456
36CSNK1G21.27081162
37RAF11.26769912
38NEK21.23894727
39KDR1.23083935
40CSNK1G31.22137944
41OXSR11.19528111
42MAP3K111.19002780
43PAK61.17994417
44MAP3K121.13289336
45CAMKK21.12606121
46PDK11.11656931
47MAPK131.09596481
48LATS21.08117711
49DDR21.07494246
50CCNB11.07036259
51WNK41.02975736
52DYRK1A1.02116114
53TTK1.01789058
54PLK40.99908140
55PINK10.98058830
56CSNK1A1L0.93292370
57STK38L0.93142669
58CAMK40.92269027
59LIMK10.90784345
60CAMKK10.90746134
61ZAK0.89553004
62MOS0.88419427
63TNIK0.85759557
64CHEK20.85679285
65MAP2K40.85487541
66DYRK30.85182826
67BRD40.84731575
68MARK20.83508796
69PDPK10.83317196
70PHKG20.81735013
71PHKG10.81735013
72CDC70.79607077
73MINK10.78925298
74STK390.78849228
75MAPKAPK50.78448323
76TAOK30.76414513
77CSNK1G10.74531315
78AURKA0.70675474
79DAPK30.68092970
80KSR10.67904743
81DAPK20.67759854
82BRSK10.67466274
83PKN10.66879012
84CDK190.65720520
85LATS10.64333738
86DAPK10.63810659
87FES0.62647157
88PLK30.62038362
89DYRK1B0.61577666
90VRK10.60161863
91CAMK1D0.58948564
92MARK10.58654145
93ERBB40.58258601
94PRKCG0.56595302
95VRK20.56578981
96CDK150.54061552
97CDK50.53681677
98CDK180.53360976
99WNK30.51013439
100NEK60.50817028
101CASK0.48744814
102PRKD20.48667119
103RPS6KA20.47611821
104ABL20.47408413
105MAP3K10.46715827
106CDK11A0.46123824
107STK110.43679102
108BCKDK0.43575170
109MAPK100.43486440
110PRKG10.42910796
111CDK80.42485811
112CSNK1A10.41012284
113PRKG20.40975358
114CDK20.40546525
115SGK20.40073027
116SRPK10.39625870
117CAMK2B0.38791800
118CAMK2G0.38606186
119CDK70.38460074
120STK30.38414307
121PLK20.37274371
122CDK140.35864281
123MAP2K60.33796716
124CDK30.33458319
125MAPKAPK30.32847544
126CHEK10.32344656
127* CAMK2A0.30273671
128SIK20.29937425
129CAMK10.29409422
130MAP3K50.29347562
131SGK4940.27968739
132SGK2230.27968739
133PRKAA10.26862282
134NTRK10.25200808
135PLK10.24931749
136PRPF4B0.24828734
137RET0.23913501
138PAK10.23667390
139CAMK1G0.23346422
140TNK20.23221519
141BRSK20.22673384
142CDK90.21632873
143ATM0.21473883
144RPS6KB10.20390563
145WNK10.19025425
146PRKCZ0.17556930

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.87623341
2Amphetamine addiction_Homo sapiens_hsa050312.85003129
3Synaptic vesicle cycle_Homo sapiens_hsa047212.59284103
4Olfactory transduction_Homo sapiens_hsa047402.56318983
5Long-term potentiation_Homo sapiens_hsa047202.49871821
6Oocyte meiosis_Homo sapiens_hsa041142.27635814
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.21931287
8Circadian entrainment_Homo sapiens_hsa047132.18117147
9Fatty acid biosynthesis_Homo sapiens_hsa000612.17993191
10Vitamin B6 metabolism_Homo sapiens_hsa007502.12173981
11Basal transcription factors_Homo sapiens_hsa030222.09425205
12Oxidative phosphorylation_Homo sapiens_hsa001902.04466753
13Glutamatergic synapse_Homo sapiens_hsa047242.02911176
14Parkinsons disease_Homo sapiens_hsa050122.00097076
152-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.90654654
16Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.89405509
17Morphine addiction_Homo sapiens_hsa050321.88803469
18Base excision repair_Homo sapiens_hsa034101.85698161
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.83796057
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.81230132
21Insulin secretion_Homo sapiens_hsa049111.80026219
22Dorso-ventral axis formation_Homo sapiens_hsa043201.76328296
23Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.74971752
24Linoleic acid metabolism_Homo sapiens_hsa005911.74844694
25Cocaine addiction_Homo sapiens_hsa050301.74265653
26Dopaminergic synapse_Homo sapiens_hsa047281.73032410
27Salivary secretion_Homo sapiens_hsa049701.69287605
28Renin secretion_Homo sapiens_hsa049241.68356984
29Glucagon signaling pathway_Homo sapiens_hsa049221.66346630
30Carbohydrate digestion and absorption_Homo sapiens_hsa049731.60202614
31Taste transduction_Homo sapiens_hsa047421.51539500
32Calcium signaling pathway_Homo sapiens_hsa040201.50133408
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.45446728
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.44412528
35Alzheimers disease_Homo sapiens_hsa050101.43710113
36GABAergic synapse_Homo sapiens_hsa047271.42876315
37Glycerophospholipid metabolism_Homo sapiens_hsa005641.42602453
38Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.40594578
39Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.34984400
40Gastric acid secretion_Homo sapiens_hsa049711.32401119
41Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.32074017
42Collecting duct acid secretion_Homo sapiens_hsa049661.31236801
43Estrogen signaling pathway_Homo sapiens_hsa049151.29533743
44DNA replication_Homo sapiens_hsa030301.27172434
45cAMP signaling pathway_Homo sapiens_hsa040241.26859878
46Oxytocin signaling pathway_Homo sapiens_hsa049211.25150583
47Ether lipid metabolism_Homo sapiens_hsa005651.24181150
48Cholinergic synapse_Homo sapiens_hsa047251.23832487
49Phosphatidylinositol signaling system_Homo sapiens_hsa040701.22310153
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.21936667
51Mismatch repair_Homo sapiens_hsa034301.18950703
52Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.17890052
53Biosynthesis of amino acids_Homo sapiens_hsa012301.16354850
54Pyruvate metabolism_Homo sapiens_hsa006201.15135571
55Arginine and proline metabolism_Homo sapiens_hsa003301.14971029
56Fanconi anemia pathway_Homo sapiens_hsa034601.14039294
57Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.13707451
58Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.12739006
59Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.12191445
60cGMP-PKG signaling pathway_Homo sapiens_hsa040221.09799645
61Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.09124699
62GnRH signaling pathway_Homo sapiens_hsa049121.08419515
63Ovarian steroidogenesis_Homo sapiens_hsa049131.07561668
64Long-term depression_Homo sapiens_hsa047301.06350354
65Serotonergic synapse_Homo sapiens_hsa047261.05307097
66Axon guidance_Homo sapiens_hsa043601.04690997
67RNA degradation_Homo sapiens_hsa030181.03685143
68Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.03660206
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.03654839
70Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.99876846
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.99436954
72Phenylalanine metabolism_Homo sapiens_hsa003600.97655579
73Circadian rhythm_Homo sapiens_hsa047100.97303584
74Carbon metabolism_Homo sapiens_hsa012000.96010758
75Cardiac muscle contraction_Homo sapiens_hsa042600.93482961
76Sulfur relay system_Homo sapiens_hsa041220.91843663
77Folate biosynthesis_Homo sapiens_hsa007900.89196569
78RNA polymerase_Homo sapiens_hsa030200.87832937
79Glycerolipid metabolism_Homo sapiens_hsa005610.87583160
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82227428
81Inositol phosphate metabolism_Homo sapiens_hsa005620.81797023
82VEGF signaling pathway_Homo sapiens_hsa043700.80461980
83Thyroid hormone synthesis_Homo sapiens_hsa049180.79634213
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.78868580
85Purine metabolism_Homo sapiens_hsa002300.78808088
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.76199038
87Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.75521371
88mRNA surveillance pathway_Homo sapiens_hsa030150.74795738
89Type II diabetes mellitus_Homo sapiens_hsa049300.70552024
90Regulation of autophagy_Homo sapiens_hsa041400.70480213
91Cell cycle_Homo sapiens_hsa041100.68968181
92Gap junction_Homo sapiens_hsa045400.68383847
93Alcoholism_Homo sapiens_hsa050340.67872478
94Butanoate metabolism_Homo sapiens_hsa006500.64681413
95Pyrimidine metabolism_Homo sapiens_hsa002400.64304450
96Tight junction_Homo sapiens_hsa045300.64111634
97Fatty acid elongation_Homo sapiens_hsa000620.64109351
98Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64022391
99Pancreatic secretion_Homo sapiens_hsa049720.63978366
100Huntingtons disease_Homo sapiens_hsa050160.62137489
101Choline metabolism in cancer_Homo sapiens_hsa052310.61843706
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.61605073
103MAPK signaling pathway_Homo sapiens_hsa040100.60808669
104Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58976064
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.57891956
106Tyrosine metabolism_Homo sapiens_hsa003500.57698829
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.57570886
108Mineral absorption_Homo sapiens_hsa049780.55502970
109Glioma_Homo sapiens_hsa052140.53688366
110Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.53335309
111Fatty acid metabolism_Homo sapiens_hsa012120.52202151
112Metabolic pathways_Homo sapiens_hsa011000.49606407
113ErbB signaling pathway_Homo sapiens_hsa040120.49452384
114Endocytosis_Homo sapiens_hsa041440.46517254
115Protein export_Homo sapiens_hsa030600.45822083
116Fatty acid degradation_Homo sapiens_hsa000710.44924323
117Fructose and mannose metabolism_Homo sapiens_hsa000510.44724897
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43734481
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43060905
120Melanogenesis_Homo sapiens_hsa049160.42207754
121RNA transport_Homo sapiens_hsa030130.41634725
122Hippo signaling pathway_Homo sapiens_hsa043900.40397993
123Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39597377
124Peroxisome_Homo sapiens_hsa041460.38896215
125Prion diseases_Homo sapiens_hsa050200.38783801
126Ras signaling pathway_Homo sapiens_hsa040140.38280572
127Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.37343203
128beta-Alanine metabolism_Homo sapiens_hsa004100.37175548
129Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.36875228
130Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.36499651
131Hedgehog signaling pathway_Homo sapiens_hsa043400.35483907
132Phototransduction_Homo sapiens_hsa047440.34753689
133Wnt signaling pathway_Homo sapiens_hsa043100.34373407
134Type I diabetes mellitus_Homo sapiens_hsa049400.34156916
135Dilated cardiomyopathy_Homo sapiens_hsa054140.34149063
136Cysteine and methionine metabolism_Homo sapiens_hsa002700.32379823
137Propanoate metabolism_Homo sapiens_hsa006400.31221009
138Arginine biosynthesis_Homo sapiens_hsa002200.30227335
139Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30082861
140Ribosome_Homo sapiens_hsa030100.29522150
141Glycosaminoglycan degradation_Homo sapiens_hsa005310.29403527
142Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.29344674
143Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.29272918
144Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.24766067
145Vibrio cholerae infection_Homo sapiens_hsa051100.24738599
146Pentose phosphate pathway_Homo sapiens_hsa000300.24338328

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