KLC4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine metabolic process (GO:0006558)6.26651976
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)6.26651976
3L-phenylalanine catabolic process (GO:0006559)6.22162526
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)6.22162526
5epoxygenase P450 pathway (GO:0019373)6.21981271
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.99324502
7aromatic amino acid family catabolic process (GO:0009074)5.72636674
8glyoxylate metabolic process (GO:0046487)5.47515014
9indole-containing compound catabolic process (GO:0042436)5.37167488
10indolalkylamine catabolic process (GO:0046218)5.37167488
11tryptophan catabolic process (GO:0006569)5.37167488
12kynurenine metabolic process (GO:0070189)5.33927373
13sulfur amino acid catabolic process (GO:0000098)5.29692241
14urea cycle (GO:0000050)5.10817336
15urea metabolic process (GO:0019627)5.10817336
16fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.08799601
17tryptophan metabolic process (GO:0006568)5.01736935
18lysine metabolic process (GO:0006553)5.00284119
19lysine catabolic process (GO:0006554)5.00284119
20high-density lipoprotein particle remodeling (GO:0034375)4.95906035
21cysteine metabolic process (GO:0006534)4.95587485
22alpha-linolenic acid metabolic process (GO:0036109)4.94928602
23bile acid biosynthetic process (GO:0006699)4.84340156
24regulation of cholesterol esterification (GO:0010872)4.81844103
25regulation of triglyceride catabolic process (GO:0010896)4.79996842
26negative regulation of cholesterol transport (GO:0032375)4.74427544
27negative regulation of sterol transport (GO:0032372)4.74427544
28phospholipid efflux (GO:0033700)4.70712512
29nitrogen cycle metabolic process (GO:0071941)4.69618150
30homocysteine metabolic process (GO:0050667)4.64497346
31serine family amino acid catabolic process (GO:0009071)4.64312892
32drug catabolic process (GO:0042737)4.64127617
33amino-acid betaine metabolic process (GO:0006577)4.50874781
34negative regulation of fibrinolysis (GO:0051918)4.40846889
35reverse cholesterol transport (GO:0043691)4.40649491
36bile acid metabolic process (GO:0008206)4.37998072
37cellular ketone body metabolic process (GO:0046950)4.37226064
38flavonoid metabolic process (GO:0009812)4.34637821
39protein-lipid complex remodeling (GO:0034368)4.32798314
40macromolecular complex remodeling (GO:0034367)4.32798314
41plasma lipoprotein particle remodeling (GO:0034369)4.32798314
42peptidyl-glutamic acid carboxylation (GO:0017187)4.28785080
43protein carboxylation (GO:0018214)4.28785080
44bile acid and bile salt transport (GO:0015721)4.27554840
45aromatic amino acid family metabolic process (GO:0009072)4.26110025
46intestinal cholesterol absorption (GO:0030299)4.23823299
47regulation of protein activation cascade (GO:2000257)4.20957492
48regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.20187592
49complement activation, alternative pathway (GO:0006957)4.16429163
50acylglycerol homeostasis (GO:0055090)4.14188397
51triglyceride homeostasis (GO:0070328)4.14188397
52drug transmembrane transport (GO:0006855)4.09995671
53regulation of fibrinolysis (GO:0051917)4.06583029
54alpha-amino acid catabolic process (GO:1901606)4.06400780
55cholesterol efflux (GO:0033344)4.04970573
56positive regulation of triglyceride lipase activity (GO:0061365)4.03270379
57positive regulation of lipoprotein lipase activity (GO:0051006)4.03270379
58plasma lipoprotein particle assembly (GO:0034377)4.03112027
59regulation of cholesterol homeostasis (GO:2000188)4.02232740
60plasma lipoprotein particle clearance (GO:0034381)4.01460742
61ethanol metabolic process (GO:0006067)3.98816396
62fat-soluble vitamin biosynthetic process (GO:0042362)3.95639178
63regulation of complement activation (GO:0030449)3.95016602
64NADH metabolic process (GO:0006734)3.89188560
65cellular glucuronidation (GO:0052695)3.89152415
66omega-hydroxylase P450 pathway (GO:0097267)3.89124777
67regulation of bile acid biosynthetic process (GO:0070857)3.87607899
68cellular amino acid catabolic process (GO:0009063)3.86164128
69cellular modified amino acid catabolic process (GO:0042219)3.84998397
70ethanol oxidation (GO:0006069)3.84547249
71intestinal absorption (GO:0050892)3.83528951
72short-chain fatty acid metabolic process (GO:0046459)3.82287470
73benzene-containing compound metabolic process (GO:0042537)3.81882874
74exogenous drug catabolic process (GO:0042738)3.81183945
75urate metabolic process (GO:0046415)3.80646708
76serine family amino acid metabolic process (GO:0009069)3.79174655
77cholesterol homeostasis (GO:0042632)3.77312527
78ketone body metabolic process (GO:1902224)3.77121300
79fatty acid beta-oxidation (GO:0006635)3.73229480
802-oxoglutarate metabolic process (GO:0006103)3.72770324
81sterol homeostasis (GO:0055092)3.72209276
82glycine metabolic process (GO:0006544)3.71770477
83indolalkylamine metabolic process (GO:0006586)3.71555050
84phospholipid homeostasis (GO:0055091)3.71282841
85protein-lipid complex assembly (GO:0065005)3.70066717
86lipoprotein metabolic process (GO:0042157)3.69172473
87arginine metabolic process (GO:0006525)3.67595040
88fatty acid oxidation (GO:0019395)3.66350484
89tyrosine metabolic process (GO:0006570)3.65998666
90drug transport (GO:0015893)3.65164095
91glutamate metabolic process (GO:0006536)3.64818218
92positive regulation of lipid catabolic process (GO:0050996)3.64281876
93drug metabolic process (GO:0017144)3.63731458
94cellular biogenic amine catabolic process (GO:0042402)3.63321527
95amine catabolic process (GO:0009310)3.63321527
96phenylpropanoid metabolic process (GO:0009698)3.62308473
97very-low-density lipoprotein particle assembly (GO:0034379)3.59416461
98lipid oxidation (GO:0034440)3.58744748
99oxidative demethylation (GO:0070989)3.57069167
100plasma lipoprotein particle organization (GO:0071827)3.57016025
101aspartate family amino acid catabolic process (GO:0009068)3.56045126
102heme transport (GO:0015886)3.54976694
103organic acid catabolic process (GO:0016054)3.54186784
104carboxylic acid catabolic process (GO:0046395)3.54186784
105angiotensin maturation (GO:0002003)3.53398196
106carnitine metabolic process (GO:0009437)3.53291839
107fatty acid catabolic process (GO:0009062)3.50944933
108diacylglycerol metabolic process (GO:0046339)3.50489857
109lipoprotein transport (GO:0042953)3.49080742
110glucuronate metabolic process (GO:0019585)3.48425758
111uronic acid metabolic process (GO:0006063)3.48425758
112monocarboxylic acid catabolic process (GO:0072329)3.47378811
113proline metabolic process (GO:0006560)3.47199752
114low-density lipoprotein particle remodeling (GO:0034374)3.40553215
115alkaloid metabolic process (GO:0009820)3.38401946
116protein-lipid complex subunit organization (GO:0071825)3.34451124
117nucleobase catabolic process (GO:0046113)3.27337078
118regulation of cholesterol metabolic process (GO:0090181)3.22294419
119hormone catabolic process (GO:0042447)3.18883634
120fructose metabolic process (GO:0006000)3.18037642
121negative regulation of lipase activity (GO:0060192)3.16257725
122pyrimidine nucleobase catabolic process (GO:0006208)3.14343651
123glutamine family amino acid biosynthetic process (GO:0009084)3.09339271
124blood coagulation, intrinsic pathway (GO:0007597)3.06017152
125neurotransmitter catabolic process (GO:0042135)2.99539377
126regulation of guanylate cyclase activity (GO:0031282)2.94594970
127arginine catabolic process (GO:0006527)2.94149853
128complement activation, classical pathway (GO:0006958)2.91015941
129positive regulation of fatty acid biosynthetic process (GO:0045723)2.89236018
130protein activation cascade (GO:0072376)2.89036158
131renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)2.83974933
132oxaloacetate metabolic process (GO:0006107)2.81416394
133sodium ion homeostasis (GO:0055078)2.77581080
134complement activation (GO:0006956)2.66389423

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse9.73148695
2RXR_22158963_ChIP-Seq_LIVER_Mouse6.97567768
3PPARA_22158963_ChIP-Seq_LIVER_Mouse6.33287106
4LXR_22158963_ChIP-Seq_LIVER_Mouse5.33326475
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.12553710
6EGR1_23403033_ChIP-Seq_LIVER_Mouse5.09505033
7FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.23829898
8CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.16578222
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.14322609
10NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.08476523
11CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.42496047
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.38479672
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.32504184
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.27886342
15DROSHA_22980978_ChIP-Seq_HELA_Human1.95823327
16CLOCK_20551151_ChIP-Seq_293T_Human1.90058714
17CTCF_27219007_Chip-Seq_Bcells_Human1.83165942
18DNAJC2_21179169_ChIP-ChIP_NT2_Human1.77426433
19THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.76718586
20TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.75446140
21EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.71146418
22RARG_19884340_ChIP-ChIP_MEFs_Mouse1.66113691
23SOX2_27498859_Chip-Seq_STOMACH_Mouse1.65788006
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.55273792
25NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.52247931
26SMC4_20622854_ChIP-Seq_HELA_Human1.45679873
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.44810869
28CDX2_20551321_ChIP-Seq_CACO-2_Human1.44611866
29LXR_22292898_ChIP-Seq_THP-1_Human1.41383897
30ELF1_20517297_ChIP-Seq_JURKAT_Human1.41040579
31NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.38239770
32STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.38185032
33ERG_21242973_ChIP-ChIP_JURKAT_Human1.37563129
34EZH2_22144423_ChIP-Seq_EOC_Human1.36621559
35HNF4A_19822575_ChIP-Seq_HepG2_Human1.34972590
36ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.34365481
37FOXA2_19822575_ChIP-Seq_HepG2_Human1.34065789
38GATA4_25053715_ChIP-Seq_YYC3_Human1.33632480
39SUZ12_27294783_Chip-Seq_ESCs_Mouse1.32866148
40TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.32764134
41EZH2_27294783_Chip-Seq_ESCs_Mouse1.32701757
42ZNF263_19887448_ChIP-Seq_K562_Human1.30672562
43ESR2_21235772_ChIP-Seq_MCF-7_Human1.28583307
44CTCF_20526341_ChIP-Seq_ESCs_Human1.26607248
45YY1_22570637_ChIP-Seq_MALME-3M_Human1.26250707
46ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.24513027
47IRF8_22096565_ChIP-ChIP_GC-B_Human1.22735160
48GATA1_22025678_ChIP-Seq_K562_Human1.18451376
49STAT3_1855785_ChIP-Seq_MESCs_Mouse1.17483287
50ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.17383621
51* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.17257078
52REST_18959480_ChIP-ChIP_MESCs_Mouse1.16513290
53ERA_21632823_ChIP-Seq_H3396_Human1.12462857
54RXRA_24833708_ChIP-Seq_LIVER_Mouse1.12415707
55GATA6_25053715_ChIP-Seq_YYC3_Human1.10284277
56ZFP281_18757296_ChIP-ChIP_E14_Mouse1.09783292
57OCT4_20526341_ChIP-Seq_ESCs_Human1.09312634
58RACK7_27058665_Chip-Seq_MCF-7_Human1.08668464
59EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.07982909
60STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.07241613
61REST_21632747_ChIP-Seq_MESCs_Mouse1.06950040
62ESR1_21235772_ChIP-Seq_MCF-7_Human1.06848006
63SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.06402027
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.04784158
65SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.04669138
66SOX2_21211035_ChIP-Seq_LN229_Human1.03327273
67SA1_27219007_Chip-Seq_ERYTHROID_Human1.02595815
68RAC3_21632823_ChIP-Seq_H3396_Human1.01389743
69OCT4_19829295_ChIP-Seq_ESCs_Human1.01013370
70MYC_19829295_ChIP-Seq_ESCs_Human0.97681222
71PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.97011591
72* TP63_22573176_ChIP-Seq_HFKS_Human0.96994885
73SRY_22984422_ChIP-ChIP_TESTIS_Rat0.94645848
74ETS1_21867929_ChIP-Seq_TH2_Mouse0.94619026
75RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.93911477
76* JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.93004097
77RARA_24833708_ChIP-Seq_LIVER_Mouse0.92287992
78CTCF_27219007_Chip-Seq_ERYTHROID_Human0.91412264
79IKZF1_21737484_ChIP-ChIP_HCT116_Human0.91281016
80JARID2_20075857_ChIP-Seq_MESCs_Mouse0.91211384
81TP63_17297297_ChIP-ChIP_HaCaT_Human0.91034189
82TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.90739434
83BCL6_27268052_Chip-Seq_Bcells_Human0.90184673
84ESR1_15608294_ChIP-ChIP_MCF-7_Human0.89321452
85TET1_21451524_ChIP-Seq_MESCs_Mouse0.89155242
86BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.88818872
87ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88795552
88NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse0.88181181
89ATF3_27146783_Chip-Seq_COLON_Human0.87254995
90FOXH1_21741376_ChIP-Seq_ESCs_Human0.86928399
91P53_21459846_ChIP-Seq_SAOS-2_Human0.86336282
92MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.86144338
93BCOR_27268052_Chip-Seq_Bcells_Human0.86029455
94SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.85572113
95NANOG_20526341_ChIP-Seq_ESCs_Human0.85417114
96IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.85347965
97EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.84724350
98P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.84480060
99KDM2B_26808549_Chip-Seq_K562_Human0.83994664
100SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.83493954
101OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.83182820
102MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.82894682
103P68_20966046_ChIP-Seq_HELA_Human0.82624605
104RARB_24833708_ChIP-Seq_LIVER_Mouse0.81641455
105RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.80802896
106RAD21_21589869_ChIP-Seq_MESCs_Mouse0.80452394
107POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.79155832
108Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.78448099
109GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.78173096
110KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.78041693
111GATA1_19941827_ChIP-Seq_MEL_Mouse0.77690013
112E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.77292117
113ELK3_25401928_ChIP-Seq_HUVEC_Human0.77255552
114CREB1_26743006_Chip-Seq_LNCaP_Human0.76397769
115GATA1_19941826_ChIP-Seq_K562_Human0.76324440
116TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.75474323
117PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.75441251
118HTT_18923047_ChIP-ChIP_STHdh_Human0.74881554
119SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.74697196
120GATA1_22383799_ChIP-Seq_G1ME_Mouse0.74576010
121BRD4_27068464_Chip-Seq_AML-cells_Mouse0.72000920
122PHF8_20622854_ChIP-Seq_HELA_Human0.71940144
123SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.71737558
124SOX2_20726797_ChIP-Seq_SW620_Human0.71581341
125ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.71496626
126OCT4_18692474_ChIP-Seq_MEFs_Mouse0.70852687
127PPAR_26484153_Chip-Seq_NCI-H1993_Human0.70790728
128PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.70664771
129GATA2_19941826_ChIP-Seq_K562_Human0.70186325
130TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.68590413
131CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.68497910
132KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.67730217
133CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.67275984
134SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.66684260
135E2F1_20622854_ChIP-Seq_HELA_Human0.66025823
136CTCF_21964334_ChIP-Seq_BJAB-B_Human0.65347056
137CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.64218678
138CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.63775087
139FOXO3_23340844_ChIP-Seq_DLD1_Human0.62630550
140SA1_27219007_Chip-Seq_Bcells_Human0.62401745
141SALL4_18804426_ChIP-ChIP_XEN_Mouse0.62358947
142EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.61155073
143CTCF_26484167_Chip-Seq_Bcells_Mouse0.60812068
144TAF2_19829295_ChIP-Seq_ESCs_Human0.60793621
145P300_27268052_Chip-Seq_Bcells_Human0.60700098
146NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.60065931
147AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.59269805
148VDR_21846776_ChIP-Seq_THP-1_Human0.58709174

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis7.67315064
2MP0002139_abnormal_hepatobiliary_system7.41124665
3MP0005085_abnormal_gallbladder_physiolo5.59681549
4MP0005365_abnormal_bile_salt5.38741066
5MP0008875_abnormal_xenobiotic_pharmacok4.68212382
6MP0009840_abnormal_foam_cell3.90562419
7MP0003806_abnormal_nucleotide_metabolis3.62183746
8MP0003252_abnormal_bile_duct3.61561866
9MP0010329_abnormal_lipoprotein_level3.33417120
10MP0001666_abnormal_nutrient_absorption3.17524921
11MP0005332_abnormal_amino_acid2.84539191
12MP0003191_abnormal_cellular_cholesterol2.77747450
13MP0004019_abnormal_vitamin_homeostasis2.63792115
14MP0005083_abnormal_biliary_tract2.50859936
15MP0003122_maternal_imprinting2.16620071
16MP0003195_calcinosis2.14732412
17MP0003879_abnormal_hair_cell2.13667072
18MP0000609_abnormal_liver_physiology2.07020782
19MP0004147_increased_porphyrin_level2.05426568
20MP0002118_abnormal_lipid_homeostasis1.95685550
21MP0005319_abnormal_enzyme/_coenzyme1.91354902
22MP0005423_abnormal_somatic_nervous1.89325500
23MP0003329_amyloid_beta_deposits1.86722484
24MP0002138_abnormal_hepatobiliary_system1.84500709
25MP0009643_abnormal_urine_homeostasis1.80660138
26MP0004270_analgesia1.69911808
27MP0001764_abnormal_homeostasis1.62865801
28MP0001986_abnormal_taste_sensitivity1.50993998
29MP0005584_abnormal_enzyme/coenzyme_acti1.47623801
30MP0003705_abnormal_hypodermis_morpholog1.39827524
31MP0000566_synostosis1.38265617
32MP0003868_abnormal_feces_composition1.36203940
33MP0005058_abnormal_lysosome_morphology1.36040218
34MP0005636_abnormal_mineral_homeostasis1.25432274
35MP0001664_abnormal_digestion1.24492751
36MP0003011_delayed_dark_adaptation1.23384794
37MP0005451_abnormal_body_composition1.22266339
38MP0006276_abnormal_autonomic_nervous1.17211494
39MP0001502_abnormal_circadian_rhythm1.16535837
40MP0004859_abnormal_synaptic_plasticity1.13120106
41MP0003656_abnormal_erythrocyte_physiolo1.12762027
42MP0002132_abnormal_respiratory_system1.12413662
43MP0000598_abnormal_liver_morphology1.12325978
44MP0003186_abnormal_redox_activity1.09478059
45MP0005084_abnormal_gallbladder_morpholo1.08506016
46MP0001756_abnormal_urination1.07785119
47MP0005670_abnormal_white_adipose1.07219032
48MP0004264_abnormal_extraembryonic_tissu1.06228435
49MP0008872_abnormal_physiological_respon1.06187193
50MP0006036_abnormal_mitochondrial_physio1.06024318
51MP0001501_abnormal_sleep_pattern1.04944592
52MP0003123_paternal_imprinting1.02622202
53MP0003880_abnormal_central_pattern1.00080888
54MP0010234_abnormal_vibrissa_follicle0.99599308
55MP0005645_abnormal_hypothalamus_physiol0.98383922
56MP0008469_abnormal_protein_level0.95845389
57MP0009642_abnormal_blood_homeostasis0.94387680
58MP0005167_abnormal_blood-brain_barrier0.93771889
59MP0004043_abnormal_pH_regulation0.93511856
60MP0002136_abnormal_kidney_physiology0.91621126
61MP0009764_decreased_sensitivity_to0.91257923
62MP0009697_abnormal_copulation0.90524315
63MP0002653_abnormal_ependyma_morphology0.90201731
64MP0002822_catalepsy0.89827395
65MP0000604_amyloidosis0.87655442
66MP0000678_abnormal_parathyroid_gland0.82976819
67MP0001529_abnormal_vocalization0.81697224
68MP0002557_abnormal_social/conspecific_i0.81694912
69MP0002249_abnormal_larynx_morphology0.81085420
70MP0004130_abnormal_muscle_cell0.77121657
71MP0002064_seizures0.76716907
72MP0009763_increased_sensitivity_to0.76554924
73MP0002078_abnormal_glucose_homeostasis0.76481230
74MP0003787_abnormal_imprinting0.74911689
75MP0004858_abnormal_nervous_system0.74683767
76MP0005376_homeostasis/metabolism_phenot0.74257871
77MP0002909_abnormal_adrenal_gland0.73404760
78MP0000013_abnormal_adipose_tissue0.72882666
79MP0001984_abnormal_olfaction0.72809604
80MP0001765_abnormal_ion_homeostasis0.72552146
81MP0003635_abnormal_synaptic_transmissio0.72316729
82MP0003300_gastrointestinal_ulcer0.70538416
83MP0000538_abnormal_urinary_bladder0.70051238
84MP0005266_abnormal_metabolism0.69802468
85MP0005464_abnormal_platelet_physiology0.68144901
86MP0002734_abnormal_mechanical_nocicepti0.67946769
87MP0002089_abnormal_postnatal_growth/wei0.67745794
88MP0006035_abnormal_mitochondrial_morpho0.67604433
89MP0003878_abnormal_ear_physiology0.67388562
90MP0005377_hearing/vestibular/ear_phenot0.67388562
91MP0002837_dystrophic_cardiac_calcinosis0.67369787
92MP0002971_abnormal_brown_adipose0.67133675
93MP0002638_abnormal_pupillary_reflex0.67131563
94MP0005551_abnormal_eye_electrophysiolog0.66810301
95MP0002063_abnormal_learning/memory/cond0.66591170
96MP0005666_abnormal_adipose_tissue0.66161923
97MP0002272_abnormal_nervous_system0.65345210
98MP0009745_abnormal_behavioral_response0.64422521
99MP0002069_abnormal_eating/drinking_beha0.64357776
100MP0010368_abnormal_lymphatic_system0.64354652
101MP0005220_abnormal_exocrine_pancreas0.64335073
102MP0003436_decreased_susceptibility_to0.62782364
103MP0005448_abnormal_energy_balance0.62683572
104MP0001663_abnormal_digestive_system0.62464097
105MP0002572_abnormal_emotion/affect_behav0.62236889
106MP0002254_reproductive_system_inflammat0.61665260
107MP0005334_abnormal_fat_pad0.61264757
108MP0003121_genomic_imprinting0.60756961
109MP0003690_abnormal_glial_cell0.60599708
110MP0001873_stomach_inflammation0.60598207
111MP0005499_abnormal_olfactory_system0.59498464
112MP0005394_taste/olfaction_phenotype0.59498464
113MP0005386_behavior/neurological_phenoty0.59156693
114MP0004924_abnormal_behavior0.59156693
115MP0005166_decreased_susceptibility_to0.58186007
116MP0004133_heterotaxia0.57919132
117MP0004782_abnormal_surfactant_physiolog0.57062500
118MP0001486_abnormal_startle_reflex0.56288795
119MP0005647_abnormal_sex_gland0.55828318
120MP0010155_abnormal_intestine_physiology0.55555345
121MP0002102_abnormal_ear_morphology0.55480132
122MP0004142_abnormal_muscle_tone0.55474253
123MP0005381_digestive/alimentary_phenotyp0.55213658
124MP0003638_abnormal_response/metabolism_0.55037035
125MP0002733_abnormal_thermal_nociception0.54844116
126MP0002229_neurodegeneration0.53419798
127MP0009765_abnormal_xenobiotic_induced0.53412083
128MP0003183_abnormal_peptide_metabolism0.52314800
129MP0001661_extended_life_span0.51832913
130MP0008873_increased_physiological_sensi0.51227352
131MP0000230_abnormal_systemic_arterial0.51127440
132MP0005535_abnormal_body_temperature0.50380485
133MP0001845_abnormal_inflammatory_respons0.49158215
134MP0000462_abnormal_digestive_system0.49072937
135MP0009053_abnormal_anal_canal0.47858569
136MP0000477_abnormal_intestine_morphology0.47484179
137MP0003953_abnormal_hormone_level0.46946598
138MP0002135_abnormal_kidney_morphology0.46184089
139MP0003283_abnormal_digestive_organ0.44455600
140MP0005408_hypopigmentation0.44451775
141MP0003075_altered_response_to0.43745196
142MP0003866_abnormal_defecation0.42886472
143MP0002269_muscular_atrophy0.38969341
144MP0004947_skin_inflammation0.37411693
145MP0002876_abnormal_thyroid_physiology0.37125105
146MP0009115_abnormal_fat_cell0.37096814
147MP0005395_other_phenotype0.36192555
148MP0001849_ear_inflammation0.35711204
149MP0002796_impaired_skin_barrier0.35237558
150MP0000249_abnormal_blood_vessel0.34969295
151MP0005330_cardiomyopathy0.34582549

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)6.02371419
2Intrahepatic cholestasis (HP:0001406)5.80170055
3Abnormality of monocarboxylic acid metabolism (HP:0010996)5.75740926
4Deep venous thrombosis (HP:0002625)5.57818112
5Xanthomatosis (HP:0000991)5.55132997
6Hypobetalipoproteinemia (HP:0003563)5.49394712
7Abnormality of glutamine family amino acid metabolism (HP:0010902)4.83924605
8Hyperglycinuria (HP:0003108)4.50516137
9Prolonged partial thromboplastin time (HP:0003645)4.43725130
10Hyperammonemia (HP:0001987)4.42848473
11Hyperlipoproteinemia (HP:0010980)4.22070515
12Complement deficiency (HP:0004431)4.18905092
13Hypolipoproteinemia (HP:0010981)4.17640737
14Hemorrhage of the eye (HP:0011885)4.08987234
15Ketosis (HP:0001946)4.05563343
16Abnormality of serine family amino acid metabolism (HP:0010894)3.98090434
17Abnormality of glycine metabolism (HP:0010895)3.98090434
18Hypoglycemic coma (HP:0001325)3.93136277
19Hyperglycinemia (HP:0002154)3.80950255
20Abnormality of sulfur amino acid metabolism (HP:0004339)3.79615100
21Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.74469159
22Abnormality of fatty-acid metabolism (HP:0004359)3.73341271
23Abnormality of aspartate family amino acid metabolism (HP:0010899)3.65868300
24Fat malabsorption (HP:0002630)3.62579076
25Hypoalphalipoproteinemia (HP:0003233)3.56882543
26Joint hemorrhage (HP:0005261)3.53352377
27Gout (HP:0001997)3.48310475
28Ketoacidosis (HP:0001993)3.44948729
29Hypercholesterolemia (HP:0003124)3.42470779
30Conjugated hyperbilirubinemia (HP:0002908)3.41505285
31Epidermoid cyst (HP:0200040)3.37622298
32Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.37615250
33Abnormality of the common coagulation pathway (HP:0010990)3.33138522
34Abnormality of purine metabolism (HP:0004352)3.29172189
35Abnormality of nucleobase metabolism (HP:0010932)3.25863016
36Malnutrition (HP:0004395)3.25201910
37Abnormality of pyrimidine metabolism (HP:0004353)3.19244670
38Abnormality of complement system (HP:0005339)3.16953586
39Dicarboxylic aciduria (HP:0003215)3.05161927
40Abnormality of dicarboxylic acid metabolism (HP:0010995)3.05161927
41Cerebral palsy (HP:0100021)3.04365479
42Abnormality of the intrinsic pathway (HP:0010989)2.99044235
43Abnormality of methionine metabolism (HP:0010901)2.95576636
44Hyperbilirubinemia (HP:0002904)2.91731790
45Metabolic acidosis (HP:0001942)2.88705194
46Polyphagia (HP:0002591)2.86802177
47Delayed CNS myelination (HP:0002188)2.86065904
48Systemic lupus erythematosus (HP:0002725)2.76996675
49Late onset (HP:0003584)2.73948568
50Widely patent fontanelles and sutures (HP:0004492)2.71291966
51Abnormality of proline metabolism (HP:0010907)2.71238723
52Hydroxyprolinuria (HP:0003080)2.71238723
53Generalized aminoaciduria (HP:0002909)2.65274041
54Lethargy (HP:0001254)2.60596812
55Proximal tubulopathy (HP:0000114)2.54798221
56Skin nodule (HP:0200036)2.51769263
57Increased purine levels (HP:0004368)2.51033616
58Hyperuricemia (HP:0002149)2.51033616
59Sensorimotor neuropathy (HP:0007141)2.47562581
60Vascular calcification (HP:0004934)2.46945815
61Decreased circulating renin level (HP:0003351)2.42983577
62Myocardial infarction (HP:0001658)2.42817709
63Abnormality of serum amino acid levels (HP:0003112)2.42245399
64Glomerulonephritis (HP:0000099)2.39913848
65Irritability (HP:0000737)2.38355278
66Acanthocytosis (HP:0001927)2.37583679
67Hepatocellular carcinoma (HP:0001402)2.37540024
68Ankle clonus (HP:0011448)2.35123176
69Steatorrhea (HP:0002570)2.33355141
70Abnormality of the vitamin B12 metabolism (HP:0004341)2.32736297
71Growth hormone excess (HP:0000845)2.31401581
72Hypoglycemic seizures (HP:0002173)2.28416329
73Abnormal gallbladder physiology (HP:0012438)2.28287005
74Cholecystitis (HP:0001082)2.28287005
75Retinal atrophy (HP:0001105)2.28191422
76Alkalosis (HP:0001948)2.25541604
77Abnormal cartilage morphology (HP:0002763)2.25378380
78Abnormality of urine glucose concentration (HP:0011016)2.24980514
79Glycosuria (HP:0003076)2.24980514
80Esophageal varix (HP:0002040)2.24741922
81Spastic diplegia (HP:0001264)2.24301880
82Hyperactive renin-angiotensin system (HP:0000841)2.23812806
83Vomiting (HP:0002013)2.22189112
84Pigmentary retinal degeneration (HP:0001146)2.22130237
85Abnormality of vitamin B metabolism (HP:0004340)2.20429780
86Cardiovascular calcification (HP:0011915)2.18396747
87Confusion (HP:0001289)2.16974226
88Abnormality of transition element cation homeostasis (HP:0011030)2.15375890
89Cerebral edema (HP:0002181)2.13437207
90Cholelithiasis (HP:0001081)2.11214379
91Ileus (HP:0002595)2.11125809
92Pancreatitis (HP:0001733)2.10401337
93Hyperphosphaturia (HP:0003109)2.10291524
94Spontaneous abortion (HP:0005268)2.09905878
95Neonatal onset (HP:0003623)2.08265371
96Metabolic alkalosis (HP:0200114)2.06975957
97Recurrent gram-negative bacterial infections (HP:0005420)2.05845545
98Abnormal gallbladder morphology (HP:0012437)2.05124698
99Nausea (HP:0002018)2.05112802
100Abnormality of renin-angiotensin system (HP:0000847)2.04576742
101Potter facies (HP:0002009)2.04552699
102Facial shape deformation (HP:0011334)2.04552699
103Abnormality of iron homeostasis (HP:0011031)2.03983575
104Abnormal enzyme/coenzyme activity (HP:0012379)2.03851608
105Right ventricular cardiomyopathy (HP:0011663)2.03464624
106Nephrolithiasis (HP:0000787)2.01844390
107Enlarged kidneys (HP:0000105)1.99758375
108Amyloidosis (HP:0011034)1.97991731
109Abnormality of vitamin metabolism (HP:0100508)1.95359984
110Abnormal urine phosphate concentration (HP:0012599)1.93028042
111Brushfield spots (HP:0001088)1.89104043
112Abnormal eating behavior (HP:0100738)1.87672262
113Poikilocytosis (HP:0004447)1.86925486
114Vacuolated lymphocytes (HP:0001922)1.85138761
115Abnormality of alkaline phosphatase activity (HP:0004379)1.84912649
116Hyperinsulinemic hypoglycemia (HP:0000825)1.84776252
117Polycythemia (HP:0001901)1.84721144
118Increased serum pyruvate (HP:0003542)1.83622188
119Rhabdomyolysis (HP:0003201)1.82675570
120Nephritis (HP:0000123)1.82218523
121Myoglobinuria (HP:0002913)1.82157596
122Abnormality of the vitreous humor (HP:0004327)1.80386713
123Axonal loss (HP:0003447)1.79738840
124Hypophosphatemia (HP:0002148)1.79575752
125Wide cranial sutures (HP:0010537)1.77833134
126Rickets (HP:0002748)1.75380773
127Chronic diarrhea (HP:0002028)1.72396630
128Abdominal distention (HP:0003270)1.71850931
129Reticulocytosis (HP:0001923)1.70169200
130Joint swelling (HP:0001386)1.66311037
131Abnormal tarsal ossification (HP:0008369)1.65203371
132Abnormality of glycolysis (HP:0004366)1.63951104
133Myopathic facies (HP:0002058)1.63548228
134Elevated alkaline phosphatase (HP:0003155)1.62026348

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK5.01395137
2ERN14.05212352
3MST1R3.88251856
4TRIB33.43204351
5PKN23.27979387
6FGFR43.12008180
7SIK12.46763691
8MARK12.30997944
9MAP3K102.25658091
10EPHA42.24470477
11SIK22.20931898
12TAOK32.15367212
13FLT32.01352966
14MAP3K111.86706188
15PTK61.86526253
16NEK11.75935661
17MAP2K21.68988271
18CASK1.64272153
19GRK61.61789887
20PIK3CA1.61029358
21LMTK21.55127016
22INSRR1.54011837
23MAP4K21.49250593
24PHKG11.48558994
25PHKG21.48558994
26MAPK111.44463851
27RIPK11.43319519
28TYK21.41608689
29FRK1.39409494
30PRKG21.37763517
31KSR21.36754009
32TBK11.36274199
33TYRO31.23974841
34MYLK1.23884877
35TXK1.23865249
36NTRK31.20461706
37EPHA31.20413166
38PIK3CG1.13251017
39DYRK21.12421449
40KDR1.11904748
41NME11.10286557
42TGFBR21.09361708
43ERBB21.09119244
44MAP2K71.08555982
45TESK11.07251429
46NTRK21.07009644
47WNK31.06946548
48MAP2K31.06500585
49MAP3K31.04556373
50DYRK1B1.04474017
51WNK41.03316185
52IRAK31.02912305
53EPHB11.02679478
54MET1.02256095
55ERBB41.01852589
56MAP3K71.00661590
57TIE10.99634784
58MAP3K40.98818802
59PRKD30.97296839
60EPHA20.96915827
61MAPK130.95135026
62ACVR1B0.94210401
63MAP4K10.93611004
64JAK20.93234606
65ABL20.93092102
66PRKAA20.92433898
67FGFR30.90918218
68MAP2K10.90243955
69EPHB20.88190587
70ICK0.86833716
71LRRK20.85459841
72MAP3K20.84618963
73BCR0.84017604
74RET0.83989566
75PAK40.83515257
76CAMKK10.82848479
77EEF2K0.82743610
78CAMK1D0.79815609
79CDK190.79690078
80MARK20.79489659
81GRK10.79165177
82TTN0.74171790
83PRKAA10.73651522
84SGK2230.73150552
85SGK4940.73150552
86RPS6KA20.73124983
87PTK20.71144997
88TAOK10.70437594
89KIT0.67856632
90MAP2K40.66894641
91TLK10.66700881
92CDK50.66658717
93MAP3K10.66082488
94NTRK10.65718229
95MAPK150.65177380
96PDK40.64543239
97PDK30.64543239
98MAP3K60.63602936
99NME20.62852159
100NEK90.62303801
101MUSK0.61474753
102MAPK40.58859301
103DYRK1A0.58600773
104ZAP700.58231030
105CSF1R0.57907808
106PINK10.57298419
107PRKCZ0.56919167
108UHMK10.55822793
109FES0.55296630
110PRKACG0.54045590
111PAK60.52754266
112BLK0.52585928
113MAP2K60.52496748
114PDPK10.52092950
115OXSR10.51862557
116ADRBK20.51685786
117GSK3A0.51029994
118SRC0.50379844
119TESK20.49465497
120MATK0.48904805
121JAK10.48680705
122FYN0.47776997
123STK390.47274391
124MTOR0.46092327
125CDC42BPA0.45932443
126PRKCG0.45775430
127MAP3K80.44648900
128TNK20.44466211
129ITK0.44395641
130PIM20.43587276
131LIMK10.43440190
132SIK30.43029797
133PRKCA0.42367997
134RPS6KB20.41973256
135MAPKAPK30.39417904
136CSK0.37014455
137CAMK2G0.36813688
138CDK60.36700306
139DAPK30.35964965
140MAPK120.35839097
141PDK20.32643761
142PAK30.31861185
143PDGFRA0.31243375
144BTK0.29483696
145DAPK20.29222377
146AKT20.28179828
147PDK10.28093211
148CAMK40.26821891
149TGFBR10.26252051

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.66073786
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.37943965
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.93756775
4Nitrogen metabolism_Homo sapiens_hsa009102.83615435
5Arginine biosynthesis_Homo sapiens_hsa002202.81317607
6Tryptophan metabolism_Homo sapiens_hsa003802.65026107
7Fatty acid degradation_Homo sapiens_hsa000712.60858834
8Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.58370293
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.46478068
10Pentose and glucuronate interconversions_Homo sapiens_hsa000402.35474584
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.22124516
12Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.17319739
13Complement and coagulation cascades_Homo sapiens_hsa046102.12900230
142-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.12637191
15Butanoate metabolism_Homo sapiens_hsa006502.11933032
16Peroxisome_Homo sapiens_hsa041462.00916510
17Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.97709471
18Propanoate metabolism_Homo sapiens_hsa006401.93890471
19PPAR signaling pathway_Homo sapiens_hsa033201.91684321
20Fat digestion and absorption_Homo sapiens_hsa049751.90515668
21Caffeine metabolism_Homo sapiens_hsa002321.88154557
22Sulfur metabolism_Homo sapiens_hsa009201.87351668
23Histidine metabolism_Homo sapiens_hsa003401.84343453
24Drug metabolism - other enzymes_Homo sapiens_hsa009831.75429258
25Chemical carcinogenesis_Homo sapiens_hsa052041.73281903
26Fatty acid metabolism_Homo sapiens_hsa012121.72994904
27Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.72807301
28Bile secretion_Homo sapiens_hsa049761.71521138
29Starch and sucrose metabolism_Homo sapiens_hsa005001.68446445
30Folate biosynthesis_Homo sapiens_hsa007901.66440441
31beta-Alanine metabolism_Homo sapiens_hsa004101.65970723
32Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.59059476
33Pyruvate metabolism_Homo sapiens_hsa006201.56012258
34Selenocompound metabolism_Homo sapiens_hsa004501.52641169
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52404206
36Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.50968199
37Carbon metabolism_Homo sapiens_hsa012001.48621552
38Steroid hormone biosynthesis_Homo sapiens_hsa001401.45057700
39Retinol metabolism_Homo sapiens_hsa008301.43822357
40Vitamin digestion and absorption_Homo sapiens_hsa049771.43787713
41Staphylococcus aureus infection_Homo sapiens_hsa051501.43497143
42Biosynthesis of amino acids_Homo sapiens_hsa012301.37939299
43Phenylalanine metabolism_Homo sapiens_hsa003601.35863934
44Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.32600086
45Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.32267005
46Maturity onset diabetes of the young_Homo sapiens_hsa049501.30494315
47Cyanoamino acid metabolism_Homo sapiens_hsa004601.28787220
48Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.24341354
49Cysteine and methionine metabolism_Homo sapiens_hsa002701.21786793
50Sulfur relay system_Homo sapiens_hsa041221.19606004
51ABC transporters_Homo sapiens_hsa020101.14643590
52Arginine and proline metabolism_Homo sapiens_hsa003301.12706291
53Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.08931875
54Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.07658571
55Tyrosine metabolism_Homo sapiens_hsa003501.07037695
56Galactose metabolism_Homo sapiens_hsa000521.03291612
57Glutathione metabolism_Homo sapiens_hsa004800.97120089
58Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.96326151
59Glycerolipid metabolism_Homo sapiens_hsa005610.94449742
60Fructose and mannose metabolism_Homo sapiens_hsa000510.93189493
61Pentose phosphate pathway_Homo sapiens_hsa000300.90990847
62Fatty acid elongation_Homo sapiens_hsa000620.89419786
63Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.80027079
64Lysine degradation_Homo sapiens_hsa003100.79434665
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.76849558
66Vitamin B6 metabolism_Homo sapiens_hsa007500.71332460
67Ether lipid metabolism_Homo sapiens_hsa005650.66742369
68Mineral absorption_Homo sapiens_hsa049780.60882053
69Steroid biosynthesis_Homo sapiens_hsa001000.58449339
70Renin-angiotensin system_Homo sapiens_hsa046140.50644054
71Metabolic pathways_Homo sapiens_hsa011000.50090157
72Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45905049
73Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.39114124
74Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37696126
75Insulin resistance_Homo sapiens_hsa049310.35029655
76Cocaine addiction_Homo sapiens_hsa050300.33909503
77One carbon pool by folate_Homo sapiens_hsa006700.30378945
78Sphingolipid metabolism_Homo sapiens_hsa006000.29937930
79Insulin secretion_Homo sapiens_hsa049110.29542343
80Glycosaminoglycan degradation_Homo sapiens_hsa005310.28383271
81Glycerophospholipid metabolism_Homo sapiens_hsa005640.28282532
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.26249742
83alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.25918410
84Adipocytokine signaling pathway_Homo sapiens_hsa049200.23945746
85Fatty acid biosynthesis_Homo sapiens_hsa000610.20240079
86Synaptic vesicle cycle_Homo sapiens_hsa047210.19777865
87Prion diseases_Homo sapiens_hsa050200.19179727
88Other glycan degradation_Homo sapiens_hsa005110.16302787
89Lysosome_Homo sapiens_hsa041420.15855209
90Protein digestion and absorption_Homo sapiens_hsa049740.13207796
91Amphetamine addiction_Homo sapiens_hsa050310.13145375
92GABAergic synapse_Homo sapiens_hsa047270.12585926
93Nicotine addiction_Homo sapiens_hsa050330.12430303
94Serotonergic synapse_Homo sapiens_hsa047260.12213218
95Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.12024167
96Ovarian steroidogenesis_Homo sapiens_hsa049130.10684793
97Linoleic acid metabolism_Homo sapiens_hsa005910.09635978
98Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.09239625
99Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.08997551
100AMPK signaling pathway_Homo sapiens_hsa041520.08908425
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.08367518
102Dopaminergic synapse_Homo sapiens_hsa047280.07630046
103Glucagon signaling pathway_Homo sapiens_hsa049220.07167820
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.02090187
105Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601-0.1799268
106Legionellosis_Homo sapiens_hsa05134-0.1703197
107Regulation of autophagy_Homo sapiens_hsa04140-0.1621049
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512-0.1572740
109Terpenoid backbone biosynthesis_Homo sapiens_hsa00900-0.1167355
110Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1055707
111Hepatitis C_Homo sapiens_hsa05160-0.0893523
112Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.0733672
113Thyroid hormone synthesis_Homo sapiens_hsa04918-0.0626015
114Bladder cancer_Homo sapiens_hsa05219-0.0396459
115Insulin signaling pathway_Homo sapiens_hsa04910-0.0116553

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