KIF21A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)4.75255757
2positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.58008183
3pyrimidine nucleobase catabolic process (GO:0006208)4.57780465
4synaptic vesicle exocytosis (GO:0016079)4.47460225
5neuron cell-cell adhesion (GO:0007158)4.41088515
6neuronal action potential propagation (GO:0019227)4.36686209
7glutamate secretion (GO:0014047)4.28711945
8synaptic vesicle maturation (GO:0016188)4.23885134
9vocalization behavior (GO:0071625)4.11438332
10regulation of synaptic vesicle exocytosis (GO:2000300)4.10306601
11postsynaptic membrane organization (GO:0001941)4.02309501
12locomotory exploration behavior (GO:0035641)3.83190350
13protein localization to synapse (GO:0035418)3.82808628
14nucleobase catabolic process (GO:0046113)3.82105895
15positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.76660165
16neurotransmitter secretion (GO:0007269)3.66676531
17regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.66353936
18regulation of synaptic vesicle transport (GO:1902803)3.58232248
19positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.53068390
20auditory behavior (GO:0031223)3.47817956
21neuron recognition (GO:0008038)3.45934226
22ionotropic glutamate receptor signaling pathway (GO:0035235)3.45652127
23regulation of glutamate receptor signaling pathway (GO:1900449)3.42196880
24epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.36660132
25transmission of nerve impulse (GO:0019226)3.35247867
26regulation of neuronal synaptic plasticity (GO:0048168)3.32772689
27layer formation in cerebral cortex (GO:0021819)3.31217880
28gamma-aminobutyric acid transport (GO:0015812)3.27827904
29cerebellar Purkinje cell differentiation (GO:0021702)3.27713179
30membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.25587331
31exploration behavior (GO:0035640)3.25260947
32neuron-neuron synaptic transmission (GO:0007270)3.25147378
33neurotransmitter transport (GO:0006836)3.24205663
34glutamate receptor signaling pathway (GO:0007215)3.23652006
35positive regulation of dendritic spine morphogenesis (GO:0061003)3.23497895
36mating behavior (GO:0007617)3.23415348
37synaptic transmission, glutamatergic (GO:0035249)3.20971656
38cell migration in hindbrain (GO:0021535)3.20190510
39regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.18784306
40axonal fasciculation (GO:0007413)3.18028428
41central nervous system projection neuron axonogenesis (GO:0021952)3.17285173
42cilium movement (GO:0003341)3.17016349
43membrane depolarization during action potential (GO:0086010)3.16490143
44proline transport (GO:0015824)3.16345123
45regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.15203796
46cerebral cortex radially oriented cell migration (GO:0021799)3.14755994
47mechanosensory behavior (GO:0007638)3.12982904
48presynaptic membrane assembly (GO:0097105)3.10432448
49synaptic vesicle docking involved in exocytosis (GO:0016081)3.10049663
50regulation of long-term neuronal synaptic plasticity (GO:0048169)3.09404842
51regulation of vesicle fusion (GO:0031338)3.09081004
52axonemal dynein complex assembly (GO:0070286)3.08199780
53epithelial cilium movement (GO:0003351)3.07943053
54cilium or flagellum-dependent cell motility (GO:0001539)3.07913808
55neuromuscular process controlling posture (GO:0050884)3.06784048
56behavioral response to nicotine (GO:0035095)3.04697049
57presynaptic membrane organization (GO:0097090)3.04131059
58cellular potassium ion homeostasis (GO:0030007)3.03683220
59central nervous system myelination (GO:0022010)3.02688994
60axon ensheathment in central nervous system (GO:0032291)3.02688994
61dendritic spine morphogenesis (GO:0060997)3.00950308
62innervation (GO:0060384)2.97979223
63limb bud formation (GO:0060174)2.97027986
64regulation of neurotransmitter levels (GO:0001505)2.93477469
65gamma-aminobutyric acid signaling pathway (GO:0007214)2.92721918
66startle response (GO:0001964)2.92564135
67neuronal action potential (GO:0019228)2.90214094
68negative regulation of dendrite morphogenesis (GO:0050774)2.88531028
69neuronal ion channel clustering (GO:0045161)2.87691547
70synaptic vesicle endocytosis (GO:0048488)2.86945137
71regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.86069638
72negative regulation of synaptic transmission, GABAergic (GO:0032229)2.85483384
73positive regulation of potassium ion transmembrane transport (GO:1901381)2.84531784
74regulation of excitatory postsynaptic membrane potential (GO:0060079)2.83120794
75dendrite morphogenesis (GO:0048813)2.82913846
76neurofilament cytoskeleton organization (GO:0060052)2.82461699
77regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.81601215
78synapse assembly (GO:0007416)2.81063670
79response to auditory stimulus (GO:0010996)2.80289562
80regulation of neurotransmitter secretion (GO:0046928)2.79955821
81activation of protein kinase A activity (GO:0034199)2.78637528
82positive regulation of synaptic transmission, GABAergic (GO:0032230)2.78553298
83regulation of postsynaptic membrane potential (GO:0060078)2.78186697
84apical protein localization (GO:0045176)2.77687151
85regulation of synapse structural plasticity (GO:0051823)2.77389214
86glycine transport (GO:0015816)2.76733753
87central nervous system neuron axonogenesis (GO:0021955)2.76587976
88nonmotile primary cilium assembly (GO:0035058)2.75740791
89vesicle transport along microtubule (GO:0047496)2.75359929
90adult walking behavior (GO:0007628)2.75340497
91neurotransmitter-gated ion channel clustering (GO:0072578)2.75011426
92negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.74679331
93positive regulation of synapse assembly (GO:0051965)2.74165149
94membrane hyperpolarization (GO:0060081)2.73550363
95retinal ganglion cell axon guidance (GO:0031290)2.72623872
96membrane depolarization (GO:0051899)2.72062846
97regulation of synaptic transmission, glutamatergic (GO:0051966)2.71126434
98organelle transport along microtubule (GO:0072384)2.70865441
99positive regulation of potassium ion transport (GO:0043268)2.67547395
100long-term memory (GO:0007616)2.66516161
101regulation of synaptic plasticity (GO:0048167)2.66396941
102mitochondrion transport along microtubule (GO:0047497)2.65615618
103establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.65615618
104calcium-mediated signaling using intracellular calcium source (GO:0035584)2.65476640
105behavioral response to cocaine (GO:0048148)2.63757052
106cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.63697794
107regulation of neurotransmitter transport (GO:0051588)2.63393822
108positive regulation of membrane potential (GO:0045838)2.63319153
109negative regulation of neurotransmitter transport (GO:0051589)2.62944661
110negative regulation of dendrite development (GO:2000171)2.61501135
111long-term synaptic potentiation (GO:0060291)2.61218842
112cerebellar granule cell differentiation (GO:0021707)2.60297979
113regulation of dendritic spine morphogenesis (GO:0061001)2.60118447
114synaptic transmission (GO:0007268)2.60015491
115neuromuscular process controlling balance (GO:0050885)2.59784247
116synapse organization (GO:0050808)2.59039141
117short-term memory (GO:0007614)2.58716037
118axon cargo transport (GO:0008088)2.58470145
119negative regulation of cytosolic calcium ion concentration (GO:0051481)2.57813526
120long-chain fatty acid biosynthetic process (GO:0042759)2.57581005
121sympathetic nervous system development (GO:0048485)2.57563129
122G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.57465443
123prepulse inhibition (GO:0060134)2.56172118
124sodium ion export (GO:0071436)2.55962843
125chemosensory behavior (GO:0007635)2.55903742
126establishment of nucleus localization (GO:0040023)2.55894903
127neuromuscular synaptic transmission (GO:0007274)2.55831951
128suckling behavior (GO:0001967)2.55773135
129positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.55556350
130establishment of mitochondrion localization (GO:0051654)2.54904318
131positive regulation of dendritic spine development (GO:0060999)2.54811573
132intraciliary transport (GO:0042073)2.48172863
133protein localization to cilium (GO:0061512)2.42785540
134calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.41644706
135C4-dicarboxylate transport (GO:0015740)2.41178893
136axonogenesis (GO:0007409)2.40729895
137regulation of cilium movement (GO:0003352)2.40483531
138cilium assembly (GO:0042384)2.40039233
139cilium organization (GO:0044782)2.39399868
140cochlea development (GO:0090102)2.39353437
141hippocampus development (GO:0021766)2.36278188
142behavioral defense response (GO:0002209)2.35959831
143behavioral fear response (GO:0001662)2.35959831
144regulation of synapse assembly (GO:0051963)2.35302706

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.91561556
2GBX2_23144817_ChIP-Seq_PC3_Human3.46869410
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.91256641
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.86176773
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.79606816
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.50634671
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.50634671
8* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.46846239
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.43594256
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.41228925
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.36598111
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.35198822
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.34464390
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.32734062
15TAF15_26573619_Chip-Seq_HEK293_Human2.31434328
16REST_21632747_ChIP-Seq_MESCs_Mouse2.28949676
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.23267626
18SALL1_21062744_ChIP-ChIP_HESCs_Human2.18652006
19RBPJ_22232070_ChIP-Seq_NCS_Mouse2.17761077
20SUZ12_27294783_Chip-Seq_ESCs_Mouse2.09078043
21* EZH2_27294783_Chip-Seq_ESCs_Mouse2.08205957
22DROSHA_22980978_ChIP-Seq_HELA_Human2.00716839
23* RNF2_27304074_Chip-Seq_ESCs_Mouse1.99485047
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.95768356
25CTBP2_25329375_ChIP-Seq_LNCAP_Human1.87323122
26REST_18959480_ChIP-ChIP_MESCs_Mouse1.87322738
27AR_21572438_ChIP-Seq_LNCaP_Human1.84230345
28NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.81680875
29RARB_27405468_Chip-Seq_BRAIN_Mouse1.80487638
30HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.75666870
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.75396939
32* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.73164142
33* SMAD4_21799915_ChIP-Seq_A2780_Human1.69628868
34BMI1_23680149_ChIP-Seq_NPCS_Mouse1.64323477
35ZFP57_27257070_Chip-Seq_ESCs_Mouse1.64319395
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.61092509
37EWS_26573619_Chip-Seq_HEK293_Human1.57499826
38P300_19829295_ChIP-Seq_ESCs_Human1.55540211
39CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.52705404
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.49708605
41NR3C1_23031785_ChIP-Seq_PC12_Mouse1.46464070
42SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46219101
43SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44272781
44TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44061428
45OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.42971779
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.42892601
47IGF1R_20145208_ChIP-Seq_DFB_Human1.37209464
48* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.37183092
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36198888
50CDX2_19796622_ChIP-Seq_MESCs_Mouse1.35801089
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.35698792
52SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35440775
53ERG_21242973_ChIP-ChIP_JURKAT_Human1.34621089
54GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.33049148
55* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.32045054
56VDR_22108803_ChIP-Seq_LS180_Human1.29990777
57ZNF274_21170338_ChIP-Seq_K562_Hela1.29421517
58SOX2_21211035_ChIP-Seq_LN229_Gbm1.28936364
59IKZF1_21737484_ChIP-ChIP_HCT116_Human1.28450237
60STAT3_23295773_ChIP-Seq_U87_Human1.27197843
61POU3F2_20337985_ChIP-ChIP_501MEL_Human1.25632530
62AR_25329375_ChIP-Seq_VCAP_Human1.23453477
63AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.23190825
64ZNF217_24962896_ChIP-Seq_MCF-7_Human1.22850859
65AHR_22903824_ChIP-Seq_MCF-7_Human1.20697082
66RNF2_27304074_Chip-Seq_NSC_Mouse1.19877695
67SOX9_26525672_Chip-Seq_HEART_Mouse1.19647908
68MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.19065753
69* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.18533002
70IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17797904
71CBP_20019798_ChIP-Seq_JUKART_Human1.17797904
72ARNT_22903824_ChIP-Seq_MCF-7_Human1.16893263
73RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.16482707
74* RING1B_27294783_Chip-Seq_ESCs_Mouse1.14961086
75TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.13612127
76* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.10882739
77MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10636268
78WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08714084
79TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.08705328
80CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.08564918
81TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07859892
82POU5F1_16153702_ChIP-ChIP_HESCs_Human1.07813249
83AR_19668381_ChIP-Seq_PC3_Human1.07142355
84* TCF4_23295773_ChIP-Seq_U87_Human1.07043721
85UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06677843
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.06486628
87PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.06390732
88TAL1_26923725_Chip-Seq_HPCs_Mouse1.02621957
89BCAT_22108803_ChIP-Seq_LS180_Human1.02250118
90* RUNX2_22187159_ChIP-Seq_PCA_Human1.01689388
91* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.01113937
92P53_22127205_ChIP-Seq_FIBROBLAST_Human1.01054392
93P53_22387025_ChIP-Seq_ESCs_Mouse1.01015473
94RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.00047836
95NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99778340
96KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98746488
97* RING1B_27294783_Chip-Seq_NPCs_Mouse0.98340661
98RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.97682206
99FUS_26573619_Chip-Seq_HEK293_Human0.96833685
100YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96684527
101TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96511513
102PRDM14_20953172_ChIP-Seq_ESCs_Human0.96291249
103ER_23166858_ChIP-Seq_MCF-7_Human0.96123683
104SMAD4_21741376_ChIP-Seq_HESCs_Human0.95994208
105MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.95683555
106TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.94782632
107NANOG_18555785_Chip-Seq_ESCs_Mouse0.94701339
108MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.94013460
109SMAD3_21741376_ChIP-Seq_ESCs_Human0.93606572
110TP53_18474530_ChIP-ChIP_U2OS_Human0.92500981
111EP300_21415370_ChIP-Seq_HL-1_Mouse0.88902087
112LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87388951
113TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87094598
114POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.87094598
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.86635279
116DNAJC2_21179169_ChIP-ChIP_NT2_Human0.85727824
117* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.85281366
118SMAD4_21741376_ChIP-Seq_EPCs_Human0.84465415

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.44963837
2MP0003880_abnormal_central_pattern4.38747808
3MP0004270_analgesia3.88542632
4MP0003635_abnormal_synaptic_transmissio3.30280145
5MP0001968_abnormal_touch/_nociception3.24307284
6MP0002735_abnormal_chemical_nociception2.96684086
7MP0002734_abnormal_mechanical_nocicepti2.83375786
8MP0009745_abnormal_behavioral_response2.80106259
9MP0009046_muscle_twitch2.79398380
10MP0006276_abnormal_autonomic_nervous2.76244506
11MP0002064_seizures2.73976146
12MP0002063_abnormal_learning/memory/cond2.60427555
13MP0002736_abnormal_nociception_after2.60094007
14MP0002272_abnormal_nervous_system2.59300328
15MP0002733_abnormal_thermal_nociception2.40591624
16MP0002572_abnormal_emotion/affect_behav2.37402830
17MP0005423_abnormal_somatic_nervous2.35333308
18MP0001486_abnormal_startle_reflex2.28237364
19MP0002822_catalepsy2.23989966
20MP0001970_abnormal_pain_threshold2.12325519
21MP0001440_abnormal_grooming_behavior2.02990289
22MP0002067_abnormal_sensory_capabilities1.99397221
23MP0001501_abnormal_sleep_pattern1.98451799
24MP0003329_amyloid_beta_deposits1.97883698
25MP0000778_abnormal_nervous_system1.96660303
26MP0000566_synostosis1.93351414
27MP0002184_abnormal_innervation1.89940150
28MP0004858_abnormal_nervous_system1.89757926
29MP0000569_abnormal_digit_pigmentation1.82843255
30MP0003121_genomic_imprinting1.78186431
31MP0009780_abnormal_chondrocyte_physiolo1.70963417
32MP0001984_abnormal_olfaction1.70546119
33MP0001529_abnormal_vocalization1.68769243
34MP0005646_abnormal_pituitary_gland1.63934967
35MP0004924_abnormal_behavior1.63685788
36MP0005386_behavior/neurological_phenoty1.63685788
37MP0002909_abnormal_adrenal_gland1.61735234
38MP0000955_abnormal_spinal_cord1.59960289
39MP0002557_abnormal_social/conspecific_i1.56662781
40MP0008569_lethality_at_weaning1.51024547
41MP0001905_abnormal_dopamine_level1.50191333
42MP0005645_abnormal_hypothalamus_physiol1.49842801
43MP0004811_abnormal_neuron_physiology1.46103345
44MP0004142_abnormal_muscle_tone1.45079855
45MP0002882_abnormal_neuron_morphology1.45071269
46MP0008877_abnormal_DNA_methylation1.42101188
47MP0003122_maternal_imprinting1.40749879
48MP0004885_abnormal_endolymph1.40059731
49MP0003136_yellow_coat_color1.36725021
50MP0004133_heterotaxia1.34017978
51MP0003890_abnormal_embryonic-extraembry1.33281522
52MP0002066_abnormal_motor_capabilities/c1.32103692
53MP0005187_abnormal_penis_morphology1.30513441
54MP0005551_abnormal_eye_electrophysiolog1.28492019
55MP0005248_abnormal_Harderian_gland1.28194582
56MP0003123_paternal_imprinting1.26195035
57MP0002653_abnormal_ependyma_morphology1.26057458
58MP0002229_neurodegeneration1.25655224
59MP0004742_abnormal_vestibular_system1.22361224
60MP0000920_abnormal_myelination1.20709773
61MP0001502_abnormal_circadian_rhythm1.20293801
62MP0002837_dystrophic_cardiac_calcinosis1.19846653
63MP0003633_abnormal_nervous_system1.18963132
64MP0002102_abnormal_ear_morphology1.16935368
65MP0008789_abnormal_olfactory_epithelium1.15649565
66MP0006292_abnormal_olfactory_placode1.15214440
67MP0003861_abnormal_nervous_system1.14540295
68MP0003879_abnormal_hair_cell1.10773585
69MP0004145_abnormal_muscle_electrophysio1.09494461
70MP0003634_abnormal_glial_cell1.06864003
71MP0002234_abnormal_pharynx_morphology1.05392713
72MP0003631_nervous_system_phenotype1.05249299
73MP0003937_abnormal_limbs/digits/tail_de1.02013124
74MP0002752_abnormal_somatic_nervous1.00957016
75MP0001986_abnormal_taste_sensitivity1.00769850
76MP0010386_abnormal_urinary_bladder0.99922109
77MP0001299_abnormal_eye_distance/0.98151877
78MP0000751_myopathy0.97033029
79MP0000013_abnormal_adipose_tissue0.96124177
80MP0003183_abnormal_peptide_metabolism0.95649946
81MP0002233_abnormal_nose_morphology0.95540107
82MP0001485_abnormal_pinna_reflex0.95024303
83MP0002152_abnormal_brain_morphology0.94211294
84MP0001188_hyperpigmentation0.93741675
85MP0002751_abnormal_autonomic_nervous0.92552364
86MP0001963_abnormal_hearing_physiology0.92112044
87MP0003690_abnormal_glial_cell0.91919873
88MP0003119_abnormal_digestive_system0.91094433
89MP0002938_white_spotting0.90416241
90MP0003938_abnormal_ear_development0.89954620
91MP0003787_abnormal_imprinting0.87756108
92MP0002069_abnormal_eating/drinking_beha0.86742293
93MP0003632_abnormal_nervous_system0.86677059
94MP0003283_abnormal_digestive_organ0.85369635
95MP0006072_abnormal_retinal_apoptosis0.84167587
96MP0000631_abnormal_neuroendocrine_gland0.83745280
97MP0008872_abnormal_physiological_respon0.83523866
98MP0002638_abnormal_pupillary_reflex0.82938315
99MP0005535_abnormal_body_temperature0.82560765
100MP0000647_abnormal_sebaceous_gland0.82333856
101MP0005394_taste/olfaction_phenotype0.81017347
102MP0005499_abnormal_olfactory_system0.81017347
103MP0000604_amyloidosis0.80331076
104MP0004043_abnormal_pH_regulation0.79903310
105MP0004085_abnormal_heartbeat0.79303545
106MP0005195_abnormal_posterior_eye0.79288998
107MP0000049_abnormal_middle_ear0.79274184
108MP0000427_abnormal_hair_cycle0.78641924
109MP0001293_anophthalmia0.77284736
110MP0005379_endocrine/exocrine_gland_phen0.74714799
111MP0000383_abnormal_hair_follicle0.74342534
112MP0002090_abnormal_vision0.73977112
113MP0002697_abnormal_eye_size0.73219994
114MP0005409_darkened_coat_color0.72722695
115MP0002876_abnormal_thyroid_physiology0.72618893
116MP0001177_atelectasis0.72384854
117MP0003755_abnormal_palate_morphology0.71986629
118MP0005253_abnormal_eye_physiology0.71848035
119MP0008874_decreased_physiological_sensi0.70733310
120MP0001664_abnormal_digestion0.69377925
121MP0005171_absent_coat_pigmentation0.67535979
122MP0000026_abnormal_inner_ear0.65549301
123MP0003137_abnormal_impulse_conducting0.60373230
124MP0010234_abnormal_vibrissa_follicle0.60167881
125MP0000747_muscle_weakness0.57424000
126MP0001943_abnormal_respiration0.56792975
127MP0000538_abnormal_urinary_bladder0.53967877
128MP0000579_abnormal_nail_morphology0.51136846
129MP0004215_abnormal_myocardial_fiber0.49798181

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.04243276
2Myokymia (HP:0002411)5.63312385
3Focal seizures (HP:0007359)4.76058959
4Atonic seizures (HP:0010819)4.31377292
5Febrile seizures (HP:0002373)3.87239990
6Action tremor (HP:0002345)3.81761714
7Visual hallucinations (HP:0002367)3.81070710
8Progressive cerebellar ataxia (HP:0002073)3.80656421
9Epileptic encephalopathy (HP:0200134)3.71126380
10Supranuclear gaze palsy (HP:0000605)3.65640803
11Pheochromocytoma (HP:0002666)3.62009832
12Absence seizures (HP:0002121)3.57381399
13Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.39684977
14Dialeptic seizures (HP:0011146)3.34971091
15Insidious onset (HP:0003587)3.30748419
16Termporal pattern (HP:0011008)3.30748419
17Ankle clonus (HP:0011448)3.29086928
18Generalized tonic-clonic seizures (HP:0002069)3.27923573
19Neuroendocrine neoplasm (HP:0100634)3.16128715
20Neurofibrillary tangles (HP:0002185)3.12709879
21Abnormal ciliary motility (HP:0012262)3.10320599
22Abnormal respiratory epithelium morphology (HP:0012253)3.09414632
23Abnormal respiratory motile cilium morphology (HP:0005938)3.09414632
24Abnormal respiratory motile cilium physiology (HP:0012261)3.05202897
25Absent/shortened dynein arms (HP:0200106)3.01953582
26Dynein arm defect of respiratory motile cilia (HP:0012255)3.01953582
27Limb dystonia (HP:0002451)2.97749403
28Abnormality of the corticospinal tract (HP:0002492)2.96539609
29Ulnar claw (HP:0001178)2.94824363
30True hermaphroditism (HP:0010459)2.80237482
31Cerebral inclusion bodies (HP:0100314)2.77665646
32Rhinitis (HP:0012384)2.75100011
33Nephronophthisis (HP:0000090)2.74375768
34Dysmetria (HP:0001310)2.73144981
35Spastic gait (HP:0002064)2.71257539
36Truncal ataxia (HP:0002078)2.69270237
37Pancreatic fibrosis (HP:0100732)2.69215273
38Volvulus (HP:0002580)2.69012313
39Hyperventilation (HP:0002883)2.66148870
40Scanning speech (HP:0002168)2.63192155
41Dysdiadochokinesis (HP:0002075)2.59038547
42Degeneration of the lateral corticospinal tracts (HP:0002314)2.58314007
43Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.58314007
44Medial flaring of the eyebrow (HP:0010747)2.58311287
45Anxiety (HP:0000739)2.56208532
46Amblyopia (HP:0000646)2.49728518
47Impaired vibration sensation in the lower limbs (HP:0002166)2.49711564
48Gaze-evoked nystagmus (HP:0000640)2.47894404
49Hypothermia (HP:0002045)2.44673616
50Molar tooth sign on MRI (HP:0002419)2.43876189
51Abnormality of midbrain morphology (HP:0002418)2.43876189
52Abnormality of the labia minora (HP:0012880)2.43832666
53Broad-based gait (HP:0002136)2.42858536
54Depression (HP:0000716)2.40904173
55Agitation (HP:0000713)2.39578549
56Abnormal eating behavior (HP:0100738)2.37575313
57Urinary bladder sphincter dysfunction (HP:0002839)2.37109076
58Intestinal atresia (HP:0011100)2.34327448
59Pancreatic cysts (HP:0001737)2.33853449
60Peripheral hypomyelination (HP:0007182)2.33327159
61Urinary urgency (HP:0000012)2.32511536
62Epileptiform EEG discharges (HP:0011182)2.29102205
63Drooling (HP:0002307)2.28030833
64Excessive salivation (HP:0003781)2.28030833
65Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.26939015
66EEG with generalized epileptiform discharges (HP:0011198)2.25944236
67Nephrogenic diabetes insipidus (HP:0009806)2.25922700
68Abnormality of the renal medulla (HP:0100957)2.23245552
69Intention tremor (HP:0002080)2.22978543
70Oligodactyly (hands) (HP:0001180)2.21605598
71Hepatoblastoma (HP:0002884)2.19148891
72Chronic hepatic failure (HP:0100626)2.18995131
73Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.16355653
74Hypsarrhythmia (HP:0002521)2.15378026
75Hemiparesis (HP:0001269)2.13562883
76Lower limb muscle weakness (HP:0007340)2.13297599
77Papillary thyroid carcinoma (HP:0002895)2.12844549
78Postural instability (HP:0002172)2.11673955
79Blue irides (HP:0000635)2.10295365
80Progressive inability to walk (HP:0002505)2.10163797
81Failure to thrive in infancy (HP:0001531)2.07764585
82Onion bulb formation (HP:0003383)2.06751461
83Ventricular fibrillation (HP:0001663)2.06235395
84Megalencephaly (HP:0001355)2.05285745
85Specific learning disability (HP:0001328)2.03483935
86Poor coordination (HP:0002370)2.03206826
87Poor eye contact (HP:0000817)2.02923352
88Torticollis (HP:0000473)2.02413863
89Postural tremor (HP:0002174)2.01933434
90Hammertoe (HP:0001765)2.01867991
91Genital tract atresia (HP:0001827)2.01242614
92Abnormal social behavior (HP:0012433)1.99460853
93Impaired social interactions (HP:0000735)1.99460853
94Esophageal atresia (HP:0002032)1.96954243
95Retinal dysplasia (HP:0007973)1.94674728
96Gait imbalance (HP:0002141)1.94644338
97Vaginal atresia (HP:0000148)1.94538702
98Postaxial hand polydactyly (HP:0001162)1.91201669
99Hypoventilation (HP:0002791)1.90177529
100Abnormality of calcium-phosphate metabolism (HP:0100530)1.89861740
101Chronic bronchitis (HP:0004469)1.88829655
102Clonus (HP:0002169)1.88692095
103Polyphagia (HP:0002591)1.88193991
104Steppage gait (HP:0003376)1.87337647
105Gastrointestinal atresia (HP:0002589)1.86194054
106Occipital encephalocele (HP:0002085)1.85731107
107Cortical dysplasia (HP:0002539)1.84959303
108Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.84127366
109Bradykinesia (HP:0002067)1.83018697
110Absent speech (HP:0001344)1.81629735
111Morphological abnormality of the pyramidal tract (HP:0002062)1.81532313
112Akinesia (HP:0002304)1.81510613
113Focal dystonia (HP:0004373)1.81434178
114Oligodactyly (HP:0012165)1.79961074
115Genetic anticipation (HP:0003743)1.79894375
116Fetal akinesia sequence (HP:0001989)1.79039772
117Labial hypoplasia (HP:0000066)1.78985994
118Hypoplasia of the brainstem (HP:0002365)1.78678522
119Aplasia/Hypoplasia of the brainstem (HP:0007362)1.78678522
120Abnormality of pain sensation (HP:0010832)1.78675267
121Impaired pain sensation (HP:0007328)1.78675267
122Generalized myoclonic seizures (HP:0002123)1.77929726
123Narrow forehead (HP:0000341)1.77658646
124Anosmia (HP:0000458)1.77504739
125Psychosis (HP:0000709)1.77164326
126Lissencephaly (HP:0001339)1.76325781
127Postaxial foot polydactyly (HP:0001830)1.75891020
128Cystic liver disease (HP:0006706)1.75867113
129Gait ataxia (HP:0002066)1.75609816
130Aplasia involving bones of the extremities (HP:0009825)1.75522506
131Aplasia involving bones of the upper limbs (HP:0009823)1.75522506
132Aplasia of the phalanges of the hand (HP:0009802)1.75522506
133Sensory axonal neuropathy (HP:0003390)1.75174288
134Renal hypoplasia (HP:0000089)1.75103335
135Aqueductal stenosis (HP:0002410)1.74759884
136Optic nerve hypoplasia (HP:0000609)1.74459586
137Cutaneous finger syndactyly (HP:0010554)1.73077813
138Craniofacial dystonia (HP:0012179)1.71561494
139Decreased motor nerve conduction velocity (HP:0003431)1.71112746
140Protruding tongue (HP:0010808)1.71095476
141Congenital primary aphakia (HP:0007707)1.71014742
142Papilledema (HP:0001085)1.69838991
143Sleep apnea (HP:0010535)1.65224573
144Shawl scrotum (HP:0000049)1.64218784
145Thyroid carcinoma (HP:0002890)1.63558826
146Preaxial hand polydactyly (HP:0001177)1.63214405
147Anophthalmia (HP:0000528)1.62914775
148Split foot (HP:0001839)1.61979584
149Spastic tetraplegia (HP:0002510)1.61412738
150Anencephaly (HP:0002323)1.60192174
151Poor suck (HP:0002033)1.58237978
152Hypoplastic female external genitalia (HP:0012815)1.58018290
153Septo-optic dysplasia (HP:0100842)1.57290974
154Abnormality of salivation (HP:0100755)1.57148235
155Status epilepticus (HP:0002133)1.55672212
156Pachygyria (HP:0001302)1.55639793
157Sclerocornea (HP:0000647)1.55451627

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.08271817
2MAP3K93.31200379
3EPHA42.89490610
4MAP3K42.87186106
5NTRK12.61069525
6MINK12.59009991
7MARK12.48817527
8CASK2.39686625
9MAP2K72.29766806
10PNCK2.04537792
11MAP2K42.00878940
12STK392.00465190
13KSR21.91408811
14PAK61.87010333
15MAP3K121.79731222
16NTRK21.74229235
17TNIK1.66316144
18OXSR11.65775623
19GRK51.61684223
20MAP3K21.60896775
21DAPK21.60628315
22FRK1.60288304
23WNK31.51101340
24UHMK11.50594006
25TRIM281.48908096
26DYRK21.46080462
27MAPK131.43937867
28WNK41.42403407
29LMTK21.41318645
30CDK51.40987221
31ARAF1.33525562
32SGK4941.29147902
33SGK2231.29147902
34MKNK21.28751447
35PRKD31.28197958
36CDK191.27078575
37PHKG11.25601286
38PHKG21.25601286
39KSR11.24306206
40ERBB31.22536799
41WNK11.20914090
42BCR1.13047639
43CAMK2A1.11630066
44PLK21.08196328
45PRKCG1.06879567
46RIPK41.06004444
47RET1.05923092
48CSNK1G21.05922920
49PAK31.02407606
50LATS21.02399373
51CAMK2B0.99215800
52MAP4K20.98874363
53FER0.98871265
54MAPKAPK50.97400380
55NEK10.96743289
56TYRO30.90392103
57CAMK2D0.90273947
58FGFR20.89202160
59CAMKK10.88404126
60LIMK10.82671595
61CDK140.80931064
62CSNK1G30.78662712
63PRKCE0.77423733
64WEE10.76034104
65SGK20.75950873
66CAMKK20.73526292
67STK380.73498689
68INSRR0.73472506
69EPHA30.73230838
70GRK70.73163126
71CDK180.73092932
72MKNK10.72516542
73PINK10.72432638
74FES0.72040930
75CAMK2G0.71875376
76PKN10.70801130
77CDK150.70218621
78SIK20.69645880
79MAP3K10.68555163
80SRPK10.67853502
81STK110.67669219
82STK38L0.67587565
83ROCK20.66864477
84CCNB10.66582106
85PRKCH0.66009030
86PRPF4B0.65987369
87CAMK1G0.64114626
88MAP2K10.63917086
89* CSNK1E0.62780914
90DYRK1A0.60409678
91PTK2B0.60304808
92CDK11A0.60304170
93MAP3K130.59732708
94ADRBK10.59579579
95NEK60.58762291
96ERBB20.57251375
97DAPK10.56361137
98CDC42BPA0.55080364
99SGK10.54684558
100CDK30.54323705
101TNK20.53585469
102MARK20.53057985
103PRKCZ0.52933837
104CAMK10.52659023
105CSNK1A1L0.52620590
106EPHB20.51223305
107BMPR20.49593721
108SGK30.48592655
109PDPK10.48365663
110CSNK1G10.47607734
111NME10.46688558
112FGR0.46554245
113DYRK30.45581533
114PRKACA0.45273106
115CSNK1D0.45216338
116BMPR1B0.45036455
117PRKDC0.44996523
118RPS6KA30.44534742
119MAPK150.44019926
120PLK40.43769311
121CDC70.43721783
122SIK30.43201653
123PRKACB0.42317372
124BRD40.39793244
125TSSK60.39637182
126AKT30.38716147
127FGFR10.38667462
128MAPK100.38509434
129PRKAA10.38340709
130CAMK40.38218137
131PLK30.37260999
132PRKG10.37134297

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.20091137
2Synaptic vesicle cycle_Homo sapiens_hsa047213.13215256
3GABAergic synapse_Homo sapiens_hsa047272.45643654
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.37106795
5Circadian entrainment_Homo sapiens_hsa047132.23271929
6Glutamatergic synapse_Homo sapiens_hsa047242.20053458
7Olfactory transduction_Homo sapiens_hsa047402.17703819
8Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.14367794
9Amphetamine addiction_Homo sapiens_hsa050312.11314276
10Insulin secretion_Homo sapiens_hsa049112.05442679
11Morphine addiction_Homo sapiens_hsa050322.04739721
12Long-term potentiation_Homo sapiens_hsa047202.04085534
13Dopaminergic synapse_Homo sapiens_hsa047282.02261893
14Taste transduction_Homo sapiens_hsa047421.94971467
15Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.87289133
16Salivary secretion_Homo sapiens_hsa049701.84023014
17Serotonergic synapse_Homo sapiens_hsa047261.83855251
18Collecting duct acid secretion_Homo sapiens_hsa049661.80153673
19Cocaine addiction_Homo sapiens_hsa050301.71462826
20Cholinergic synapse_Homo sapiens_hsa047251.67439998
21Long-term depression_Homo sapiens_hsa047301.58240746
22Gastric acid secretion_Homo sapiens_hsa049711.55916215
23Renin secretion_Homo sapiens_hsa049241.51312859
24Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.42402483
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.40944775
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.40794142
27Phototransduction_Homo sapiens_hsa047441.32528899
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.30243238
29Calcium signaling pathway_Homo sapiens_hsa040201.28137488
30Vibrio cholerae infection_Homo sapiens_hsa051101.26973276
31Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26904279
32Axon guidance_Homo sapiens_hsa043601.24980595
33Oxytocin signaling pathway_Homo sapiens_hsa049211.22378206
34Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.21733259
35Cardiac muscle contraction_Homo sapiens_hsa042601.19455076
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19326330
37GnRH signaling pathway_Homo sapiens_hsa049121.18352174
38Gap junction_Homo sapiens_hsa045401.17284462
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13957699
40Oxidative phosphorylation_Homo sapiens_hsa001901.13475183
41Dorso-ventral axis formation_Homo sapiens_hsa043201.13365556
42Nitrogen metabolism_Homo sapiens_hsa009101.11724052
43Protein export_Homo sapiens_hsa030601.10868535
44Propanoate metabolism_Homo sapiens_hsa006401.09772166
45Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.07623236
46Type II diabetes mellitus_Homo sapiens_hsa049301.01479986
47Melanogenesis_Homo sapiens_hsa049160.99773820
48cAMP signaling pathway_Homo sapiens_hsa040240.99115926
49Pancreatic secretion_Homo sapiens_hsa049720.98603564
50Phosphatidylinositol signaling system_Homo sapiens_hsa040700.95995701
51Alzheimers disease_Homo sapiens_hsa050100.94700409
52Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.94384015
53Estrogen signaling pathway_Homo sapiens_hsa049150.94077774
54Butanoate metabolism_Homo sapiens_hsa006500.92504082
55Hippo signaling pathway_Homo sapiens_hsa043900.91465425
56Basal cell carcinoma_Homo sapiens_hsa052170.86160207
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.86133635
58Vitamin B6 metabolism_Homo sapiens_hsa007500.85357631
59ErbB signaling pathway_Homo sapiens_hsa040120.84357173
60Parkinsons disease_Homo sapiens_hsa050120.81203492
61Thyroid hormone synthesis_Homo sapiens_hsa049180.78834165
62beta-Alanine metabolism_Homo sapiens_hsa004100.78169581
63cGMP-PKG signaling pathway_Homo sapiens_hsa040220.76577663
64Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.75743293
65Bile secretion_Homo sapiens_hsa049760.74529419
66Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.70969398
67Fatty acid elongation_Homo sapiens_hsa000620.70922546
68Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69890618
69Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.69398151
70Tight junction_Homo sapiens_hsa045300.69192258
71Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.67809958
72Histidine metabolism_Homo sapiens_hsa003400.67723341
73Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67471150
74Glioma_Homo sapiens_hsa052140.66942652
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.64301470
76Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.61761021
77Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.58560146
78Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58520752
79Choline metabolism in cancer_Homo sapiens_hsa052310.58046397
80Primary bile acid biosynthesis_Homo sapiens_hsa001200.57703375
81Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57155814
82Fatty acid metabolism_Homo sapiens_hsa012120.56716310
83Fatty acid biosynthesis_Homo sapiens_hsa000610.56393808
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56172813
85Basal transcription factors_Homo sapiens_hsa030220.55399777
86Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54976861
87Ether lipid metabolism_Homo sapiens_hsa005650.54424082
88Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53887026
89Glucagon signaling pathway_Homo sapiens_hsa049220.53519460
90Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52797750
91Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51701192
92Regulation of autophagy_Homo sapiens_hsa041400.51613736
93Prion diseases_Homo sapiens_hsa050200.50972645
94Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50848299
95mRNA surveillance pathway_Homo sapiens_hsa030150.50778495
96ABC transporters_Homo sapiens_hsa020100.49835310
97Steroid biosynthesis_Homo sapiens_hsa001000.49129966
98Oocyte meiosis_Homo sapiens_hsa041140.47419612
99Ras signaling pathway_Homo sapiens_hsa040140.47414305
100SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47224936
101Hedgehog signaling pathway_Homo sapiens_hsa043400.47184058
102MAPK signaling pathway_Homo sapiens_hsa040100.47024725
103Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.46826330
104Circadian rhythm_Homo sapiens_hsa047100.46380058
105Dilated cardiomyopathy_Homo sapiens_hsa054140.46241251
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.45664763
107Linoleic acid metabolism_Homo sapiens_hsa005910.45558420
108Arginine biosynthesis_Homo sapiens_hsa002200.44185756
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.43297961
110Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42317103
111Inositol phosphate metabolism_Homo sapiens_hsa005620.42026449
112Sulfur metabolism_Homo sapiens_hsa009200.41999560
113Huntingtons disease_Homo sapiens_hsa050160.41962349
114Ovarian steroidogenesis_Homo sapiens_hsa049130.41565155
115Tyrosine metabolism_Homo sapiens_hsa003500.41405086
116Chemical carcinogenesis_Homo sapiens_hsa052040.40106210
117Selenocompound metabolism_Homo sapiens_hsa004500.39809809
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39799439
119Arginine and proline metabolism_Homo sapiens_hsa003300.39763245
120Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.39652585
121Alcoholism_Homo sapiens_hsa050340.38486668
122Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38457435
123Wnt signaling pathway_Homo sapiens_hsa043100.35910302
124Phenylalanine metabolism_Homo sapiens_hsa003600.35660487
125Maturity onset diabetes of the young_Homo sapiens_hsa049500.35600756
126Insulin signaling pathway_Homo sapiens_hsa049100.34645865
127Neurotrophin signaling pathway_Homo sapiens_hsa047220.31299196
128Endocytosis_Homo sapiens_hsa041440.31230558
129VEGF signaling pathway_Homo sapiens_hsa043700.30833001
130Mineral absorption_Homo sapiens_hsa049780.30781772

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