

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 8.11580656 |
| 2 | thrombin receptor signaling pathway (GO:0070493) | 7.45893389 |
| 3 | neutrophil activation involved in immune response (GO:0002283) | 6.90497660 |
| 4 | blood coagulation, intrinsic pathway (GO:0007597) | 5.93089208 |
| 5 | regulation of platelet aggregation (GO:0090330) | 5.85888447 |
| 6 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 5.84917532 |
| 7 | adenosine receptor signaling pathway (GO:0001973) | 5.52637506 |
| 8 | regulation of platelet activation (GO:0010543) | 5.49597663 |
| 9 | negative regulation of norepinephrine secretion (GO:0010700) | 5.29705137 |
| 10 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 5.07332921 |
| 11 | platelet aggregation (GO:0070527) | 4.99530862 |
| 12 | leukocyte migration involved in inflammatory response (GO:0002523) | 4.97666205 |
| 13 | regulation of integrin-mediated signaling pathway (GO:2001044) | 4.94805236 |
| 14 | low-density lipoprotein particle remodeling (GO:0034374) | 4.77940310 |
| 15 | negative regulation of platelet activation (GO:0010544) | 4.70886863 |
| 16 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 4.63447766 |
| 17 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 4.60310456 |
| 18 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 4.58357470 |
| 19 | negative regulation of thymocyte apoptotic process (GO:0070244) | 4.47534487 |
| 20 | positive regulation of endothelial cell differentiation (GO:0045603) | 4.36823281 |
| 21 | regulation of lipoprotein metabolic process (GO:0050746) | 4.25808345 |
| 22 | negative regulation of heart rate (GO:0010459) | 4.24016257 |
| 23 | angiogenesis involved in wound healing (GO:0060055) | 4.13662324 |
| 24 | positive regulation of mast cell activation (GO:0033005) | 3.95774506 |
| 25 | negative regulation of protein localization to cell surface (GO:2000009) | 3.95138735 |
| 26 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.94886014 |
| 27 | neutrophil activation (GO:0042119) | 3.92418002 |
| 28 | negative regulation of response to food (GO:0032096) | 3.92154643 |
| 29 | negative regulation of appetite (GO:0032099) | 3.92154643 |
| 30 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 3.89618041 |
| 31 | lipoxygenase pathway (GO:0019372) | 3.88063063 |
| 32 | platelet degranulation (GO:0002576) | 3.87703821 |
| 33 | megakaryocyte development (GO:0035855) | 3.84277664 |
| 34 | purinergic receptor signaling pathway (GO:0035587) | 3.79318906 |
| 35 | high-density lipoprotein particle remodeling (GO:0034375) | 3.77818815 |
| 36 | G-protein coupled purinergic receptor signaling pathway (GO:0035588) | 3.68212171 |
| 37 | regulation of integrin activation (GO:0033623) | 3.66351798 |
| 38 | beta-amyloid metabolic process (GO:0050435) | 3.65380657 |
| 39 | regulation of norepinephrine secretion (GO:0014061) | 3.61815394 |
| 40 | platelet activation (GO:0030168) | 3.59517484 |
| 41 | polyamine biosynthetic process (GO:0006596) | 3.58681222 |
| 42 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.57836110 |
| 43 | platelet formation (GO:0030220) | 3.56063597 |
| 44 | reverse cholesterol transport (GO:0043691) | 3.54019761 |
| 45 | positive regulation of macrophage differentiation (GO:0045651) | 3.53878953 |
| 46 | positive regulation of blood coagulation (GO:0030194) | 3.53137773 |
| 47 | positive regulation of hemostasis (GO:1900048) | 3.53137773 |
| 48 | positive regulation of systemic arterial blood pressure (GO:0003084) | 3.52994733 |
| 49 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.52315613 |
| 50 | positive regulation of granulocyte differentiation (GO:0030854) | 3.44918268 |
| 51 | positive regulation of Rho protein signal transduction (GO:0035025) | 3.43622668 |
| 52 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 3.40277324 |
| 53 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.40052518 |
| 54 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.40052518 |
| 55 | relaxation of smooth muscle (GO:0044557) | 3.37583431 |
| 56 | granulocyte activation (GO:0036230) | 3.36035079 |
| 57 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.35822234 |
| 58 | L-phenylalanine catabolic process (GO:0006559) | 3.35822234 |
| 59 | homotypic cell-cell adhesion (GO:0034109) | 3.35577533 |
| 60 | regulation of female receptivity (GO:0045924) | 3.29673626 |
| 61 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.29590496 |
| 62 | negative regulation of catecholamine secretion (GO:0033604) | 3.29356047 |
| 63 | regulation of homotypic cell-cell adhesion (GO:0034110) | 3.28248899 |
| 64 | negative regulation of neural precursor cell proliferation (GO:2000178) | 3.26409766 |
| 65 | termination of G-protein coupled receptor signaling pathway (GO:0038032) | 3.23728793 |
| 66 | phospholipid homeostasis (GO:0055091) | 3.20278325 |
| 67 | autophagic vacuole fusion (GO:0000046) | 3.16271388 |
| 68 | positive regulation of receptor recycling (GO:0001921) | 3.12774545 |
| 69 | negative regulation of heart contraction (GO:0045822) | 3.12441721 |
| 70 | positive regulation of coagulation (GO:0050820) | 3.09559466 |
| 71 | termination of signal transduction (GO:0023021) | 3.08755436 |
| 72 | leukocyte degranulation (GO:0043299) | 3.06421163 |
| 73 | regulation of hemostasis (GO:1900046) | 3.05906971 |
| 74 | regulation of blood coagulation (GO:0030193) | 3.05906971 |
| 75 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.04168142 |
| 76 | negative regulation of T cell apoptotic process (GO:0070233) | 3.01456897 |
| 77 | positive regulation of protein homodimerization activity (GO:0090073) | 3.01197841 |
| 78 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 2.98605080 |
| 79 | negative regulation of interleukin-17 production (GO:0032700) | 2.94096885 |
| 80 | regulation of memory T cell differentiation (GO:0043380) | 2.93559068 |
| 81 | extracellular fibril organization (GO:0043206) | 2.92164463 |
| 82 | endothelium development (GO:0003158) | 2.90902666 |
| 83 | regulation of endothelial cell differentiation (GO:0045601) | 2.89270319 |
| 84 | negative regulation of blood coagulation (GO:0030195) | 2.88782543 |
| 85 | negative regulation of hemostasis (GO:1900047) | 2.88782543 |
| 86 | female mating behavior (GO:0060180) | 2.86910549 |
| 87 | positive regulation of muscle hypertrophy (GO:0014742) | 2.86691534 |
| 88 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 2.86691534 |
| 89 | plasma membrane fusion (GO:0045026) | 2.86071701 |
| 90 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.83263813 |
| 91 | tyrosine metabolic process (GO:0006570) | 2.82229164 |
| 92 | fatty acid elongation (GO:0030497) | 2.81574741 |
| 93 | regulation of mast cell activation (GO:0033003) | 2.81277590 |
| 94 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.79310946 |
| 95 | regulation of coagulation (GO:0050818) | 2.74879714 |
| 96 | monoamine transport (GO:0015844) | 2.74591734 |
| 97 | regulation of megakaryocyte differentiation (GO:0045652) | 2.71270765 |
| 98 | regulation of cholesterol efflux (GO:0010874) | 2.70757255 |
| 99 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.70528988 |
| 100 | phagocytosis, engulfment (GO:0006911) | 2.69087416 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 4.65992314 |
| 2 | SCL_19346495_ChIP-Seq_HPC-7_Human | 3.95348091 |
| 3 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 3.84740864 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.24631156 |
| 5 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 3.02958505 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.91008452 |
| 7 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.59929977 |
| 8 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.59913101 |
| 9 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.59261932 |
| 10 | GATA1_19941826_ChIP-Seq_K562_Human | 2.52080279 |
| 11 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 2.47419577 |
| 12 | GATA2_19941826_ChIP-Seq_K562_Human | 2.27782423 |
| 13 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.25614082 |
| 14 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 2.23038432 |
| 15 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.22785192 |
| 16 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 2.14518839 |
| 17 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.13918518 |
| 18 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.13159693 |
| 19 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.09003162 |
| 20 | SPI1_23127762_ChIP-Seq_K562_Human | 2.05258876 |
| 21 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.87361753 |
| 22 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.83165806 |
| 23 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.77543183 |
| 24 | GATA1_22025678_ChIP-Seq_K562_Human | 1.76498357 |
| 25 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.75144896 |
| 26 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.74748249 |
| 27 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.73822145 |
| 28 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 1.69050861 |
| 29 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.65788031 |
| 30 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.64413047 |
| 31 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.63522144 |
| 32 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.61315590 |
| 33 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.54818426 |
| 34 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.54005401 |
| 35 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.43104161 |
| 36 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.38153130 |
| 37 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.36984410 |
| 38 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.35562216 |
| 39 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.35562216 |
| 40 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.32554465 |
| 41 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.31470094 |
| 42 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.31054753 |
| 43 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.29223397 |
| 44 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.28636181 |
| 45 | VDR_22108803_ChIP-Seq_LS180_Human | 1.28459965 |
| 46 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.26476442 |
| 47 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.24578446 |
| 48 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.22022325 |
| 49 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.20557615 |
| 50 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.20438672 |
| 51 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.18592946 |
| 52 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.16465073 |
| 53 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.14937828 |
| 54 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.14576275 |
| 55 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13398367 |
| 56 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10772106 |
| 57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.09973031 |
| 58 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.07727239 |
| 59 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.06847581 |
| 60 | AR_25329375_ChIP-Seq_VCAP_Human | 1.05153346 |
| 61 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.04865400 |
| 62 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.04797077 |
| 63 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.02915276 |
| 64 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 1.01943859 |
| 65 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.01554261 |
| 66 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.01090331 |
| 67 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.99827016 |
| 68 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.97362375 |
| 69 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.96519554 |
| 70 | LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.96278997 |
| 71 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.93861368 |
| 72 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.93606450 |
| 73 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.93512089 |
| 74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.93229582 |
| 75 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.92463747 |
| 76 | P300_19829295_ChIP-Seq_ESCs_Human | 0.91686387 |
| 77 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.90464814 |
| 78 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.90372121 |
| 79 | STAT3_23295773_ChIP-Seq_U87_Human | 0.89882695 |
| 80 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.89646859 |
| 81 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.88262079 |
| 82 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.86980874 |
| 83 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.86819096 |
| 84 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.86484995 |
| 85 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.86459092 |
| 86 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.83709977 |
| 87 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.83709977 |
| 88 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.83319406 |
| 89 | TCF4_23295773_ChIP-Seq_U87_Human | 0.82755125 |
| 90 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.81532991 |
| 91 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.80016992 |
| 92 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.80016992 |
| 93 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.79160263 |
| 94 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.78880794 |
| 95 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.78744875 |
| 96 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.78699689 |
| 97 | TBL1_22424771_ChIP-Seq_293T_Human | 0.78075560 |
| 98 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.77929262 |
| 99 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.77449743 |
| 100 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.77265762 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005464_abnormal_platelet_physiology | 9.65948089 |
| 2 | MP0008004_abnormal_stomach_pH | 5.74006490 |
| 3 | MP0003724_increased_susceptibility_to | 3.43042797 |
| 4 | MP0000465_gastrointestinal_hemorrhage | 3.32450078 |
| 5 | MP0004084_abnormal_cardiac_muscle | 2.53391795 |
| 6 | MP0004510_myositis | 2.45058189 |
| 7 | MP0005084_abnormal_gallbladder_morpholo | 2.32518150 |
| 8 | MP0000230_abnormal_systemic_arterial | 2.22734035 |
| 9 | MP0001835_abnormal_antigen_presentation | 2.20257826 |
| 10 | MP0000343_altered_response_to | 2.17046669 |
| 11 | MP0005410_abnormal_fertilization | 2.09068572 |
| 12 | MP0002736_abnormal_nociception_after | 2.07556970 |
| 13 | MP0005083_abnormal_biliary_tract | 1.97103080 |
| 14 | MP0005646_abnormal_pituitary_gland | 1.87983360 |
| 15 | MP0002132_abnormal_respiratory_system | 1.85451720 |
| 16 | MP0008872_abnormal_physiological_respon | 1.81436752 |
| 17 | MP0004036_abnormal_muscle_relaxation | 1.80513567 |
| 18 | MP0008775_abnormal_heart_ventricle | 1.78875198 |
| 19 | MP0005058_abnormal_lysosome_morphology | 1.78863434 |
| 20 | MP0003303_peritoneal_inflammation | 1.75627332 |
| 21 | MP0001879_abnormal_lymphatic_vessel | 1.69356069 |
| 22 | MP0001545_abnormal_hematopoietic_system | 1.69141482 |
| 23 | MP0005397_hematopoietic_system_phenotyp | 1.69141482 |
| 24 | MP0003638_abnormal_response/metabolism_ | 1.67301347 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.64941005 |
| 26 | MP0003879_abnormal_hair_cell | 1.61197807 |
| 27 | MP0003828_pulmonary_edema | 1.59785442 |
| 28 | MP0004130_abnormal_muscle_cell | 1.58668889 |
| 29 | MP0005167_abnormal_blood-brain_barrier | 1.53352784 |
| 30 | MP0010329_abnormal_lipoprotein_level | 1.52037838 |
| 31 | MP0010155_abnormal_intestine_physiology | 1.50865907 |
| 32 | MP0003566_abnormal_cell_adhesion | 1.46315772 |
| 33 | MP0009697_abnormal_copulation | 1.39092297 |
| 34 | MP0002148_abnormal_hypersensitivity_rea | 1.39066043 |
| 35 | MP0003136_yellow_coat_color | 1.35975416 |
| 36 | MP0002733_abnormal_thermal_nociception | 1.35441766 |
| 37 | MP0001851_eye_inflammation | 1.30984434 |
| 38 | MP0002398_abnormal_bone_marrow | 1.30505067 |
| 39 | MP0006276_abnormal_autonomic_nervous | 1.29902256 |
| 40 | MP0000249_abnormal_blood_vessel | 1.29540243 |
| 41 | MP0009780_abnormal_chondrocyte_physiolo | 1.25554367 |
| 42 | MP0005000_abnormal_immune_tolerance | 1.24294417 |
| 43 | MP0005671_abnormal_response_to | 1.20628875 |
| 44 | MP0001663_abnormal_digestive_system | 1.18233727 |
| 45 | MP0003656_abnormal_erythrocyte_physiolo | 1.08455303 |
| 46 | MP0004215_abnormal_myocardial_fiber | 1.07944340 |
| 47 | MP0001664_abnormal_digestion | 1.07209148 |
| 48 | MP0010368_abnormal_lymphatic_system | 1.06280195 |
| 49 | MP0009763_increased_sensitivity_to | 1.05450386 |
| 50 | MP0009642_abnormal_blood_homeostasis | 1.01950422 |
| 51 | MP0010386_abnormal_urinary_bladder | 0.99234819 |
| 52 | MP0009278_abnormal_bone_marrow | 0.96850543 |
| 53 | MP0001970_abnormal_pain_threshold | 0.95867396 |
| 54 | MP0000689_abnormal_spleen_morphology | 0.95829708 |
| 55 | MP0002723_abnormal_immune_serum | 0.95289378 |
| 56 | MP0000858_altered_metastatic_potential | 0.93654638 |
| 57 | MP0004484_altered_response_of | 0.93483278 |
| 58 | MP0008874_decreased_physiological_sensi | 0.93396200 |
| 59 | MP0003183_abnormal_peptide_metabolism | 0.93394960 |
| 60 | MP0003436_decreased_susceptibility_to | 0.93141410 |
| 61 | MP0005409_darkened_coat_color | 0.93041526 |
| 62 | MP0004808_abnormal_hematopoietic_stem | 0.90504307 |
| 63 | MP0002429_abnormal_blood_cell | 0.88488175 |
| 64 | MP0001533_abnormal_skeleton_physiology | 0.87939398 |
| 65 | MP0005666_abnormal_adipose_tissue | 0.87173751 |
| 66 | MP0004134_abnormal_chest_morphology | 0.87117881 |
| 67 | MP0001800_abnormal_humoral_immune | 0.85172707 |
| 68 | MP0005174_abnormal_tail_pigmentation | 0.84993043 |
| 69 | MP0002735_abnormal_chemical_nociception | 0.83416194 |
| 70 | MP0000015_abnormal_ear_pigmentation | 0.83388775 |
| 71 | MP0002722_abnormal_immune_system | 0.82893456 |
| 72 | MP0004947_skin_inflammation | 0.79450696 |
| 73 | MP0002452_abnormal_antigen_presenting | 0.79192669 |
| 74 | MP0002972_abnormal_cardiac_muscle | 0.78810583 |
| 75 | MP0005385_cardiovascular_system_phenoty | 0.78484780 |
| 76 | MP0001544_abnormal_cardiovascular_syste | 0.78484780 |
| 77 | MP0009764_decreased_sensitivity_to | 0.77444092 |
| 78 | MP0009765_abnormal_xenobiotic_induced | 0.76849576 |
| 79 | MP0002118_abnormal_lipid_homeostasis | 0.76454064 |
| 80 | MP0006138_congestive_heart_failure | 0.76007617 |
| 81 | MP0001765_abnormal_ion_homeostasis | 0.75855334 |
| 82 | MP0005535_abnormal_body_temperature | 0.75814087 |
| 83 | MP0000716_abnormal_immune_system | 0.75468902 |
| 84 | MP0006036_abnormal_mitochondrial_physio | 0.75408294 |
| 85 | MP0002420_abnormal_adaptive_immunity | 0.75350168 |
| 86 | MP0005381_digestive/alimentary_phenotyp | 0.75142957 |
| 87 | MP0002419_abnormal_innate_immunity | 0.74628487 |
| 88 | MP0002128_abnormal_blood_circulation | 0.73703452 |
| 89 | MP0001819_abnormal_immune_cell | 0.73511383 |
| 90 | MP0003866_abnormal_defecation | 0.73066610 |
| 91 | MP0005365_abnormal_bile_salt | 0.71208181 |
| 92 | MP0001756_abnormal_urination | 0.70781444 |
| 93 | MP0000685_abnormal_immune_system | 0.70478096 |
| 94 | MP0001845_abnormal_inflammatory_respons | 0.70219483 |
| 95 | MP0005620_abnormal_muscle_contractility | 0.70092142 |
| 96 | MP0002876_abnormal_thyroid_physiology | 0.70049763 |
| 97 | MP0004085_abnormal_heartbeat | 0.69641151 |
| 98 | MP0005025_abnormal_response_to | 0.68309864 |
| 99 | MP0002998_abnormal_bone_remodeling | 0.65684573 |
| 100 | MP0006054_spinal_hemorrhage | 0.64025872 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal platelet volume (HP:0011876) | 9.45402110 |
| 2 | Petechiae (HP:0000967) | 9.27189186 |
| 3 | Purpura (HP:0000979) | 8.71912166 |
| 4 | Epistaxis (HP:0000421) | 7.95145366 |
| 5 | Gingival bleeding (HP:0000225) | 6.79758250 |
| 6 | Hyperlipoproteinemia (HP:0010980) | 6.18422055 |
| 7 | Abnormal platelet function (HP:0011869) | 5.83253015 |
| 8 | Impaired platelet aggregation (HP:0003540) | 5.83253015 |
| 9 | Dyschromatopsia (HP:0007641) | 4.77374073 |
| 10 | Spontaneous hematomas (HP:0007420) | 4.40266589 |
| 11 | Poikilocytosis (HP:0004447) | 4.23224714 |
| 12 | Acanthocytosis (HP:0001927) | 4.16226472 |
| 13 | Abnormality of the common coagulation pathway (HP:0010990) | 3.92541303 |
| 14 | Abnormality of lateral ventricle (HP:0030047) | 3.60209258 |
| 15 | Bruising susceptibility (HP:0000978) | 3.51031255 |
| 16 | Conjunctival telangiectasia (HP:0000524) | 3.47883300 |
| 17 | Abnormal pupillary function (HP:0007686) | 3.42607503 |
| 18 | Joint hemorrhage (HP:0005261) | 3.15670005 |
| 19 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.98190701 |
| 20 | Decreased central vision (HP:0007663) | 2.87922421 |
| 21 | Paralysis (HP:0003470) | 2.85901089 |
| 22 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.85426824 |
| 23 | Thyroid-stimulating hormone excess (HP:0002925) | 2.79269408 |
| 24 | Increased density of long bones (HP:0006392) | 2.75246908 |
| 25 | Xanthomatosis (HP:0000991) | 2.68879701 |
| 26 | Joint swelling (HP:0001386) | 2.55819638 |
| 27 | Spontaneous abortion (HP:0005268) | 2.51452652 |
| 28 | Abnormal auditory evoked potentials (HP:0006958) | 2.38345424 |
| 29 | Hepatosplenomegaly (HP:0001433) | 2.22547935 |
| 30 | Abnormal ciliary motility (HP:0012262) | 2.20102222 |
| 31 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.18829609 |
| 32 | Ventricular fibrillation (HP:0001663) | 2.12899276 |
| 33 | Abnormality of iron homeostasis (HP:0011031) | 2.11656038 |
| 34 | Hypophosphatemic rickets (HP:0004912) | 2.10829499 |
| 35 | Generalized aminoaciduria (HP:0002909) | 2.06331669 |
| 36 | Prolonged bleeding time (HP:0003010) | 11.7564341 |
| 37 | Menorrhagia (HP:0000132) | 10.6363366 |
| 38 | Increased mean platelet volume (HP:0011877) | 10.0310088 |
| 39 | Papillary thyroid carcinoma (HP:0002895) | 1.96494122 |
| 40 | Encephalitis (HP:0002383) | 1.94319622 |
| 41 | Biliary tract neoplasm (HP:0100574) | 1.92986889 |
| 42 | Stomatitis (HP:0010280) | 1.90504494 |
| 43 | Absent/shortened dynein arms (HP:0200106) | 1.89669133 |
| 44 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.89669133 |
| 45 | Thrombocytosis (HP:0001894) | 1.89044783 |
| 46 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.88433345 |
| 47 | Tinnitus (HP:0000360) | 1.88320418 |
| 48 | Episodic fever (HP:0001954) | 1.86593351 |
| 49 | Abnormality of the prostate (HP:0008775) | 1.86355125 |
| 50 | Upper limb muscle weakness (HP:0003484) | 1.85270994 |
| 51 | Panhypogammaglobulinemia (HP:0003139) | 1.84059225 |
| 52 | Male infertility (HP:0003251) | 1.83775905 |
| 53 | Hyperthyroidism (HP:0000836) | 1.81391036 |
| 54 | Abnormality of macrophages (HP:0004311) | 1.81051067 |
| 55 | Increased IgM level (HP:0003496) | 1.79532440 |
| 56 | Central scotoma (HP:0000603) | 1.78305701 |
| 57 | Arterial thrombosis (HP:0004420) | 1.75800003 |
| 58 | Nausea (HP:0002018) | 1.72388454 |
| 59 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.69687135 |
| 60 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.69687135 |
| 61 | Mitral stenosis (HP:0001718) | 1.67506233 |
| 62 | Polyphagia (HP:0002591) | 1.64967049 |
| 63 | Febrile seizures (HP:0002373) | 1.64902686 |
| 64 | Infertility (HP:0000789) | 1.63778605 |
| 65 | Arthropathy (HP:0003040) | 1.63041172 |
| 66 | Tongue fasciculations (HP:0001308) | 1.60355824 |
| 67 | Increased serum ferritin (HP:0003281) | 1.59034846 |
| 68 | Autoimmune hemolytic anemia (HP:0001890) | 1.57489824 |
| 69 | Chronic obstructive pulmonary disease (HP:0006510) | 1.56214674 |
| 70 | Obstructive lung disease (HP:0006536) | 1.56214674 |
| 71 | Testicular neoplasm (HP:0010788) | 1.54439406 |
| 72 | Polycythemia (HP:0001901) | 1.53653893 |
| 73 | Eosinophilia (HP:0001880) | 1.52225076 |
| 74 | Inflammation of the large intestine (HP:0002037) | 1.49660280 |
| 75 | Basal ganglia calcification (HP:0002135) | 1.49101614 |
| 76 | Muscle fiber splitting (HP:0003555) | 1.49067143 |
| 77 | Renal cortical cysts (HP:0000803) | 1.48962836 |
| 78 | Thrombophlebitis (HP:0004418) | 1.47948757 |
| 79 | Dysautonomia (HP:0002459) | 1.46763094 |
| 80 | Granulocytopenia (HP:0001913) | 1.43935573 |
| 81 | Diplopia (HP:0000651) | 1.43890822 |
| 82 | Abnormality of binocular vision (HP:0011514) | 1.43890822 |
| 83 | Muscle fibrillation (HP:0010546) | 1.43167992 |
| 84 | Visual hallucinations (HP:0002367) | 1.42569742 |
| 85 | Myocardial infarction (HP:0001658) | 1.41755855 |
| 86 | 3-Methylglutaconic aciduria (HP:0003535) | 1.40840774 |
| 87 | Vertigo (HP:0002321) | 1.40322044 |
| 88 | Congenital sensorineural hearing impairment (HP:0008527) | 1.39877442 |
| 89 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.39715486 |
| 90 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.38948903 |
| 91 | Gonadal dysgenesis (HP:0000133) | 1.38238251 |
| 92 | Chest pain (HP:0100749) | 1.36691328 |
| 93 | Gastrointestinal inflammation (HP:0004386) | 1.35670980 |
| 94 | Aortic aneurysm (HP:0004942) | 1.31843237 |
| 95 | Acute lymphatic leukemia (HP:0006721) | 1.31399786 |
| 96 | Clumsiness (HP:0002312) | 1.30894888 |
| 97 | Leiomyosarcoma (HP:0100243) | 1.29688824 |
| 98 | Uterine leiomyosarcoma (HP:0002891) | 1.29688824 |
| 99 | Hypomagnesemia (HP:0002917) | 1.28015643 |
| 100 | Leukocytosis (HP:0001974) | 1.25856952 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.59082147 |
| 2 | MYLK | 4.01754189 |
| 3 | MST4 | 4.00047666 |
| 4 | BMX | 3.86810135 |
| 5 | TEC | 3.19146857 |
| 6 | BTK | 3.08329389 |
| 7 | PTK2B | 2.72300774 |
| 8 | TAOK3 | 2.50540092 |
| 9 | CSF1R | 2.44298128 |
| 10 | SYK | 2.32146494 |
| 11 | EIF2AK1 | 2.31949864 |
| 12 | PIK3CG | 2.31045436 |
| 13 | ZAP70 | 1.88985317 |
| 14 | GRK6 | 1.87812133 |
| 15 | GRK5 | 1.86199400 |
| 16 | ILK | 1.81180048 |
| 17 | STK3 | 1.80574957 |
| 18 | ADRBK2 | 1.69803580 |
| 19 | MAPKAPK3 | 1.64385006 |
| 20 | FES | 1.63145192 |
| 21 | TNK2 | 1.58930522 |
| 22 | MARK3 | 1.57697477 |
| 23 | BMPR2 | 1.56081098 |
| 24 | FGR | 1.47513857 |
| 25 | HCK | 1.47161670 |
| 26 | PNCK | 1.34665376 |
| 27 | PLK2 | 1.31096141 |
| 28 | BMPR1B | 1.24561245 |
| 29 | TNIK | 1.18293704 |
| 30 | LYN | 1.06787321 |
| 31 | DAPK3 | 1.06364929 |
| 32 | PINK1 | 1.06359512 |
| 33 | PAK1 | 1.05365925 |
| 34 | NUAK1 | 1.04775686 |
| 35 | MAP3K5 | 0.99287371 |
| 36 | FLT3 | 0.99225016 |
| 37 | MAP2K3 | 0.98801605 |
| 38 | IKBKB | 0.98416895 |
| 39 | FRK | 0.95804215 |
| 40 | TRIM28 | 0.93638482 |
| 41 | DAPK2 | 0.92860393 |
| 42 | RET | 0.92646818 |
| 43 | BLK | 0.87580183 |
| 44 | MAPK12 | 0.87141913 |
| 45 | MAP4K2 | 0.86183313 |
| 46 | PDK1 | 0.83625330 |
| 47 | LMTK2 | 0.82975993 |
| 48 | ACVR1B | 0.80448415 |
| 49 | ITK | 0.79523694 |
| 50 | SGK2 | 0.77959880 |
| 51 | ADRBK1 | 0.76540605 |
| 52 | PKN1 | 0.75511471 |
| 53 | PRKD1 | 0.75467307 |
| 54 | MATK | 0.73343150 |
| 55 | IRAK1 | 0.71255913 |
| 56 | SIK3 | 0.70883372 |
| 57 | EPHA3 | 0.69508693 |
| 58 | MAPK13 | 0.69144777 |
| 59 | STK24 | 0.67019979 |
| 60 | PDPK1 | 0.66427344 |
| 61 | FER | 0.64657480 |
| 62 | TLK1 | 0.63685310 |
| 63 | NLK | 0.63451707 |
| 64 | GRK1 | 0.61403218 |
| 65 | CDK8 | 0.60864261 |
| 66 | PRKG1 | 0.60669701 |
| 67 | PRKCQ | 0.59872399 |
| 68 | KIT | 0.55893292 |
| 69 | PIM2 | 0.55671831 |
| 70 | PRKACG | 0.55465516 |
| 71 | INSRR | 0.54533785 |
| 72 | ERBB2 | 0.54491782 |
| 73 | TAOK2 | 0.51683663 |
| 74 | TXK | 0.48485880 |
| 75 | MINK1 | 0.46146053 |
| 76 | PDGFRB | 0.45442816 |
| 77 | LCK | 0.43982429 |
| 78 | PAK3 | 0.41116814 |
| 79 | DAPK1 | 0.39440015 |
| 80 | TAOK1 | 0.38968150 |
| 81 | CDK3 | 0.38076173 |
| 82 | PKN2 | 0.37595970 |
| 83 | MAP2K1 | 0.37446290 |
| 84 | STK4 | 0.36826330 |
| 85 | OBSCN | 0.35751816 |
| 86 | SGK494 | 0.34671028 |
| 87 | SGK223 | 0.34671028 |
| 88 | MAP3K3 | 0.34622431 |
| 89 | SGK3 | 0.34531055 |
| 90 | IGF1R | 0.34395287 |
| 91 | HIPK2 | 0.33574924 |
| 92 | ROCK1 | 0.33503077 |
| 93 | PRKCB | 0.33311957 |
| 94 | DYRK1A | 0.29585393 |
| 95 | FYN | 0.29403005 |
| 96 | CAMK1 | 0.28627141 |
| 97 | PRKCA | 0.28287439 |
| 98 | PRKCE | 0.27608819 |
| 99 | PAK2 | 0.26532875 |
| 100 | JAK2 | 0.24964609 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Platelet activation_Homo sapiens_hsa04611 | 5.55990561 |
| 2 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 3.34106494 |
| 3 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.90641617 |
| 4 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 2.75634760 |
| 5 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.43565212 |
| 6 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 2.16843566 |
| 7 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.07702766 |
| 8 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.06775560 |
| 9 | Gap junction_Homo sapiens_hsa04540 | 2.02262468 |
| 10 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.95788880 |
| 11 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.76430115 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.63889257 |
| 13 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.61819370 |
| 14 | Olfactory transduction_Homo sapiens_hsa04740 | 1.49566240 |
| 15 | Alcoholism_Homo sapiens_hsa05034 | 1.48053729 |
| 16 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.44100816 |
| 17 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.37827449 |
| 18 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.36590356 |
| 19 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.34055258 |
| 20 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.31200221 |
| 21 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.25592064 |
| 22 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.23283176 |
| 23 | Circadian entrainment_Homo sapiens_hsa04713 | 1.22934111 |
| 24 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.19925773 |
| 25 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.17523469 |
| 26 | Long-term depression_Homo sapiens_hsa04730 | 1.11051824 |
| 27 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.06135095 |
| 28 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.03498596 |
| 29 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.03141718 |
| 30 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 1.03063611 |
| 31 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.00072973 |
| 32 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.98489576 |
| 33 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.97404895 |
| 34 | Endocytosis_Homo sapiens_hsa04144 | 0.95590286 |
| 35 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.93296470 |
| 36 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.89040195 |
| 37 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.87988813 |
| 38 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.84855310 |
| 39 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.82369990 |
| 40 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.81316745 |
| 41 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.81051786 |
| 42 | Renin secretion_Homo sapiens_hsa04924 | 0.79944053 |
| 43 | Morphine addiction_Homo sapiens_hsa05032 | 0.79694334 |
| 44 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.78340106 |
| 45 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.77883084 |
| 46 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.76902568 |
| 47 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.76654819 |
| 48 | Focal adhesion_Homo sapiens_hsa04510 | 0.75927435 |
| 49 | Phototransduction_Homo sapiens_hsa04744 | 0.74022388 |
| 50 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.73298837 |
| 51 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.73148256 |
| 52 | Malaria_Homo sapiens_hsa05144 | 0.72376745 |
| 53 | GABAergic synapse_Homo sapiens_hsa04727 | 0.70956412 |
| 54 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.70919742 |
| 55 | Shigellosis_Homo sapiens_hsa05131 | 0.69869566 |
| 56 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.69691915 |
| 57 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.68325334 |
| 58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.66498702 |
| 59 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.66362789 |
| 60 | ABC transporters_Homo sapiens_hsa02010 | 0.66244936 |
| 61 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.66026946 |
| 62 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.64771677 |
| 63 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.63518715 |
| 64 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.63235288 |
| 65 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.63203504 |
| 66 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.62931332 |
| 67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.62204814 |
| 68 | Retinol metabolism_Homo sapiens_hsa00830 | 0.61976155 |
| 69 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.60481852 |
| 70 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.60448397 |
| 71 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.59728679 |
| 72 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.58003102 |
| 73 | Phagosome_Homo sapiens_hsa04145 | 0.57688258 |
| 74 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.57636498 |
| 75 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.57510584 |
| 76 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.57461741 |
| 77 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.57183177 |
| 78 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.54638675 |
| 79 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.52861467 |
| 80 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.51982318 |
| 81 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.51243936 |
| 82 | Melanoma_Homo sapiens_hsa05218 | 0.51169016 |
| 83 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.50930863 |
| 84 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.50843591 |
| 85 | Endometrial cancer_Homo sapiens_hsa05213 | 0.50677171 |
| 86 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.49919184 |
| 87 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.46241012 |
| 88 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.44952484 |
| 89 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.44506424 |
| 90 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.41611005 |
| 91 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.40113706 |
| 92 | Glioma_Homo sapiens_hsa05214 | 0.39276368 |
| 93 | Salivary secretion_Homo sapiens_hsa04970 | 0.38828229 |
| 94 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.37744211 |
| 95 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.35899111 |
| 96 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.35691273 |
| 97 | Bile secretion_Homo sapiens_hsa04976 | 0.35448259 |
| 98 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.34941243 |
| 99 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.33349602 |
| 100 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.33099788 |

