KIFAP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.67353767
2vocalization behavior (GO:0071625)5.36094809
3synaptic vesicle exocytosis (GO:0016079)5.24767830
4synaptic vesicle maturation (GO:0016188)5.23744544
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.14498472
6neuron cell-cell adhesion (GO:0007158)5.06442497
7locomotory exploration behavior (GO:0035641)5.05353469
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.02673187
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.00981919
10protein localization to synapse (GO:0035418)4.91076694
11glutamate secretion (GO:0014047)4.90171546
12nucleobase catabolic process (GO:0046113)4.89745548
13regulation of synaptic vesicle exocytosis (GO:2000300)4.72735709
14regulation of glutamate receptor signaling pathway (GO:1900449)4.59683215
15exploration behavior (GO:0035640)4.44139293
16layer formation in cerebral cortex (GO:0021819)4.43734707
17ionotropic glutamate receptor signaling pathway (GO:0035235)4.40353054
18synaptic vesicle docking involved in exocytosis (GO:0016081)4.24331819
19neuron recognition (GO:0008038)4.21881484
20neuronal action potential propagation (GO:0019227)4.18005466
21regulation of synaptic vesicle transport (GO:1902803)4.17633474
22neurotransmitter secretion (GO:0007269)4.08999982
23regulation of long-term neuronal synaptic plasticity (GO:0048169)4.08482869
24glutamate receptor signaling pathway (GO:0007215)4.08239694
25establishment of mitochondrion localization (GO:0051654)3.97179921
26regulation of neuronal synaptic plasticity (GO:0048168)3.96181194
27dendritic spine morphogenesis (GO:0060997)3.95928380
28regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.94473583
29regulation of synapse structural plasticity (GO:0051823)3.93571040
30synaptic transmission, glutamatergic (GO:0035249)3.91611051
31neuron-neuron synaptic transmission (GO:0007270)3.85282215
32axonal fasciculation (GO:0007413)3.78071339
33proline transport (GO:0015824)3.71169516
34positive regulation of synapse maturation (GO:0090129)3.68644962
35neurotransmitter-gated ion channel clustering (GO:0072578)3.67116136
36protein localization to cilium (GO:0061512)3.59194584
37gamma-aminobutyric acid transport (GO:0015812)3.57509273
38regulation of excitatory postsynaptic membrane potential (GO:0060079)3.53648663
39postsynaptic membrane organization (GO:0001941)3.52203086
40transmission of nerve impulse (GO:0019226)3.52127736
41regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.51229630
42gamma-aminobutyric acid signaling pathway (GO:0007214)3.49951631
43synaptic vesicle endocytosis (GO:0048488)3.48587972
44long-term memory (GO:0007616)3.47135846
45regulation of dendritic spine morphogenesis (GO:0061001)3.43708291
46neurofilament cytoskeleton organization (GO:0060052)3.42667327
47presynaptic membrane assembly (GO:0097105)3.41203209
48positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.41187007
49neurotransmitter transport (GO:0006836)3.41109748
50cell migration in hindbrain (GO:0021535)3.40774470
51regulation of postsynaptic membrane potential (GO:0060078)3.40671743
52dendrite morphogenesis (GO:0048813)3.40664971
53negative regulation of synaptic transmission, GABAergic (GO:0032229)3.39633653
54positive regulation of membrane potential (GO:0045838)3.39606480
55membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.39181015
56cellular potassium ion homeostasis (GO:0030007)3.34879516
57regulation of synaptic plasticity (GO:0048167)3.28394437
58long-term synaptic potentiation (GO:0060291)3.27934873
59regulation of neurotransmitter secretion (GO:0046928)3.23335465
60activation of protein kinase A activity (GO:0034199)3.23021347
61regulation of vesicle fusion (GO:0031338)3.21122294
62regulation of synaptic transmission, glutamatergic (GO:0051966)3.21052880
63presynaptic membrane organization (GO:0097090)3.20488515
64synapse assembly (GO:0007416)3.19072302
65cerebral cortex radially oriented cell migration (GO:0021799)3.18634044
66startle response (GO:0001964)3.17944533
67G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.14752119
68behavioral fear response (GO:0001662)3.10768607
69behavioral defense response (GO:0002209)3.10768607
70regulation of neurotransmitter levels (GO:0001505)3.10003132
71mechanosensory behavior (GO:0007638)3.08665114
72auditory behavior (GO:0031223)3.07767706
73regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.07660730
74neuromuscular process controlling balance (GO:0050885)3.06048302
75innervation (GO:0060384)3.05286047
76cerebellar Purkinje cell differentiation (GO:0021702)3.05133243
77positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.04583824
78cerebellar granule cell differentiation (GO:0021707)3.03565795
79short-term memory (GO:0007614)3.03531514
80positive regulation of synaptic transmission, GABAergic (GO:0032230)3.02579411
81behavioral response to nicotine (GO:0035095)3.02300058
82establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.01988339
83mitochondrion transport along microtubule (GO:0047497)3.01988339
84negative regulation of microtubule polymerization (GO:0031115)3.01886371
85negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.01053078
86membrane depolarization during action potential (GO:0086010)3.01009478
87membrane depolarization (GO:0051899)3.00653391
88central nervous system projection neuron axonogenesis (GO:0021952)2.99782190
89regulation of action potential (GO:0098900)2.99738984
90learning (GO:0007612)2.99168443
91regulation of dendritic spine development (GO:0060998)2.98344633
92response to auditory stimulus (GO:0010996)2.96597303
93glycosphingolipid biosynthetic process (GO:0006688)2.96556164
94regulation of neurotransmitter transport (GO:0051588)2.96133967
95membrane hyperpolarization (GO:0060081)2.96010312
96positive regulation of mitochondrial fission (GO:0090141)2.95985242
97synapse organization (GO:0050808)2.95766612
98fear response (GO:0042596)2.95318895
99response to histamine (GO:0034776)2.94121373
100detection of calcium ion (GO:0005513)2.93365019
101positive regulation of dendritic spine development (GO:0060999)2.93211839
102positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.89919821
103negative regulation of dendrite development (GO:2000171)2.88963339
104sodium ion export (GO:0071436)2.88271567
105regulation of synapse maturation (GO:0090128)2.88175187
106positive regulation of action potential (GO:0045760)2.88155618
107neuronal ion channel clustering (GO:0045161)2.87677373
108positive regulation of dendritic spine morphogenesis (GO:0061003)2.87588559
109synaptic transmission (GO:0007268)2.87442066
110* organelle transport along microtubule (GO:0072384)2.87122430
111positive regulation of synapse assembly (GO:0051965)2.87012776
112social behavior (GO:0035176)2.86100135
113intraspecies interaction between organisms (GO:0051703)2.86100135
114dendritic spine organization (GO:0097061)2.85984166
115positive regulation of neurotransmitter secretion (GO:0001956)2.84966954
116mating behavior (GO:0007617)2.84711131
117central nervous system neuron axonogenesis (GO:0021955)2.83224252
118pyrimidine nucleobase catabolic process (GO:0006208)2.82696326
119calcium ion-dependent exocytosis (GO:0017156)2.82442956
120adult walking behavior (GO:0007628)2.69942158
121neuronal action potential (GO:0019228)2.69289087
122negative regulation of cytosolic calcium ion concentration (GO:0051481)2.68951960
123retinal ganglion cell axon guidance (GO:0031290)2.68511729
124regulation of cilium movement (GO:0003352)2.68192898
125regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.67773000
126regulation of feeding behavior (GO:0060259)2.61445422
127C4-dicarboxylate transport (GO:0015740)2.60135113
128regulation of cell communication by electrical coupling (GO:0010649)2.58916347
129serotonin metabolic process (GO:0042428)2.58675297
130dopamine biosynthetic process (GO:0042416)2.56226238
131regulation of voltage-gated calcium channel activity (GO:1901385)2.55162033
132adult behavior (GO:0030534)2.54804820
133hippocampus development (GO:0021766)2.54793309
134regulation of respiratory system process (GO:0044065)2.54141080
135substrate-independent telencephalic tangential migration (GO:0021826)2.53638902
136substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.53638902

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.09259757
2GBX2_23144817_ChIP-Seq_PC3_Human3.68565718
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.05282819
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.97333158
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.91049830
6REST_21632747_ChIP-Seq_MESCs_Mouse2.66277591
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.59155546
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.59155546
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.53263258
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.52377198
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.51016103
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.43806905
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.41686822
14SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.38601367
15MTF2_20144788_ChIP-Seq_MESCs_Mouse2.38220936
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.28340791
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.21153370
18NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.20762409
19DROSHA_22980978_ChIP-Seq_HELA_Human2.19709877
20EZH2_27294783_Chip-Seq_ESCs_Mouse2.17507440
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.16900181
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.13190178
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.12824125
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.11632565
25REST_18959480_ChIP-ChIP_MESCs_Mouse2.11274097
26TAF15_26573619_Chip-Seq_HEK293_Human2.08589785
27CTBP2_25329375_ChIP-Seq_LNCAP_Human2.07033049
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.01199215
29RBPJ_22232070_ChIP-Seq_NCS_Mouse1.96946421
30AR_21572438_ChIP-Seq_LNCaP_Human1.94466938
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.84145835
32ZFP57_27257070_Chip-Seq_ESCs_Mouse1.72571240
33IKZF1_21737484_ChIP-ChIP_HCT116_Human1.71111488
34SMAD4_21799915_ChIP-Seq_A2780_Human1.70454773
35ZNF274_21170338_ChIP-Seq_K562_Hela1.67159261
36* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.62167686
37MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58143150
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.57572034
39MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.57444522
40P300_19829295_ChIP-Seq_ESCs_Human1.54338309
41HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.52807492
42CBX2_27304074_Chip-Seq_ESCs_Mouse1.52426653
43EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49207558
44EWS_26573619_Chip-Seq_HEK293_Human1.44617738
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.44284473
46BMI1_23680149_ChIP-Seq_NPCS_Mouse1.43321742
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.40988499
48OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37981088
49ERG_21242973_ChIP-ChIP_JURKAT_Human1.37524172
50PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.37498444
51* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.36920752
52SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36869139
53RNF2_27304074_Chip-Seq_NSC_Mouse1.35804859
54RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.35011838
55SOX2_21211035_ChIP-Seq_LN229_Gbm1.34874608
56TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34178986
57NR3C1_23031785_ChIP-Seq_PC12_Mouse1.33828405
58AR_25329375_ChIP-Seq_VCAP_Human1.32086411
59FLI1_27457419_Chip-Seq_LIVER_Mouse1.31080962
60POU3F2_20337985_ChIP-ChIP_501MEL_Human1.29693869
61FUS_26573619_Chip-Seq_HEK293_Human1.28937013
62* RING1B_27294783_Chip-Seq_ESCs_Mouse1.28444329
63FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.25503342
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25403190
65CBP_20019798_ChIP-Seq_JUKART_Human1.25403190
66IGF1R_20145208_ChIP-Seq_DFB_Human1.25233678
67STAT3_23295773_ChIP-Seq_U87_Human1.24813454
68BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.24220552
69SALL1_21062744_ChIP-ChIP_HESCs_Human1.24179315
70PIAS1_25552417_ChIP-Seq_VCAP_Human1.21481537
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20927208
72BCAT_22108803_ChIP-Seq_LS180_Human1.20531607
73* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.18082082
74VDR_22108803_ChIP-Seq_LS180_Human1.17748832
75TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.16231120
76GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15692068
77* TAL1_26923725_Chip-Seq_HPCs_Mouse1.15636385
78PCGF2_27294783_Chip-Seq_ESCs_Mouse1.15193544
79* AR_19668381_ChIP-Seq_PC3_Human1.14548764
80CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14262095
81* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13380861
82RING1B_27294783_Chip-Seq_NPCs_Mouse1.13230425
83AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12760046
84SMAD_19615063_ChIP-ChIP_OVARY_Human1.11080746
85TCF4_23295773_ChIP-Seq_U87_Human1.10493277
86ARNT_22903824_ChIP-Seq_MCF-7_Human1.08229132
87YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07311732
88KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06091665
89KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.05975209
90* P53_22387025_ChIP-Seq_ESCs_Mouse1.05860362
91MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05763595
92* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.05277949
93FLI1_21867929_ChIP-Seq_TH2_Mouse1.04848628
94CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.04419526
95* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04403733
96ER_23166858_ChIP-Seq_MCF-7_Human1.04175379
97* P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03699821
98RUNX2_22187159_ChIP-Seq_PCA_Human1.03638115
99ZNF217_24962896_ChIP-Seq_MCF-7_Human1.03334821
100* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01730634
101AHR_22903824_ChIP-Seq_MCF-7_Human1.01354996
102PRDM14_20953172_ChIP-Seq_ESCs_Human1.01262645
103* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.00850449
104JUN_21703547_ChIP-Seq_K562_Human1.00316253
105SMAD3_21741376_ChIP-Seq_ESCs_Human1.00263304
106* E2F1_18555785_Chip-Seq_ESCs_Mouse0.99947860
107TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99495388
108NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99371695
109KDM2B_26808549_Chip-Seq_REH_Human0.98564816
110TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98222035
111POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.98222035
112WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.97245587
113TP53_22573176_ChIP-Seq_HFKS_Human0.96997961
114ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.95106312
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93326298
116* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92893903
117TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.91596458
118TP53_18474530_ChIP-ChIP_U2OS_Human0.91097884
119DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90530521
120ZFP281_18757296_ChIP-ChIP_E14_Mouse0.89714121
121* SMAD4_21741376_ChIP-Seq_HESCs_Human0.89375047
122TP53_16413492_ChIP-PET_HCT116_Human0.88875084
123* NANOG_18555785_Chip-Seq_ESCs_Mouse0.88476161
124* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.88439123

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.81690091
2MP0003880_abnormal_central_pattern4.88269694
3MP0003635_abnormal_synaptic_transmissio3.93649806
4MP0004270_analgesia3.90398036
5MP0002063_abnormal_learning/memory/cond3.21489390
6MP0009745_abnormal_behavioral_response3.20986348
7MP0001968_abnormal_touch/_nociception3.04687813
8MP0002064_seizures2.97225836
9MP0009046_muscle_twitch2.94302609
10MP0005423_abnormal_somatic_nervous2.79829659
11MP0002734_abnormal_mechanical_nocicepti2.75505311
12MP0002572_abnormal_emotion/affect_behav2.69696295
13MP0002102_abnormal_ear_morphology2.49529454
14MP0002272_abnormal_nervous_system2.49197777
15MP0002735_abnormal_chemical_nociception2.48433384
16MP0001486_abnormal_startle_reflex2.43401515
17MP0002736_abnormal_nociception_after2.41436592
18MP0000778_abnormal_nervous_system2.27434845
19MP0001440_abnormal_grooming_behavior2.23464890
20MP0002733_abnormal_thermal_nociception2.17065179
21MP0006276_abnormal_autonomic_nervous2.15587033
22MP0002822_catalepsy2.11136187
23MP0001501_abnormal_sleep_pattern2.05523967
24MP0002184_abnormal_innervation2.02565544
25MP0001970_abnormal_pain_threshold2.01088688
26MP0002067_abnormal_sensory_capabilities1.98806631
27MP0003329_amyloid_beta_deposits1.88434412
28MP0001984_abnormal_olfaction1.83095356
29MP0004811_abnormal_neuron_physiology1.78092112
30MP0009780_abnormal_chondrocyte_physiolo1.77233325
31MP0002557_abnormal_social/conspecific_i1.77093039
32MP0004924_abnormal_behavior1.76964945
33MP0005386_behavior/neurological_phenoty1.76964945
34MP0004858_abnormal_nervous_system1.75712105
35MP0008569_lethality_at_weaning1.64415261
36* MP0000955_abnormal_spinal_cord1.62008941
37MP0001529_abnormal_vocalization1.59774886
38MP0002882_abnormal_neuron_morphology1.51726436
39MP0003122_maternal_imprinting1.49636802
40MP0008877_abnormal_DNA_methylation1.42880331
41MP0004885_abnormal_endolymph1.41517033
42MP0002909_abnormal_adrenal_gland1.41346797
43* MP0002066_abnormal_motor_capabilities/c1.41271333
44MP0001905_abnormal_dopamine_level1.37247161
45MP0005646_abnormal_pituitary_gland1.37182212
46MP0005645_abnormal_hypothalamus_physiol1.31152342
47MP0003787_abnormal_imprinting1.28556583
48MP0003879_abnormal_hair_cell1.26573257
49MP0001188_hyperpigmentation1.21469313
50MP0004142_abnormal_muscle_tone1.20706174
51MP0001502_abnormal_circadian_rhythm1.20600374
52* MP0002152_abnormal_brain_morphology1.20356613
53MP0003633_abnormal_nervous_system1.14763902
54MP0000751_myopathy1.12106318
55MP0004145_abnormal_muscle_electrophysio1.09994553
56MP0004742_abnormal_vestibular_system1.06735055
57MP0005253_abnormal_eye_physiology1.04851547
58MP0003631_nervous_system_phenotype1.04029621
59MP0005551_abnormal_eye_electrophysiolog1.03536221
60MP0005499_abnormal_olfactory_system1.03476754
61MP0005394_taste/olfaction_phenotype1.03476754
62MP0002837_dystrophic_cardiac_calcinosis1.03170461
63MP0002229_neurodegeneration0.99476825
64MP0010386_abnormal_urinary_bladder0.95060277
65MP0004133_heterotaxia0.93960436
66MP0003634_abnormal_glial_cell0.92678641
67* MP0002752_abnormal_somatic_nervous0.91648688
68MP0000569_abnormal_digit_pigmentation0.91639207
69MP0001986_abnormal_taste_sensitivity0.90013886
70MP0000631_abnormal_neuroendocrine_gland0.88763594
71MP0002069_abnormal_eating/drinking_beha0.87952029
72MP0001963_abnormal_hearing_physiology0.87189024
73MP0005623_abnormal_meninges_morphology0.85958565
74MP0002234_abnormal_pharynx_morphology0.85144837
75MP0005410_abnormal_fertilization0.84971196
76MP0004085_abnormal_heartbeat0.83999403
77MP0000013_abnormal_adipose_tissue0.82897657
78MP0003632_abnormal_nervous_system0.81037756
79MP0004233_abnormal_muscle_weight0.79740346
80MP0004147_increased_porphyrin_level0.79260109
81MP0001177_atelectasis0.79127925
82MP0008872_abnormal_physiological_respon0.78751370
83MP0000920_abnormal_myelination0.77669553
84* MP0003861_abnormal_nervous_system0.76551503
85MP0000604_amyloidosis0.76236536
86MP0001299_abnormal_eye_distance/0.76166836
87MP0003938_abnormal_ear_development0.73765235
88MP0000049_abnormal_middle_ear0.73472244
89MP0005409_darkened_coat_color0.72868563
90MP0005248_abnormal_Harderian_gland0.72781327
91MP0002638_abnormal_pupillary_reflex0.72322444
92MP0004215_abnormal_myocardial_fiber0.72079757
93MP0002653_abnormal_ependyma_morphology0.71900351
94MP0004043_abnormal_pH_regulation0.70304808
95MP0001485_abnormal_pinna_reflex0.69913870
96MP0005367_renal/urinary_system_phenotyp0.69606349
97MP0000516_abnormal_urinary_system0.69606349
98MP0003137_abnormal_impulse_conducting0.68627244
99MP0008874_decreased_physiological_sensi0.68497192
100MP0005195_abnormal_posterior_eye0.67459895
101MP0005535_abnormal_body_temperature0.67210028
102MP0005187_abnormal_penis_morphology0.66578837
103MP0004484_altered_response_of0.65622797
104MP0002090_abnormal_vision0.65331074
105MP0002928_abnormal_bile_duct0.64183770
106MP0008995_early_reproductive_senescence0.63565563
107MP0003283_abnormal_digestive_organ0.63091998
108MP0006072_abnormal_retinal_apoptosis0.62373824
109MP0000566_synostosis0.62127550
110MP0001943_abnormal_respiration0.62123544
111MP0000647_abnormal_sebaceous_gland0.61594195
112MP0001664_abnormal_digestion0.60268834
113MP0003690_abnormal_glial_cell0.59585781
114MP0005171_absent_coat_pigmentation0.58966264
115MP0000026_abnormal_inner_ear0.58739585
116MP0001348_abnormal_lacrimal_gland0.57703530
117MP0002751_abnormal_autonomic_nervous0.57402935
118MP0003121_genomic_imprinting0.57002159
119MP0008789_abnormal_olfactory_epithelium0.54290757

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.77964823
2Myokymia (HP:0002411)6.02205858
3Focal seizures (HP:0007359)5.27334185
4Visual hallucinations (HP:0002367)4.80893274
5Epileptic encephalopathy (HP:0200134)4.59641903
6Atonic seizures (HP:0010819)4.43168622
7Progressive cerebellar ataxia (HP:0002073)3.94849549
8Febrile seizures (HP:0002373)3.89637119
9Absence seizures (HP:0002121)3.82029771
10Supranuclear gaze palsy (HP:0000605)3.67199229
11Dialeptic seizures (HP:0011146)3.52867471
12Broad-based gait (HP:0002136)3.52727368
13Generalized tonic-clonic seizures (HP:0002069)3.40093768
14Action tremor (HP:0002345)3.38903819
15Ankle clonus (HP:0011448)3.32881961
16Hyperventilation (HP:0002883)3.30943210
17Mutism (HP:0002300)3.20033197
18Termporal pattern (HP:0011008)3.07939747
19Insidious onset (HP:0003587)3.07939747
20Abnormality of the corticospinal tract (HP:0002492)3.07015120
21Impaired vibration sensation in the lower limbs (HP:0002166)3.04372717
22Limb dystonia (HP:0002451)3.03477163
23Amblyopia (HP:0000646)2.97990137
24Nephrogenic diabetes insipidus (HP:0009806)2.97595336
25Poor eye contact (HP:0000817)2.94234967
26Drooling (HP:0002307)2.93271428
27Excessive salivation (HP:0003781)2.93271428
28Cerebral inclusion bodies (HP:0100314)2.92120096
29Urinary bladder sphincter dysfunction (HP:0002839)2.87299311
30Truncal ataxia (HP:0002078)2.84850675
31Neurofibrillary tangles (HP:0002185)2.82174200
32Urinary urgency (HP:0000012)2.81307736
33Dysdiadochokinesis (HP:0002075)2.80296950
34Progressive inability to walk (HP:0002505)2.80014982
35Gaze-evoked nystagmus (HP:0000640)2.78734764
36Abnormal eating behavior (HP:0100738)2.77958651
37Depression (HP:0000716)2.75227422
38Dysmetria (HP:0001310)2.72071778
39Abnormality of the labia minora (HP:0012880)2.70330216
40Pachygyria (HP:0001302)2.64102297
41Impaired social interactions (HP:0000735)2.63936744
42Abnormal social behavior (HP:0012433)2.63936744
43Spastic gait (HP:0002064)2.63666238
44Anxiety (HP:0000739)2.62662618
45Amyotrophic lateral sclerosis (HP:0007354)2.61321216
46Chronic hepatic failure (HP:0100626)2.60977295
47Molar tooth sign on MRI (HP:0002419)2.60176179
48Abnormality of midbrain morphology (HP:0002418)2.60176179
49Genital tract atresia (HP:0001827)2.58299450
50Pheochromocytoma (HP:0002666)2.57933489
51Polyphagia (HP:0002591)2.56059281
52Papilledema (HP:0001085)2.54690191
53Hemiparesis (HP:0001269)2.50257265
54Epileptiform EEG discharges (HP:0011182)2.50166662
55Hepatoblastoma (HP:0002884)2.46405988
56Spastic tetraplegia (HP:0002510)2.46389440
57Vaginal atresia (HP:0000148)2.45913844
58Fetal akinesia sequence (HP:0001989)2.45127881
59EEG with generalized epileptiform discharges (HP:0011198)2.41949189
60Absent speech (HP:0001344)2.41537595
61Postural instability (HP:0002172)2.41106285
62True hermaphroditism (HP:0010459)2.39640772
63Nephronophthisis (HP:0000090)2.39520163
64Abnormality of binocular vision (HP:0011514)2.38809460
65Diplopia (HP:0000651)2.38809460
66Inability to walk (HP:0002540)2.35253279
67Pancreatic fibrosis (HP:0100732)2.35116303
68Genetic anticipation (HP:0003743)2.34032969
69Abnormality of the lower motor neuron (HP:0002366)2.33593484
70Gait imbalance (HP:0002141)2.32750755
71Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.32294720
72Degeneration of the lateral corticospinal tracts (HP:0002314)2.32294720
73Hypothermia (HP:0002045)2.30897193
74Torticollis (HP:0000473)2.30384620
75Hypsarrhythmia (HP:0002521)2.28051220
76Lower limb muscle weakness (HP:0007340)2.27872368
77Akinesia (HP:0002304)2.26296265
78Neuroendocrine neoplasm (HP:0100634)2.22155785
79Scanning speech (HP:0002168)2.19753124
80Impaired smooth pursuit (HP:0007772)2.19339069
81Megalencephaly (HP:0001355)2.16791585
82Bradykinesia (HP:0002067)2.16761337
83Pancreatic cysts (HP:0001737)2.16704522
84Focal dystonia (HP:0004373)2.10958584
85Dynein arm defect of respiratory motile cilia (HP:0012255)2.10800891
86Absent/shortened dynein arms (HP:0200106)2.10800891
87Stereotypic behavior (HP:0000733)2.08631234
88Poor coordination (HP:0002370)2.07714782
89Muscular hypotonia of the trunk (HP:0008936)2.07535206
90Intention tremor (HP:0002080)2.06170983
91Aplasia/Hypoplasia of the brainstem (HP:0007362)2.05090564
92Hypoplasia of the brainstem (HP:0002365)2.05090564
93Poor suck (HP:0002033)2.03440069
94Generalized myoclonic seizures (HP:0002123)2.00060452
95Specific learning disability (HP:0001328)1.99218653
96Atrophy/Degeneration involving motor neurons (HP:0007373)1.99127629
97Inappropriate behavior (HP:0000719)1.98516313
98Occipital encephalocele (HP:0002085)1.97886285
99Agitation (HP:0000713)1.97593771
100Status epilepticus (HP:0002133)1.95743794
101Abnormality of ocular smooth pursuit (HP:0000617)1.94469683
102Abnormality of salivation (HP:0100755)1.94090267
103Blue irides (HP:0000635)1.91401094
104Aplasia/Hypoplasia of the tibia (HP:0005772)1.90919871
105Postaxial hand polydactyly (HP:0001162)1.90612444
106Abnormal respiratory motile cilium morphology (HP:0005938)1.90430764
107Abnormal respiratory epithelium morphology (HP:0012253)1.90430764
108Hypoplasia of the corpus callosum (HP:0002079)1.89981149
109Craniofacial dystonia (HP:0012179)1.89731475
110Epidermoid cyst (HP:0200040)1.88714687
111Abnormality of the renal medulla (HP:0100957)1.87875652
112Abnormal respiratory motile cilium physiology (HP:0012261)1.87392281
113Narrow forehead (HP:0000341)1.87139712
114Sleep apnea (HP:0010535)1.87089162
115Impaired vibratory sensation (HP:0002495)1.85937564
116Gait ataxia (HP:0002066)1.84584724
117Type II lissencephaly (HP:0007260)1.84525301
118Hypoventilation (HP:0002791)1.83786911
119Optic nerve hypoplasia (HP:0000609)1.83690410
120Morphological abnormality of the pyramidal tract (HP:0002062)1.83042177
121Lissencephaly (HP:0001339)1.82498223
122Tubulointerstitial nephritis (HP:0001970)1.81323548
123Delusions (HP:0000746)1.80486347
124Failure to thrive in infancy (HP:0001531)1.79906684
125Aplasia/Hypoplasia of the lens (HP:0008063)1.79569500
126Esotropia (HP:0000565)1.79450886
127Short tibia (HP:0005736)1.77815196
128Paraplegia (HP:0010550)1.76984875
129Protruding tongue (HP:0010808)1.76294317
130Retinal dysplasia (HP:0007973)1.76168988
131Incomplete penetrance (HP:0003829)1.75125954
132Aqueductal stenosis (HP:0002410)1.74978464
133Dyskinesia (HP:0100660)1.73701266
134Split foot (HP:0001839)1.73195274
135Congenital primary aphakia (HP:0007707)1.72093988
136Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.71965162
137Clonus (HP:0002169)1.71544618
138Neuronal loss in central nervous system (HP:0002529)1.71240194
139Thyroid-stimulating hormone excess (HP:0002925)1.70609743
140Medial flaring of the eyebrow (HP:0010747)1.69905851
141Abnormal ciliary motility (HP:0012262)1.69617018
142Neoplasm of the peripheral nervous system (HP:0100007)1.69502896

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.40988519
2NTRK33.99734983
3MAP3K93.75126879
4EPHA43.59254722
5MAP3K43.16507153
6MAP2K72.64788506
7TRIM282.61452969
8* MINK12.54120347
9MAP3K122.35695031
10MAP4K22.33357383
11CASK2.32743631
12NTRK22.11884273
13PAK62.06520009
14PNCK2.05303864
15DAPK21.99838774
16MAP2K41.95209253
17FRK1.88349840
18NTRK11.80324234
19KSR21.75387725
20RIPK41.71372162
21PLK21.69516301
22KSR11.68288887
23MAPK131.62466185
24CSNK1A1L1.54720582
25TNIK1.49280582
26CDK51.48888127
27CSNK1G11.45082437
28EPHA31.43524811
29PRKD31.42599049
30PHKG21.41382435
31PHKG11.41382435
32CAMKK11.36763297
33GRK51.36639938
34CDK191.33500620
35LATS21.32767768
36ARAF1.27537014
37DAPK11.27435633
38SIK21.27124929
39PRKCG1.20035599
40UHMK11.17937500
41TYRO31.12608935
42DYRK31.11204176
43PRPF4B1.06198324
44CAMK2A1.04134044
45MAP3K20.99684226
46CDK140.99192399
47CSNK1G20.99069048
48CDK180.97108515
49OXSR10.93775261
50CDK150.92870335
51ADRBK20.91916325
52STK380.90959874
53CAMK2B0.90137436
54PAK30.88838731
55CAMKK20.87354436
56FES0.86733016
57PTK2B0.86517199
58RET0.82424085
59DYRK1A0.81164945
60CDK11A0.80413189
61INSRR0.79765943
62BCR0.79436856
63BCKDK0.77698526
64SGK2230.76998418
65SGK4940.76998418
66DYRK20.75008887
67STK110.71630501
68BMPR20.70428390
69PDK40.69029338
70PDK30.69029338
71ERBB30.68909363
72STK390.67443381
73CAMK40.63587904
74LIMK10.63174070
75MARK20.61112542
76LMTK20.60440161
77RAF10.59461109
78PRKCE0.59155517
79CAMK10.59114115
80FGFR20.59074220
81PRKCZ0.59047937
82CAMK2D0.58637191
83MAP3K130.57958653
84SGK10.56646826
85GRK10.56592049
86EPHB20.56514794
87FER0.56194003
88NME10.55928120
89BMPR1B0.54732912
90FGR0.54684496
91CCNB10.54512049
92WNK30.51904996
93SIK30.51891132
94PRKG10.51862840
95OBSCN0.51632585
96CSNK1G30.51543652
97ROCK20.50023073
98PRKACA0.49683894
99CAMK2G0.49463136
100DYRK1B0.49331962
101PKN10.48973560
102SGK20.48029742
103PRKCH0.47420821
104WNK10.47044085
105SCYL20.46209845
106RPS6KA40.45991746
107PINK10.45935300
108WNK40.45414353
109CSNK1D0.44725450
110CAMK1G0.44383906
111FYN0.43532648
112MAP3K60.43514447
113TAOK10.42987779
114CSNK1A10.42964742
115SGK30.42277332
116PDK10.41269931
117PDPK10.40034005
118ALK0.39611073
119RPS6KA30.39460246
120MAPK100.39301975
121MAP2K10.39017101
122RPS6KA20.38995176
123PRKACB0.35192960
124ADRBK10.34518551
125CSNK1E0.32318927
126TSSK60.32007361
127SRPK10.30474327
128PRKAA10.28528024
129PRKCB0.27313714
130PRKCA0.27061703

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.67992471
2Synaptic vesicle cycle_Homo sapiens_hsa047213.31100169
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.68248837
4Long-term potentiation_Homo sapiens_hsa047202.62501815
5GABAergic synapse_Homo sapiens_hsa047272.61425936
6Circadian entrainment_Homo sapiens_hsa047132.60820698
7Olfactory transduction_Homo sapiens_hsa047402.59765480
8Glutamatergic synapse_Homo sapiens_hsa047242.52829880
9Morphine addiction_Homo sapiens_hsa050322.40671006
10Amphetamine addiction_Homo sapiens_hsa050312.40504846
11Dopaminergic synapse_Homo sapiens_hsa047282.28577587
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.26551826
13Salivary secretion_Homo sapiens_hsa049702.04783889
14Cholinergic synapse_Homo sapiens_hsa047251.89441327
15Insulin secretion_Homo sapiens_hsa049111.87807304
16Taste transduction_Homo sapiens_hsa047421.83528913
17Serotonergic synapse_Homo sapiens_hsa047261.82635717
18Renin secretion_Homo sapiens_hsa049241.80254164
19Gastric acid secretion_Homo sapiens_hsa049711.79027537
20Long-term depression_Homo sapiens_hsa047301.76927697
21Collecting duct acid secretion_Homo sapiens_hsa049661.74942908
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.67538550
23Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.65717542
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.64097116
25Cocaine addiction_Homo sapiens_hsa050301.62731399
26Oxytocin signaling pathway_Homo sapiens_hsa049211.60957610
27Butanoate metabolism_Homo sapiens_hsa006501.53449477
28Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.51429104
29Protein export_Homo sapiens_hsa030601.50638562
30Axon guidance_Homo sapiens_hsa043601.49659214
31Calcium signaling pathway_Homo sapiens_hsa040201.48588001
32Gap junction_Homo sapiens_hsa045401.47705132
33GnRH signaling pathway_Homo sapiens_hsa049121.40433732
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.30342937
35Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.24378857
36Cardiac muscle contraction_Homo sapiens_hsa042601.21112119
37Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.18538458
38Estrogen signaling pathway_Homo sapiens_hsa049151.18241644
39Vibrio cholerae infection_Homo sapiens_hsa051101.17864768
40Phototransduction_Homo sapiens_hsa047441.17183185
41cAMP signaling pathway_Homo sapiens_hsa040241.14875808
42Melanogenesis_Homo sapiens_hsa049161.07618358
43Glioma_Homo sapiens_hsa052141.07020104
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06277000
45ErbB signaling pathway_Homo sapiens_hsa040121.06083518
46Phosphatidylinositol signaling system_Homo sapiens_hsa040701.05554630
47Oocyte meiosis_Homo sapiens_hsa041141.02672134
48cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00574882
49Type II diabetes mellitus_Homo sapiens_hsa049300.99235535
50Steroid biosynthesis_Homo sapiens_hsa001000.96885772
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.91002986
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.88744269
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.88623255
54Regulation of autophagy_Homo sapiens_hsa041400.88569557
55Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.86942677
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86829280
57Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.83327335
58Dorso-ventral axis formation_Homo sapiens_hsa043200.83209123
59Alzheimers disease_Homo sapiens_hsa050100.81183317
60Phospholipase D signaling pathway_Homo sapiens_hsa040720.78791805
61Pancreatic secretion_Homo sapiens_hsa049720.76468024
62Nitrogen metabolism_Homo sapiens_hsa009100.75973299
63Thyroid hormone synthesis_Homo sapiens_hsa049180.74659856
64Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.74024613
65Oxidative phosphorylation_Homo sapiens_hsa001900.72693670
66Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.72578086
67Dilated cardiomyopathy_Homo sapiens_hsa054140.70999911
68Choline metabolism in cancer_Homo sapiens_hsa052310.70051307
69beta-Alanine metabolism_Homo sapiens_hsa004100.69229704
70MAPK signaling pathway_Homo sapiens_hsa040100.69216010
71VEGF signaling pathway_Homo sapiens_hsa043700.65396183
72Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65154861
73Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.64386610
74Glucagon signaling pathway_Homo sapiens_hsa049220.63665444
75Ras signaling pathway_Homo sapiens_hsa040140.63360738
76Alcoholism_Homo sapiens_hsa050340.62364216
77Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.61175343
78Neurotrophin signaling pathway_Homo sapiens_hsa047220.61036967
79Propanoate metabolism_Homo sapiens_hsa006400.60813613
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.60300532
81Sphingolipid signaling pathway_Homo sapiens_hsa040710.58791364
82Parkinsons disease_Homo sapiens_hsa050120.57966701
83Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.56999897
84Ether lipid metabolism_Homo sapiens_hsa005650.56173996
85Renal cell carcinoma_Homo sapiens_hsa052110.55500802
86Wnt signaling pathway_Homo sapiens_hsa043100.55387779
87Maturity onset diabetes of the young_Homo sapiens_hsa049500.54991983
88Peroxisome_Homo sapiens_hsa041460.54963766
89Rap1 signaling pathway_Homo sapiens_hsa040150.53754363
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.53274084
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53088132
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.50842710
93Carbohydrate digestion and absorption_Homo sapiens_hsa049730.49916501
94Thyroid hormone signaling pathway_Homo sapiens_hsa049190.49848150
95Endometrial cancer_Homo sapiens_hsa052130.49572446
96Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.48604098
97Endocytosis_Homo sapiens_hsa041440.48376235
98Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.45271071
99Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.44897142
100Huntingtons disease_Homo sapiens_hsa050160.44680940
101mTOR signaling pathway_Homo sapiens_hsa041500.44592086
102Inositol phosphate metabolism_Homo sapiens_hsa005620.44091172
103Fatty acid elongation_Homo sapiens_hsa000620.42919581
104Linoleic acid metabolism_Homo sapiens_hsa005910.41500847
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40465978
106ABC transporters_Homo sapiens_hsa020100.40036876
107Colorectal cancer_Homo sapiens_hsa052100.39713058
108Insulin signaling pathway_Homo sapiens_hsa049100.39099976
109Prion diseases_Homo sapiens_hsa050200.38673037
110Primary bile acid biosynthesis_Homo sapiens_hsa001200.35715695
111Fatty acid biosynthesis_Homo sapiens_hsa000610.35465121
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.34960919
113Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.34951466
114Circadian rhythm_Homo sapiens_hsa047100.34926720
115African trypanosomiasis_Homo sapiens_hsa051430.34742285
116alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.33720522
117Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.33347334
118Type I diabetes mellitus_Homo sapiens_hsa049400.32271583
119Longevity regulating pathway - mammal_Homo sapiens_hsa042110.31974143
120Non-small cell lung cancer_Homo sapiens_hsa052230.31359970
121SNARE interactions in vesicular transport_Homo sapiens_hsa041300.31088889
122Tight junction_Homo sapiens_hsa045300.30413414
123Steroid hormone biosynthesis_Homo sapiens_hsa001400.30246898
124Hedgehog signaling pathway_Homo sapiens_hsa043400.30123078
125Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.29705817
126Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.28844607
127Hippo signaling pathway_Homo sapiens_hsa043900.28250196
128Ovarian steroidogenesis_Homo sapiens_hsa049130.27679118
129Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.27627263

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