Rank | Gene Set | Z-score |
---|---|---|
1 | central nervous system myelination (GO:0022010) | 7.18941975 |
2 | axon ensheathment in central nervous system (GO:0032291) | 7.18941975 |
3 | short-term memory (GO:0007614) | 6.71627686 |
4 | negative regulation of execution phase of apoptosis (GO:1900118) | 6.37871333 |
5 | presynaptic membrane assembly (GO:0097105) | 5.88561679 |
6 | presynaptic membrane organization (GO:0097090) | 5.37104614 |
7 | synaptic vesicle maturation (GO:0016188) | 5.14394571 |
8 | postsynaptic membrane organization (GO:0001941) | 5.13896375 |
9 | positive regulation of protein kinase C signaling (GO:0090037) | 4.97603886 |
10 | glutamate secretion (GO:0014047) | 4.96751013 |
11 | synaptic vesicle exocytosis (GO:0016079) | 4.69051891 |
12 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 4.61834429 |
13 | neuron cell-cell adhesion (GO:0007158) | 4.55232425 |
14 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.43789130 |
15 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.42760804 |
16 | metanephric tubule development (GO:0072170) | 4.41542992 |
17 | metanephric nephron tubule development (GO:0072234) | 4.41542992 |
18 | retina layer formation (GO:0010842) | 4.39438027 |
19 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.39063415 |
20 | limb bud formation (GO:0060174) | 4.36631606 |
21 | gamma-aminobutyric acid transport (GO:0015812) | 4.35659055 |
22 | vocalization behavior (GO:0071625) | 4.33325530 |
23 | L-amino acid import (GO:0043092) | 4.30855118 |
24 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.23982600 |
25 | cilium or flagellum-dependent cell motility (GO:0001539) | 4.23538129 |
26 | neurotransmitter secretion (GO:0007269) | 4.17395335 |
27 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.11709308 |
28 | synaptic transmission, glutamatergic (GO:0035249) | 4.10380575 |
29 | oligodendrocyte differentiation (GO:0048709) | 4.02556396 |
30 | metanephric nephron epithelium development (GO:0072243) | 4.01381194 |
31 | neuron-neuron synaptic transmission (GO:0007270) | 3.99694333 |
32 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.95713563 |
33 | regulation of timing of cell differentiation (GO:0048505) | 3.88072400 |
34 | eyelid development in camera-type eye (GO:0061029) | 3.82265579 |
35 | regulation of synaptic vesicle transport (GO:1902803) | 3.82014964 |
36 | cellular potassium ion homeostasis (GO:0030007) | 3.76549413 |
37 | metanephric epithelium development (GO:0072207) | 3.75877517 |
38 | photoreceptor cell differentiation (GO:0046530) | 3.75389551 |
39 | eye photoreceptor cell differentiation (GO:0001754) | 3.75389551 |
40 | neuronal ion channel clustering (GO:0045161) | 3.74273579 |
41 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.74171847 |
42 | neuronal action potential propagation (GO:0019227) | 3.72099049 |
43 | amino acid import (GO:0043090) | 3.71795665 |
44 | glutamate receptor signaling pathway (GO:0007215) | 3.71435699 |
45 | GMP metabolic process (GO:0046037) | 3.65910465 |
46 | cochlea development (GO:0090102) | 3.63637233 |
47 | locomotory exploration behavior (GO:0035641) | 3.62654000 |
48 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.58402282 |
49 | cerebellar granule cell differentiation (GO:0021707) | 3.56684312 |
50 | neurotransmitter transport (GO:0006836) | 3.51218317 |
51 | auditory behavior (GO:0031223) | 3.49863669 |
52 | exploration behavior (GO:0035640) | 3.47280628 |
53 | sodium ion export (GO:0071436) | 3.44798469 |
54 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.44386016 |
55 | neurotransmitter uptake (GO:0001504) | 3.42643539 |
56 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.39918332 |
57 | regulation of neurotransmitter levels (GO:0001505) | 3.39746231 |
58 | myelination (GO:0042552) | 3.36354054 |
59 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.34327169 |
60 | axon ensheathment (GO:0008366) | 3.33069363 |
61 | ensheathment of neurons (GO:0007272) | 3.33069363 |
62 | axonemal dynein complex assembly (GO:0070286) | 3.32988323 |
63 | facial nerve structural organization (GO:0021612) | 3.32971449 |
64 | regulation of development, heterochronic (GO:0040034) | 3.32077648 |
65 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.32070366 |
66 | fatty acid elongation (GO:0030497) | 3.32024267 |
67 | acidic amino acid transport (GO:0015800) | 3.30317368 |
68 | cilium movement (GO:0003341) | 3.28191749 |
69 | dendritic spine morphogenesis (GO:0060997) | 3.27837049 |
70 | nephron epithelium development (GO:0072009) | 3.26594318 |
71 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.25093615 |
72 | cranial nerve structural organization (GO:0021604) | 3.24774571 |
73 | response to auditory stimulus (GO:0010996) | 3.24145955 |
74 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.23997053 |
75 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.23596460 |
76 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.18039187 |
77 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 3.17618018 |
78 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 3.17618018 |
79 | regulation of synapse structural plasticity (GO:0051823) | 3.15157594 |
80 | negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) | 3.15124924 |
81 | nephron tubule development (GO:0072080) | 3.14908576 |
82 | C4-dicarboxylate transport (GO:0015740) | 3.14316975 |
83 | melanin metabolic process (GO:0006582) | 3.12828631 |
84 | regulation of protein kinase A signaling (GO:0010738) | 3.12147286 |
85 | glycosphingolipid biosynthetic process (GO:0006688) | 3.12022235 |
86 | melanin biosynthetic process (GO:0042438) | 3.11663568 |
87 | establishment of mitochondrion localization (GO:0051654) | 3.11165068 |
88 | positive regulation of dendritic spine development (GO:0060999) | 3.10540877 |
89 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.09670739 |
90 | positive regulation of calcium ion import (GO:0090280) | 3.08550078 |
91 | tachykinin receptor signaling pathway (GO:0007217) | 3.07504831 |
92 | regulation of neurotransmitter secretion (GO:0046928) | 3.07333183 |
93 | retinal cone cell development (GO:0046549) | 3.05004448 |
94 | potassium ion import (GO:0010107) | 3.02944524 |
95 | positive regulation of synapse maturation (GO:0090129) | 3.02802718 |
96 | enteric nervous system development (GO:0048484) | 3.02568815 |
97 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.01230363 |
98 | organ growth (GO:0035265) | 3.01177612 |
99 | mechanosensory behavior (GO:0007638) | 3.01086092 |
100 | epithelial cilium movement (GO:0003351) | 3.00765923 |
101 | positive regulation of membrane potential (GO:0045838) | 3.00097331 |
102 | response to histamine (GO:0034776) | 2.98966875 |
103 | axonal fasciculation (GO:0007413) | 2.98857565 |
104 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.98288391 |
105 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.96275898 |
106 | potassium ion homeostasis (GO:0055075) | 2.95928264 |
107 | layer formation in cerebral cortex (GO:0021819) | 2.95141202 |
108 | long-term synaptic potentiation (GO:0060291) | 2.95041034 |
109 | negative regulation of neurotransmitter transport (GO:0051589) | 2.94824259 |
110 | adult walking behavior (GO:0007628) | 2.94716705 |
111 | regulation of postsynaptic membrane potential (GO:0060078) | 2.94571975 |
112 | regulation of pigment cell differentiation (GO:0050932) | 2.94388010 |
113 | regulation of neurotransmitter transport (GO:0051588) | 2.93986956 |
114 | negative regulation of protein localization to cell surface (GO:2000009) | 2.93686772 |
115 | innervation (GO:0060384) | 2.93622491 |
116 | membrane depolarization during action potential (GO:0086010) | 2.93401882 |
117 | collecting duct development (GO:0072044) | 2.93275191 |
118 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.93196751 |
119 | proline transport (GO:0015824) | 2.91808066 |
120 | cranial nerve morphogenesis (GO:0021602) | 2.91635191 |
121 | L-glutamate transport (GO:0015813) | 2.91559606 |
122 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.90804829 |
123 | synaptic transmission (GO:0007268) | 2.89080907 |
124 | transmission of nerve impulse (GO:0019226) | 2.88510331 |
125 | positive regulation of cellular amine metabolic process (GO:0033240) | 2.87798112 |
126 | long-term memory (GO:0007616) | 2.87304211 |
127 | nucleobase catabolic process (GO:0046113) | 2.87050373 |
128 | negative regulation of peptidyl-threonine phosphorylation (GO:0010801) | 2.86807446 |
129 | neuromuscular synaptic transmission (GO:0007274) | 2.86039068 |
130 | synaptic vesicle endocytosis (GO:0048488) | 2.85780993 |
131 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.85257252 |
132 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 2.85063302 |
133 | regulation of protein kinase C signaling (GO:0090036) | 2.84782995 |
134 | regulation of vesicle fusion (GO:0031338) | 2.84074902 |
135 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.83764633 |
136 | synapse assembly (GO:0007416) | 2.83756850 |
137 | renal tubule development (GO:0061326) | 2.82205814 |
138 | cellular sodium ion homeostasis (GO:0006883) | 2.81672518 |
139 | righting reflex (GO:0060013) | 2.81546041 |
140 | cranial nerve development (GO:0021545) | 2.80044818 |
141 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.79994406 |
142 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.78290019 |
143 | neuron remodeling (GO:0016322) | 2.76701880 |
144 | spinal cord motor neuron differentiation (GO:0021522) | 2.76326400 |
145 | positive regulation of synapse assembly (GO:0051965) | 2.75481689 |
146 | regulation of somitogenesis (GO:0014807) | 2.73373848 |
147 | mesonephros development (GO:0001823) | 2.73200561 |
148 | secondary metabolite biosynthetic process (GO:0044550) | 2.72611061 |
149 | positive regulation of protein tyrosine kinase activity (GO:0061098) | 2.72053621 |
150 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.70735671 |
151 | regulation of catecholamine metabolic process (GO:0042069) | 2.69601504 |
152 | regulation of dopamine metabolic process (GO:0042053) | 2.69601504 |
153 | otic vesicle formation (GO:0030916) | 2.66917643 |
154 | membrane assembly (GO:0071709) | 2.65594150 |
155 | calcium ion import (GO:0070509) | 2.64677054 |
156 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 2.64318575 |
157 | import into cell (GO:0098657) | 2.64272606 |
158 | nonmotile primary cilium assembly (GO:0035058) | 2.58822825 |
159 | protein localization to synapse (GO:0035418) | 2.57920811 |
160 | sympathetic nervous system development (GO:0048485) | 2.57631310 |
161 | neuron recognition (GO:0008038) | 2.57339074 |
162 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.55717623 |
163 | regulation of neuron projection regeneration (GO:0070570) | 2.55561850 |
164 | regulation of axon regeneration (GO:0048679) | 2.55561850 |
165 | photoreceptor cell maintenance (GO:0045494) | 2.54878241 |
166 | dopamine biosynthetic process (GO:0042416) | 2.54107553 |
167 | lymphoid progenitor cell differentiation (GO:0002320) | 2.53036961 |
168 | startle response (GO:0001964) | 2.52831047 |
169 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.52774489 |
170 | glial cell differentiation (GO:0010001) | 2.51978435 |
171 | GPI anchor biosynthetic process (GO:0006506) | 2.51771328 |
172 | developmental pigmentation (GO:0048066) | 2.51614040 |
173 | protein palmitoylation (GO:0018345) | 2.50658891 |
174 | cell differentiation in spinal cord (GO:0021515) | 2.50629063 |
175 | magnesium ion transport (GO:0015693) | 2.49341146 |
176 | branch elongation of an epithelium (GO:0060602) | 2.47526290 |
177 | Sertoli cell development (GO:0060009) | 2.46443937 |
178 | regulation of feeding behavior (GO:0060259) | 2.45715233 |
179 | response to methylmercury (GO:0051597) | 2.45493312 |
180 | spinal cord association neuron differentiation (GO:0021527) | 2.45450939 |
181 | anatomical structure arrangement (GO:0048532) | 2.43703185 |
182 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 2.41383960 |
183 | keratinocyte development (GO:0003334) | 2.41004271 |
184 | cornea development in camera-type eye (GO:0061303) | 2.40152734 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.12070550 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.17753158 |
3 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.02785285 |
4 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.89319949 |
5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.80109350 |
6 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.76126115 |
7 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.74628222 |
8 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.65117918 |
9 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.57425765 |
10 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.53922308 |
11 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.53922308 |
12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.53403839 |
13 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.47441932 |
14 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.45770390 |
15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.44121299 |
16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.42260328 |
17 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.39998287 |
18 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.32081912 |
19 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.31871595 |
20 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.29897314 |
21 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.26358290 |
22 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.22916378 |
23 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 2.15744510 |
24 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.15247525 |
25 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.14019101 |
26 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.11140538 |
27 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 2.08018020 |
28 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.07694784 |
29 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 2.05224493 |
30 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.95452042 |
31 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.95080018 |
32 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.91467764 |
33 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.85135803 |
34 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.80996221 |
35 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.72120607 |
36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.68657510 |
37 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.64715555 |
38 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.62738725 |
39 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.60958607 |
40 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.59882704 |
41 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.58207111 |
42 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.57886643 |
43 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.56626389 |
44 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.56447454 |
45 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.54919034 |
46 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.54265593 |
47 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.51573697 |
48 | P300_19829295_ChIP-Seq_ESCs_Human | 1.51310082 |
49 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.47700177 |
50 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.46288476 |
51 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.45584556 |
52 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.43100417 |
53 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.42432631 |
54 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.42189132 |
55 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.37989702 |
56 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.37051260 |
57 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.35659193 |
58 | AR_25329375_ChIP-Seq_VCAP_Human | 1.33453561 |
59 | FUS_26573619_Chip-Seq_HEK293_Human | 1.33344255 |
60 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.30056161 |
61 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.29444590 |
62 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.28380581 |
63 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.27828025 |
64 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.27612630 |
65 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.27274415 |
66 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.26914580 |
67 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.26539597 |
68 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.25754731 |
69 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.25280920 |
70 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.25079932 |
71 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 1.24010278 |
72 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.23701416 |
73 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.23631517 |
74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.21021715 |
75 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.20003269 |
76 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.19137064 |
77 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.17927847 |
78 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.17927847 |
79 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.17612111 |
80 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.17482937 |
81 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.17044506 |
82 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.16834954 |
83 | AR_19668381_ChIP-Seq_PC3_Human | 1.16595446 |
84 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.16244474 |
85 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.16068220 |
86 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.15858126 |
87 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.15844430 |
88 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12582937 |
89 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.12191634 |
90 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.12032600 |
91 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.11996075 |
92 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.11179747 |
93 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.09968855 |
94 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.09351401 |
95 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.09078016 |
96 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.07444324 |
97 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.06851857 |
98 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.06375544 |
99 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.05072825 |
100 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.04706676 |
101 | EWS_26573619_Chip-Seq_HEK293_Human | 1.03994737 |
102 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.03759558 |
103 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.02755896 |
104 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.02679041 |
105 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.01947151 |
106 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.00467795 |
107 | KDM2B_26808549_Chip-Seq_REH_Human | 1.00338572 |
108 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.00217514 |
109 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.99478233 |
110 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.99478233 |
111 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.98877983 |
112 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98385746 |
113 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97539252 |
114 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.97495115 |
115 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.97079779 |
116 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96623783 |
117 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.96141650 |
118 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.95944618 |
119 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.95702098 |
120 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95259626 |
121 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.95206043 |
122 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.94312814 |
123 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 0.93423393 |
124 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.93300054 |
125 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.92874480 |
126 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.92351265 |
127 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.92275179 |
128 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.89759794 |
129 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.88724907 |
130 | * STAT3_23295773_ChIP-Seq_U87_Human | 0.88716272 |
131 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.88368990 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003136_yellow_coat_color | 7.06407891 |
2 | MP0005409_darkened_coat_color | 4.81968080 |
3 | MP0004381_abnormal_hair_follicle | 4.56904142 |
4 | MP0001188_hyperpigmentation | 4.51217590 |
5 | MP0003880_abnormal_central_pattern | 4.10750386 |
6 | MP0001984_abnormal_olfaction | 2.79635190 |
7 | MP0004742_abnormal_vestibular_system | 2.51337151 |
8 | MP0005423_abnormal_somatic_nervous | 2.39496556 |
9 | MP0009379_abnormal_foot_pigmentation | 2.31051490 |
10 | MP0006292_abnormal_olfactory_placode | 2.20156042 |
11 | MP0005171_absent_coat_pigmentation | 2.07466656 |
12 | MP0000920_abnormal_myelination | 1.97425840 |
13 | MP0008877_abnormal_DNA_methylation | 1.94979269 |
14 | MP0002822_catalepsy | 1.93681005 |
15 | MP0001968_abnormal_touch/_nociception | 1.93508351 |
16 | MP0002102_abnormal_ear_morphology | 1.92459549 |
17 | MP0005174_abnormal_tail_pigmentation | 1.90032438 |
18 | MP0001486_abnormal_startle_reflex | 1.90020484 |
19 | MP0002272_abnormal_nervous_system | 1.81720050 |
20 | MP0000566_synostosis | 1.80821474 |
21 | MP0003690_abnormal_glial_cell | 1.78376895 |
22 | MP0000015_abnormal_ear_pigmentation | 1.72960801 |
23 | MP0004270_analgesia | 1.72646272 |
24 | MP0004142_abnormal_muscle_tone | 1.65226018 |
25 | MP0003122_maternal_imprinting | 1.61170379 |
26 | MP0005386_behavior/neurological_phenoty | 1.58915050 |
27 | MP0004924_abnormal_behavior | 1.58915050 |
28 | MP0003633_abnormal_nervous_system | 1.58843375 |
29 | MP0000778_abnormal_nervous_system | 1.56501603 |
30 | MP0003879_abnormal_hair_cell | 1.56468740 |
31 | MP0003787_abnormal_imprinting | 1.51111408 |
32 | MP0004811_abnormal_neuron_physiology | 1.50692139 |
33 | MP0003938_abnormal_ear_development | 1.50454524 |
34 | MP0005379_endocrine/exocrine_gland_phen | 1.49085234 |
35 | MP0003941_abnormal_skin_development | 1.48519104 |
36 | MP0009745_abnormal_behavioral_response | 1.48059875 |
37 | MP0000631_abnormal_neuroendocrine_gland | 1.42794580 |
38 | MP0002067_abnormal_sensory_capabilities | 1.42311758 |
39 | MP0002249_abnormal_larynx_morphology | 1.39970058 |
40 | MP0002064_seizures | 1.37400560 |
41 | MP0003631_nervous_system_phenotype | 1.34561833 |
42 | MP0002734_abnormal_mechanical_nocicepti | 1.34479177 |
43 | MP0002638_abnormal_pupillary_reflex | 1.34259398 |
44 | MP0002177_abnormal_outer_ear | 1.34116257 |
45 | MP0003635_abnormal_synaptic_transmissio | 1.33797050 |
46 | MP0001905_abnormal_dopamine_level | 1.33618935 |
47 | MP0009780_abnormal_chondrocyte_physiolo | 1.31326074 |
48 | MP0005551_abnormal_eye_electrophysiolog | 1.30588109 |
49 | MP0009250_abnormal_appendicular_skeleto | 1.30054769 |
50 | MP0001986_abnormal_taste_sensitivity | 1.28516213 |
51 | MP0006072_abnormal_retinal_apoptosis | 1.27300567 |
52 | MP0001970_abnormal_pain_threshold | 1.26118698 |
53 | MP0002653_abnormal_ependyma_morphology | 1.25802978 |
54 | MP0003329_amyloid_beta_deposits | 1.25331425 |
55 | MP0000569_abnormal_digit_pigmentation | 1.22309011 |
56 | MP0000026_abnormal_inner_ear | 1.22019066 |
57 | MP0005645_abnormal_hypothalamus_physiol | 1.21936463 |
58 | MP0000049_abnormal_middle_ear | 1.19680588 |
59 | MP0006276_abnormal_autonomic_nervous | 1.18482536 |
60 | MP0008260_abnormal_autophagy | 1.17203497 |
61 | MP0003011_delayed_dark_adaptation | 1.16102875 |
62 | MP0003724_increased_susceptibility_to | 1.15124575 |
63 | MP0009046_muscle_twitch | 1.12809669 |
64 | MP0002752_abnormal_somatic_nervous | 1.12216970 |
65 | MP0003632_abnormal_nervous_system | 1.10754096 |
66 | MP0002277_abnormal_respiratory_mucosa | 1.10048532 |
67 | MP0003121_genomic_imprinting | 1.08536969 |
68 | MP0000613_abnormal_salivary_gland | 1.06584991 |
69 | MP0001963_abnormal_hearing_physiology | 1.06291063 |
70 | MP0001177_atelectasis | 1.04870066 |
71 | MP0002751_abnormal_autonomic_nervous | 1.04016721 |
72 | MP0005646_abnormal_pituitary_gland | 1.03804009 |
73 | MP0000762_abnormal_tongue_morphology | 1.02221465 |
74 | MP0002557_abnormal_social/conspecific_i | 1.01733284 |
75 | MP0001346_abnormal_lacrimal_gland | 1.01418892 |
76 | MP0001485_abnormal_pinna_reflex | 1.01140436 |
77 | MP0004145_abnormal_muscle_electrophysio | 1.00843777 |
78 | MP0001502_abnormal_circadian_rhythm | 1.00234919 |
79 | MP0002184_abnormal_innervation | 1.00053055 |
80 | MP0002572_abnormal_emotion/affect_behav | 0.99910780 |
81 | MP0000467_abnormal_esophagus_morphology | 0.99549611 |
82 | MP0002882_abnormal_neuron_morphology | 0.98881516 |
83 | MP0001340_abnormal_eyelid_morphology | 0.97680892 |
84 | MP0002229_neurodegeneration | 0.96864469 |
85 | MP0004859_abnormal_synaptic_plasticity | 0.96705195 |
86 | MP0004147_increased_porphyrin_level | 0.96073421 |
87 | MP0001501_abnormal_sleep_pattern | 0.95103592 |
88 | MP0002938_white_spotting | 0.94180327 |
89 | MP0002733_abnormal_thermal_nociception | 0.93978697 |
90 | MP0005499_abnormal_olfactory_system | 0.92263548 |
91 | MP0005394_taste/olfaction_phenotype | 0.92263548 |
92 | MP0002909_abnormal_adrenal_gland | 0.91766400 |
93 | MP0010386_abnormal_urinary_bladder | 0.91723136 |
94 | MP0000462_abnormal_digestive_system | 0.91421869 |
95 | MP0003950_abnormal_plasma_membrane | 0.91179591 |
96 | MP0008569_lethality_at_weaning | 0.90808099 |
97 | MP0001529_abnormal_vocalization | 0.90538809 |
98 | MP0003937_abnormal_limbs/digits/tail_de | 0.90461060 |
99 | MP0002163_abnormal_gland_morphology | 0.88750629 |
100 | MP0000579_abnormal_nail_morphology | 0.87792008 |
101 | MP0002095_abnormal_skin_pigmentation | 0.87722870 |
102 | MP0003634_abnormal_glial_cell | 0.87248143 |
103 | MP0003315_abnormal_perineum_morphology | 0.87150586 |
104 | MP0004885_abnormal_endolymph | 0.86669913 |
105 | MP0000383_abnormal_hair_follicle | 0.86416195 |
106 | MP0005187_abnormal_penis_morphology | 0.86334277 |
107 | MP0002735_abnormal_chemical_nociception | 0.86299285 |
108 | MP0000955_abnormal_spinal_cord | 0.86154565 |
109 | MP0004133_heterotaxia | 0.85332757 |
110 | MP0005595_abnormal_vascular_smooth | 0.83732119 |
111 | MP0002069_abnormal_eating/drinking_beha | 0.83532022 |
112 | MP0008872_abnormal_physiological_respon | 0.79716177 |
113 | MP0002736_abnormal_nociception_after | 0.78681754 |
114 | MP0005075_abnormal_melanosome_morpholog | 0.78114184 |
115 | MP0005195_abnormal_posterior_eye | 0.76717026 |
116 | MP0002063_abnormal_learning/memory/cond | 0.76007223 |
117 | MP0000647_abnormal_sebaceous_gland | 0.75528640 |
118 | MP0001440_abnormal_grooming_behavior | 0.75229666 |
119 | MP0008875_abnormal_xenobiotic_pharmacok | 0.74547884 |
120 | MP0002066_abnormal_motor_capabilities/c | 0.73886905 |
121 | MP0005253_abnormal_eye_physiology | 0.73258040 |
122 | MP0002928_abnormal_bile_duct | 0.72510503 |
123 | MP0003698_abnormal_male_reproductive | 0.72031833 |
124 | MP0003123_paternal_imprinting | 0.71754627 |
125 | MP0001661_extended_life_span | 0.69675999 |
126 | MP0001299_abnormal_eye_distance/ | 0.69431974 |
127 | MP0003385_abnormal_body_wall | 0.67511921 |
128 | MP0002090_abnormal_vision | 0.65195293 |
129 | MP0001664_abnormal_digestion | 0.64988171 |
130 | MP0003195_calcinosis | 0.64678095 |
131 | MP0005167_abnormal_blood-brain_barrier | 0.63752474 |
132 | MP0004043_abnormal_pH_regulation | 0.63534995 |
133 | MP0008874_decreased_physiological_sensi | 0.62620818 |
134 | MP0002233_abnormal_nose_morphology | 0.62565276 |
135 | MP0008789_abnormal_olfactory_epithelium | 0.62107309 |
136 | MP0002152_abnormal_brain_morphology | 0.61887213 |
137 | MP0002876_abnormal_thyroid_physiology | 0.61257955 |
138 | MP0003861_abnormal_nervous_system | 0.59170668 |
139 | MP0002160_abnormal_reproductive_system | 0.52690586 |
140 | MP0002234_abnormal_pharynx_morphology | 0.52687124 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of the axillary hair (HP:0100134) | 5.95341302 |
2 | Abnormality of secondary sexual hair (HP:0009888) | 5.95341302 |
3 | Abnormal sex determination (HP:0012244) | 5.30938361 |
4 | Sex reversal (HP:0012245) | 5.30938361 |
5 | Myokymia (HP:0002411) | 4.88963865 |
6 | Obstructive sleep apnea (HP:0002870) | 4.72217468 |
7 | Focal seizures (HP:0007359) | 4.40322553 |
8 | Febrile seizures (HP:0002373) | 4.21680623 |
9 | Abnormality of the corticospinal tract (HP:0002492) | 4.13875440 |
10 | Alacrima (HP:0000522) | 3.97703975 |
11 | Atonic seizures (HP:0010819) | 3.85352519 |
12 | Action tremor (HP:0002345) | 3.85276216 |
13 | Epileptic encephalopathy (HP:0200134) | 3.77594568 |
14 | Progressive cerebellar ataxia (HP:0002073) | 3.72814091 |
15 | Peripheral hypomyelination (HP:0007182) | 3.60893341 |
16 | Parakeratosis (HP:0001036) | 3.55125212 |
17 | Decreased lacrimation (HP:0000633) | 3.38287872 |
18 | Spastic gait (HP:0002064) | 3.37692793 |
19 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.36487933 |
20 | Optic nerve hypoplasia (HP:0000609) | 3.33636948 |
21 | Ankle clonus (HP:0011448) | 3.29538992 |
22 | Septo-optic dysplasia (HP:0100842) | 3.23482233 |
23 | Scanning speech (HP:0002168) | 3.23173225 |
24 | Generalized tonic-clonic seizures (HP:0002069) | 3.21001297 |
25 | Attenuation of retinal blood vessels (HP:0007843) | 3.19420016 |
26 | Limb dystonia (HP:0002451) | 3.15873458 |
27 | Abnormal eating behavior (HP:0100738) | 3.13016905 |
28 | Absent speech (HP:0001344) | 3.11039088 |
29 | Split foot (HP:0001839) | 3.07478141 |
30 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.06017514 |
31 | Absent/shortened dynein arms (HP:0200106) | 3.06017514 |
32 | Abnormal ciliary motility (HP:0012262) | 3.03170686 |
33 | Sleep apnea (HP:0010535) | 3.02078049 |
34 | White forelock (HP:0002211) | 3.00117286 |
35 | Dialeptic seizures (HP:0011146) | 2.98203196 |
36 | Hyperventilation (HP:0002883) | 2.96819507 |
37 | Urinary urgency (HP:0000012) | 2.93831228 |
38 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.92513886 |
39 | Patchy hypopigmentation of hair (HP:0011365) | 2.86453014 |
40 | Optic disc pallor (HP:0000543) | 2.83708890 |
41 | Absence seizures (HP:0002121) | 2.82218403 |
42 | Esotropia (HP:0000565) | 2.81625962 |
43 | Absent septum pellucidum (HP:0001331) | 2.81405990 |
44 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.80877347 |
45 | Polyphagia (HP:0002591) | 2.80226789 |
46 | Concave nail (HP:0001598) | 2.77564899 |
47 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.77110916 |
48 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.69859873 |
49 | Dysdiadochokinesis (HP:0002075) | 2.67436489 |
50 | Hemiparesis (HP:0001269) | 2.65479979 |
51 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.64834994 |
52 | Oligodactyly (hands) (HP:0001180) | 2.63906001 |
53 | Gait imbalance (HP:0002141) | 2.62952376 |
54 | Supranuclear gaze palsy (HP:0000605) | 2.61145300 |
55 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.60976810 |
56 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.60976810 |
57 | Abnormality of the septum pellucidum (HP:0007375) | 2.58880413 |
58 | True hermaphroditism (HP:0010459) | 2.57708155 |
59 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.57203476 |
60 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.57203476 |
61 | Nonprogressive disorder (HP:0003680) | 2.54740204 |
62 | Gaze-evoked nystagmus (HP:0000640) | 2.54719457 |
63 | Postural instability (HP:0002172) | 2.50599252 |
64 | Broad-based gait (HP:0002136) | 2.49157081 |
65 | Retinal dysplasia (HP:0007973) | 2.47103970 |
66 | Epileptiform EEG discharges (HP:0011182) | 2.44083492 |
67 | Lower limb muscle weakness (HP:0007340) | 2.43120799 |
68 | Drooling (HP:0002307) | 2.40960070 |
69 | Abnormality of binocular vision (HP:0011514) | 2.39909758 |
70 | Diplopia (HP:0000651) | 2.39909758 |
71 | Truncal ataxia (HP:0002078) | 2.38509577 |
72 | Thyroid-stimulating hormone excess (HP:0002925) | 2.38231428 |
73 | Chin dimple (HP:0010751) | 2.37752333 |
74 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.36649730 |
75 | Focal motor seizures (HP:0011153) | 2.34282361 |
76 | Dysmetria (HP:0001310) | 2.32083348 |
77 | Congenital sensorineural hearing impairment (HP:0008527) | 2.28088463 |
78 | Chronic hepatic failure (HP:0100626) | 2.25891421 |
79 | Increased circulating renin level (HP:0000848) | 2.25852073 |
80 | Torticollis (HP:0000473) | 2.24763595 |
81 | EEG with generalized epileptiform discharges (HP:0011198) | 2.24586174 |
82 | Gonadal dysgenesis (HP:0000133) | 2.21167967 |
83 | Intention tremor (HP:0002080) | 2.20920919 |
84 | Hypsarrhythmia (HP:0002521) | 2.20847804 |
85 | Excessive salivation (HP:0003781) | 2.20386052 |
86 | Neurofibrillary tangles (HP:0002185) | 2.20153748 |
87 | Mutism (HP:0002300) | 2.20122176 |
88 | Medial flaring of the eyebrow (HP:0010747) | 2.18881661 |
89 | Pancreatic fibrosis (HP:0100732) | 2.18658791 |
90 | Abnormality of macular pigmentation (HP:0008002) | 2.17292354 |
91 | Hypoplasia of the iris (HP:0007676) | 2.16718182 |
92 | Congenital primary aphakia (HP:0007707) | 2.16269984 |
93 | Amyotrophic lateral sclerosis (HP:0007354) | 2.15769818 |
94 | Hypomagnesemia (HP:0002917) | 2.15426122 |
95 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.14614651 |
96 | Molar tooth sign on MRI (HP:0002419) | 2.13663452 |
97 | Abnormality of midbrain morphology (HP:0002418) | 2.13663452 |
98 | Hemiplegia (HP:0002301) | 2.13630820 |
99 | Laryngomalacia (HP:0001601) | 2.10594254 |
100 | Cupped ear (HP:0000378) | 2.10311844 |
101 | Abnormality of the labia minora (HP:0012880) | 2.09741397 |
102 | Intellectual disability, moderate (HP:0002342) | 2.07751559 |
103 | Status epilepticus (HP:0002133) | 2.06915147 |
104 | Genital tract atresia (HP:0001827) | 2.06282970 |
105 | Onion bulb formation (HP:0003383) | 2.06047545 |
106 | Sensory axonal neuropathy (HP:0003390) | 2.04016950 |
107 | Tubulointerstitial nephritis (HP:0001970) | 2.03053215 |
108 | Genetic anticipation (HP:0003743) | 2.02980790 |
109 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.02947150 |
110 | Nephronophthisis (HP:0000090) | 2.01291451 |
111 | Nephrogenic diabetes insipidus (HP:0009806) | 1.99482645 |
112 | Osteomalacia (HP:0002749) | 1.99249833 |
113 | Vaginal atresia (HP:0000148) | 1.97831119 |
114 | Rhinitis (HP:0012384) | 1.97428297 |
115 | Pancreatic cysts (HP:0001737) | 1.97192373 |
116 | Abnormality of magnesium homeostasis (HP:0004921) | 1.96947451 |
117 | Generalized hypotonia (HP:0001290) | 1.96456673 |
118 | Renal Fanconi syndrome (HP:0001994) | 1.96112568 |
119 | Specific learning disability (HP:0001328) | 1.94831436 |
120 | Mixed hearing impairment (HP:0000410) | 1.93367683 |
121 | Conical tooth (HP:0000698) | 1.93288996 |
122 | Poor eye contact (HP:0000817) | 1.92088863 |
123 | Short tibia (HP:0005736) | 1.91822339 |
124 | Asplenia (HP:0001746) | 1.91256607 |
125 | 3-Methylglutaconic aciduria (HP:0003535) | 1.91002514 |
126 | Renal agenesis (HP:0000104) | 1.90892920 |
127 | Morphological abnormality of the inner ear (HP:0011390) | 1.89862051 |
128 | Decreased central vision (HP:0007663) | 1.89304758 |
129 | Bile duct proliferation (HP:0001408) | 1.88514680 |
130 | Abnormal biliary tract physiology (HP:0012439) | 1.88514680 |
131 | Increased hepatocellular lipid droplets (HP:0006565) | 1.88266156 |
132 | Supernumerary spleens (HP:0009799) | 1.88024194 |
133 | Male pseudohermaphroditism (HP:0000037) | 1.87163838 |
134 | Abnormal auditory evoked potentials (HP:0006958) | 1.87124138 |
135 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.86256741 |
136 | Amblyopia (HP:0000646) | 1.86060000 |
137 | Humeroradial synostosis (HP:0003041) | 1.85448211 |
138 | Synostosis involving the elbow (HP:0003938) | 1.85448211 |
139 | Paraplegia (HP:0010550) | 1.84688495 |
140 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.84450616 |
141 | Partial duplication of thumb phalanx (HP:0009944) | 1.84072364 |
142 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 1.83388127 |
143 | Chronic bronchitis (HP:0004469) | 1.83254905 |
144 | Impaired vibratory sensation (HP:0002495) | 1.83013989 |
145 | Polydipsia (HP:0001959) | 1.82600534 |
146 | Abnormal drinking behavior (HP:0030082) | 1.82600534 |
147 | Hypophosphatemic rickets (HP:0004912) | 1.82544678 |
148 | Hypoplastic pelvis (HP:0008839) | 1.81563667 |
149 | Upper limb muscle weakness (HP:0003484) | 1.81295572 |
150 | Spastic tetraplegia (HP:0002510) | 1.79473788 |
151 | Akinesia (HP:0002304) | 1.78207486 |
152 | Cerebral hypomyelination (HP:0006808) | 1.77202293 |
153 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.75201700 |
154 | Overfolded helix (HP:0000396) | 1.74794403 |
155 | Bronchiectasis (HP:0002110) | 1.74517293 |
156 | Pheochromocytoma (HP:0002666) | 1.74366474 |
157 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.73530996 |
158 | Oligodactyly (HP:0012165) | 1.72675063 |
159 | Focal dystonia (HP:0004373) | 1.72600765 |
160 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.71492991 |
161 | Nasolacrimal duct obstruction (HP:0000579) | 1.70947830 |
162 | Hypoplasia of the ulna (HP:0003022) | 1.70079796 |
163 | Atelectasis (HP:0100750) | 1.68177374 |
164 | Partial duplication of the phalanx of hand (HP:0009999) | 1.67690597 |
165 | Abnormality of renal resorption (HP:0011038) | 1.66630060 |
166 | Cutaneous finger syndactyly (HP:0010554) | 1.65628543 |
167 | Ulnar claw (HP:0001178) | 1.64985506 |
168 | Delayed myelination (HP:0012448) | 1.60869190 |
169 | Metabolic alkalosis (HP:0200114) | 1.60443433 |
170 | Abnormality of the renal medulla (HP:0100957) | 1.58485173 |
171 | Hypothermia (HP:0002045) | 1.58103397 |
172 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.58041788 |
173 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.56822045 |
174 | Flat occiput (HP:0005469) | 1.56786326 |
175 | Intestinal atresia (HP:0011100) | 1.56400085 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MKNK2 | 2.90929292 |
2 | MAP3K4 | 2.90858865 |
3 | PHKG2 | 2.56230330 |
4 | PHKG1 | 2.56230330 |
5 | PINK1 | 2.55783299 |
6 | MAPK15 | 2.45213171 |
7 | TLK1 | 2.39761962 |
8 | STK39 | 2.32803643 |
9 | TNIK | 2.25835956 |
10 | CASK | 10.1875743 |
11 | PKN1 | 1.94562204 |
12 | PAK6 | 1.93632904 |
13 | DAPK2 | 1.89594839 |
14 | MUSK | 1.87668237 |
15 | INSRR | 1.82017440 |
16 | STK16 | 1.74978782 |
17 | GRK1 | 1.73052166 |
18 | MINK1 | 1.72256731 |
19 | BLK | 1.60397569 |
20 | OXSR1 | 1.59522523 |
21 | MKNK1 | 1.57895228 |
22 | PLK2 | 1.46268072 |
23 | IRAK1 | 1.38973150 |
24 | CAMKK1 | 1.35353882 |
25 | FRK | 1.34494821 |
26 | IRAK2 | 1.34072436 |
27 | PRKD3 | 1.32849204 |
28 | NTRK3 | 1.32240278 |
29 | GRK7 | 1.29673039 |
30 | BMPR1B | 1.26136473 |
31 | FES | 1.24583401 |
32 | MAP2K4 | 1.24066883 |
33 | UHMK1 | 1.22002005 |
34 | TSSK6 | 1.21034098 |
35 | PRKCG | 1.20986689 |
36 | CLK1 | 1.18784727 |
37 | MAPKAPK5 | 1.16845496 |
38 | ERBB3 | 1.13796352 |
39 | MAP3K1 | 1.09581659 |
40 | FGR | 1.09508137 |
41 | SGK2 | 1.08335150 |
42 | IRAK4 | 1.08128960 |
43 | NEK6 | 1.06384386 |
44 | TYRO3 | 1.04826340 |
45 | PNCK | 1.03194702 |
46 | FGFR2 | 1.02898084 |
47 | PAK3 | 1.01498358 |
48 | MAPK13 | 1.00420890 |
49 | CAMKK2 | 1.00058305 |
50 | CAMK2B | 0.98588299 |
51 | DYRK2 | 0.97877980 |
52 | MAP3K9 | 0.97071158 |
53 | ADRBK2 | 0.96129116 |
54 | PAK2 | 0.94518228 |
55 | CDK3 | 0.90315293 |
56 | WNK4 | 0.86975821 |
57 | PBK | 0.83243744 |
58 | MARK1 | 0.82200574 |
59 | EPHB1 | 0.82092482 |
60 | YES1 | 0.81031275 |
61 | SRPK1 | 0.80359814 |
62 | HIPK2 | 0.77830053 |
63 | EPHA4 | 0.77426066 |
64 | NTRK2 | 0.76512852 |
65 | CSNK1G1 | 0.75788287 |
66 | CDK19 | 0.75761362 |
67 | PRKCZ | 0.74778103 |
68 | SIK2 | 0.74605603 |
69 | PRKCE | 0.72616958 |
70 | PRKD2 | 0.71149492 |
71 | SGK1 | 0.70639002 |
72 | KSR1 | 0.70549255 |
73 | CAMK2A | 0.68781769 |
74 | VRK1 | 0.68750551 |
75 | MET | 0.67385455 |
76 | ROCK2 | 0.67017980 |
77 | CAMK2D | 0.65645827 |
78 | PRKG1 | 0.64980844 |
79 | MAP4K2 | 0.63959632 |
80 | CSNK1G3 | 0.63129069 |
81 | MST4 | 0.61277257 |
82 | CDK15 | 0.60966015 |
83 | CDK18 | 0.60928238 |
84 | CDK14 | 0.59908246 |
85 | MARK2 | 0.59494992 |
86 | STK38 | 0.58592289 |
87 | ARAF | 0.57918889 |
88 | PIK3CG | 0.57276836 |
89 | DYRK1A | 0.56865659 |
90 | NTRK1 | 0.56826047 |
91 | EIF2AK2 | 0.56357801 |
92 | KSR2 | 0.56192745 |
93 | CAMK4 | 0.55653764 |
94 | DYRK3 | 0.55540043 |
95 | CDK11A | 0.54560146 |
96 | RPS6KA3 | 0.54204951 |
97 | PRKAA2 | 0.54177860 |
98 | CSNK1A1L | 0.53273299 |
99 | NME1 | 0.52891886 |
100 | TRIM28 | 0.52369362 |
101 | WNK1 | 0.51703516 |
102 | FER | 0.50889538 |
103 | SGK3 | 0.49797306 |
104 | CDK5 | 0.49681533 |
105 | CCNB1 | 0.48387469 |
106 | DAPK3 | 0.47891230 |
107 | MAP2K2 | 0.47885690 |
108 | NLK | 0.47563957 |
109 | CAMK1 | 0.45329680 |
110 | CSNK1G2 | 0.45272037 |
111 | CAMK2G | 0.45102821 |
112 | BMPR2 | 0.44607799 |
113 | PRPF4B | 0.44362279 |
114 | BCR | 0.44006779 |
115 | PRKD1 | 0.43791354 |
116 | LIMK1 | 0.42964331 |
117 | AKT3 | 0.41799556 |
118 | STK38L | 0.40923827 |
119 | RPS6KA5 | 0.40595481 |
120 | PRKCA | 0.40115787 |
121 | MAP2K7 | 0.40068896 |
122 | GSK3A | 0.39049520 |
123 | GRK5 | 0.36720042 |
124 | PRKACA | 0.35889947 |
125 | PRKCH | 0.35817399 |
126 | PAK1 | 0.34409940 |
127 | STK11 | 0.33988530 |
128 | ERBB2 | 0.33899491 |
129 | RET | 0.33246762 |
130 | DAPK1 | 0.33165463 |
131 | FYN | 0.31620519 |
132 | CSNK1D | 0.31590578 |
133 | DYRK1B | 0.31570391 |
134 | PRKCB | 0.31264586 |
135 | ACVR1B | 0.30962293 |
136 | TNK2 | 0.30087868 |
137 | MAP3K5 | 0.29827538 |
138 | ADRBK1 | 0.29616481 |
139 | PRKCQ | 0.28534518 |
140 | IRAK3 | 0.28011084 |
141 | EPHA3 | 0.25769089 |
142 | TAOK3 | 0.25231413 |
143 | SGK494 | 0.25200777 |
144 | SGK223 | 0.25200777 |
145 | WNK3 | 0.23983150 |
146 | CSNK1A1 | 0.23960852 |
147 | DMPK | 0.22689270 |
148 | MAPK10 | 0.22616312 |
149 | ERBB4 | 0.22030902 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protein export_Homo sapiens_hsa03060 | 3.64327136 |
2 | Phototransduction_Homo sapiens_hsa04744 | 2.86214881 |
3 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 2.31130056 |
4 | Nicotine addiction_Homo sapiens_hsa05033 | 2.30868777 |
5 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.28922915 |
6 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.23001347 |
7 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.17351430 |
8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.12335543 |
9 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.01658527 |
10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.94618262 |
11 | Axon guidance_Homo sapiens_hsa04360 | 1.93236843 |
12 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.90653730 |
13 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.90366084 |
14 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.82813093 |
15 | Long-term depression_Homo sapiens_hsa04730 | 1.80313312 |
16 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.76777805 |
17 | Taste transduction_Homo sapiens_hsa04742 | 1.72552095 |
18 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.72365229 |
19 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.68609687 |
20 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.65947271 |
21 | Morphine addiction_Homo sapiens_hsa05032 | 1.64614545 |
22 | Cocaine addiction_Homo sapiens_hsa05030 | 1.57414208 |
23 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.57126246 |
24 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.54476035 |
25 | Ribosome_Homo sapiens_hsa03010 | 1.50706961 |
26 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.49284226 |
27 | GABAergic synapse_Homo sapiens_hsa04727 | 1.45271142 |
28 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.44722510 |
29 | Alzheimers disease_Homo sapiens_hsa05010 | 1.33707923 |
30 | Parkinsons disease_Homo sapiens_hsa05012 | 1.32168888 |
31 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.30225294 |
32 | Other glycan degradation_Homo sapiens_hsa00511 | 1.28386775 |
33 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.25324010 |
34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.24617734 |
35 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.21544936 |
36 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.14911766 |
37 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.14199946 |
38 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.11612839 |
39 | Circadian entrainment_Homo sapiens_hsa04713 | 1.11198571 |
40 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.10506815 |
41 | Insulin secretion_Homo sapiens_hsa04911 | 1.09533608 |
42 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.08302146 |
43 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.08170481 |
44 | Bile secretion_Homo sapiens_hsa04976 | 1.06169651 |
45 | Salivary secretion_Homo sapiens_hsa04970 | 1.05955924 |
46 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.04091972 |
47 | Melanogenesis_Homo sapiens_hsa04916 | 1.03916742 |
48 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.02318302 |
49 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.01707809 |
50 | Renin secretion_Homo sapiens_hsa04924 | 0.97432729 |
51 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.96041469 |
52 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.93001655 |
53 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.92608421 |
54 | Histidine metabolism_Homo sapiens_hsa00340 | 0.92508181 |
55 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.92295387 |
56 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.90966428 |
57 | Huntingtons disease_Homo sapiens_hsa05016 | 0.90575237 |
58 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.89855406 |
59 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.89192644 |
60 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.88783382 |
61 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.88051341 |
62 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.86171786 |
63 | Asthma_Homo sapiens_hsa05310 | 0.84683322 |
64 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.84253004 |
65 | ABC transporters_Homo sapiens_hsa02010 | 0.83439394 |
66 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.81755283 |
67 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.78241262 |
68 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.77957371 |
69 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.77471252 |
70 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.77032229 |
71 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.74356729 |
72 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.74254124 |
73 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.74234124 |
74 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.74128863 |
75 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.73297582 |
76 | Gap junction_Homo sapiens_hsa04540 | 0.72320956 |
77 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.72198154 |
78 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.71920992 |
79 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.70689614 |
80 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.70503406 |
81 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.70498696 |
82 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.68414543 |
83 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.68024686 |
84 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.67013938 |
85 | Olfactory transduction_Homo sapiens_hsa04740 | 0.66378224 |
86 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.66368374 |
87 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64391865 |
88 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.63040372 |
89 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.61822727 |
90 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.61644054 |
91 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.60811323 |
92 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.59834329 |
93 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.59802614 |
94 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.59404828 |
95 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.58428635 |
96 | Alcoholism_Homo sapiens_hsa05034 | 0.56465028 |
97 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.55907216 |
98 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.53137877 |
99 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.52980435 |
100 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.52609005 |
101 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.51949363 |
102 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.51810674 |
103 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.50940895 |
104 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.49754247 |
105 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.49458043 |
106 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.47243944 |
107 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.46209286 |
108 | Circadian rhythm_Homo sapiens_hsa04710 | 0.46011939 |
109 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45839287 |
110 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.44412165 |
111 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.43845326 |
112 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.43747240 |
113 | Long-term potentiation_Homo sapiens_hsa04720 | 0.43347953 |
114 | Phagosome_Homo sapiens_hsa04145 | 0.42321868 |
115 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.40012100 |
116 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.39684879 |
117 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.39055072 |
118 | Prion diseases_Homo sapiens_hsa05020 | 0.38498828 |
119 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.37806059 |
120 | Melanoma_Homo sapiens_hsa05218 | 0.36554001 |
121 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.36346004 |
122 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.36271419 |
123 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.35612465 |
124 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.35247199 |
125 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.35116130 |
126 | Tight junction_Homo sapiens_hsa04530 | 0.34686850 |
127 | Basal transcription factors_Homo sapiens_hsa03022 | 0.34216198 |
128 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.32427953 |
129 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.32400659 |
130 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.32099217 |
131 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.32091929 |
132 | Peroxisome_Homo sapiens_hsa04146 | 0.30495233 |
133 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.28290296 |
134 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.27788776 |
135 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.27709764 |