KIF26A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)4.56247384
2planar cell polarity pathway involved in neural tube closure (GO:0090179)4.45331420
3cardiac myofibril assembly (GO:0055003)4.43296709
4heterochromatin organization (GO:0070828)4.28445829
5regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.14737481
6dichotomous subdivision of an epithelial terminal unit (GO:0060600)4.00047788
7regulation of gene silencing by RNA (GO:0060966)3.94654171
8regulation of posttranscriptional gene silencing (GO:0060147)3.94654171
9regulation of gene silencing by miRNA (GO:0060964)3.94654171
10lateral sprouting from an epithelium (GO:0060601)3.94518145
11bundle of His cell to Purkinje myocyte communication (GO:0086069)3.91982624
12coronary vasculature morphogenesis (GO:0060977)3.91860562
13plasma membrane repair (GO:0001778)3.90637909
14protein complex localization (GO:0031503)3.87618679
15nucleosome disassembly (GO:0006337)3.86335368
16protein-DNA complex disassembly (GO:0032986)3.86335368
17cell migration in hindbrain (GO:0021535)3.83000842
18hemidesmosome assembly (GO:0031581)3.81439067
19polarized epithelial cell differentiation (GO:0030859)3.78369297
20lymph vessel development (GO:0001945)3.75694259
21nuclear pore complex assembly (GO:0051292)3.72626618
22sarcomere organization (GO:0045214)3.67947104
23regulation of cardioblast differentiation (GO:0051890)3.64040962
24convergent extension (GO:0060026)3.61824726
25myofibril assembly (GO:0030239)3.47237647
26histone arginine methylation (GO:0034969)3.46080883
27heart trabecula formation (GO:0060347)3.45002897
28* enteric nervous system development (GO:0048484)3.44043621
29mitotic chromosome condensation (GO:0007076)3.44005904
30negative regulation of potassium ion transmembrane transporter activity (GO:1901017)3.38752941
31heart morphogenesis (GO:0003007)3.38729933
32cell migration involved in heart development (GO:0060973)3.35682745
33vascular endothelial growth factor signaling pathway (GO:0038084)3.35304130
34regulation of cardioblast proliferation (GO:0003264)3.33815150
35regulation of secondary heart field cardioblast proliferation (GO:0003266)3.33815150
36negative regulation of potassium ion transmembrane transport (GO:1901380)3.32480360
37peptidyl-arginine omega-N-methylation (GO:0035247)3.30801546
38hippo signaling (GO:0035329)3.30602823
39anatomical structure regression (GO:0060033)3.29579786
40embryonic foregut morphogenesis (GO:0048617)3.26279397
41protein heterotrimerization (GO:0070208)3.22884048
42nuclear pore organization (GO:0006999)3.21267757
43lymphangiogenesis (GO:0001946)3.20551464
44paraxial mesoderm development (GO:0048339)3.19958763
45positive regulation of cell cycle G2/M phase transition (GO:1902751)3.18828193
46positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)3.18828193
47basement membrane organization (GO:0071711)3.16524999
48positive regulation of transcription regulatory region DNA binding (GO:2000679)3.14861826
49neuron projection extension involved in neuron projection guidance (GO:1902284)3.13418737
50axon extension involved in axon guidance (GO:0048846)3.13418737
51establishment of apical/basal cell polarity (GO:0035089)3.12824516
52establishment of planar polarity (GO:0001736)3.11820736
53establishment of tissue polarity (GO:0007164)3.11820736
54DNA replication initiation (GO:0006270)3.10089356
55negative regulation of catenin import into nucleus (GO:0035414)3.10072167
56semaphorin-plexin signaling pathway (GO:0071526)3.09810643
57chromatin assembly (GO:0031497)3.08341673
58cellular protein complex localization (GO:0034629)3.08103266
59cellular response to vascular endothelial growth factor stimulus (GO:0035924)3.07300047
60cardiac muscle cell development (GO:0055013)3.05579274
61cardiac ventricle formation (GO:0003211)3.05442600
62cardiac chamber formation (GO:0003207)3.05348960
63L-serine metabolic process (GO:0006563)3.03594634
64layer formation in cerebral cortex (GO:0021819)3.03465286
65trabecula formation (GO:0060343)3.02141757
66adult heart development (GO:0007512)3.01943605
67cardiac cell development (GO:0055006)3.01066284
68ventricular cardiac muscle cell action potential (GO:0086005)3.00114620
69notochord development (GO:0030903)2.97966026
70proximal/distal pattern formation (GO:0009954)2.96787696
71molting cycle (GO:0042303)2.94502175
72hair cycle (GO:0042633)2.94502175
73DNA strand elongation involved in DNA replication (GO:0006271)2.94246402
74regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.94005905
75regulation of mammary gland epithelial cell proliferation (GO:0033599)2.93964448
76non-canonical Wnt signaling pathway (GO:0035567)2.93766634
77embryonic heart tube development (GO:0035050)2.93537315
78protein localization to chromosome, centromeric region (GO:0071459)2.91493314
79adherens junction assembly (GO:0034333)2.91361678
80apoptotic process involved in morphogenesis (GO:0060561)2.90519401
81negative regulation of histone methylation (GO:0031061)2.89242623
82positive regulation of SMAD protein import into nucleus (GO:0060391)2.87894024
83Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.87444687
84negative regulation of cell fate specification (GO:0009996)2.86832635
85establishment of integrated proviral latency (GO:0075713)2.86824343
86cell migration involved in sprouting angiogenesis (GO:0002042)2.86095503
87DNA strand elongation (GO:0022616)2.85859566
88morphogenesis of an endothelium (GO:0003159)2.85357431
89endothelial tube morphogenesis (GO:0061154)2.85357431
90mesenchymal cell proliferation (GO:0010463)2.85145773
91establishment of monopolar cell polarity (GO:0061162)2.84651360
92establishment or maintenance of monopolar cell polarity (GO:0061339)2.84651360
93protein localization to kinetochore (GO:0034501)2.84089457
94regulation of hippo signaling (GO:0035330)2.83511704
95cell-substrate junction assembly (GO:0007044)2.81860497
96negative regulation of striated muscle cell apoptotic process (GO:0010664)2.81828149
97regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.80575387
98establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.80266319
99regulation of heart morphogenesis (GO:2000826)2.79699736
100peptidyl-arginine N-methylation (GO:0035246)2.78041606
101peptidyl-arginine methylation (GO:0018216)2.78041606
102cardiac muscle cell proliferation (GO:0060038)2.77625571
103renal system development (GO:0072001)2.77576849
104cytoskeletal anchoring at plasma membrane (GO:0007016)2.77257143
105regulation of translational fidelity (GO:0006450)2.76945063
106neural tube development (GO:0021915)2.76672072
107lung-associated mesenchyme development (GO:0060484)2.76027257
108regulation of establishment of planar polarity (GO:0090175)2.75686931
109regulation of transcription from RNA polymerase II promoter involved in heart development (GO:1901212.75643883
110cell surface receptor signaling pathway involved in heart development (GO:0061311)2.75273353
111vasculogenesis (GO:0001570)2.74801822
112negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.74643440
113head development (GO:0060322)2.74360419
114peripheral nervous system neuron development (GO:0048935)2.74198577
115ventricular cardiac muscle tissue morphogenesis (GO:0055010)2.73205875
116negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.72991919
117negative regulation of axon extension involved in axon guidance (GO:0048843)2.72159007
118sympathetic nervous system development (GO:0048485)2.71347853
119bone trabecula formation (GO:0060346)2.70819911
120endothelial cell differentiation (GO:0045446)2.70806436
121mRNA stabilization (GO:0048255)2.70523008
122RNA stabilization (GO:0043489)2.70523008
123ectodermal placode formation (GO:0060788)2.70504609
124actomyosin structure organization (GO:0031032)2.70086239
125regulation of axon extension involved in axon guidance (GO:0048841)2.69571363
126mitotic sister chromatid cohesion (GO:0007064)2.69116088
127retina vasculature morphogenesis in camera-type eye (GO:0061299)2.68896808
128negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.68880342
129patterning of blood vessels (GO:0001569)2.68459906
130branching involved in salivary gland morphogenesis (GO:0060445)2.68161053
131gastrulation with mouth forming second (GO:0001702)2.68101392
132regulation of NFAT protein import into nucleus (GO:0051532)2.66664420
133pre-miRNA processing (GO:0031054)2.66378306
134regulation of RNA export from nucleus (GO:0046831)2.66322601
135DNA duplex unwinding (GO:0032508)2.66212626
136apoptotic process involved in development (GO:1902742)2.65695811
137regulation of cell fate specification (GO:0042659)2.64140970
138mitotic sister chromatid segregation (GO:0000070)2.64126462
139blood vessel endothelial cell migration (GO:0043534)2.63961261
140regulation of stem cell maintenance (GO:2000036)2.63501716
141regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.62150921
142cardiac muscle contraction (GO:0060048)2.61983336
143mesenchyme morphogenesis (GO:0072132)2.61667892
144regulation of histone H3-K9 methylation (GO:0051570)2.61148000
145atrial septum morphogenesis (GO:0060413)2.60190244
146establishment or maintenance of bipolar cell polarity (GO:0061245)2.59795921
147establishment or maintenance of apical/basal cell polarity (GO:0035088)2.59795921
148outflow tract septum morphogenesis (GO:0003148)2.59579805
149outer ear morphogenesis (GO:0042473)2.58768604
150atrioventricular valve morphogenesis (GO:0003181)2.57705612
151ganglion development (GO:0061548)2.57575894
152desmosome organization (GO:0002934)2.56586577
153cell communication involved in cardiac conduction (GO:0086065)2.55572423
154pore complex assembly (GO:0046931)2.54787568
155endocardial cushion morphogenesis (GO:0003203)2.54391718
156cardiac muscle tissue morphogenesis (GO:0055008)2.53947135
157blood vessel maturation (GO:0001955)2.53212849
158glial cell proliferation (GO:0014009)2.53191097
159sister chromatid segregation (GO:0000819)2.52459357
160regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.52249741
161odontogenesis of dentin-containing tooth (GO:0042475)2.52140917
162chromatin silencing (GO:0006342)2.51632942
163DNA geometric change (GO:0032392)2.49948576
164regulation of chromatin binding (GO:0035561)2.47064262
165G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.46704026
166peptidyl-lysine dimethylation (GO:0018027)2.41256990
167L-alpha-amino acid transmembrane transport (GO:1902475)2.40601800
168DNA topological change (GO:0006265)2.40363406
169embryonic body morphogenesis (GO:0010172)2.39022146
170intracellular estrogen receptor signaling pathway (GO:0030520)2.36719260
171negative regulation of DNA repair (GO:0045738)2.36050910
172regulation of catenin import into nucleus (GO:0035412)2.36003897
173body morphogenesis (GO:0010171)2.34835160
174chromatin assembly or disassembly (GO:0006333)2.34724967

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.97552872
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.63674162
3STAT6_21828071_ChIP-Seq_BEAS2B_Human4.10430416
4ZNF263_19887448_ChIP-Seq_K562_Human2.83406007
5EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.78372165
6MYC_18555785_ChIP-Seq_MESCs_Mouse2.75218025
7ZFP281_18757296_ChIP-ChIP_E14_Mouse2.57900185
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.57486680
9ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.35808964
10SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.27910035
11KDM2B_26808549_Chip-Seq_SUP-B15_Human2.27164611
12* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.25599675
13WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse2.22725831
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.22341269
15KDM2B_26808549_Chip-Seq_K562_Human2.18574823
16ZFP281_27345836_Chip-Seq_ESCs_Mouse2.12355641
17PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.11444859
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.02833348
19CLOCK_20551151_ChIP-Seq_293T_Human2.02802819
20RNF2_18974828_ChIP-Seq_MESCs_Mouse1.98619042
21EZH2_18974828_ChIP-Seq_MESCs_Mouse1.98619042
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.95794478
23KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.95110040
24KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.95110040
25KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.95110040
26KDM2B_26808549_Chip-Seq_DND41_Human1.94108278
27* EZH2_27304074_Chip-Seq_ESCs_Mouse1.91457144
28TRIM28_21343339_ChIP-Seq_HEK293_Human1.90171729
29NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.87972092
30* ELK3_25401928_ChIP-Seq_HUVEC_Human1.84866399
31* ISL1_27105846_Chip-Seq_CPCs_Mouse1.82662461
32CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.82223426
33E2F4_17652178_ChIP-ChIP_JURKAT_Human1.80840317
34MYC_19030024_ChIP-ChIP_MESCs_Mouse1.77789094
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.74054354
36TP53_20018659_ChIP-ChIP_R1E_Mouse1.73739630
37TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.73156989
38EP300_21415370_ChIP-Seq_HL-1_Mouse1.73113803
39XRN2_22483619_ChIP-Seq_HELA_Human1.69533801
40ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.67549612
41DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.67229670
42* RING1B_27294783_Chip-Seq_NPCs_Mouse1.66597740
43* KDM2B_26808549_Chip-Seq_JURKAT_Human1.63155631
44HIF1A_21447827_ChIP-Seq_MCF-7_Human1.63124860
45* RNF2_27304074_Chip-Seq_ESCs_Mouse1.61902266
46MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.60539337
47MYC_18358816_ChIP-ChIP_MESCs_Mouse1.60206138
48* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.59179558
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.58346138
50TBX20_22328084_ChIP-Seq_HEART_Mouse1.58200406
51TBX20_22080862_ChIP-Seq_HEART_Mouse1.58200406
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.57817981
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.56609678
54THAP11_20581084_ChIP-Seq_MESCs_Mouse1.56497244
55KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.54241164
56EED_16625203_ChIP-ChIP_MESCs_Mouse1.52532005
57* RING1B_27294783_Chip-Seq_ESCs_Mouse1.51894498
58* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.50329641
59ESR1_15608294_ChIP-ChIP_MCF-7_Human1.49524525
60ESR2_21235772_ChIP-Seq_MCF-7_Human1.49140942
61LXR_22292898_ChIP-Seq_THP-1_Human1.47568234
62SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.46070124
63* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.45586929
64SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.45578976
65TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.44806458
66E2F1_21310950_ChIP-Seq_MCF-7_Human1.44462614
67KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.42633256
68ZFX_18555785_ChIP-Seq_MESCs_Mouse1.42109665
69* ERG_21242973_ChIP-ChIP_JURKAT_Human1.41558090
70PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.41536833
71SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.41332374
72SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.40442345
73RACK7_27058665_Chip-Seq_MCF-7_Human1.38853301
74CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.38314571
75* EZH2_27294783_Chip-Seq_ESCs_Mouse1.38303649
76NANOG_21062744_ChIP-ChIP_HESCs_Human1.37755479
77SOX2_16153702_ChIP-ChIP_HESCs_Human1.37580270
78RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.37400053
79EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.37253197
80NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.36962222
81HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.36762667
82P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35848221
83KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.34227101
84KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.34116204
85DROSHA_22980978_ChIP-Seq_HELA_Human1.33513103
86MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.32952704
87* CTCF_27219007_Chip-Seq_Bcells_Human1.30809910
88TP63_19390658_ChIP-ChIP_HaCaT_Human1.30340397
89NANOG_18555785_ChIP-Seq_MESCs_Mouse1.30054087
90KLF4_18555785_ChIP-Seq_MESCs_Mouse1.29736660
91RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.29521926
92* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28661932
93POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.28004944
94NELFA_20434984_ChIP-Seq_ESCs_Mouse1.27986879
95TCF7_22412390_ChIP-Seq_EML_Mouse1.27564477
96CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.26315539
97MYCN_18555785_ChIP-Seq_MESCs_Mouse1.26228878
98WT1_25993318_ChIP-Seq_PODOCYTE_Human1.25090497
99CREB1_26743006_Chip-Seq_LNCaP_Human1.24646933
100ESR1_20079471_ChIP-ChIP_T-47D_Human1.24066201
101TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.24040669
102CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.23554878
103DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.23349054
104POU5F1_16518401_ChIP-PET_MESCs_Mouse1.22954219
105NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.21138811
106TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.20813081
107* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.20478478
108SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.20457741
109EZH2_22144423_ChIP-Seq_EOC_Human1.19903983
110NFIB_24661679_ChIP-Seq_LUNG_Mouse1.19167930
111GATA1_26923725_Chip-Seq_HPCs_Mouse1.17881196
112CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.17210921
113FOXM1_23109430_ChIP-Seq_U2OS_Human1.16758560
114SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.16383172
115SOX9_24532713_ChIP-Seq_HFSC_Mouse1.16280260
116ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.14453493
117FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.14109651
118STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.12657104
119TTF2_22483619_ChIP-Seq_HELA_Human1.11557076
120MYC_22102868_ChIP-Seq_BL_Human1.11267061
121RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.11104767
122* P68_20966046_ChIP-Seq_HELA_Human1.10492635
123* RUNX1_27514584_Chip-Seq_MCF-7_Human1.10443484
124* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.09991096
125DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.09627796
126TET1_21451524_ChIP-Seq_MESCs_Mouse1.09415273
127VDR_21846776_ChIP-Seq_THP-1_Human1.09264699
128* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.08903094
129TCF3_18692474_ChIP-Seq_MESCs_Mouse1.07702702
130AR_21909140_ChIP-Seq_LNCAP_Human1.07502840
131TCF3_18692474_ChIP-Seq_MEFs_Mouse1.07023056
132SOX2_18555785_ChIP-Seq_MESCs_Mouse1.06792600
133NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.06674206
134OCT4_18692474_ChIP-Seq_MEFs_Mouse1.05790923
135MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.05589167
136SRY_22984422_ChIP-ChIP_TESTIS_Rat1.05575558
137SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.05102704
138CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.04704857
139TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.04149796
140KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.03977255
141TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03250454
142NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.02866537
143SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.02641457
144SMC4_20622854_ChIP-Seq_HELA_Human1.02614802
145* SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.02022771
146WT1_19549856_ChIP-ChIP_CCG9911_Human1.00266420
147TP53_22127205_ChIP-Seq_IMR90_Human0.99952069
148KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.99907557
149DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98738743
150SALL1_21062744_ChIP-ChIP_HESCs_Human0.97113057
151NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.97047764

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004084_abnormal_cardiac_muscle3.43371257
2MP0003705_abnormal_hypodermis_morpholog3.38989602
3MP0004272_abnormal_basement_membrane3.37563195
4MP0000751_myopathy3.04427659
5MP0010368_abnormal_lymphatic_system2.92484595
6MP0000537_abnormal_urethra_morphology2.51191857
7MP0002837_dystrophic_cardiac_calcinosis2.37552502
8MP0003111_abnormal_nucleus_morphology2.34983564
9MP0002822_catalepsy2.33441313
10MP0003693_abnormal_embryo_hatching2.30103442
11MP0004215_abnormal_myocardial_fiber2.20247599
12MP0001879_abnormal_lymphatic_vessel2.18107262
13MP0006138_congestive_heart_failure2.12670744
14MP0004957_abnormal_blastocyst_morpholog2.08830818
15MP0002697_abnormal_eye_size2.06161227
16MP0003122_maternal_imprinting1.99887561
17MP0002009_preneoplasia1.98479897
18MP0005623_abnormal_meninges_morphology1.97591233
19MP0009672_abnormal_birth_weight1.97245837
20MP0003567_abnormal_fetal_cardiomyocyte1.95837208
21MP0003646_muscle_fatigue1.95379698
22MP0004036_abnormal_muscle_relaxation1.94311160
23MP0002653_abnormal_ependyma_morphology1.94280923
24MP0005167_abnormal_blood-brain_barrier1.90988816
25MP0002234_abnormal_pharynx_morphology1.88027790
26MP0009053_abnormal_anal_canal1.85509123
27MP0010030_abnormal_orbit_morphology1.84840699
28MP0001730_embryonic_growth_arrest1.84545478
29MP0005330_cardiomyopathy1.82738697
30MP0003385_abnormal_body_wall1.82187246
31MP0008932_abnormal_embryonic_tissue1.78110429
32MP0005187_abnormal_penis_morphology1.76838675
33MP0003077_abnormal_cell_cycle1.75129999
34MP0008438_abnormal_cutaneous_collagen1.73921508
35MP0010630_abnormal_cardiac_muscle1.70850889
36MP0010094_abnormal_chromosome_stability1.70656109
37MP0005275_abnormal_skin_tensile1.69233527
38MP0003123_paternal_imprinting1.67978143
39MP0000579_abnormal_nail_morphology1.65251998
40MP0003890_abnormal_embryonic-extraembry1.60805838
41MP0004087_abnormal_muscle_fiber1.60129575
42MP0000750_abnormal_muscle_regeneration1.59340621
43MP0001544_abnormal_cardiovascular_syste1.57001475
44MP0005385_cardiovascular_system_phenoty1.57001475
45MP0000049_abnormal_middle_ear1.56788615
46MP0008775_abnormal_heart_ventricle1.56163033
47MP0002972_abnormal_cardiac_muscle1.55958896
48MP0002127_abnormal_cardiovascular_syste1.52769669
49MP0003119_abnormal_digestive_system1.51008691
50MP0003137_abnormal_impulse_conducting1.49948075
51MP0006054_spinal_hemorrhage1.44686297
52MP0000566_synostosis1.42240254
53MP0003935_abnormal_craniofacial_develop1.41604505
54* MP0002751_abnormal_autonomic_nervous1.39973910
55MP0000383_abnormal_hair_follicle1.38662541
56MP0001293_anophthalmia1.37722934
57MP0005076_abnormal_cell_differentiation1.37470521
58MP0003878_abnormal_ear_physiology1.37091837
59MP0005377_hearing/vestibular/ear_phenot1.37091837
60MP0000428_abnormal_craniofacial_morphol1.35562481
61MP0000733_abnormal_muscle_development1.34407716
62MP0005620_abnormal_muscle_contractility1.31181707
63MP0004233_abnormal_muscle_weight1.30714718
64MP0001849_ear_inflammation1.29574885
65MP0002092_abnormal_eye_morphology1.28762121
66MP0002106_abnormal_muscle_physiology1.26763723
67MP0002080_prenatal_lethality1.26634843
68MP0003828_pulmonary_edema1.26069784
69MP0006292_abnormal_olfactory_placode1.25929546
70MP0008057_abnormal_DNA_replication1.24698775
71MP0003279_aneurysm1.23754317
72MP0000534_abnormal_ureter_morphology1.23582369
73MP0004085_abnormal_heartbeat1.23463618
74MP0003121_genomic_imprinting1.22973564
75MP0001697_abnormal_embryo_size1.22480494
76MP0002249_abnormal_larynx_morphology1.22391091
77MP0003115_abnormal_respiratory_system1.22316746
78MP0004858_abnormal_nervous_system1.21373073
79MP0002925_abnormal_cardiovascular_devel1.20931116
80MP0000762_abnormal_tongue_morphology1.20474108
81MP0000350_abnormal_cell_proliferation1.20223924
82MP0010678_abnormal_skin_adnexa1.20053897
83MP0004484_altered_response_of1.19074459
84MP0005409_darkened_coat_color1.19021793
85MP0002638_abnormal_pupillary_reflex1.18537522
86MP0004145_abnormal_muscle_electrophysio1.18058022
87MP0003942_abnormal_urinary_system1.17517746
88MP0001188_hyperpigmentation1.17342882
89MP0000778_abnormal_nervous_system1.17147757
90MP0010234_abnormal_vibrissa_follicle1.16955325
91MP0002254_reproductive_system_inflammat1.16041250
92MP0003566_abnormal_cell_adhesion1.15959303
93MP0001299_abnormal_eye_distance/1.14472577
94MP0003755_abnormal_palate_morphology1.13295666
95MP0004133_heterotaxia1.12976081
96MP0000266_abnormal_heart_morphology1.12256871
97MP0003937_abnormal_limbs/digits/tail_de1.11236107
98MP0001286_abnormal_eye_development1.09873080
99MP0002098_abnormal_vibrissa_morphology1.09099345
100MP0002111_abnormal_tail_morphology1.08252374
101MP0002086_abnormal_extraembryonic_tissu1.07389313
102MP0000759_abnormal_skeletal_muscle1.06763749
103MP0001346_abnormal_lacrimal_gland1.06640243
104MP0009703_decreased_birth_body1.05909463
105MP0005369_muscle_phenotype1.04922523
106MP0004197_abnormal_fetal_growth/weight/1.04276449
107MP0002282_abnormal_trachea_morphology1.03993209
108MP0000467_abnormal_esophagus_morphology1.02730164
109MP0000749_muscle_degeneration1.02660074
110MP0000767_abnormal_smooth_muscle1.01949277
111MP0004185_abnormal_adipocyte_glucose1.01859677
112MP0003941_abnormal_skin_development1.01743853
113MP0004130_abnormal_muscle_cell0.99484748
114MP0002088_abnormal_embryonic_growth/wei0.98796794
115MP0005248_abnormal_Harderian_gland0.98577210
116MP0003984_embryonic_growth_retardation0.97783827
117MP0000462_abnormal_digestive_system0.97741291
118MP0005367_renal/urinary_system_phenotyp0.97696726
119MP0000516_abnormal_urinary_system0.97696726
120MP0005666_abnormal_adipose_tissue0.97532411
121MP0002116_abnormal_craniofacial_bone0.97176324
122MP0002128_abnormal_blood_circulation0.96247536
123MP0002081_perinatal_lethality0.95927157
124MP0002084_abnormal_developmental_patter0.95909998
125MP0000003_abnormal_adipose_tissue0.95631299
126MP0000432_abnormal_head_morphology0.95367626
127MP0001672_abnormal_embryogenesis/_devel0.92895378
128MP0005380_embryogenesis_phenotype0.92895378
129MP0002085_abnormal_embryonic_tissue0.92835989
130MP0005375_adipose_tissue_phenotype0.92602660
131MP0002184_abnormal_innervation0.91623933
132MP0010307_abnormal_tumor_latency0.91456842
133MP0009379_abnormal_foot_pigmentation0.91398432
134MP0002932_abnormal_joint_morphology0.91285960
135MP0009250_abnormal_appendicular_skeleto0.90363093
136MP0002896_abnormal_bone_mineralization0.89624121
137MP0009278_abnormal_bone_marrow0.89368049
138* MP0003861_abnormal_nervous_system0.89277176
139MP0001958_emphysema0.88058861
140MP0005670_abnormal_white_adipose0.87892949
141MP0002114_abnormal_axial_skeleton0.86962611
142MP0002233_abnormal_nose_morphology0.86707400
143MP0000955_abnormal_spinal_cord0.86624782
144MP0010352_gastrointestinal_tract_polyps0.84630700
145MP0001348_abnormal_lacrimal_gland0.83169310
146MP0005501_abnormal_skin_physiology0.83141896
147MP0004147_increased_porphyrin_level0.83125993
148MP0002108_abnormal_muscle_morphology0.81125294
149MP0002152_abnormal_brain_morphology0.80260622
150MP0008058_abnormal_DNA_repair0.79718265
151MP0003283_abnormal_digestive_organ0.79221533

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)5.32118520
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)5.32118520
3Abnormality of the 4th metacarpal (HP:0010012)4.56041728
4Sudden death (HP:0001699)3.93607205
5Milia (HP:0001056)3.86240693
6Increased connective tissue (HP:0009025)3.62507357
7Turricephaly (HP:0000262)3.54718319
8Ventricular tachycardia (HP:0004756)3.35132789
9Shallow orbits (HP:0000586)3.29838321
10Neoplasm of the heart (HP:0100544)3.19089067
11Hyperacusis (HP:0010780)3.18741869
12Lymphangioma (HP:0100764)3.17220948
13Muscle fiber splitting (HP:0003555)3.12657030
14Atrophic scars (HP:0001075)3.10619995
15Renal duplication (HP:0000075)3.00799217
16Bladder diverticulum (HP:0000015)2.94862916
17Right ventricular cardiomyopathy (HP:0011663)2.94225222
18Cerebral aneurysm (HP:0004944)2.90198710
19Renovascular hypertension (HP:0100817)2.82425893
20Short phalanx of the thumb (HP:0009660)2.79567073
21High anterior hairline (HP:0009890)2.78732740
22Overriding aorta (HP:0002623)2.78687729
23Abnormality of the parietal bone (HP:0002696)2.77166150
24Elfin facies (HP:0004428)2.76671511
25Broad metatarsal (HP:0001783)2.74289854
26Supernumerary ribs (HP:0005815)2.73025373
27Down-sloping shoulders (HP:0200021)2.70959270
28Hyporeflexia of lower limbs (HP:0002600)2.65010525
29Partial duplication of the phalanx of hand (HP:0009999)2.61594784
30Asymmetry of the thorax (HP:0001555)2.60652129
31Ankle contracture (HP:0006466)2.60310125
32Protrusio acetabuli (HP:0003179)2.58634488
33Abnormality of the phalanges of the hallux (HP:0010057)2.57679556
34Atrial fibrillation (HP:0005110)2.57392143
35Increased variability in muscle fiber diameter (HP:0003557)2.57362546
36Fragile skin (HP:0001030)2.56031499
37Difficulty running (HP:0009046)2.55603171
38Supraventricular arrhythmia (HP:0005115)2.50983862
39Hepatoblastoma (HP:0002884)2.48487399
40Primary atrial arrhythmia (HP:0001692)2.45382114
41Type 1 muscle fiber predominance (HP:0003803)2.44884927
42Flat cornea (HP:0007720)2.36664501
43Midline defect of the nose (HP:0004122)2.36025402
44Supernumerary bones of the axial skeleton (HP:0009144)2.35744304
45Supraventricular tachycardia (HP:0004755)2.34630494
46Abnormality of the calcaneus (HP:0008364)2.33879013
47Skull defect (HP:0001362)2.32968462
48Abnormality of the diencephalon (HP:0010662)2.32040119
49Neonatal hypoglycemia (HP:0001998)2.31367187
50Calcaneovalgus deformity (HP:0001848)2.28492313
51Woolly hair (HP:0002224)2.27919123
52Choanal stenosis (HP:0000452)2.26853474
53Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658)2.25887680
54Cutaneous syndactyly (HP:0012725)2.25859193
55Fragile nails (HP:0001808)2.23148233
56Increased nuchal translucency (HP:0010880)2.21560586
57Chromosomal breakage induced by crosslinking agents (HP:0003221)2.21256597
58Neoplasm of the oral cavity (HP:0100649)2.20085495
59Insomnia (HP:0100785)2.18808754
60Abnormality of skeletal muscle fiber size (HP:0012084)2.17776500
61Spinal rigidity (HP:0003306)2.17244752
62Broad thumb (HP:0011304)2.16524741
63Bicornuate uterus (HP:0000813)2.15849784
64Mildly elevated creatine phosphokinase (HP:0008180)2.14718654
65Lipoatrophy (HP:0100578)2.14707258
66Hypotrichosis (HP:0001006)2.14644758
67Atresia of the external auditory canal (HP:0000413)2.14039886
68Bilateral microphthalmos (HP:0007633)2.11755775
69Pili torti (HP:0003777)2.11289011
70Abnormality of the calf musculature (HP:0001430)2.11029964
71Premature rupture of membranes (HP:0001788)2.10720967
72Broad distal phalanx of finger (HP:0009836)2.10417539
73Ulnar bowing (HP:0003031)2.10301824
74Subaortic stenosis (HP:0001682)2.09618112
75Abnormality of the left ventricular outflow tract (HP:0011103)2.09618112
76Absent eyelashes (HP:0000561)2.09161777
77Abnormal number of incisors (HP:0011064)2.08159473
78Difficulty climbing stairs (HP:0003551)2.05612871
79Bowel diverticulosis (HP:0005222)2.04804025
80Dysmetric saccades (HP:0000641)2.04778485
81Exercise-induced muscle cramps (HP:0003710)2.04030518
82Abnormality of the aortic arch (HP:0012303)2.03341913
83Trigonocephaly (HP:0000243)2.03241093
84Cutaneous finger syndactyly (HP:0010554)2.01952708
85Duplication of thumb phalanx (HP:0009942)2.00062697
86Cortical dysplasia (HP:0002539)1.97604754
87Abnormality of the distal phalanx of the thumb (HP:0009617)1.96464690
88Wrist flexion contracture (HP:0001239)1.96440314
89Disproportionate tall stature (HP:0001519)1.96069299
90Partial duplication of thumb phalanx (HP:0009944)1.94903415
91Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.94893192
92Shawl scrotum (HP:0000049)1.94278489
93Broad phalanges of the hand (HP:0009768)1.94019411
94Bronchomalacia (HP:0002780)1.93876595
95Ectopic kidney (HP:0000086)1.93757028
96Mitral valve prolapse (HP:0001634)1.91790841
97Abnormality of the parathyroid morphology (HP:0011766)1.91462690
98Medulloblastoma (HP:0002885)1.91435060
99Intestinal polyp (HP:0005266)1.91366858
100Fibroma (HP:0010614)1.91297783
101Reticulocytopenia (HP:0001896)1.91111680
102Venous insufficiency (HP:0005293)1.91104414
103Chromsome breakage (HP:0040012)1.90198469
104Follicular hyperkeratosis (HP:0007502)1.89875933
105Syncope (HP:0001279)1.89126312
106Spastic diplegia (HP:0001264)1.88800123
107Abnormality of the fingertips (HP:0001211)1.88697876
108Prolonged QT interval (HP:0001657)1.88455416
109Esophageal atresia (HP:0002032)1.87434894
110Short palpebral fissure (HP:0012745)1.86899031
111Aplasia involving bones of the upper limbs (HP:0009823)1.85718431
112Aplasia of the phalanges of the hand (HP:0009802)1.85718431
113Aplasia involving bones of the extremities (HP:0009825)1.85718431
114Long palpebral fissure (HP:0000637)1.85699531
115Myotonia (HP:0002486)1.85620290
116Fibrous tissue neoplasm (HP:0012316)1.85305586
117Sprengel anomaly (HP:0000912)1.84563027
118Selective tooth agenesis (HP:0001592)1.84194342
119Broad finger (HP:0001500)1.84168598
120Metaphyseal cupping (HP:0003021)1.83680428
121Aplasia/Hypoplasia of the sacrum (HP:0008517)1.82724920
122Patellar aplasia (HP:0006443)1.82492198
123Ventricular fibrillation (HP:0001663)1.82367769
124Deformed tarsal bones (HP:0008119)1.81839360
125Absent radius (HP:0003974)1.81566233
126Skin pits (HP:0100276)1.81060921
127Long eyelashes (HP:0000527)1.80998911
128Spina bifida occulta (HP:0003298)1.80977075
129Overgrowth (HP:0001548)1.80347251
130Deviation of the hallux (HP:0010051)1.79824994
131Calf muscle hypertrophy (HP:0008981)1.79633901
132Abnormality of the sella turcica (HP:0002679)1.79142045
133Ankyloglossia (HP:0010296)1.78083687
134Rectal prolapse (HP:0002035)1.77529992
135Hallux valgus (HP:0001822)1.76445338
136Exercise-induced myalgia (HP:0003738)1.75749078
137Hypercalcemia (HP:0003072)1.75502544
138Venous abnormality (HP:0002624)1.75202482
139Intestinal fistula (HP:0100819)1.75027549
140Pointed chin (HP:0000307)1.74227507
141Coronal craniosynostosis (HP:0004440)1.73030395
142Generalized hypotonia (HP:0001290)1.70872671
143Bundle branch block (HP:0011710)1.67824390
144Arnold-Chiari malformation (HP:0002308)1.67612485
145Adducted thumb (HP:0001181)1.67119719
146Breast hypoplasia (HP:0003187)1.67115997
147Hypoventilation (HP:0002791)1.66377118
148Gastrointestinal carcinoma (HP:0002672)1.65987454
149Malignant gastrointestinal tract tumors (HP:0006749)1.65987454
150Hip contracture (HP:0003273)1.65459679
151Partial agenesis of the corpus callosum (HP:0001338)1.65330048
152Absent forearm bone (HP:0003953)1.64217770
153Aplasia involving forearm bones (HP:0009822)1.64217770
154Hamartoma (HP:0010566)1.63839349
155Abnormality of the nasolacrimal system (HP:0000614)1.63839169
156Birth length less than 3rd percentile (HP:0003561)1.63050982
157Scapular winging (HP:0003691)1.62236781
158Limb-girdle muscle weakness (HP:0003325)1.62219747
159Aplasia/Hypoplasia of the patella (HP:0006498)1.61860202
160Atrioventricular block (HP:0001678)1.61403291
161Facial cleft (HP:0002006)1.61063356
162Capillary hemangiomas (HP:0005306)1.61012693
163Neonatal death (HP:0003811)1.60960443
164Abnormal ventriculo-arterial connection (HP:0011563)1.60924973
165Transposition of the great arteries (HP:0001669)1.60924973
166Abnormal connection of the cardiac segments (HP:0011545)1.60924973
167Pulmonary artery stenosis (HP:0004415)1.60236884
168Annular pancreas (HP:0001734)1.59736415
169Anal stenosis (HP:0002025)1.59669826
170Proximal placement of thumb (HP:0009623)1.59253541
171Deviation of the thumb (HP:0009603)1.59124452
172Vaginal fistula (HP:0004320)1.58841800
173Precocious puberty (HP:0000826)1.58737240
174Abnormality of abdominal situs (HP:0011620)1.58727445
175Abdominal situs inversus (HP:0003363)1.58727445
176Broad phalanx (HP:0006009)1.58692905
177Thin ribs (HP:0000883)1.57566918

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE15.21535263
2EPHB23.98061753
3PKN23.50748802
4SMG13.50618699
5TRIB33.47121853
6CDC72.86466343
7RIPK12.73158637
8KDR2.61794348
9TTN2.61325717
10MAP3K102.48912335
11PDGFRA2.11337448
12ICK2.04995119
13LATS21.90464206
14PLK41.87436486
15TTK1.83499448
16PTK61.80874183
17PHKG11.80616421
18PHKG21.80616421
19CDK121.78411515
20EEF2K1.64823982
21MARK11.63376991
22LMTK21.61838540
23TGFBR11.60037682
24TAF11.59770231
25TYRO31.56640021
26LATS11.54182239
27DMPK1.54025526
28SIK21.45391704
29FER1.37813754
30CHEK21.34128524
31SIK11.33122008
32PRKD31.32990520
33PRPF4B1.26108345
34FGFR41.25934184
35DDR21.23997125
36SRPK11.20696645
37BUB11.20681988
38TGFBR21.14474806
39MTOR1.14091353
40PTK21.10723526
41PAK41.08442408
42DYRK31.08435075
43CDK71.07351952
44VRK21.05289727
45PBK1.02801403
46CDC42BPA1.02068261
47RET1.00141393
48ILK0.99634524
49STK40.99387345
50ATR0.98279541
51RPS6KB20.96031113
52MYLK0.95799721
53FGFR10.95751046
54CAMK1G0.95238367
55FGFR20.93831317
56ZAK0.93467666
57NEK10.92541832
58AURKA0.91545664
59PTK2B0.90823304
60CHEK10.88056186
61PRKD10.87371632
62NEK20.86702560
63ALK0.85170786
64ROCK10.82335414
65NME20.82238573
66EIF2AK10.81116334
67PLK10.80387407
68INSRR0.80106943
69PAK20.79660588
70CAMK40.79019827
71CAMK1D0.78493943
72PDGFRB0.74234141
73ERBB20.70792255
74NME10.70725634
75CDK20.69941813
76BMX0.69674560
77BRAF0.68883875
78PAK30.68278009
79DYRK20.67937420
80PRKCI0.67862708
81TSSK60.67517862
82PASK0.67111935
83AURKB0.64102680
84MAP3K90.64020056
85CDK10.63303502
86CDK190.62109623
87UHMK10.61674439
88RPS6KA60.61314754
89MET0.60569693
90AKT20.59515906
91MAP2K20.59266004
92MKNK20.58860215
93BRD40.57450510
94MAP3K80.56160870
95ATM0.55886025
96CSNK1A1L0.55780304
97OBSCN0.55395593
98KSR10.54195650
99PIM10.54184782
100CASK0.54069566
101PAK60.54066264
102ROCK20.51640364
103LRRK20.51610253
104PLK30.51339636
105DAPK20.51287370
106NTRK20.51092949
107MAP3K70.50829197
108MAP3K40.50195547
109DAPK30.50153672
110EPHB10.50096163
111MKNK10.49825681
112BRSK10.48781526
113CDK60.48507163
114RPS6KA10.47649632
115RPS6KA50.47519056
116RPS6KA20.46319088
117CLK10.45864711
118GSK3A0.45101455
119TAOK10.44058564
120MARK20.43976208
121PRKDC0.43924145
122GSK3B0.43901753
123NTRK10.42848296
124RPS6KL10.42590664
125RPS6KC10.42590664
126TLK10.41601595
127MAP3K60.41562015
128CDK11A0.40574204
129CDK40.40275893
130PDK30.39615796
131PDK40.39615796
132MAPK140.39022949
133PRKAA10.38912454
134STK110.38154586
135PRKG20.37506560
136CDK150.37300820
137MAPK80.36988880
138DYRK1B0.36631803
139SCYL20.35485215
140SRC0.35437609
141MAPK90.34216972
142AKT10.33953045
143CSNK1G30.32725668
144PNCK0.32239964
145CSNK1G10.31403263
146CSNK1D0.30773641
147CSNK1E0.30707813

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal cell carcinoma_Homo sapiens_hsa052173.77782470
2DNA replication_Homo sapiens_hsa030303.36540740
3Hedgehog signaling pathway_Homo sapiens_hsa043402.94814457
4ECM-receptor interaction_Homo sapiens_hsa045122.53836499
5Dilated cardiomyopathy_Homo sapiens_hsa054142.47371856
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.32237550
7Notch signaling pathway_Homo sapiens_hsa043302.29461520
8Cell cycle_Homo sapiens_hsa041102.24654122
9Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.15897343
10Hippo signaling pathway_Homo sapiens_hsa043902.08805112
11Axon guidance_Homo sapiens_hsa043602.06109981
12Mismatch repair_Homo sapiens_hsa034302.04030215
13Focal adhesion_Homo sapiens_hsa045102.01091809
14Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.96616607
15Base excision repair_Homo sapiens_hsa034101.93183099
16Spliceosome_Homo sapiens_hsa030401.92523049
17Adherens junction_Homo sapiens_hsa045201.91386198
18Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.91187186
19Viral myocarditis_Homo sapiens_hsa054161.72277803
20Biosynthesis of amino acids_Homo sapiens_hsa012301.69645779
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.66427382
22RNA transport_Homo sapiens_hsa030131.65892866
23Dorso-ventral axis formation_Homo sapiens_hsa043201.64343592
242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.62551097
25Tight junction_Homo sapiens_hsa045301.60642722
26Proteoglycans in cancer_Homo sapiens_hsa052051.59687295
27Melanogenesis_Homo sapiens_hsa049161.59581695
28Cardiac muscle contraction_Homo sapiens_hsa042601.56950116
29Small cell lung cancer_Homo sapiens_hsa052221.55014671
30Non-homologous end-joining_Homo sapiens_hsa034501.50872709
31Wnt signaling pathway_Homo sapiens_hsa043101.45997417
32Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.39813950
33MicroRNAs in cancer_Homo sapiens_hsa052061.39060313
34Lysine degradation_Homo sapiens_hsa003101.37771262
35Central carbon metabolism in cancer_Homo sapiens_hsa052301.37196773
36Thyroid hormone signaling pathway_Homo sapiens_hsa049191.36479934
37Amoebiasis_Homo sapiens_hsa051461.36463469
38Protein digestion and absorption_Homo sapiens_hsa049741.34584853
39Ribosome_Homo sapiens_hsa030101.32472404
40Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.32335594
41Endometrial cancer_Homo sapiens_hsa052131.31025908
42Pathways in cancer_Homo sapiens_hsa052001.29527134
43Renal cell carcinoma_Homo sapiens_hsa052111.27375492
44Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.24879264
45Sulfur relay system_Homo sapiens_hsa041221.24569769
46Estrogen signaling pathway_Homo sapiens_hsa049151.20050940
47Thyroid cancer_Homo sapiens_hsa052161.17611412
48AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.16751512
49Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.16143006
50VEGF signaling pathway_Homo sapiens_hsa043701.14991451
51Rap1 signaling pathway_Homo sapiens_hsa040151.12999425
52Gap junction_Homo sapiens_hsa045401.12390903
53Insulin resistance_Homo sapiens_hsa049311.12321361
54TGF-beta signaling pathway_Homo sapiens_hsa043501.10190916
55Nucleotide excision repair_Homo sapiens_hsa034201.08755521
56Colorectal cancer_Homo sapiens_hsa052101.07432700
57Cysteine and methionine metabolism_Homo sapiens_hsa002701.02878058
58Insulin signaling pathway_Homo sapiens_hsa049101.02188655
59cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01194038
60Selenocompound metabolism_Homo sapiens_hsa004501.00790196
61Fanconi anemia pathway_Homo sapiens_hsa034600.99669624
62AMPK signaling pathway_Homo sapiens_hsa041520.98236532
63Chronic myeloid leukemia_Homo sapiens_hsa052200.96417573
64mTOR signaling pathway_Homo sapiens_hsa041500.96284337
65Pentose phosphate pathway_Homo sapiens_hsa000300.96123663
66PI3K-Akt signaling pathway_Homo sapiens_hsa041510.92292560
67HIF-1 signaling pathway_Homo sapiens_hsa040660.89761864
68Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.88988556
69Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.88890523
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.87621958
71Glioma_Homo sapiens_hsa052140.86219180
72Longevity regulating pathway - mammal_Homo sapiens_hsa042110.85488102
73Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.85132785
74Glucagon signaling pathway_Homo sapiens_hsa049220.85055189
75Renin secretion_Homo sapiens_hsa049240.83692396
76HTLV-I infection_Homo sapiens_hsa051660.83640808
77Systemic lupus erythematosus_Homo sapiens_hsa053220.82228504
78Oxytocin signaling pathway_Homo sapiens_hsa049210.80947737
79Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.80941323
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80641361
81GnRH signaling pathway_Homo sapiens_hsa049120.80615176
82Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.79850382
83Homologous recombination_Homo sapiens_hsa034400.79789579
84Adipocytokine signaling pathway_Homo sapiens_hsa049200.79168495
85Regulation of actin cytoskeleton_Homo sapiens_hsa048100.78088665
86mRNA surveillance pathway_Homo sapiens_hsa030150.77955955
87Aldosterone synthesis and secretion_Homo sapiens_hsa049250.77897628
88Pyrimidine metabolism_Homo sapiens_hsa002400.77170465
89Leukocyte transendothelial migration_Homo sapiens_hsa046700.76300523
90Bladder cancer_Homo sapiens_hsa052190.76032000
91Folate biosynthesis_Homo sapiens_hsa007900.75166958
92Type II diabetes mellitus_Homo sapiens_hsa049300.74724863
93Pancreatic cancer_Homo sapiens_hsa052120.73557981
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.72855860
95Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.71827298
96Neurotrophin signaling pathway_Homo sapiens_hsa047220.71579437
97Vascular smooth muscle contraction_Homo sapiens_hsa042700.71416283
98cAMP signaling pathway_Homo sapiens_hsa040240.71265373
99Vitamin B6 metabolism_Homo sapiens_hsa007500.67565515
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.67358631
101Non-small cell lung cancer_Homo sapiens_hsa052230.65862224
102Melanoma_Homo sapiens_hsa052180.65112664
103Ras signaling pathway_Homo sapiens_hsa040140.64722446
104One carbon pool by folate_Homo sapiens_hsa006700.63569856
105Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.62791810
106Platelet activation_Homo sapiens_hsa046110.62563693
107Toxoplasmosis_Homo sapiens_hsa051450.62435839
108Ovarian steroidogenesis_Homo sapiens_hsa049130.61655890
109Gastric acid secretion_Homo sapiens_hsa049710.61422901
110Viral carcinogenesis_Homo sapiens_hsa052030.60845149
111Prostate cancer_Homo sapiens_hsa052150.58925624
112p53 signaling pathway_Homo sapiens_hsa041150.58893040
113Choline metabolism in cancer_Homo sapiens_hsa052310.58800486
114ErbB signaling pathway_Homo sapiens_hsa040120.58554523
115Oocyte meiosis_Homo sapiens_hsa041140.57651640
116Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56498372
117Pyruvate metabolism_Homo sapiens_hsa006200.56488404
118Arginine biosynthesis_Homo sapiens_hsa002200.56448593
119Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.56116501
120Inositol phosphate metabolism_Homo sapiens_hsa005620.54630108
121Acute myeloid leukemia_Homo sapiens_hsa052210.54506912
122Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.54219171
123Cholinergic synapse_Homo sapiens_hsa047250.53534070
124Circadian entrainment_Homo sapiens_hsa047130.50141342
125MAPK signaling pathway_Homo sapiens_hsa040100.49924482
126Fatty acid degradation_Homo sapiens_hsa000710.49326269
127Cyanoamino acid metabolism_Homo sapiens_hsa004600.49125272
128RNA polymerase_Homo sapiens_hsa030200.48471233
129Propanoate metabolism_Homo sapiens_hsa006400.47796977
130FoxO signaling pathway_Homo sapiens_hsa040680.47519149
131Fatty acid metabolism_Homo sapiens_hsa012120.46955833
132Galactose metabolism_Homo sapiens_hsa000520.46690979
133Carbon metabolism_Homo sapiens_hsa012000.44593365
134PPAR signaling pathway_Homo sapiens_hsa033200.44074416
135Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.43569448
136Alcoholism_Homo sapiens_hsa050340.42685793
137Purine metabolism_Homo sapiens_hsa002300.42621834
138Arginine and proline metabolism_Homo sapiens_hsa003300.40793630
139Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39241703

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