KIFC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)6.92353103
2regulation of short-term neuronal synaptic plasticity (GO:0048172)6.88707101
3locomotory exploration behavior (GO:0035641)6.49147588
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)6.27640323
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.84930870
6synaptic vesicle docking involved in exocytosis (GO:0016081)5.84212696
7synaptic vesicle exocytosis (GO:0016079)5.77475849
8vocalization behavior (GO:0071625)5.71579699
9glutamate secretion (GO:0014047)5.69270879
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.54952749
11regulation of synaptic vesicle exocytosis (GO:2000300)5.33390831
12regulation of glutamate receptor signaling pathway (GO:1900449)5.26617948
13regulation of neuronal synaptic plasticity (GO:0048168)5.12095867
14regulation of long-term neuronal synaptic plasticity (GO:0048169)4.95872953
15neuronal action potential propagation (GO:0019227)4.86800939
16exploration behavior (GO:0035640)4.83474571
17ionotropic glutamate receptor signaling pathway (GO:0035235)4.82100632
18regulation of synaptic vesicle transport (GO:1902803)4.78398281
19neurotransmitter secretion (GO:0007269)4.76970288
20protein localization to synapse (GO:0035418)4.72693513
21regulation of synapse structural plasticity (GO:0051823)4.63454578
22dendritic spine morphogenesis (GO:0060997)4.47195816
23synaptic transmission, glutamatergic (GO:0035249)4.41487900
24layer formation in cerebral cortex (GO:0021819)4.39391258
25cytoskeletal anchoring at plasma membrane (GO:0007016)4.36301189
26long-term memory (GO:0007616)4.27488448
27gamma-aminobutyric acid transport (GO:0015812)4.27423429
28neurotransmitter-gated ion channel clustering (GO:0072578)4.24756467
29cerebellar granule cell differentiation (GO:0021707)4.23046910
30positive regulation of membrane potential (GO:0045838)4.16400233
31membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.15244683
32cellular potassium ion homeostasis (GO:0030007)4.15119198
33regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.14611595
34glutamate receptor signaling pathway (GO:0007215)4.10461930
35regulation of excitatory postsynaptic membrane potential (GO:0060079)4.07891839
36regulation of dendritic spine morphogenesis (GO:0061001)4.07861780
37proline transport (GO:0015824)4.07415186
38neuron-neuron synaptic transmission (GO:0007270)4.03978530
39sodium ion export (GO:0071436)4.02197571
40neuromuscular process controlling balance (GO:0050885)4.01207536
41neuron cell-cell adhesion (GO:0007158)3.94384797
42regulation of synaptic plasticity (GO:0048167)3.94368441
43regulation of ARF GTPase activity (GO:0032312)3.84729816
44regulation of postsynaptic membrane potential (GO:0060078)3.84289324
45amino acid import (GO:0043090)3.83044323
46neuromuscular process controlling posture (GO:0050884)3.78879347
47synaptic vesicle endocytosis (GO:0048488)3.78795893
48neurotransmitter transport (GO:0006836)3.77221586
49activation of protein kinase A activity (GO:0034199)3.71274930
50regulation of neurotransmitter secretion (GO:0046928)3.63505026
51regulation of synapse maturation (GO:0090128)3.63188018
52positive regulation of synapse maturation (GO:0090129)3.61848235
53positive regulation of neurotransmitter secretion (GO:0001956)3.59512388
54positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.58948476
55transmission of nerve impulse (GO:0019226)3.57298318
56glycine transport (GO:0015816)3.55171843
57regulation of neurotransmitter levels (GO:0001505)3.54027913
58positive regulation of neurotransmitter transport (GO:0051590)3.53367818
59mannose metabolic process (GO:0006013)3.52551625
60G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.52360264
61long-term synaptic potentiation (GO:0060291)3.49323782
62cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.48456232
63prepulse inhibition (GO:0060134)3.47965836
64regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.47560516
65positive regulation of synaptic transmission, GABAergic (GO:0032230)3.46282003
66semaphorin-plexin signaling pathway (GO:0071526)3.45247452
67positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.44769879
68auditory behavior (GO:0031223)3.44386635
69neuronal ion channel clustering (GO:0045161)3.41370041
70cerebellar Purkinje cell differentiation (GO:0021702)3.39183914
71L-amino acid import (GO:0043092)3.39165207
72dendritic spine organization (GO:0097061)3.39162665
73regulation of synaptic transmission, glutamatergic (GO:0051966)3.37397102
74regulation of neurotransmitter transport (GO:0051588)3.36822889
75cell communication by electrical coupling (GO:0010644)3.35512378
76regulation of dendritic spine development (GO:0060998)3.34252842
77positive regulation of dendritic spine development (GO:0060999)3.33002857
78regulation of vesicle fusion (GO:0031338)3.29488764
79response to auditory stimulus (GO:0010996)3.27188307
80regulation of ARF protein signal transduction (GO:0032012)3.26306882
81membrane depolarization (GO:0051899)3.26238591
82peptidyl-tyrosine autophosphorylation (GO:0038083)3.25322639
83membrane hyperpolarization (GO:0060081)3.24309125
84positive regulation of dendritic spine morphogenesis (GO:0061003)3.23507355
85neuromuscular process (GO:0050905)3.23453989
86activation of Rac GTPase activity (GO:0032863)3.21038037
87neuron recognition (GO:0008038)3.18366761
88gamma-aminobutyric acid signaling pathway (GO:0007214)3.17778156
89membrane depolarization during action potential (GO:0086010)3.17393904
90dendrite morphogenesis (GO:0048813)3.16117986
91negative regulation of dendrite morphogenesis (GO:0050774)3.15279105
92positive regulation of synaptic transmission (GO:0050806)3.14851599
93regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.14570757
94regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.13719081
95regulation of synaptic transmission (GO:0050804)3.13633194
96learning (GO:0007612)3.12567931
97signal complex assembly (GO:0007172)3.11873658
98negative regulation of erythrocyte differentiation (GO:0045647)3.09864463
99vesicle transport along microtubule (GO:0047496)3.08931747
100mitochondrion transport along microtubule (GO:0047497)3.08654781
101establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.08654781
102cell migration in hindbrain (GO:0021535)3.07077436
103establishment of mitochondrion localization (GO:0051654)3.03039142
104regulation of voltage-gated calcium channel activity (GO:1901385)3.00895554
105negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.00815586
106chemosensory behavior (GO:0007635)3.00424890
107synaptic transmission (GO:0007268)3.00141762
108negative regulation of synaptic transmission, GABAergic (GO:0032229)2.99836999
109intraspecies interaction between organisms (GO:0051703)2.96983103
110social behavior (GO:0035176)2.96983103
111axonal fasciculation (GO:0007413)2.96004226
112potassium ion import (GO:0010107)2.95949599
113potassium ion homeostasis (GO:0055075)2.95888514
114behavioral fear response (GO:0001662)2.94535581
115behavioral defense response (GO:0002209)2.94535581
116innervation (GO:0060384)2.93659204
117negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.93641081
118positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.93102003
119cell-cell junction maintenance (GO:0045217)2.83434787
120positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.80619218
121positive regulation of protein dephosphorylation (GO:0035307)2.80548477
122negative regulation of cell size (GO:0045792)2.77323594
123myelin maintenance (GO:0043217)2.73290600
124axon ensheathment in central nervous system (GO:0032291)2.70119476
125central nervous system myelination (GO:0022010)2.70119476
126positive regulation of dendrite development (GO:1900006)2.68749069
127mating behavior (GO:0007617)2.65481225
128dopamine receptor signaling pathway (GO:0007212)2.64375811
129positive regulation of Rap GTPase activity (GO:0032854)2.63344313
130endothelial cell chemotaxis (GO:0035767)2.60524285
131regulation of clathrin-mediated endocytosis (GO:2000369)2.55339146
132cerebellar Purkinje cell layer development (GO:0021680)2.52733462
133dicarboxylic acid transport (GO:0006835)2.52716985
134protein targeting to plasma membrane (GO:0072661)2.49207463
135cellular sodium ion homeostasis (GO:0006883)2.47857580
136vesicle docking involved in exocytosis (GO:0006904)2.47840132
137postsynaptic membrane organization (GO:0001941)2.47296639
138adherens junction assembly (GO:0034333)2.47286009
139protein retention in ER lumen (GO:0006621)2.45311258
140protein localization to endosome (GO:0036010)2.45111379

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.99353737
2RARB_27405468_Chip-Seq_BRAIN_Mouse3.24041015
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.09929874
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.01747863
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.00554292
6REST_21632747_ChIP-Seq_MESCs_Mouse2.97939559
7DROSHA_22980978_ChIP-Seq_HELA_Human2.92016671
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.78779922
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.78779922
10GBX2_23144817_ChIP-Seq_PC3_Human2.77166233
11TP63_17297297_ChIP-ChIP_HaCaT_Human2.74576447
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.70937278
13MTF2_20144788_ChIP-Seq_MESCs_Mouse2.59596240
14EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.59452366
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.58877952
16SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.52926925
17REST_18959480_ChIP-ChIP_MESCs_Mouse2.50652388
18MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.49336513
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.43745429
20ESR2_21235772_ChIP-Seq_MCF-7_Human2.42172012
21SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.39916730
22IKZF1_21737484_ChIP-ChIP_HCT116_Human2.39188509
23EZH2_27304074_Chip-Seq_ESCs_Mouse2.38498773
24TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.37892704
25SUZ12_27294783_Chip-Seq_ESCs_Mouse2.37403496
26EZH2_27294783_Chip-Seq_ESCs_Mouse2.27089169
27RARG_19884340_ChIP-ChIP_MEFs_Mouse2.24717222
28RNF2_27304074_Chip-Seq_ESCs_Mouse2.23954076
29KDM2B_26808549_Chip-Seq_DND41_Human2.14110907
30CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.11992482
31KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.10051519
32EED_16625203_ChIP-ChIP_MESCs_Mouse2.09380621
33RACK7_27058665_Chip-Seq_MCF-7_Human2.09004469
34* ERG_21242973_ChIP-ChIP_JURKAT_Human2.00260809
35NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.94604786
36TCF7_22412390_ChIP-Seq_EML_Mouse1.92601977
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.86841624
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.86212201
39VDR_21846776_ChIP-Seq_THP-1_Human1.83193697
40SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.81748131
41* P68_20966046_ChIP-Seq_HELA_Human1.79627108
42AR_21572438_ChIP-Seq_LNCaP_Human1.72411657
43NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.64887151
44CREB1_26743006_Chip-Seq_LNCaP_Human1.64628553
45RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.63513611
46TET1_21451524_ChIP-Seq_MESCs_Mouse1.62777761
47DNAJC2_21179169_ChIP-ChIP_NT2_Human1.61367340
48UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.60419554
49CTCF_27219007_Chip-Seq_ERYTHROID_Human1.53668078
50ZFP281_18757296_ChIP-ChIP_E14_Mouse1.52581665
51KDM2B_26808549_Chip-Seq_K562_Human1.49827907
52ESR1_21235772_ChIP-Seq_MCF-7_Human1.46959869
53* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.46492536
54SA1_27219007_Chip-Seq_ERYTHROID_Human1.46072082
55* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.45603411
56RING1B_27294783_Chip-Seq_ESCs_Mouse1.44420162
57GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.43664333
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42902960
59SRY_22984422_ChIP-ChIP_TESTIS_Rat1.42551512
60ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.40982516
61EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.40264909
62CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.39199997
63MYC_22102868_ChIP-Seq_BL_Human1.38222997
64NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.33272474
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.31766455
66RUNX1_27514584_Chip-Seq_MCF-7_Human1.30975976
67TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.30829735
68SMAD4_21799915_ChIP-Seq_A2780_Human1.30341689
69WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.27646245
70GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.26813141
71WT1_25993318_ChIP-Seq_PODOCYTE_Human1.26798027
72RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.25830077
73CTBP1_25329375_ChIP-Seq_LNCAP_Human1.24820399
74KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.24449319
75RING1B_27294783_Chip-Seq_NPCs_Mouse1.22284070
76AR_19668381_ChIP-Seq_PC3_Human1.21246063
77ZFP281_27345836_Chip-Seq_ESCs_Mouse1.21209088
78SOX2_21211035_ChIP-Seq_LN229_Gbm1.20367254
79CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.19922164
80MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.18801882
81P300_27058665_Chip-Seq_ZR-75-30cells_Human1.17392116
82ELF1_20517297_ChIP-Seq_JURKAT_Human1.15915817
83ZNF274_21170338_ChIP-Seq_K562_Hela1.15336370
84SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.15288379
85ZNF263_19887448_ChIP-Seq_K562_Human1.15271492
86RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.13828400
87NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.13552350
88SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.13029612
89BCOR_27268052_Chip-Seq_Bcells_Human1.12533948
90P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12121937
91TP63_22573176_ChIP-Seq_HFKS_Human1.10180111
92PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.09789352
93CTCF_27219007_Chip-Seq_Bcells_Human1.09176327
94SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08783920
95KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.08276052
96SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.08210293
97PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.07911488
98TET1_21490601_ChIP-Seq_MESCs_Mouse1.07538589
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.07041708
100THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.06513231
101NR3C1_23031785_ChIP-Seq_PC12_Mouse1.05246179
102PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03089488
103E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.02136409
104STAT6_21828071_ChIP-Seq_BEAS2B_Human1.01813349
105ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.01758417
106STAT3_23295773_ChIP-Seq_U87_Human1.01169350
107BCL6_27268052_Chip-Seq_Bcells_Human1.00798460
108KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.00773101
109GATA1_19941827_ChIP-Seq_MEL_Mouse1.00550117
110TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.00452854
111AR_25329375_ChIP-Seq_VCAP_Human0.99564742
112ESR1_15608294_ChIP-ChIP_MCF-7_Human0.98788821
113SMAD3_21741376_ChIP-Seq_EPCs_Human0.98554820
114SA1_27219007_Chip-Seq_Bcells_Human0.98048290
115* KDM2B_26808549_Chip-Seq_SUP-B15_Human0.97766480
116JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.97723726
117CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.97424339
118* SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.97361682
119TP53_22127205_ChIP-Seq_IMR90_Human0.97155907
120PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.96201101
121RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.95998736
122PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.95998688
123SMAD3_21741376_ChIP-Seq_HESCs_Human0.95524639
124YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93423739
125TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.93148112
126MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93119665
127LXR_22292898_ChIP-Seq_THP-1_Human0.92764278
128SMAD_19615063_ChIP-ChIP_OVARY_Human0.91462199
129TAF15_26573619_Chip-Seq_HEK293_Human0.89838896
130ZNF217_24962896_ChIP-Seq_MCF-7_Human0.89003713
131TCF4_23295773_ChIP-Seq_U87_Human0.88407667
132KLF4_19829295_ChIP-Seq_ESCs_Human0.87671454
133SMAD4_21741376_ChIP-Seq_HESCs_Human0.87223583
134SMAD3_21741376_ChIP-Seq_ESCs_Human0.86913275
135VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.86040804
136DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.85563875
137TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.85313277
138* SMC4_20622854_ChIP-Seq_HELA_Human0.84390398
139P300_19829295_ChIP-Seq_ESCs_Human0.83908737
140RXR_22108803_ChIP-Seq_LS180_Human0.83617274
141ARNT_22903824_ChIP-Seq_MCF-7_Human0.83368318
142AHR_22903824_ChIP-Seq_MCF-7_Human0.83108412
143SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83106116
144OCT4_19829295_ChIP-Seq_ESCs_Human0.81334134
145CBX2_27304074_Chip-Seq_ESCs_Mouse0.81168881
146TOP2B_26459242_ChIP-Seq_MCF-7_Human0.79137741
147TP53_20018659_ChIP-ChIP_R1E_Mouse0.78260803
148OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.77203838
149KDM2B_26808549_Chip-Seq_JURKAT_Human0.76272653
150OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.74790575
151TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.74539774
152TP53_16413492_ChIP-PET_HCT116_Human0.74436991

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.67086927
2MP0003880_abnormal_central_pattern4.71024808
3MP0003635_abnormal_synaptic_transmissio4.46221738
4MP0004270_analgesia3.86127138
5MP0002822_catalepsy3.64495913
6MP0009745_abnormal_behavioral_response3.59647067
7MP0002063_abnormal_learning/memory/cond3.56301755
8MP0002064_seizures3.37084143
9MP0003705_abnormal_hypodermis_morpholog3.36506337
10MP0009046_muscle_twitch3.21058953
11MP0005423_abnormal_somatic_nervous2.89663387
12MP0002572_abnormal_emotion/affect_behav2.89094932
13MP0001968_abnormal_touch/_nociception2.88470825
14MP0002272_abnormal_nervous_system2.67562322
15MP0001486_abnormal_startle_reflex2.65998140
16MP0002734_abnormal_mechanical_nocicepti2.59825965
17MP0005058_abnormal_lysosome_morphology2.45588328
18MP0001501_abnormal_sleep_pattern2.30797129
19MP0002736_abnormal_nociception_after2.10138084
20MP0001849_ear_inflammation2.09762137
21MP0008569_lethality_at_weaning2.09108594
22MP0001440_abnormal_grooming_behavior1.99824266
23MP0009780_abnormal_chondrocyte_physiolo1.98997004
24MP0002733_abnormal_thermal_nociception1.97453139
25MP0001970_abnormal_pain_threshold1.96758718
26MP0001348_abnormal_lacrimal_gland1.90747698
27MP0003329_amyloid_beta_deposits1.90723077
28MP0004811_abnormal_neuron_physiology1.89700369
29MP0008260_abnormal_autophagy1.86867386
30MP0002735_abnormal_chemical_nociception1.86082192
31MP0004858_abnormal_nervous_system1.84901709
32MP0002067_abnormal_sensory_capabilities1.81049285
33MP0002909_abnormal_adrenal_gland1.76021070
34MP0005409_darkened_coat_color1.70706924
35MP0002557_abnormal_social/conspecific_i1.67916588
36MP0005386_behavior/neurological_phenoty1.66328110
37MP0004924_abnormal_behavior1.66328110
38MP0003879_abnormal_hair_cell1.64684122
39MP0004885_abnormal_endolymph1.60372125
40MP0005646_abnormal_pituitary_gland1.60301134
41MP0002184_abnormal_innervation1.60084555
42MP0000955_abnormal_spinal_cord1.58013721
43MP0003123_paternal_imprinting1.56737016
44MP0000778_abnormal_nervous_system1.53753944
45MP0003633_abnormal_nervous_system1.52624714
46MP0002066_abnormal_motor_capabilities/c1.45679683
47MP0002882_abnormal_neuron_morphology1.39193899
48MP0002249_abnormal_larynx_morphology1.38985778
49MP0000579_abnormal_nail_morphology1.38360038
50MP0003075_altered_response_to1.34834861
51MP0005076_abnormal_cell_differentiation1.34411174
52MP0003787_abnormal_imprinting1.33225167
53MP0003183_abnormal_peptide_metabolism1.32864187
54MP0003283_abnormal_digestive_organ1.26856000
55MP0002089_abnormal_postnatal_growth/wei1.25359763
56MP0003631_nervous_system_phenotype1.25346416
57MP0001984_abnormal_olfaction1.24365036
58MP0005645_abnormal_hypothalamus_physiol1.23953702
59MP0001502_abnormal_circadian_rhythm1.20479589
60MP0008872_abnormal_physiological_respon1.18648999
61MP0000003_abnormal_adipose_tissue1.18541076
62MP0004142_abnormal_muscle_tone1.16288216
63MP0002152_abnormal_brain_morphology1.09913495
64MP0004185_abnormal_adipocyte_glucose1.08630113
65MP0001958_emphysema1.08129953
66MP0008874_decreased_physiological_sensi1.07592483
67MP0003453_abnormal_keratinocyte_physiol1.06164007
68MP0000751_myopathy1.03901896
69MP0001905_abnormal_dopamine_level1.02805671
70MP0001529_abnormal_vocalization1.01946671
71MP0005666_abnormal_adipose_tissue1.01598971
72MP0003690_abnormal_glial_cell1.00535293
73MP0001177_atelectasis0.97998812
74MP0002796_impaired_skin_barrier0.97668781
75MP0000678_abnormal_parathyroid_gland0.97460265
76MP0008961_abnormal_basal_metabolism0.97108040
77MP0002069_abnormal_eating/drinking_beha0.96575647
78MP0006276_abnormal_autonomic_nervous0.96566843
79MP0001346_abnormal_lacrimal_gland0.96306252
80MP0005167_abnormal_blood-brain_barrier0.96198290
81MP0004947_skin_inflammation0.93728117
82MP0009384_cardiac_valve_regurgitation0.93532424
83MP0003191_abnormal_cellular_cholesterol0.93409594
84MP0005375_adipose_tissue_phenotype0.91631012
85MP0002229_neurodegeneration0.89804326
86MP0003279_aneurysm0.88772471
87MP0004145_abnormal_muscle_electrophysio0.85831120
88MP0005535_abnormal_body_temperature0.85355903
89MP0003566_abnormal_cell_adhesion0.85183657
90MP0004233_abnormal_muscle_weight0.85007066
91MP0000604_amyloidosis0.84860263
92MP0003632_abnormal_nervous_system0.83871231
93MP0000920_abnormal_myelination0.83701088
94MP0000537_abnormal_urethra_morphology0.82514339
95MP0003634_abnormal_glial_cell0.81610357
96MP0000013_abnormal_adipose_tissue0.81584939
97MP0000569_abnormal_digit_pigmentation0.79848698
98MP0003172_abnormal_lysosome_physiology0.78916973
99MP0003122_maternal_imprinting0.78715119
100MP0003091_abnormal_cell_migration0.76483246
101MP0010234_abnormal_vibrissa_follicle0.76303482
102MP0004085_abnormal_heartbeat0.76295451
103MP0005451_abnormal_body_composition0.76195929
104MP0004381_abnormal_hair_follicle0.74119089
105MP0000566_synostosis0.72981393
106MP0005551_abnormal_eye_electrophysiolog0.72154879
107MP0003045_fibrosis0.71317413
108MP0000747_muscle_weakness0.70658373
109MP0003137_abnormal_impulse_conducting0.70314628
110MP0002090_abnormal_vision0.70117183
111MP0001299_abnormal_eye_distance/0.70002838
112MP0004510_myositis0.69151384
113MP0001963_abnormal_hearing_physiology0.68131847
114MP0005394_taste/olfaction_phenotype0.67965763
115MP0005499_abnormal_olfactory_system0.67965763
116MP0001485_abnormal_pinna_reflex0.67577961
117MP0009278_abnormal_bone_marrow0.67035312
118MP0001765_abnormal_ion_homeostasis0.66220829
119MP0003303_peritoneal_inflammation0.66117926
120MP0005166_decreased_susceptibility_to0.65369712
121MP0005623_abnormal_meninges_morphology0.64932208
122MP0003436_decreased_susceptibility_to0.64438741
123MP0004742_abnormal_vestibular_system0.61937068
124MP0002752_abnormal_somatic_nervous0.60663005
125MP0000462_abnormal_digestive_system0.60619559
126MP0010386_abnormal_urinary_bladder0.60167832
127MP0004215_abnormal_myocardial_fiber0.59511992
128MP0010769_abnormal_survival0.56661608
129MP0000631_abnormal_neuroendocrine_gland0.55678304
130MP0004043_abnormal_pH_regulation0.55459624
131MP0001188_hyperpigmentation0.55079918
132MP0001664_abnormal_digestion0.54298891
133MP0010768_mortality/aging0.53558380
134MP0001943_abnormal_respiration0.52651253
135MP0010770_preweaning_lethality0.51972921
136MP0002082_postnatal_lethality0.51972921
137MP0003956_abnormal_body_size0.51942358
138MP0003861_abnormal_nervous_system0.51723843
139MP0004484_altered_response_of0.50569693
140MP0004130_abnormal_muscle_cell0.49824761

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)8.23270811
2Focal motor seizures (HP:0011153)7.94723301
3Focal seizures (HP:0007359)6.01315359
4Visual hallucinations (HP:0002367)5.68253249
5Epileptic encephalopathy (HP:0200134)4.75197232
6Atonic seizures (HP:0010819)4.56089183
7Febrile seizures (HP:0002373)4.51075955
8Action tremor (HP:0002345)4.29175121
9Progressive cerebellar ataxia (HP:0002073)4.19061204
10Absence seizures (HP:0002121)4.13733137
11Generalized tonic-clonic seizures (HP:0002069)3.96105225
12Ankle clonus (HP:0011448)3.93694173
13Dialeptic seizures (HP:0011146)3.76467331
14Impaired vibration sensation in the lower limbs (HP:0002166)3.74487325
15Poor eye contact (HP:0000817)3.66677518
16Supranuclear gaze palsy (HP:0000605)3.61083808
17Annular pancreas (HP:0001734)3.52967008
18Broad face (HP:0000283)3.51954562
19Dysdiadochokinesis (HP:0002075)3.50561423
20Gaze-evoked nystagmus (HP:0000640)3.50161849
21J-shaped sella turcica (HP:0002680)3.46847258
22Abnormality of the lower motor neuron (HP:0002366)3.46099332
23Depression (HP:0000716)3.45744623
24Broad-based gait (HP:0002136)3.42978820
25Urinary bladder sphincter dysfunction (HP:0002839)3.42211232
26Abnormal social behavior (HP:0012433)3.35152412
27Impaired social interactions (HP:0000735)3.35152412
28Dysmetria (HP:0001310)3.35047676
29Postural instability (HP:0002172)3.32966526
30Papilledema (HP:0001085)3.27405923
31Cerebral aneurysm (HP:0004944)3.15422469
32Anxiety (HP:0000739)3.15221201
33Hyperacusis (HP:0010780)3.10325504
34Upper limb amyotrophy (HP:0009129)2.99344917
35Distal upper limb amyotrophy (HP:0007149)2.99344917
36Torticollis (HP:0000473)2.99156836
37Mutism (HP:0002300)2.97786451
38Intention tremor (HP:0002080)2.96110653
39Abnormal eating behavior (HP:0100738)2.94885807
40Hemiplegia (HP:0002301)2.94519611
41Cervical subluxation (HP:0003308)2.92601515
42Urinary urgency (HP:0000012)2.91293030
43Impaired smooth pursuit (HP:0007772)2.90732392
44Stridor (HP:0010307)2.89027236
45Ventricular fibrillation (HP:0001663)2.85765084
46Amblyopia (HP:0000646)2.84299193
47Focal dystonia (HP:0004373)2.83068747
48Truncal ataxia (HP:0002078)2.80951863
49Genetic anticipation (HP:0003743)2.78569335
50Spastic gait (HP:0002064)2.76537778
51Hemiparesis (HP:0001269)2.71974169
52Nuclear cataract (HP:0100018)2.71458313
53Dysostosis multiplex (HP:0000943)2.66640713
54Bradykinesia (HP:0002067)2.66277735
55Status epilepticus (HP:0002133)2.59955481
56Diplopia (HP:0000651)2.57999001
57Abnormality of binocular vision (HP:0011514)2.57999001
58Impaired vibratory sensation (HP:0002495)2.57712666
59Stereotypic behavior (HP:0000733)2.56911638
60Spinal canal stenosis (HP:0003416)2.56445225
61Scanning speech (HP:0002168)2.55395341
62Distal lower limb amyotrophy (HP:0008944)2.54208506
63Abnormality of ocular smooth pursuit (HP:0000617)2.53916591
64Megalencephaly (HP:0001355)2.49498375
65Craniofacial dystonia (HP:0012179)2.49254090
66Dysmetric saccades (HP:0000641)2.49219710
67Bundle branch block (HP:0011710)2.48750485
68Pointed chin (HP:0000307)2.45715942
69Thin bony cortex (HP:0002753)2.44947106
70Neurofibrillary tangles (HP:0002185)2.42664666
71Hyperventilation (HP:0002883)2.39675983
72Hand muscle atrophy (HP:0009130)2.37886580
73Cerebral inclusion bodies (HP:0100314)2.36332471
74Mucopolysacchariduria (HP:0008155)2.36306219
75Urinary glycosaminoglycan excretion (HP:0003541)2.36306219
76Bronchomalacia (HP:0002780)2.31988385
77Fetal akinesia sequence (HP:0001989)2.31282682
78Insomnia (HP:0100785)2.30548625
79Progressive inability to walk (HP:0002505)2.30548119
80Clonus (HP:0002169)2.29158443
81Lower limb muscle weakness (HP:0007340)2.26948752
82Abnormality of mucopolysaccharide metabolism (HP:0011020)2.26317497
83Abnormality of polysaccharide metabolism (HP:0011012)2.26317497
84Abnormality of glycosaminoglycan metabolism (HP:0004371)2.26317497
85Epileptiform EEG discharges (HP:0011182)2.22882168
86Sleep apnea (HP:0010535)2.22539454
87Turricephaly (HP:0000262)2.21209400
88Obstructive sleep apnea (HP:0002870)2.20870443
89EEG with generalized epileptiform discharges (HP:0011198)2.17856881
90Drooling (HP:0002307)2.15926533
91Excessive salivation (HP:0003781)2.15926533
92Generalized myoclonic seizures (HP:0002123)2.15218800
93Resting tremor (HP:0002322)2.12275700
94Hypsarrhythmia (HP:0002521)2.11830902
95Biconcave vertebral bodies (HP:0004586)2.09694881
96Abnormality of the periventricular white matter (HP:0002518)2.09643960
97Distal lower limb muscle weakness (HP:0009053)2.09530498
98Diminished motivation (HP:0000745)2.09217559
99Shallow orbits (HP:0000586)2.08512832
100Incomplete penetrance (HP:0003829)2.07822433
101Difficulty climbing stairs (HP:0003551)2.01051968
102Ankyloglossia (HP:0010296)2.00377012
103Neuronal loss in central nervous system (HP:0002529)1.98708105
104Delusions (HP:0000746)1.97938182
105Flat acetabular roof (HP:0003180)1.95677354
106Axonal loss (HP:0003447)1.95335310
107Abnormal EKG (HP:0003115)1.95107991
108Akinesia (HP:0002304)1.94430305
109Peripheral hypomyelination (HP:0007182)1.92737106
110Termporal pattern (HP:0011008)1.92288094
111Insidious onset (HP:0003587)1.92288094
112Lymphangioma (HP:0100764)1.91871404
113Tetraplegia (HP:0002445)1.91204569
114Lower limb amyotrophy (HP:0007210)1.91110243
115Gait ataxia (HP:0002066)1.91027619
116Rapidly progressive (HP:0003678)1.90796184
117Abnormality of saccadic eye movements (HP:0000570)1.90670905
118Ulnar bowing (HP:0003031)1.90317775
119Absent speech (HP:0001344)1.89639571
120Rigidity (HP:0002063)1.89258981
121Deformed sella turcica (HP:0002681)1.87903007
122Lower limb asymmetry (HP:0100559)1.87662725
123Mitral regurgitation (HP:0001653)1.86447866
124Abnormality of the corticospinal tract (HP:0002492)1.84460337
125Metaphyseal cupping (HP:0003021)1.83729901
126Distal sensory impairment (HP:0002936)1.83473149
127Pheochromocytoma (HP:0002666)1.82167346
128Hyperparathyroidism (HP:0000843)1.79651544
129Limb dystonia (HP:0002451)1.75876542
130Spinal cord compression (HP:0002176)1.74938706
131Psychosis (HP:0000709)1.74103526
132Abnormal atrioventricular conduction (HP:0005150)1.73083765
133Inability to walk (HP:0002540)1.71286491
134Amyotrophic lateral sclerosis (HP:0007354)1.70658564
135Hypercortisolism (HP:0001578)1.70086655
136Slow saccadic eye movements (HP:0000514)1.70020686
137Onion bulb formation (HP:0003383)1.69266512
138Apathy (HP:0000741)1.68896064
139Spastic tetraparesis (HP:0001285)1.68793233
140Foot dorsiflexor weakness (HP:0009027)1.68008388
141Achilles tendon contracture (HP:0001771)1.67627586
142Joint stiffness (HP:0001387)1.67533633
143Agitation (HP:0000713)1.67239056
144Interstitial pulmonary disease (HP:0006530)1.66839711
145Aplasia involving bones of the upper limbs (HP:0009823)1.64870692
146Aplasia of the phalanges of the hand (HP:0009802)1.64870692
147Aplasia involving bones of the extremities (HP:0009825)1.64870692
148Dementia (HP:0000726)1.63910872
149Protrusio acetabuli (HP:0003179)1.63455925
150Hammertoe (HP:0001765)1.60660888

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.10357158
2TRIB34.31663184
3NTRK34.28697823
4MAP3K94.23455891
5DAPK23.10419395
6PRKD32.78315320
7MAP3K42.63703430
8MINK12.55365887
9SIK12.49031451
10PAK62.47008943
11KSR22.39994870
12MARK12.31355496
13CAMKK12.12666928
14DAPK12.01578454
15MAP2K71.98961881
16NTRK21.96025844
17NTRK11.84780116
18RIPK41.78289092
19TYRO31.75206242
20STK381.67980476
21MAP2K61.65675487
22MAP2K41.64180912
23CDK51.59280700
24PKN21.56347153
25PRPF4B1.53204390
26MAP2K31.52612394
27MAPK151.50902126
28KSR11.48356635
29ARAF1.45059901
30MAP3K131.41416162
31EPHA21.41275324
32PINK11.41018886
33TAOK11.36465097
34UHMK11.33856119
35TESK11.33816503
36ERN11.33449895
37MAP3K121.31476662
38GRK51.30268551
39SIK21.30158156
40SMG11.29978386
41CDK191.29218772
42TNIK1.24934710
43FES1.23704137
44MAP3K21.18963514
45MAPK121.18518541
46EEF2K1.15189790
47PRKCG1.14170235
48PLK21.10737072
49RAF11.03994359
50ALK1.03511852
51FGFR41.03326236
52PTK21.01915931
53CAMK11.01841663
54LATS21.00344743
55PRKCH0.98550380
56STK110.95731912
57CDK150.92914332
58MAP3K110.92401275
59CDK180.91658514
60PNCK0.91042771
61MAPK130.89861735
62PHKG10.89051526
63PHKG20.89051526
64MST1R0.88589815
65CAMKK20.86068750
66DDR20.84332289
67CDK140.84152568
68CAMK2A0.83510047
69RPS6KA20.83069106
70CDK11A0.81756742
71RIPK10.78072339
72SGK2230.77274697
73SGK4940.77274697
74ICK0.76008590
75SIK30.75453708
76PDK10.74787227
77TNK20.73973842
78RET0.73572786
79PTK2B0.73204259
80NEK10.72603009
81MET0.72096761
82LMTK20.70867305
83CAMK2B0.69930563
84CDC42BPA0.69658548
85SGK10.69365751
86MARK20.69178292
87PDPK10.69160368
88MAP3K60.68883297
89PTK60.66768533
90IRAK30.66003243
91SGK30.65283394
92BRSK10.64745842
93PAK30.63290920
94MAP3K10.61861693
95FGR0.59832503
96ERBB20.59420000
97MTOR0.58492542
98OXSR10.57665519
99SGK20.57340134
100MAP3K70.56828558
101DAPK30.56749776
102CASK0.55180635
103BMPR20.54985926
104DYRK1A0.54402422
105RPS6KA30.53844995
106PRKD20.52832286
107IRAK20.52726620
108TTN0.52384992
109NEK60.51793272
110PRKG20.51440497
111CAMK40.51047507
112PRKCZ0.50954108
113ZAP700.49829756
114FGFR20.49774442
115MAPK100.48297745
116CDK120.45947526
117MAPK80.45599153
118BMX0.45539340
119CAMK2G0.44069285
120DMPK0.43150906
121PDGFRB0.42786434
122GRK60.41691688
123FYN0.41188031
124CSNK1G20.41019895
125EPHB10.40557929
126NME20.39585441
127PDGFRA0.39299586
128BRAF0.39219739
129TAOK20.38938697
130CAMK1G0.38757439
131MAPKAPK30.38552282
132CAMK2D0.37196637
133MAP2K10.35375327
134SCYL20.34932424
135WNK10.31177960
136PRKCB0.27461018
137PRKCE0.26869150

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.47908260
2Synaptic vesicle cycle_Homo sapiens_hsa047213.36825313
3Olfactory transduction_Homo sapiens_hsa047403.01240531
4GABAergic synapse_Homo sapiens_hsa047272.70670149
5Circadian entrainment_Homo sapiens_hsa047132.70516141
6Long-term potentiation_Homo sapiens_hsa047202.69963394
7Glutamatergic synapse_Homo sapiens_hsa047242.61305250
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.53753390
9Amphetamine addiction_Homo sapiens_hsa050312.50644027
10Morphine addiction_Homo sapiens_hsa050322.48805405
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.28258610
12Salivary secretion_Homo sapiens_hsa049702.19629796
13Dopaminergic synapse_Homo sapiens_hsa047282.12235526
14Insulin secretion_Homo sapiens_hsa049112.07679100
15Nitrogen metabolism_Homo sapiens_hsa009102.04058300
16Gastric acid secretion_Homo sapiens_hsa049712.00969569
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.93786249
18Cholinergic synapse_Homo sapiens_hsa047251.93009512
19Other glycan degradation_Homo sapiens_hsa005111.91667490
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.75517526
21Oxytocin signaling pathway_Homo sapiens_hsa049211.70128739
22Long-term depression_Homo sapiens_hsa047301.61044172
23Cocaine addiction_Homo sapiens_hsa050301.58770653
24Calcium signaling pathway_Homo sapiens_hsa040201.58078612
25Renin secretion_Homo sapiens_hsa049241.55573242
26GnRH signaling pathway_Homo sapiens_hsa049121.54375930
27Taste transduction_Homo sapiens_hsa047421.52004269
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.44083809
29Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.43427733
30Serotonergic synapse_Homo sapiens_hsa047261.39838691
31Gap junction_Homo sapiens_hsa045401.36155892
32Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.35785827
33Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.34308927
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.34267670
35Vitamin B6 metabolism_Homo sapiens_hsa007501.31689034
36cAMP signaling pathway_Homo sapiens_hsa040241.28491762
37Type II diabetes mellitus_Homo sapiens_hsa049301.22968352
38Glioma_Homo sapiens_hsa052141.21113973
39Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17141320
40Estrogen signaling pathway_Homo sapiens_hsa049151.17044498
41Collecting duct acid secretion_Homo sapiens_hsa049661.11867357
42Notch signaling pathway_Homo sapiens_hsa043301.09106611
43ErbB signaling pathway_Homo sapiens_hsa040121.08207720
44Melanogenesis_Homo sapiens_hsa049161.03820543
45Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.02321189
46cGMP-PKG signaling pathway_Homo sapiens_hsa040220.98891200
47Oocyte meiosis_Homo sapiens_hsa041140.98280183
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.97000535
49Cyanoamino acid metabolism_Homo sapiens_hsa004600.94825564
50Dorso-ventral axis formation_Homo sapiens_hsa043200.92433865
51Phospholipase D signaling pathway_Homo sapiens_hsa040720.91015248
52Axon guidance_Homo sapiens_hsa043600.90580840
53Vascular smooth muscle contraction_Homo sapiens_hsa042700.88321104
54Cardiac muscle contraction_Homo sapiens_hsa042600.88097645
55Pancreatic secretion_Homo sapiens_hsa049720.86644989
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.86226197
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.81378159
58AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81231929
59Chronic myeloid leukemia_Homo sapiens_hsa052200.81180672
60Thyroid hormone synthesis_Homo sapiens_hsa049180.80328455
61Prolactin signaling pathway_Homo sapiens_hsa049170.78346538
62Choline metabolism in cancer_Homo sapiens_hsa052310.78285797
63Acute myeloid leukemia_Homo sapiens_hsa052210.76247286
64Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.75410551
65VEGF signaling pathway_Homo sapiens_hsa043700.75089095
66Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.73207630
67mTOR signaling pathway_Homo sapiens_hsa041500.71607656
68AMPK signaling pathway_Homo sapiens_hsa041520.71408584
69Central carbon metabolism in cancer_Homo sapiens_hsa052300.71353570
70MAPK signaling pathway_Homo sapiens_hsa040100.71285732
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.71153763
72Dilated cardiomyopathy_Homo sapiens_hsa054140.69436778
73Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.68477854
74Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67597201
75Neurotrophin signaling pathway_Homo sapiens_hsa047220.65657041
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64475493
77Vibrio cholerae infection_Homo sapiens_hsa051100.64014887
78B cell receptor signaling pathway_Homo sapiens_hsa046620.63207625
79Bile secretion_Homo sapiens_hsa049760.63130975
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62090280
81Thyroid hormone signaling pathway_Homo sapiens_hsa049190.61233420
82Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.61026903
83Glucagon signaling pathway_Homo sapiens_hsa049220.59338115
84Lysosome_Homo sapiens_hsa041420.59041724
85Rap1 signaling pathway_Homo sapiens_hsa040150.59016618
86Endocytosis_Homo sapiens_hsa041440.58362346
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57277586
88Focal adhesion_Homo sapiens_hsa045100.57147752
89Leukocyte transendothelial migration_Homo sapiens_hsa046700.57001610
90Adipocytokine signaling pathway_Homo sapiens_hsa049200.56813576
91Circadian rhythm_Homo sapiens_hsa047100.56461373
92HIF-1 signaling pathway_Homo sapiens_hsa040660.55769182
93Fatty acid biosynthesis_Homo sapiens_hsa000610.55500483
94Fructose and mannose metabolism_Homo sapiens_hsa000510.54414648
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.53954493
96Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.53757312
97Phototransduction_Homo sapiens_hsa047440.53580702
98Ras signaling pathway_Homo sapiens_hsa040140.53328577
99Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53265701
100ABC transporters_Homo sapiens_hsa020100.52797094
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52558551
102Amoebiasis_Homo sapiens_hsa051460.52543957
103Type I diabetes mellitus_Homo sapiens_hsa049400.51149330
104Non-small cell lung cancer_Homo sapiens_hsa052230.49421855
105Inositol phosphate metabolism_Homo sapiens_hsa005620.48031595
106Hepatitis C_Homo sapiens_hsa051600.47064747
107Bladder cancer_Homo sapiens_hsa052190.46519038
108Arginine biosynthesis_Homo sapiens_hsa002200.45422750
109Endometrial cancer_Homo sapiens_hsa052130.43844718
110Prion diseases_Homo sapiens_hsa050200.43791061
111Wnt signaling pathway_Homo sapiens_hsa043100.43245449
112Alcoholism_Homo sapiens_hsa050340.43106721
113Insulin signaling pathway_Homo sapiens_hsa049100.42774202
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41900263
115Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39271165
116Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38182554
117Chemokine signaling pathway_Homo sapiens_hsa040620.35891617
118Renal cell carcinoma_Homo sapiens_hsa052110.32885639
119African trypanosomiasis_Homo sapiens_hsa051430.30686999
120Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.30082808
121Glycerophospholipid metabolism_Homo sapiens_hsa005640.29207901
122Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.29155288
123Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.28263509
124Ovarian steroidogenesis_Homo sapiens_hsa049130.26685037
125Tight junction_Homo sapiens_hsa045300.25068316

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