KIF9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1plasma membrane fusion (GO:0045026)9.97348565
2acrosome reaction (GO:0007340)9.77736677
3piRNA metabolic process (GO:0034587)9.59143771
4epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)9.40609321
5binding of sperm to zona pellucida (GO:0007339)9.31213008
6cell-cell recognition (GO:0009988)9.30657337
7regulation of cilium movement (GO:0003352)9.07860488
8reproduction (GO:0000003)8.71640465
9spermatid development (GO:0007286)8.57928277
10male meiosis (GO:0007140)8.09861475
11synaptonemal complex organization (GO:0070193)7.48553395
12single fertilization (GO:0007338)7.30700856
13synaptonemal complex assembly (GO:0007130)7.02111525
14mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.29919755
15ventricular system development (GO:0021591)6.24787076
16fertilization (GO:0009566)6.18872929
17DNA methylation involved in gamete generation (GO:0043046)6.11866829
18sperm capacitation (GO:0048240)6.08379404
19negative regulation of inclusion body assembly (GO:0090084)5.86415197
20male meiosis I (GO:0007141)5.80218342
21spermatogenesis (GO:0007283)5.72745295
22ATP synthesis coupled proton transport (GO:0015986)5.72392766
23energy coupled proton transport, down electrochemical gradient (GO:0015985)5.72392766
24male gamete generation (GO:0048232)5.70494767
25protein localization to cilium (GO:0061512)5.63149722
26axoneme assembly (GO:0035082)5.61370448
27regulation of microtubule-based movement (GO:0060632)5.40596855
28gamete generation (GO:0007276)5.27600042
29mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.23293929
30intraciliary transport (GO:0042073)5.15096960
31chromosome organization involved in meiosis (GO:0070192)4.99368681
32microtubule depolymerization (GO:0007019)4.97688846
33organic cation transport (GO:0015695)4.97537123
34establishment of protein localization to mitochondrial membrane (GO:0090151)4.95328456
35cellular process involved in reproduction in multicellular organism (GO:0022412)4.93437625
36germ cell development (GO:0007281)4.91800724
37microtubule severing (GO:0051013)4.89382444
38calcium ion-dependent exocytosis (GO:0017156)4.71444675
39regulation of inclusion body assembly (GO:0090083)4.70407117
40meiosis I (GO:0007127)4.66988588
41meiotic nuclear division (GO:0007126)4.65577326
42protein complex biogenesis (GO:0070271)4.62161439
43electron transport chain (GO:0022900)4.61856454
44cell recognition (GO:0008037)4.61714588
45respiratory electron transport chain (GO:0022904)4.59518473
46ribosomal small subunit assembly (GO:0000028)4.57455340
47mitochondrial respiratory chain complex I assembly (GO:0032981)4.42168278
48NADH dehydrogenase complex assembly (GO:0010257)4.42168278
49mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.42168278
50meiotic cell cycle (GO:0051321)4.35948454
51viral transcription (GO:0019083)4.35321665
52translational termination (GO:0006415)4.29678789
53protein polyglutamylation (GO:0018095)4.28838059
54mitochondrial respiratory chain complex assembly (GO:0033108)4.28155132
55seminiferous tubule development (GO:0072520)4.22541504
56cilium organization (GO:0044782)4.17270476
57multicellular organismal reproductive process (GO:0048609)4.16426084
58left/right pattern formation (GO:0060972)4.14649820
59nucleoside diphosphate phosphorylation (GO:0006165)4.11646731
60cilium morphogenesis (GO:0060271)4.04505995
61GTP biosynthetic process (GO:0006183)4.01961572
62cilium assembly (GO:0042384)4.01440393
63SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.00188633
64cotranslational protein targeting to membrane (GO:0006613)3.99721537
65protein targeting to ER (GO:0045047)3.93267657
66nonmotile primary cilium assembly (GO:0035058)3.80908219
67maturation of SSU-rRNA (GO:0030490)3.78712386
68establishment of protein localization to endoplasmic reticulum (GO:0072599)3.78360848
69chaperone-mediated protein transport (GO:0072321)3.76226610
70protein localization to endoplasmic reticulum (GO:0070972)3.70870602
71base-excision repair, AP site formation (GO:0006285)3.70176132
72protein neddylation (GO:0045116)3.68088333
73centriole assembly (GO:0098534)3.66361333
74ribosomal small subunit biogenesis (GO:0042274)3.64843646
75* microtubule-based movement (GO:0007018)3.63574976
76translational elongation (GO:0006414)3.63234157
77cellular component assembly involved in morphogenesis (GO:0010927)3.62853932
78genitalia morphogenesis (GO:0035112)3.61807657
79gene silencing by RNA (GO:0031047)3.61010952
80pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.59378009
81monoubiquitinated protein deubiquitination (GO:0035520)3.53668284
82spermatid nucleus differentiation (GO:0007289)3.53128012
83UTP biosynthetic process (GO:0006228)3.52520278
84purine nucleoside triphosphate biosynthetic process (GO:0009145)3.49030772
85respiratory chain complex IV assembly (GO:0008535)3.48471155
86purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.45593796
87ATP biosynthetic process (GO:0006754)3.38809187
88centriole replication (GO:0007099)3.37881428
89cellular protein complex disassembly (GO:0043624)3.35037186
90left/right axis specification (GO:0070986)3.33293494
91glycerol ether metabolic process (GO:0006662)3.28119246
92multicellular organismal development (GO:0007275)3.27738920
93viral life cycle (GO:0019058)3.22708015
94cytochrome complex assembly (GO:0017004)3.21956785
95transcription elongation from RNA polymerase III promoter (GO:0006385)3.20949071
96termination of RNA polymerase III transcription (GO:0006386)3.20949071
97hydrogen ion transmembrane transport (GO:1902600)3.20002345
98lactate metabolic process (GO:0006089)3.19453919
99synapsis (GO:0007129)3.19325100
100UTP metabolic process (GO:0046051)3.15868812
101neuron fate determination (GO:0048664)3.11532941
102regulation of meiosis I (GO:0060631)3.09829767
103chaperone-mediated protein complex assembly (GO:0051131)3.07376790
104alditol metabolic process (GO:0019400)3.05792005
105nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.04022326
106polyol catabolic process (GO:0046174)3.03672980
107ether metabolic process (GO:0018904)3.03398668
108water-soluble vitamin biosynthetic process (GO:0042364)3.02925849
109nucleoside triphosphate biosynthetic process (GO:0009142)3.02815091
110rRNA modification (GO:0000154)3.01331464
111translational initiation (GO:0006413)3.00373678
112guanosine-containing compound biosynthetic process (GO:1901070)2.99239891
113meiotic cell cycle process (GO:1903046)2.98453236
114ribonucleoside triphosphate biosynthetic process (GO:0009201)2.97251851
115smoothened signaling pathway (GO:0007224)2.95395897
116proton transport (GO:0015992)2.94349517
117ribosomal large subunit biogenesis (GO:0042273)2.94097077
118microtubule bundle formation (GO:0001578)2.92065491
119nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.90874404
120protein K11-linked deubiquitination (GO:0035871)2.89430776
121mannosylation (GO:0097502)2.88660535
122hydrogen transport (GO:0006818)2.87350144
123regulation of mitochondrial translation (GO:0070129)2.86648871
124translation (GO:0006412)2.86265349
125proteasome assembly (GO:0043248)2.85549281
126intracellular protein transmembrane import (GO:0044743)2.84880608
127behavioral response to nicotine (GO:0035095)2.82804026
128aldehyde catabolic process (GO:0046185)2.82248815
129protein complex disassembly (GO:0043241)2.81473142
130glycerol metabolic process (GO:0006071)2.79664950
131determination of left/right symmetry (GO:0007368)2.77575058
132regulation of chromatin binding (GO:0035561)2.77221002
133sequestering of actin monomers (GO:0042989)2.76510327
134inner mitochondrial membrane organization (GO:0007007)2.75777387
135exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.74647106
136pyrimidine nucleotide catabolic process (GO:0006244)2.74629618
137response to pheromone (GO:0019236)2.74352745
138peptidyl-glutamic acid modification (GO:0018200)2.74227311
139negative regulation of organelle assembly (GO:1902116)2.71564733
140pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.71118131
141macromolecular complex disassembly (GO:0032984)2.70902245
142carnitine transport (GO:0015879)2.69771500
143amino-acid betaine transport (GO:0015838)2.69771500
144regulation of protein polyubiquitination (GO:1902914)2.68908928
145protein refolding (GO:0042026)2.68382667
146carnitine transmembrane transport (GO:1902603)2.66159441
147cellular component biogenesis (GO:0044085)2.62817153
148CTP metabolic process (GO:0046036)2.62532707
149CTP biosynthetic process (GO:0006241)2.62532707
150regulation of centriole replication (GO:0046599)2.61720866
151rRNA methylation (GO:0031167)2.61332650
152chromosome condensation (GO:0030261)2.60889292
153platelet dense granule organization (GO:0060155)2.60598269
154determination of bilateral symmetry (GO:0009855)2.59590269
155preassembly of GPI anchor in ER membrane (GO:0016254)2.58838095
156microtubule polymerization or depolymerization (GO:0031109)2.58102107
157cell projection assembly (GO:0030031)2.56573159
158specification of symmetry (GO:0009799)2.55622911
159interferon-gamma secretion (GO:0072643)2.55303383
160regulation of spindle checkpoint (GO:0090231)2.54527462
161cilium or flagellum-dependent cell motility (GO:0001539)15.3990332
162fusion of sperm to egg plasma membrane (GO:0007342)13.0932912
163axonemal dynein complex assembly (GO:0070286)12.1379947
164sperm motility (GO:0030317)11.1257163
165multicellular organism reproduction (GO:0032504)10.8204346
166acrosome assembly (GO:0001675)10.6463496
167epithelial cilium movement (GO:0003351)10.6020524
168cell wall macromolecule catabolic process (GO:0016998)10.4627190
169cell wall macromolecule metabolic process (GO:0044036)10.4627190
170sperm-egg recognition (GO:0035036)10.3720461
171cilium movement (GO:0003341)10.2007730
172motile cilium assembly (GO:0044458)10.0741727

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.28506639
2EZH2_22144423_ChIP-Seq_EOC_Human5.31127144
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.91029817
4* GABP_17652178_ChIP-ChIP_JURKAT_Human4.09588684
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.93115249
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.86708774
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.75136080
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.48683429
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.29689206
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.02091705
11HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.54773951
12* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.49690927
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.42261309
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.41800962
15FLI1_27457419_Chip-Seq_LIVER_Mouse2.40590170
16PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.27738963
17ELK1_19687146_ChIP-ChIP_HELA_Human2.27337530
18ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.22910582
19FUS_26573619_Chip-Seq_HEK293_Human2.22190511
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.18506256
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.16080536
22PCGF2_27294783_Chip-Seq_ESCs_Mouse2.11416607
23VDR_23849224_ChIP-Seq_CD4+_Human2.07938612
24SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.07450456
25EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.01904189
26EWS_26573619_Chip-Seq_HEK293_Human2.00149080
27GATA1_26923725_Chip-Seq_HPCs_Mouse1.91315109
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.87784089
29IGF1R_20145208_ChIP-Seq_DFB_Human1.87686617
30GBX2_23144817_ChIP-Seq_PC3_Human1.86007715
31SRF_21415370_ChIP-Seq_HL-1_Mouse1.85904926
32ELK4_26923725_Chip-Seq_MESODERM_Mouse1.82286995
33ZNF274_21170338_ChIP-Seq_K562_Hela1.81801711
34* MYC_18940864_ChIP-ChIP_HL60_Human1.80757823
35VDR_22108803_ChIP-Seq_LS180_Human1.72506900
36CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.68385841
37STAT1_17558387_ChIP-Seq_HELA_Human1.65941561
38KAP1_22055183_ChIP-Seq_ESCs_Mouse1.65832467
39PCGF2_27294783_Chip-Seq_NPCs_Mouse1.65503787
40KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.62383557
41TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.61928874
42NFE2_27457419_Chip-Seq_LIVER_Mouse1.61241949
43TAL1_26923725_Chip-Seq_HPCs_Mouse1.61013314
44POU3F2_20337985_ChIP-ChIP_501MEL_Human1.59319674
45* FOXP3_21729870_ChIP-Seq_TREG_Human1.59160566
46STAT6_21828071_ChIP-Seq_BEAS2B_Human1.59051280
47CBX2_27304074_Chip-Seq_ESCs_Mouse1.58755630
48P300_19829295_ChIP-Seq_ESCs_Human1.58378340
49SUZ12_27294783_Chip-Seq_NPCs_Mouse1.56144638
50WDR5_24793694_ChIP-Seq_LNCAP_Human1.55532745
51MYC_18555785_ChIP-Seq_MESCs_Mouse1.53547364
52NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.51542318
53ZFP57_27257070_Chip-Seq_ESCs_Mouse1.50949954
54GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.50926765
55MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.50770362
56PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.49311078
57PADI4_21655091_ChIP-ChIP_MCF-7_Human1.48486743
58* TTF2_22483619_ChIP-Seq_HELA_Human1.48263544
59TP53_22573176_ChIP-Seq_HFKS_Human1.47736141
60RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.47279559
61TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.46867044
62ELF1_17652178_ChIP-ChIP_JURKAT_Human1.46181359
63KDM2B_26808549_Chip-Seq_REH_Human1.45669236
64TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.44987678
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.44980207
66CBP_20019798_ChIP-Seq_JUKART_Human1.44206545
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.44206545
68BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39614611
69RNF2_27304074_Chip-Seq_NSC_Mouse1.39377869
70DCP1A_22483619_ChIP-Seq_HELA_Human1.33376962
71REST_21632747_ChIP-Seq_MESCs_Mouse1.32916583
72GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.32356382
73* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.32284450
74POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29046755
75TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29046755
76* GABP_19822575_ChIP-Seq_HepG2_Human1.28402018
77NANOG_18555785_Chip-Seq_ESCs_Mouse1.28138425
78GATA3_21867929_ChIP-Seq_CD8_Mouse1.28109406
79GF1_26923725_Chip-Seq_HPCs_Mouse1.26718670
80EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.25784459
81FLI1_21867929_ChIP-Seq_TH2_Mouse1.25469915
82CTBP2_25329375_ChIP-Seq_LNCAP_Human1.25394762
83GATA3_21867929_ChIP-Seq_TH1_Mouse1.23915939
84SOX2_22085726_ChIP-Seq_NPCs_Mouse1.22642983
85TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21239949
86* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.20635653
87MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.20394714
88AR_20517297_ChIP-Seq_VCAP_Human1.20078456
89CRX_20693478_ChIP-Seq_RETINA_Mouse1.20065896
90FOXA1_25329375_ChIP-Seq_VCAP_Human1.19916020
91FOXA1_27270436_Chip-Seq_PROSTATE_Human1.19916020
92NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.19776875
93P53_22387025_ChIP-Seq_ESCs_Mouse1.19699205
94TAF15_26573619_Chip-Seq_HEK293_Human1.19266513
95IRF1_19129219_ChIP-ChIP_H3396_Human1.19199157
96OCT4_18555785_Chip-Seq_ESCs_Mouse1.19190736
97FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18751362
98XRN2_22483619_ChIP-Seq_HELA_Human1.18345001
99ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.17731509
100EZH2_27294783_Chip-Seq_NPCs_Mouse1.16528077
101* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.16465721
102ELK1_22589737_ChIP-Seq_MCF10A_Human1.16447360
103EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.14982375
104NANOG_19829295_ChIP-Seq_ESCs_Human1.14579658
105SOX2_19829295_ChIP-Seq_ESCs_Human1.14579658
106CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.14116343
107* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.13885832
108MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.12127134
109CMYC_18555785_Chip-Seq_ESCs_Mouse1.11594876
110PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.10897142
111SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.09728059
112RUNX1_26923725_Chip-Seq_HPCs_Mouse1.09657162
113P300_18555785_Chip-Seq_ESCs_Mouse1.08374090
114KLF4_18555785_Chip-Seq_ESCs_Mouse1.07623689
115GF1B_26923725_Chip-Seq_HPCs_Mouse1.07620754
116YY1_21170310_ChIP-Seq_MESCs_Mouse1.06953783
117OCT4_21477851_ChIP-Seq_ESCs_Mouse1.06823239
118PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06218894
119POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.06032448
120CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.05982803
121SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05956094
122CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05800490
123LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.05762242
124ESRRB_18555785_Chip-Seq_ESCs_Mouse1.05494306
125GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.04831221
126STAT3_18555785_Chip-Seq_ESCs_Mouse1.03941014
127BCAT_22108803_ChIP-Seq_LS180_Human1.03280023
128HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.02809059
129PU1_27457419_Chip-Seq_LIVER_Mouse1.02202249
130PHF8_20622853_ChIP-Seq_HELA_Human1.01829432
131P53_21459846_ChIP-Seq_SAOS-2_Human1.01767633
132ERG_20517297_ChIP-Seq_VCAP_Human1.01327239
133SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.01020145
134UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00619797
135FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.00383041
136TCF4_22108803_ChIP-Seq_LS180_Human0.99751584
137POU5F1_16153702_ChIP-ChIP_HESCs_Human0.99630231
138EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99122988
139THAP11_20581084_ChIP-Seq_MESCs_Mouse0.98693985
140NCOR_22424771_ChIP-Seq_293T_Human0.98659123
141RUNX1_27457419_Chip-Seq_LIVER_Mouse0.97776261
142E2F4_17652178_ChIP-ChIP_JURKAT_Human0.97165180
143SOX2_18555785_Chip-Seq_ESCs_Mouse0.96992183
144PIAS1_25552417_ChIP-Seq_VCAP_Human0.96492430
145TCF4_23295773_ChIP-Seq_U87_Human0.96470871
146* SMAD4_21799915_ChIP-Seq_A2780_Human0.95936650
147ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.95612690
148ZFX_18555785_Chip-Seq_ESCs_Mouse0.95446749
149SOX2_16153702_ChIP-ChIP_HESCs_Human0.95288431
150ER_23166858_ChIP-Seq_MCF-7_Human0.94997100
151SMAD4_21741376_ChIP-Seq_EPCs_Human0.94950170
152FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.94940386
153AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94374368
154E2F1_18555785_Chip-Seq_ESCs_Mouse0.94045886
155AR_25329375_ChIP-Seq_VCAP_Human0.93977654
156E2F1_18555785_ChIP-Seq_MESCs_Mouse0.93958361
157RAD21_21589869_ChIP-Seq_MESCs_Mouse0.93637880
158* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.92820802
159GATA3_21878914_ChIP-Seq_MCF-7_Human0.92087327
160CTCF_18555785_Chip-Seq_ESCs_Mouse0.92080573
161NR3C1_21868756_ChIP-Seq_MCF10A_Human0.90884042
162CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90772491
163CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.89220749
164PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.88780640
165MYC_19030024_ChIP-ChIP_MESCs_Mouse0.88749106
166KLF5_20875108_ChIP-Seq_MESCs_Mouse0.88489424
167NFYB_21822215_ChIP-Seq_K562_Human0.88210199
168PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.88137718
169HTT_18923047_ChIP-ChIP_STHdh_Human0.87836358
170TBL1_22424771_ChIP-Seq_293T_Human0.87782235
171CTBP1_25329375_ChIP-Seq_LNCAP_Human0.87534047
172RBPJ_21746931_ChIP-Seq_IB4_Human0.85651342
173ETV1_20927104_ChIP-Seq_GIST48_Human0.85160469

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.78912680
2MP0001929_abnormal_gametogenesis5.31652815
3MP0008877_abnormal_DNA_methylation4.98097002
4MP0002653_abnormal_ependyma_morphology4.06229766
5MP0002210_abnormal_sex_determination3.70059900
6MP0009379_abnormal_foot_pigmentation3.64580245
7MP0001984_abnormal_olfaction3.32334561
8MP0002161_abnormal_fertility/fecundity3.08617101
9MP0001145_abnormal_male_reproductive3.07450144
10MP0000653_abnormal_sex_gland2.70663510
11MP0003136_yellow_coat_color2.70309180
12MP0006292_abnormal_olfactory_placode2.68375549
13MP0005084_abnormal_gallbladder_morpholo2.41930695
14MP0005623_abnormal_meninges_morphology2.29487981
15MP0002160_abnormal_reproductive_system2.26434812
16MP0001529_abnormal_vocalization2.25076872
17MP0010030_abnormal_orbit_morphology2.21845196
18MP0002938_white_spotting2.07108675
19MP0005410_abnormal_fertilization14.5545414
20MP0008875_abnormal_xenobiotic_pharmacok1.95338446
21MP0005670_abnormal_white_adipose1.93542434
22MP0002638_abnormal_pupillary_reflex1.86921672
23MP0004142_abnormal_muscle_tone1.77867077
24MP0003806_abnormal_nucleotide_metabolis1.73706466
25MP0003880_abnormal_central_pattern1.70079305
26MP0000372_irregular_coat_pigmentation1.62070901
27MP0003122_maternal_imprinting1.57048887
28MP0003718_maternal_effect1.53959860
29MP0006276_abnormal_autonomic_nervous1.51783976
30MP0001905_abnormal_dopamine_level1.48433333
31MP0009046_muscle_twitch1.44844025
32MP0002277_abnormal_respiratory_mucosa1.41704470
33MP0008058_abnormal_DNA_repair1.37744615
34MP0003186_abnormal_redox_activity1.37605177
35MP0002282_abnormal_trachea_morphology1.34812866
36MP0006036_abnormal_mitochondrial_physio1.32888888
37MP0003121_genomic_imprinting1.25552527
38MP0004043_abnormal_pH_regulation1.24791641
39MP0002233_abnormal_nose_morphology1.24558823
40MP0004885_abnormal_endolymph1.23221803
41MP0008057_abnormal_DNA_replication1.22880878
42MP0005389_reproductive_system_phenotype1.21966447
43MP0005647_abnormal_sex_gland1.21953130
44MP0000049_abnormal_middle_ear1.15627936
45MP0009745_abnormal_behavioral_response1.11981046
46MP0002272_abnormal_nervous_system1.11094964
47MP0002734_abnormal_mechanical_nocicepti1.10256005
48MP0002928_abnormal_bile_duct1.10084230
49MP0003937_abnormal_limbs/digits/tail_de1.09955782
50MP0008872_abnormal_physiological_respon1.06746153
51MP0003938_abnormal_ear_development1.06357178
52MP0002837_dystrophic_cardiac_calcinosis1.04577897
53MP0008995_early_reproductive_senescence1.03661929
54MP0005377_hearing/vestibular/ear_phenot1.02416825
55MP0003878_abnormal_ear_physiology1.02416825
56MP0001286_abnormal_eye_development0.95116806
57MP0003787_abnormal_imprinting0.94461297
58MP0005645_abnormal_hypothalamus_physiol0.94055152
59MP0002102_abnormal_ear_morphology0.90296252
60MP0002095_abnormal_skin_pigmentation0.89487522
61MP0005551_abnormal_eye_electrophysiolog0.88698334
62MP0001765_abnormal_ion_homeostasis0.87702692
63MP0003646_muscle_fatigue0.86552689
64MP0002163_abnormal_gland_morphology0.85772560
65MP0004742_abnormal_vestibular_system0.84784744
66MP0002067_abnormal_sensory_capabilities0.84775197
67MP0004233_abnormal_muscle_weight0.80766431
68MP0005174_abnormal_tail_pigmentation0.79899785
69MP0003283_abnormal_digestive_organ0.78500263
70MP0003011_delayed_dark_adaptation0.78350342
71MP0002132_abnormal_respiratory_system0.77356832
72MP0005253_abnormal_eye_physiology0.74886424
73MP0001970_abnormal_pain_threshold0.73883900
74MP0002822_catalepsy0.72754916
75MP0003252_abnormal_bile_duct0.72549841
76MP0005646_abnormal_pituitary_gland0.71035604
77MP0000383_abnormal_hair_follicle0.69951292
78MP0002184_abnormal_innervation0.69448689
79MP0000955_abnormal_spinal_cord0.67499486
80MP0005423_abnormal_somatic_nervous0.66051950
81MP0003183_abnormal_peptide_metabolism0.65454309
82MP0010094_abnormal_chromosome_stability0.63993716
83MP0001986_abnormal_taste_sensitivity0.62783522
84MP0001346_abnormal_lacrimal_gland0.61450862
85MP0003786_premature_aging0.60151769
86MP0008789_abnormal_olfactory_epithelium0.57284536
87MP0002736_abnormal_nociception_after0.54514930
88MP0001119_abnormal_female_reproductive0.53566521
89MP0003879_abnormal_hair_cell0.51882726
90MP0003115_abnormal_respiratory_system0.51863643
91MP0005499_abnormal_olfactory_system0.51050979
92MP0005394_taste/olfaction_phenotype0.51050979
93MP0002254_reproductive_system_inflammat0.50618277
94MP0005391_vision/eye_phenotype0.49119456
95MP0001963_abnormal_hearing_physiology0.45991717
96MP0002557_abnormal_social/conspecific_i0.45506901
97MP0002234_abnormal_pharynx_morphology0.45283481
98MP0001764_abnormal_homeostasis0.44922298
99MP0002876_abnormal_thyroid_physiology0.44379417
100MP0001324_abnormal_eye_pigmentation0.42972316
101MP0000427_abnormal_hair_cycle0.42898925
102MP0000026_abnormal_inner_ear0.42882864
103MP0003699_abnormal_female_reproductive0.42763155
104MP0009115_abnormal_fat_cell0.42596112
105MP0005397_hematopoietic_system_phenotyp0.41951142
106MP0001545_abnormal_hematopoietic_system0.41951142
107MP0002152_abnormal_brain_morphology0.41253305
108MP0006082_CNS_inflammation0.40536998
109MP0001968_abnormal_touch/_nociception0.40179506
110MP0008007_abnormal_cellular_replicative0.40004757
111MP0004134_abnormal_chest_morphology0.39989516
112MP0002405_respiratory_system_inflammati0.39675697
113MP0001849_ear_inflammation0.38806927
114MP0002971_abnormal_brown_adipose0.38578428
115MP0004133_heterotaxia0.38410487
116MP0002909_abnormal_adrenal_gland0.37365885
117MP0001502_abnormal_circadian_rhythm0.37068338
118MP0002572_abnormal_emotion/affect_behav0.35638063
119MP0008961_abnormal_basal_metabolism0.34943270
120MP0005666_abnormal_adipose_tissue0.34776844
121MP0002752_abnormal_somatic_nervous0.33737048
122MP0010386_abnormal_urinary_bladder0.33643913
123MP0003861_abnormal_nervous_system0.33510214
124MP0006072_abnormal_retinal_apoptosis0.32392542
125MP0000566_synostosis0.32188661
126MP0005636_abnormal_mineral_homeostasis0.32003106
127MP0002229_neurodegeneration0.31057281
128MP0005195_abnormal_posterior_eye0.30991320
129MP0001270_distended_abdomen0.30759743
130MP0004811_abnormal_neuron_physiology0.30757358
131MP0000015_abnormal_ear_pigmentation0.30305028
132MP0003942_abnormal_urinary_system0.30232607
133MP0001485_abnormal_pinna_reflex0.30198644
134MP0003634_abnormal_glial_cell0.30184432
135MP0003890_abnormal_embryonic-extraembry0.29739882
136MP0009278_abnormal_bone_marrow0.29135100
137MP0000569_abnormal_digit_pigmentation0.28866633
138MP0000631_abnormal_neuroendocrine_gland0.28594332
139MP0004019_abnormal_vitamin_homeostasis0.26930215
140MP0000778_abnormal_nervous_system0.26469231
141MP0004808_abnormal_hematopoietic_stem0.26265009
142MP0001486_abnormal_startle_reflex0.25371631
143MP0003633_abnormal_nervous_system0.25168901
144MP0000358_abnormal_cell_content/0.24898066
145MP0001293_anophthalmia0.24795845

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory epithelium morphology (HP:0012253)9.34673372
2Abnormal respiratory motile cilium morphology (HP:0005938)9.34673372
3Abnormal ciliary motility (HP:0012262)8.91214788
4Rhinitis (HP:0012384)8.58340385
5Chronic bronchitis (HP:0004469)7.46581012
6Nasal polyposis (HP:0100582)6.09115048
7Infertility (HP:0000789)5.83564770
8Bronchiectasis (HP:0002110)5.13551899
9Abnormality of the nasal mucosa (HP:0000433)4.93839997
10Bronchitis (HP:0012387)4.45019715
11Acute necrotizing encephalopathy (HP:0006965)4.30702869
12Nephronophthisis (HP:0000090)4.26757580
13Acute encephalopathy (HP:0006846)3.80747202
14Abnormal mitochondria in muscle tissue (HP:0008316)3.77446416
15Mitochondrial inheritance (HP:0001427)3.60576486
16Progressive macrocephaly (HP:0004481)3.60197605
17Recurrent sinusitis (HP:0011108)3.53100397
18Medial flaring of the eyebrow (HP:0010747)3.44307140
19Male infertility (HP:0003251)3.38438463
20Abnormality of the renal medulla (HP:0100957)3.29140174
21Recurrent otitis media (HP:0000403)3.16447085
22Increased CSF lactate (HP:0002490)3.12022299
23Molar tooth sign on MRI (HP:0002419)3.04193195
24Abnormality of midbrain morphology (HP:0002418)3.04193195
25Increased hepatocellular lipid droplets (HP:0006565)2.77307610
26Hepatocellular necrosis (HP:0001404)2.76449156
27Tubulointerstitial nephritis (HP:0001970)2.69544512
28Sclerocornea (HP:0000647)2.66713063
29Type II lissencephaly (HP:0007260)2.65327362
303-Methylglutaconic aciduria (HP:0003535)2.64528005
31Cerebral edema (HP:0002181)2.64403532
32Abnormality of cells of the erythroid lineage (HP:0012130)2.63160897
33Lipid accumulation in hepatocytes (HP:0006561)2.62896447
34Abnormal number of erythroid precursors (HP:0012131)2.62182257
35Gait imbalance (HP:0002141)2.62108269
36Congenital primary aphakia (HP:0007707)2.60362486
37Chronic sinusitis (HP:0011109)2.51821238
38Hepatic necrosis (HP:0002605)2.49675585
39Recurrent bronchitis (HP:0002837)2.43978851
40Male pseudohermaphroditism (HP:0000037)2.42437255
41Abnormal spermatogenesis (HP:0008669)2.40939857
42Median cleft lip (HP:0000161)2.40455630
43Tubular atrophy (HP:0000092)2.38113410
44Anencephaly (HP:0002323)2.34710136
45Renal Fanconi syndrome (HP:0001994)2.34253417
46Pancreatic fibrosis (HP:0100732)2.32927950
47Nephrogenic diabetes insipidus (HP:0009806)2.31621288
48Postaxial foot polydactyly (HP:0001830)2.29184244
49Tubulointerstitial abnormality (HP:0001969)2.27537960
50Reticulocytopenia (HP:0001896)2.25794625
51Cerebellar dysplasia (HP:0007033)2.22332720
52Optic disc pallor (HP:0000543)2.15053310
53Congenital hepatic fibrosis (HP:0002612)2.14307605
54Gonadotropin excess (HP:0000837)2.09647454
55Supernumerary spleens (HP:0009799)2.05704875
56Facial cleft (HP:0002006)2.05529162
57Poor coordination (HP:0002370)2.03750669
58Furrowed tongue (HP:0000221)2.03116899
59Abnormality of the lower motor neuron (HP:0002366)2.02220306
60Impulsivity (HP:0100710)2.01612566
61Fibular hypoplasia (HP:0003038)2.01053460
62Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.3187978
63Dynein arm defect of respiratory motile cilia (HP:0012255)11.8278152
64Absent/shortened dynein arms (HP:0200106)11.8278152
65Abnormal respiratory motile cilium physiology (HP:0012261)10.3017533
66Stage 5 chronic kidney disease (HP:0003774)1.99691057
67Macrocytic anemia (HP:0001972)1.99009013
68Abnormality of permanent molar morphology (HP:0011071)1.98450370
69Abnormality of the dental root (HP:0006486)1.98450370
70Taurodontia (HP:0000679)1.98450370
71Postaxial hand polydactyly (HP:0001162)1.97717586
72Respiratory failure (HP:0002878)1.97570505
73True hermaphroditism (HP:0010459)1.97382817
74Genital tract atresia (HP:0001827)1.95622943
75Congenital, generalized hypertrichosis (HP:0004540)1.94488618
76Exercise intolerance (HP:0003546)1.93645474
77Vaginal atresia (HP:0000148)1.92971584
78Azoospermia (HP:0000027)1.92800273
79Decreased activity of mitochondrial respiratory chain (HP:0008972)1.92653064
80Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.92653064
81Cystic liver disease (HP:0006706)1.91946396
82Type I transferrin isoform profile (HP:0003642)1.91529407
83Tubulointerstitial fibrosis (HP:0005576)1.88876541
84Aplasia/Hypoplasia of the lens (HP:0008063)1.88077683
85Polydipsia (HP:0001959)1.84528946
86Abnormal drinking behavior (HP:0030082)1.84528946
87Leukodystrophy (HP:0002415)1.84473156
88Abnormality of molar morphology (HP:0011070)1.83927311
89Abnormality of molar (HP:0011077)1.83927311
90Oculomotor apraxia (HP:0000657)1.82227303
91Decreased central vision (HP:0007663)1.81158844
92Abnormality of the dental pulp (HP:0006479)1.80884307
93Lactic acidosis (HP:0003128)1.80537637
94Aplasia/Hypoplasia of the tongue (HP:0010295)1.78167908
95Bile duct proliferation (HP:0001408)1.77988368
96Abnormal biliary tract physiology (HP:0012439)1.77988368
97Exertional dyspnea (HP:0002875)1.77920797
98Concave nail (HP:0001598)1.76210561
99Methylmalonic acidemia (HP:0002912)1.74812959
100Congenital stationary night blindness (HP:0007642)1.73182234
101Increased intramyocellular lipid droplets (HP:0012240)1.73042937
102Abnormality of the renal cortex (HP:0011035)1.72550715
103Anophthalmia (HP:0000528)1.72506530
104Abnormal rod and cone electroretinograms (HP:0008323)1.71960539
105Increased serum lactate (HP:0002151)1.71572317
106Abnormality of the pons (HP:0007361)1.71443057
107Renal dysplasia (HP:0000110)1.71047085
108Hypoplasia of the capital femoral epiphysis (HP:0003090)1.69508710
109Abnormality of renal resorption (HP:0011038)1.68913609
110Hypoplasia of the pons (HP:0012110)1.68820117
111Abnormality of dentin (HP:0010299)1.67847839
112Abnormality of the labia minora (HP:0012880)1.65047948
113Aganglionic megacolon (HP:0002251)1.64542200
114Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.64174710
115Impaired proprioception (HP:0010831)1.62924766
116Abnormal glycosylation (HP:0012345)1.62401976
117Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.62401976
118Abnormal protein N-linked glycosylation (HP:0012347)1.62401976
119Abnormal protein glycosylation (HP:0012346)1.62401976
120Hyperglycinemia (HP:0002154)1.62247873
121Occipital encephalocele (HP:0002085)1.61287193
122Pancreatic cysts (HP:0001737)1.59804920
123Amyotrophic lateral sclerosis (HP:0007354)1.57446348
124Abnormality of renal excretion (HP:0011036)1.54349510
125Dyschromatopsia (HP:0007641)1.53153358
126Microglossia (HP:0000171)1.49150359
127Short ribs (HP:0000773)1.48997320
128Nephropathy (HP:0000112)1.47789568
129J-shaped sella turcica (HP:0002680)1.46591470
130Bell-shaped thorax (HP:0001591)1.41551318
131Chronic hepatic failure (HP:0100626)1.40192319
132Short nail (HP:0001799)1.38754484
133Short thorax (HP:0010306)1.32123940
134Breast carcinoma (HP:0003002)1.31381994
135Bony spicule pigmentary retinopathy (HP:0007737)1.29629925
136Absent epiphyses (HP:0010577)1.28040658
137Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.28040658
138Broad distal phalanx of finger (HP:0009836)1.26472182
139Aplasia/Hypoplasia of the fibula (HP:0006492)1.26218439
140Preaxial hand polydactyly (HP:0001177)1.26105681
141Spastic tetraparesis (HP:0001285)1.24734689
142Retinitis pigmentosa (HP:0000510)1.23722484
143Abnormal urine output (HP:0012590)1.22706319
144Absent frontal sinuses (HP:0002688)1.19493602
145Hypoplasia of dental enamel (HP:0006297)1.19117659
146Polyuria (HP:0000103)1.18852065
147Upper motor neuron abnormality (HP:0002127)1.17657119
148Astigmatism (HP:0000483)1.16272878
149Heterotopia (HP:0002282)1.14707947
150Dental crowding (HP:0000678)1.14304778
15111 pairs of ribs (HP:0000878)1.13377364

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK48.42862898
2PDK38.42862898
3PDK25.48220582
4TESK14.53679984
5PRKD33.90445727
6MAPK153.70881785
7ICK3.19410375
8VRK22.98749530
9PNCK2.86911807
10VRK12.76820806
11STK162.75291514
12MST42.58421594
13MAP4K22.48931145
14ZAK2.43052500
15WNK32.42145190
16PTK2B2.26282922
17WNK42.26044711
18STK392.15975498
19FRK2.06877296
20TLK11.97138301
21TSSK61.80416484
22NME11.78645705
23NEK21.77696798
24TNIK1.69741061
25BCKDK1.52730240
26MAP3K121.49572607
27STK381.43788144
28TRIM281.39399399
29ADRBK21.38463072
30DYRK21.37192737
31TAOK31.36725488
32PLK31.36581583
33PASK1.33828859
34IRAK11.28247351
35MKNK21.24929668
36INSRR1.18297997
37NTRK21.16704511
38PBK1.13820569
39CCNB11.13714870
40MAPKAPK31.11471247
41MKNK11.08408184
42EIF2AK11.03397210
43CASK1.01765547
44DYRK1B0.97684353
45LMTK20.96663294
46WNK10.92689056
47TYRO30.91965545
48DYRK30.90887812
49CDK190.90846121
50TAF10.90833812
51BUB10.90234098
52MAPK130.88646609
53STK30.88330720
54PLK20.88024759
55CSNK1G20.85806402
56CDK80.80169438
57PDK10.79155018
58EPHA40.77776310
59TTK0.77442844
60PLK40.74587118
61OXSR10.73661194
62CSNK1G30.73462648
63CSNK1G10.71562498
64CAMK1G0.71473547
65EIF2AK30.71148520
66STK38L0.70746533
67NTRK30.68385134
68BMPR1B0.67069781
69AURKA0.66865759
70MUSK0.66052574
71TIE10.64829524
72RPS6KA50.64575276
73BCR0.61256246
74ABL20.59030902
75PRKCE0.55278463
76PAK30.55165947
77CHEK20.52162735
78CDK120.51811452
79CDK30.49146358
80DYRK1A0.46694550
81WEE10.45928961
82MAP3K20.45194165
83CSNK2A20.44480738
84ADRBK10.42740536
85CSNK1A1L0.41666736
86AURKB0.41515764
87EPHB20.41510138
88NEK60.40106210
89LRRK20.39516213
90TGFBR10.39212270
91PRKACA0.38762442
92PRKCG0.38234104
93PINK10.37218353
94CHEK10.36864973
95CSNK1A10.35388309
96PHKG10.34557714
97PHKG20.34557714
98CSNK1E0.34120769
99PRKCI0.33988236
100ATM0.33802665
101EPHA20.33682567
102ATR0.33565738
103MARK10.33510830
104STK40.32820906
105BRSK10.30893993
106MAP2K70.28973944
107BRAF0.25098882
108ERBB30.24940219
109GRK10.23907100
110PLK10.23499078
111PDPK10.23050091
112RPS6KB10.20176342
113MAP2K60.17875157
114CAMKK10.17473999
115BRSK20.17178036
116PAK10.16946003
117PRKAA10.16574813
118NLK0.15356002
119MARK20.15164164
120MTOR0.14786657
121SRPK10.13079866
122FGFR20.12780090
123CDC70.12227635
124CDK90.11112010
125FER0.10169408
126PRKG10.09820097
127IRAK20.09718515
128PRKCQ0.09641023
129MAPKAPK50.09095497
130TESK20.08762667
131MAP3K40.08661064
132DAPK20.08561500
133PAK40.08071209
134PRKCZ0.06316563
135RIPK40.06034523
136CSK0.05285328
137PKN10.05170208
138STK110.04899267
139BMPR20.04716129
140EPHB10.04441532
141CAMK2A0.04208058
142CDK60.04080790
143GRK50.04068054
144EEF2K0.03253539
145GSK3B0.03027210
146PTK60.02431791
147AKT30.01715655
148PRKDC0.01483864
149CSNK2A10.01402296
150PAK20.01244290
151NUAK10.00830057
152PRKACG0.00745682
153PRKCB-0.0146742
154SGK3-0.0114822
155CSF1R-0.0107701
156SGK2-0.0092007
157EGFR-0.0077338
158CAMK1-0.0058681
159PRKACB-0.0046329
160MAP2K2-0.0039516
161MAPK8-0.0036231
162MAPK10-0.0023908

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.83756898
2Oxidative phosphorylation_Homo sapiens_hsa001904.63905897
3Ribosome_Homo sapiens_hsa030104.31747651
4Parkinsons disease_Homo sapiens_hsa050123.90964059
5Pyruvate metabolism_Homo sapiens_hsa006203.49383963
6Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.35205433
7Basal transcription factors_Homo sapiens_hsa030223.05746875
8Proteasome_Homo sapiens_hsa030502.99916039
9Protein export_Homo sapiens_hsa030602.90428956
10RNA polymerase_Homo sapiens_hsa030202.88456528
11Propanoate metabolism_Homo sapiens_hsa006402.85645558
12Fatty acid biosynthesis_Homo sapiens_hsa000612.85321720
13Glucagon signaling pathway_Homo sapiens_hsa049222.75182507
14Dorso-ventral axis formation_Homo sapiens_hsa043202.66142942
15Alzheimers disease_Homo sapiens_hsa050102.63976611
16Fanconi anemia pathway_Homo sapiens_hsa034602.53278621
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.45234917
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.31318103
19Linoleic acid metabolism_Homo sapiens_hsa005912.29897381
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.29237503
21Olfactory transduction_Homo sapiens_hsa047402.27072594
22Glycosaminoglycan degradation_Homo sapiens_hsa005312.17040572
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.15910566
24Pentose phosphate pathway_Homo sapiens_hsa000302.03279442
25Oocyte meiosis_Homo sapiens_hsa041141.92054866
26Selenocompound metabolism_Homo sapiens_hsa004501.90645143
27Huntingtons disease_Homo sapiens_hsa050161.89308226
28Amphetamine addiction_Homo sapiens_hsa050311.89163657
29Glycerolipid metabolism_Homo sapiens_hsa005611.72388925
30Maturity onset diabetes of the young_Homo sapiens_hsa049501.71954974
31Carbohydrate digestion and absorption_Homo sapiens_hsa049731.68702785
32Nitrogen metabolism_Homo sapiens_hsa009101.66423042
33Glycerophospholipid metabolism_Homo sapiens_hsa005641.66098436
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.64107473
35Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.60333966
36Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.54478887
37Mismatch repair_Homo sapiens_hsa034301.53273706
38Folate biosynthesis_Homo sapiens_hsa007901.51165264
39Renin secretion_Homo sapiens_hsa049241.46911911
40RNA degradation_Homo sapiens_hsa030181.41128946
41Ether lipid metabolism_Homo sapiens_hsa005651.37660256
42Pyrimidine metabolism_Homo sapiens_hsa002401.36326016
43Nucleotide excision repair_Homo sapiens_hsa034201.35711925
44Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.33896943
45Collecting duct acid secretion_Homo sapiens_hsa049661.32400043
46PPAR signaling pathway_Homo sapiens_hsa033201.31414155
47Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.26803197
48Peroxisome_Homo sapiens_hsa041461.26559026
49Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.25631250
50Spliceosome_Homo sapiens_hsa030401.24797798
51Butanoate metabolism_Homo sapiens_hsa006501.23151298
52Taste transduction_Homo sapiens_hsa047421.19925667
53Insulin secretion_Homo sapiens_hsa049111.18190573
54Cysteine and methionine metabolism_Homo sapiens_hsa002701.16661368
55Purine metabolism_Homo sapiens_hsa002301.15525866
56Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15182930
57Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.13162149
58Base excision repair_Homo sapiens_hsa034101.11450472
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.10441369
60DNA replication_Homo sapiens_hsa030301.06251414
61Long-term potentiation_Homo sapiens_hsa047201.05682411
62Fructose and mannose metabolism_Homo sapiens_hsa000511.05517404
63Phototransduction_Homo sapiens_hsa047441.03171020
64One carbon pool by folate_Homo sapiens_hsa006700.98802151
65Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.97294177
66Arachidonic acid metabolism_Homo sapiens_hsa005900.97273732
67Antigen processing and presentation_Homo sapiens_hsa046120.94567802
68mRNA surveillance pathway_Homo sapiens_hsa030150.94189022
69Calcium signaling pathway_Homo sapiens_hsa040200.93770205
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.92327318
71Regulation of autophagy_Homo sapiens_hsa041400.91131646
72Mineral absorption_Homo sapiens_hsa049780.91045044
73Fatty acid elongation_Homo sapiens_hsa000620.88131048
74ABC transporters_Homo sapiens_hsa020100.87671160
75Estrogen signaling pathway_Homo sapiens_hsa049150.87525640
76Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.86311005
77Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.85805400
78Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85337285
79Cardiac muscle contraction_Homo sapiens_hsa042600.85062302
80Tryptophan metabolism_Homo sapiens_hsa003800.84540183
81beta-Alanine metabolism_Homo sapiens_hsa004100.83745771
82Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.83181714
83Circadian entrainment_Homo sapiens_hsa047130.82138040
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.82009886
85Nicotine addiction_Homo sapiens_hsa050330.81695136
86Synaptic vesicle cycle_Homo sapiens_hsa047210.80866636
87Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.80492633
88Phosphatidylinositol signaling system_Homo sapiens_hsa040700.79497143
89cGMP-PKG signaling pathway_Homo sapiens_hsa040220.77126553
90N-Glycan biosynthesis_Homo sapiens_hsa005100.76817482
91Steroid biosynthesis_Homo sapiens_hsa001000.71717522
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.71374635
93Caffeine metabolism_Homo sapiens_hsa002320.70189476
94Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.69903162
95Basal cell carcinoma_Homo sapiens_hsa052170.66796912
96Inositol phosphate metabolism_Homo sapiens_hsa005620.65906863
97RNA transport_Homo sapiens_hsa030130.65859106
98Sphingolipid metabolism_Homo sapiens_hsa006000.65388388
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65107559
100Tyrosine metabolism_Homo sapiens_hsa003500.64996660
101Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63549441
102Primary bile acid biosynthesis_Homo sapiens_hsa001200.63131542
103Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.61722266
104SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61237142
105Other glycan degradation_Homo sapiens_hsa005110.61043979
106Sulfur relay system_Homo sapiens_hsa041220.59792876
107Sulfur metabolism_Homo sapiens_hsa009200.59191214
108Thyroid hormone synthesis_Homo sapiens_hsa049180.57937145
109Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.55379296
110Hedgehog signaling pathway_Homo sapiens_hsa043400.55376790
111Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.54649351
112Chemical carcinogenesis_Homo sapiens_hsa052040.54183800
113cAMP signaling pathway_Homo sapiens_hsa040240.52879111
114Glutathione metabolism_Homo sapiens_hsa004800.52352867
115Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51163164
116Carbon metabolism_Homo sapiens_hsa012000.49698865
117Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.48842633
118Salivary secretion_Homo sapiens_hsa049700.48764359
119Gastric acid secretion_Homo sapiens_hsa049710.48403276
120Histidine metabolism_Homo sapiens_hsa003400.47396134
121Glutamatergic synapse_Homo sapiens_hsa047240.46500968
122Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44978825
123Fatty acid degradation_Homo sapiens_hsa000710.44811739
124Adipocytokine signaling pathway_Homo sapiens_hsa049200.42843458
125Non-homologous end-joining_Homo sapiens_hsa034500.42748292
126B cell receptor signaling pathway_Homo sapiens_hsa046620.42303145
127Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40082448
128GABAergic synapse_Homo sapiens_hsa047270.36734365
129Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.36731905
130Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.36232656
131Arginine and proline metabolism_Homo sapiens_hsa003300.35244132
132Phenylalanine metabolism_Homo sapiens_hsa003600.35054375
133Dopaminergic synapse_Homo sapiens_hsa047280.34164153
134Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33898332
135Vascular smooth muscle contraction_Homo sapiens_hsa042700.33284715
136Aldosterone synthesis and secretion_Homo sapiens_hsa049250.31716309
137Metabolic pathways_Homo sapiens_hsa011000.31278561
138Pancreatic secretion_Homo sapiens_hsa049720.30919094
139Morphine addiction_Homo sapiens_hsa050320.30540119
140Alcoholism_Homo sapiens_hsa050340.30391353
141Fatty acid metabolism_Homo sapiens_hsa012120.30363629
142Homologous recombination_Homo sapiens_hsa034400.29978752
143Legionellosis_Homo sapiens_hsa051340.29636830
144Serotonergic synapse_Homo sapiens_hsa047260.29570137
145Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.29087432
146Drug metabolism - other enzymes_Homo sapiens_hsa009830.28743047
147Fat digestion and absorption_Homo sapiens_hsa049750.27924607
148Cocaine addiction_Homo sapiens_hsa050300.27893292
149Wnt signaling pathway_Homo sapiens_hsa043100.27844551
150Retinol metabolism_Homo sapiens_hsa008300.26375760
151Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.25985319
152Renin-angiotensin system_Homo sapiens_hsa046140.25226755
153Ovarian steroidogenesis_Homo sapiens_hsa049130.25135937
154VEGF signaling pathway_Homo sapiens_hsa043700.23745370
155Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.23016641
156Endocytosis_Homo sapiens_hsa041440.21074745
157AMPK signaling pathway_Homo sapiens_hsa041520.20837268
158Vibrio cholerae infection_Homo sapiens_hsa051100.17563843
159Rheumatoid arthritis_Homo sapiens_hsa053230.17036958
160Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.16925878
161Biosynthesis of amino acids_Homo sapiens_hsa012300.16740456
162Bile secretion_Homo sapiens_hsa049760.16694979

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