Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 4.56247384 |
2 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 4.45331420 |
3 | cardiac myofibril assembly (GO:0055003) | 4.43296709 |
4 | heterochromatin organization (GO:0070828) | 4.28445829 |
5 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 4.14737481 |
6 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 4.00047788 |
7 | regulation of gene silencing by RNA (GO:0060966) | 3.94654171 |
8 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.94654171 |
9 | regulation of gene silencing by miRNA (GO:0060964) | 3.94654171 |
10 | lateral sprouting from an epithelium (GO:0060601) | 3.94518145 |
11 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.91982624 |
12 | coronary vasculature morphogenesis (GO:0060977) | 3.91860562 |
13 | plasma membrane repair (GO:0001778) | 3.90637909 |
14 | protein complex localization (GO:0031503) | 3.87618679 |
15 | nucleosome disassembly (GO:0006337) | 3.86335368 |
16 | protein-DNA complex disassembly (GO:0032986) | 3.86335368 |
17 | cell migration in hindbrain (GO:0021535) | 3.83000842 |
18 | hemidesmosome assembly (GO:0031581) | 3.81439067 |
19 | polarized epithelial cell differentiation (GO:0030859) | 3.78369297 |
20 | lymph vessel development (GO:0001945) | 3.75694259 |
21 | nuclear pore complex assembly (GO:0051292) | 3.72626618 |
22 | sarcomere organization (GO:0045214) | 3.67947104 |
23 | regulation of cardioblast differentiation (GO:0051890) | 3.64040962 |
24 | convergent extension (GO:0060026) | 3.61824726 |
25 | myofibril assembly (GO:0030239) | 3.47237647 |
26 | histone arginine methylation (GO:0034969) | 3.46080883 |
27 | heart trabecula formation (GO:0060347) | 3.45002897 |
28 | * enteric nervous system development (GO:0048484) | 3.44043621 |
29 | mitotic chromosome condensation (GO:0007076) | 3.44005904 |
30 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 3.38752941 |
31 | heart morphogenesis (GO:0003007) | 3.38729933 |
32 | cell migration involved in heart development (GO:0060973) | 3.35682745 |
33 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.35304130 |
34 | regulation of cardioblast proliferation (GO:0003264) | 3.33815150 |
35 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 3.33815150 |
36 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 3.32480360 |
37 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.30801546 |
38 | hippo signaling (GO:0035329) | 3.30602823 |
39 | anatomical structure regression (GO:0060033) | 3.29579786 |
40 | embryonic foregut morphogenesis (GO:0048617) | 3.26279397 |
41 | protein heterotrimerization (GO:0070208) | 3.22884048 |
42 | nuclear pore organization (GO:0006999) | 3.21267757 |
43 | lymphangiogenesis (GO:0001946) | 3.20551464 |
44 | paraxial mesoderm development (GO:0048339) | 3.19958763 |
45 | positive regulation of G2/M transition of mitotic cell cycle (GO:0010971) | 3.18828193 |
46 | positive regulation of cell cycle G2/M phase transition (GO:1902751) | 3.18828193 |
47 | basement membrane organization (GO:0071711) | 3.16524999 |
48 | positive regulation of transcription regulatory region DNA binding (GO:2000679) | 3.14861826 |
49 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.13418737 |
50 | axon extension involved in axon guidance (GO:0048846) | 3.13418737 |
51 | establishment of apical/basal cell polarity (GO:0035089) | 3.12824516 |
52 | establishment of tissue polarity (GO:0007164) | 3.11820736 |
53 | establishment of planar polarity (GO:0001736) | 3.11820736 |
54 | DNA replication initiation (GO:0006270) | 3.10089356 |
55 | negative regulation of catenin import into nucleus (GO:0035414) | 3.10072167 |
56 | semaphorin-plexin signaling pathway (GO:0071526) | 3.09810643 |
57 | chromatin assembly (GO:0031497) | 3.08341673 |
58 | cellular protein complex localization (GO:0034629) | 3.08103266 |
59 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 3.07300047 |
60 | cardiac muscle cell development (GO:0055013) | 3.05579274 |
61 | cardiac ventricle formation (GO:0003211) | 3.05442600 |
62 | cardiac chamber formation (GO:0003207) | 3.05348960 |
63 | L-serine metabolic process (GO:0006563) | 3.03594634 |
64 | layer formation in cerebral cortex (GO:0021819) | 3.03465286 |
65 | trabecula formation (GO:0060343) | 3.02141757 |
66 | adult heart development (GO:0007512) | 3.01943605 |
67 | cardiac cell development (GO:0055006) | 3.01066284 |
68 | ventricular cardiac muscle cell action potential (GO:0086005) | 3.00114620 |
69 | notochord development (GO:0030903) | 2.97966026 |
70 | proximal/distal pattern formation (GO:0009954) | 2.96787696 |
71 | molting cycle (GO:0042303) | 2.94502175 |
72 | hair cycle (GO:0042633) | 2.94502175 |
73 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.94246402 |
74 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.94005905 |
75 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.93964448 |
76 | non-canonical Wnt signaling pathway (GO:0035567) | 2.93766634 |
77 | embryonic heart tube development (GO:0035050) | 2.93537315 |
78 | protein localization to chromosome, centromeric region (GO:0071459) | 2.91493314 |
79 | adherens junction assembly (GO:0034333) | 2.91361678 |
80 | apoptotic process involved in morphogenesis (GO:0060561) | 2.90519401 |
81 | negative regulation of histone methylation (GO:0031061) | 2.89242623 |
82 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.87894024 |
83 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.87444687 |
84 | negative regulation of cell fate specification (GO:0009996) | 2.86832635 |
85 | establishment of integrated proviral latency (GO:0075713) | 2.86824343 |
86 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.86095503 |
87 | DNA strand elongation (GO:0022616) | 2.85859566 |
88 | morphogenesis of an endothelium (GO:0003159) | 2.85357431 |
89 | endothelial tube morphogenesis (GO:0061154) | 2.85357431 |
90 | mesenchymal cell proliferation (GO:0010463) | 2.85145773 |
91 | establishment of monopolar cell polarity (GO:0061162) | 2.84651360 |
92 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.84651360 |
93 | protein localization to kinetochore (GO:0034501) | 2.84089457 |
94 | regulation of hippo signaling (GO:0035330) | 2.83511704 |
95 | cell-substrate junction assembly (GO:0007044) | 2.81860497 |
96 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 2.81828149 |
97 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 2.80575387 |
98 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.80266319 |
99 | regulation of heart morphogenesis (GO:2000826) | 2.79699736 |
100 | peptidyl-arginine N-methylation (GO:0035246) | 2.78041606 |
101 | peptidyl-arginine methylation (GO:0018216) | 2.78041606 |
102 | cardiac muscle cell proliferation (GO:0060038) | 2.77625571 |
103 | renal system development (GO:0072001) | 2.77576849 |
104 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.77257143 |
105 | regulation of translational fidelity (GO:0006450) | 2.76945063 |
106 | neural tube development (GO:0021915) | 2.76672072 |
107 | lung-associated mesenchyme development (GO:0060484) | 2.76027257 |
108 | regulation of establishment of planar polarity (GO:0090175) | 2.75686931 |
109 | regulation of transcription from RNA polymerase II promoter involved in heart development (GO:190121 | 2.75643883 |
110 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 2.75273353 |
111 | vasculogenesis (GO:0001570) | 2.74801822 |
112 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 2.74643440 |
113 | head development (GO:0060322) | 2.74360419 |
114 | peripheral nervous system neuron development (GO:0048935) | 2.74198577 |
115 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 2.73205875 |
116 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.72991919 |
117 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.72159007 |
118 | sympathetic nervous system development (GO:0048485) | 2.71347853 |
119 | bone trabecula formation (GO:0060346) | 2.70819911 |
120 | endothelial cell differentiation (GO:0045446) | 2.70806436 |
121 | mRNA stabilization (GO:0048255) | 2.70523008 |
122 | RNA stabilization (GO:0043489) | 2.70523008 |
123 | ectodermal placode formation (GO:0060788) | 2.70504609 |
124 | actomyosin structure organization (GO:0031032) | 2.70086239 |
125 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.69571363 |
126 | mitotic sister chromatid cohesion (GO:0007064) | 2.69116088 |
127 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.68896808 |
128 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 2.68880342 |
129 | patterning of blood vessels (GO:0001569) | 2.68459906 |
130 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.68161053 |
131 | gastrulation with mouth forming second (GO:0001702) | 2.68101392 |
132 | regulation of NFAT protein import into nucleus (GO:0051532) | 2.66664420 |
133 | pre-miRNA processing (GO:0031054) | 2.66378306 |
134 | regulation of RNA export from nucleus (GO:0046831) | 2.66322601 |
135 | DNA duplex unwinding (GO:0032508) | 2.66212626 |
136 | apoptotic process involved in development (GO:1902742) | 2.65695811 |
137 | regulation of cell fate specification (GO:0042659) | 2.64140970 |
138 | mitotic sister chromatid segregation (GO:0000070) | 2.64126462 |
139 | blood vessel endothelial cell migration (GO:0043534) | 2.63961261 |
140 | regulation of stem cell maintenance (GO:2000036) | 2.63501716 |
141 | regulation of cell proliferation involved in heart morphogenesis (GO:2000136) | 2.62150921 |
142 | cardiac muscle contraction (GO:0060048) | 2.61983336 |
143 | mesenchyme morphogenesis (GO:0072132) | 2.61667892 |
144 | regulation of histone H3-K9 methylation (GO:0051570) | 2.61148000 |
145 | atrial septum morphogenesis (GO:0060413) | 2.60190244 |
146 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.59795921 |
147 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.59795921 |
148 | outflow tract septum morphogenesis (GO:0003148) | 2.59579805 |
149 | outer ear morphogenesis (GO:0042473) | 2.58768604 |
150 | atrioventricular valve morphogenesis (GO:0003181) | 2.57705612 |
151 | ganglion development (GO:0061548) | 2.57575894 |
152 | desmosome organization (GO:0002934) | 2.56586577 |
153 | cell communication involved in cardiac conduction (GO:0086065) | 2.55572423 |
154 | pore complex assembly (GO:0046931) | 2.54787568 |
155 | endocardial cushion morphogenesis (GO:0003203) | 2.54391718 |
156 | cardiac muscle tissue morphogenesis (GO:0055008) | 2.53947135 |
157 | blood vessel maturation (GO:0001955) | 2.53212849 |
158 | glial cell proliferation (GO:0014009) | 2.53191097 |
159 | sister chromatid segregation (GO:0000819) | 2.52459357 |
160 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.52249741 |
161 | odontogenesis of dentin-containing tooth (GO:0042475) | 2.52140917 |
162 | chromatin silencing (GO:0006342) | 2.51632942 |
163 | DNA geometric change (GO:0032392) | 2.49948576 |
164 | regulation of chromatin binding (GO:0035561) | 2.47064262 |
165 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.46704026 |
166 | peptidyl-lysine dimethylation (GO:0018027) | 2.41256990 |
167 | L-alpha-amino acid transmembrane transport (GO:1902475) | 2.40601800 |
168 | DNA topological change (GO:0006265) | 2.40363406 |
169 | embryonic body morphogenesis (GO:0010172) | 2.39022146 |
170 | intracellular estrogen receptor signaling pathway (GO:0030520) | 2.36719260 |
171 | negative regulation of DNA repair (GO:0045738) | 2.36050910 |
172 | regulation of catenin import into nucleus (GO:0035412) | 2.36003897 |
173 | body morphogenesis (GO:0010171) | 2.34835160 |
174 | chromatin assembly or disassembly (GO:0006333) | 2.34724967 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.97552872 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.63674162 |
3 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 4.10430416 |
4 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.83406007 |
5 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.78372165 |
6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.75218025 |
7 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.57900185 |
8 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.57486680 |
9 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.35808964 |
10 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 2.27910035 |
11 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.27164611 |
12 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.25599675 |
13 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 2.22725831 |
14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.22341269 |
15 | KDM2B_26808549_Chip-Seq_K562_Human | 2.18574823 |
16 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 2.12355641 |
17 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.11444859 |
18 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.02833348 |
19 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.02802819 |
20 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.98619042 |
21 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.98619042 |
22 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.95794478 |
23 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.95110040 |
24 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.95110040 |
25 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.95110040 |
26 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.94108278 |
27 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.91457144 |
28 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.90171729 |
29 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.87972092 |
30 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.84866399 |
31 | * ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.82662461 |
32 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.82223426 |
33 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.80840317 |
34 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.77789094 |
35 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.74054354 |
36 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.73739630 |
37 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.73156989 |
38 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.73113803 |
39 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.69533801 |
40 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.67549612 |
41 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.67229670 |
42 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.66597740 |
43 | * KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.63155631 |
44 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.63124860 |
45 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.61902266 |
46 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.60539337 |
47 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.60206138 |
48 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.59179558 |
49 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.58346138 |
50 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.58200406 |
51 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.58200406 |
52 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.57817981 |
53 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.56609678 |
54 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.56497244 |
55 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.54241164 |
56 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.52532005 |
57 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.51894498 |
58 | * UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.50329641 |
59 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.49524525 |
60 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.49140942 |
61 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.47568234 |
62 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.46070124 |
63 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.45586929 |
64 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.45578976 |
65 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.44806458 |
66 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.44462614 |
67 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.42633256 |
68 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.42109665 |
69 | * ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.41558090 |
70 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.41536833 |
71 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.41332374 |
72 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.40442345 |
73 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.38853301 |
74 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.38314571 |
75 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.38303649 |
76 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.37755479 |
77 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.37580270 |
78 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.37400053 |
79 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.37253197 |
80 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.36962222 |
81 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.36762667 |
82 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.35848221 |
83 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.34227101 |
84 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.34116204 |
85 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.33513103 |
86 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.32952704 |
87 | * CTCF_27219007_Chip-Seq_Bcells_Human | 1.30809910 |
88 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.30340397 |
89 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.30054087 |
90 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.29736660 |
91 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.29521926 |
92 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.28661932 |
93 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.28004944 |
94 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.27986879 |
95 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.27564477 |
96 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.26315539 |
97 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.26228878 |
98 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.25090497 |
99 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.24646933 |
100 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.24066201 |
101 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.24040669 |
102 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.23554878 |
103 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.23349054 |
104 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.22954219 |
105 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21138811 |
106 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.20813081 |
107 | * OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.20478478 |
108 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.20457741 |
109 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.19903983 |
110 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.19167930 |
111 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.17881196 |
112 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.17210921 |
113 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.16758560 |
114 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.16383172 |
115 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.16280260 |
116 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.14453493 |
117 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.14109651 |
118 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.12657104 |
119 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.11557076 |
120 | MYC_22102868_ChIP-Seq_BL_Human | 1.11267061 |
121 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.11104767 |
122 | * P68_20966046_ChIP-Seq_HELA_Human | 1.10492635 |
123 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.10443484 |
124 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.09991096 |
125 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.09627796 |
126 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.09415273 |
127 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.09264699 |
128 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.08903094 |
129 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.07702702 |
130 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.07502840 |
131 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.07023056 |
132 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.06792600 |
133 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.06674206 |
134 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.05790923 |
135 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.05589167 |
136 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.05575558 |
137 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.05102704 |
138 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.04704857 |
139 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.04149796 |
140 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.03977255 |
141 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.03250454 |
142 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02866537 |
143 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.02641457 |
144 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.02614802 |
145 | * SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.02022771 |
146 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.00266420 |
147 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.99952069 |
148 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.99907557 |
149 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.98738743 |
150 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.97113057 |
151 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.97047764 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004084_abnormal_cardiac_muscle | 3.43371257 |
2 | MP0003705_abnormal_hypodermis_morpholog | 3.38989602 |
3 | MP0004272_abnormal_basement_membrane | 3.37563195 |
4 | MP0000751_myopathy | 3.04427659 |
5 | MP0010368_abnormal_lymphatic_system | 2.92484595 |
6 | MP0000537_abnormal_urethra_morphology | 2.51191857 |
7 | MP0002837_dystrophic_cardiac_calcinosis | 2.37552502 |
8 | MP0003111_abnormal_nucleus_morphology | 2.34983564 |
9 | MP0002822_catalepsy | 2.33441313 |
10 | MP0003693_abnormal_embryo_hatching | 2.30103442 |
11 | MP0004215_abnormal_myocardial_fiber | 2.20247599 |
12 | MP0001879_abnormal_lymphatic_vessel | 2.18107262 |
13 | MP0006138_congestive_heart_failure | 2.12670744 |
14 | MP0004957_abnormal_blastocyst_morpholog | 2.08830818 |
15 | MP0002697_abnormal_eye_size | 2.06161227 |
16 | MP0003122_maternal_imprinting | 1.99887561 |
17 | MP0002009_preneoplasia | 1.98479897 |
18 | MP0005623_abnormal_meninges_morphology | 1.97591233 |
19 | MP0009672_abnormal_birth_weight | 1.97245837 |
20 | MP0003567_abnormal_fetal_cardiomyocyte | 1.95837208 |
21 | MP0003646_muscle_fatigue | 1.95379698 |
22 | MP0004036_abnormal_muscle_relaxation | 1.94311160 |
23 | MP0002653_abnormal_ependyma_morphology | 1.94280923 |
24 | MP0005167_abnormal_blood-brain_barrier | 1.90988816 |
25 | MP0002234_abnormal_pharynx_morphology | 1.88027790 |
26 | MP0009053_abnormal_anal_canal | 1.85509123 |
27 | MP0010030_abnormal_orbit_morphology | 1.84840699 |
28 | MP0001730_embryonic_growth_arrest | 1.84545478 |
29 | MP0005330_cardiomyopathy | 1.82738697 |
30 | MP0003385_abnormal_body_wall | 1.82187246 |
31 | MP0008932_abnormal_embryonic_tissue | 1.78110429 |
32 | MP0005187_abnormal_penis_morphology | 1.76838675 |
33 | MP0003077_abnormal_cell_cycle | 1.75129999 |
34 | MP0008438_abnormal_cutaneous_collagen | 1.73921508 |
35 | MP0010630_abnormal_cardiac_muscle | 1.70850889 |
36 | MP0010094_abnormal_chromosome_stability | 1.70656109 |
37 | MP0005275_abnormal_skin_tensile | 1.69233527 |
38 | MP0003123_paternal_imprinting | 1.67978143 |
39 | MP0000579_abnormal_nail_morphology | 1.65251998 |
40 | MP0003890_abnormal_embryonic-extraembry | 1.60805838 |
41 | MP0004087_abnormal_muscle_fiber | 1.60129575 |
42 | MP0000750_abnormal_muscle_regeneration | 1.59340621 |
43 | MP0005385_cardiovascular_system_phenoty | 1.57001475 |
44 | MP0001544_abnormal_cardiovascular_syste | 1.57001475 |
45 | MP0000049_abnormal_middle_ear | 1.56788615 |
46 | MP0008775_abnormal_heart_ventricle | 1.56163033 |
47 | MP0002972_abnormal_cardiac_muscle | 1.55958896 |
48 | MP0002127_abnormal_cardiovascular_syste | 1.52769669 |
49 | MP0003119_abnormal_digestive_system | 1.51008691 |
50 | MP0003137_abnormal_impulse_conducting | 1.49948075 |
51 | MP0006054_spinal_hemorrhage | 1.44686297 |
52 | MP0000566_synostosis | 1.42240254 |
53 | MP0003935_abnormal_craniofacial_develop | 1.41604505 |
54 | * MP0002751_abnormal_autonomic_nervous | 1.39973910 |
55 | MP0000383_abnormal_hair_follicle | 1.38662541 |
56 | MP0001293_anophthalmia | 1.37722934 |
57 | MP0005076_abnormal_cell_differentiation | 1.37470521 |
58 | MP0003878_abnormal_ear_physiology | 1.37091837 |
59 | MP0005377_hearing/vestibular/ear_phenot | 1.37091837 |
60 | MP0000428_abnormal_craniofacial_morphol | 1.35562481 |
61 | MP0000733_abnormal_muscle_development | 1.34407716 |
62 | MP0005620_abnormal_muscle_contractility | 1.31181707 |
63 | MP0004233_abnormal_muscle_weight | 1.30714718 |
64 | MP0001849_ear_inflammation | 1.29574885 |
65 | MP0002092_abnormal_eye_morphology | 1.28762121 |
66 | MP0002106_abnormal_muscle_physiology | 1.26763723 |
67 | MP0002080_prenatal_lethality | 1.26634843 |
68 | MP0003828_pulmonary_edema | 1.26069784 |
69 | MP0006292_abnormal_olfactory_placode | 1.25929546 |
70 | MP0008057_abnormal_DNA_replication | 1.24698775 |
71 | MP0003279_aneurysm | 1.23754317 |
72 | MP0000534_abnormal_ureter_morphology | 1.23582369 |
73 | MP0004085_abnormal_heartbeat | 1.23463618 |
74 | MP0003121_genomic_imprinting | 1.22973564 |
75 | MP0001697_abnormal_embryo_size | 1.22480494 |
76 | MP0002249_abnormal_larynx_morphology | 1.22391091 |
77 | MP0003115_abnormal_respiratory_system | 1.22316746 |
78 | MP0004858_abnormal_nervous_system | 1.21373073 |
79 | MP0002925_abnormal_cardiovascular_devel | 1.20931116 |
80 | MP0000762_abnormal_tongue_morphology | 1.20474108 |
81 | MP0000350_abnormal_cell_proliferation | 1.20223924 |
82 | MP0010678_abnormal_skin_adnexa | 1.20053897 |
83 | MP0004484_altered_response_of | 1.19074459 |
84 | MP0005409_darkened_coat_color | 1.19021793 |
85 | MP0002638_abnormal_pupillary_reflex | 1.18537522 |
86 | MP0004145_abnormal_muscle_electrophysio | 1.18058022 |
87 | MP0003942_abnormal_urinary_system | 1.17517746 |
88 | MP0001188_hyperpigmentation | 1.17342882 |
89 | MP0000778_abnormal_nervous_system | 1.17147757 |
90 | MP0010234_abnormal_vibrissa_follicle | 1.16955325 |
91 | MP0002254_reproductive_system_inflammat | 1.16041250 |
92 | MP0003566_abnormal_cell_adhesion | 1.15959303 |
93 | MP0001299_abnormal_eye_distance/ | 1.14472577 |
94 | MP0003755_abnormal_palate_morphology | 1.13295666 |
95 | MP0004133_heterotaxia | 1.12976081 |
96 | MP0000266_abnormal_heart_morphology | 1.12256871 |
97 | MP0003937_abnormal_limbs/digits/tail_de | 1.11236107 |
98 | MP0001286_abnormal_eye_development | 1.09873080 |
99 | MP0002098_abnormal_vibrissa_morphology | 1.09099345 |
100 | MP0002111_abnormal_tail_morphology | 1.08252374 |
101 | MP0002086_abnormal_extraembryonic_tissu | 1.07389313 |
102 | MP0000759_abnormal_skeletal_muscle | 1.06763749 |
103 | MP0001346_abnormal_lacrimal_gland | 1.06640243 |
104 | MP0009703_decreased_birth_body | 1.05909463 |
105 | MP0005369_muscle_phenotype | 1.04922523 |
106 | MP0004197_abnormal_fetal_growth/weight/ | 1.04276449 |
107 | MP0002282_abnormal_trachea_morphology | 1.03993209 |
108 | MP0000467_abnormal_esophagus_morphology | 1.02730164 |
109 | MP0000749_muscle_degeneration | 1.02660074 |
110 | MP0000767_abnormal_smooth_muscle | 1.01949277 |
111 | MP0004185_abnormal_adipocyte_glucose | 1.01859677 |
112 | MP0003941_abnormal_skin_development | 1.01743853 |
113 | MP0004130_abnormal_muscle_cell | 0.99484748 |
114 | MP0002088_abnormal_embryonic_growth/wei | 0.98796794 |
115 | MP0005248_abnormal_Harderian_gland | 0.98577210 |
116 | MP0003984_embryonic_growth_retardation | 0.97783827 |
117 | MP0000462_abnormal_digestive_system | 0.97741291 |
118 | MP0005367_renal/urinary_system_phenotyp | 0.97696726 |
119 | MP0000516_abnormal_urinary_system | 0.97696726 |
120 | MP0005666_abnormal_adipose_tissue | 0.97532411 |
121 | MP0002116_abnormal_craniofacial_bone | 0.97176324 |
122 | MP0002128_abnormal_blood_circulation | 0.96247536 |
123 | MP0002081_perinatal_lethality | 0.95927157 |
124 | MP0002084_abnormal_developmental_patter | 0.95909998 |
125 | MP0000003_abnormal_adipose_tissue | 0.95631299 |
126 | MP0000432_abnormal_head_morphology | 0.95367626 |
127 | MP0001672_abnormal_embryogenesis/_devel | 0.92895378 |
128 | MP0005380_embryogenesis_phenotype | 0.92895378 |
129 | MP0002085_abnormal_embryonic_tissue | 0.92835989 |
130 | MP0005375_adipose_tissue_phenotype | 0.92602660 |
131 | MP0002184_abnormal_innervation | 0.91623933 |
132 | MP0010307_abnormal_tumor_latency | 0.91456842 |
133 | MP0009379_abnormal_foot_pigmentation | 0.91398432 |
134 | MP0002932_abnormal_joint_morphology | 0.91285960 |
135 | MP0009250_abnormal_appendicular_skeleto | 0.90363093 |
136 | MP0002896_abnormal_bone_mineralization | 0.89624121 |
137 | MP0009278_abnormal_bone_marrow | 0.89368049 |
138 | * MP0003861_abnormal_nervous_system | 0.89277176 |
139 | MP0001958_emphysema | 0.88058861 |
140 | MP0005670_abnormal_white_adipose | 0.87892949 |
141 | MP0002114_abnormal_axial_skeleton | 0.86962611 |
142 | MP0002233_abnormal_nose_morphology | 0.86707400 |
143 | MP0000955_abnormal_spinal_cord | 0.86624782 |
144 | MP0010352_gastrointestinal_tract_polyps | 0.84630700 |
145 | MP0001348_abnormal_lacrimal_gland | 0.83169310 |
146 | MP0005501_abnormal_skin_physiology | 0.83141896 |
147 | MP0004147_increased_porphyrin_level | 0.83125993 |
148 | MP0002108_abnormal_muscle_morphology | 0.81125294 |
149 | MP0002152_abnormal_brain_morphology | 0.80260622 |
150 | MP0008058_abnormal_DNA_repair | 0.79718265 |
151 | MP0003283_abnormal_digestive_organ | 0.79221533 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 5.32118520 |
2 | Short 4th metacarpal (HP:0010044) | 5.32118520 |
3 | Abnormality of the 4th metacarpal (HP:0010012) | 4.56041728 |
4 | Sudden death (HP:0001699) | 3.93607205 |
5 | Milia (HP:0001056) | 3.86240693 |
6 | Increased connective tissue (HP:0009025) | 3.62507357 |
7 | Turricephaly (HP:0000262) | 3.54718319 |
8 | Ventricular tachycardia (HP:0004756) | 3.35132789 |
9 | Shallow orbits (HP:0000586) | 3.29838321 |
10 | Neoplasm of the heart (HP:0100544) | 3.19089067 |
11 | Hyperacusis (HP:0010780) | 3.18741869 |
12 | Lymphangioma (HP:0100764) | 3.17220948 |
13 | Muscle fiber splitting (HP:0003555) | 3.12657030 |
14 | Atrophic scars (HP:0001075) | 3.10619995 |
15 | Renal duplication (HP:0000075) | 3.00799217 |
16 | Bladder diverticulum (HP:0000015) | 2.94862916 |
17 | Right ventricular cardiomyopathy (HP:0011663) | 2.94225222 |
18 | Cerebral aneurysm (HP:0004944) | 2.90198710 |
19 | Renovascular hypertension (HP:0100817) | 2.82425893 |
20 | Short phalanx of the thumb (HP:0009660) | 2.79567073 |
21 | High anterior hairline (HP:0009890) | 2.78732740 |
22 | Overriding aorta (HP:0002623) | 2.78687729 |
23 | Abnormality of the parietal bone (HP:0002696) | 2.77166150 |
24 | Elfin facies (HP:0004428) | 2.76671511 |
25 | Broad metatarsal (HP:0001783) | 2.74289854 |
26 | Supernumerary ribs (HP:0005815) | 2.73025373 |
27 | Down-sloping shoulders (HP:0200021) | 2.70959270 |
28 | Hyporeflexia of lower limbs (HP:0002600) | 2.65010525 |
29 | Partial duplication of the phalanx of hand (HP:0009999) | 2.61594784 |
30 | Asymmetry of the thorax (HP:0001555) | 2.60652129 |
31 | Ankle contracture (HP:0006466) | 2.60310125 |
32 | Protrusio acetabuli (HP:0003179) | 2.58634488 |
33 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.57679556 |
34 | Atrial fibrillation (HP:0005110) | 2.57392143 |
35 | Increased variability in muscle fiber diameter (HP:0003557) | 2.57362546 |
36 | Fragile skin (HP:0001030) | 2.56031499 |
37 | Difficulty running (HP:0009046) | 2.55603171 |
38 | Supraventricular arrhythmia (HP:0005115) | 2.50983862 |
39 | Hepatoblastoma (HP:0002884) | 2.48487399 |
40 | Primary atrial arrhythmia (HP:0001692) | 2.45382114 |
41 | Type 1 muscle fiber predominance (HP:0003803) | 2.44884927 |
42 | Flat cornea (HP:0007720) | 2.36664501 |
43 | Midline defect of the nose (HP:0004122) | 2.36025402 |
44 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.35744304 |
45 | Supraventricular tachycardia (HP:0004755) | 2.34630494 |
46 | Abnormality of the calcaneus (HP:0008364) | 2.33879013 |
47 | Skull defect (HP:0001362) | 2.32968462 |
48 | Abnormality of the diencephalon (HP:0010662) | 2.32040119 |
49 | Neonatal hypoglycemia (HP:0001998) | 2.31367187 |
50 | Calcaneovalgus deformity (HP:0001848) | 2.28492313 |
51 | Woolly hair (HP:0002224) | 2.27919123 |
52 | Choanal stenosis (HP:0000452) | 2.26853474 |
53 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 2.25887680 |
54 | Cutaneous syndactyly (HP:0012725) | 2.25859193 |
55 | Fragile nails (HP:0001808) | 2.23148233 |
56 | Increased nuchal translucency (HP:0010880) | 2.21560586 |
57 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.21256597 |
58 | Neoplasm of the oral cavity (HP:0100649) | 2.20085495 |
59 | Insomnia (HP:0100785) | 2.18808754 |
60 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.17776500 |
61 | Spinal rigidity (HP:0003306) | 2.17244752 |
62 | Broad thumb (HP:0011304) | 2.16524741 |
63 | Bicornuate uterus (HP:0000813) | 2.15849784 |
64 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.14718654 |
65 | Lipoatrophy (HP:0100578) | 2.14707258 |
66 | Hypotrichosis (HP:0001006) | 2.14644758 |
67 | Atresia of the external auditory canal (HP:0000413) | 2.14039886 |
68 | Bilateral microphthalmos (HP:0007633) | 2.11755775 |
69 | Pili torti (HP:0003777) | 2.11289011 |
70 | Abnormality of the calf musculature (HP:0001430) | 2.11029964 |
71 | Premature rupture of membranes (HP:0001788) | 2.10720967 |
72 | Broad distal phalanx of finger (HP:0009836) | 2.10417539 |
73 | Ulnar bowing (HP:0003031) | 2.10301824 |
74 | Subaortic stenosis (HP:0001682) | 2.09618112 |
75 | Abnormality of the left ventricular outflow tract (HP:0011103) | 2.09618112 |
76 | Absent eyelashes (HP:0000561) | 2.09161777 |
77 | Abnormal number of incisors (HP:0011064) | 2.08159473 |
78 | Difficulty climbing stairs (HP:0003551) | 2.05612871 |
79 | Bowel diverticulosis (HP:0005222) | 2.04804025 |
80 | Dysmetric saccades (HP:0000641) | 2.04778485 |
81 | Exercise-induced muscle cramps (HP:0003710) | 2.04030518 |
82 | Abnormality of the aortic arch (HP:0012303) | 2.03341913 |
83 | Trigonocephaly (HP:0000243) | 2.03241093 |
84 | Cutaneous finger syndactyly (HP:0010554) | 2.01952708 |
85 | Duplication of thumb phalanx (HP:0009942) | 2.00062697 |
86 | Cortical dysplasia (HP:0002539) | 1.97604754 |
87 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.96464690 |
88 | Wrist flexion contracture (HP:0001239) | 1.96440314 |
89 | Disproportionate tall stature (HP:0001519) | 1.96069299 |
90 | Partial duplication of thumb phalanx (HP:0009944) | 1.94903415 |
91 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.94893192 |
92 | Shawl scrotum (HP:0000049) | 1.94278489 |
93 | Broad phalanges of the hand (HP:0009768) | 1.94019411 |
94 | Bronchomalacia (HP:0002780) | 1.93876595 |
95 | Ectopic kidney (HP:0000086) | 1.93757028 |
96 | Mitral valve prolapse (HP:0001634) | 1.91790841 |
97 | Abnormality of the parathyroid morphology (HP:0011766) | 1.91462690 |
98 | Medulloblastoma (HP:0002885) | 1.91435060 |
99 | Intestinal polyp (HP:0005266) | 1.91366858 |
100 | Fibroma (HP:0010614) | 1.91297783 |
101 | Reticulocytopenia (HP:0001896) | 1.91111680 |
102 | Venous insufficiency (HP:0005293) | 1.91104414 |
103 | Chromsome breakage (HP:0040012) | 1.90198469 |
104 | Follicular hyperkeratosis (HP:0007502) | 1.89875933 |
105 | Syncope (HP:0001279) | 1.89126312 |
106 | Spastic diplegia (HP:0001264) | 1.88800123 |
107 | Abnormality of the fingertips (HP:0001211) | 1.88697876 |
108 | Prolonged QT interval (HP:0001657) | 1.88455416 |
109 | Esophageal atresia (HP:0002032) | 1.87434894 |
110 | Short palpebral fissure (HP:0012745) | 1.86899031 |
111 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.85718431 |
112 | Aplasia of the phalanges of the hand (HP:0009802) | 1.85718431 |
113 | Aplasia involving bones of the extremities (HP:0009825) | 1.85718431 |
114 | Long palpebral fissure (HP:0000637) | 1.85699531 |
115 | Myotonia (HP:0002486) | 1.85620290 |
116 | Fibrous tissue neoplasm (HP:0012316) | 1.85305586 |
117 | Sprengel anomaly (HP:0000912) | 1.84563027 |
118 | Selective tooth agenesis (HP:0001592) | 1.84194342 |
119 | Broad finger (HP:0001500) | 1.84168598 |
120 | Metaphyseal cupping (HP:0003021) | 1.83680428 |
121 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.82724920 |
122 | Patellar aplasia (HP:0006443) | 1.82492198 |
123 | Ventricular fibrillation (HP:0001663) | 1.82367769 |
124 | Deformed tarsal bones (HP:0008119) | 1.81839360 |
125 | Absent radius (HP:0003974) | 1.81566233 |
126 | Skin pits (HP:0100276) | 1.81060921 |
127 | Long eyelashes (HP:0000527) | 1.80998911 |
128 | Spina bifida occulta (HP:0003298) | 1.80977075 |
129 | Overgrowth (HP:0001548) | 1.80347251 |
130 | Deviation of the hallux (HP:0010051) | 1.79824994 |
131 | Calf muscle hypertrophy (HP:0008981) | 1.79633901 |
132 | Abnormality of the sella turcica (HP:0002679) | 1.79142045 |
133 | Ankyloglossia (HP:0010296) | 1.78083687 |
134 | Rectal prolapse (HP:0002035) | 1.77529992 |
135 | Hallux valgus (HP:0001822) | 1.76445338 |
136 | Exercise-induced myalgia (HP:0003738) | 1.75749078 |
137 | Hypercalcemia (HP:0003072) | 1.75502544 |
138 | Venous abnormality (HP:0002624) | 1.75202482 |
139 | Intestinal fistula (HP:0100819) | 1.75027549 |
140 | Pointed chin (HP:0000307) | 1.74227507 |
141 | Coronal craniosynostosis (HP:0004440) | 1.73030395 |
142 | Generalized hypotonia (HP:0001290) | 1.70872671 |
143 | Bundle branch block (HP:0011710) | 1.67824390 |
144 | Arnold-Chiari malformation (HP:0002308) | 1.67612485 |
145 | Adducted thumb (HP:0001181) | 1.67119719 |
146 | Breast hypoplasia (HP:0003187) | 1.67115997 |
147 | Hypoventilation (HP:0002791) | 1.66377118 |
148 | Gastrointestinal carcinoma (HP:0002672) | 1.65987454 |
149 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.65987454 |
150 | Hip contracture (HP:0003273) | 1.65459679 |
151 | Partial agenesis of the corpus callosum (HP:0001338) | 1.65330048 |
152 | Aplasia involving forearm bones (HP:0009822) | 1.64217770 |
153 | Absent forearm bone (HP:0003953) | 1.64217770 |
154 | Hamartoma (HP:0010566) | 1.63839349 |
155 | Abnormality of the nasolacrimal system (HP:0000614) | 1.63839169 |
156 | Birth length less than 3rd percentile (HP:0003561) | 1.63050982 |
157 | Scapular winging (HP:0003691) | 1.62236781 |
158 | Limb-girdle muscle weakness (HP:0003325) | 1.62219747 |
159 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.61860202 |
160 | Atrioventricular block (HP:0001678) | 1.61403291 |
161 | Facial cleft (HP:0002006) | 1.61063356 |
162 | Capillary hemangiomas (HP:0005306) | 1.61012693 |
163 | Neonatal death (HP:0003811) | 1.60960443 |
164 | Abnormal ventriculo-arterial connection (HP:0011563) | 1.60924973 |
165 | Transposition of the great arteries (HP:0001669) | 1.60924973 |
166 | Abnormal connection of the cardiac segments (HP:0011545) | 1.60924973 |
167 | Pulmonary artery stenosis (HP:0004415) | 1.60236884 |
168 | Annular pancreas (HP:0001734) | 1.59736415 |
169 | Anal stenosis (HP:0002025) | 1.59669826 |
170 | Proximal placement of thumb (HP:0009623) | 1.59253541 |
171 | Deviation of the thumb (HP:0009603) | 1.59124452 |
172 | Vaginal fistula (HP:0004320) | 1.58841800 |
173 | Precocious puberty (HP:0000826) | 1.58737240 |
174 | Abdominal situs inversus (HP:0003363) | 1.58727445 |
175 | Abnormality of abdominal situs (HP:0011620) | 1.58727445 |
176 | Broad phalanx (HP:0006009) | 1.58692905 |
177 | Thin ribs (HP:0000883) | 1.57566918 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TIE1 | 5.21535263 |
2 | EPHB2 | 3.98061753 |
3 | PKN2 | 3.50748802 |
4 | SMG1 | 3.50618699 |
5 | TRIB3 | 3.47121853 |
6 | CDC7 | 2.86466343 |
7 | RIPK1 | 2.73158637 |
8 | KDR | 2.61794348 |
9 | TTN | 2.61325717 |
10 | MAP3K10 | 2.48912335 |
11 | PDGFRA | 2.11337448 |
12 | ICK | 2.04995119 |
13 | LATS2 | 1.90464206 |
14 | PLK4 | 1.87436486 |
15 | TTK | 1.83499448 |
16 | PTK6 | 1.80874183 |
17 | PHKG2 | 1.80616421 |
18 | PHKG1 | 1.80616421 |
19 | CDK12 | 1.78411515 |
20 | EEF2K | 1.64823982 |
21 | MARK1 | 1.63376991 |
22 | LMTK2 | 1.61838540 |
23 | TGFBR1 | 1.60037682 |
24 | TAF1 | 1.59770231 |
25 | TYRO3 | 1.56640021 |
26 | LATS1 | 1.54182239 |
27 | DMPK | 1.54025526 |
28 | SIK2 | 1.45391704 |
29 | FER | 1.37813754 |
30 | CHEK2 | 1.34128524 |
31 | SIK1 | 1.33122008 |
32 | PRKD3 | 1.32990520 |
33 | PRPF4B | 1.26108345 |
34 | FGFR4 | 1.25934184 |
35 | DDR2 | 1.23997125 |
36 | SRPK1 | 1.20696645 |
37 | BUB1 | 1.20681988 |
38 | TGFBR2 | 1.14474806 |
39 | MTOR | 1.14091353 |
40 | PTK2 | 1.10723526 |
41 | PAK4 | 1.08442408 |
42 | DYRK3 | 1.08435075 |
43 | CDK7 | 1.07351952 |
44 | VRK2 | 1.05289727 |
45 | PBK | 1.02801403 |
46 | CDC42BPA | 1.02068261 |
47 | RET | 1.00141393 |
48 | ILK | 0.99634524 |
49 | STK4 | 0.99387345 |
50 | ATR | 0.98279541 |
51 | RPS6KB2 | 0.96031113 |
52 | MYLK | 0.95799721 |
53 | FGFR1 | 0.95751046 |
54 | CAMK1G | 0.95238367 |
55 | FGFR2 | 0.93831317 |
56 | ZAK | 0.93467666 |
57 | NEK1 | 0.92541832 |
58 | AURKA | 0.91545664 |
59 | PTK2B | 0.90823304 |
60 | CHEK1 | 0.88056186 |
61 | PRKD1 | 0.87371632 |
62 | NEK2 | 0.86702560 |
63 | ALK | 0.85170786 |
64 | ROCK1 | 0.82335414 |
65 | NME2 | 0.82238573 |
66 | EIF2AK1 | 0.81116334 |
67 | PLK1 | 0.80387407 |
68 | INSRR | 0.80106943 |
69 | PAK2 | 0.79660588 |
70 | CAMK4 | 0.79019827 |
71 | CAMK1D | 0.78493943 |
72 | PDGFRB | 0.74234141 |
73 | ERBB2 | 0.70792255 |
74 | NME1 | 0.70725634 |
75 | CDK2 | 0.69941813 |
76 | BMX | 0.69674560 |
77 | BRAF | 0.68883875 |
78 | PAK3 | 0.68278009 |
79 | DYRK2 | 0.67937420 |
80 | PRKCI | 0.67862708 |
81 | TSSK6 | 0.67517862 |
82 | PASK | 0.67111935 |
83 | AURKB | 0.64102680 |
84 | MAP3K9 | 0.64020056 |
85 | CDK1 | 0.63303502 |
86 | CDK19 | 0.62109623 |
87 | UHMK1 | 0.61674439 |
88 | RPS6KA6 | 0.61314754 |
89 | MET | 0.60569693 |
90 | AKT2 | 0.59515906 |
91 | MAP2K2 | 0.59266004 |
92 | MKNK2 | 0.58860215 |
93 | BRD4 | 0.57450510 |
94 | MAP3K8 | 0.56160870 |
95 | ATM | 0.55886025 |
96 | CSNK1A1L | 0.55780304 |
97 | OBSCN | 0.55395593 |
98 | KSR1 | 0.54195650 |
99 | PIM1 | 0.54184782 |
100 | CASK | 0.54069566 |
101 | PAK6 | 0.54066264 |
102 | ROCK2 | 0.51640364 |
103 | LRRK2 | 0.51610253 |
104 | PLK3 | 0.51339636 |
105 | DAPK2 | 0.51287370 |
106 | NTRK2 | 0.51092949 |
107 | MAP3K7 | 0.50829197 |
108 | MAP3K4 | 0.50195547 |
109 | DAPK3 | 0.50153672 |
110 | EPHB1 | 0.50096163 |
111 | MKNK1 | 0.49825681 |
112 | BRSK1 | 0.48781526 |
113 | CDK6 | 0.48507163 |
114 | RPS6KA1 | 0.47649632 |
115 | RPS6KA5 | 0.47519056 |
116 | RPS6KA2 | 0.46319088 |
117 | CLK1 | 0.45864711 |
118 | GSK3A | 0.45101455 |
119 | TAOK1 | 0.44058564 |
120 | MARK2 | 0.43976208 |
121 | PRKDC | 0.43924145 |
122 | GSK3B | 0.43901753 |
123 | NTRK1 | 0.42848296 |
124 | RPS6KC1 | 0.42590664 |
125 | RPS6KL1 | 0.42590664 |
126 | TLK1 | 0.41601595 |
127 | MAP3K6 | 0.41562015 |
128 | CDK11A | 0.40574204 |
129 | CDK4 | 0.40275893 |
130 | PDK3 | 0.39615796 |
131 | PDK4 | 0.39615796 |
132 | MAPK14 | 0.39022949 |
133 | PRKAA1 | 0.38912454 |
134 | STK11 | 0.38154586 |
135 | PRKG2 | 0.37506560 |
136 | CDK15 | 0.37300820 |
137 | MAPK8 | 0.36988880 |
138 | DYRK1B | 0.36631803 |
139 | SCYL2 | 0.35485215 |
140 | SRC | 0.35437609 |
141 | MAPK9 | 0.34216972 |
142 | AKT1 | 0.33953045 |
143 | CSNK1G3 | 0.32725668 |
144 | PNCK | 0.32239964 |
145 | CSNK1G1 | 0.31403263 |
146 | CSNK1D | 0.30773641 |
147 | CSNK1E | 0.30707813 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Basal cell carcinoma_Homo sapiens_hsa05217 | 3.77782470 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.36540740 |
3 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 2.94814457 |
4 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.53836499 |
5 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.47371856 |
6 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.32237550 |
7 | Notch signaling pathway_Homo sapiens_hsa04330 | 2.29461520 |
8 | Cell cycle_Homo sapiens_hsa04110 | 2.24654122 |
9 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.15897343 |
10 | Hippo signaling pathway_Homo sapiens_hsa04390 | 2.08805112 |
11 | Axon guidance_Homo sapiens_hsa04360 | 2.06109981 |
12 | Mismatch repair_Homo sapiens_hsa03430 | 2.04030215 |
13 | Focal adhesion_Homo sapiens_hsa04510 | 2.01091809 |
14 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.96616607 |
15 | Base excision repair_Homo sapiens_hsa03410 | 1.93183099 |
16 | Spliceosome_Homo sapiens_hsa03040 | 1.92523049 |
17 | Adherens junction_Homo sapiens_hsa04520 | 1.91386198 |
18 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.91187186 |
19 | Viral myocarditis_Homo sapiens_hsa05416 | 1.72277803 |
20 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.69645779 |
21 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.66427382 |
22 | RNA transport_Homo sapiens_hsa03013 | 1.65892866 |
23 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.64343592 |
24 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.62551097 |
25 | Tight junction_Homo sapiens_hsa04530 | 1.60642722 |
26 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.59687295 |
27 | Melanogenesis_Homo sapiens_hsa04916 | 1.59581695 |
28 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.56950116 |
29 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.55014671 |
30 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.50872709 |
31 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.45997417 |
32 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.39813950 |
33 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.39060313 |
34 | Lysine degradation_Homo sapiens_hsa00310 | 1.37771262 |
35 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.37196773 |
36 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.36479934 |
37 | Amoebiasis_Homo sapiens_hsa05146 | 1.36463469 |
38 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.34584853 |
39 | Ribosome_Homo sapiens_hsa03010 | 1.32472404 |
40 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.32335594 |
41 | Endometrial cancer_Homo sapiens_hsa05213 | 1.31025908 |
42 | Pathways in cancer_Homo sapiens_hsa05200 | 1.29527134 |
43 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.27375492 |
44 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.24879264 |
45 | Sulfur relay system_Homo sapiens_hsa04122 | 1.24569769 |
46 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.20050940 |
47 | Thyroid cancer_Homo sapiens_hsa05216 | 1.17611412 |
48 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.16751512 |
49 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.16143006 |
50 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.14991451 |
51 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.12999425 |
52 | Gap junction_Homo sapiens_hsa04540 | 1.12390903 |
53 | Insulin resistance_Homo sapiens_hsa04931 | 1.12321361 |
54 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.10190916 |
55 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.08755521 |
56 | Colorectal cancer_Homo sapiens_hsa05210 | 1.07432700 |
57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.02878058 |
58 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.02188655 |
59 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.01194038 |
60 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.00790196 |
61 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.99669624 |
62 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.98236532 |
63 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.96417573 |
64 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.96284337 |
65 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.96123663 |
66 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.92292560 |
67 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.89761864 |
68 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.88988556 |
69 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.88890523 |
70 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.87621958 |
71 | Glioma_Homo sapiens_hsa05214 | 0.86219180 |
72 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.85488102 |
73 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.85132785 |
74 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.85055189 |
75 | Renin secretion_Homo sapiens_hsa04924 | 0.83692396 |
76 | HTLV-I infection_Homo sapiens_hsa05166 | 0.83640808 |
77 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.82228504 |
78 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.80947737 |
79 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.80941323 |
80 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.80641361 |
81 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.80615176 |
82 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.79850382 |
83 | Homologous recombination_Homo sapiens_hsa03440 | 0.79789579 |
84 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.79168495 |
85 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.78088665 |
86 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.77955955 |
87 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.77897628 |
88 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.77170465 |
89 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.76300523 |
90 | Bladder cancer_Homo sapiens_hsa05219 | 0.76032000 |
91 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.75166958 |
92 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.74724863 |
93 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.73557981 |
94 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.72855860 |
95 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.71827298 |
96 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.71579437 |
97 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.71416283 |
98 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.71265373 |
99 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.67565515 |
100 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.67358631 |
101 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.65862224 |
102 | Melanoma_Homo sapiens_hsa05218 | 0.65112664 |
103 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.64722446 |
104 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.63569856 |
105 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.62791810 |
106 | Platelet activation_Homo sapiens_hsa04611 | 0.62563693 |
107 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.62435839 |
108 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.61655890 |
109 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.61422901 |
110 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.60845149 |
111 | Prostate cancer_Homo sapiens_hsa05215 | 0.58925624 |
112 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.58893040 |
113 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.58800486 |
114 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.58554523 |
115 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.57651640 |
116 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56498372 |
117 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.56488404 |
118 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.56448593 |
119 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.56116501 |
120 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.54630108 |
121 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.54506912 |
122 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.54219171 |
123 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.53534070 |
124 | Circadian entrainment_Homo sapiens_hsa04713 | 0.50141342 |
125 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.49924482 |
126 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.49326269 |
127 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.49125272 |
128 | RNA polymerase_Homo sapiens_hsa03020 | 0.48471233 |
129 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.47796977 |
130 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.47519149 |
131 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.46955833 |
132 | Galactose metabolism_Homo sapiens_hsa00052 | 0.46690979 |
133 | Carbon metabolism_Homo sapiens_hsa01200 | 0.44593365 |
134 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.44074416 |
135 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.43569448 |
136 | Alcoholism_Homo sapiens_hsa05034 | 0.42685793 |
137 | Purine metabolism_Homo sapiens_hsa00230 | 0.42621834 |
138 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.40793630 |
139 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.39241703 |